Firas Khaleyla

@unesa.ac.id

Faculty of Mathematics and Natural Sciences
Universitas Negeri Surabaya

EDUCATION

Master of Science in Biology

RESEARCH INTERESTS

Animal Physiology
Cell Biology
19

Scopus Publications

376

Scholar Citations

10

Scholar h-index

10

Scholar i10-index

Scopus Publications

  • HOTS-based science questions as assessment instrument for elementary school students: Examining validity and reliability
    Endang Susantini, Julianto, Maryam Isnaini Damayanti, Firas Khaleyla, Mi’rojul Huda
    International Journal of Education and Practice, 2026
    Assessments based on Higher-order Thinking Skills (HOTS) are critical for elementary students as they are important; however, standardized tools are still lacking. Hence, this study aims to develop valid and reliable HOTS-based science questions as assessment instruments to measure elementary school students’ mastery of science subjects and HOTS. This study employed the Design and Development Research (DDR) model to create HOTS-based science questions for grades four, five, and six at the elementary level. The research involved analysis, design, development, and evaluation phases to produce six summative science questions for each grade. Qualitative data were obtained through focus group discussions (FGD) to align with curriculum analysis. Quantitative data were collected via validation sheets and trial tests to assess validity and reliability. The results indicate that there are two science topics with three HOTS-based instructional objectives for each grade. These instructional objectives were developed using three question types: multiple-choice questions (MCQs) with four options, complex MCQs, and essay questions. MCQs were used to evaluate students’ analytical skills, complex MCQs to assess evaluative skills, and essay questions to measure creative skills and metacognitive knowledge. The developed HOTS-based science questions were deemed valid (CVR = +0.73, CVI = +1.00) and reliable (ICC = 0.914, Cronbach’s α > 0.80). This study suggests that the developed HOTS-based science questions can be utilized by elementary science teachers to assess students’ mastery of science subjects and HOTS.
  • Morphological and Molecular Characterization of Pufferfish from Lekok Coastal Area, Pasuruan Indonesia
    Viona Angelina Erlan Panjaitan, Adam Dwi Rangga, Cahya Ajeng Valenta Tresna Sulung, Dwi Anggorowati Rahayu, Firas Khaleyla, Endik Deni Nugroho, Rusdianto Rusdianto, Noorhidayah Binti Mamat
    Biosaintifika, 2025
    Pufferfish belong to the Tetraodontidae family, which consists of 28 genera and 184 species; however, there are limited studies on the species from East Java, especially Pasuruan. This indicates the need for the collection of more accurate morphological and genetic resources as an important step for its conservation. Therefore, this study was conducted to identify pufferfish species found in the Lekok Coastal Waters, Pasuruan District, through morphological characterization and molecular analysis using DNA barcoding of the COI gene. A total of 12 samples were collected from the Lekok Coastal Waters, Pasuruan Regency. Fin samples were stored in 96% absolute ethanol. DNA extraction, polymerase chain reaction (PCR), and sequence analysis were performed using bioinformatics tools, the BOLD system, and the Automatic Barcode Gap Discovery (ABGD) web platform. Phenetic taxonomy was further applied using Ntysc to enhance the robustness of genetic analysis. The results showed that there were identified five pufferfish species were identified: Lagocephalus spadiceus, Chelonodontops patoca, Cyclichthys orbicularis, Arothron stellatus, and Arothron reticularis. High haplotype diversity (Hd) of 1 and nucleotide diversity (π) of 0.1 indicate significant genetic variation. The frequency of parsimonious informative sites was 22.6%, with 13 polymorphic sites and an overall ts/tv ratio of 2.2. The phylogenetic tree showed unambiguous branching patterns among species. These findings are supported by morphological and molecular identification results, which indicate the presence of five species of pufferfish along the Lekok Coast, Pasuruan Regency.
