Filipa Raquel Maia Fontes Lebre

@inl.int

Research Fellow - Nanosafety Group
International Iberian Nanotechnology Laboratory

Filipa Raquel Maia Fontes Lebre


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https://researchid.co/filebre

RESEARCH INTERESTS

Biomaterials; immunomodulation; tissue engineering
1233

Scholar Citations

17

Scholar h-index

23

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Patterning bacterial nanocellulose at cell-size scale using UV laser technology to create immunomodulatory interfaces
    L Costa, AF Carvalho, AJS Fernandes, JP Moura, R Silva-Carvalho, ...
    Biomaterials Advances, 214948 , 2026
    2026
  • A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment
    S Costa, AB Carneiro, F Lebre, J Meneses, A Ainla, C Moura, ...
    Advanced healthcare materials 15 (6), e02518 , 2026
    2026
    Citations: 3
  • Exploring the Interplay Between Particles and the Immune System
    TSM Lima, F Lebre
    Nanosafety: A Comprehensive Approach to Assess Nanomaterial Exposure on the … , 2025
    2025
    Citations: 1
  • Yeast-Derived Glucan Particles: Biocompatibility, Efficacy, and Immunomodulatory Potential as Adjuvants and Delivery Systems
    J Panão-Costa, M Colaço, S Jesus, F Lebre, MT Cruz, E Alfaro-Moreno, ...
    Pharmaceutics 17 (8), 1032 , 2025
    2025
    Citations: 5
  • Silk-Ovarioids: establishment and characterization of a human ovarian primary cell 3D-model system Open Access.
    VD Nisio, T Li, Z Xiao, K Papaikonomou, A Damdimopoulos, Á Végvári, ...
    Human Reproduction Open 2025 (3) , 2025
    2025
  • Sex-stratified osteochondral organ-on-chip model reveals sex-specific responses to inflammatory stimulation
    F Conceição, J Meneses, F Lebre, M Becker, N Araújo-Gomes, R Vos, ...
    Materials Today Bio 32, 101728 , 2025
    2025
    Citations: 12
  • Silk-Ovarioids: establishment and characterization of a human ovarian primary cell 3D-model system
    V Di Nisio, T Li, Z Xiao, K Papaikonomou, A Damdimopoulos, Á Végvári, ...
    Human Reproduction Open 2025 (3), hoaf042 , 2025
    2025
    Citations: 11
  • P23-20 Towards safer and sustainable MXene production
    SN Sankar, J Fernandes, G Araújo, F Cerqueira, P Alpuim, F Lebre, ...
    Toxicology Letters 399, S347-S347 , 2024
    2024
  • P02-19 A newly developed microfluidic system designed for the cultivation of 3D epidermis and full-thickness skin, tailored for nanoparticle safety evaluation
    A Ribeiro, S Costa, AS Nogueira, F Lebre, P Alpuim, E Alfaro-Moreno
    Toxicology Letters 399, S111-S111 , 2024
    2024
  • Eco‐Friendly Production of 2D Ti 3 C 2 T x MXene and Cytotoxicity Mitigation Toward Biomedical Applications
    SN Sankar, G Araujo, J Fernandes, F Cerqueira, P Alpuim, AR Ribeiro, ...
    Advanced Materials Interfaces 11 (24), 2400203 , 2024
    2024
    Citations: 10
  • Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro
    EM Panagiotou, A Damdimopoulos, T Li, E Moussaud-Lamodière, ...
    Toxicology 505, 153815 , 2024
    2024
    Citations: 15
  • Exploring the immunomodulatory properties of glucan particles in human primary cells
    S Jesus, JP Costa, M Colaço, F Lebre, D Mateus, AI Sebastião, MT Cruz, ...
    International journal of pharmaceutics 655, 123996 , 2024
    2024
    Citations: 12
  • Eco-Friendly Production of 2D Ti
    SN Sankar, G Araujo, J Fernandes, F Cerqueira, P Alpuim, AR Ribeiro, ...
    2024
  • Effects of chemical in vitro activation versus fragmentation on human ovarian tissue and follicle growth in culture
    J Hao, T Li, M Heinzelmann, E Moussaud-Lamodière, F Lebre, ...
    Human reproduction open 2024 (3), hoae028 , 2024
    2024
    Citations: 11
  • Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials
    S Costa, V Vilas-Boas, F Lebre, JM Granjeiro, CM Catarino, LM Teixeira, ...
    Trends in biotechnology 41 (10), 1282-1298 , 2023
    2023
    Citations: 51
  • Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses
    MLE Lundahl, M Mitermite, DG Ryan, S Case, NC Williams, M Yang, ...
    elife 11, e74690 , 2022
    2022
    Citations: 97
  • Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment
    F Lebre, N Chatterjee, S Costa, E Fernandez-de-Gortari, C Lopes, ...
    Nanomaterials 12 (11), 1810 , 2022
    2022
    Citations: 59
  • Mycobacterial para -Hydroxybenzoic Acid-Derivatives ( p HBADs) and Related Structures Induce Macrophage Innate Memory
    M Lundahl, DM Lynch, D Barnes, L McSweeney, A Gorman, F Lebre, ...
    ACS Chemical Biology 15 (9), 2415-2421 , 2020
    2020
    Citations: 4
  • Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease
    RK Shears, LC Jacques, G Naylor, L Miyashita, S Khandaker, F Lebre, ...
    Journal of allergy and clinical immunology 145 (4), 1272-1284. e6 , 2020
    2020
    Citations: 59
  • Pristine graphene induces innate immune training
    F Lebre, JB Boland, P Gouveia, AL Gorman, MLE Lundahl, RI Lynch, ...
    Nanoscale 12 (20), 11192-11200 , 2020
    2020
    Citations: 52

