sneha

Scopus Publications

Hormone-and cytokine-mediated signalling in the maintenance of bone balance
Avinash M Yadav, Gunjan Patil, Samruddhi Zende, Snehal Bhumkar, Sneha Sagarkar, Bhaskar Saha, Richa Ashma
Journal of Molecular Endocrinology, 2026
Bones form the skeletal framework, enabling movement, mineral balance, and hematopoiesis. Bone remodelling – tightly controlled by hormones, cytokines, and growth factors – is a dynamic process involving different cell types: osteoclasts, osteoblasts, and osteocytes; disrupted remodelling leads to disorders such as osteoporosis, arthritis, rickets, and osteomalacia. This review examines how osteoblast differentiation and bone metabolism are influenced by important hormonal regulators, including parathyroid hormone (PTH), which is the key regulator, followed by the effect of calcitonin, vitamin D, and insulin-like growth factor-1 (IGF-1), cytokines including transforming growth factor-beta, bone morphogenetic proteins, and immune modulators such as cluster of differentiation 40 (CD40)/and its ligand (CD40L). Their signalling pathways converge on key transcription factors – Runt-related transcription factor 2 (RUNX2), Osterix, and osteoprotegerin – and regulators – such as SMAD (suppressor of mothers against decapentaplegic) and mitogen-activated protein kinases (MAPKs) – coordinating osteoblast differentiation, bone matrix deposition, and mineralisation. We distinguish the effects of intermittent versus continuous parathormone administration and emphasise the dual genomic and non-genomic vitamin D actions and factors affecting its receptor expression. The PTH-regulated wingless-related integration site (Wnt)/β-catenin signalling is decisive for osteogenesis, and iPTH and cPTH exert distinct effects on osteoblastogenesis. The signalling pathways – SMAD-independent and SMAD-dependent – that control osteogenesis are analysed. The immune co-receptor CD40 interacts with CD40L to impact both osteoblasts and osteoclasts, linking immune responses and inflammation to bone health alterations. IGF-1 modulates osteoblast development and proliferation through mitogen-activated protein kinase (MEK) pathways. Understanding the molecular interactions among these pathways provides valuable insights into possible therapeutic targets for managing bone regeneration and bone disorders.
Histone Arginine Methylation Regulates Neuropeptide Y Expression in the Basolateral Amygdala to Promote Reward-Seeking Behaviour
Sneha Sagarkar, Deepa Rotti, Sahil Raykar, Gauri A. Upadhye, Amul J. Sakharkar
Cellular and Molecular Neurobiology, 2025
The basolateral amygdala (BLA) serves in the evaluation of reward. However, the causal molecular substrates in the BLA necessary for reward seeking behaviour are largely unknown. Reward conditioning induces long-lasting changes in epienzymes in limbic areas, including the amygdala. The current study probed the role of histone arginine methylation as a novel epigenetic mechanism in neuropeptide Y (NPY) gene regulation in the BLA during reward and reinforcement. For reward conditioning, adult Wistar rats were trained to self-administer sucrose pellets in a nose-poke operant chamber. Reward conditioning increased protein arginine methyltransferase 4 (PRMT4) and NPY in the BLA. Moreover, after operant conditioning, histone arginine methylation (H3R17me2a) and PRMT4 occupancy at the NPY promoter were heightened. PRMT4 was predominantly colocalised in the nucleus of the NPY-expressing cells in the BLA. Intra-BLA administration of specific siRNA or inhibitor of PRMT4 after conditioning waned the nose-poke activity, which was further reinstated during the subsequent 5 days. These effects of PRMT4 repression were correlated with the NPY expression and H3R17me2a levels at the NPY promoter. Furthermore, NPY peptide administration after PRMT4 siRNA or inhibitor infusion in BLA restored the nose-poke activity. PRMT4 is known to interact with CREB-binding protein (CBP). Therefore, co-occupancy of PRMT4 and CBP resulted in heightened histone acetylation (H3K14ac) in the conditioned rats. The current study suggests a pivotal role of PRMT4-mediated histone arginine methylation in NPY gene expression in the amygdala necessary for the reward-seeking behaviour.
