Harish Changotra
Verified @gmail.com
Scopus Publications
- Synergistic and divergent effects of dietary sugars on hepatocyte viability and steatosis
Ajay Kumar, Garhima Arora, Deepika Kumari, Harish Changotra, Samrat Chatterjee
Toxicology in Vitro, 2026 - Computational analysis identifies pathogenic nsSNPs in ATG10, an E2-like ubiquitin-conjugating enzyme of the autophagy pathway
Arpna, Ali Gharib Gharib, Arti Sharma, Jyoti Parkash, Harish Changotra
International Journal of Biological Macromolecules, 2026 - Brassinosteroid-mediated Physiological and Molecular Mechanisms in Plants Under Heavy Metal Stress
Deepak Kumar, Mohd Ali, Raman Tikoria, Parkirti, Roohi Sharma, Vikram, Rajesh Kumari Manhas, Harish Changotra, Puja Ohri
Brassinosteroids and Abiotic Stress Recent Developments on Physiological and Molecular Aspects, 2026
A class of steroidal phytohormones, known as brassinosteroids (BRs), is crucial for plant growth and development. Despite the fact that BRs were initially discovered and thoroughly investigated for their powerful growth-promoting physiological effects, the successive investigations in the following years precisely demonstrated the additional role of BRs in governing an array of processes, involving source/sink relationships, seed germination, photosynthesis, senescence, photomorphogenesis, flowering, as well as responses to abiotic and biotic stresses. Improvement in morphological parameters including germination, shoot and root length, yield, and biomass shows the boosting properties of BRs during heavy metal stress on the physical and chemical characteristics of plant growth. Due to the fact that BRs enhance the permeability of cell membranes and exhibit an affinity for membrane-bound proteins, plants administered with BRs undergoing heavy metal stress activate their defense system to scavenge reactive oxygen species (ROS) and reduce metal stress-induced lipid damage caused by ROS. They are known to improve both the quality and quantity of crop plants when administered exogenously at a specific dose and stage of plant growth under normal and stressed conditions. This chapter aims to provide insights into the role and mechanism of BRs during heavy metal stress in plants. - Correction to: Autophagy-related gene BECN1 single nucleotide polymorphisms in diseases (Molecular and Cellular Biochemistry, (2025), 480, 5, (2765-2769), 10.1007/s11010-024-05177-9)
Sargeet Kaur, Jitendraa Vashistt, Ajay Kumar, Jyoti Parkash, Harish Changotra
Molecular and Cellular Biochemistry, 2025 - Identification and Correlation of Novel Genes Associated with Progression of Alzheimer’s Disease
Tania Arora, Puneet Jain, Harshita Sharma, Vikash Prashar, Randeep Singh, Arti Sharma, Harish Changotra, Jyoti Parkash
Gene Expression the Journal of Liver Research, 2025
Background and objectives: Alzheimer’s disease (AD), an enduring neurodegenerative malady, contributes significantly to dementia cases, with late-onset AD being more common than early-onset AD. Despite extensive research to diagnose and treat AD, the intricate protein network impedes the development of efficacious drugs or targets. This study endeavored to identify previously undiscovered genetic reservoirs associated with AD progression, which could be targeted as therapeutic markers. Methods: Employing the robust tools of R-language, we dissected vast RNA sequence datasets comprising numerous samples and thousands of genes, pinpointing potential candidates implicated in AD’s trajectory. Thus, we selected the GSE203206 dataset, which includes