MOST CITED SCHOLAR PUBLICATIONS

  • The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation
    F Lebre, R Sridharan, MJ Sawkins, DJ Kelly, FJ O’Brien, EC Lavelle
    Scientific reports 7 (1), 2922 , 2017
    2017
    Citations: 245
  • Mucosal vaccines: recent progress in understanding the natural barriers
    O Borges, F Lebre, D Bento, G Borchard, HE Junginger
    Pharmaceutical research 27 (2), 211-223 , 2010
    2010
    Citations: 104
  • Modulation of immune responses by particulate materials
    F Lebre, CH Hearnden, EC Lavelle
    Advanced Materials 28 (27), 5525-5541 , 2016
    2016
    Citations: 99
  • Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses
    MLE Lundahl, M Mitermite, DG Ryan, S Case, NC Williams, M Yang, ...
    elife 11, e74690 , 2022
    2022
    Citations: 97
  • Intranasal administration of novel chitosan nanoparticle/DNA complexes induces antibody response to hepatitis B surface antigen in mice
    F Lebre, G Borchard, H Faneca, MC Pedroso de Lima, O Borges
    Molecular pharmaceutics 13 (2), 472-482 , 2016
    2016
    Citations: 88
  • Industrial grade 2D molybdenum disulphide (MoS 2 ): an in vitro exploration of the impact on cellular uptake, cytotoxicity, and inflammation
    C Moore, D Movia, RJ Smith, D Hanlon, F Lebre, EC Lavelle, HJ Byrne, ...
    2D Materials 4 (2), 025065 , 2017
    2017
    Citations: 73
  • Nanosafety: an evolving concept to bring the safest possible nanomaterials to society and environment
    F Lebre, N Chatterjee, S Costa, E Fernandez-de-Gortari, C Lopes, ...
    Nanomaterials 12 (11), 1810 , 2022
    2022
    Citations: 59
  • Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease
    RK Shears, LC Jacques, G Naylor, L Miyashita, S Khandaker, F Lebre, ...
    Journal of allergy and clinical immunology 145 (4), 1272-1284. e6 , 2020
    2020
    Citations: 59
  • Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles
    F Lebre, MCP de Lima, EC Lavelle, O Borges
    International journal of pharmaceutics 552 (1-2), 7-15 , 2018
    2018
    Citations: 55
  • Pristine graphene induces innate immune training
    F Lebre, JB Boland, P Gouveia, AL Gorman, MLE Lundahl, RI Lynch, ...
    Nanoscale 12 (20), 11192-11200 , 2020
    2020
    Citations: 52
  • Microfluidic-based skin-on-chip systems for safety assessment of nanomaterials
    S Costa, V Vilas-Boas, F Lebre, JM Granjeiro, CM Catarino, LM Teixeira, ...
    Trends in biotechnology 41 (10), 1282-1298 , 2023
    2023
    Citations: 51
  • Chitosan plus compound 48/80: formulation and preliminary evaluation as a hepatitis B vaccine adjuvant
    D Bento, S Jesus, F Lebre, T Gonçalves, O Borges
    Pharmaceutics 11 (2), 72 , 2019
    2019
    Citations: 44
  • Progress towards a needle-free hepatitis B vaccine
    F Lebre, G Borchard, MCP de Lima, O Borges
    Pharmaceutical research 28 (5), 986-1012 , 2011
    2011
    Citations: 29
  • Easy and effective method to generate endotoxin-free chitosan particles for immunotoxicology and immunopharmacology studies
    F Lebre, EC Lavelle, O Borges
    Journal of Pharmacy and Pharmacology 71 (6), 920-928 , 2019
    2019
    Citations: 28
  • Association of chitosan and aluminium as a new adjuvant strategy for improved vaccination
    F Lebre, D Bento, J Ribeiro, M Colaço, G Borchard, MCP de Lima, ...
    International journal of pharmaceutics 527 (1-2), 103-114 , 2017
    2017
    Citations: 27
  • Chitosan-based nanoparticles as a hepatitis B antigen delivery system
    F Lebre, D Bento, S Jesus, O Borges
    Methods in Enzymology 509, 127-142 , 2012
    2012
    Citations: 20
  • Exfoliation in endotoxin‐free albumin generates pristine graphene with reduced inflammatory properties
    F Lebre, D Hanlon, JB Boland, J Coleman, EC Lavelle
    Advanced Biosystems 2 (12), 1800102 , 2018
    2018
    Citations: 19
  • Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro
    EM Panagiotou, A Damdimopoulos, T Li, E Moussaud-Lamodière, ...
    Toxicology 505, 153815 , 2024
    2024
    Citations: 15
  • Sex-stratified osteochondral organ-on-chip model reveals sex-specific responses to inflammatory stimulation
    F Conceição, J Meneses, F Lebre, M Becker, N Araújo-Gomes, R Vos, ...
    Materials Today Bio 32, 101728 , 2025
    2025
    Citations: 12
  • Exploring the immunomodulatory properties of glucan particles in human primary cells
    S Jesus, JP Costa, M Colaço, F Lebre, D Mateus, AI Sebastião, MT Cruz, ...
    International journal of pharmaceutics 655, 123996 , 2024
    2024
    Citations: 12