Involvement of CB1 cannabinoid receptors in methamphetamine-related decision-making and social behavior deficits Tahoora Mousavi, Nadia Hatami, Saba Niknamfar, Mahshid Naseri, Raheleh Rafaiee, Seyedeh Masoumeh Seyedhosseini Tamijani, Mohammad Saleh Ranaiy, Hamed Ghazvini BMC Neuroscience, 2026 Methamphetamine (METH) abuse is associated with profound cognitive and behavioral impairments, notably in decision-making and social interaction. Emerging evidence suggests the endocannabinoid system, particularly CB1 receptors (CB1Rs), plays a modulatory role in these processes. This study investigated whether pharmacological modulation of CB1Rs can alter METH-induced deficits in decision-making, social behavior, and anxiety in a rodent model. Adult male Wistar rats were administered METH and treated with either a CB1R agonist WIN55,212-2 (WIN; 3 mg/kg; i.p) or antagonist (Rimonabant;1 mg/kg; i.p.). Behavioral assessments included effort-based decision-making via the Y-maze barrier task, social behavior tests, and anxiety evaluation using the elevated plus maze. METH exposure significantly reduced high-reward choices in effort-based tasks and impaired multiple domains of social behavior. It also induced anxiety-like behaviors. Rimonabant treatment partially reversed these effects, improving decision-making performance, enhancing social interactions, and reducing anxiety-related responses. In contrast, WIN did not significantly alleviate METH-induced behavioral impairments. CB1R antagonism via Rimonabant may mitigate METH-induced cognitive and social deficits, underscoring the therapeutic potential of targeting the endocannabinoid system in stimulant-related neuropsychiatric disorders. These findings highlight CB1R antagonists as promising agents for future interventions in METH addiction and its associated behavioral disruptions. Not applicable.
Preclinical evidence for statin modulation of analgesic tolerance and substance use disorders: a narrative review Mohammad Saleh Ranaiy, Seyedeh Masoumeh Seyedhosseini Tamijani, Hamed Ghazvini, Kamaledin Alaedini Shourmasti, Raheleh Rafaiee American Journal of Drug and Alcohol Abuse, 2026 Preclinical evidence suggests that statins, particularly lipophilic agents, may influence neural and behavioral mechanisms underlying addiction through anti-inflammatory and neuromodulatory actions. These findings highlight a promising translational avenue for adjunctive use of statins in SUDs, warranting further mechanistic and clinical studies.
Circadian rhythms and human studies: methodology, challenges, and future directions in research Hamideh Rahmati, Behzad Garmabi, Hamed Ghazvini, Seyedeh Masoumeh Seyedhosseini Tamijani, Mohammad Niroumand Sarvandani, Raheleh Rafaiee Biological Rhythm Research, 2026 Circadian rhythms are fundamental biological cycles that regulate essential physiological processes, metabolism, immune function, and cardiovascular health. Disruption of these rhythms due to modern lifestyles, shift work, or environmental factors has been implicated in a broad spectrum of health disorders, ranging from metabolic and cardiovascular diseases to mental health conditions and cancer. This narrative review examines human experimental, observational and intervention models employed in circadian research, including forced desynchrony protocols, constant routine protocols, and studies of natural settings, highlighting their contributions to understanding the mechanisms and impacts of circadian misalignment. Furthermore, it explores interventions such as light therapy, chrononutrition, and pharmacological approaches aimed at reducing the adverse effects of circadian disruption. Emerging technologies like wearable devices, omics-based biomarkers, and artificial intelligence are also discussed as transformative tools in circadian research. The review underscores the urgent need for interdisciplinary approaches and translational strategies to incorporate circadian science into clinical practice and public health policies. By addressing methodological challenges and leveraging novel technologies, future research can inform personalized interventions to improve health outcomes in an increasingly disrupted world.
