Biomaterials; metal nanoparticles, magnetic nanoparticles, carbohydrate polymer, drug delivery, herbal drugs, Pharmaceutical Analysis
86
Scopus Publications
2147
Scholar Citations
24
Scholar h-index
55
Scholar i10-index
Scopus Publications
Development and preclinical evaluation of quiniodochlor-loaded nanostructured lipid carrier-chitosan gel for topical antifungal therapy Ujjwal Kumar Biswas, Anindya Bose, Sweet Naskar, Mayukh Jana Discover Nano, 2026 BACKGROUND: The rising incidence of superficial fungal infections and the limitations of conventional topical therapies necessitate the development of advanced, targeted delivery systems. OBJECTIVE: This study aimed to develop and evaluate a novel quiniodochlor (QD)-loaded nanostructured lipid carrier (NLC) gel for enhanced topical antifungal therapy. METHODS: 80, and incorporated into a chitosan hydrogel. Formulations were characterized for particle size, polydispersity index (PDI), zeta potential, entrapment efficiency (EE%), drug release, and physicochemical stability. The developed gel was further evaluated for spreadability, extrudability, ex vivo skin permeation/retention, in vitro antifungal activity against Candida albicans, and in vivo skin irritation. RESULTS: The optimized NLCs exhibited nanoscale particle sizes (141.86-250.79) high EE% (> 98%), and low PDI (0.28-0.43). Despite a near-neutral zeta potential, colloidal stability was maintained, attributed to steric stabilization. The NLC gel showed a sustained drug release profile, significantly higher skin retention, and about 1.6-fold larger zone of inhibition against C. albicans compared to a marketed QD cream. Ex vivo studies confirmed enhanced dermal accumulation with negligible transdermal permeation. The formulation demonstrated excellent spreadability and extrudability, and elicited no signs of erythema or edema in an in vivo skin irritation model. CONCLUSION: The developed QD-NLC-chitosan gel presents a promising, safe, and effective topical strategy with enhanced skin targeting, sustained local release, and superior antifungal activity, demonstrating strong potential as an advanced therapeutic alternative for superficial mycoses.
Green Synthesis of Metal Nanoparticles T. I. Shabatina, A. Bose, Ya. A. Gromova, O. I. Vernaya, M. Ya. Melnikov Moscow University Chemistry Bulletin, 2026 Abstract Nanoscale materials are unique research objects which attract growing attention due to their special physical and chemical properties and a wide range of applications. There is a trend in science towards the introduction of “green technology” into production of varied materials, including metal nanoparticles, in the last decade. The development of synthetic procedures that use various plant extracts and microorganisms, rather than toxic substances, is becoming increasingly important. This review discusses the current and modern methods of green chemistry underlying the production and stabilization of gold, silver, copper, platinum, and palladium metal nanoparticles. In addition, the review describes the practical applications of metal nanoparticles, including medicine for diagnosis and therapy of various diseases.
Identification of possible Anti-Alzheimer Mechanism of ginkgo biloba extract ‘EGB761’ using molecular docking technique Pratap Kumar Sahu, Shakti Ketan Prusty, Hyking Acharjee, Anindya Bose Research Journal of Biotechnology, 2026 Ginkgo biloba exerts (EGb761) is an effective and popular herbal medicine in patients with Alzheimer's disease; however, its exact mechanism of action remains uncertain. This study aims to investigate the role of phytoconstituents of G. biloba extract in treating Alzheimer's disease. The major Alzheimer's disease related target proteins are systematically investigated for their possible molecular interaction with major active constituents of G. biloba using molecular docking techniques in silico. The results indicated that the protective effects of G. biloba extract on Alzheimer's disease may be a result of the synergistic effect of its various phytoconstituents on multiple Alzheimer's disease targets, with most of the active compounds most efficiently interacting with acetylcholinesterase and butyrylcholinesterase. The findings of this study enhance our understanding of the molecular mechanism of G. biloba extract in Alzheimer's disease and provide valuable insights for the future development of therapeutic strategies.
