@unusa.ac.id
Faculty of Medicine
Universitas Nahdlatul Ulama Surabaya
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Friska Ayu, Moch. Sahri, Muslikha Nourma Rhomadhoni, Octavianus Hutapea, and Hafid Algristian
AIP Publishing
Akbar Reza Muhammad, Yunyastiti D. Palupi, Mega Astri, and Hafid Algristian
DiscoverSys, Inc.
Introduction: Breast cancer is the leading cause of death in women. Many studies of adjuvant therapy have used the Quran recitation (later will be mentioned as the murotal approach). The murotal approach has been shown to induce feelings of well-being, enhance therapeutic response, and aid in patient healing. This study aimed to analyze the effect of the murotal approach on lymphocytic cell activity in inducing programmed cancer cell necrosis in a breast cancer mouse model. Methods: After testing in a fully randomized design using 24 female mice (Mus musculus) BALB/c strain, a real-world experimental study with a control group design method. The mice were divided into four groups: negative control (K-), positive control (K+), treatment group (P1) which receiving the murotal approach for 2 hours and 30 minutes per day for a week, and the (P2) which receiving the murotal approach for 30 minutes in five times a day for a week. Mice were subcutaneously injected with DMBA 0.56 mg/20 g every 2 days for 3 weeks. The murotal approach was using specifically in Surah al-Faatihah and Al-Baaqarah from Qori' Al-Mathrud. Cancer tissue was harvested 5 weeks after her. The data were analyzed using the Kruskal-Wallis hypothesis test. Results: There was a significant difference (P<0.05) in the effect between the P2 treatment group that received murotal therapy for 30 minutes at each prayer time and the other groups. The efficacy of treatment murotal for 2 hours and 30 minutes per day does not affect the extent of lymphocytic infiltration. Conclusion: From the research, the dosage of murotal therapy to increase the degree of lymphocyte infiltration is for 30 minutes five times a day, or during prayer time.
Hafid Algristian, Tri Wahyu Bintari, Iradatus Solihah, Andik Ferdiantoro, Fatmanagri Napstyawati, and Retno Handajani
DiscoverSys, Inc.
Introduction: This research analyzes the behavioral and biological concepts of depression, aggression, and resilience. It also analyzes the Quran recitation as a noise-inducer for aggression but also encouraging intervention for depression. Method: Experimental research with a post-test-only control group design created an agitated depression model in mice as a basis for understanding the biological concepts of aggression. Healthy mice (Mus musculus balb/c) aged 10-12 weeks, weighing 20-25 grams, were random-allocated into 9 (nine) groups, namely the control group (K_ negative, depression, and aggression), depression group (DP_1, 2, 3), and aggression group (AP_1, 2, 3). The tail suspension approach triggered helplessness to form a depression model. Quran recitation was performed above 60 decibels as noise exposure triggers agitation and forms an aggression model. QRP performed under 60 decibels was assumed to create a resilience model. Depression, aggression, and resilience were measured using an eight-arm radial maze (TM) and immobile time when hung (TG). After the intervention, mice were sacrified and the brains harvested. Normal cells were counted in the average of ten microscopic fields using 40x objective lens magnification and HE staining. Results: The QRP alleviated the psychomotor retardation in the depression group, while the aggression group experienced a goal-directed behavioral activation as the cognition increased with psychomotor calm. Neuron cells were significantly different among groups; the optimum QRP dose was an hour once a day. Conclusions: The QRP intervention can improve depression and aggression, but also a source of noise-induced stress at a higher frequency. These results should be carefully generalized and need further research.
Nurfarah Lydia Hambali, Friska Ayu, Nicholas Tze Ping Pang, Mohd Amiruddin Mohd Kassim, Hafid Algristian, Moch. Sahri, Nelbon Giloi, Syed Sharizman Syed Abdul Rahim, Azizan Omar, Mohammad Saffree Jeffree,et al.
MDPI AG
The COVID-19 crisis has had repercussions on global mental wellbeing. This study aimed: (1) to identify the mediating role of psychological process variables, namely psychological mindedness, psychological mindfulness, and psychological inflexibility on the relationship between dysfunctional coping and psychopathologies in Indonesian undergraduate students subjected to national quarantine orders throughout July, 2020 and (2) to compare the level of anxiety, depression, and anxiety between Indonesian and Malaysian undergraduate students. A cross-sectional study was performed with 869 Indonesian undergraduate students from Nahdlatul Ulama University of Surabaya (UNUSA) and 515 undergraduate students from Universiti Malaysia Sabah (UMS). The BIPM, MAAS, AAQ-I, DASS-21, and Brief COPE were used to assess the research variables. The proportion who scored “moderate” and above for depression, anxiety, and stress were 20.2%, 25.0%, and 14.2%, respectively, in Malaysian samples and 22.2%, 35.0%, and 23.48% in Indonesian samples. In Study 1, psychological mindedness, psychological mindfulness, and psychological inflexibility significantly mediated the relationship between dysfunctional coping and psychopathologies. In Study 2, Indonesians demonstrated significantly higher anxiety and stress compared to Malaysian samples. Despite the contrasting COVID-19 situations in Malaysia and Indonesia, psychopathologies were more affected in Indonesia. Hence, our study suggests how crucial it is for mental health providers to consider promoting psychological mindedness, psychological mindfulness, and psychological flexibility to alleviate the corresponding psychopathologies among undergraduate students.
Hafid Algristian, Tri Wahyuni Bintarti, Rani Nur Mukaromatim Baroroh, Qorieatul Leila, Reina Ulfa, Amelia Krismawati, Mifa Nurdiana, Giftania Wardhani Sudjarwo, Adhi Wibowo Nurhidayat, Irawan Satriotomo,et al.