Neuroprotective Effects of Erythropoietin in Fetal Alcohol Spectrum Disorder: BDNF Upregulation, Reduced Astrogliosis, and Anxiety Relief Raheleh Rafaiee, Fahimeh Mohseni Journal of Studies on Alcohol and Drugs, 2025 Objective: The term fetal alcohol spectrum disorder (FASD) refers to a variety of negative consequences that may develop in children born to women who have consumed alcohol during pregnancy. Anxiety disorders are common in FASD. Animals exposed to alcohol exhibit anxiety-like traits. Erythropoietin (EPO) is produced by the kidneys and liver. The synthesis of EPO by immature neurons also plays a crucial role in the embryonic stage. In addition, EPO inhibits astrogliosis and cell death while increasing the number of brain-derived neurotrophic factor (BDNF)-positive cells, which is linked to reductions in anxiety-like behavior and neuronal damage. This study investigated the protective effects of EPO on ethanol-induced neurotoxicity in the hippocampus of rat pups. Method: The intubation of the total daily dose of ethanol (5/27 g/kg/day) was started from Postnatal Day 2 (PD2) to PD10 (corresponding to the third trimester of pregnancy in humans). After intubation, 1,000 and 2,000 U/kg EPO were injected subcutaneously. The elevated plus maze was performed 39 days after the birth of the pups to determine the levels of anxiety. Immunohistochemical staining was then performed to determine GFAP and BDNF levels 40 days after birth. Nissl staining was done to measure necrotic cell death. Results: EPO administration significantly improved the anxious behavior associated with FASD (p < .001). EPO significantly increased BDNF levels (p < .001), decreased glial fibrillary acidic protein expression (p < .001), and attenuated alcohol neurotoxicity-induced necrotic cell death (p < .001). Conclusions: EPO treatment provides protection against ethanol neurotoxicity, which consequently leads to lower anxiety levels.
Quantitative Electroencephalographic Biomarkers for Repetitive Transcranial Magnetic Stimulation Treatment Response Prediction in Mild Cognitive Impairment: A Pilot Study Protocol for Multi-Center, Assessor-Blinded, Open-Label Clinical Trial Zahra Yousefian, Seyed Hamzeh Hosseini, Mohammad Ali Nazari, Reza Kazemi, Mohammad Asghari‐Jafarabadi, Hamed Ghazvini, Raheleh Rafaiee, Seyedeh Masoumeh Seyedhosseini Tamijani Brain and Behavior, 2025 Rationale Over 55 million people worldwide suffer from dementia, with 10 million new cases diagnosed annually. Due to the limited efficacy of drug therapies, alternative approaches like repetitive transcranial magnetic stimulation (rTMS) have gained popularity as a non‐invasive, safe method leveraging neural plasticity and brain connectivity. However, its high cost and time commitment highlight the need for biomarkers to predict treatment response. Aims This pilot study aims to identify a quantitative electroencephalography (QEEG) biomarker to predict which mild cognitive impairment patients will respond to rTMS. By targeting responders early, clinicians can make rTMS more cost‐effective and time‐efficient, reducing wasted treatment on non‐responders. Design This multi‐center, assessor‐blinded clinical trial will examine QEEG biomarkers as predictors of rTMS treatment responsiveness in 25 patients with mild cognitive impairment (MCI). Adults aged 60 years or older will undergo cognitive assessments using the Montreal Cognitive Assessment (MoCA) or mini‐mental state examination (MMSE) and have an electroencephalography (EEG) recording. Participants will complete 10 rTMS sessions targeting the left DLPFC over 2 weeks, with 2000 pulses per session at 20 Hz. Cognitive tests will be repeated post‐treatment, and participants will be classified as responders or non‐responders based on cognitive changes, then baseline QEEG parameters will be compared between the two groups. The primary endpoint is the proportion of responders at ten sessions after rTMS (score post‐intervention > score pre‐intervention = responder, according to the minimal clinically important difference (MCID) threshold (i.e., an increase of at least 3 points or 10% on the MMSE, or an increase of at least 1 point on the MoCA); score post‐intervention ≤ score pre‐intervention = non‐responder). The secondary endpoints are the differences in baseline QEEG features between responders and non‐responders. Outcome By identifying responders prior to treatment, we can optimize resource allocation, minimize the time and cost associated with ineffective treatments, and ultimately improve the quality of care for individuals with MCI. Trial Registration IRCT registration number: IRCT20240218061042N1 (version updated September 7, 2024)
