Design of La@ZnO/AuNPs/GO nanocomposites as an electrochemical sensor for acetaminophen detection Hamna Shafaq, Saima Anjum, Sidra Tul Muntaha, Nawal Qureshi, Muhammad Imran Khan, Abdallah Shanableh, Sameh M. Osman, Rafael Luque Sensing and Bio Sensing Research, 2025 This study was aimed to design an innovative and highly sensitive electrochemical sensor for Acetaminophen analysis. La@ZnO/AuNPs/GO nanocomposite was synthesized via hydrothermal approach for the detection of acetaminophen in pharmaceutical products and biological samples. Characterization of La@ZnO/AuNPs/GO was conducted using UV–visible spectroscopy, Fourier transform infrared, X-ray powder diffraction, EIS and electrochemical determination was carried out by DPV and CV. Voltammetric results showed an increased oxidation peak current due to fast electron transfer, which confirmed the oxidation of acetaminophen. DPV was performed for different concentrations of acetaminophen in the range of 0.5–1750 μM. LOD and LOQ for La@ZnO/AuNPs/GO were 0.45 μM and 1.50 μM respectively, for AP detection. The sensor demonstrated a remarkably wide linear detection range, a low detection limit, sustained stability over 25 days, minimal interference, rapid determination capabilities, excellent reproducibility, and consistent repeatability for precise Acetaminophen quantification. These findings indicate that La@ZnO/AuNPs/GO is an exceptional electrode material for identifying the electrocatalytic activity of low-level Acetaminophen. • La@ZnO/AuNPs/GO for enhanced electrochemical detection of Acetaminophen (AP). • Voltammetric studies reveal increased oxidation peak current (rapid electron transfer and efficient AP oxidation). • Low limit of detection (LOD) of 18.57 μM and quantification (LOQ) of 56.26 μM for AP. • Wide linear detection range (0.5–1750 μM). • La@ZnO/AuNPs/GO demonstrates stability, minimum interference, rapid determination, and high reproducibility.
Iridium(Ir) decorated silicon Carbide (SiC) nanosheet as a promising sensitive material for detection of γ-Hydroxybutyric acid drug based on the DFT approach Mohamed J. Saadh, Yathrib Ajaj, Mohammed Ahmed Mustafa, Nada Othman Kattab, Sameh M. Osman, Hijaz Ahmad, Salim B. Alsaadi, Ahmed Read Al-Tameemi, Ahmed Elawady Molecular Physics, 2025 The Food and Drug Administration (FDA) has banned gamma-Hydroxybutyric acid (HBA), which is widely utilised for drug-facilitated sexual assaults across the world. As a result, it is crucial for law enforcement and drug organisations to detect HBA in biological settings. There has been substantial interest in 2D chemical nanosensors for gaseous and biological molecule detection. This paper studied the sensing performance of bare and Ir-decorated SiC nanosheets for HBA detection through the TPSS density functional. The bare SiC nanosheets were found to have insignificant responsiveness to HBA (almost 7.3 at 298 K) due to their small binding energy with the drug molecules (−0.26 eV). The Ir-decorated SiC nanosheets, however, showed superb performance in adsorbing HBA on an Si–C bond, with a binding energy of −2.54 eV. The Ir-decorated SiC nanosheets enabled strong HBA adsorption (binding energy = −1.35 eV). Therefore, the decoration of SiC sheets with Ir atoms remarkably enhanced their responsiveness to HBA molecules from 7.3 to 495.4. The recovery time for the desorption of HBA molecules from the surface of the Ir-decorated SiC nanosheets was estimated to be 1.09 s. It was concluded that Ir-decorated SiC nanosheets are a promising nanosensor to detect HBA.