Garlic Extract-Mediated SPIONs-Incorporated Nanohydrogel for Enhanced Wound Healing Potential Ankita Parmanik, Anindya Bose, Lipsa Leena Panigrahi, Rudra Narayan Sahoo, Amit Kumar Nayak Current Drug Delivery, 2026 Background: Superparamagnetic iron oxide nanoparticles (SPIONs) with a specific size range of 15-70 nm are usually considered nontoxic substances with superior antibacterial activity, making them strong candidates for wound dressing applications. Although SPIONs have significant antibacterial activity, their ability to treat infected wounds still needs to be explored. Objective: The objective of the present study was to synthesize antibacterial SPIONs (G-SPIONs) using aqueous garlic extract as a bioreducing agent and evaluate the synthesized G-SPIONsincorporated nanohydrogel for wound healing potential. Methods: Synthesized G-SPIONs were characterized by SEM, zeta potential, VSM, FTIR, etc. The antibacterial effects of G-SPIONs were evaluated against S. epidermidis, S. aureus, and E. coli, as compared to garlic extract. The synthesized G-SPIONs were further incorporated into the chitosanbased hydrogel (ChiG-SPIONs) to assess their wound healing potential using the in vivo rat model. Results: The synthesized G-SPIONs had a positive surface charge of +3.82 mV and were spherical, with sizes ranging between 20-80 nm. Additionally, their hemo-biocompatible nature was confirmed by hemolysis assay. The magnetic nature of synthesized G-SPIONs was investigated using a vibrating sample magnetometer, and the saturation magnetization (Ms) was found to be 53.793emu/g. The in vivo wound healing study involving rats revealed a wound contraction rate of around 95% with improved skin regeneration. The histopathological examination demonstrated a faster rate of reepithelialization with regeneration of blood vessels and hair follicles. Conclusion: The results demonstrated that the developed ChiG-SPIONs could be a novel and efficient nanohydrogel dressing material for the effective management of wound infections.
Green-Synthesized Metal Nanoparticles Coated With Chitosan: Enhanced Stability and Antimicrobial Potential Against ESKAPE Pathogens Susrita Sharma, Anindya Bose, Prafful P. Kothari, Sri Ganga Padaga, Swati Biswas Chemistry and Biodiversity, 2026 The global challenge of multidrug resistance and the rapid spread of ESKAPE bacteria necessitate the urgent development of safe and effective antimicrobial agents. Metal nanoparticles (MNPs) offer promise due to their unique properties but are hindered by challenges, such as agglomeration, which reduces their stability and efficacy. Surface coating with chitosan is a promising solution that synergistically enhances stability and antimicrobial activity. This study explored the green synthesis of silver (Ag), gold (Au), zinc oxide (ZnO), and copper (Cu) nanoparticles using Cyperus rotundus extract, followed by surface coating with chitosan, to assess improvements in stability and antimicrobial activity against two representative ESKAPE bacteria— Pseudomonas aeruginosa and Staphylococcus aureus . The results varied, with chitosan affecting the agglomeration and stability of each metal differently. Although agglomeration significantly influenced stability, it did not strongly affect antimicrobial activity. This study highlights that preventing agglomeration is crucial for ensuring the stability of MNPs, and chitosan coating plays a critical role in preventing agglomeration and enhancing nanoparticle stability without necessarily dictating antimicrobial efficacy. Importantly, CH@AgNPs show significant potential as an alternative to antibiotics against multidrug‐resistant ESKAPE pathogens, supporting their further development for pharmaceutical applications.