  • Organization, density, and content of collagen in the body wall of sea cucumbers Acaudina rosettis and Phyllophorus sp.
    Nithasya Nabilla, Imarotus Shofiyah, Sugiharto, Dita Alvitasari, Sri Sumarsih, Firas Khaleyla, Ismiliana Wirawati, Dwi Winarni
    Aquaculture and Fisheries, 2025
    Marine collagen has been known to have lower immunogenicity compared to bovine collagen. The primary component in the body wall of sea cucumbers is collagen. This study aimed to investigate the density, bundle organization, and yield of collagen in the two sea cucumber species, Acaudina rosettis and Phyllophorus sp. collected from the Madura Strait, Indonesia. The body wall parts, including the dorsal anterior, dorsal median, dorsal posterior, ventral anterior, ventral median, and ventral posterior, from five samples of each species, were fixed and decalcified. They were histologically processed using the paraffin method before staining them with Van Gieson to visualize collagen in the cross-sections of body wall tissue. Collagen density was determined using the ImageJ software, while collagen bundle organization was examined negatively by utilizing the image editing application. Collagen density data were analyzed using repeated-measures ANOVA (α = 0.05). Collagen content in the body wall of each species was examined using acid solubilization-based collagen extraction, which did not significantly differ between different parts of the body wall in each species (p = 0.161 for A. rosettis , p = 0.095 for Phyllophorus sp.). However, Phyllophorus sp. exhibited a higher collagen density and collagen bundles, which were larger and more organized compared to A . rosettis . The collagen content was higher in A . rosettis (10.07%) compared to Phyllophorus sp. (8.07%). Further study can be performed to explore the potential of collagen from these sea cucumber species for commercial use.
  • Research trend of bivalves aquaculture in Southeast Asia during two decades based on bibliometric analysis in supporting 14th SDG
    Reni Ambarwati, Muhammad Z. Afnan, Agung L. Fauzan, F.A. Agum Pratama, Ahnadia W. Ramadhana, Isnawati, Firas Khaleyla, Muhammad Ar Rozzaaq Nugraha
    E3s Web of Conferences, 2025
    Southeast Asia, including Indonesia, is the center of the world’s marine biodiversity, especially for bivalve groups such as oysters, mussels, clams, and cockles. This group has high economic value, both as a consumption commodity and industrial raw material. This study analyses trends of research and focused species in bivalve aquaculture research in Southeast Asia during 2005–2025 using a bibliometric approach. From 3,209 initial articles, 75 relevant articles were analyzed using the VOSviewer and Biblioshiny tools. The results show that research focuses on issues of microplastic pollution, genetic variation, growth rate, and environmental monitoring. Publications are dominated by the Philippines and Vietnam, while Indonesia’s scientific contribution is still low despite its great potential. The most frequent studied species are Perna viridis and Tegillarca granosa. This reveals that there are still great opportunities in bivalve’s aquaculture research in supporting the 14th SDG, “Life below water”.
  • Global trend of STEM Education for the SDGs of the last decade: A bibliometric analysis
    Muhammad Jakfar, Utama Alan Deta, Nurita Apridiana Lestari, Firas Khaleyla, Ratih Dewi Saputri, Achmad Arrosyidi
    E3s Web of Conferences, 2024