Electrochemical polymerized DL-phenylalanine modified carbon nanotube sensor for the selective and sensitive determination of caffeic acid with riboflavin Kanthappa B, J. G. Manjunatha, Sameh Mohamed Osman, Narges Ataollahi Scientific Reports, 2024 In this study, DL-phenylalanine modified with a multiwall carbon nanotube paste electrode is used as advanced electrochemical sensor for analysing of 0.1 mM caffeic acid (CFA) with simultaneous detection of riboflavin (RFN). The developed sensors include electrochemically polymerized DL-phenylalanine (DL-PA) modified multiwall carbon nanotube paste electrode [DL-PAMMCNTPE] and bare multiwall carbon nanotube paste electrode [BMCNTPE]. The increasing stability in the developed electrochemical sensor for the quantification of CFA is highlighted in detail, along with its characterization using voltammetric techniques such as electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), differential pulse voltammetry (DPV), and linear Sweep Voltammetry (LSV). Scanning electron microscopy (SEM) technique was used to studied the structural analysis of BMCNTPE and DL-PAMMCNTPE surface. The investigation of 0.1 mM CFA in 0.2 M phosphate buffered solution (PBS) using a 7.0 pH at 0.1 V/s scan rate was highlighted using DL-PAMMCNTPE, which shows good electrochemical responses compared to BMCNTPE. This work characterizes the voltammetric responses by inspecting the pH effect, scan rate effect, and concentration difference of CFA at the DL-PAMMCNTPE surface. The CFA responses specify that the scan rate progress is adsorption controlled. The concentration of CFA detection was started from 20 μM to 600 μM using DPV method, with lower limit of detection (LOD) of 0.280 μM and limit of quantification (LOQ) of 0.936 μM. And for CV method concentration range 20 to 550 μM, with LOD of 0.198 μM and LOQ of 0.702 μM. Furthermore, the developed electrochemical sensor responses are shows good stability, repeatability, and reproducibility, for CFA. The analytical applicability of CFA in apple juice and coffee powder samples was also evaluated.
Harvesting Energy Via Water Movement and Surface Ionics in Microfibrous Ceramic Wools Manpreet Kaur, Avinash Alagumalai, Omid Mahian, Sameh M. Osman, Tadaaki Nagao, Zhonglin Wang Energy and Environmental Materials, 2024 Due to the push for carbon neutrality in various human activities, the development of methods for producing electricity without relying on chemical reaction processes or heat sources has become highly significant. Also, the challenge lies in achieving microwatt‐scale outputs due to the inherent conductivity of the materials and diverting electric currents. To address this challenge, our research has concentrated on utilizing nonconductive mediums for water‐based low‐cost microfibrous ceramic wools in conjunction with a NaCl aqueous solution for power generation. The main source of electricity originates from the directed movement of water molecules and surface ions through densely packed microfibrous ceramic wools due to the effect of dynamic electric double layer. This occurrence bears resemblance to the natural water transpiration in plants, thereby presenting a fresh and straightforward approach for producing electricity in an ecofriendly manner. The generator module demonstrated in this study, measuring 12 × 6 cm2, exhibited a noteworthy open‐circuit voltage of 0.35 V, coupled with a short‐circuit current of 0.51 mA. Such low‐cost ceramic wools are suitable for ubiquitous, permanent energy sources and hold potential for use as self‐powered sensors and systems, eliminating the requirement for external energy sources such as sunlight or heat.
Design of Manganese-Doped Zinc Oxide Nanoparticles as Effective Electrocatalytic System in Oxygen Reduction Reactions Shaista Noor, Fawad Ahmad, Muhammad Imran Khan, Abdallah Shanableh, Shakir Khan, Suryyia Manzoor, Sameh M. Osman, Rafael Luque Applied Organometallic Chemistry, 2024 Fuel cell technologies constitute a clean, reliable, highly efficient, and eco‐friendly source of alternative energy generation. However, they still require a reliable and robust catalytic system showing comparative electrochemical activity to precious metal Pt with less cost. In this work, Mn@ZnO NPs were synthesized using a hydrothermal‐assisted simple method. Several techniques including SEM, TGA, and XRD were used to confirm the material synthesis. Electrochemical properties were analyzed by using linear sweep voltammetry, chronoamperometry, and cyclic voltammetry. A higher ORR activity in terms of mass activity and current density was observed 133.9 mA/mg as compared to Pt/C (96 mA/mg) and Pd/C (67 mA/mg) under otherwise identical conditions. Mn@ZnO also exhibited excellent current density (1.913 mA cm−2), comparable to Pt/C (1.55 mA cm−2). Chronoamperometry shows stability for up to 800 s. Comparative studies were conducted in both acidic and basic mediums, with observed higher ORR activity in acidic media.
