MOST CITED SCHOLAR PUBLICATIONS
- Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.T Shirasaka, MF Kavlick, T Ueno, WY Gao, E Kojima, ML Alcaide, ...Proceedings of the National Academy of Sciences 92 (6), 2398-2402 1995Citations: 485
- Changes in drug sensitivity of human immunodeficiency virus type 1 during therapy with azidothymidine, dideoxycytidine, and dideoxyinosine: an in vitro comparative study.T Shirasaka, R Yarchoan, MC O'Brien, RN Husson, BD Anderson, ...Proceedings of the National Academy of Sciences 90 (2), 562-566 1993Citations: 167
- Genotypic and phenotypic characterization of HIV-1 isolated from patients receiving (−)-2′, 3′-dideoxy-3′-thiacytidineMF Kavlick, T Shirasaka, E Kojima, JM Pluda, F Hui Jr, R Yarchoan, ...Antiviral Research 28 (2), 133-146 1995Citations: 104
- Vertical transmission of human immunodeficiency virus type 1: autologous neutralizing antibody, virus load, and virus phenotypeRN Husson, Y Lan, E Kojima, D Venzon, H Mitsuya, K McIntoshThe Journal of pediatrics 126 (6), 865-871 1995Citations: 71
- Lipophilic halogenated congeners of 2', 3'-dideoxypurine nucleosides active against human immunodeficiency virus in vitro.T Shirasaka, K Murakami, H Ford Jr, JA Kelley, H Yoshioka, E Kojima, ...Proceedings of the National Academy of Sciences 87 (23), 9426-9430 1990Citations: 68
- Escherichia coli mediated biosynthesis and in vitro anti-HIV activity of lipophilic 6-halo-2', 3'-dideoxypurine nucleosidesK Murakami, T Shirasaka, H Yoshioka, E Kojima, S Aoki, H Ford Jr, ...Journal of medicinal chemistry 34 (5), 1606-1612 1991Citations: 53
- Diastereo-and enantioselective reduction of α, β-diketodithiane with the baker's yeastT Fujisawa, E Kojima, T Itoh, T SatoTetrahedron letters 26 (49), 6089-6092 1985Citations: 53
- NP-06: a novel anti-human immunodeficiency virus polypeptide produced by a Streptomyces speciesS Chokekijchai, E Kojima, S Anderson, M Nomizu, M Tanaka, M Machida, ...Antimicrobial agents and chemotherapy 39 (10), 2345-2347 1995Citations: 44
- 2', 3'-dideoxy purine nucleosideE Kojima, H Yoshioka, H Fukinbara, K MurakamiUS Patent 5,053,499 1991Citations: 43
- Human Immunodeficiency Virus Type 1 (HIV-l) Viremia Changes and Development of Drug-Related Mutations in Patients with Symptomatic HIV-l Infection Receiving Alternating orE Kojima, T Shirasaka, BD Anderson, S Chokekijchai, SM Steinberg, ...Journal of Infectious Diseases 171 (5), 1152-1158 1995Citations: 39
- A C2 Symmetry-Based HIV Protease Inhibitor, A77003, Irreversibly Inhibits Infectivity of HIV-1 In VitroS KAGEYAMA, DT HOEKZEMA, Y MURAKAWA, E KOJIMA, ...AIDS research and human retroviruses 10 (6), 735-743 1994Citations: 33
- 2', 3'-dideoxy purine nucleosides and process for the preparation thereofE Kojima, H Yoshioka, H Fukinbara, K MurakamiUS Patent 5,563,049 1996Citations: 25
- Monitoring the activity of antiviral therapy for HIV infection using a polymerase chain reaction method coupled with reverse transcriptionE Kojima, T Shirasaka, B Anderson, S Chokekijchai, S Sei, R Yarchoan, ...AIDS 7, S101-106 1993Citations: 24
- (2S,3S)-1-Phenylthio-2,3-butanediol. A Useful Chiral Building Block for a Simple Syntheses of (4R,5S)-5-Hydroxyhexan-4-olide and (4R,5S)-5-Hydroxy-2T Fujisawa, E Kojima, T SatoChemistry Letters 16 (11), 2227-2228 1987Citations: 19
- Emergence of HIV-1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosidesT Shirasaka, M Kavlick, T Ueno, WY Gao, E Kojima, ML Alcaide, ...Proc Natl Acad Sci USA 92 (2398), 402 1995Citations: 12
- Identification of drug-related genotypic changes in HIV-1 from serum using the selective polymerase chain reactionBD Anderson, T Shirasaka, E Kojima, R Yarchoan, H MitsuyaAntiviral research 25 (3-4), 245-258 1994Citations: 9
- Lipophilic 6-halo-2′, 3′-dideoxypurine nucleosides: potential antiretroviral agents targeting HIV-associated neurologic disordersT Shirasaka, K Watanabe, H Yoshioka, E Kojima, S Aoki, K Murakami, ...Advances in molecular biology and targeted treatment for AIDS, 323-333 1991Citations: 9
- ENANTIOSELECTIVE SYNTHESIS OF α-HYDROXYTHIOACETALS BY THE BAKER’S YEAST REDUCTION OF α-KETOTHIOACETALST Fujisawa, E Kojima, T Itoh, T SatoChemistry letters 14 (11), 1751-1754 1985Citations: 8
- Antiviral effects of 6-chloro-2', 3'-dideoxyguanosine in rhesus monkeys acutely infected with simian immunodeficiency virus.Y Fujii, R Mukai, H Akari, M Machida, K Mori, M Takasaka, E Kojima, ...Antiviral chemistry & chemotherapy 9 (1), 85-92 1998Citations: 7
- Efficacy of 6-chloro-2', 3'-dideoxyguanosine (6-Cl-ddG) on rhesus macaque monkeys chronically infected with simian immunodeficiency virus (SIVmac239)Y Fujii, R Mukai, K Mori, H Akari, I Otani, F Ono, E Kojima, M Takasaka, ...JAIDS Journal of Acquired Immune Deficiency Syndromes 16 (5), 313-317 1997Citations: 7
