@dbuniversity.ac.in
Assistant Professor and Department of Bio-Sciences
Assam Don Bosco University
Antibiotic Resistance; Microbial Interactions; Sociomicrobiology; Drug Discovery; Pharmacognosy
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Shivangi Borkotoky, Supriyo Sen, and Vedant Vikrom Borah
Springer Science and Business Media LLC
Arabinda Ghosh, Muddukrishnaiah Kotakonda, Vedant Vikrom Borah, and Nobendu Mukerjee
Wiley
SUSMA DAS, SHIVANGI BORKOTOKY, MAXMILLANDO RYMBAI, VEDANT V BORAH, JAYANTI D ROY, SHUNAN KAPING, PHILIPPE HELISSEY, and JAI N VISHWAKARMA
Springer Science and Business Media LLC
Rene Barbie Browne, Jai Narain Vishwakarma, Vedant Vikrom Borah, Raj Kumar Pegu, and Jayanti Datta Roy
Elsevier
Hakani D. Sympli, Supriyo Sen, Bahunlang Susngi, and Vedant Vikrom Borah
Journal of Pure and Applied Microbiology
Pleione maculata has no scientific reports on quantitative phytochemical and antibiofilm activity till date. The objective of the study was to quantify and determine medicinally important bioactivity in P. maculata and analyse its anti-biofilm activity against clinical isolates Staphyloccocus aureus, Klebsiella pneumoniae and Proteus mirabilis. P. maculata exhibited the highest Total Antioxidant Capacity (TAC) about 193.98±0.1 mg, highest Total Phenolic Content (TPC) at 552±0.0 mg and Total Flavonoid Content (TFC) were observed highest at 879.5±0.2 mg. The acetone and ethyl acetate extracts of P. maculata pseudobulb showed distinct and significant zone of inhibition (ZOI) against drug-resistant S.aureus about 16±0.00 mm (MIC 0.875 mg/mL), ZOI of acetonitrile pseudobulb extract against P. mirabilis was 15.33±0.4 mm (MIC 1 mg/mL), ZOI of acetonitrile extracts of leaves and stem, ethyl acetate extract of pseudobulb was 12±0.0 mm, 12±01.4 mm, 12±2.8 mm against K. pneumoniae (MIC 1.8 mg/mL, 0.68 mg/mL and 3 mg/mL). Acetonitrile extract of pseudobulbs exhibited the highest Minimum Biofilm Inhibition concentration (MBIC) at 0.25 mg/mL against S. aureus, water root extract inhibited attachment of K. pneumoniae with lowest MBIC value 0.093 mg/mL, water and acetone extract of leaves inhibited cell attachment of P. mirabilis at lowest MBIC 0.117 and 0.171 mg/mL. The UV-VIS absorption band of P. maculata extracts ranges from 204-665 nm indicating the presence of phenolic and flavonoid compounds. The study indicates the potentiality of P. maculata as a rich source of medicinal active compounds as an antibiofilm agent against antibiotic-resistant clinical isolates.
Santasree Sarma Biswas, Rene Barbie Browne, Vedant Vikrom Borah, and Jayanti Datta Roy
Springer Science and Business Media LLC
DEBAJANI BASUMATARY, MADAN KUMAR SHANKAR, KULLAIAH BYRAPPA, KANDARPA KUMAR SAIKIA, AJAZ AHMAD DAR, VEDANT VIKROM BORAH, PRANJIT SARMA, PRANAMI MAHANTA, MRITUNJAYA ASTHANA, and NAMRATHA KEERTHIRAJ
Springer Science and Business Media LLC
Upasana Sarma, Vedant V. Borah, Kandarpa Kr. Saikia, and N. K. Hazarika
Informa UK Limited
Vedant Vikrom Borah, Kandarpa Kumar Saikia, and Naba Kumar Hazarika
Elsevier BV
VV Borah, KK Saikia, P Chandra, NK Hazarika, and R Chakravarty
Elsevier BV