AD patients and non-dementia controls, based on our criteria. After normalization, RNA-Seq data was compared, and log 2 fold change was calculated to determine the highly dysregulated genes. Further network analysis of genes and their associated miRNA was performed to determine a characteristic change in control and patient groups. Results: Differential expression analysis revealed 13 dysregulated genes in AD, wherein 12 were upregulated, and one was down-regulated. Furthermore, we identified hsa-miR-30-5p as a significant miRNA associated with AD, aligning with previous studies and highlighting its high involvement. Conclusions: This investigation has unveiled four novel genes and a paramount miRNA implicated in AD, thus furnishing potential targets for therapeutic interventions. These discoveries pave the way for further exploration into the intricate functions and implications of these genetic entities - Intronic region polymorphisms of autophagy gene ATG16L1 predispose individuals to Hepatitis B virus infection
Ambika Sharma, Ajay Duseja, Jyoti Parkash, Harish Changotra
Human Immunology, 2025 - Autophagy-related gene BECN1 single nucleotide polymorphisms in diseases
Sargeet Kaur, Jitendraa Vashistt, Ajay Kumar, Jyoti Parkash, Harish Changotra
Molecular and Cellular Biochemistry, 2025 - An artificial-restriction fragment length polymorphism (A-RFLP) method for genotyping intronic SNP rs7587633 C/T of ATG16L1
Ambika Sharma, Arti Sharma, Jyoti Parkash, Harish Changotra, and
Nucleosides Nucleotides and Nucleic Acids, 2025
SNPs could either cause a disorder or directly alter the efficacy of a particular treatment and act as biological markers. The SNP rs7587633 C/T present in the intronic region of the ATG16L1 gene has been studied for its role in psoriasis vulgaris and Palmoplantar pustulosis. To genotype rs7587633 C/T using PCR-RFLP no restriction site is present for any of the restriction enzymes at the SNP position. To develop an artificial-RFLP method for genotyping rs7587633 C/T, the forward primer was designed in such a way that it resulted in the creation of an EcoRI restriction site in the amplified product which could further be digested with EcoRI to find the genotype of the individual. The newly developed A-RFLP method was applied to genotype the SNP rs7587633 C/T in DNA samples of 100 healthy control individuals. The allelic and genotypic frequencies of the SNPs were 0.80(C), 0.20(T) and 65%(CC), 31%(CT) and 4%(TT), respectively. In conclusion, we developed an A-RFLP method to genotype the SNP rs7587633 C/T which is not present in any of the natural restriction sites and this method could be applied to genotype this SNP in various populations/diseases to find its role. - Mechanistic Evaluation of miRNAs and Their Targeted Genes in the Pathogenesis and Therapeutics of Parkinson’s Disease
Tania Arora, Gaurav Sharma, Vikash Prashar, Randeep Singh, Arti Sharma, Harish Changotra, Jyoti Parkash
Molecular Neurobiology, 2025 - Mutagenesis: A Promising Strategy for Elevating Plant Tolerance to Biotic Stress
Mohd Ali, Sandeep Kour, Deepak Kumar, Roohi Sharma, Parkirti Parkirti, Vikram, Rajesh Kumari Manhas, Harish Changotra, Puja Ohri
Plant Stress Tolerance Molecular Mechanisms and Breeding Strategies Volume Two, 2025