    STEM (Science, Technology, Engineering, and Mathematics) can help achieve the Sustainable Development Goals (SDGs) by fostering the development of 21st-century skills. It sparked a significant advancement in research on science education within the STEM field. This research intends to explore trends in STEM education for the SDGs by conducting a bibliometric analysis using the extensive Scopus databases. A total of 58 papers were reviewed from Scopus databases. A descriptive study method was employed to analyze the data. This study found that the number of STEM education and SDGs programs has increased over the past decade (2013-2023). The most prolific authors according to Scopus are seven authors. Over the past decade, Sustainability Switzerland has been the most significant source of documents on STEM education and SDGs. The VosViewer showcases six clusters associated with STEM Education and SDGs: Sustainable development goal, engineering education, science technology, quality education, stem education, and physics.
  • Renoprotective effects of Cermai Leaves (Phyllanthus acidus (L.) Skeels) as a candidate for antidiabetic in silico
    Erlix Rakhmad Purnama, Nur Kuswanti, Nur Qomariyah, Firas Khaleyla, R. Ahmad Zainul Aziz
    E3s Web of Conferences, 2024
    Renal complications are a major concern in individuals with diabetes, necessitating the search for effective antidiabetic agents with renoprotective properties. Phyllanthus acidus (L.) Skeels, commonly known as Cermai leaves, have been recognized for their medicinal properties, including potential antidiabetic effects. This in silico study aimed to investigate the renoprotective effects of Phyllanthus acidus as an antidiabetic agent by targeting the insulin-like growth factor-1 (IGF-1) (PDB code 1GZR) and angiotensin-converting enzyme 2 (ACE2) (PDB code 6M0J) receptors. The prediction of phytochemical properties was made based on the five laws of Lipinski as seen from the values of absorption, distribution, and metabolism with Swiss ADME. The in-silico method was conducted with the assistance of computer devices, databases like Protein Data Bank (PDB) and PubChem, and software like PyRx and Discovery Studio. The results showed the compounds kaempferol and cafestol meet the five laws of Lipinski. The compound kaempferol has the lowest binding affinity, with a value of -5.8 kcal/mol on IGF-1 and -6.1 kcal/mol on ACE2 and cafestol, -5.6 kcal/mol on IGF-1 and -5.8 kcal/mol on ACE2. It’s compared to the native ligand value -3.9 kcal/mol on IGF-1 and -5.2 kcal/mol on ACE2. Based on the results, it is known that this compound has a high potential to be a drug candidate for renoprotective.
  • Bruguirea gymnorrhyza Leaf Extract Metabolites: Oral Bioavailability and GI Absorption Predictions
    Nur Kuswanti, Nur Qomariyah, Erlix Rakhmad Purnama, Firas Khaleyla
    Journal of Medicinal and Chemical Sciences, 2024
    Background: Bruguirea gymnorrhyza is used to treat some diseases traditionally. Some scientific studies are important for its explanation and drug development. The aims of this study are to identify metabolites in B. gymnorrhyza leaf extract and predict their oral bioavailability and GI absorption associated with treating diseases.Methods: B. gymnorrhyza leaves were dried. Its flour was macerated in ethanol, then evaporated to produce an extract. The extract was analysed using Liquid Chromatography High Resolution-Mass Spectrophotometry (LCHR-MS) technique to identify its metabolites. The SwissADME tool was applied to predict their oral bioavailability and gastrointestinal (GI) absorption. Results: The LCHR-MS analysis resulted that B. gymnorrhyza leaf extract contained choline (65.18%) as the most dominant metabolite, followed by diisobutylphthalate (7.23%), isoleucine (5.62%), 2,2,6,6-tetramethyl-1-piperidinol (TEMPO) (4.18%), valine (3.52%), l-phenylalanine (2.07%), d-(+)-proline (1.70%), 2-[(3S)-1-(cyclohexylmethyl)-3-pyrrolidinyl]-1H-benzimidazole-5- carbonitrile (1.44%), adenine (1.39%), 2-[(2-chlorobenzyl)sulfanyl]-4,6-dimethylnicotinonitrile (1.26%), l-norleucine (1.24%), dibenzylamine (1.26%) and wogonin (1.05%). Most of them were predicted not to