Photoperiod-dependent expression of ‘Cocaine- and amphetamine-regulated transcript peptide’ and ‘Neuropeptide Y’ in the brain of anuran Minervarya syhadrensis
Ketaki Shetye, Sneha Sagarkar, Swapnil Shewale, Amul Sakharkar, Shobha Bhargava, Richa Ashma
General and Comparative Endocrinology, 2025
Profile of cocaine and amphetamine regulated transcript peptide (CARTp) and Corticotropin-releasing factor (CRF) in the brain of Euphlyctis cyanophlyctis during puddle desiccation
Swapnil A. Shewale, Sunil J. Koli, Sneha Sagarkar, Ameeta Ravikumar, Shobha Bhargava
Neuropeptides, 2025
AMPA and NMDA receptors in dentate gyrus mediate memory for sucrose in two port discrimination task
Sneha Sagarkar, Nagashree Bhat, Deepa Rotti, Nishikant K. Subhedar
Hippocampus, 2024
Although the phenomenon of memory formation and recall associated with the use of psychotropic drugs has been extensively studied, mechanisms underlying memories for natural reward have not been clarified. Herein, we test the hypothesis that glutamatergic receptors in the dentate gyrus play a role in memories associated with sucrose. We used pellet self‐administration protocol to generate memories in two‐port nose‐poke discrimination task using male Wistar rats. During non‐rewarded probe trial, the conditioned animals readily discriminated the active port versus inactive port and showed massive increase in mRNA expression of AMPA receptor subunit genes (gria2, gria3) as well as c‐Fos protein in the DG. Access to sweet pellet further enhanced c‐Fos expression in the DG. However, animals pre‐treated with AMPA receptor antagonist CNQX (intra‐DG), on exposure to operant chamber (no pellet), showed decreased discrimination as well as c‐Fos expression. We suggest that AMPA receptors in DG mediate recall and consolidation of memories associated with sucrose consumption. CNQX pre‐treated animals, if presented with sweet pellet on nose poke, exhibited high discrimination index coupled with increased c‐Fos expression. In these CNQX treated rats, the DI was again decreased following administration of NMDA receptor antagonist AP5. We suggest that, although AMPA receptors are blocked, the access to sweet pellet may induce surge of glutamate in the DG, which in turn may reinstate memories via activation of erstwhile silent synapses in NMDA dependant manner.
Diurnal modulations of neuropeptides ‘cocaine- and amphetamine- regulated transcript’ and ‘Neuropeptide Y’ in the brain of E. cyanophlyctis
Sunil Koli, Ketaki Shetye, Shobha Bhargava, Sneha Sagarkar
Biological Rhythm Research, 2024
Mate calling alters expression of neuropeptide, cocaine- and amphetamine- regulated transcript (CART) in the brain of male frog Microhyla nilphamariensis
Shobha Bhargava, Ketaki Shetye, Swapnil Shewale, Nitin Sawant, Sneha Sagarkar, Nishikant Subhedar
Neuropeptides, 2023
TET1-induced DNA demethylation in dentate gyrus is important for reward conditioning and reinforcement
Sneha Sagarkar, Nagashree Bhat, Madhura Sapre, Biru Dudhabhate, Dadasaheb M. Kokare, Nishikant K. Subhedar, Amul J. Sakharkar
Molecular Neurobiology, 2022
Reproductive phase related variations in the expression of neuropeptide, cocaine- and amphetamine- regulated transcript (CART) in the brain and pituitary gland of adult male Microhyla ornata
Kavita N. Hadawale, Swapnil A. Shewale, Ketaki C. Shetye, Sneha Sagarkar, Amul J. Sakharkar, Shobha Y. Bhargava
Neuroscience Letters, 2022
Neuroplastic Changes in the Superior Colliculus and Hippocampus in Self-rewarding Paradigm: Importance of Visual Cues
Sanjay N. Awathale, Akash M. Waghade, Harish M. Kawade, Gouri Jadhav, Amit G. Choudhary, Sneha Sagarkar, Amul J. Sakharkar, Nishikant K. Subhedar, Dadasaheb M. Kokare
Molecular Neurobiology, 2022
Coincident excitation via different sensory modalities encoding objects of positive salience is known to facilitate learning and memory. With a view to dissect the contribution of visual cues in inducing adaptive neural changes, we monitored the lever press activity of a rat conditioned to self-administer sweet food pellets in the presence/absence of light cues. Application of light cues facilitated learning and consolidation of long-term memory. The superior colliculus (SC) of rats trained on light cue showed increased neuronal activity, dendritic branching, and brain-derived neurotrophic factor (BDNF) protein and mRNA expression. Concomitantly, the hippocampus showed augmented neurogenesis as well as BDNF protein and mRNA expression. While intra-SC administration of U0126 (inhibitor of ERK 1/2 and long-term memory) impaired memory formation, lidocaine (local anaesthetic) hindered memory recall. The light cue-dependent sweet food pellet self-administration was coupled with increased efflux of dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) in the nucleus accumbens shell (AcbSh). In conditioned rats, pharmacological inhibition of glutamatergic signalling in dentate gyrus (DG) reduced lever press activity, as well as DA and DOPAC secretion in the AcbSh. We suggest that the neuroplastic changes in the SC and hippocampus might represent memory engrams sculpted by visual cues encoding reward information.