Modernization causes regular and noticeable changes in the environmental components, which consequently influence the productivity of agriculture globally. Environmental components include biotic and abiotic factors. Biotic factors like pests, bacteria, viruses, fungi, and nematodes degrade agriculture output and pose a potential risk to the growth and development of plants and hence affect their productivity. Keeping this in mind, crop development might prove to be an essential approach for ensuring the sustainability of food and plant-based products. Agrochemicals and formulations used in modern agricultural practices to control diseases are responsible for environmental contamination and have adverse effects on human health. Therefore, creating varieties of crops that are resistant to stress is a better strategy in the existing agricultural system. Furthermore, to produce such desired alleles for suitable crop development, a variety of genetic, biochemical, and metabolic variation must be required. Consequently, one of the most popular methods for reducing plant stressors is mutagenesis. Plant breeders favor methods such as physical (gamma radiation, ultraviolet rays, etc.), chemical (ethyl methane sulfonate, methyl methane sulfonate, sodium azide, etc.), and gene editing (ZFN, TALEN, and CRISPR) to induce mutagenesis. However, an essential aspect of plant breeding programs is to enhance genetic variation above and beyond naturally occurring variation. The current book chapter aims to provide insight into mutation breeding techniques in the mitigation of biotic stress in plants. - Microplastic: Interaction with Agroecosystem and Microbial Remediation
Deepak Kumar, Roohi Sharma, Raman Tikoria, Mohd Ali, Parkirti, Vikram, Rajesh Kumari Manhas, Harish Changotra, Puja Ohri
Microplastics and Soil Microbiome Recent Trends and Future Prospects, 2025 - Phytotoxins: Aquatic Plant Sources
Sandeep Kour, Mohd Ali, Deepak Kumar, Roohi Sharma, Parkirti, Vikram, Nitika Kapoor, Harish Changotra, Rajesh Kumari Manhas, Puja Ohri, Renu Bhardwaj
Biotoxins Biotechnological and Therapeutic Applications, 2025 - Bioactive Metabolites Produced by Microorganisms and Plants with Potential Application in Agriculture and Medicine
Mohd Ali, Deepak Kumar, Sandeep Kour, Parkirti, Roohi Sharma, Vikram, Rajesh Kumari Manhas, Harish Changotra, Puja Ohri, Nitika Kapoor, Renu Bhardwaj
Biotoxins Biotechnological and Therapeutic Applications, 2025 - Molecular epidemiology of human papillomavirus variants in cervical cancer in India
Nita Sharma, Harish Changotra, Manpreet Kaur
Indian Journal of Medical Research, 2024 - Mutagenic primer-based novel multiplex PCR–RFLP technique to genotype BECN1 SNPs rs10512488 and rs11552192
Sargeet Kaur, Jitendraa Vashistt, Arti Sharma, Jyoti Parkash, Ajay Kumar, Ajay Duseja, Harish Changotra
Molecular Biology Reports, 2024 - Autophagy Gene BECN1 Intronic Variant rs9890617 Predisposes Individuals to Hepatitis B Virus Infection
Sargeet Kaur, Jitendraa Vashistt, Harish Changotra
Biochemical Genetics, 2024 - Computational Investigation of Regulatory Region SNPs of Autophagy Gene BECN1
Sargeet Kaur, Jitendraa Vashistt, Harish Changotra
Defence Life Science Journal, 2024 - Identification of molecular signatures and molecular dynamics simulation of highly deleterious missense variants of key autophagy regulator beclin 1: a computational based approach
Sargeet Kaur, Jitendraa Vashistt, Harish Changotra
Journal of Biomolecular Structure and Dynamics, 2024 - Autophagy related gene 5 polymorphism rs17587319 (C/G) in asthmatic patients in North Indian population
Sargeet Kaur, Arpna, Durga Jha, Rajiv Khosla, Manpreet Kaur, Jyoti Parkash, Arti Sharma, Harish Changotra
Journal of Asthma, 2024 - Interactions Between Arbuscular Mycorrhizal Fungi and Other Microorganisms in the Rhizosphere and Hyphosphere