Synthesis of biochar modified with 12-tungstophosphoric acid for the selective conversion of isoeugenol to vanillin Ana Alice Farias da Costa, Alex de Nazaré de Oliveira, Rutiléia de Jesus Paiva, Luiza Helena de Oliveira Pires, Eloísa Helena de Aguiar Andrade, Patrícia Teresa Souza da Luz, Renata Coelho Rodrigues Noronha, Geraldo Narciso da Rocha Filho, Carlos Emmerson Ferreira da Costa, Sameh M. Osman, Rafael Luque, Luís Adriano Santos do Nascimento Arabian Journal of Chemistry, 2023
Esterification of an Agro-Industrial Waste on Kaolinite-Derived Catalyst Prepared via Microwave Irradiation Alex de Nazaré de Oliveira, Irlon Maciel Ferreira, David Esteban Quintero Jimenez, Linéia Soares da Silva, Ana Alice Farias da Costa, Luíza Helena de Oliveira Pires, Rafael Luque, Sameh M. Osman, Carlos Emmerson Ferreira da Costa, Geraldo Narciso da Rocha Filho, Luís Adriano Santos do Nascimento Waste and Biomass Valorization, 2022
Benzothiazole derivatives as anticancer agents Ali Irfan, Fozia Batool, Syeda Andleeb Zahra Naqvi, Amjad Islam, Sameh M. Osman, Alessio Nocentini, Siham A. Alissa, Claudiu T. Supuran Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Design of La@ ZnO/AuNPs/GO nanocomposites as an electrochemical sensor for acetaminophen detection H Shafaq, S Anjum, ST Muntaha, N Qureshi, MI Khan, A Shanableh, ... Sensing and Bio-Sensing Research, 100929 , 2025 2025 Citations: 4
Development of piperidinium-grafted anion exchange membranes for desalination applications via electrodialysis process MI Khan, A Shanableh, MH Lashari, S Manzoor, SM Osman, R Luque Results in Engineering, 107832 , 2025 2025 Citations: 1
Enhanced supercapacitor performance of rGO-Supported BaVO3 nanostructures as advanced electrode materials A Sami, MM Khan, Z Haidar, AAA Bahajjaj, S Riaz, S Naseem, SM Osman, ... Ceramics International 51 (7), 8480-8491 , 2025 2025 Citations: 19
Iridium (Ir) decorated silicon Carbide (SiC) nanosheet as a promising sensitive material for detection of γ-Hydroxybutyric acid drug based on the DFT approach MJ Saadh, Y Ajaj, MA Mustafa, NO Kattab, SM Osman, H Ahmad, ... Molecular Physics 123 (2), e2356754 , 2025 2025
Electrochemical polymerized DL-phenylalanine modified carbon nanotube sensor for the selective and sensitive determination of caffeic acid with riboflavin JG Manjunatha, SM Osman, N Ataollahi Scientific Reports 14 (1), 30950 , 2024 2024 Citations: 8
Improving syngas yield and quality from biomass/coal co-gasification using cooperative game theory and local interpretable model-agnostic explanations C Efremov, TT Le, P Paramasivam, K Rudzki, SM Osman, TH Chau International Journal of Hydrogen Energy 96, 892-907 , 2024 2024 Citations: 26
Excellent catalytic performance over reduced graphene-boosted novel nanoparticles for oxidative desulfurization of fuel oil T Irshad, M Saeed, M Munir, R Kousar, A Intisar, MI Din, H Ahsan, ... Nanotechnology Reviews 13 (1), 20240116 , 2024 2024 Citations: 6
Forecasting energy consumption and carbon dioxide emission of Vietnam by prognostic models based on explainable machine learning and time series TT Le, P Sharma, SM Osman, M Dzida, PQP Nguyen, MH Tran, DN Cao, ... Clean Technologies and Environmental Policy 26 (12), 4405-4431 , 2024 2024 Citations: 20
Deep‐eutectic‐solvent‐assisted hydrothermal carbonization of sewage sludge for green wood bioadhesive production ZX Xu, R Dou, Y Tan, HR Xiong, YX Chen, LJ Leng, M Vlaskin, ... Biofuels, Bioproducts and Biorefining 18 (6), 1978-1993 , 2024 2024 Citations: 7
Techno-economic analysis of a hybrid energy system for electrification using an off-grid solar/biogas/battery system employing HOMER: A case study in Vietnam P Sharma, BJ Bora, TMT Bui, C Efremov, MH Tran, J Kowalski, SM Osman, ... Process Safety and Environmental Protection 191, 1353-1367 , 2024 2024 Citations: 48