Role for Histone Deacetylation in Traumatic Brain Injury-Induced Deficits in Neuropeptide y in Arcuate Nucleus: Possible Implications in Feeding Behavior
Nagalakshmi Balasubramanian, Sneha Sagarkar, Meha Jadhav, Navneet Shahi, Richa Sirmaur, Amul J. Sakharkar
Neuroendocrinology, 2021
LSD1-BDNF activity in lateral hypothalamus-medial forebrain bundle area is essential for reward seeking behavior
Sneha Sagarkar, Amit G. Choudhary, Nagalakshmi Balasubramanian, Sanjay N. Awathale, Amita R. Somalwar, Namrata Pawar, Dadasaheb M. Kokare, Nishikant K. Subhedar, Amul J. Sakharkar
Progress in Neurobiology, 2021
Epigenetic Blockade of Hippocampal SOD2 Via DNMT3b-Mediated DNA Methylation: Implications in Mild Traumatic Brain Injury-Induced Persistent Oxidative Damage
Nagalakshmi Balasubramanian, Sneha Sagarkar, Amit G. Choudhary, Dadasaheb M. Kokare, Amul J. Sakharkar
Molecular Neurobiology, 2021
Brain profiling of endogenous Neuropeptide Y (NPY) in distinct reproductive phases of adult male Microhyla ornata
Kavita N. Hadawale, Sneha Sagarkar, Shobha Y. Bhargava
Neuroscience Letters, 2021
Repeated mild traumatic brain injury induces persistent variations in mitochondrial DNA copy number in mesocorticolimbic neurocircuitry of the rat
Nagalakshmi Balasubramanian, Abhinav Srivastava, Namrata Pawar, Sneha Sagarkar, Amul J. Sakharkar
Neuroscience Research, 2020
Repeated mild traumatic brain injury affects microbial diversity in rat jejunum
Dollwin Matharu, Dhiraj Dhotre, Nagalakshmi Balasubramanian, Namrata Pawar, Sneha Sagarkar, Amul Sakharkar
Journal of Biosciences, 2019
Repeated mild traumatic brain injury affects microbial diversity in rat jejunum
Journal of Biosciences, 2019
Repeated mild traumatic brain injury causes persistent changes in histone deacetylase function in hippocampus: Implications in learning and memory deficits in rats
Sneha Sagarkar, Nagalakshmi Balasubramanian, Shruti Mishra, Amit G. Choudhary, Dadasaheb M. Kokare, Amul J. Sakharkar
Brain Research, 2019
Thyrotropin-releasing hormone (TRH) in the brain and pituitary of the teleost, Clarias batrachus and its role in regulation of hypophysiotropic dopamine neurons
Omprakash Singh, Dipti R. Pradhan, B. Nagalakashmi, Santosh Kumar, Saptarsi Mitra, Sneha Sagarkar, Amul J. Sakharkar, Ronald M. Lechan, Praful S. Singru
Journal of Comparative Neurology, 2019
Sex-specific distribution of Neuropeptide Y (NPY) in the brain of the frog, Microhyla ornata
Kavita N. Hadawale, Nitin S. Sawant, Sneha Sagarkar, Amul J. Sakharkar, Shobha Y. Bhargava
Neuropeptides, 2019
Neuropeptide CART prevents memory loss attributed to withdrawal of nicotine following chronic treatment in mice
Chandrashekhar D. Borkar, Sneha Sagarkar, Amul J. Sakharkar, Nishikant K. Subhedar, Dadasaheb M. Kokare
Addiction Biology, 2019
Cocaine- and amphetamine-regulated transcript peptide (CART) induced reward behavior is mediated via Gi/o dependent phosphorylation of PKA/ERK/CREB pathway
Amita R. Somalwar, Amit G. Choudhary, Pravesh R. Sharma, Nagalakshmi B., Sneha Sagarkar, Amul J. Sakharkar, Nishikant K. Subhedar, Dadasaheb M. Kokare
