The Milan Score is an Effective Manometric Tool to Predict Gastroesophageal Reflux in Patients With Laryngopharyngeal Symptoms Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Ivan Kristo, Nicola De Bortoli, Salvatore Tolone, Elisa Marabotto, Daniele Bernardi, Sebastian F. Schoppmann, Roberto Penagini, Benjamin Rogers, Anthony Hobson, Jordan Haworth, Brian Louie, Yeong Yeh Lee, Vincent Tee, Takahiro Masuda, Dimitrios Theodorou, Tania Triantafyllou, Benedetta Barcella, Lorenzo Cusmai, Michele Puricelli, Marina Coletta, Vito Annese, Edoardo Vincenzo Savarino, Emanuele Luigi Giuseppe Asti, C. Prakash Gyawali Neurogastroenterology and Motility, 2026 IntroductionAccording to Lyon 2.0, laryngopharyngeal symptoms (LPS) should undergo upfront pathophysiologic tests. The novel Milan score integrates esophagogastric junction (EGJ) morphology, ineffective esophageal motility, EGJ‐contractile integral (EGJ‐CI), and straight leg raise (SLR) response. It has been demonstrated to predict abnormal AET. The aim of this study was to assess the value of the Milan score in predicting GERD in these patients.MethodsWe prospectively enrolled patients with suspected GERD who underwent HRM and MII pH from 12 referral centers. Patients with isolated LPS (reflux symptom index > 13) were compared with typical GERD symptoms (GERD‐HRQL ≥ 10). A Milan score > 137 was considered positive. The effectiveness of the Milan score in the identification of patients with pathologic GERD was assessed.ResultsOf 570 patients (49% females, median age 49 years, BMI 24 kg/m2), isolated LPS was found in 30 patients and isolated typical symptoms in 154. An AET > 6% was found in 23% of the LPS group and 43% of the typical symptom group (p = 0.034). The Milan score was higher in the typical symptoms group, with higher scores for EGJ‐CI (p = 0.039) and SLR response (p = 0.038) components. The likelihood of concordance of the Milan score and AET on reflux monitoring was similar (83.3% vs. 84.4%, p = 0.532).ConclusionsPatients with isolated LPS demonstrated a lower likelihood of EGJ disruption, pathologic GERD, and abnormal Milan score. The Milan score performed similarly well in the identification of GERD in both LPS and typical symptoms and could therefore be used as an upfront test in LPS patients.
Effects of Traditional Asian Diet on dietary fibre requirement, gut microbiome composition, and faecal and urine metabolomes in healthy Asian women: a pilot study N.-F. Sahran, C.W. Chong, I.H. Ismail, F. Taib, P.S. Hoo, U.D. Palanisamy, U. Sundralingam, C.S.J. Teh, Z.X. Kong, Q. Ayub, F. Yoke Ling, S.N.H. Hazlan, M. Azlan, S. Abdul Razak, T.A.D.A.-A. Tengku Din, N. Abdullah, N. Tagiling, V. Tee, M. Ehab Ayad, F.M. Zheng, E. El-Omar, Y.Y. Lee Beneficial Microbes, 2026 The Traditional Asian Diet (TAD) is characterised by high dietary fibre and functional foods. This study investigated TAD’s effects on meeting fibre requirements, gut microbiome, and faecal and urine metabolomes. A four-week randomised controlled trial was conducted among healthy Asian women allocated into the TAD group (n = 11) following a newly developed TAD program and the control group (n = 11). Assessments included dietary intake, gut health (symptoms, faecal form, frequency), serum fatty acids