Deepak Kumar, Sandeep Kour, Mohd Ali, Roohi Sharma, Parkirti, Vikram, Harish Changotra, Rajesh Kumari Manhas, Puja Ohri
Arbuscular Mycorrhizal Fungi and Higher Plants Fundamentals and Applications, 2024 - Tinospora cordifolia: a potential neuroprotective agent against various neurodegenerative diseases
Randeep Singh, Chinmoyee Bhattacharyya, Vikash Prashar, Tania Arora, Arti Sharma, Harish Changotra, Jyoti Parkash
Journal of Herbal Medicine, 2023 - The Comparative Genomics and Network Analysis of eNOS by Using Different Bioinformatics Approaches
Arti Sharma, Jyoti Parkash, Arpita Banerjee, Randeep Singh, Nymphaea Arora, Tania Arora, Vikash Prashar, Priya Godara, Harish Changotra
Current Pharmacogenomics and Personalized Medicine, 2023 - ATG5: A central autophagy regulator implicated in various human diseases
Harish Changotra, Sargeet Kaur, Suresh Singh Yadav, Girdhari Lal Gupta, Jyoti Parkash, Ajay Duseja
Cell Biochemistry and Function, 2022 - Association of IRGM gene promoter polymorphisms with hepatitis B virus infection
Ambika Sharma, Ajay Duseja, Jyoti Parkash, Harish Changotra
Journal of Gene Medicine, 2022 - Dysregulated miRNAs in Progression and Pathogenesis of Alzheimer’s Disease
Tania Arora, Vikash Prashar, Randeep Singh, Tushar Singh Barwal, Harish Changotra, Arti Sharma, Jyoti Parkash
Molecular Neurobiology, 2022 - The AGE-RAGE Axis and RAGE Genetics in Chronic Obstructive Pulmonary Disease
Ambika Sharma, Sargeet Kaur, Malay Sarkar, B. C. Sarin, Harish Changotra
Clinical Reviews in Allergy and Immunology, 2021 - The autophagy gene ATG16L1 (T300A) variant is associated with the risk and progression of HBV infection
Ambika Sharma, Sargeet Kaur, Ajay Duseja, Harish Changotra
Infection Genetics and Evolution, 2020 - The beclin 1 interactome: Modification and roles in the pathology of autophagy-related disorders
Sargeet Kaur, Harish Changotra
Biochimie, 2020 - Identification of nsSNPs of transcription factor E2F1 predisposing individuals to lung cancer and head and neck cancer
Sanjay Singh, Ragothaman M. Yennamalli, Manish Gupta, Harish Changotra
Mutation Research Fundamental and Molecular Mechanisms of Mutagenesis, 2020 - E2F1 gene variant rs2071054 is a risk factor for head and neck and cervical cancers: A pilot study
Sanjay Singh, Sargeet Kaur, Manish Gupta, Rajeev Kumar Seam, Rajiv Khosla, Harish Changotra
Gene Reports, 2019 - E2F1 genetic variants and risk of cervical cancer in indian women
Sanjay Singh, Manish Gupta, Rajeev Kumar Seam, Harish Changotra
International Journal of Biological Markers, 2018 - Protective influences of N-acetylcysteine against alcohol abstinence-induced depression by regulating biochemical and GRIN2A, GRIN2B gene expression of NMDA receptor signaling pathway in rats
Rutuja Yawalkar, Harish Changotra, Girdhari Lal Gupta
Neurochemistry International, 2018 - The Nonsynonymous Polymorphisms Val276Met and Gly393Ser of E2F1 Gene are Strongly Associated with Lung, and Head and Neck Cancers
Sanjay Singh, Manish Gupta, Ambika Sharma, Rajeev Kumar Seam, Harish Changotra
Genetic Testing and Molecular Biomarkers, 2018 - Elucidation of bacterial species during childhood diarrhea through 16S rRNA Illumina Miseq approach
Nutan Thakur, Harish Changotra, Neelam Grover, Jitendraa Vashistt
Meta Gene, 2018 - Molecular characterization of diarrheagenic Escherichia coli pathotypes: Association of virulent genes, serogroups, and antibiotic resistance among moderate-to-severe diarrhea patients