be oral bioavailable, except diisobutylphthalate, TEMPO, 2-[(3S)-1-(Cyclohexylmethyl)-3-pyrrolidinyl]-1H-benzimidazole-5-carbonitrile, and wogonin. However, most of the metabolites were predicted to be absorbed by GI wall highly, except choline. Conclusion: The B. gymnorrhyza leaf extract contains 13 main metabolites dominated by choline. They are mostly predicted not to be oral bioavailable and highly absorbed by GI tract. These results can be referred to direct and determine further steps of scientific studies of B. gymnorrhyza leaf extract and its metabolites as disease treating agents.
  • Effect of Averrhoa bilimbi Leaf Extract on Blood Glucose Level, Hepatosomatic Index (HSI), and Liver Histology of Diabetic Mice
    Alan Verangga, Nur Qomariyah, Firas Khaleyla
    Hayati Journal of Biosciences, 2024
    Averrhoa bilimbi leaf extract (BLE) contains high antioxidant levels. Antioxidants can suppress reactive oxygen species produced during hyperglycemic conditions in diabetes mellitus (DM), which cause damage to liver tissue. This study aimed to determine the BLE effect on fasting blood glucose (FBG), Hepatosomatic Index (HSI), and liver tissue damage. We used 24 mice in 6 different groups, divided by N (normal), K- (DM), K+ (DM+glibenclamide 0.013mg/20gBW), E1 (DM+ extract 6.3mg/20gBW), E2 (DM+ extract 8.4mg/20gBW), and E3 (DM + extract 10.5mg/20gBW). We used an alloxan dose of 120mg/kgBW to induce the DM and then treated with BLE for 14 days. We measured the fasting blood glucose using a glucometer. In addition, we evaluated the liver tissue damage with HSI and Hematoxylin-Eosin (HE) stained histological slides. The results showed that BLE significantly reduced the percentage of FBG and liver tissue damage, while HSI showed no significant difference. The most optimal extract dose was 8.4 mg/20gBW (E2 group), with an FBG decrease of 26.44%, a normal cell percentage of 88.56%, and an HSI score of 6.18%. Based on this finding, we concluded that bilimbi leaf extract could lower blood glucose and improve liver histology of diabetic mice but did not significantly affect HSI.
  • Potential of Bioactive Compound from Elephantopus scaber Linn. LEAF as Anti-Cancer through in Silico Test
    Yuliani Yuliani, Firas Khaleyla, Dwi Anggorowati Rahayu
    Journal of Medicinal and Chemical Sciences, 2023
    Elephantopus scaber contains secondary metabolites, such as triterpenoids, sesquiterpene lactones, elephantopin, epifriedelinol, lupeol, stiqmasterol, lupeolacetate, deoxyelephantopin, and isodeoxyelephantopin. The plant can be used for medicinal purposes to treat cancer, diabetes, leukemia, viral and bacterial infections, bronchitis, and hepatitis. Therefore, this research aims to isolate and identify the bio-active compounds in Elephantopus scaber leaf extract and to analyze the effectiveness of binding the constituents through molecular docking against NF-kB. The method used included two stages. The first stage was extraction, fractionation, isolation, and identification, while the second was the in silico test, including the sample preparation, molecular docking, and visualization. The results showed that 10 bioactive compounds had the potential as anti-cancer compounds. Based on the binding affinity of the molecular docking, the compounds with the lowest values were b-amyrin (-8.0 kcal/mal), a-amyrin (-6.9 kcal/mol), and Cycloartane-3.beta 25-diol (-6.9 kcal/mol). Furthermore, the three compounds have potential as anti-cancer agents.
  • Podia histology and ultrastructure of tropical sea cucumber Phyllophorus sp. (Phyllophoridae) and Colochirus quadrangularis (Cucumaridae) from Madura Strait, Indonesia
    Dwi Winarni, SIFERA ANGGITA ERIDIANTI, Listijani Suhargo, Firas Khaleyla, ISMILIANA WIRAWATI
    Biodiversitas, 2023