binding protein-2 (FABP-2) levels, faecal microbiome via 16s rRNA sequencing, and faecal and urine metabolites which were analysed using gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR), respectively. The TAD group showed significant increases in dietary fibre (), reduced fat (), and improved faecal form () compared to the control group. The TAD group was enriched with Parabacteroides merdae, while Bacteroides uniformis was more abundant in the control group. Individuals with baseline Prevotella copri showed its enrichment following TAD and higher butyrate levels, unlike the control group. The TAD led to lower urine levels of creatinine, dimethylamine, and phenethylamine compared to the control diet. In conclusion, the TAD program has proven beneficial effects in achieving dietary fibre, enriching the beneficial microbiota and metabolites, reducing harmful metabolites, and improving faecal form compared to a control diet. Clinical trial registration: NCT04885959, clinicaltrials.gov
The Milan Score Predicts Objective Gastroesophageal Reflux Disease in Patients With Type 2 Esophagogastric Junction Davide Ferrari, Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Ivan Kristo, Salvatore Tolone, Elisa Marabotto, Daniele Bernardi, Sebastian F. Schoppmann, Benjamin D. Rogers, Anthony Hobson, Jordan Haworth, Yeong Yeh Lee, Brian E. Louie, Takahiro Masuda, Megan L. Ivy, Pamela Milito, Erica Centorrino, Dimitrios Theodorou, Tania Triantafyllou, Andrea Pasta, Francesco Calabrese, Vincent Tee, Lorenzo Cusmai, Roberto Penagini, Marina Coletta, Edoardo Savarino, Emanuele Asti, C. Prakash Gyawali, Nicola De Bortoli Neurogastroenterology and Motility, 2026 IntroductionHigh‐resolution manometry (HRM) allows assessment of esophagogastric junction (EGJ) disruption. While type 3 EGJ predicts definitive gastroesophageal reflux disease (GERD), type 2 EGJ is less clearly implicated in GERD pathogenesis. This study aimed to characterize physiologic findings in type 2 EGJ to determine if the HRM‐based Milan Score can define GERD within type 2 EGJ.Methods535 patients with suspected GERD who underwent HRM and reflux monitoring were retrospectively analyzed. Clinical, HRM, and reflux study data were compared between the EGJ morphology subtypes, with objective GERD defined according to Lyon Consensus 2.0. The Milan Score, a novel metric that integrates ineffective esophageal motility, EGJ‐contractile integral, EGJ morphology, and straight leg raise response, was abnormal when ≥ 137 (risk rate 50% for GERD). Receiver operating characteristic (ROC) curve analysis was performed to assess the accuracy of the Milan Score to predict objective GERD.ResultsType 3 EGJ was associated with the highest rate of objective GERD, followed by type 2 and type 1 EGJ (p < 0.001), with a corresponding stepwise increase in AET from type 1 to 3 EGJ (p < 0.001). Type 2 EGJ with Milan Score < 137 resembled type 1 EGJ (objective GERD in 23.6% vs. 33.2%, p = 0.09), and type 2 EGJ with score ≥ 137 resembled type 3 EGJ (objective GERD in 88.2% vs. 78.8%, p = 0.11). On ROC analysis, the Milan Score had an area under the curve of 0.858.ConclusionWhile type 2 EGJ includes varying GERD severity, the Milan Score can segregate patients at risk for objective GERD.
