Gaetano Burriesci

Scopus Publications

In silico analysis of the haemodynamic disturbances caused by the subaortic membrane pathology
Alessandra Monteleone, Gaetano Burriesci
Computers in Biology and Medicine, 2026
Critical analysis of strain measurement approaches in tensile testing of nitinol
Valentina Pinto, Sofia Di Leonardo, Giuseppe Pitarresi, Gaetano Burriesci
Proceedings of the Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science, 2026
Nitinol superelasticity is a crucial property for collapsible/expandable cardiovascular implants. The high class of risk associated with these devices requires an accurate mechanical characterisation as starting point for a reliable design methodology. Actual standards (ASTM-F2516) are based on standard metal testing and recommend the use of extensometers for the measurement of average nominal strains during tensile tests. However, measurement provided by classic extensometers may not be adequate to capture the strain evolution during the material phase transformation. These limitations can be overcome by full-field optical techniques such as Digital Image Correlation (DIC). This work presents a comprehensive comparison of various techniques for measuring strain on nitinol specimens. These include crosshead position, single and averaging (applied on both sides of the specimen) measurements using physical extensometers, virtual extensometer, and 1D and 2D DIC. Results are compared on the basis of the values determined for the upper/lower plateau stress, as defined by ASTM-F2516. Results show that the use of extensometers on nitinol strips subjected to tensile testing is inaccurate during phase transformation. Physical extensometers also introduce spurious local concentrated pressures at the knives contact region, which may alter the material stress plateaus values. DIC resulted more adequate to provide an accurate evaluation of strain localisation.
An advanced immersed fluid–structure interaction particle method for cardiovascular applications experimentally validated vs a new benchmark case
Alessandra Monteleone, Sofia Di Leonardo, Marco Correnti, Enrico Napoli, Giorgio Micale, et al.
Physics of Fluids, 2026
Fluid–structure interaction (FSI) is crucial in the numerical simulation of cardiovascular phenomena, where pulsatile blood flow dynamically interacts with highly deformable tissues. High-fidelity FSI approaches have become essential to enhance the understanding of potentially lethal pathologies, assisting diagnosis and development of novel therapeutic solutions. This work presents and experimentally validates a new, totally meshless FSI approach, specifically designed for cardiovascular applications. The method is based on the Lagrangian smoothed particle hydrodynamics (SPH), employing a unified physics to represent both blood and deformable walls, avoiding FSI interfaces. A key advantage of this method lies in its ability to overcome the SPH complex issue in contour management, a common challenge that typically increases the complexity of this methodology in FSI applications. Deformable walls are immersed in the fluid domain, and a buffer region of fluid is defined to handle the structural deformation. For validation, a new FSI benchmark is proposed and analyzed with the particle image velocimetry technique. Tailored to entail the typical complexities of relevant cardiovascular situations, the benchmark involves pulsatile flow interacting with a chamber with deformable curved walls, moving through both filling and emptying phases. Despite its simplified geometry, designed to allow a reliable experimental validation, the structure experiences a field of three-dimensional strains and large volume variations, thereby replicating complexities often associated with more intricate models. Numerical and experimental results show good agreement in terms of fluid velocity field and structural deformation, establishing the proposed totally meshless FSI approach as a reliable tool for complex cardiovascular modeling.
Artificial Muscles for Footwear Technology: Knitting Structures With Variable Elasticity
Advances in Materials Science and Engineering, 2026
An Innovative One-Step Method to Produce Membranes with a Pore Size Gradient
Chemical Engineering Transactions, 2026
The use of human decellularized amniotic membrane as pulmonary valve leaflets in right ventricular outflow tract reconstruction – an in vivo proof of concept study
Mohamed T. Ghorbel, Tasneem Salih, Giulia Parolari, Katie L. Skeffington, Sofia Di Leonardo, et al.
Frontiers in Bioengineering and Biotechnology, 2026
Introduction Despite fundamental improvements in surgical treatment of Congenital Heart Defects, there are still challenges related to premature failure of the material used for such corrections, thus resulting in repeated operations during a patient’s life. This is particularly the case for complex defects with Right Ventricular Outflow Tract (RVOT) obstruction, such as in Tetralogy of Fallot/Pulmonary Atresia, whereby the pulmonary valve reconstruction remains problematic due to short-term durability of the currently used replacement solutions. We set out to test, for the first time, the suitability of amniotic membrane derived from human placenta for use in cardiovascular replacement of pulmonary valve. Methods The decellularized and preserved amniotic membrane, obtained through our optimised protocol, was characterised for mechanical and hydrodynamic properties in vitro , and then implanted in the RVOT position of two Landrace piglets for in vivo feasibility and performance evaluation. Results Both the in vitro and in vivo assessments showed favourable outcomes. The decellularized amniotic membrane had mechanical properties comparable to the native porcine pulmonary valve leaflets. In hydrodynamic testing, the decellularized amniotic membrane-made valve exhibited favourable opening dynamics, with smooth and coordinated leaflet motion throughout the cycle. In vivo , the decellularized amniotic membrane-based valved conduit showed patency in the short- and long-term with no sign of stenosis or regurgitation. Discussion This study provides an in vivo proof of concept that the decellularized amniotic membrane can be implanted and perform as functional pulmonary valve in a porcine animal model mimicking the clinical scenario of Tetralogy of Fallot surgical correction in infants.