Protest-related Suicide against Socio-political Conditions Raheleh Rafaiee, Fahimeh Mohseni Indian Journal of Social Psychiatry, 2025 Dear Editor, Suicide is one of the important social issues worldwide. Social problems are the primary drivers of protest suicides, though individual personality traits may contribute to the specific manifestation and outcome of these tragic events. Protest suicides are often deliberate acts aimed at inspiring collective action, rather than impulsive decisions, as evidenced by detailed suicide notes left by the deceased.[1] Protest suicides have been notably prevalent in South Korea, where they have emerged as a significant form of political expression, with nearly 100 recorded between 1970 and 2003, protesting against government oppression and labor exploitation. This phenomenon reflects deep societal issues and has historical roots in the country’s struggle for democracy.[1,2] Also, in Hong Kong, in 2019, protests against the anti-extradition law, protest-related suicides were reported.[3] The protest suicides in the Middle Eastern and North African (MENA) regions are deeply rooted in historical and cultural contexts, influenced by factors such as mental health stigma, gender dynamics, and socio-political conditions. These elements converge to create a landscape where individuals, particularly women, may resort to self-immolation or other forms of suicide as a form of protest or escape. Moreover, the MENA region exhibits a significant lack of mental health services, leading to a lack of timely intervention in psychiatric emergencies. Cultural norms, including patriarchy and limited women’s rights (for instance, Blue Girl[4]) contribute to high protest suicide rates, especially through methods like self-immolation. Honor-related suicides among women reflect oppressive societal values, where traditional expectations can lead to self-destructive behaviors. Job instability, multiple wars, and forced migration exacerbate mental health issues, pushing individuals toward suicide as a form of protest against their existing conditions in MENA.[5] The increasing trend of protest suicide among youth in the MENA highlights the urgent need for effective mental health interventions and policy changes.[5] It is essential to note that not all individuals in these contexts resort to suicide as a protest. Many engage in activism and community support, seeking to address the underlying issues. The prevalence of protest-related suicides in Iran is intricately linked to the country’s political and economic instability. Recent studies indicate a rising trend in suicide attempts, particularly among the youth, which correlates with socio-political unrest and financial hardships. The 2022 protests highlighted the role of political dissatisfaction, with diverse social groups participating, which may contribute to rising despair and suicidal behavior.[6] Economic sanctions and political instability significantly influence suicide rates in Iran, exacerbating existing socio-economic challenges. Economic sanctions have led to increased inflation, unemployment, and poverty, which are strongly correlated with higher suicide rates. While these studies emphasize the detrimental effects of sanctions and instability, it is essential to consider that some regions in Iran have reported a decrease in suicide rates, suggesting that targeted interventions may manage these issues. At the social level, strategies to increase solidarity and social cohesion help to reduce protest suicide. These strategies can include raising awareness, de-stigmatizing, de-discriminating, and creating supportive environments such as self-help networks) in various sectors, including schools, workplaces, and sports clubs. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.