Combined Lyon and Milan Scores Predict Gerd Management Outcome Better Than Either Score Alone or Their Individual Components Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Sara Boveri, Benjamin D. Rogers, Nicola De Bortoli, Anthony Hobson, Brian E. Louie, Yeong Yeh Lee, Salvatore Tolone, Elisa Marabotto, Jordan Haworth, Megan L. Ivy, Lorenzo Cusmai, Edoardo Campioli, Dimitrios Theodorou, Tania Triantafyllou, Andrea Pasta, Francesco Calabrese, Vincent Tee, Daniele Bernardi, Carlo Galdino Riva, Roberta De Maron, Enrique Coss‐Adame, Amit Patel, Emanuele Asti, Edoardo Savarino, C. Prakash Gyawali Alimentary Pharmacology and Therapeutics, 2025 BackgroundConfidence in gastro‐oesophageal reflux disease (GERD) diagnosis is crucial to improve outcomes from escalation of treatment. The Lyon score phenotypes patients through endoscopy and pH‐impedance (MII‐pH). The Milan score quantifies antireflux barrier through high‐resolution manometry (HRM) parameters.AimTo explore the relationship between the Lyon and Milan scores and their combined performance in predicting clinical outcomes.MethodsWe collected clinical and follow‐up data of consecutive patients with HRM and MII‐pH from nine centres. Clinical improvement was defined as a 50% reduction in global symptoms. The relationship between Lyon and Milan scores and the rate of patients improved in Lyon phenotypes and Milan categories were explored. The ability of the Lyon, Milan, DeMeester scores and acid exposure time (AET) in predicting outcomes was assessed through receiver operating characteristics (ROC) analysis.ResultsAmong 532 patients (50.6% female, age 50 years), 47.7% had pathologic GERD. A stepwise increase in the Milan score in Lyon phenotypes was observed. Sixty‐three patients had surgical treatment, and 131 medical. Clinical improvement in Lyon phenotypes Conclusive and Severe was 81% and 83%; in Milan categories very likely and extremely likely was 88.5% and 100%. If Lyon and Milan scores were positive, improvement was 89%; if discordant, 63%; if both negative, 19% (p < 0.001). ROC analysis showed an AUC of 0.790 for Lyon score, 0.835 for Milan score, 0.736 for DeMeester score and 0.741 for AET.ConclusionsThe Lyon and Milan scores outperformed AET and DeMeester scores in predicting outcomes in GERD patients. When concordant, they provide optimal predictive accuracy, guiding escalation of therapy.
Validation of Esophageal Global Symptom Severity as a Patient-Reported Outcome for Evaluation of Reflux Symptoms Walter W. Chan, Matthew Schroeder, Allyson Richardson, Neemit Shah, Mayssan Muftah, et al. American Journal of Gastroenterology, 2025 INTRODUCTION: Visual Analog Scales (VAS) are simple, easy for patients to comprehend, and require limited translation. We evaluated the value of esophageal global symptom severity (GSS) measured using VAS in assessing initial reflux symptom burden as compared with other validated questionnaires, esophageal symptom burden, and outcome after reflux management. METHODS: We analyzed pooled data from published historical cohorts of patients undergoing pH-impedance testing for reflux symptoms from 3 continents (North America, Europe, Asia). Univariate (Spearman correlation), multivariable (general linear regression), and receiver operating characteristic analyses were performed to compare GSS with validated symptom instruments including gastroesophageal reflux disease questionnaire (GERDQ), GERD health-related quality of life (GERD-HRQL), Reflux Symptom Index (RSI), and metrics from pH-impedance monitoring per Lyon Consensus 2.0. RESULTS: One thousand two hundred ninety-six patients (mean age 52.0 years, 61.9% female) were included: 937, 197, and 162 from North America, Europe, and Asia, respectively. GSS significantly correlated with GERDQ (R = 0.455), GERD-HRQL (R = 0.440), RSI (R = 0.491), acid exposure time (AET) (R = 0.158), and total reflux episodes (R = 0.161) ( P < 0.0001 for each comparison). The mean GSS was higher with abnormal GERDQ, GERD-HRQL, RSI, pathologic AET, and conclusive GERD per Lyon Consensus ( P < 0.0001 each comparison). On receiver operating characteristic analyses, GSS was noninferior to GERDQ, GERD-HRQL, and RSI in predicting pathologic AET and total reflux episodes, and conclusive GERD. Percentage improvement in GSS after antireflux treatment significantly correlated with change in GERDQ (R = 0.536, P < 0.0001) and treatment satisfaction (R = 0.532 P = 0.0002). On multivariable linear regression analyses, percentage change in GSS remained an independent predictor of both change in GERDQ (β = 0.813, P < 0.0001) and satisfaction with antireflux therapy (β = 1.90, P = 0.0006). DISCUSSION: GSS correlates with other validated reflux questionnaires and discriminates abnormal from normal reflux burden in patients with reflux symptoms. GSS change also reflects reflux treatment outcome and satisfaction. GSS is a useful addition to patient symptom assessment before and after GERD treatment.
