MORA MURRI PIERRI

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Endocrine Diseases Research Group, University Clinical Virgen de la Victoria Hospital
IBIMA

MORA MURRI PIERRI


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RESEARCH INTERESTS

Obesity, Metabolism, Metabolic syndrome, PCOS
71

Scopus Publications

Scopus Publications

  • Intra-Individual Variability of Lipoprotein(a) After Acute Coronary Syndrome: A Long-Term Cohort Study
    Nelsa González-Aguado, Jose Ignacio Larrubia-Valle, Rafael Franco-Hita, Alberto Piserra-López, Arancha Díaz-Expósito, Victoria García-Ruiz, Fernando Puyol-Ruiz, Óscar Barquero-Alegre, Fernando Carrasco Chinchilla, Antonio Domínguez-Franco, Amalio Ruiz-Salas, Jorge Rodríguez-Capitán, Alejandro Pérez-Cabeza, Mora Murri, Francisco Javier Pavon-Moron, Juan José Gómez-Doblas, Manuel Jiménez-Navarro, Francesco Costa
    Journal of Clinical Medicine, 2026
    Background: Lipoprotein(a) [Lp(a)] is a causal and independent risk factor for atherosclerotic cardiovascular disease (ASCVD) and is largely genetically determined. However, recent studies indicate significant intra-individual variability, particularly among patients with intermediate Lp(a) levels (30–50 mg/dL). Yet, data on long-term variability are limited, and acute coronary syndrome (ACS) may further influence Lp(a) levels, raising questions regarding the optimal timing of assessment after ACS. Methods: We studied 235 ACS patients across two follow-up cohorts. Baseline Lp(a) was measured 24 h before hospital discharge. Cohort A had follow-up measurements at 4 months and 8 months; Cohort B had them at 5 years. Clinically meaningful intra-individual variability was defined as ≥20 mg/dL or ≥25% change. Results: 57.9% of patients exhibited clinically significant Lp(a) variability. Changes in risk category occurred in 15.3% of patients in the baseline high-risk group, 60.6% of patients in the intermediate-risk group, and 5.5% of patients in the baseline low-risk group. In the multivariable analysis, incomplete revascularization was an independent predictor of high Lp(a) variability (odds ratio (OR) 2.22; 95% confidence interval (CI) 1.14–4.31; p = 0.02) while female sex and age-adjusted menopause showed a trend (OR 1.92; 95% CI 0.93–4.00; p = 0.08 and OR 11.18; 95% CI 0.79–157.58; p = 0.07, respectively) without reaching statistical significance. The median absolute changes from baseline to 4-month and from baseline to 5-year follow-up were 7.9 mg/dL (interquartile range (IQR) 3.0–18.9) and 10.7 mg/dL (IQR 3.0–21.7), respectively. Concordance between 4- and 8-month Lp(a) measurements was excellent. Conclusions: Early post-ACS intra-individual variability in Lp(a) is common, mainly affecting risk reclassification in intermediate-risk patients. In those patients, early, targeted, repeat Lp(a) measurement may improve cardiovascular risk stratification, whereas mid- to long-term reassessment appears unnecessary.
  • Comparing Acute Effects of Caffeine Delivery Forms on Cross-Training Performance: A Randomized Placebo-Controlled Crossover Trial
    Salvador Vargas-Molina, Diego A. Bonilla, Manuel García-Sillero, Sergio Iglesias-Placed, Mora Murri, Fernando Martín-Rivera, Javier Benítez-Porres
    Nutrients, 2026
    Background/Objectives: The aim of this study was to compare the different forms of caffeine (CAF) administration in CrossFit® participants. The countermovement jump (CMJ), the rate of perceived exertion (RPE), the total number of repetitions, and the maximum (HRmax) and mean heart rate (HRmean) were evaluated. Methods: Fourteen males with more than six months of continuous CrossFit® training (30.9 [5.62] years, 179 [1.33] cm, 78 [5.75] kg, 24.3 [1.33] kg·m−2) participated in this randomized, placebo-controlled, crossover study. Participants were randomized in a repeated measures design using caffeine capsule (CC), caffeine chewing gum (CCG), and caffeine mouth rinse (CMR) protocols, along with a placebo group (PG). Participants were unaware of whether any of the delivery methods contained caffeine. A 7-day washout period before each crossover was used. To ensure ecological validity, we replicated the real-world practice of CAF ingestion 30 min prior to training, mirroring typical athlete pre-workout routines. The participants of CrossFit® performed the ‘Cindy’ protocol, and the CMJ as a primary outcome was measured pre- and post-intervention, while the RPE, HR, and the number of repetitions were tracked at the end of the workout for comparisons. Results: No significant differences were found between CAF forms in internal load measures (RPE, HRmax, HRmean) or the number of repetitions. While no changes were observed with other CAF forms, CMR significantly improved the CMJ performance compared to the baseline (Δ: +3.5; Cohen’s dunb: 0.51], which exceeded the estimated SWC by approximately three-fold. However, the inferential analysis revealed no significant main effects of the caffeine administration method on any measured outcomes. Conclusions: While CAF delivery forms did not improve internal load measures or performance parameters, such as the RPE, HR, or the total number of repetitions, the caffeine mouth rinse (CMR) showed a potentially meaningful improvement in CMJ performance after CrossFit® training in participants with a certain level of experience.
  • Mitochondria, Sex, and Cardiovascular Disease: A Complex Interplay
    Andrea Iboleon-Jimenez, Alberto Contreras-Muñoz, Cristian Peláez-Berdún, Rafael Franco-Hita, Alba Sesmero, Ainhoa Robles-Mezcua, Jose M. García-Pinilla, Manuel Jimenez-Navarro, Mora Murri
    International Journal of Molecular Sciences, 2025
    Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide. Increasing evidence indicates that sex differences significantly influence the development, progression, and outcomes of CVDs. Recent advances have highlighted the central role of mitochondria, not only as cellular energy hubs but also as key regulators of oxidative stress, inflammation, and apoptosis, in mediating sex-specific cardiovascular responses. This review explores sexual dimorphism in cardiovascular disease, focusing on the interplay between mitochondrial function and sex hormones in cardiovascular tissues. We summarize current evidence on the molecular, hormonal, and cellular mechanisms contributing to sex-based disparities in cardiovascular outcomes. Preclinical studies suggest that female cardiac mitochondria may exhibit greater antioxidant capacity and produce fewer reactive oxygen species than male mitochondria, contributing to enhanced cardioprotection. Estrogen has been shown to influence mitochondrial bioenergetics and gene expression, affecting vascular tone, inflammation, and cardiac remodelling, whereas the role of testosterone remains less well defined. Additionally, sex-specific mitochondrial signalling responses have been reported under cardiac stress conditions, which may underlie differences in disease presentation and progression. A better understanding of how sex modulates mitochondrial function could improve risk stratification and support the development of personalized prevention and treatment strategies. Further research is needed to translate these mechanistic insights into clinical practice.