Nutan Thakur, Swapnil Jain, Harish Changotra, Rahul Shrivastava, Yashwant Kumar, Neelam Grover, Jitendraa Vashistt
Journal of Clinical Laboratory Analysis, 2018 - Mutagenic primer-based PCR-RFLP assay for genotyping IRGM gene promoter variant rs4958843 (C/T)
Ambika Sharma, Harish Changotra
Journal of Clinical Laboratory Analysis, 2018 - Estimation of vibrio species incidences and antibiotic resistance in diarrhea patients
Nutan Thakur, Harish Changotra, Rahul Shrivastava, Neelam Grover, Jitendraa Vashistt
Asian Journal of Pharmaceutical and Clinical Research, 2018 - Rotavirus virus-like particles (RV-VLPs) vaccines: An update
Harish Changotra, Avni Vij
Reviews in Medical Virology, 2017 - Novel Artificial Restriction Fragment Length Polymorphism Methods for Genotyping Immunity-related GTPase M Promoter Polymorphisms
Ambika Sharma, Harish Changotra
Inflammatory Bowel Diseases, 2017 - Non-synonymous single nucleotide polymorphisms of ATG5 destabilize ATG12–ATG5/ATG16L1 complex: An enzyme with E3 like activity of ubiquitin conjugation system
Avni Vij, Ragothaman M. Yennamalli, Harish Changotra
Meta Gene, 2017 - Association of protein tyrosine phosphatase, non-receptor type 22 +1858C→T polymorphism and susceptibility to vitiligo: Systematic review and meta-analysis
Harish Changotra, Silky Agarwal
Indian Journal of Dermatology Venereology and Leprology, 2017 - A novel Tetra-primer ARMS-PCR based assay for genotyping SNP rs12303764(G/T) of human Unc-51 like kinase 1 gene
Rohit Randhawa, Ajay Duseja, Harish Changotra
Molecular Biology Reports, 2017 - Next Generation Sequencing: An amalgam of disease biology and computer algorithms for comprehensive exploration of Infectious agents
11th Indiacom 4th International Conference on Computing for Sustainable Global Development Indiacom 2017, 2017 - Molecular Analysis of VP7 Gene of Rotavirus G1 Strains Isolated from North India
Swapnil Jain, Jitendraa Vashistt, Kanika Gupta, Ashok Kumar, Harish Changotra
Current Microbiology, 2016 - Predominance of unusual rotavirus G1P[6] strain in North India: An evidence from hospitalized children and adult diarrheal patients
Swapnil Jain, Nutan Thakur, Jitendraa Vashistt, Neelam Grover, Triveni Krishnan, Harish Changotra
Infection Genetics and Evolution, 2016 - Investigating regulatory signatures of human autophagy related gene 5 (ATG5) through functional in silico analysis
Avni Vij, Rohit Randhawa, Jyoti Parkash, Harish Changotra
Meta Gene, 2016 - Liver X Receptor-α polymorphisms (rs11039155 and rs2279238) are associated with susceptibility to vitiligo
Silky Agarwal, Gurjinder Kaur, Rohit Randhawa, Vikram Mahajan, Rohit Bansal, Harish Changotra
Meta Gene, 2016 - Prevalence of rotavirus, norovirus and enterovirus in diarrheal diseases in Himachal Pradesh, India
Swapnil Jain, Nutan Thakur, Neelam Grover, Jitendraa Vashistt, Harish Changotra
Virusdisease, 2016 - Depression mediates impaired glucose tolerance and cognitive dysfunction: A neuromodulatory role of rosiglitazone
Sita Sharan Patel, Vineet Mehta, Harish Changotra, Malairaman Udayabanu
Hormones and Behavior, 2016 - Epstein-Barr virus glycoprotein gM can interact with the cellular protein p32 and knockdown of p32 impairs virus
Harish Changotra, Susan M. Turk, Antonio Artigues, Nagendra Thakur, Mindy Gore, Martin I. Muggeridge, Lindsey M. Hutt-Fletcher
Virology, 2016 - Unc-51 like kinase 1 (ULK1) in silico analysis for biomarker identification: A vital component of autophagy
Rohit Randhawa, Manika Sehgal, Tiratha Raj Singh, Ajay Duseja, Harish Changotra
Gene, 2015 - Rotaviruses: Is their surveillance needed?