Normal opening pressure lumbar puncture in cryptococcal meningitis complicated by a cerebral venous thrombosis: a case report and literature review Vincent Tee, Abdul Hakim Maiden, Fatimah Othman, Ping Sheng Chua, Mung Seong Wong Frontiers in Medicine, 2025 Cryptococcal meningitis (CM) is a severe fungal infection that primarily affects individuals with compromised immune systems, such as those living with HIV/AIDS or undergoing immunosuppressive therapy. Elevated intracranial pressure is a common complication of CM and remains an important diagnostic parameter in patients with CM. This report describes a case of CM complicated with cerebral venous thrombosis (CVT) in an immunocompetent patient residing in the southern region of Peninsular Malaysia. The diagnosis of CM was confirmed by cerebrospinal fluid (CSF) culture; however, the patient presented with normal opening pressure during lumbar puncture. The pathophysiology and factors of causality, together with their diagnostic challenges, are discussed.
Abnormal Milan Score and Compromised Esophageal Mucosal Integrity Stratify Gastroesophageal Reflux Disease Severity Marco Sozzi, Stefano Siboni, Pierfrancesco Visaggi, Benjamin D. Rogers, Anthony Hobson, Brian E. Louie, Yeong Yeh Lee, Salvatore Tolone, Ivan Kristo, Elisa Marabotto, Jordan Haworth, Megan L. Ivy, Dimitrios Theodorou, Tania Triantafyllou, Francesco Calabrese, Andrea Pasta, Vincent Tee, Lorenzo Cusmai, Carlo Galdino Riva, Daniele Bernardi, Takahiro Masuda, Roberto Penagini, Marina Coletta, Sebastian F. Schoppmann, Nicola De Bortoli, Emanuele L.G. Asti, Edoardo Vincenzo Savarino, C Prakash Gyawali Annals of Surgery, 2025 Objective: To explore the manometric characteristics of patients with severe GERD. To assess the role of HRM features in patients with adjunctive diagnostic Lyon 2.0 criteria and to create a GERD severity prediction model. Summary Background Data: GERD is a complex disorder with diagnostic challenges, as symptoms may not reflect disease severity. High-resolution manometry and the Milan Score numerically quantify the degree of anti-reflux barrier disruption in patients with GERD symptoms. Methods: An international prospective database of patients undergoing HRM and pH-impedance (MII-pH) for persistent GERD symptoms was queried. GERD was defined according to Lyon 2.0. Severe GERD was defined as either acid exposure time (AET)>12%, DeMeester score>50, grade C-D esophagitis or Barrett’s esophagus. Demographic, HRM and pH data were compared between groups (no GERD, non-severe GERD, severe GERD). The ability of the HRM and MII-pH variables in stratifying GERD severity was assessed using ordinal logistic regression. Results: Among 603 patients enrolled (median age 49.9 y, median body mass index 25.3 kg/m2, 49.5% females), 124 (20.6%) had non-severe and 142 (23.5%) had severe GERD. On ordinal logistic regression, hiatal hernia size and Milan Score category were independent predictors of GERD severity (OR 1.28 and 2.92). Patients with adjunctive Lyon 2.0 GERD evidence and those fulfilling any severe GERD criteria had significantly higher Milan Score (P<0.001). In the comprehensive HRM-MII-pH model, mean nocturnal baseline impedance (MNBI) and Milan Score category remained independent predictors of severe GERD (OR 4.17 and 1.61, P<0.001). Conclusions: MNBI and Milan Score are independently associated with severe GERD. The Milan Score is significantly higher in patients with pathologic adjunctive pH-impedance metrics.