Effect of prolonged exposure to different lighting conditions on MPTP-induced motor dysfunction and cognitive performance in male rats Hamideh Rahmati, Seyedeh Masoumeh Seyedhosseini Tamijani, Hamed Ghazvini, Behzad Garmabi, Ali Siahposht-Khachaki, Saba Niknamfar, Raheleh Rafaiee Chronobiology International, 2025 Circadian rhythm disruption has been increasingly implicated in neurodegenerative diseases, including Parkinson's disease (PD). While motor impairments in PD are well-established, the impact of chronic circadian misalignment on both motor and cognitive dysfunctions remains underexplored. This study investigates the effect of prolonged exposure to different lighting conditions on MPTP-induced motor and cognitive deficits in a rat model. A total of 100 adult male Wistar rats were divided into five groups with different light-dark cycle conditions: standard 12-h light/12-h dark (12 L:12D), constant light (24 L), constant darkness (24D), 20-h light/4-h dark (20 L:4D), and 4-h light/20-h dark (20D:4 L). After 60 d of exposure to these conditions, each group was further divided into Parkinsonian (MPTP-treated) and non-Parkinsonian (saline-treated) subgroups. MPTP hydrochloride (25 µg/kg) was administered intranasally to induce Parkinsonism. Behavioral assessments, including the beam balance test, open field test, Y-maze test, and shuttle box test, were conducted to evaluate motor coordination and cognitive function. Immunohistochemical analyses of α-synuclein (α-syn) accumulation in the substantia nigra (SNc) and tyrosine hydroxylase (TH) expression in the suprachiasmatic nucleus (SCN) were performed. Data were analyzed using t test, one-way ANOVA and Tukey's post hoc test. MPTP administration significantly impaired motor function, as evidenced by increased crossing time in the beam balance test (p < 0.001) and reduced locomotor activity in the open field test (p < 0.01). Prolonged exposure to different lighting conditions further exacerbated these deficits, particularly in the 24 L and 20 L:4D groups (p < 0.0001). Cognitive assessments revealed that MPTP-treated rats exhibited marked deficits in working memory (Y-maze, p < 0.05) and associative learning (shuttle box, p < 0.01), with the most severe impairments observed in groups subjected to extreme light-dark alterations. Immunohistochemical analyses demonstrated significantly increased α-syn accumulation in the SNc (p < 0.0001) and decreased TH expression in the SCN (p < 0.001), particularly in MPTP-treated rats under photoperiod disruption. Chronic photoperiod disruption exacerbates MPTP-induced motor dysfunction, cognitive impairment, and neurodegeneration. Targeting circadian regulation may offer a potential therapeutic approach for mitigating neurodegenerative progression in PD.
Coenzyme Q10 ameliorates anxiety and depression-like behavior associated with chronic opioid use and increases GDNF expression in the hippocampus of morphine-dependent rats Mobina Gheibi, Somayeh Nazari, Fahimeh Mohseni, Pooria Salehi Sangani, Farzaneh Felehkari, Saba Niknamfar, Hamed Ghazvini, Seyedeh Masoumeh Seyedhosseini Tamijani, Hamid Kalalian-moghaddam, Hamid Jomehpour, Raheleh Rafaiee Acta Neurobiologiae Experimentalis, 2025 Opioid dependence is strongly associated with moderate to severe depression and anxiety. The primary objective of this investigation was to determine whether coenzyme Q10 (CoQ10) has the capacity to increase the level of glial cell line‑derived neurotrophic factor (GDNF), with the aim of ameliorating anxiety‑ and depression‑like behaviors in morphine (MOP)‑dependent rats. In this study, 40 male Wistar rats were randomly divided into five experimental groups: Oil group, MOP+Oil group, MOP+Q10‑100 group, MOP+Q10‑200 group, and MOP+Q10‑400 group. Rats received escalating doses of MOP (25 to 100 mg/kg, s.c.) once daily. After 21 days of drug dependency, CoQ10 was administered orally at doses of 100, 200, and 400 mg/kg once daily for four weeks. Behavioral assessments were conducted using the open field test, elevated plus maze, and forced swim test. GDNF expression in the hippocampus was evaluated using immunohistochemistry. Four weeks of CoQ10 treatment significantly improved anxiety‑ and depression‑like behaviors induced by MOP administration. Furthermore, CoQ10 significantly increased GDNF expression in the hippocampus. Oral administration of CoQ10 at doses of 100, 200, and 400 mg/kg over four weeks significantly reduced depressive‑ and anxiety‑related behaviors associated with prolonged MOP exposure. These behavioral improvements were accompanied by increased hippocampal GDNF expression.