  • Cachexia Phenotyping Through Morphofunctional Assessment and Mitocondrial Biomarkers (GDF-15 and PGC-1α) in Idiopathic Pulmonary Fibrosis
    Alicia Sanmartín-Sánchez, Rocío Fernández-Jiménez, Josefina Olivares-Alcolea, Eva Cabrera-César, Francisco Espíldora-Hernández, Isabel Vegas-Aguilar, María del Mar Amaya-Campos, Víctor José Simón-Frapolli, María Villaplana-García, Isabel Cornejo-Pareja, Ana Sánchez-García, Mora Murri, Patricia Guirado-Peláez, Álvaro Vidal-Suárez, Lourdes Garrido-Sánchez, Francisco J. Tinahones, Jose Luis Velasco-Garrido, Jose Manuel García-Almeida
    Nutrients, 2025
    Background/Objetives: Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor prognosis. Nutritional disorders, particularly cachexia, significantly impact morbidity and mortality in IPF but remain under-investigated. This study aimed to characterize cachexia phenotypes in IPF through morphofunctional assessment (MFA) and to evaluate their prognostic relevance, including the role of mitochondrial biomarkers. Methods: In this prospective bicenter study, 85 IPF patients underwent MFA including bioelectrical impedance vector analysis (BIVA), nutritional ultrasound (NU), and T12-level computed tomography (T12-CT) for body composition. Functional and strength assessments included timed up and go test (TUG) and handgrip strength (HGS), respectively. Cachexia was defined by Evans’ criteria, Martin’s CT-based criteria, and our IPF-specific proposed definition. Serum GDF-15 and PGC-1α levels were also measured. Results: Cachexia prevalence varied by definition: 24.71% (Evans), 29.5% (Martin) and 42.4% (IPF Cachexia Syndrome). Cachectic patients showed significantly lower muscle mass, function, and quality (measured by reduced muscle attenuation at T12-CT), along with higher GDF-15 and lower PGC-1α levels. The presence of IPF Cachexia syndrome (HR 2.56; 95% CI, 1.08–6.07; p = 0.033), GDF-15 > 4412.0 pg/mL (HR 3.21; 95% CI, 1.04–9.90; p = 0.042) and impaired TUG (>8 s) (HR 3.77; 95% CI, 1.63–8.71; 0.002) were all independently associated with increased 24-month mortality. Conclusions: Cachexia is prevalent in IPF and showed strong concordance between the three diagnostic criteria. The IPF Cachexia syndrome, based on comprehensive morphofunctional phenotyping, demonstrated superior discriminatory capacity. The addition of mitochondrial biomarkers may improve early detection and support personalized interventions to improve patient outcomes.
  • Etiology of tricuspid regurgitation and mortality: a multicenter cohort study
    Jorge Rodríguez-Capitán, Paloma Márquez-Camas, Jesús Carmona-Carmona, Diego Félix Arroyo Moñino, Marinela Chaparro-Muñoz, Matías Soler-González, Manuel García del Río, Teodora Egido de la Iglesia, Jorge Segovia-Reyes, Mora Murri, José Raúl López Salguero, David Couto-Mallón, Miguel Romero-Cuevas, Francisco Javier Pavón-Morón, Mario Gutiérrez-Bedmar, Manuel Jiménez-Navarro
    Clinical Research in Cardiology, 2025
    Background Significant tricuspid regurgitation (TR) encompasses a wide range of etiologies, complicating a comprehensive understanding of disease progression and prognostic factors. This study aimed to assess mortality associated with significant TR, focusing on the role of valvular disease etiology and other predictive factors. Methods This is a retrospective, multicenter, cohort observational study, including all consecutive patients with moderate-to-severe or greater TR. The patients were classified into five etiological groups: organic TR, TR secondary to left valvulopathy, TR secondary to left or right ventricular dysfunction, TR secondary to pulmonary hypertension, and atrial TR. The long-term mortality was assessed (median follow-up: 39.8 months). Results 757 patients were included. The overall mortality incidence rate was 162.5 deaths per 1000 patient-years. Compared to atrial TR, all other etiologies presented a higher mortality risk: organic TR adjusted hazard ratio (aHR) = 2.344 (95% confidence interval [CI]: 1.138–4.829), left valvulopathy-related TR aHR = 1.901 (95% CI: 1.011–3.574), ventricular dysfunction-related TR aHR = 3.683 (95% CI: 1.627–8.338), and pulmonary hypertension-related TR aHR = 2.446 (95% CI: 1.215–4.927). In addition to known factors, male sex was associated with a higher mortality risk (aHR = 1.608, 1.175–2.201), while beta-blocker use was linked to a lower risk (aHR = 0.674, 0.502–0.904). Conclusions In a large cohort of patients with significant TR, and after adjusting for clinical and echocardiographic variables, all etiological groups exhibited a higher mortality risk compared to atrial TR. Additionally, male patients with TR had a higher mortality risk, while beta-blocker therapy emerged as a protective factor.