Behavioural Brain Research, 2018
CART neurons in the lateral hypothalamus communicate with the nucleus accumbens shell via glutamatergic neurons in paraventricular thalamic nucleus to modulate reward behavior
Amit G. Choudhary, Amita R. Somalwar, Sneha Sagarkar, Abhishek Rale, Amul Sakharkar, Nishikant K. Subhedar, Dadasaheb M. Kokare
Brain Structure and Function, 2018
Epigenetic Mechanisms of Traumatic Brain Injuries
Nagalakshmi B., Sneha Sagarkar, Amul J. Sakharkar
Progress in Molecular Biology and Translational Science, 2018
Minimal traumatic brain injury causes persistent changes in DNA methylation at BDNF gene promoters in rat amygdala: A possible role in anxiety-like behaviors
Sneha Sagarkar, Tanmayi Bhamburkar, Gajanan Shelkar, Amit Choudhary, Dadasaheb M. Kokare, Amul J. Sakharkar
Neurobiology of Disease, 2017
Traumatic stress-induced persistent changes in DNA methylation regulate neuropeptide Y expression in rat jejunum
S. Sagarkar, S. Mahajan, A. G. Choudhary, C. D. Borkar, D. M. Kokare, A. J. Sakharkar
Neurogastroenterology and Motility, 2017
Epigenetics and alcohol use disorders
S. Sagarkar, A. Sakharkar
Neuropsychiatric Disorders and Epigenetics, 2017
Atrazine exposure causes mitochondrial toxicity in liver and muscle cell lines
Atya Kapley, Sneha Sagarkar, Deepa Gandhi, SSaravana Devi, Amul Sakharkar
Indian Journal of Pharmacology, 2016
s-triazine degrading bacterial isolate Arthrobacter sp. AK-YN10, a candidate for bioaugmentation of atrazine contaminated soil
Sneha Sagarkar, Pooja Bhardwaj, Veronika Storck, Marion Devers-Lamrani, Fabrice Martin-Laurent, Atya Kapley
Applied Microbiology and Biotechnology, 2016
Antimicrobial activity of Alcaligenes sp. HPC 1271 against multidrug resistant bacteria
Atya Kapley, Himgouri Tanksale, Sneha Sagarkar, A. R. Prasad, Rathod Aravind Kumar, Nandita Sharma, Asifa Qureshi, Hemant J. Purohit
Functional and Integrative Genomics, 2016
Bioremediation strategies for removal of residual atrazine in the boreal groundwater zone
Aura O. Nousiainen, Katarina Björklöf, Sneha Sagarkar, Jeppe Lund Nielsen, Atya Kapley, Kirsten S. Jørgensen
Applied Microbiology and Biotechnology, 2015
Mapping atrazine and phenol degradation genes in Pseudomonas sp. EGD-AKN5
Pooja Bhardwaj, Abhinav Sharma, Sneha Sagarkar, Atya Kapley
Biochemical Engineering Journal, 2015
Soil mesocosm studies on atrazine bioremediation
Sneha Sagarkar, Aura Nousiainen, Shraddha Shaligram, Katarina Björklöf, Kristina Lindström, Kirsten S. Jørgensen, Atya Kapley
Journal of Environmental Management, 2014
Atrazine degradation in boreal nonagricultural subsoil and tropical agricultural soil
Aura O. Nousiainen, Katarina Björklöf, Sneha Sagarkar, Shinjini Mukherjee, Hemant J. Purohit, Atya Kapley, Kirsten S. Jørgensen
Journal of Soils and Sediments, 2014
Draft genome sequence of atrazine-utilizing bacteria isolated from Indian agricultural soil
Genome Announcements, 2014
Genome sequence of Alcaligenes sp. strain HPC1271
Atya Kapley, Sneha Sagarkar, Himgouri Tanksale, Nandita Sharma, Asifa Qureshi, Anshuman Khardenavis, Hemant J. Purohit