The Milan score: A novel manometric tool for a more efficient diagnosis of gastro-esophageal reflux disease Stefano Siboni, Marco Sozzi, Ivan Kristo, Sara Boveri, Benjamin D. Rogers, Nicola De Bortoli, Anthony Hobson, Brian E. Louie, Yeong Yeh Lee, Salvatore Tolone, Elisa Marabotto, Pierfrancesco Visaggi, Jordan Haworth, Megan L. Ivy, Garrett Greenan, Takahiro Masuda, Roberto Penagini, Benedetta Barcella, Marina Coletta, Dimitrios Theodorou, Tania Triantafyllou, Chiara Facchini, Vincent Tee, Luigi Bonavina, Lorenzo Cusmai, Sebastian F. Schoppmann, Edoardo Savarino, Emanuele Asti, C. Prakash Gyawali United European Gastroenterology Journal, 2024 ObjectiveA definitive diagnosis of gastroesophageal reflux disease (GERD) depends on endoscopic and/or pH‐study criteria. However, high resolution manometry (HRM) can identify factors predicting GERD, such as ineffective esophageal motility (IEM), esophago‐gastric junction contractile integral (EGJ‐CI), evaluating esophagogastric junction (EGJ) type and straight leg raise (SLR) maneuver response. We aimed to build and externally validate a manometric score (Milan Score) to stratify the risk and severity of the disease in patients undergoing HRM for suspected GERD.MethodsA population of 295 consecutive patients undergoing HRM and pH‐study for persistent typical or atypical GERD symptoms was prospectively enrolled to build a model and a nomogram that provides a risk score for AET > 6%. Collected HRM data included IEM, EGJ‐CI, EGJ type and SLR. A supplemental cohort of patients undergoing HRM and pH‐study was also prospectively enrolled in 13 high‐volume esophageal function laboratories across the world in order to validate the model. Discrimination and calibration were used to assess model's accuracy. Gastroesophageal reflux disease was defined as acid exposure time >6%.ResultsOut of the analyzed variables, SLR response and EGJ subtype 3 had the highest impact on the score (odd ratio 18.20 and 3.87, respectively). The external validation cohort consisted of 233 patients. In the validation model, the corrected Harrel c‐index was 0.90. The model‐fitting optimism adjusted calibration slope was 0.93 and the integrated calibration index was 0.07, indicating good calibration.ConclusionsA novel HRM score for GERD diagnosis has been created and validated. The MS might be a useful screening tool to stratify the risk and the severity of GERD, allowing a more comprehensive pathophysiologic assessment of the anti‐reflux barrier.Trial registrationClinicalTrials.gov (Identifier: NCT05851482).
Structural equation models of health behaviour, psychological well-being, symptom severity and quality of life in abdominal bloating Nurzulaikha Abdullah, Yee Cheng Kueh, Garry Kuan, Mung Seong Wong, Vincent Tee, Tengku Ahmad Iskandar Tengku Alang, Nurhazwani Hamid, Yeong Yeh Lee Peerj, 2024 Background The objective of this study was to investigate the inter-relationship between psychosocial variables and their impact on symptom severity and quality of life (QoL) concerning abdominal bloating. Methods The study adopted a cross-sectional design with purposive sampling. Participants who consented and met the criteria for bloating based on the Rome IV classification completed designated questionnaires. Independent variables comprised health beliefs, intentions, health-promoting behaviors, social support, depression, and anxiety, while dependent variables included bloating severity (general and within 24 h) and QoL. Structural Equation Modeling (SEM) was conducted utilizing Mplus 8.0 to analyze the relationships between these factors. Results A total of 323 participants, with a mean age of 27.69 years (SD = 11.50), predominantly females (64.7%), volunteered to participate in the study. The final SEM model exhibited good fit based on various indices (CFI = 0.922, SRMR = 0.064, RMSEA (95% CI) = 0.048 (0.041–0.054), p-value = 0.714), with 15 significant path relationships identified. The model explained 12.0% of the variance in severity within 24 h, 6% in general severity, and 53.8% in QoL. Conclusion The findings underscore the significant influence of health beliefs, intentions, behaviors, social support, depression, and anxiety on symptom severity and QoL in individuals experiencing abdominal bloating.