  • Cluster sets and traditional sets elicit similar muscular hypertrophy: a volume and effort-matched study in resistance-trained individuals
    Salvador Vargas-Molina, Manuel García-Sillero, Sergio Maroto-Izquierdo, Eneko Baz-Valle, Borja Bautista-Mayorga, Mora Murri, Brad J. Schoenfeld, Javier Benítez-Porres
    European Journal of Applied Physiology, 2025
    Background and Objective Previous studies examining the effects of cluster sets (CS) compared to traditional sets (TS) protocols on muscle hypertrophy have primarily equated to volume load. This inevitably has resulted in a lower number of repetitions performed in TS compared to CS, thereby leading to a suboptimal hypertrophic stimulus. The present study aimed to compare the impact of CS and TS protocols, both performed with the same number of sets and repetitions, but with loads adjusted to the same range of repetitions in reserve (RIR) on muscle hypertrophy. Methods Ten resistance-trained volunteers (7 men and 3 women, 21.0 ± 1.5 years, 64.3 ± 6.9 kg, and 169.3 ± 6.2 cm) participated in this study. Participants performed two training protocols over an 8-week period, with two weekly sessions consisting of 5 sets of 12 repetitions of the leg press and leg extension exercises. The study employed a within-participant, unilateral design where one limb performed a TS protocol and the contralateral limb performed 3 clusters of 4 repetitions with a 20-s intra-set rest period of the same exercises (CS). Muscle thickness was assessed via ultrasound and thigh lean tissue mass was assessed by dual-energy X-ray absorptiometry pre- and post-study. Results Results showed similar increases in muscle thickness (p < 0.001, ES = 0.56, and p = 0.012, ES = 0.42, respectively) and lean tissue mass (p = 0.002, ES = 0.11, and p < 0.001, ES = 0.13, respectively) in both CS and TS conditions. Conclusion In conclusion, when sets, repetitions, and load adjustments were equalized based on RIR, a CS protocol elicits similar increases in muscle thickness and lean mass compared to a TS protocol.
  • The Nutritional Phenotyping of Idiopathic Pulmonary Fibrosis Through Morphofunctional Assessment: A Bicentric Cross-Sectional Case–Control Study
    Alicia Sanmartín-Sánchez, Rocío Fernández-Jiménez, Eva Cabrera-César, Francisco Espíldora-Hernández, Isabel Vegas-Aguilar, María del Mar Amaya-Campos, Fiorella Ximena Palmas-Candia, Josefina Olivares-Alcolea, Víctor José Simón-Frapolli, Isabel Cornejo-Pareja, Ana Sánchez-García, Mora Murri, Patricia Guirado-Peláez, Álvaro Vidal-Suárez, Lourdes Garrido-Sánchez, Francisco J. Tinahones, Jose Luis Velasco-Garrido, Jose Manuel García-Almeida
    Life, 2025
    There is increasing evidence supporting the use of morphofunctional assessment (MFA) as a tool for clinical characterization and decision-making in malnourished patients. MFA enables the diagnosis of malnutrition, sarcopenia, obesity, and cachexia, leading to a novel phenotype-based classification of nutritional disorders. Bioelectrical impedance analysis (BIVA), nutritional ultrasound® (NU) and computed tomography (CT) are included, along with functional tests like the Timed Up and Go test (TUG). Myoesteatosis, detectable via CT, can occur independently from nutritional phenotypes and has been identified as a significant mortality predictor in idiophatic pulmonary fibrosis (IPF). Our aim is to analyze the prevalence and overlap of nutritional phenotypes in IPF and evaluate the prognostic value of myoesteatosis. Our bicenter cross-sectional study included 82 IPF patients (84.1% male and with a medium age of 71.1 ± 7.35 years). MFA was performed using BIVA, NU, CT at the T12 level (CT-T12), the handgrip strength (HGS) test, and the TUG. CT-T12 BC parameters were analyzed using FocusedON® software, while statistical analyses were conducted with JAMOVI version 2.3.22. All four major nutritional phenotypes were represented in our cohort, with significant overlap. A total of 80.5% met the GLIM criteria for malnutrition, 14.6% had cachexia, 17% were sarcopenic, and 28% were obese. Of the obese patients, 70% were also malnourished, while 100% of sarcopenic obese patients (5.9% of total) had malnutrition. A total of 55% of sarcopenic patients with available CT also had myosteatosis, suggesting muscle quality deterioration as a potential driver of functional impairment. The presence of myosteatosis > 15% in T12-CT was an independent predictor of 12-month mortality (HR = 3.13; 95% CI: 1.01–9.70; p = 0.049), with survival rates of 78.1% vs. 96.6% in patients with vs. without myosteatosis, respectively. To conclude, this study underscores the relevance of MFA in the nutritional characterization of patients with IPF, demonstrating its potential to identify specific phenotypes associated with malnutrition, functional impairment, and the presence of myoesteatosis, thereby providing a valuable tool for clinical decision-making.
  • Neutrophils as indicators of obesity-associated inflammation: A systematic review and meta-analysis
    Gema Gomez‐Casado, Andres Jimenez‐Gonzalez, Alba Rodriguez‐Muñoz, Francisco J. Tinahones, Ernesto González‐Mesa, Mora Murri, Almudena Ortega‐Gomez
    Obesity Reviews, 2025
    SummaryIntroductionThe aim of this study is to evaluate and compare the suitability of routine blood neutrophil values as indicators of obesity‐associated inflammation.MethodsIn this systematic review and meta‐analysis, we assess absolute neutrophil counts (ANCs) and neutrophil‐to‐lymphocyte ratio (NLR) values in subjects with and without obesity and analyze the weight of both parameters on the disease. Additionally, correlation studies between ANC and NLR with BMI, a parameter internationally accepted to define obesity are performed.ResultsQuantitative data from 12 (ANC) and 11 (NLR) studies were included, with a total of 4475 participants. The meta‐analysis shows that while both parameters are increased in the obesity group, ANC values present higher differences with the control and less heterogeneity among studies. Additionally, unlike NLR, ANC demonstrates a positive and significant correlation with BMI.ConclusionOverall, this meta‐analysis demonstrates that ANC is a more reliable and stable parameter than NLR for the assessment of obesity‐related inflammation, which offers clinicians a novel tool to assist in preventing complications related to obesity.