Six-Year Survival With Pharmacological Management in a Patient With Aneurysmal Aortic Dissection and Severe Heart Failure: A Case Report Iranian Heart Journal, 2025
The Effects of Testosterone on Cognitive Function Impairments and Brain Edema Induced by Methamphetamine in Gonadectomized Rats Journal of Mazandaran University of Medical Sciences, 2024
The effect of Intraventricular Injection of Kisspeptin-13 on Social Memory Deficits Induced by Methamphetamine Administration in Male Rats Journal of Mazandaran University of Medical Sciences, 2024
Animal Models of Addiction: A Review Hamed Ghazvini, Department of Neuroscience, Faculty of Advanced Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran, Seyedeh Masoumeh Seyedhoseini Tamijani, Psychiatry, Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran, Raheleh Rafaiee, Department of Neuroscience, Faculty of Advanced Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran Neuroscience Journal of Shefaye Khatam, 2022
Effects of estrogen and progesterone on behavioral impairment and neuronal death in ovariectomized rats induced by methamphetamine Journal of Mazandaran University of Medical Sciences, 2020
Ethical Issues in Sex Based Animal Research: Sex Based Exclusion and Euthanasia of Female Laboratory Animals as an Ethical Concern F Mohseni, R Rafaiee Journal of Applied Animal Ethics Research 1 (aop), 1-5 , 2026 2026
Involvement of CB1 cannabinoid receptors in methamphetamine-related decision-making and social behavior deficits T Mousavi, N Hatami, S Niknamfar, M Naseri, R Rafaiee, SMS Tamijani, ... BMC neuroscience , 2026 2026
Coenzyme Q10 Mitigates Anxiety-and Depression-Like Behaviors in a Fetal Alcohol Spectrum Disorder Model by Suppressing Hippocampal Astrocytic Reactivity, Oxidative Stress, and … R Adabi, F Mohseni, A Masoudi, R Rafaiee Journal of Studies on Alcohol and Drugs, jsad. 25-00290 , 2026 2026
Preclinical evidence for statin modulation of analgesic tolerance and substance use disorders: a narrative review MS Ranaiy, SM Seyedhosseini Tamijani, H Ghazvini, ... The American Journal of Drug and Alcohol Abuse, 1-16 , 2026 2026
Neuroprotective Effect of Rutin on Neurobehavioral Dysfunction and Cognitive Impairment-Induced by Methamphetamine in Male Rats M Gheibi, S Nazari, M Vahabzadeh-Kebria, PS Sangani, E Beirami, ... IJ Psychiatry and Behavioral Sciences 19 (1), e150376 , 2025 2025
Brain Tumor Presenting Mania Symptoms: A Case Report SH Hosseini, H Ghazvini, SMS Tamijani, R Rafaiee Acta Medica Iranica 63 (4), 264-266 , 2025 2025
Pregabalin misuse: a case report SH Hosseini, H Ghazvini, SM Seyedhosseini Tamijani, R Rafaiee Journal of Substance Use 30 (6), 1019-1022 , 2025 2025 Citations: 1
Neuroprotective Effects of Erythropoietin in Fetal Alcohol Spectrum Disorder: BDNF Upregulation, Reduced Astrogliosis, and Anxiety Relief R Rafaiee, F Mohseni Journal of Studies on Alcohol and Drugs 86 (6), 917-927 , 2025 2025
Quantitative Electroencephalographic Biomarkers for Repetitive Transcranial Magnetic Stimulation Treatment Response Prediction in Mild Cognitive Impairment: A Pilot Study … Z Yousefian, SH Hosseini, MA Nazari, R Kazemi, M Asghari‐Jafarabadi, ... Brain and Behavior 15 (11), e71017 , 2025 2025
Pulmonary complications of substance abuse: pathophysiology, diagnosis, and management strategies F Shahi, R Rafaiee, N Keikhaei, SHA Tahergourabi, H Jomehpour, ... Addiction & Health 17, 1641 , 2025 2025 Citations: 1