    Abstract. Winarni D, Eridianti SA, Suhargo L, Khaleyla F, Wirawati I. 2023. Podia histology and ultrastructure of tropical sea cucumber Phyllophorus sp. (Phyllophoridae) and Colochirus quadrangularis (Cucumaridae) from Madura Strait, Indonesia. Biodiversitas 24: 5685-5692. Phyllophorus sp. and Colochirus quadrangularis are sea cucumber species found in Madura Strait, East Java, Indonesia. Both species possess distinctive podia structures, which are protrusions on their body walls resembling spines. These structures serve as tube feet for movement (ventral podia) and sensory organs (dorsal papillae). This research aimed to compare the podia structures of Phyllophorus sp. and Colochirus quadrangularis. Five samples of each species were collected from the Madura Strait. Histological slides were prepared for the papillae (dorsal) and podia (ventral) on the anterior, median, and posterior body sections. Simultaneously, an examination of the ultrastructure was conducted using a scanning electron microscope (SEM). Analysis revealed differences between the podia of the two species. Phyllophorus sp. papillae had semi-flat tips, were non-suckered (SFNS), and exhibited squamous to short columnar epithelia, while their tube feet had flat tips, were non-suckered, and had columnar epithelia. Papillae were denser than tube feet. Conversely, C. quadrangularis papillae were pointed and non-suckered (PNS), and tube feet were flat and non-suckered (FNS). Notably, ossicle-dense areas in C. quadrangularis papillae had a pyramidal shape. In summary, the histology and ultrastructure of podia in these species displayed significant differences, highlighting their unique characteristics. They also imply to the adaptation biology of sea cucumber in Indonesian waters.
  • Ameliorative and Renoprotective Effect of Electrical Stimulation on Blood Sugar, Blood Urea Nitrogen (BUN), Creatinine Levels, and the Islets of Langerhans Weight in Diabetic Mice
    Suhariningsih Suhariningsih, S. Glory, F. Khaleyla, H. N. Kusumawati, M. Septriana, Y. Susilo, A. K. Yaqubi, S. D. Astuti, A. Syahrom
    Veterinary Medicine International, 2022
  • DNA barcoding of lamp shells (Brachiopoda: Lingula anatina) from Probolinggo, East Java, Indonesia
    Reni Ambarwati, Dwi Anggorowati Rahayu, Fida Rachmadiarti, Firas Khaleyla
    Biodiversitas, 2021
  • Science online learning during the covid-19 pandemic: Difficulties and challenges
    Wisanti, R Ambawati, EK Putri, DA Rahayu, F Khaleyla
    Journal of Physics Conference Series, 2021
  • Angiotensin-Converting Enzyme 2 (ACE2) of marine biota: A preliminary study of potential therapy for SARS-CoV-2 infection
    R Ambarwati, D A Rahayu, F Khaleyla, Wisanti, E K Putri
    Journal of Physics Conference Series, 2021
  • Effectiveness of sagittaria lancifolia as detergent phytoremediator
    H. Fitrihidajati, F. Rachmadiarti, F. Khaleyla, E. Kustiyaningsih
    Nature Environment and Pollution Technology, 2020
  • The effect of electric field, magnetic field, and infrared ray combination to reduce HOMA-IR index and GLUT 4 in diabetic model of Mus musculus
    Suhariningsih, Dwi Winarni, Saikhu A. Husen, Firas Khaleyla, Alfian Pramudita Putra, Suryani D. Astuti
    Lasers in Medical Science, 2020
  • Hepato-Renal Protective Effects of Mangosteen (Garcinia mangostana L.) Pericarp Extract in Streptozotocin-induced Diabetic Mice
    Saikhu Akhmad Husen, Septian Hary Kalqutny, Arif Nur Muhammad Ansori, Raden Joko Kuncoroningrat Susilo, Firas Khaleyla, Dwi Winarni
    Journal of Physics Conference Series, 2020
  • Effect of 2-methoxyethanol induction on mice (Mus musculus) liver, kidney and ovary
    W Darmanto, S P A Wahyuningsih, S A Husein, N S Aminah, A N Firdaus, E S Sajidah, M Izzatin, F Khaleyla
    Journal of Physics Conference Series, 2018
  • Activity assay of mangosteen (Garcinia mangostana L.) pericarp extract for decreasing fasting blood cholesterol level and lipid peroxidation in type-2 diabetic mice
    Saikhu Akhmad Husen, Dwi Winarni, Firas Khaleyla, Septian Hary Kalqutny, Arif Nur Muhammad Ansori
    Aip Conference Proceedings, 2017