  • Editorial: Diet and training strategies to optimize health parameters
    Javier Benítez-Porres, Mora Murri
    Frontiers in Public Health, 2025
    Recent changes in dietary patterns have contributed to rising rates of malnutrition and diet-related chronic diseases. Zheng et al. (2024) found that healthy low-carbohydrate and low-fat diets reduced the risk of adiposity. Similarly, Zu et al. (2024) showed that higher dietary intake of flavonoids significantly reduced weight-adjusted waist index (WWI). Encouraging the consumption of flavonoid-rich foods to reduce obesity and related chronic diseases. These findings underscore the need for population-based interventions to promote healthier diets and reduce disease risk.Mental health also intersects with dietary behaviors in meaningful ways. Jin et al. (2024) linked depressive symptoms during pregnancy to impaired intuitive eating behaviors and poorer diet quality, emphasizing the need to integrate mental health support with nutrition education. Tokarek et al. (2023) further explored the role of personality traits, finding that neuroticism may led to poorer dietary choices, while conscientiousness was associated with healthier behaviors. Personality-driven interventions, such as stress management workshops and mindfulness-based interventions, can promote resilience and healthier habits in high-stress environments.Physical activity plays a pivotal role in preventing psychiatric, neurological, metabolic, cardiovascular, pulmonary, and musculoskeletal diseases, as well as cancer (Lindblom et al., 2021). Evidence consistently shows that higher levels of physical activity and reduced sedentary behavior lower all-cause mortality, particularly in middle-aged and older adults. Moderate-to-vigorous physical activity also reduces hospitalization risk from conditions like cardiovascular diseases. Onofrei et al. ( 2024) found that nurses with chronic conditions experienced higher stress levels, poorer health perception, and higher BMI, along with greater carbohydrate consumption. These findings underline the need for workplace wellness programs addressing mental health, nutrition, and physical activity. Healthcare professionals, often caught in high-stress environments, require targeted interventions to mitigate these risks.Urban environments significantly influence chronic diseases prevalence. Irankhah et al. (2024) revealed that improving urban infrastructure and reducing socioeconomic disparities could lower NCD risks. Access to parks, pedestrian-friendly spaces, and affordable nutritious foods fosters healthier communities. Policy makers should prioritize creating environments conducive to healthy living. Socioeconomic factors also play a pivotal role. Areba et al. ( 2024) identified education and employment as key determinants of food security among pregnant women. The researchers, emphasizing systemic interventions to address structural issues. Policies empowering women through education and economic opportunities can improve household food security and maternal and child health. Wang et al. (2023) demonstrated that adherence to the American Heart Association's Life's Simple 7 (LS7) health guidelines reduced rheumatoid arthritis (RA) risk, particularly among men under 50 and women across all age groups. This highlights the importance of early and consistent lifestyle changes, including maintaining a healthy weight, regular physical activity, and balanced diets. Gender-specific messaging can further enhance public health initiatives.Integrating dietary and physical activity interventions within broader policy frameworks is essential for sustainable health outcomes. Enhancing food literacy (Zhixue et al., 2024) helps bridge the gap between awareness and action, while global efforts to regulate food marketing and reduce sugar consumption complement local community-specific programs addressing unique cultural and socioeconomic determinants of health.The interplay between diet, physical activity, mental health, and social determinants forms the foundation of effective interventions. By addressing these interconnected factors, we can create holistic strategies that not only reduce NCD prevalence but also enhance overall quality of life.Addressing NCDs requires a dual approach: tackling global challenges while tailoring interventions to local contexts. Globally, collaborative efforts are needed to regulate food marketing, reduce sugar consumption, and promote physical activity through international campaigns. Locally, community-specific programs can address unique cultural, economic, and social determinants of health.Future research should focus on evaluating the long-term impact of combined dietary and physical activity interventions. Policymakers, healthcare professionals, and community leaders must collaborate to implement evidence-based solutions, ensuring accessibility and sustainability. Together, these efforts can pave the way for healthier individuals, communities, and nations.
  • Circulating PGC-1α and MOTS-c Peptide as Potential Mitochondrial Biomarkers in Patients Undergoing Aortic Valve Replacement
    María Sánchez-Quintero, Andrea Iboleón, Laura Martín Chaves, Bárbara Pozo Vilumbrales, Ada Carmona-Segovia, Pilar Martínez López, Miguel Romero-Cuevas, Jorge Rodríguez-Capitán, Víctor Becerra-Muñoz, Francisco Javier Pavón-Morón, Mora Murri
    Biologics Targets and Therapy, 2025
    Purpose Aortic valve disease (AVD) is a common condition that leads to pressure and/or volume overload in the left ventricle. Aortic valve replacement is the standard treatment, as no pharmacological therapies are currently available. The incidence of AVD is increasing in developed countries, making the discovery of new biomarkers for early detection crucial. The importance of mitochondria in heart function is well established, and various cardiovascular pathologies are associated with mitochondrial dysfunction. In this cross-sectional study, we evaluated for the first time the role of mitochondria in AVD, aiming to identify new pathways involved in the disease and discover potential biomarkers. Patients and Methods We recruited 17 patients diagnosed with AVD and scheduled for aortic valve replacement, and 22 healthy controls. Plasma levels of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) and mitochondrial open reading frame of the 12S rRNA type-c peptide (MOTS-c) were measured by ELISA. Results We observed significantly reduced levels of both proteins in patients, suggesting that substantial mitochondrial dysfunction occurs in AVD patients, independent of sex or age, but directly related to the disease. Conclusion Mitochondria may represent a promising target for studying new pathways involved in AVD. We propose PGC1α and MOTS-c as potential plasma biomarkers for AVD detection. Further studies, including early-stage patients, are necessary to confirm the significance of our findings.