Swapnil Jain, Jitendraa Vashistt, Harish Changotra
Vaccine, 2014 - An improved method for the isolation of hepatitis B virus DNA from human serum
Harish Changotra, Prabodh K. Sehajpal
Indian Journal of Virology, 2013 - Type I and type II interferons inhibit the translation of murine norovirus proteins
Harish Changotra, Yali Jia, Tara N. Moore, Guangliang Liu, Shannon M. Kahan, Stanislav V. Sosnovtsev, Stephanie M. Karst
Journal of Virology, 2009 - Tumor necrosis factor-α and transforming growth factor-β1 polymorphisms in bronchial asthma
PrabodhK Sehajpal, Ajay Kumar, Vikas Gupta, Harish Changotra, BC Sarin
Indian Journal of Medical Sciences, 2008 - Diagnosing different stages of hepatitis B infection using a competitive polymerase chain reaction assay
H Changotra, A Dwivedi, AK Nayyar, PK Sehajpal
Indian Journal of Medical Microbiology, 2008 - TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine
Charu Dogra, Harish Changoua, Nia Wedhas, Xuezhong Qin, Jon E. Wergedal, Ashok Kumar
FASEB Journal, 2007 - Murine norovirus 1 infection is associated with histopathological changes in immunocompetent hosts, but clinical disease is prevented by STAT1-dependent interferon responses
Shannon M. Mumphrey, Harish Changotra, Tara N. Moore, Ellen R. Heimann-Nichols, Christiane E. Wobus, Michael J. Reilly, Mana Moghadamfalahi, Deepti Shukla, Stephanie M. Karst
Journal of Virology, 2007 - Regulation of phosphatidylinositol 3-kinase (PI3K)/Akt and nuclear factor-kappa B signaling pathways in dystrophin-deficient skeletal muscle in response to mechanical stretch
Charu Dogra, Harish Changotra, Jon E. Wergedal, Ashok Kumar
Journal of Cellular Physiology, 2006 - Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-κB and degradation of MyoD protein
Charu Dogra, Harish Changotra, Subburaman Mohan, Ashok Kumar
Journal of Biological Chemistry, 2006 - Quantitative detection of serum HBV DNA levels employing a new S gene based cPCR assay
H. Changotra, P. K. Sehajpal
Archives of Virology, 2005 - Association of G-308A TNF-α polymorphism with bronchial asthma in a North Indian population
Vikas Gupta, B. C. Sarin, Harish Changotra, P. K. Sehajpal
Journal of Asthma, 2005
RECENT SCHOLAR PUBLICATIONS
- Brassinosteroid‐mediated Physiological and Molecular Mechanisms in Plants Under Heavy Metal Stress
D Kumar, M Ali, R Tikoria, Parkirti, R Sharma, Vikram, RK Manhas, ...
Brassinosteroids and Abiotic Stress: Recent Developments on Physiological … , 2026
2026 - Computational analysis identifies pathogenic nsSNPs in ATG10, an E2-like ubiquitin-conjugating enzyme of the autophagy pathway
Arpna, AG Gharib, A Sharma, J Parkash, H Changotra
International Journal of Biological Macromolecules, 149933 , 2025
2025 - Synergistic and divergent effects of dietary sugars on hepatocyte viability and steatosis
A Kumar, G Arora, D Kumari, H Changotra, S Chatterjee
Toxicology in Vitro, 106148 , 2025
2025 - Identification and Correlation of Novel Genes Associated with Progression of Alzheimer’s Disease
T Arora, P Jain, H Sharma, V Prashar, R Singh, A Sharma, H Changotra, ...
Gene Expression 24 (2), 85-94 , 2025
2025 - Correction to: Autophagy-related gene BECN1 single nucleotide polymorphisms in diseases
S Kaur, J Vashistt, A Kumar, J Parkash, H Changotra
Molecular and Cellular Biochemistry 480 (6), 3923-3924 , 2025
2025 - Microplastic: Interaction with Agroecosystem and Microbial Remediation
D Kumar, R Sharma, R Tikoria, M Ali, Parkirti, Vikram, RK Manhas, ...
Microplastics and Soil Microbiome: Recent trends and Future Prospects, 91-135 , 2025
2025 - Microplastic: Interaction with Agroecosystem and Microbial
RK Manhas, H Changotra, P Ohri
Microplastics and Soil Microbiome: Recent trends and Future Prospects, 91 , 2025
2025 - Intronic region polymorphisms of autophagy gene ATG16L1 predispose individuals to Hepatitis B virus infection
A Sharma, A Duseja, J Parkash, H Changotra
Human Immunology 86 (3), 111293 , 2025
2025 - Autophagy-related gene BECN1 single nucleotide polymorphisms in diseases
S Kaur, J Vashistt, A Kumar, J Parkash, H Changotra
Molecular and Cellular Biochemistry 480 (5), 2765-2769 , 2025
2025
Citations: 2 - An artificial-restriction fragment length polymorphism (A-RFLP) method for genotyping intronic SNP rs7587633 C/T of ATG16L1
A Sharma, Arpna, A Sharma, J Parkash, H Changotra
Nucleosides, Nucleotides & Nucleic Acids 44 (4), 291-301 , 2025
2025
Citations: 2 - Bioactive Metabolites Produced by Microorganisms and Plants with Potential Application in Agriculture and Medicine
M Ali, D Kumar, S Kour, Parkirti, R Sharma, Vikram, RK Manhas, ...