Effects of Electronic Dance Music on Academic Performance among Medical Students: A Narrative Review Koo Thai Hau, , Vincent Tee, Garry Kuan, , and Education in Medicine Journal, 2024 Music always influences how a person thinks and communicates with others. Research on the relationship between music and education has been growing for several years. Some scholars suggest that listening to music may improve cognitive capabilities, while others believe that it may slow down complicated brain processes. Electronic dance music (EDM) is a subgenre of electronic music originally composed for use in bars, clubs and other venues that include dance-based amusement. Some scholars argue that EDM is a music style that benefits our brain activities, particularly their cognitive aspects. However, the use of EDM to enhance academic performance among students is still not widely practised globally. Furthermore, research on EDM usage among medical students is rarely conducted. Hence, this study aims to investigate EDM as a learning tool and discover whether it is helpful in improving medical students’ academic achievement and overall growth. The study consists of a narrative review conducted according to the Scale for the Assessment of Narrative Review Articles (SANRA). Literature searches were performed in the databases of PubMed, ResearchGate, ScienceDirect and Google Scholar for the period between September 2012 and November 2022. The review revealed limited research on the use of EDM as an instrument to enhance academic performance among medical students. However, existing studies suggest that EDM may have cognitive benefits and positively influence brain activities, particularly in the cognitive domain. Although EDM is commonly associated with leisure and entertainment settings, its potential for learning remains underexplored in the context of medical education.
Improving the Diagnostic Yield of High-Resolution Esophageal Manometry for GERD: The “Straight Leg-Raise” International Study Stefano Siboni, Ivan Kristo, Benjamin D. Rogers, Nicola De Bortoli, Anthony Hobson, Brian Louie, Yeong Yeh Lee, Vincent Tee, Salvatore Tolone, Elisa Marabotto, Pierfrancesco Visaggi, Jordan Haworth, Megan Ivy, Garrett Greenan, Chiara Facchini, Takahiro Masuda, Fumiaki Yano, Kyle Perry, Gokulakrishnan Balasubramanian, Dimitrios Theodorou, Tania Triantafyllou, Lorenzo Cusmai, Sara Boveri, Sebastian F. Schoppmann, C. Prakash Gyawali, Luigi Bonavina Clinical Gastroenterology and Hepatology, 2023
The milan score predicts objective gastroesophageal reflux disease in patients with type 2 esophagogastric junction D Ferrari, S Siboni, M Sozzi, P Visaggi, I Kristo, S Tolone, E Marabotto, ... Neurogastroenterology & Motility 38 (1), e14987 , 2026 2026 Citations: 11
Normal opening pressure lumbar puncture in cryptococcal meningitis complicated by a cerebral venous thrombosis: a case report and literature review V Tee, AH Maiden, F Othman, PS Chua, MS Wong Frontiers in Medicine 12, 1619155 , 2025 2025
Combined Lyon and Milan scores predict Gerd Management outcome better than either score alone or their individual components S Siboni, M Sozzi, P Visaggi, S Boveri, BD Rogers, N De Bortoli, ... Alimentary pharmacology & therapeutics 62 (7), 710-721 , 2025 2025 Citations: 15
Abnormal Milan score and compromised esophageal mucosal integrity stratify gastroesophageal reflux disease severity M Sozzi, S Siboni, P Visaggi, BD Rogers, A Hobson, BE Louie, YY Lee, ... Annals of surgery, 10.1097 , 2025 2025 Citations: 9