Genome Announcements, 2013
Monitoring bioremediation of atrazine in soil microcosms using molecular tools
Sneha Sagarkar, Shinjini Mukherjee, Aura Nousiainen, Katarina Björklöf, Hemant J. Purohit, Kirsten S. Jørgensen, Atya Kapley
Environmental Pollution, 2013

RECENT SCHOLAR PUBLICATIONS

Hormone-and cytokine-mediated signalling in the maintenance of bone balance
AM Yadav, G Patil, S Zende, S Bhumkar, S Sagarkar, B Saha, R Ashma
Journal of Molecular Endocrinology 76 (2) , 2026
2026
Citations: 1
Premarital Genetic Compatibility Matching: A Public Health Perspective
S Sagarkar
Indian Journal of Community Medicine, 10.4103 , 2026
2026
Histone Arginine Methylation Regulates Neuropeptide Y Expression in the Basolateral Amygdala to Promote Reward-Seeking Behaviour
S Sagarkar, D Rotti, S Raykar, GA Upadhye, AJ Sakharkar
Cellular and Molecular Neurobiology 45 (1), 1-21 , 2025
2025
Homozygous Nonsense Variant in the GJA4 Gene Associated With Increased Fetal Nuchal Fold Thickness and Abnormal Fetal Ductus Venosus Termination: A Case Report
BCNAPSSPMTKSVSVVTPM Tamhankar
Cureus 17 (11), e97033 , 2025
2025
Photoperiod-dependent expression of ‘Cocaine-and amphetamine-regulated transcript peptide’and ‘Neuropeptide Y’in the brain of anuran Minervarya syhadrensis
K Shetye, S Sagarkar, S Shewale, A Sakharkar, S Bhargava, R Ashma
General and Comparative Endocrinology, 114820 , 2025
2025
Genetic Evaluation of Global Developmental Delay in Children: A Series of Seven Cases
MS Menon Pramila, Majjigudda Renuka, Sagarkar Sneha, Tamhankar Parag
Journal of Clinical and Diagnostics Research 19 (6), GR01 - GR06 , 2025
2025
Profile of cocaine and amphetamine regulated transcript peptide (CARTp) and Corticotropin-releasing factor (CRF) in the brain of Euphlyctis cyanophlyctis during puddle desiccation
SA Shewale, SJ Koli, S Sagarkar, A Ravikumar, S Bhargava
Neuropeptides 111, 102518 , 2025
2025
Diurnal modulations of neuropeptides ‘cocaine- and amphetamine- regulated transcript’ and ‘Neuropeptide Y’ in the brain of E. cyanophlyctis
S Koli, K Shetye, S Bhargava, S Sagarkar
Biological Rhythm Research 55 (11-12), 495-508 , 2024
2024
Citations: 1
AMPA and NMDA receptors in dentate gyrus mediate memory for sucrose in two port discrimination task
NKS Sneha Sagarkar, Nagashree Bhat, Deepa Rotti
Hippocampus, 1-15 , 2024
2024
Citations: 4
Mate calling alters expression of neuropeptide, cocaine-and amphetamine-regulated transcript (CART) in the brain of male frog Microhyla nilphamariensis
S Bhargava, K Shetye, S Shewale, N Sawant, S Sagarkar, N Subhedar
Neuropeptides 102, 102380 , 2023
2023
Citations: 3
TET1-induced DNA demethylation in dentate gyrus is important for reward conditioning and reinforcement
S Sagarkar, N Bhat, M Sapre, B Dudhabhate, DM Kokare, NK Subhedar, ...
Molecular Neurobiology 59 (9), 5426-5442 , 2022
2022
Citations: 12
Reproductive phase related variations in the expression of neuropeptide, cocaine-and amphetamine-regulated transcript (CART) in the brain and pituitary gland of adult male …
KN Hadawale, SA Shewale, KC Shetye, S Sagarkar, AJ Sakharkar, ...