Protest-related Suicide against Socio-political Conditions R Rafaiee, F Mohseni Indian Journal of Social Psychiatry 41 (4), 450-451 , 2025 2025
Treatment-resistant Nausea and Vomiting: A Challenge in Clinical Practice R Rafaiee, R Rafaiee, A Bakhshipour Middle East Journal of Digestive Diseases (MEJDD) 17 (3), 233-235 , 2025 2025
Reflection of New Drug Policy: Changing Drug Consumption Patterns and its Challenges H Jomehpour, MN Sarvandani, R Rafaiee Iranian Journal of Public Health 54 (8), 1803-1804 , 2025 2025
Urinary Incontinence During Sleep Associated With Buspirone: A Case Report. SH Hosseini, H Ghazvini, SMS Tamijani, R Rafaiee Pharmaceutical & Biomedical Research 11 (3) , 2025 2025
Circadian rhythms and human studies: methodology, challenges, and future directions in research H Rahmati, B Garmabi, H Ghazvini, SM Seyedhosseini Tamijani, ... Biological Rhythm Research 57 (2), 71-100 , 2025 2025 Citations: 1
CB1 receptor antagonism reverses social and cognitive deficits induced by repeated exposure to distressed conspecifics in rats FR Shourmasti, SMS Tamijani, R Rafaiee, M Khodamoradi, M Shabani, ... Neuroscience Letters 863, 138299 , 2025 2025 Citations: 1
Effect of prolonged exposure to different lighting conditions on MPTP-induced motor dysfunction and cognitive performance in male rats H Rahmati, SM Seyedhosseini Tamijani, H Ghazvini, B Garmabi, ... Chronobiology International 42 (8), 1080-1095 , 2025 2025
Substance Use Disorders and Suicidal Behaviors: Comparison of Illicit Drugs and Methadone H Jomehpour, F Mohseni, R Rafaiee Iranian Journal of Psychiatry and Clinical Psychology 31 (1) , 2025 2025 Citations: 1
Six-Year Survival With Pharmacological Management in a Patient With Aneurysmal Aortic Dissection and Severe Heart Failure: A Case Report F Mohseni, R Rafaiee, M Yousefi, H Sheibani Iranian Heart Journal 26 (3), 83-91 , 2025 2025
Modulatory Effects of CB1 Receptors on Cognitive Performance in Rat Model of Empathic Pain F Rahimi Shourmasti, R Rafaiee, SM Seyedhosseini Tamijani, ... Basic and Clinical Neuroscience 16 (4), 715-726 , 2025 2025
MOST CITED SCHOLAR PUBLICATIONS
The Relationship Between the Type of Crime and Drugs in Addicted Prisoners in Zahedan Central Prison R Rafaiee, S Olyaee, A Sargolzaiee International Journal of High Risk Behaviors and Addiction 2 (3) , 2013 2013 Citations: 49
Role of the cannabinoid CB1 receptor in methamphetamine-induced social and recognition memory impairment M Khodamoradi, F Tirgar, H Ghazvini, R Rafaiee, SMS Tamijani, N Karimi, ... Neuroscience letters 779, 136634 , 2022 2022 Citations: 34
Ovarian hormones prevent methamphetamine-induced anxiety-related behaviors and neuronal damage in ovariectomized rats H Ghazvini, F Tirgar, M Khodamoradi, Z Akbarnejad, R Rafaiee, ... Neuroscience Letters 746, 135652 , 2021 2021 Citations: 33
Effects of berberine hydrochloride on methamphetamine-induced anxiety behaviors and relapse in rats L Rezaeian, H Kalalian-Moghaddam, F Mohseni, M Khaksari, R Rafaiee Iranian journal of basic medical sciences 23 (11), 1480 , 2020 2020 Citations: 29
Analysis of Gap in Service Quality in Drug Addiction Treatment Centers of Kerman, Iran, Using SERVQUAL Model MR Naqavi, R Refaiee, MR Baneshi, N Nakhaee Addiction and Health 6 (3) , 2014 2014 Citations: 27
Lapse and Relapse Rates in Narcotics Anonymous versus Methadone Maintenance Treatment: A 12-Month Prospective Study F Mohseni, K Rahimi, M Niroumand Sarvandani, Z Jamali, ... Iranian Journal of Psychiatry 17 (1), 1-13 , 2022 2022 Citations: 24