  • Distinct cytokine profiles in plasma and tears highlight ophthalmologic inflammation in type 2 diabetes without retinopathy
    Rafael Jiménez-López, Laura Martín-Chaves, Ángel Manuel Gutiérrez-García, Ada del Mar Carmona-Segovia, Begoña Mora-Ordoñez, Ana María Sánchez-García, Lourdes Fernández-Romero, Mora Murri, María José Sánchez-Quintero, Germán Berteli-García, Miguel Ángel Sánchez-Chaparro, Vicente Bodí, Jorge Rodríguez-Capitán, Manuel Jiménez-Navarro, Francisco Javier Pavón-Morón, José Lorenzo Romero-Trevejo
    Frontiers in Medicine, 2025
  • A Systematic Review of Proteomics in Obesity: Unpacking the Molecular Puzzle
    Alba Rodriguez-Muñoz, Hanieh Motahari-Rad, Laura Martin-Chaves, Javier Benitez-Porres, Jorge Rodriguez-Capitan, Andrés Gonzalez-Jimenez, Maria Insenser, Francisco J. Tinahones, Mora Murri
    Current Obesity Reports, 2024
  • Correction to: A Systematic Review of Proteomics in Obesity: Unpacking the Molecular Puzzle (Current Obesity Reports, (2024), 13, 3, (403-438), 10.1007/s13679-024-00561-4)
    Alba Rodriguez-Muñoz, Hanieh Motahari-Rad, Laura Martin-Chaves, Javier Benitez-Porres, Jorge Rodriguez-Capitan, Andrés Gonzalez-Jimenez, Maria Insenser, Francisco J. Tinahones, Mora Murri
    Current Obesity Reports, 2024
  • IA-Body Composition CT at T12 in Idiopathic Pulmonary Fibrosis: Diagnosing Sarcopenia and Correlating with Other Morphofunctional Assessment Techniques
    Rocío Fernández-Jiménez, Alicia Sanmartín-Sánchez, Eva Cabrera-César, Francisco Espíldora-Hernández, Isabel Vegas-Aguilar, María del Mar Amaya-Campos, Fiorella Ximena Palmas-Candia, María Claro-Brandner, Josefina Olivares-Alcolea, Víctor José Simón-Frapolli, Isabel Cornejo-Pareja, Patricia Guirado-Peláez, Álvaro Vidal-Suárez, Ana Sánchez-García, Mora Murri, Lourdes Garrido-Sánchez, Francisco J. Tinahones, Jose Luis Velasco-Garrido, Jose Manuel García-Almeida
    Nutrients, 2024
  • Sex-based Differences in Heart Failure Biomarkers
    Ainhoa Robles-Mezcua, Nelsa González Aguado, Antonia Pilar Martin de la Rosa, Concepción Cruzado-Álvarez, Clara Jiménez Rubio, Alejandro IPérez Cabeza, Juan José Gómez-Doblas, Manuel F. Jiménez-Navarro, Mora Murri Pierri, José M. García-Pinilla
    Current Heart Failure Reports, 2024
  • Differential Ophthalmological Profile in Patients with Coronary Artery Disease Coexisting with Type 2 Diabetes Mellitus: Elevated Tear Cytokine Concentrations
    Rafael Jiménez-López, José Lorenzo Romero-Trevejo, Lourdes Fernández-Romero, Laura Martín-Chaves, Miguel Romero-Cuevas, Ana Isabel Molina-Ramos, María José Sánchez-Quintero, Mora Murri, Francesco Costa, Vicente Bodí, Mario Gutiérrez-Bedmar, Jorge Rodríguez-Capitán, Francisco Javier Pavón-Morón, Manuel Jiménez-Navarro
    Journal of Clinical Medicine, 2024
  • Effects of the Ketogenic Diet on Strength Performance in Trained Men and Women: A Systematic Review and Meta-Analysis
    Salvador Vargas-Molina, Mora Murri, Andrés Gonzalez-Jimenez, José Luis Gómez-Urquiza, Javier Benítez-Porres
    Nutrients, 2024
  • Glycaemic Response to Acute Aerobic and Anaerobic Exercise Performed in the Morning or Afternoon in Healthy Subjects: A Crossover Trial
    Alba Rodriguez-Muñoz, José Ignacio Martínez-Montoro, Belen Sojo-Rodriguez, Javier Benitez-Porres, Margarita Carrillo-Albornoz-Gil, Laura Carrasco-Fernandez, Alba Subiri-Verdugo, Ana Molina-Ramos, Andrés Cobos-Diaz, Francisco J. Tinahones, Almudena Ortega-Gomez, Mora Murri
    Journal of the International Society of Sports Nutrition, 2024
  • Rectus femoris cross sectional area and timed up and go test potential useful of as a predictor of sarcopenia and mortality in idiopathic pulmonary fibrosis
    Rocío Fernández-Jiménez, Eva Cabrera-Cesar, Alicia Sanmartín-Sánchez, Ana Sánchez-Garcia, Francisco Espildora-Hernandez, Isabel Vegas-Aguilar, Maria del Mar Amaya-Campos, Patricia Guirado-Pelaez, Victor Simón-Frapolli, Mora Murri, Lourdes Garrido-Sánchez, Lorena Piñel-Jimenez, Miguel Benítez Cano-Gamonoso, Javier López-García, Belén Gómez-Rodríguez, Jose Luis Velasco-Garrido, Francisco J. Tinahones, José Manuel García-Almeida
    Frontiers in Nutrition, 2024
  • Physical activity shifts gut microbiota structure in aged subjects with overweight/obesity and metabolic syndrome
    Patricia Ruiz-Limón, Jananee Muralidharan, Ana M. Gomez-Perez, Mora Murri, Jesús Vioque, Dolores Corella, Montse Fitó, Josep Vidal, Jordi Salas-Salvadó, Laura Torres-Collado, Oscar Coltell, Alessandro Atzeni, Olga Castañer, Mònica Bulló, M. Rosa Bernal-López, Isabel Moreno-Indias, Francisco J. Tinahones
    Biology of Sport, 2024
  • Effects of exercise timing on metabolic health
    José Ignacio Martínez‐Montoro, Javier Benítez‐Porres, Francisco J. Tinahones, Almudena Ortega‐Gómez, Mora Murri
    Obesity Reviews, 2023
  • Rectus Femoris Cross-Sectional Area and Phase Angle asPredictors of 12-Month Mortality in Idiopathic Pulmonary Fibrosis Patients
    Rocío Fernández-Jiménez, Eva Cabrera Cesar, Ana Sánchez García, Francisco Espíldora Hernández, Isabel M. Vegas-Aguilar, Maria del Mar Amaya-Campos, Isabel Cornejo-Pareja, Patricia Guirado-Peláez, Victor Simón-Frapolli, Mora Murri, Lourdes Garrido-Sánchez, Alvaro Martínez Mesa, Lorena Piñel-Jimenez, Miguel Benítez-Cano Gamonoso, Lara Dalla-Rovere, Maria García Olivares, Jose Luis Velasco-Garrido, Francisco Tinahones-Madueño, José Manuel García-Almeida