Biotoxins: Biotechnological and Therapeutic Applications, 467-490 , 2025
2025
Citations: 2 - Phytotoxins: Aquatic Plant Sources
S Kour, M Ali, D Kumar, R Sharma, Parkirti, Vikram, N Kapoor, ...
Biotoxins: Biotechnological and Therapeutic Applications, 173-195 , 2025
2025 - Mutagenesis: A Promising Strategy for Elevating Plant Tolerance to Biotic Stress
M Ali, S Kour, D Kumar, R Sharma, P Parkirti, RK Manhas, H Changotra, ...
Plant Stress Tolerance, 52-69 , 2025
2025 - Molecular epidemiology of human papillomavirus variants in cervical cancer in India
N Sharma, H Changotra, M Kaur
The Indian Journal of Medical Research 160 (6), 531 , 2025
2025
Citations: 2 - Mechanistic evaluation of miRNAs and their targeted genes in the pathogenesis and therapeutics of Parkinson’s disease
T Arora, G Sharma, V Prashar, R Singh, A Sharma, H Changotra, ...
Molecular Neurobiology 62 (1), 91-108 , 2025
2025
Citations: 7 - Plant MicroRNAs: Identification and Their Application in Disease Management
S Kour, D Kumar, M Ali, Parkirti, R Sharma, Vikram, RK Manhas, ...
Molecular and Biotechnological Tools for Plant Disease Management, 319-347 , 2024
2024 - Identification of molecular signatures and molecular dynamics simulation of highly deleterious missense variants of key autophagy regulator beclin 1: a computational based approach
S Kaur, J Vashistt, H Changotra
Journal of Biomolecular Structure and Dynamics 42 (18), 9691-9704 , 2024
2024
Citations: 4 - and Their Application in Disease Management
RK Manhas, H Changotra, P Ohri
Molecular and Biotechnological Tools for Plant Disease Management, 319 , 2024
2024 - Mutagenic primer-based novel multiplex PCR–RFLP technique to genotype BECN1 SNPs rs10512488 and rs11552192
S Kaur, J Vashistt, A Sharma, J Parkash, A Kumar, A Duseja, H Changotra
Molecular Biology Reports 51 (1), 384 , 2024
2024
Citations: 2 - Autophagy Gene BECN1 Intronic Variant rs9890617 Predisposes Individuals to Hepatitis B Virus Infection
S Kaur, J Vashistt, H Changotra
Biochemical Genetics 62 (5), 3336-3349 , 2024
2024
Citations: 3
MOST CITED SCHOLAR PUBLICATIONS
- TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine
C Dogra, H Changotra, N Wedhas, X Qin, JE Wergedal, A Kumar
FASEB journal: official publication of the Federation of American Societies … , 2007
2007
Citations: 316 - Murine norovirus 1 infection is associated with histopathological changes in immunocompetent hosts, but clinical disease is prevented by STAT1-dependent interferon responses
SM Mumphrey, H Changotra, TN Moore, ER Heimann-Nichols, CE Wobus, ...
Journal of virology 81 (7), 3251-3263 , 2007
2007
Citations: 292 - Tumor necrosis factor-like weak inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor-κB and degradation of MyoD protein
C Dogra, H Changotra, S Mohan, A Kumar
Journal of Biological Chemistry 281 (15), 10327-10336 , 2006
2006
Citations: 222 - Regulation of phosphatidylinositol 3‐kinase (PI3K)/Akt and nuclear factor‐kappa B signaling pathways in dystrophin‐deficient skeletal muscle in response to mechanical stretch
C Dogra, H Changotra, JE Wergedal, A Kumar
Journal of cellular physiology 208 (3), 575-585 , 2006
2006
Citations: 153 - Type I and type II interferons inhibit the translation of murine norovirus proteins
H Changotra, Y Jia, TN Moore, G Liu, SM Kahan, SV Sosnovtsev, ...