Co-gasification of waste biomass-low grade coal mix using downdraft gasifier coupled with dual-fuel engine system: Multi-objective optimization with hybrid approach using RSM … TT Le, P Sharma, BJ Bora, J Kowalski, SM Osman, DTN Le, TH Truong, ... Process Safety and Environmental Protection 191, 234-248 , 2024 2024 Citations: 10
Design of Manganese‐Doped Zinc Oxide Nanoparticles as Effective Electrocatalytic System in Oxygen Reduction Reactions S Noor, F Ahmad, MI Khan, A Shanableh, S Khan, S Manzoor, SM Osman, ... Applied Organometallic Chemistry 38 (11), e7676 , 2024 2024 Citations: 15
Development of comprehensive models for precise prognostics of ship fuel consumption TT Le, P Sharma, NDK Pham, DTN Le, VV Le, SM Osman, L Rowinski, ... Journal of Marine Engineering & Technology 23 (6), 451-465 , 2024 2024 Citations: 19
Design of activated bentonite-based catalysts for the esterification of residual free fatty acids from palm oil PTS da Luz, BF de Moraes, RK Ferreira, CC de Melo, AN de Oliveira, ... Catalysis Today 441, 114886 , 2024 2024 Citations: 6
Harvesting Energy Via Water Movement and Surface Ionics in Microfibrous Ceramic Wools M Kaur, A Alagumalai, O Mahian, SM Osman, T Nagao, Z Wang Energy & Environmental Materials 7 (6), e12760 , 2024 2024 Citations: 2
Green wood bio-adhesives from cellulose-derived bamboo powder hydrochars YX Chen, HS Zhu, F Gao, HR Xiong, H Yang, ZX Xu, PG Duan, LJ Zheng, ... Chemical Engineering Journal 498, 155667 , 2024 2024 Citations: 22
Iron oxide decorated hexagonal boron nitride modified electrochemical sensor for the detection of nitrofurantoin in human urine samples G Sridharan, CJT Godwin, R Atchudan, S Arya, M Govindasamy, ... Journal of the Taiwan Institute of Chemical Engineers 163, 105320 , 2024 2024 Citations: 64
Improving the prediction of biochar production from various biomass sources through the implementation of eXplainable machine learning approaches VG Nguyen, P Sharma, Ü Ağbulut, HS Le, DN Cao, M Dzida, SM Osman, ... International Journal of Green Energy 21 (12), 2771-2798 , 2024 2024 Citations: 32
An environmentally greener and reusability approach for bioenergy production using Mallotus philippensis (Kamala) seed oil feedstock via phytonanotechnology B Chaudhry, S Sultana, Z Zhang, M Ahmad, M Munir, SM Osman, ... Nanotechnology Reviews 13 (1), 20240025 , 2024 2024 Citations: 4
Deep learning-enabled integration of renewable energy sources through photovoltaics in buildings M Arun, TT Le, D Barik, P Sharma, SM Osman, VK Huynh, J Kowalski, ... Case Studies in Thermal Engineering 61, 105115 , 2024 2024 Citations: 58
MOST CITED SCHOLAR PUBLICATIONS
Benzothiazole derivatives as anticancer agents A Irfan, F Batool, SA Zahra Naqvi, A Islam, SM Osman, A Nocentini, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 265-279 , 2020 2020 Citations: 318
Nickel hydroxide‐supported Ru single atoms and Pd nanoclusters for enhanced electrocatalytic hydrogen evolution and ethanol oxidation A Pei, G Li, L Zhu, Z Huang, J Ye, YC Chang, SM Osman, CW Pao, Q Gao, ... Advanced Functional Materials 32 (51), 2208587 , 2022 2022 Citations: 206
Review on biofuel production: Sustainable development scenario, environment, and climate change perspectives− A sustainable approach S Prasad, KK Yadav, S Kumar, P Pandita, JK Bhutto, MA Alreshidi, ... Journal of Environmental Chemical Engineering 12 (2), 111996 , 2024 2024 Citations: 139
Novel 1, 3, 5-triazine-based pyrazole derivatives as potential antitumor agents and EFGR kinase inhibitors: Synthesis, cytotoxicity, DNA binding, molecular docking and DFT studies MS Raghu, CBP Kumar, MK Prashanth, KY Kumar, BS Prathibha, ... New Journal of Chemistry 45 (31), 13909-13924 , 2021 2021 Citations: 125
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases M Durgun, C Türkeş, M Işık, Y Demir, A Saklı, A Kuru, A Güzel, ... Journal of enzyme inhibition and medicinal chemistry 35 (1), 950-962 , 2020 2020 Citations: 112