RECENT SCHOLAR PUBLICATIONS

  • SIMPLE EXPERIMENTS TO IMPROVE CHILDREN'S SCIENCE PROCESS SKILLS GUIDED PENANG LEARNING STUDIO INDONESIAN SOCIETY ORGANIZATION (PERMAI)
    F Khaleyla, Y Yuliani, S Indana, E Susantini, R Raharjo, N Kuswanti
    Mitra Mahajana: Jurnal Pengabdian Masyarakat 7 (1), 134-140 , 2026
    2026
  • Pengembangan E-Book Interaktif Materi Sistem Pencernaan Manusia Untuk Melatih Keterampilan Berpikir Kritis Peserta Didik Kelas XI SMA
    N Kuswanti, F Khaleyla
    Berkala Ilmiah Pendidikan Biologi (BioEdu) 15 (1), 153-165 , 2026
    2026
  • HOTS-based science questions as assessment instrument for elementary school students: Examining validity and reliability
    E Susantini, MI Damayanti, F Khaleyla, M Huda
    International Journal of Education and Practice 14 (2), 338-359 , 2026
    2026
  • Pelatihan Tutor Sebaya sebagai Strategi Penguatan Pengetahuan Kesehatan Reproduksi Remaja pada Siswa SMP Labschool Unesa
    N Ducha, D Hariani, N Kuswanti, ER Purnama, F Khaleyla, ...
    J-Dinamika: Jurnal Pengabdian Masyarakat 10 (3), 461-464 , 2025
    2025
  • Biofloc technique training for biology teachers of Madrasah Aliyah at East Java to support food security in school
    F Khaleyla, R Ambarwati, I Isnawati, DA Rahayu, AL Fauzan, ...
    Journal of Community Service and Empowerment 6 (3), 573-580 , 2025
    2025
  • Morphological and Molecular Characterization of Pufferfish from Lekok Coastal Area, Pasuruan Indonesia
    VAE Panjaitan, AD Rangga, CAVT Sulung, DA Rahayu, F Khaleyla, ...
    Biosaintifika: Journal of Biology & Biology Education 17 (3), 382-394 , 2025
    2025
  • Effect of Longan Leaf Extract (Dimocarpus longan L.) on Total Cholesterol and Hepatic Histopathology in Type 2 Diabetes Mellitus Mice
    A Akhsan, N Kuswanti, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 14 (3), 340-346 , 2025
    2025
  • Effect of Different Types of High-Fat Diet (HFD) for Induction of Type 2 Diabetes Mellitus in Animal Model
    MG Dewistamara, N Qomariyah, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 14 (3), 331-339 , 2025
    2025
    Citations: 1
  • Improving Science Literacy using Basic Science Booklet for Indonesian Elementary Learners in Sanggar Belajar Penang, Malaysia
    Y Yuliani, R Raharjo, E Susantini, W Budjiastuti, S Indana, F Khaleyla
    Journal of Community Service and Empowerment 6 (2), 252-259 , 2025
    2025
  • The Pengaruh Ekstrak Daun Afrika (Vernonia amygdalina) Terhadap Kadar Gula Darah dan Penyembuhan Luka Mencit Diabetes Melitus Tipe II
    M Sharfina, N Kuswanti, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 14 (2), 204-211 , 2025
    2025
  • Academicians in Publishing Scientific Article
    F Khaleyla¹, UA Deta¹, NA Lestari¹, M Jakfar¹, RD Saputri¹
    Proceedings of the 2nd International Conference on Sciences, Mathematics … , 2025
    2025
  • Pengaruh Pemberian Ekstrak Minyak Maggot Black Soldier Fly Terhadap Penyembuhan Luka Sayat pada Kulit Mencit (Mus musculus)
    N Qomariyah, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 14 (1), 85-91 , 2025
    2025
    Citations: 1
  • Research trend of bivalves aquaculture in Southeast Asia during two decades based on bibliometric analysis in supporting 14 th SDG
    R Ambarwati, MZ Afnan, AL Fauzan, FA Agum Pratama, AW Ramadhana, ...
    E3S Web of Conferences 640, 01008 , 2025
    2025
    Citations: 1
  • Organization, density, and content of collagen in the body wall of sea cucumbers Acaudina rosettis and Phyllophorus sp.
    N Nabilla, I Shofiyah, D Alvitasari, S Sumarsih, F Khaleyla, I Wirawati, ...
    Aquaculture and Fisheries , 2024
    2024
    Citations: 5
  • Panduan Penulisan Artikel Ilmiah di Jurnal Berreputasi
    UA Deta, NA Lestari, M Jakfar, RD Saputri, F Khaleyla
    Mitra Edukasi dan Publikasi , 2024
    2024
  • Efek Ekstrak Daun Kedondong pada Kadar Gula Darah, Diameter Pulau Langerhans, dan Hepatosomatic Index Mencit Diabetes Melitus Tipe 2
    NA Sasmita, N Kuswanti, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 13 (1), 150-159 , 2024
    2024
    Citations: 6
  • Global trend of STEM Education for the SDGs of the last decade: A bibliometric analysis
    M Jakfar, UA Deta, NA Lestari, F Khaleyla, RD Saputri, A Arrosyidi
    E3S Web of Conferences 568, 04020 , 2024
    2024
    Citations: 4
  • Renoprotective effects of Cermai Leaves (Phyllanthus acidus (L.) Skeels) as a candidate for antidiabetic in silico
    ER Purnama, N Kuswanti, N Qomariyah, F Khaleyla, RAZ Aziz
    E3S Web of Conferences 513, 03004 , 2024
    2024
  • Bruguirea gymnorrhyza leaf extract metabolites: Oral bioavailability and gi absorption predictions
    N Kuswanti, N Qomariyah, ER Purnama, F Khaleyla
    Journal of Medicinal and Chemical Sciences 7, 518 , 2024
    2024
    Citations: 2
  • Effect of Averrhoa bilimbi Leaf Extract on Blood Glucose Level, Hepatosomatic Index (HSI), and Liver Histology of Diabetic Mice
    A Verangga, N Qomariyah, F Khaleyla
    HAYATI Journal of Biosciences 31 (1), 102-109 , 2024
    2024
    Citations: 5