Evaluation of antibacterial and antibiofilm activities of green-synthesized iron oxide nanoparticles using Cyperus rotundus extract as a reducing and stabilizing agent Ankita Parmanik, Prafful Pradeep Kothari, Anindya Bose, Swati Biswas Journal of Materials Science Materials in Medicine, 2025 The development of Iron oxide nanoparticles (IONPs) from the green sources has significant attraction due to their eco-compatibility, safety, and nontoxic nature. This work demonstrated the synthesis of IONPs using the aqueous root extract of Cyperus rotundus, a traditional antibacterial plant source (Cr-IONPs). The synthesized Cr-IONPs were characterized by various analytical instruments DLS, Zeta, XRD, SEM, VSM, etc. to evaluate its physicochemical and magnetic nature. The results confirmed the uniform shape of Cr-IONPs within a size range of 30-70 nm. Additionally, they exhibited excellent colloidal stability with a Zeta potential value of -30.50 ± 1.79 mV. The VSM analysis revealed a superparamagnetic nature with zero remanence value. The antibacterial study showed that Cr-IONPs exhibited strong antibacterial potential in a concentration-dependent manner. Both Pseudomonas aeruginosa (P. aeruginosa) and Staphyllococcus aureus (S. aureus) strains demonstrated that Cr-IONPs exhibit potent antibacterial activity in a concentration-dependent manner. Furthermore, the diameter of the zone of inhibition increased with higher concentrations of the Cr-IONPs. These results demonstrate that the Cr-IONPs synthesized via a greener approach using C. rotundus extract exhibit strong antibacterial activity and biocompatibility, making them a promising candidate as a future antibacterial agent against multi-drug-resistant bacteria. Additionally, their superparamagnetic nature also broadens their potential for biomedical applications, including targeted drug delivery and diagnostics.
Green Synthesis of Metal Oxide Nanoparticles T. I. Shabatina, A. Bose, O. I. Vernaya, Y. A. Gromova, M. Ya. Melnikov Moscow University Chemistry Bulletin, 2025 Abstract Rapid advancement of nanotechnology and the increasing demand for nanomaterials (including those of metal oxide nanoparticles (NPs)) require the development of cost-effective and environmentally friendly synthesis methods. Green chemistry and its synthesis methods are an effective solution to this challenge. They enable the production of metal oxide NPs of various compositions, structures, and sizes with minimal environmental impact. Diverse green synthesis methods and reagents allow for the selection of the most cost-effective options for various regions. Modern green chemistry methods to produce and stabilize metal oxide NPs of copper, zinc, zirconium, iron, and titanium are considered in this review. Their advantages, disadvantages, and potential future developments are discussed. The properties and practical applications of metal oxide NPs obtained with green chemistry methods are also described.
Protein and peptide drug delivery system Rudra Narayan Sahoo, Kumari Priyanka, Anindya Bose Novel Formulations and Future Trends Recent and Future Trends in Pharmaceutics Volume 3, 2024
Gellan gum–based wound dressings Azim Ansari, Mohd Sayeed Shaikh, Mohd Usman Mohd Siddique, Mahendra Khairnar, Syed Sarfaraz Ali, Sameer N. Goyal, Md Saquib Hasnain, Anindya Bose, Amit Kumar Nayak Application of Gellan Gum as A Biomedical Polymer, 2024
In Vivo and In Vitro Toxicity Study of Metallic Nanoparticles Biswakanth Kar, Anindya Bose, Sudipta Roy, Pranabesh Chakraborty, Soumalya Chakraborty, Sanjoy Kumar Das, Gautam Pal, Farheen Waziri, Md Sabir Alam Metallic Nanoparticles for Health and the Environment, 2023