    Nutrients, 2023
  • Multi-Omics Approach Reveals Prebiotic and Potential Antioxidant Effects of Essential Oils from the Mediterranean Diet on Cardiometabolic Disorder Using Humanized Gnotobiotic Mice
    María José Sánchez-Quintero, Josué Delgado, Laura Martín Chaves, Dina Medina-Vera, Mora Murri, Víctor M. Becerra-Muñoz, Mario Estévez, María G. Crespo-Leiro, Guillermo Paz López, Andrés González-Jiménez, Juan A. G. Ranea, María Isabel Queipo-Ortuño, Isaac Plaza-Andrades, Jorge Rodríguez-Capitán, Francisco Javier Pavón-Morón, Manuel F. Jiménez-Navarro
    Antioxidants, 2023
  • Choroidal thickness and granulocyte colony-stimulating factor in tears improve the prediction model for coronary artery disease
    José Lorenzo Romero-Trevejo, Lourdes Fernández-Romero, Josué Delgado, Erika Muñoz-García, Andrés Sánchez-Pérez, Mora Murri, Mario Gutiérrez-Bedmar, Manuel Francisco Jiménez-Navarro
    Cardiovascular Diabetology, 2022
  • Mitochondrial Homeostasis in Obesity-related Hypertriglyceridemia
    Virginia Mela, Patricia Ruiz-Limón, Manuel Balongo, Hanieh Motahari Rad, Alba Subiri-Verdugo, Andres Gonzalez-Jimenez, Rocio Soler, Luis Ocaña, Hamid el Azzouzi, Francisco J Tinahones, Pedro Valdivielso, Mora Murri
    Journal of Clinical Endocrinology and Metabolism, 2022
  • The Effect of Sex and Obesity on the Gene Expression of Lipid Flippases in Adipose Tissue
    Hanieh Motahari-Rad, Alba Subiri, Rocio Soler, Luis Ocaña, Juan Alcaide, Jorge Rodríguez-Capitan, Veronica Buil, Hamid el Azzouzi, Almudena Ortega-Gomez, Rosa Bernal-Lopez, Maria Insenser, Francisco J. Tinahones, Mora Murri
    Journal of Clinical Medicine, 2022
  • Evaluation of Adipose Tissue Zinc-Alpha 2-Glycoprotein Gene Expression and Its Relationship with Metabolic Status and Bariatric Surgery Outcomes in Patients with Class III Obesity
    José Ignacio Martínez-Montoro, Luis Ocaña-Wilhelmi, Rocío Soler-Humanes, Hanieh Motahari-Rad, Andrés González-Jiménez, José Rivas-Becerra, Alba Rodríguez-Muñoz, Francisco J. Moreno-Ruiz, Mónica Tomé, Jorge Rodríguez-Capitán, Eduardo García-Fuentes, Francisco J. Tinahones, Lourdes Garrido-Sánchez, Mora Murri
    Biomedicines, 2022
  • Molecular Changes in the Adipose Tissue Induced by Rheumatoid Arthritis: Effects of Disease-Modifying Anti-Rheumatic Drugs
    Iván Arias de la Rosa, Alejandro Escudero-Contreras, Miriam Ruiz-Ponce, Cristóbal Román-Rodríguez, Carlos Pérez-Sánchez, María del Carmen Ábalos-Aguilera, Rafaela Ortega-Castro, Juan Alcaide, Mora Murri, Pilar Font, Jerusalem Calvo-Gutiérrez, Maria Luque-Tevar, Alejandra Maria Patiño-Trives, Rocío Guzmán-Ruiz, Maria del Mar Malagón, Francisco José Tinahones, Eduardo Collantes-Estévez, Chary López-Pedrera, Nuria Barbarroja
    Frontiers in Immunology, 2021
  • Editorial: Emerging Roles of the Gut Microbiota in the Pathogenesis of Metabolic Disorders
    Isabel Moreno-Indias, Antonio Salgado-Somoza, Hamid el Azzouzi, Mora Murri
    Frontiers in Endocrinology, 2021
  • Visceral Adipose Tissue Phospholipid Signature of Insulin Sensitivity and Obesity
    Magalí Palau-Rodriguez, Anna Marco-Ramell, Patricia Casas-Agustench, Sara Tulipani, Antonio Miñarro, Alex Sanchez-Pla, Mora Murri, Francisco J. Tinahones, Cristina Andres-Lacueva
    Journal of Proteome Research, 2021
  • Chapter 9: Proteomics in Nutrition, Obesity and Diabetes Research
    P. Ruiz-Limon, M. Balongo, M. Insenser, F. J. Tinahones, M. Murri
    Food Chemistry Function and Analysis, 2021
  • A year in the life of the EU-CardioRNA COST action: CA17129 catalysing transcriptomics research in cardiovascular disease
    Emma Louise Robinson, Clarissa Pedrosa da Costa Gomes, Ines Potočnjak, Jan Hellemans, Fay Betsou, David de Gonzalo-Calvo, Monika Stoll, Mehmet Birhan Yilmaz, Bence Ágg, Dimitris Beis, Maria Carmo-Fonseca, Francisco J. Enguita, Soner Dogan, Bilge G. Tuna, Blanche Schroen, Wim Ammerlaan, Gabriela M. Kuster, Irina Carpusca, Thierry Pedrazzini, Costanza Emanueli, Fabio Martelli, Yvan Devaux
    Non Coding RNA, 2020
  • MiR-337-3p Promotes Adipocyte Browning by Inhibiting TWIST1
    Indira G.C. Vonhögen, Hamid el Azzouzi, Servé Olieslagers, Aliaksei Vasilevich, Jan de Boer, Francisco J. Tinahones, Paula A. da Costa Martins, Leon J. de Windt, Mora Murri
    Cells, 2020
  • miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes
    Adriana‐Mariel Gentile, Said Lhamyani, Leticia Coín‐Aragüez, Mercedes Clemente‐Postigo, Wilfredo Oliva Olivera, Silvana‐Yanina Romero‐Zerbo, Sara García‐Serrano, Eva García‐Escobar, Hatem Zayed, Esther Doblado, Francisco‐Javier Bermúdez‐Silva, Mora Murri, Francisco J. Tinahones, Rajaa El Bekay
    Obesity, 2019
  • Non-targeted profiling of circulating microRNAs in women with polycystic ovary syndrome (PCOS): effects of obesity and sex hormones
    Mora Murri, María Insenser, Elena Fernández-Durán, José L. San-Millán, Manuel Luque-Ramírez, Héctor F. Escobar-Morreale
    Metabolism Clinical and Experimental, 2018