A Review on the Effect of Various Chemical Treatments on the Mechanical Properties of Renewable Fiber‐Reinforced Composites M Aravindh, S Sathish, R Ranga Raj, A Karthick, V Mohanavel, PP Patil, ... Advances in Materials Science and Engineering 2022 (1), 2009691 , 2022 2022 Citations: 105
Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs F Carta, D Vullo, SM Osman, Z AlOthman, CT Supuran Bioorganic & medicinal chemistry 25 (9), 2569-2576 , 2017 2017 Citations: 103
Pt nanoparticle–Mn single-atom pairs for enhanced oxygen reduction X Wei, S Song, W Cai, Y Kang, Q Fang, L Ling, Y Zhao, Z Wu, X Song, ... ACS nano 18 (5), 4308-4319 , 2024 2024 Citations: 93
Salt-assisted construction of hydrophilic carbon nitride photocatalysts with abundant water molecular adsorption sites for efficient hydrogen production C Wang, Y Lu, Z Wang, H Liao, W Zhou, Y He, SM Osman, M An, ... Applied Catalysis B: Environment and Energy 350, 123902 , 2024 2024 Citations: 90
Integrating Nanomaterial and High‐Performance Fuzzy‐Based Machine Learning Approach for Green Energy Conversion A Sujith, R Swathi, R Venkatasubramanian, N Venu, S Hemalatha, ... Journal of Nanomaterials 2022 (1), 5793978 , 2022 2022 Citations: 86
Effects on the Physicochemical Properties of Hydrochar Originating from Deep Eutectic Solvent (Urea and ZnCl 2 )-Assisted Hydrothermal Carbonization of Sewage … Z Xu, X Ma, J Liao, SM Osman, S Wu, R Luque ACS Sustainable Chemistry & Engineering 10 (13), 4258-4268 , 2022 2022 Citations: 83
Silica-derived materials from agro-industrial waste biomass: Characterization and comparative studies CA Morales-Paredes, I Rodríguez-Linzán, MD Saquete, R Luque, ... Environmental Research 231, 116002 , 2023 2023 Citations: 77
Biochemical characterization of recombinant β-carbonic anhydrase (PgiCAb) identified in the genome of the oral pathogenic bacterium Porphyromonas gingivalis S Del Prete, D Vullo, V De Luca, Z AlOthman, SM Osman, CT Supuran, ... Journal of Enzyme Inhibition and Medicinal Chemistry 30 (3), 366-370 , 2015 2015 Citations: 77
Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D … A Petreni, A Bonardi, C Lomelino, SM Osman, ZA ALOthman, ... European journal of medicinal chemistry 190, 112112 , 2020 2020 Citations: 71
Comparison of the sulfonamide inhibition profiles of the α-, β-and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae S Del Prete, D Vullo, V De Luca, V Carginale, SM Osman, Z AlOthman, ... Bioorganic & Medicinal Chemistry Letters 26 (8), 1941-1946 , 2016 2016 Citations: 71
Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae S Del Prete, D Vullo, V De Luca, V Carginale, M Ferraroni, SM Osman, ... Bioorganic & medicinal chemistry 24 (5), 1115-1120 , 2016 2016 Citations: 70
Bimetallic metal-organic framework-derived porous one-dimensional carbon materials for electrochemical sensing of dopamine S Chowdhury, AS Nugraha, R O'May, X Wang, P Cheng, R Xin, ... Chemical Engineering Journal 492, 152124 , 2024 2024 Citations: 69
Iron oxide decorated hexagonal boron nitride modified electrochemical sensor for the detection of nitrofurantoin in human urine samples G Sridharan, CJT Godwin, R Atchudan, S Arya, M Govindasamy, ... Journal of the Taiwan Institute of Chemical Engineers 163, 105320 , 2024 2024 Citations: 64
Anion inhibition profiles of α-, β-and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae S Del Prete, D Vullo, V De Luca, V Carginale, P di Fonzo, SM Osman, ... Bioorganic & Medicinal Chemistry 24 (16), 3413-3417 , 2016 2016 Citations: 60
Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii D Vullo, S Del Prete, SM Osman, V De Luca, A Scozzafava, Z AlOthman, ... Bioorganic & Medicinal Chemistry Letters 24 (1), 275-279 , 2014 2014 Citations: 60