Acute and sub-acute toxicity study of amrtadi churna Sangeeta Mukhi, Anindya Bose, Dilip Kumar Das, Sitansu Kumar Panda, Debahuti Mohapatra, S. Latha, Ashok Kumar Balaraman Research Journal of Pharmacy and Technology, 2021
Comparative evaluation of the antioxidant activity of some commonly used spices International Journal of Pharmtech Research, 2016
Establishment of quality control parameters of panchasakara churna-a classical ayurvedic formulation International Journal of Pharmacy and Pharmaceutical Sciences, 2016
Evaluation of hepatoprotective activity of the aerial parts of Phyllanthus Reticulates against paracetamol induced hepatic damage in rats Asian Journal of Pharmaceutical and Clinical Research, 2015
Estimation of lead and arsenic in marketed Chyawanprash products International Journal of Pharmtech Research, 2014
Uterotonic properties of nymphaea alba on isolated myometrium model International Journal of Pharmacy and Pharmaceutical Sciences, 2014
Phytochemical and acute toxicity study on Tinospora tomentosa Miers Acta Poloniae Pharmaceutica Drug Research, 2009
In-vitro free radical scavenging activity of ethanolic extract of leaves of Cajanus cajan (L.) Millsp Journal of Natural Remedies, 2009
Phytochemical and acute toxicity study on Bryophyllum calycinum Salisb Acta Poloniae Pharmaceutica Drug Research, 2008
Antidiabetic and In Vivo antioxidant activity of ethanolic extract of Bacopa monnieri Linn. Aerial parts: A possible mechanism of action Iranian Journal of Pharmaceutical Research, 2008
Hepatoprotective activity of ethanolic extract of Bacopa monnieri Linn. aerial parts against CCl4-induced hepatotoxicity in rats Natural Product Sciences, 2007
In Vitro antioxidant and hepatoprotective activity of ethanolic extract of Bacopa monnieri Linn. Aerial parts Iranian Journal of Pharmacology and Therapeutics, 2007
A study on antimicrobial activity of Cleome rutidosperma DC Journal of Natural Remedies, 2007
Anthelmintic activity of various fractions of ethanolic extract of Bacopa monnieri Indian Drugs, 2006
A study of antimicrobial activity of Bacopa monnieri Linn. aerial parts Journal of Natural Remedies, 2006
Analgesic and locomotor activity of extracts of Cleome rutidosperma DC Indian Journal of Pharmaceutical Sciences, 2004
RECENT SCHOLAR PUBLICATIONS
Comparative Analysis of Chitosan from Diverse Indian Fishery Wastes: Characterization and in Vitro Physicochemical and Biological Assessment for Pharmaceutical Uses UK Biswas, A Bose, S Naskar, S Sen, S Pal Journal of Pharmaceutical Innovation 21 (2), 195 , 2026 2026
Modulating Magnetic Properties of Iron Oxide Nanoparticles via Hydrophilic Polymer Surface Functionalization A Parmanik, A Bose, RN Sahoo, JA Fedotova, AA Kharchanka, S Ota, ... Journal of Inorganic and Organometallic Polymers and Materials, 1-11 , 2026 2026
Green Synthesis of Metal Nanoparticles TI Shabatina, A Bose, YA Gromova, OI Vernaya, MY Melnikov Moscow University Chemistry Bulletin 81 (1), 1-25 , 2026 2026
Design and evaluation of Luliconazole-loaded NLC gel for enhanced dermatophytosis therapy UK Biswas, A Bose, S Naskar, S Sen Journal of Pharmaceutical Innovation 21 (1), 17 , 2026 2026 Citations: 4
Identification of possible Anti-Alzheimer Mechanism of ginkgo biloba extract ‘EGB761’ using molecular docking technique AB Pratap Kumar Sahu, Shakti Ketan Prusty, Hyking Acharjee Research Journal of Biotechnology 21 (1), 163-171 , 2026 2026
Green‐Synthesized Metal Nanoparticles Coated With Chitosan: Enhanced Stability and Antimicrobial Potential Against ESKAPE Pathogens S Sharma, A Bose, PP Kothari, SG Padaga, S Biswas Chemistry & Biodiversity 23 (1), e01885 , 2026 2026 Citations: 1