  • MicroRNAs as regulators of mitochondrial dysfunction and obesity
    Mora Murri, Hamid el Azzouzi
    American Journal of Physiology Heart and Circulatory Physiology, 2018
  • Gut microbiota and the polycystic ovary syndrome: Influence of sex, sex hormones, and obesity
    María Insenser, Mora Murri, Rosa del Campo, M Ángeles Martínez-García, Elena Fernández-Durán, Héctor F Escobar-Morreale
    Journal of Clinical Endocrinology and Metabolism, 2018
  • Plasma thiobarbituric acid reactive substances (TBARS) in young adults: Obesity increases fasting levels only in men whereas glucose ingestion, and not protein or lipid intake, increases postprandial concentrations regardless of sex and obesity
    Rafael Montes-Nieto, María Insenser, Mora Murri, Elena Fernández-Durán, Miriam Ojeda-Ojeda, María Ángeles Martínez-García, Manuel Luque-Ramírez, Héctor F. Escobar-Morreale
    Molecular Nutrition and Food Research, 2017
  • Unfavorable cytokine and adhesion molecule profiles during and after pregnancy, in women with gestational diabetes mellitus
    María del Mar Roca-Rodríguez, Cristina López-Tinoco, Álvaro Fernández-Deudero, Mora Murri, María Victoria García-Palacios, María del Amor García-Valero, Francisco José Tinahones, Manuel Aguilar-Diosdado
    Endocrinologia Diabetes Y Nutricion, 2017
  • Metabolomics in polycystic ovary syndrome
    Mora Murri, María Insenser, Héctor F. Escobar-Morreale
    Clinica Chimica Acta, 2014
  • Proteomic analysis of adipose tissue: Informing diabetes research
    Mora Murri, María Insenser, Manuel Luque, Francisco J Tinahones, Héctor F Escobar-Morreale
    Expert Review of Proteomics, 2014
  • GLP-1 and peptide YY secretory response after fat load is impaired by insulin resistance, impaired fasting glucose and type 2 diabetes in morbidly obese subjects
    José C. Fernández-García, Mora Murri, Leticia Coin-Aragüez, Juan Alcaide, Rajaa El Bekay, Francisco J. Tinahones
    Clinical Endocrinology, 2014
  • Postpartum development of endothelial dysfunction and oxidative stress markers in women with previous gestational diabetes mellitus
    M. M. Roca-Rodríguez, C. López-Tinoco, M. Murri, A. Fernández-Deudero, M. V. García-Palacios, M. A. García-Valero, F. J. Tinahones-Madueño, M. Aguilar-Diosdado
    Journal of Endocrinological Investigation, 2014
  • Effects of polycystic ovary syndrome (PCOS), sex hormones, and obesity on circulating miRNA-21, miRNA-27b, miRNA-103, and miRNA-155 expression
    Mora Murri, María Insenser, Elena Fernández-Durán, José L. San-Millán, Héctor F. Escobar-Morreale
    Journal of Clinical Endocrinology and Metabolism, 2013
  • Mediators of low-grade chronic inflammation in polycystic ovary syndrome (PCOS)
    Miriam Ojeda-Ojeda, Mora Murri, Maria Insenser, Hector Escobar-Morreale
    Current Pharmaceutical Design, 2013
  • Proteomic analysis of visceral adipose tissue in pre-obese patients with type 2 diabetes
    Mora Murri, Maria Insenser, Maria Rosa Bernal-Lopez, Pablo Perez-Martinez, Hector F. Escobar-Morreale, Francisco J. Tinahones
    Molecular and Cellular Endocrinology, 2013
  • Thymus fat as an attractive source of angiogenic factors in elderly subjects with myocardial ischemia
    Leticia Coín Aragüez, Mora Murri, Wilfredo Oliva Olivera, Julian Salas, Maria Dolores Mayas, Javier Delgado-Lista, Francisco Tinahones, Rajaa El Bekay
    Age, 2013
  • Gut Microbiota Composition in Male Rat Models under Different Nutritional Status and Physical Activity and Its Association with Serum Leptin and Ghrelin Levels
    María Isabel Queipo-Ortuño, Luisa María Seoane, Mora Murri, María Pardo, Juan Miguel Gomez-Zumaquero, Fernando Cardona, Felipe Casanueva, Francisco J. Tinahones
    Plos One, 2013
  • Proteomic and metabolomic approaches to the study of polycystic ovary syndrome
    María Insenser, Rafael Montes-Nieto, Mora Murri, Héctor F. Escobar-Morreale
    Molecular and Cellular Endocrinology, 2013
  • Circulating markers of oxidative stress and polycystic ovary syndrome (pcos): A systematic review and meta-analysis
    Mora Murri, Manuel Luque-Ramírez, María Insenser, Miriam Ojeda-Ojeda, Hector F. Escobar-Morreale
    Human Reproduction Update, 2013
  • Comparative study of microbial-derived phenolic metabolites in human feces after intake of gin, red wine, and dealcoholized red wine
    Ana Jiménez-Girón, María Isabel Queipo-Ortuño, Maria Boto-Ordóñez, Irene Muñoz-González, Fernando Sánchez-Patán, Maria Monagas, Pedro J. Martín-Álvarez, Mora Murri, Francisco J. Tinahones, Cristina Andrés-Lacueva, Begoña Bartolomé, M.Victoria Moreno-Arribas
    Journal of Agricultural and Food Chemistry, 2013
  • Oxidative stress and antioxidant status in patients with late-onset gestational diabetes mellitus
    Cristina López-Tinoco, Mar Roca, Amor García-Valero, Mora Murri, Francisco J. Tinahones, Carmen Segundo, José L. Bartha, Manuel Aguilar-Diosdado
    Acta Diabetologica, 2013
  • Particular characteristics of the metabolic syndrome in patients with morbid obesity
    Francisco J. Tinahones, Lourdes Garrido-Sánchez, Mora Murri, Eduardo García-Fuentes, Fernando Cardona
    Endocrinologia Y Nutricion, 2013