ASSESSING THE INTER-OBSERVER VARIABILITY OF HIGH-RESOLUTION MANOMETRY GERD-REALATED FEATURES AND MILAN SCORE M Sozzi, S Siboni, AR Latorre-Rodriguez, SK Mittal, E Marabotto, A Pasta, ... Gastroenterology 169 (1) , 2025 2025
789: THE LYON SCORE COMPLEMENTS THE MILAN SCORE IN PREDICTING OUTCOME FROM ESCALATION OF MEDICAL AND SURGICAL TREATMENT IN PATIENTS WITH PERSISTENT REFLUX SYMPTOMS S Siboni, M Sozzi, P Visaggi, BD Rogers, N De Bortoli, A Hobson, YY Lee, ... Gastroenterology 169 (1), S-184 , 2025 2025
The Milan Score is an effective manometric tool to predict gastroesophageal reflux in patients with laryngopharyngeal symptoms S Siboni, M Sozzi, P Visaggi, I Kristo, N De Bortoli, S Tolone, E Marabotto, ... Neurogastroenterology & Motility, e70015 , 2025 2025 Citations: 5
Effects of Traditional Asian Diet on dietary fibre requirement, gut microbiome composition, and faecal and urine metabolomes in healthy Asian women: a pilot study NF Sahran, CW Chong, IH Ismail, F Taib, PS Hoo, UD Palanisamy, ... Beneficial Microbes 17 (1), 47-60 , 2025 2025 Citations: 1
Application of Angklung Art-Based Intervention to the Elderly in Malaysia: Preliminary Research MAM Bakri, MK Sabran, A Ab Razak, V Tee, ASA Halim KUPAS SENI: Jurnal Seni Dan Pendidikan Seni 12 (2), 23-32 , 2024 2024 Citations: 2
Traditional Asian Diet Benefits on Gut Microbiome, Stool and Urine Metabolomes in Healthy Asian Women NF Sahran, LY Yeh, CC Wie, IH Ismail, F Taib, HP Sung, UD Palinasamy, ... JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 39, 111-111 , 2024 2024
Green Endoscopy and Sustainable Practices: A Scoping Review TH Koo, V Tee, YY Lee, NS Roslan, YS Ibrahim Journal of Digestive Endoscopy 15 (03), 184-191 , 2024 2024 Citations: 4
The Milan score: A novel manometric tool for a more efficient diagnosis of gastro‐esophageal reflux disease S Siboni, M Sozzi, I Kristo, S Boveri, BD Rogers, N De Bortoli, A Hobson, ... United European Gastroenterology Journal 12 (5), 552-561 , 2024 2024 Citations: 46
Structural equation models of health behaviour, psychological well-being, symptom severity and quality of life in abdominal bloating N Abdullah, YC Kueh, G Kuan, MS Wong, V Tee, TAIT Alang, N Hamid, ... PeerJ 12, e17265 , 2024 2024 Citations: 1
Implementation of chatbot technology in health care: protocol for a bibliometric analysis Z Ni, ML Peng, V Balakrishnan, V Tee, I Azwa, R Saifi, LRE Nelson, ... JMIR research protocols 13 (1), e54349 , 2024 2024 Citations: 31
Implementation of Chatbot Technology in health care: Protocol for a bibliometric analysis. JMIR Research Protocols, 13 Z Ni, ML Peng, V Balakrishnan, V Tee, I Azwa, R Saifi, LE Nelson, ... 2024 Citations: 5
Effects of Electronic Dance Music on Academic Performance among Medical Students: A Narrative Review. KT Hau, V Tee, G Kuan Education in Medicine Journal 16 (1) , 2024 2024 Citations: 5
Comparing Inter-Asian Differences in Chronic Pancreatitis: A Focus on South-East and South Asia (CPSEASA) M Unnisa, R Goud, A Patel, S Javvaji, M Reddy, R Mehta, M Rahaman, ... Pancreatology 23 (8), e24 , 2023 2023
Climate change and the esophagus: speculations on changing disease patterns as the world warms YY Lee, NS Roslan, V Tee, TH Koo, YS Ibrahim Current Gastroenterology Reports 25 (11), 280-288 , 2023 2023 Citations: 7
Diagnostic challenge in a case of foul-smelling vaginal discharge in a newly attained menarche girl V Tee, CW Ng, AA Ismail, NAH Che Hashim, NR Afendi Proceedings of Singapore Healthcare 32, 20101058231209188 , 2023 2023