Journal of virology 83 (11), 5683-5692 , 2009
2009
Citations: 127 - The beclin 1 interactome: Modification and roles in the pathology of autophagy-related disorders
S Kaur, H Changotra
Biochimie 175, 34-49 , 2020
2020
Citations: 126 - ATG5: A central autophagy regulator implicated in various human diseases
H Changotra, S Kaur, SS Yadav, GL Gupta, J Parkash, A Duseja
Cell biochemistry and function 40 (7), 650-667 , 2022
2022
Citations: 104 - Molecular characterization of diarrheagenic Escherichia coli pathotypes: Association of virulent genes, serogroups, and antibiotic resistance among moderate‐to …
N Thakur, S Jain, H Changotra, R Shrivastava, Y Kumar, N Grover, ...
Journal of clinical laboratory analysis 32 (5), e22388 , 2018
2018
Citations: 69 - Rotaviruses: is their surveillance needed?
S Jain, J Vashistt, H Changotra
Vaccine 32 (27), 3367-3378 , 2014
2014
Citations: 68 - The AGE-RAGE axis and RAGE genetics in chronic obstructive pulmonary disease
A Sharma, S Kaur, M Sarkar, BC Sarin, H Changotra
Clinical Reviews in Allergy & Immunology 60 (2), 244-258 , 2021
2021
Citations: 65 - Depression mediates impaired glucose tolerance and cognitive dysfunction: a neuromodulatory role of rosiglitazone
SS Patel, V Mehta, H Changotra, M Udayabanu
Hormones and behavior 78, 200-210 , 2016
2016
Citations: 55 - Rotavirus virus‐like particles (RV‐VLPs) vaccines: An update
H Changotra, A Vij
Reviews in medical virology 27 (6), e1954 , 2017
2017
Citations: 48 - Dysregulated miRNAs in progression and pathogenesis of Alzheimer’s disease
T Arora, V Prashar, R Singh, TS Barwal, H Changotra, A Sharma, ...
Molecular Neurobiology 59 (10), 6107-6124 , 2022
2022
Citations: 39 - Association of G-308A TNF-α polymorphism with bronchial asthma in a north Indian population
V Gupta, BC Sarin, H Changotra, PK Sehajpal
Journal of Asthma 42 (10), 839-841 , 2005
2005
Citations: 38 - Prevalence of rotavirus, norovirus and enterovirus in diarrheal diseases in Himachal Pradesh, India
S Jain, N Thakur, N Grover, J Vashistt, H Changotra
VirusDisease, 1-7 , 2016
2016
Citations: 33 - Unc-51 like kinase 1 (ULK1) in silico analysis for biomarker identification: a vital component of autophagy
R Randhawa, M Sehgal, TR Singh, A Duseja, H Changotra
Gene 562 (1), 40-49 , 2015
2015
Citations: 32 - Tumor necrosis factor-α and transforming growth factor-β1 polymorphisms in bronchial asthma
A Kumar, V Gupta, H Changotra, BC Sarin, PK Sehajpal
Medknow Publications on behalf of Indian Journal of Medical Sciences Trust , 2008
2008
Citations: 28 - Protective influences of N-acetylcysteine against alcohol abstinence-induced depression by regulating biochemical and GRIN2A, GRIN2B gene expression of NMDA receptor signaling …
R Yawalkar, H Changotra, GL Gupta
Neurochemistry international 118, 73-81 , 2018
2018
Citations: 27 - Investigating regulatory signatures of human autophagy related gene 5 (ATG5) through functional in silico analysis
A Vij, R Randhawa, J Parkash, H Changotra
Meta gene 9, 237-248 , 2016
2016
Citations: 25 - Liver X Receptor-α polymorphisms (rs11039155 and rs2279238) are associated with susceptibility to vitiligo
S Agarwal, G Kaur, R Randhawa, V Mahajan, R Bansal, H Changotra
Meta Gene 8, 33-36 , 2016
2016
Citations: 23
