Prof. D.P. Rao has completed twenty-two years of working in different capacities as a professor, associate professor, and assistant professor in these years. He accomplished a sponsored trip to Shenzhen, China, in November 2011 and Athens, Greece, in July 2014 by UGC New Delhi, India. He has completed 04 Research Projects along with 02 ongoing major research Projects, which have expeditious to the uplift of society in a well-defined manner. He has published 77 research papers, of which 45 are in SCI Journals. Regarding the top-cited and highly impact factor publication, one paper is credited to his account in 37 JCR Impact Factor. He has 10 patents to his credit, of which 06 are UK and 04 are Indian. At present, he is serving as Editor-in-Chief of GRS Journal of Multidisciplinary Research and Studies, International Research Journal of Scientific Reports and Reviews, and Journal of Medical Studies and Applied Sciences. He has been awarded as Best Researcher by CSJM University, Kanpur.
Enhanced photodegradation of ciprofloxacin by Cu-doped spinel ferrite nanoparticles: synthesis, characterization and mechanistic insights Cumali Celik, Aseel A. Kadhem, Muhammad Muntazir Mehdi, Dharmesh Sur, Suhas Ballal, Bilakshan Purohit, Subhashree Ray, Naveen Chandra Talniya, Devendra Pratap Rao, Ahmad Mohammad Salamatullah, Muhammad Yasar Journal of Sol Gel Science and Technology, 2026 This study introduces CuxSr1-xAl0.4Fe1.6O4 (X = 0, 0.4) as a novel photocatalyst synthesized via the sol-gel method for ciprofloxacin degradation in water systems. This composition, which combines strontium, aluminum, and copper in a spinel ferrite structure, represents a significant advancement in antibiotic remediation technology. Key findings reveal that copper doping decreased the bandgap from 2.8 to 2.6 eV, increased surface area by 38% (from 31 to 43 m2/g), and dramatically enhanced photocatalytic performance. The Cu-doped catalyst achieved 100% ciprofloxacin degradation within 75 min under optimized conditions of pH 7, 30 °C, 10 mg catalyst dosage, and 10 ppm ciprofloxacin concentration, with a second-order rate constant of 0.00756 L mg−1 min−1 under visible light irradiation (100 mW/cm2)., compared to only 54% for the undoped material. Hydroxyl radicals were identified as the primary reactive species, with degradation following second-order kinetics. The catalyst maintained over 94% efficiency after recycling five times, demonstrating its excellent stability. With superior quantum yield (3.21 × 10⁻⁶ molecules/photon) and minimal catalyst dosage requirements, this material offers a sustainable solution for the remediation of pharmaceutical contaminants. The findings have significant potential for implementation in pharmaceutical wastewater treatment plants and water purification systems.
Synthesis and Anticancer Evaluation of Methoxy-Substituted Chalcone Hybrids: DFT, Molecular Docking, and ADME Studies Anil Kumar Gautam, Saurabh Kumar, Mirtunjai Mishra, Pranjali Mishra, Shama Parveen, Monisha Banerjee, Mohiuddin Ansari, Huda Khanam, Rohit Kumar Maurya, Minshu Prashant, Hardesh K. Maurya, Yashveer Gautam, Devendra Pratap Rao, Amit Kumar Gautam, Anoop Kumar Gupta Chemistryselect, 2026 In this study, two chalcone derivatives (E)‐3‐(6‐methoxybenzo[d][1,3]dioxol‐5‐yl)‐1‐(3,4,5‐trimethoxyphenyl)prop‐2‐en‐1‐one ( SM3 ) and (E)‐1‐(3,4‐dimethoxyphenyl)‐3‐(6‐methoxybenzo[d][1,3]dioxol‐5‐yl)prop‐2‐en‐1‐one ( SM4 ), were designed based on Combretastatin A‐2 and A‐4 and evaluated for anticancer activity against human cervical cancer (SiHa) cells. Both compounds were synthesized via Claisen–Schmidt condensation of a sesamol‐derived aldehyde with substituted aryl ketones in methanolic KOH at room temperature and characterized by 1 H NMR, 1 3 C NMR, IR, and mass spectrometry. Cytotoxicity studies using the MTT assay showed dose‐dependent inhibition, where the compounds exhibited moderate activity, with IC 50 values of 48 µM ( SM3 ) and 41 µM ( SM4 ), using cisplatin as a positive control. Morphological analysis indicated membrane disruption in treated cells, while both compounds showed low toxicity (≥100 µM) toward the HEK cell line. DFT calculations (B3LYP/6‐311G(d,p)) revealed higher chemical reactivity for SM3 due to its lower HOMO–LUMO gap, whereas Natural Bond Orbital (NBO) analysis suggested greater charge delocalization in SM4, correlating with its relatively better biological performance. Molecular docking against tubulin (PDB ID: 1SA0) showed strong binding affinities for SM3 (−8.091 kcal/mol) and SM4 (−8.007 kcal/mol). ADME analysis indicated favorable drug‐like properties. Overall, SM3 and SM4 represent promising scaffolds for further development as microtubule‐targeting anticancer agents.
Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation Mohammad Chehelgerdi, Matin Chehelgerdi, Omer Qutaiba B. Allela, Renzon Daniel Cosme Pecho, Narayanan Jayasankar, Devendra Pratap Rao, Tamilanban Thamaraikani, Manimaran Vasanthan, Patrik Viktor, Natrayan Lakshmaiya, Mohamed J. Saadh, Ayesha Amajd, Mabrouk A. Abo-Zaid, Roxana Yolanda Castillo-Acobo, Ahmed H. Ismail, Ali H. Amin, Reza Akhavan-Sigari Molecular Cancer, 2023
Synthesis and characterization of oxovanadium(IV) macrocyclic complexes with ligands derived by condensation of furil with 1,4-diaminobenzene or 3,4- diaminopyridine and their reactions with β- diketones International Journal of Chemtech Research, 2011