Inversion of the thermomechanical response in nitinol under cyclic loading: an analytical interpretation based on the thermoelastic effect theory
V. Pinto, S. Di Leonardo, G. Pitarresi, G. Burriesci
Mechanics of Materials, 2025
Erratum: Author Correction: Valvulogenesis of a living, innervated pulmonary root induced by an acellular scaffold (Communications biology (2023) 6 1 DOI: 10.1038/s42003-023-05383-z.)
Magdi H. Yacoub, Yuan-Tsan Tseng, Jolanda Kluin, Annemijn Vis, Ulrich Stock, et al.
Communications Biology, 2025
Retrokinetics of crystallization
Luke Hunter, Ryo Torii, Gaetano Burriesci, Sergio Bertazzo
Scripta Materialia, 2025
Hydrodynamic Alterations Produced by Subaortic Membranes: An in Vitro Study
Sofia Di Leonardo, Danila Vella, Calogera Pisano, Vincenzo Argano, Gaetano Burriesci
Irbm, 2025
Evaluation of NiTi under low-amplitude cyclic loading by means of thermographic harmonic analysis
V. Pinto, R. Cappello, S. Di Leonardo, G. Catalanotti, G. Burriesci, et al.
Mechanics of Materials, 2025
Double-loop suture repair of radial meniscal tears provides favourable biomechanical performance compared to conventional repair techniques: A biomechanical study
Antonio Petillo, Alessandro Di Rosa, Carmelo Burgio, Sofia Di Leonardo, Gaetano Burriesci, et al.
Journal of Experimental Orthopaedics, 2025
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation
Anna Maria Lo Presti, Alessandra Monteleone, Giulio Musotto, Alessandro Tamburini, Enrico Napoli, et al.
Computers in Biology and Medicine, 2025
A new braided model of the Amulet Amplatzer for accurate simulations of left atrial appendage occlusion procedures
Rafizul Islam Md, Matthew T. Lee, Andrew C. Cook, Jonathan Weir-McCall, Claire A. Martin, et al.
Computers in Biology and Medicine, 2025
In Vitro Evaluation of Biomaterials for Heart Valve Prosthesis: High Hydrostatic and Enzymatic Treatments as Alternative for Bio-Derived Materials
Danila Vella, Parnaz Boodagh, Laura Modica De Mohac, Sang‐Ho Ye, Federica Cosentino, et al.
Journal of Biomedical Materials Research Part B Applied Biomaterials, 2025
Whitlockite can be a substrate for apatite growth in simulated body fluid
Luke Hunter, Ryo Torii, Gaetano Burriesci, Sergio Bertazzo
Materialia, 2025
Effect of nanocomposite chitosan/hydroxyapatite pH-induced hydrogels on the osteogenic differentiation of spheroids from adipose stem cells
A.B. Di Stefano, C. Di Marco, F. Toia, M. Trapani, M. Testa, et al.
International Journal of Biological Macromolecules, 2025
Analysis of the haemodynamic changes caused by surgical and transcatheter aortic valve replacements by means fluid-structure interaction simulations
Anna Maria Tango, Alessandra Monteleone, Andrea Ducci, Gaetano Burriesci
Computers in Biology and Medicine, 2025
Photooxidation Cross-Linked, Glutaraldehyde Cross-Linked, or Enzyme and Hydrostatic Pressure Processed Decellularized Biomaterials for Cardiovascular Repair Do Not Affect Host Response in a Rat Right Ventricular Outflow Flow Tract Reconstruction (RVOT) Model
Parnaz Boodagh, Laura Modica De Mohac, Yasurani Hayashi, Danila Vella, Sang‐Ho Ye, et al.
Journal of Biomedical Materials Research Part B Applied Biomaterials, 2025
Synchronous Inflation of a Valvuloplasty Balloon Catheter with Heart Rate: In-Vitro Evaluation in Terms of Dilatation Performance
Junke Yao, Xinyi Pi, Giorgia Maria Bosi, Gaetano Burriesci, Helge Wurdemann
IEEE Robotics and Automation Letters, 2025
Impact of trabeculae on thromboembolic risk in the left atrial appendage
Convegno Nazionale Di Bioingegneria, 2025
Fabrication and Validation of a dual stimulation Organ-on-Chip
Convegno Nazionale Di Bioingegneria, 2025
Personalized Stroke Risk Assessment in Atrial Fibrillation Using FluidStructure Interaction and Deep Learning
Giulio Musotto, Danila Vella, Alessandra Monteleone, Nicolina Sciaraffa, Claudia Coronnello, et al.
Proceedings of the World Congress on Electrical Engineering and Computer Systems and Science, 2025
Development and Characterization of a Blood-Mimicking Fluid for Hemodynamic Research
Convegno Nazionale Di Bioingegneria, 2025
Rheological and morphological insights into Bio-glass 1393 and Car12N incorporation in PLLA and Chitosan scaffolds
Convegno Nazionale Di Bioingegneria, 2025