MOST CITED SCHOLAR PUBLICATIONS

  • Science online learning during the covid-19 pandemic: difficulties and challenges
    Wisanti, R Ambawati, EK Putri, DA Rahayu, F Khaleyla
    Journal of Physics: Conference Series 1747 (1), 012007 , 2021
    2021
    Citations: 82
  • Activity assay of mangosteen ( Garcinia mangostana L.) pericarp extract for decreasing fasting blood cholesterol level and lipid peroxidation in type-2 diabetic mice
    SA Husen, D Winarni, F Khaleyla, SH Kalqutny, ANM Ansori
    AIP Conference Proceedings 1888 (1), 020026 , 2017
    2017
    Citations: 42
  • The effect of electric field, magnetic field, and infrared ray combination to reduce HOMA-IR index and GLUT 4 in diabetic model of Mus musculus
    Suhariningsih, D Winarni, SA Husen, F Khaleyla, AP Putra, SD Astuti
    Lasers in Medical Science 35 (6), 1315-1321 , 2020
    2020
    Citations: 26
  • Wawasan Perilaku Hidup Bersih dan Sehat (PHBS) di Masa Kenormalan Baru dalam Upaya Mencegah Penyebaran Covid-19 di Lingkungan Sekolah
    RK Asharo, A Arifiyanto, F Khaleyla, CT Rahmadi
    Mitra Mahajana: Jurnal Pengabdian Masyarakat 2 (2), 184-192 , 2021
    2021
    Citations: 21
  • Antioxidant activity assay of alpha-mangostin for amelioration of kidney structure and function in diabetic mice
    SA Husen, F Khaleyla, ANM Ansori, RJK Susilo, D Winarni
    1st International Conference Postgraduate School Universitas Airlangga … , 2017
    2017
    Citations: 20
  • Software preference for online learning of science and biology teachers under COVID-19 pandemic
    F Khaleyla, W Wisanti, R Ambarwati, DA Rahayu, EK Putri
    JPBI (Jurnal Pendidikan Biologi Indonesia) 7 (1), 35-42 , 2021
    2021
    Citations: 17
  • Hepato-Renal Protective Effects of Mangosteen ( Garcinia mangostana L.) Pericarp Extract in Streptozotocin-induced Diabetic Mice
    S Akhmad Husen, S Hary Kalqutny, A Nur Muhammad Ansori, ...
    Journal of Physics: Conference Series 1445 (1), 012018 , 2020
    2020
    Citations: 16
  • Efektivitas pemberian ekstrak daun pepaya jepang (Cnidoscolus aconitifolius) terhadap kadar kolesterol dan struktur histologi aorta mencit hiperkolesterolemia
    RM Maghfiroh, D Hariani, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 11 (1), 89-100 , 2022
    2022
    Citations: 11
  • Effectiveness of Sagittaria lancifolia as detergent phytoremediator
    H Fitrihidajati, F Rachmadiarti, F Khaleyla, E Kustiyaningsih
    Nature Environment and Pollution Technology 19 (4), 1723-1727 , 2020
    2020
    Citations: 10
  • Activity test of various mangosteen (Garcinia mangostana) pericarp extract fractions to decrease fasting blood cholesterol levels and lipid peroxidation activity in diabetic mice