Green Synthesis of Metal Oxide Nanoparticles TI Shabatina, A Bose, OI Vernaya, YA Gromova, MY Melnikov Moscow University Chemistry Bulletin 80 (6), 349-365 , 2025 2025 Citations: 1
Silver Nanoparticles: Green Synthesis Using Medicinal Plant Extracts and Antibacterial Activity AS Ryzhkova, AA Makeeva, OI Vernaya, AV Shabatin, AM Semenov, ... Moscow University Chemistry Bulletin 80 (6), 366-374 , 2025 2025 Citations: 1
Evaluation of antibacterial and antibiofilm activities of green-synthesized iron oxide nanoparticles using Cyperus rotundus extract as a reducing and stabilizing agent A Parmanik, PP Kothari, A Bose, S Biswas Journal of Materials Science: Materials in Medicine 36 (1), 60 , 2025 2025 Citations: 7
Influence of Different Levels of Acetylation on Retrograded Corn Starch Polymer in Colon‐Targeted Budesonide Tablets A Gangopadhyay, A Bose, RN Sahoo, S Mallick Starch‐Stärke 77 (7), e70041 , 2025 2025 Citations: 3
Cyperus rotundus mediated green synthesis of silver nanoparticles for antibacterial wound dressing applications S Sharma, A Bose, S Biswas, S Sen, I Roy Scientific Reports 15 (1), 18394 , 2025 2025 Citations: 24
An insight into chemically modified chitosan and their biological, pharmaceutical, and medical applications: A review UK Biswas, A Bose, B Ghosh, S Sharma International Journal of Biological Macromolecules 303, 140612 , 2025 2025 Citations: 43
Carbon dots: A review of innovations, applications, challenges, and future prospects S Sen, A Bose Inorganic Chemistry Communications 173, 113852 , 2025 2025 Citations: 46
Detection and Estimation of Gingerol and its derivatives in Zingiber officinale Rhizome collected from different regions of Eastern India S Satapathy, A Ray, D Kar, A Bose, A Kuanar Research Journal of Pharmacy and Technology 18 (4), 1702-1708 , 2025 2025 Citations: 1
Magnetic nanoparticles used in biosensors A Parmanik, A Bose Materials and Components of Biosensors in Healthcare, 165-174 , 2025 2025 Citations: 4
Garlic Extract-Mediated SPIONs-Incorporated Nanohydrogel for Enhanced Wound Healing Potential A Parmanik, A Bose, LL Panigrahi, RN Sahoo, AK Nayak Current drug delivery , 2025 2025 Citations: 3
Applications of biosensors for wound healing management B Ghosh, A Bose Applications of Biosensors in Healthcare, 417-438 , 2025 2025 Citations: 1
Nanostructured lipid carrier-based topical gels as novel drug delivery system: a comprehensive overview UK Biswas, S Sen, S Sharma, M Paul, AK Nayak, A Bose Current Drug Delivery , 2024 2024 Citations: 4
Recent advances in the preparation, properties, and applications of solid lipid nanoparticles in drug delivery UK Biswas, A Bose, A Parmanik Pharmaceutical Nanotechnology , 2024 2024 Citations: 4
Mentha spicata Mediated Formulation of Iron Oxide Nanoparticles Exhibit Superior Antimicrobial, Antioxidant, and Photodegradation Propensity Compared to Chemically Formulated … LL Panigrahi, S Shekhar, A Sarangi, S Satpathy, A Parmanik, A Bose, ... Current topics in medicinal chemistry , 2024 2024
MOST CITED SCHOLAR PUBLICATIONS
Current treatment strategies against multidrug-resistant bacteria: a review A Parmanik, S Das, B Kar, A Bose, GR Dwivedi, MM Pandey Current microbiology 79 (12), 388 , 2022 2022 Citations: 339
Anthelmintic activity of Bacopa monnieri . T Ghosh, TK Maity, A Bose, GK Dash 2005 Citations: 128
Analgesic, anti-inflammatory and antipyretic activities of the ethanolic extract and its fractions of Cleome rutidosperma A Bose, S Mondal, JK Gupta, T Ghosh, GK Dash, S Si Fitoterapia 78 (7-8), 515-520 , 2007 2007 Citations: 119