Neuroscience Letters 786, 136783 , 2022
2022
Citations: 4
Neuroplastic changes in the superior colliculus and hippocampus in self-rewarding paradigm: importance of visual cues
SN Awathale, AM Waghade, HM Kawade, G Jadhav, AG Choudhary, ...
Molecular Neurobiology 59 (2), 890-915 , 2022
2022
Citations: 22
Role for histone deacetylation in traumatic brain injury-induced deficits in neuropeptide Y in arcuate nucleus: possible implications in feeding behavior
N Balasubramanian, S Sagarkar, M Jadhav, N Shahi, R Sirmaur, ...
Neuroendocrinology 111 (12), 1187-1200 , 2021
2021
Citations: 20
LSD1-BDNF activity in lateral hypothalamus-medial forebrain bundle area is essential for reward seeking behavior
S Sagarkar, AG Choudhary, N Balasubramanian, SN Awathale, ...
Progress in neurobiology 202, 102048 , 2021
2021
Citations: 29
Epigenetic blockade of hippocampal SOD2 via DNMT3b-mediated DNA methylation: implications in mild traumatic brain injury-induced persistent oxidative damage
N Balasubramanian, S Sagarkar, AG Choudhary, DM Kokare, ...
Molecular Neurobiology 58 (3), 1162-1184 , 2021
2021
Citations: 34
Brain profiling of endogenous Neuropeptide Y (NPY) in distinct reproductive phases of adult male Microhyla ornata
KN Hadawale, S Sagarkar, SY Bhargava
Neuroscience Letters 740, 135409 , 2021
2021
Citations: 4
Repeated mild traumatic brain injury induces persistent variations in mitochondrial DNA copy number in mesocorticolimbic neurocircuitry of the rat
N Balasubramanian, A Srivastava, N Pawar, S Sagarkar, AJ Sakharkar
Neuroscience research 155, 34-42 , 2020
2020
Citations: 11
Repeated mild traumatic brain injury affects microbial diversity in rat jejunum: Dollwin Matharu et al.
D Matharu, D Dhotre, N Balasubramanian, N Pawar, S Sagarkar, ...
Journal of biosciences 44 (5), 120 , 2019
2019
Citations: 38
Repeated mild traumatic brain injury causes persistent changes in histone deacetylase function in hippocampus: Implications in learning and memory deficits in rats
S Sagarkar, N Balasubramanian, S Mishra, AG Choudhary, DM Kokare, ...
Brain research 1711, 183-192 , 2019
2019
Citations: 41

MOST CITED SCHOLAR PUBLICATIONS

Monitoring bioremediation of atrazine in soil microcosms using molecular tools
S Sagarkar, S Mukherjee, A Nousiainen, K Björklöf, HJ Purohit, ...
Environmental pollution 172, 108-115 , 2013
2013
Citations: 99
Soil mesocosm studies on atrazine bioremediation
S Sagarkar, A Nousiainen, S Shaligram, K Björklöf, K Lindström, ...
Journal of environmental management 139, 208-216 , 2014
2014
Citations: 77
Minimal traumatic brain injury causes persistent changes in DNA methylation at BDNF gene promoters in rat amygdala: a possible role in anxiety-like behaviors
S Sagarkar, T Bhamburkar, G Shelkar, A Choudhary, DM Kokare, ...
Neurobiology of Disease 106, 101-109 , 2017
2017
Citations: 70
Atrazine exposure causes mitochondrial toxicity in liver and muscle cell lines
S Sagarkar, D Gandhi, SS Devi, A Sakharkar, A Kapley
Indian Journal of Pharmacology 48 (2), 200-207 , 2016
2016
Citations: 63
s -triazine degrading bacterial isolate Arthrobacter sp. AK-YN10, a candidate for bioaugmentation of atrazine contaminated soil
S Sagarkar, P Bhardwaj, V Storck, M Devers-Lamrani, F Martin-Laurent, ...
Applied microbiology and biotechnology 100 (2), 903-913 , 2016
2016
Citations: 62
Epigenetic mechanisms of traumatic brain injuries
B Nagalakshmi, S Sagarkar, AJ Sakharkar
Progress in molecular biology and translational science 157, 263-298 , 2018
2018
Citations: 49
Bioremediation strategies for removal of residual atrazine in the boreal groundwater zone
AO Nousiainen, K Björklöf, S Sagarkar, JL Nielsen, A Kapley, ...