    SA Husen, D Winarni, F Khaleyla, SH Kalqutny
    Berkala Penelitian Hayati 22 (1), 13-17 , 2016
    2016
    Citations: 10
  • Potential of bioactive compound from Elephantopus scaber Linn. LEAF as anti-cancer through in silico test
    Y Yuliani, F Khaleyla, RD Anggorowati
    Journal of Medicinal and Chemical Sciences 6 (8), 1773-1782 , 2023
    2023
    Citations: 7
  • DNA barcoding of lamp shells (Brachiopoda: Lingula anatina) from Probolinggo, East Java, Indonesia
    R Ambarwati, DA Rahayu, F Rachmadiarti, F Khaleyla
    Biodiversitas 22 (4), 1764-1774 , 2021
    2021
    Citations: 7
  • Metode Parafin untuk Sediaan Irisan Jaringan Hewan
    F Khaleyla, N Ducha, A Bashri
    Surabaya: Universitas Negeri Surabaya , 2021
    2021
    Citations: 7
  • Effect of 2-methoxyethanol induction on mice (Mus musculus) liver, kidney and ovary
    W Darmanto, SPA Wahyuningsih, SA Husein, NS Aminah, AN Firdaus, ...
    Journal of Physics: Conference Series 1116 (5), 052017 , 2018
    2018
    Citations: 7
  • Efek Ekstrak Daun Kedondong pada Kadar Gula Darah, Diameter Pulau Langerhans, dan Hepatosomatic Index Mencit Diabetes Melitus Tipe 2
    NA Sasmita, N Kuswanti, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 13 (1), 150-159 , 2024
    2024
    Citations: 6
  • Aktivitas Hepatoprotektif Ekstrak Daun Phyllanthus acidus L. pada Mencit Diabetes Mellitus Tipe 2
    EEP Oktaviona, N Qomariyah, F Khaleyla
    LenteraBio: Berkala Ilmiah Biologi 12 (3), 381-388 , 2023
    2023
    Citations: 6
  • Ameliorative and renoprotective effect of electrical stimulation on blood sugar, blood urea nitrogen (BUN), creatinine levels, and the islets of langerhans weight in diabetic mice
    S Suhariningsih, S Glory, F Khaleyla, HN Kusumawati, M Septriana, ...
    Veterinary Medicine International 2022 (1), 7922892 , 2022
    2022
    Citations: 6
  • Susceptibility of Aedes aegypti larvae in East Java towards commercial Temephos at different doses
    F Khaleyla, EA Rohmah, KC Mulyatno
    Jurnal Biologi Udayana 25 (2), 165-171 , 2021
    2021
    Citations: 6
  • Organization, density, and content of collagen in the body wall of sea cucumbers Acaudina rosettis and Phyllophorus sp.
    N Nabilla, I Shofiyah, D Alvitasari, S Sumarsih, F Khaleyla, I Wirawati, ...
    Aquaculture and Fisheries , 2024
    2024
    Citations: 5
  • Effect of Averrhoa bilimbi Leaf Extract on Blood Glucose Level, Hepatosomatic Index (HSI), and Liver Histology of Diabetic Mice
    A Verangga, N Qomariyah, F Khaleyla
    HAYATI Journal of Biosciences 31 (1), 102-109 , 2024
    2024
    Citations: 5