Antidiabetic and in vivo antioxidant activity of ethanolic extract of Bacopa monnieri Linn. aerial parts: a possible mechanism of action T Ghosh, MT KUMAR, P Sengupta, DK Dash, A Bose IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH (IJPR) 7 (1), 61-68 , 2008 2008 Citations: 111
In vitro antioxidant and hepatoprotective activity of ethanolic extract of Bacopa monnieri Linn. aerial parts T Ghosh, TK Maity, M Das, A Bose, DK Dash IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT) 6 (1), 77-85 , 2007 2007 Citations: 72
Hepatoprotective activity of Tagetes erecta against carbon tetrachloride-induced hepatic damage in rats RK Giri, A Bose, SK Mishra Acta Poloniae Pharmaceutica n Drug Research 68 (6), 999-1003 , 2011 2011 Citations: 48
Pharmacognostic, physicochemical and chromatographic characterization of Samasharkara Churna S Mukhi, A Bose, P Panda, MM Rao Journal of Ayurveda and integrative medicine 7 (2), 88-99 , 2016 2016 Citations: 47
Studies on diuretic and laxative activity of ethanolic extract and its fractions of Cleome rutidosperma aerial parts. A Bose, S Mondal, JK Gupta, GK Dash, T Ghosh, S Si 2006 Citations: 47
Carbon dots: A review of innovations, applications, challenges, and future prospects S Sen, A Bose Inorganic Chemistry Communications 173, 113852 , 2025 2025 Citations: 46
Phytochemical and acute toxicity study on Bryophyllum calycinum Salisb P Devbhuti Acta poloniae pharmaceutica , 2008 2008 Citations: 46
An insight into chemically modified chitosan and their biological, pharmaceutical, and medical applications: A review UK Biswas, A Bose, B Ghosh, S Sharma International Journal of Biological Macromolecules 303, 140612 , 2025 2025 Citations: 43
Evaluation of anthelmintic activity of Pistia stratiotes Linn HKS Kumar, A Bose, A Raut, SK Sahu, MBV Raju Journal of Basic and Clinical Pharmacy 1 (2), 103 , 2010 2010 Citations: 41
Physicochemical characterization and in vitro dissolution performance of ibuprofen-Captisol®(sulfobutylether sodium salt of β-CD) inclusion complexes SK Das, N Kahali, A Bose, J Khanam Journal of molecular liquids 261, 239-249 , 2018 2018 Citations: 40
Diuretic and antibacterial activity of aqueous extract of Cleome rutidosperma DC A Bose, J Gupta, G Dash, T Ghosh, S Si, D Panda Indian Journal of Pharmaceutical Sciences 69 (2), NA-NA , 2007 2007 Citations: 39
Development and characterization of natural product derived macromolecules based interpenetrating polymer network for therapeutic drug targeting A Biswas, S Mondal, SK Das, A Bose, S Thomas, K Ghosal, S Roy, ... ACS omega 6 (43), 28699-28709 , 2021 2021 Citations: 36
Comparative evaluation of the antioxidant activity of some commonly used spices M Mallick, A Bose, S Mukhi International Journal of PharmTech Research 9 (1), 1-8 , 2016 2016 Citations: 35
Synthesis and evaluation of 1, 3 Di-substituted schiff, mannich bases and spiro isatin derivatives P Mondal, S Jana, A Bose, M Banerjee Journal of Young Pharmacists 2 (2), 169-172 , 2010 2010 Citations: 34
Analysis of steady state and non-steady state corneal permeation of diclofenac R Mohapatra, S Mallick, A Nanda, RN Sahoo, A Pramanik, A Bose, D Das, ... RSC advances 6 (38), 31976-31987 , 2016 2016 Citations: 33
Ayurvedic Balarista ameliorate anti-arthritic activity in adjuvant induced arthritic rats by inhibiting pro-inflammatory cytokines and oxidative stress C Das, A Bose, D Das Journal of traditional and complementary medicine 11 (3), 228-237 , 2021 2021 Citations: 32
Bioactivities of Allicin and related organosulfur compounds from garlic: Overview of the literature since 2010 SK Mandal, A Das, S Dey, U Sahoo, S Bose, A Bose, N Dhiman, S Madan, ... Egyptian Journal of Chemistry 62 (Special Issue (Part 1) Innovation in … , 2019 2019 Citations: 31