Applied microbiology and biotechnology 99 (23), 10249-10259 , 2015
2015
Citations: 44
CART neurons in the lateral hypothalamus communicate with the nucleus accumbens shell via glutamatergic neurons in paraventricular thalamic nucleus to modulate reward behavior
DMK Amit G. Choudhary, Amita R. Somalwar, Sneha Sagarkar, Abhishek Rale ...
Brain structure function , 2017
2017
Citations: 43
Mapping atrazine and phenol degradation genes in Pseudomonas sp. EGD-AKN5
P Bhardwaj, A Sharma, S Sagarkar, A Kapley
Biochemical Engineering Journal 102, 125-134 , 2015
2015
Citations: 42
Repeated mild traumatic brain injury causes persistent changes in histone deacetylase function in hippocampus: Implications in learning and memory deficits in rats
S Sagarkar, N Balasubramanian, S Mishra, AG Choudhary, DM Kokare, ...
Brain research 1711, 183-192 , 2019
2019
Citations: 41
Repeated mild traumatic brain injury affects microbial diversity in rat jejunum: Dollwin Matharu et al.
D Matharu, D Dhotre, N Balasubramanian, N Pawar, S Sagarkar, ...
Journal of biosciences 44 (5), 120 , 2019
2019
Citations: 38
Antimicrobial activity of Alcaligenes sp . HPC 1271 against multidrug resistant bacteria
A Kapley, H Tanksale, S Sagarkar, AR Prasad, RA Kumar, N Sharma, ...
Functional & integrative genomics 16 (1), 57-65 , 2016
2016
Citations: 37
Epigenetic blockade of hippocampal SOD2 via DNMT3b-mediated DNA methylation: implications in mild traumatic brain injury-induced persistent oxidative damage
N Balasubramanian, S Sagarkar, AG Choudhary, DM Kokare, ...
Molecular Neurobiology 58 (3), 1162-1184 , 2021
2021
Citations: 34
LSD1-BDNF activity in lateral hypothalamus-medial forebrain bundle area is essential for reward seeking behavior
S Sagarkar, AG Choudhary, N Balasubramanian, SN Awathale, ...
Progress in neurobiology 202, 102048 , 2021
2021
Citations: 29
Cocaine-and amphetamine-regulated transcript peptide (CART) induced reward behavior is mediated via Gi/o dependent phosphorylation of PKA/ERK/CREB pathway
AR Somalwar, AG Choudhary, PR Sharma, S Sagarkar, AJ Sakharkar, ...
Behavioural brain research 348, 9-21 , 2018
2018
Citations: 28
Neuroplastic changes in the superior colliculus and hippocampus in self-rewarding paradigm: importance of visual cues
SN Awathale, AM Waghade, HM Kawade, G Jadhav, AG Choudhary, ...
Molecular Neurobiology 59 (2), 890-915 , 2022
2022
Citations: 22
Atrazine degradation in boreal nonagricultural subsoil and tropical agricultural soil
AO Nousiainen, K Björklöf, S Sagarkar, S Mukherjee, HJ Purohit, ...
Journal of soils and sediments 14 (6), 1179-1188 , 2014
2014
Citations: 22
Role for histone deacetylation in traumatic brain injury-induced deficits in neuropeptide Y in arcuate nucleus: possible implications in feeding behavior
N Balasubramanian, S Sagarkar, M Jadhav, N Shahi, R Sirmaur, ...
Neuroendocrinology 111 (12), 1187-1200 , 2021
2021
Citations: 20
Neuropeptide CART prevents memory loss attributed to withdrawal of nicotine following chronic treatment in mice
CD Borkar, S Sagarkar, AJ Sakharkar, NK Subhedar, DM Kokare
Addiction Biology 24 (1), 51-64 , 2019
2019
Citations: 16
Thyrotropin‐releasing hormone (TRH) in the brain and pituitary of the teleost, Clarias batrachus and its role in regulation of hypophysiotropic dopamine neurons
O Singh, DR Pradhan, B Nagalakashmi, S Kumar, S Mitra, S Sagarkar, ...
Journal of Comparative Neurology 527 (6), 1070-1101 , 2019
2019
Citations: 15

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MOST CITED SCHOLAR PUBLICATIONS

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