  • Caspase induction and BCL2 inhibition in human adipose tissue
    Francisco José Tinahones, Leticia Coín Aragüez, Mora Murri, Wilfredo Oliva Olivera, María Dolores Mayas Torres, Nuria Barbarroja, Ricardo Gomez Huelgas, Maria M. Malagón, Rajaa El Bekay
    Diabetes Care, 2013
  • Gut microbiota in children with type 1 diabetes differs from that in healthy children: A case-control study
    Mora Murri, Isabel Leiva, Juan Miguel Gomez-Zumaquero, Francisco J Tinahones, Fernando Cardona, Federico Soriguer, María Isabel Queipo-Ortuño
    BMC Medicine, 2013
  • Cellular and plasma oxidative stress biomarkers are raised in adults with bronchiectasis
    Gabriel Olveira, Casilda Olveira, Antonio Dorado, Eduardo García-Fuentes, Elehazara Rubio, Francisco Tinahones, Federico Soriguer, Mora Murri
    Clinical Nutrition, 2013
  • Adipokines and metabolic syndrome risk factors in women with previous gestational diabetes mellitus
    M. Mar Roca‐Rodríguez, Cristina López‐Tinoco, Álvaro Fernández‐Deudero, Mora Murri, María Victoria García‐Palacios, M. Amor García‐Valero, Francisco J. Tinahones‐Madueño, Manuel Aguilar‐Diosdado
    Diabetes Metabolism Research and Reviews, 2012
  • Hemoglobin A 1c versus oral glucose tolerance test in postpartum diabetes screening
    María José Picón, Mora Murri, Araceli Muñoz, José Carlos Fernández-García, Ricardo Gomez-Huelgas, Francisco J. Tinahones
    Diabetes Care, 2012
  • Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers
    María Isabel Queipo-Ortuño, María Boto-Ordóñez, Mora Murri, Juan Miguel Gomez-Zumaquero, Mercedes Clemente-Postigo, Ramon Estruch, Fernando Cardona Diaz, Cristina Andrés-Lacueva, Francisco J Tinahones
    American Journal of Clinical Nutrition, 2012
  • Endotoxin increase after fat overload is related to postprandial hypertriglyceridemia in morbidly obese patients
    M. Clemente-Postigo, M.I. Queipo-Ortuño, M. Murri, M. Boto-Ordoñez, P. Perez-Martinez, C. Andres-Lacueva, F. Cardona, F.J. Tinahones
    Journal of Lipid Research, 2012
  • Bypass of the duodenum improves insulin resistance much more rapidly than sleeve gastrectomy
    L. Garrido-Sanchez, M. Murri, J. Rivas-Becerra, L. Ocaña-Wilhelmi, R.V. Cohen, E. Garcia-Fuentes, F.J. Tinahones
    Surgery for Obesity and Related Diseases, 2012
  • Continuous positive airway pressure therapy reduces oxidative stress markers and blood pressure in sleep apnea-hypopnea syndrome patients
    Mora Murri, Regina García-Delgado, José Alcázar-Ramírez, Luis Fernández de Rota, Ana Fernández-Ramos, Fernando Cardona, Francisco J. Tinahones
    Biological Trace Element Research, 2011
  • Effect of CPAP on oxidative stress and circulating progenitor cell levels in sleep patients with apnea-hypopnea syndrome
    Mora Murri, Regina García-Delgado, José Alcázar-Ramírez, Ana Fernández-Ramos, Juan Alcaide, Fernando Cardona, Francisco J Tinahones
    Respiratory Care, 2011
  • Assessment of cellular and plasma oxidative stress in SAHS patients before and after continuous positive airway pressure treatment
    Clinical Laboratory, 2010
  • PPARγ expression after a high-fat meal is associated with plasma superoxide dismutase activity in morbidly obese persons
    Eduardo Garcia‐Fuentes, Mora Murri, Lourdes Garrido‐Sanchez, Sara Garcia‐Serrano, Jose M. García‐Almeida, Inmaculada Moreno‐Santos, Francisco J. Tinahones, Manuel Macias‐Gonzalez
    Obesity, 2010
  • Fat overload induces changes in circulating lactoferrin that are associated with postprandial lipemia and oxidative stress in severely obese subjects
    José M. Fernández‐Real, Eduardo García‐Fuentes, José M. Moreno‐Navarrete, Mora Murri‐Pierri, Lourdes Garrido‐Sánchez, Wifredo Ricart, Francisco Tinahones
    Obesity, 2010
  • Changes in oxidative stress and insulin resistance in morbidly obese patients after bariatric surgery
    Mora Murri, Eduardo García-Fuentes, José Manuel García-Almeida, Lourdes Garrido-Sánchez, María Dolores Mayas, Rosa Bernal, Francisco J. Tinahones
    Obesity Surgery, 2010
  • The -1131T>C SNP of the APOA5 gene modulates response to fenofibrate treatment in patients with the metabolic syndrome: A postprandial study
    Fernando Cardona, Montserrat Guardiola, María Isabel Queipo-Ortuño, Mora Murri, Josep Ribalta, Francisco J. Tinahones
    Atherosclerosis, 2009
  • Oxidative stress in severely obese persons is greater in those with insulin resistance
    Francisco J. Tinahones, Mora Murri‐Pierri, Lourdes Garrido‐Sánchez, Jose M. García‐Almeida, Sara García‐Serrano, Juan García‐Arnés, Eduardo García‐Fuentes
    Obesity, 2009
  • Oxidative stress and metabolic changes after continuous positive airway pressure treatment according to previous metabolic disorders in sleep apnea-hypopnea syndrome patients
    Mora Murri, José Alcázar-Ramírez, Lourdes Garrido-Sánchez, Francisco Linde, Juan Alcaide, Fernando Cardona, Francisco J. Tinahones
    Translational Research, 2009
  • Similar increase in oxidative stress after fat overload in persons with baseline hypertriglyceridemia with or without the metabolic syndrome
    F. Cardona, I. Tunez, I. Tasset, M. Murri, F.J. Tinahones
    Clinical Biochemistry, 2008