DiscoverSys, Inc.
Introduction: Lavender essential oils (LEO) have been known to have relaxing effects, improve mood, and treat anxiety, but the effect on multiple organ stress concurrently is unknown. This multiorgan stress is related to depression can be caused by chronic psychological stress due to excessive cortisol levels and can lead to organ damage. This study analyzed LEO in preventing depression and multiorgan failure using intraperitoneal injection of corticosteroids in animal-model. Methods: Rats (Rattus norvegicus) Wistar strain, male, aged 7-8 weeks were involved in this study. Depression in animal-model is defined by immobilization using tail suspension test and anhedonia using sucrose preference test. LEO 5% was diluted in virgin coconut oils as vehicle. Serum cortisol was analyzed using enzyme-linked immunosorbent assay (ELISA). Organs were extracted and processed using hematoxylin eosin staining. Results: The results of this study indicate that LEO was able to prevent damage to the glial cells, myocardiac cells, and gastrointestinal mast cells infiltration, but not to the hepatocytes and renal cells damage. LEO also induced behavioral activation as improvement of depression, but anhedonia was still remained. Conclusion: The effect of LEO is to prevent the increase in blood cortisol levels, thus reduce the reactivity of depressed individuals to stress, although the individual still has anhedonia as a residual symptoms
Hafid Algristian, Dian Dakwatul Choiriya, Diaz Syafrie Abdillah, Athiyatul Ulya, Hafizh Auliyan Sodali, Akbar Reza Muhammad, and Handayani Handayani
PAGEPress Publications
Children and adolescents are groups that are vulnerable to the radicalism influence. Curiosity and trial-error behaviour make them tend to do risk-taking behaviours. If it is not accompanied by good self-control ability, it will encourage them to do actions without thinking about the impact of these actions (impulsivity). If it is not accompanied by empathy, then it tends to be behaviour that opposes and disrupts the interests of others (aggressive behaviour). This study aimed to assess the “Children of the Country” program as an effort to de-radicalize children and adolescents. Quasi experimental study was used on 30 children and adolescents in a shelter of street children in Surabaya with a pretest/ post-test design. In order to measure the outcome of the program, a Radical Personality Test (RPT) was developed using big five personality construct. The increase of nationalism and positive behaviour score is not much to compensate the increase of negative radicalism score. This evaluation brings awareness to form a novel de-radicalization strategy for children and adolescents in the future.
Hafid Algristian
Scientific Foundation SPIROSKI
AIM: To analyse the effect of expressive writing in three selected cases.
 METHODS: Case studies presented from three psychiatric patients in a hospital-based outpatient clinic in Surabaya, Indonesia, between May 2017 and July 2018. Clinical changes have been observed and reported. Three patients were selected based on the possibility of whether they were able to or not to participate in similar cognitive therapy. These three cases were considered to represent a diagnosis for the psychotic and non-psychotic spectrum. The first case was a male with suicidal depression, the second was a woman with Suicidal Depression, and the third was schizophrenic woman elderly with auditory hallucinations. Expressive writing was formulated from literature studies and then implemented in these patients. Clinical changes were observed both associated with a reduction in symptoms as well as new symptoms. These non-directive measures allowed the author to observe the therapeutic effects and side effects of the intervention given.
 RESULTS: Three cases were analysed. Targets were determined by patients themselves without author's intervention. Each patient underwent 10 sessions in minimum and 32 sessions in maximum, from once per week to once per two weeks, and was stopped after it was considered reaching or approaching the desired target, or if unwanted side effects appeared. Main changes were “father hunger” symptom decreased in the first patient, self-esteem increased in the second patient, and cope with auditory hallucination in the third patient. Few adverse events also have been recorded such as masturbation as an obsession ritual of the first patient, possibly provoked double-identity symptom in the second patient and mental fatigue in the elderly in the third patient.
 CONCLUSION: Over six months of implementation, expressive writing show desirable results, yet some side effects in patients still need to be aware of.
Zulidyana D. Rusnalasari, Hafid Algristian, Tahegga Primananda Alfath, Andini D. Arumsari, and Immah Inayati
IOP Publishing
Education as the long-term solution to prevent and recover disasters in any kind of society faces a new challenge, social network. The increase number of internet users especially those in young age (adolescence) brings many consequences, related with anti-terrorism as a novel disaster management. Indonesia has Pancasila as the nation ideology, but the effect of the understanding this ideology has not been explored yet. Educators have focused on the material that would appear only in the exam, and tend to neglect the material that would be appearing in the real life. Previous study found that students are the vulnerable target of terrorism ideology, so they should be protected and guided. This study aimed to analyze the effect of between believe of the nation ideology and understanding the sensitive words for adolescence students. This research focused on the grade of students understanding about several sensitive words which often used by media to describe certain act or group which resulted to phobia and generalization. This phenomenon becomes greater time by time, along with the least effort to filter the media which now become bias and set aside the journalism ethic. The object of the research involved for about 193 students in age 13 - 21 which claimed as adolescence and active internet users. They have asked to answer several questions related with their understanding to several sensitive words like, “individualism, fundamentalism, radicalism, and terrorism”. Furthermore, the students’ believe about Pancasila as the nation ideology will also be questioned, whether this ideology create or effect the vulnerability of the students. The important of the ideology for them, is questionable. The result will show the grade of understanding and vulnerability of adolescence population to react the issue that probably become a trigger to disaster in sociopolitical.