Chronotype patterns associated with job satisfaction of shift working healthcare providers F Amini, SM Mousavi, R Rafaiee, AA Nadi Ghara, M Babakhnian Chronobiology international 38 (4) , 2021 2021 Citations: 24
A review of the historical evolutionary process of dry and water maze tests in rodents F Mohseni, SG Behnam, R Rafaiee Basic and Clinical Neuroscience 11 (4), 389 , 2020 2020 Citations: 24
COVID-19 and the Brain: A Psychological and Restingstate Functional Magnetic Resonance Imaging (fMRI) Study of the Whole-brain Functional Connectivity. MN Sarvandani, JS Koohsar, R Rafaiee, M Saeedi, SMS Tamijani, ... Basic & Clinical Neuroscience 14 (6) , 2023 2023 Citations: 23
Apelin 13 Improves Anxiety and Cognition Via Hippocampal Increases BDNF Expression and Reduction Cell Death in Neonatal Alcohol Exposed Rats F Mohseni, M Khaksari, R Rafaiee, K Rahimi, P Nourouzi, B Garmabi Iinternational Journal of Peptide Research and Therapeutics 27, 1351-1362 , 2021 2021 Citations: 23
The Effectiveness of Mindfulness-based Stress Reduction (MBSR) Treatment on Anxiety, Depression and Prevention of Substance Use Relapse M Niroumand Sarvandani, N Khezri Moghadam, H Kalalian Moghadam, ... International Journal of Health Studies 7 (2) , 2021 2021 Citations: 22
Hydrogen sulfide protects hippocampal CA1 neurons against lead mediated neuronal damage via reduction oxidative stress in male rats R Rafaiee, H Khastar, B Garmabi, M Taleb, P Norouzi, M Khaksari Journal of Chemical Neuroanatomy 112, 101917 , 2021 2021 Citations: 22
Hydrogen sulfide improves spatial memory impairment via increases of BDNF expression and hippocampal neurogenesis following early postnatal alcohol exposure F Mohseni, F Bagheri, R Rafaiee, P Norozi, M Khaksari Physiology & behavior 215, 112784 , 2020 2020 Citations: 22
Neuroprotective effects of berberine hydrochloride on methamphetamine-induced cognitive dysfunction: immunohistochemical and behavioral studies in rats L Rezaeian, M Khaksari, R Rafaiee, HK Moghaddam Basic and Clinical Neuroscience 13 (4), 443 , 2022 2022 Citations: 20
Effects of estrogen and progesterone on behavioral impairment and neuronal death in ovariectomized rats induced by methamphetamine H Ghalehnoei, H Ghazvini, A Mellati, SM Seyedhosseini Tamijani, ... Journal of Mazandaran University of Medical Sciences 30 (186), 1-12 , 2020 2020 Citations: 17
Increased Suicide of Iranian Resident Physicians in the COVID-19 Pandemic S Nazari, H Ghazvini, S Seyedhisseini T., R Rafaiee International journal of high risk behavior and addiction 11 (1), e117651 , 2022 2022 Citations: 12
Opium syrup distribution, limitation and challenges M Dahmardehei, R Rafaiee Zahedan J Res Med Sci 14 (6), 48 , 2012 2012 Citations: 12
Berberine hydrochloride improves cognitive deficiency through hippocampal up-regulation of neurotrophins following inhalant self-administration of methamphetamine F Mohseni, R Rafaiee, L Rezaeian, M MNiroumand Sarvandani, ... Iranian Journal of Basic Medical Sciences 26, 1-7 , 2023 2023 Citations: 11
Bone Marrow Mesenchymal Stem Cells Improve Cognitive Impairments Induced by Methamphetamine in Rats and Reduce Relapse R Rafaiee, N Ahmadiankia, SA Mousavi, B Jafari, HK Moghaddam bioimpacts, 10-15 , 2022 2022 Citations: 11
Prevalence of Child Abuse and Correlations with Family Factors Among Elementary School-aged Children R Rafaiee, F Mohseni, N Akbarian International Journal of High Risk Behaviors and Addiction 10 (2), e108823 , 2021 2021 Citations: 11