Efficacy and safety of nab-paclitaxel in metastatic gastric cancer: a meta-analysis S Ahmad, L Lambuk, N Ahmed, A Mussa, V Tee, RA Mohd Idris, ... Nanomedicine 18 (24), 1733-1744 , 2023 2023 Citations: 14
MOST CITED SCHOLAR PUBLICATIONS
Formative evaluation of the acceptance of HIV prevention artificial intelligence chatbots by men who have sex with men in Malaysia: focus group study ML Peng, JA Wickersham, FL Altice, R Shrestha, I Azwa, X Zhou, ... JMIR Formative Research 6 (10), e42055 , 2022 2022.0 Citations: 47
The Milan score: A novel manometric tool for a more efficient diagnosis of gastro‐esophageal reflux disease S Siboni, M Sozzi, I Kristo, S Boveri, BD Rogers, N De Bortoli, A Hobson, ... United European Gastroenterology Journal 12 (5), 552-561 , 2024 2024.0 Citations: 46
Improving the diagnostic yield of high-resolution esophageal manometry for GERD: The “straight leg-raise” international study S Siboni, I Kristo, BD Rogers, N De Bortoli, A Hobson, B Louie, YY Lee, ... Clinical Gastroenterology and Hepatology 21 (7), 1761-1770. e1 , 2023 2023.0 Citations: 37
Deep tendon reflex: the tools and techniques. What surgical neurology residents should know O Lin-Wei, LLS Xian, VTW Shen, CY Chuan, SA Halim, ARI Ghani, Z Idris, ... The Malaysian Journal of Medical Sciences: MJMS 28 (2), 48 , 2021 2021.0 Citations: 32
Implementation of chatbot technology in health care: protocol for a bibliometric analysis Z Ni, ML Peng, V Balakrishnan, V Tee, I Azwa, R Saifi, LRE Nelson, ... JMIR research protocols 13 (1), e54349 , 2024 2024.0 Citations: 31
Barriers and facilitators to pre-exposure prophylaxis by men who have sex with men and community stakeholders in Malaysia AO Rosen, JA Wickersham, FL Altice, A Khati, I Azwa, V Tee, ... International Journal of Environmental Research and Public Health 20 (9), 5669 , 2023 2023.0 Citations: 21
Dentinal tubule penetration of bioceramic-based versus epoxy resin-based root canal sealers: a systematic review and meta-analysis GSS Lin, DZK Chan, JZ Leong, Z Kan, WM Xuan, V Tee Giornale Italiano Di Endodonzia 36 (2) , 2022 2022.0 Citations: 17
Combined Lyon and Milan scores predict Gerd Management outcome better than either score alone or their individual components S Siboni, M Sozzi, P Visaggi, S Boveri, BD Rogers, N De Bortoli, ... Alimentary pharmacology & therapeutics 62 (7), 710-721 , 2025 2025.0 Citations: 15
Efficacy and safety of nab-paclitaxel in metastatic gastric cancer: a meta-analysis S Ahmad, L Lambuk, N Ahmed, A Mussa, V Tee, RA Mohd Idris, ... Nanomedicine 18 (24), 1733-1744 , 2023 2023.0 Citations: 14
Cross-cultural adaptation and validation of the Malay version of sports motivation scale-II NS Chin, GC Liew, YC Kueh, HA Hashim, V Tee, G Kuan International journal of environmental research and public health 18 (21), 11694 , 2021 2021.0 Citations: 12
The milan score predicts objective gastroesophageal reflux disease in patients with type 2 esophagogastric junction D Ferrari, S Siboni, M Sozzi, P Visaggi, I Kristo, S Tolone, E Marabotto, ... Neurogastroenterology & Motility 38 (1), e14987 , 2026 2026.0 Citations: 11
Formative evaluation of the acceptance of HIV prevention artificial intelligence Chatbots by men who have sex with men in Malaysia: focus group study. JMIR Form Res. 2022; 6 … ML Peng, JA Wickersham, FL Altice, R Shrestha, I Azwa, X Zhou, ... Citations: 10
Abnormal Milan score and compromised esophageal mucosal integrity stratify gastroesophageal reflux disease severity M Sozzi, S Siboni, P Visaggi, BD Rogers, A Hobson, BE Louie, YY Lee, ... Annals of surgery, 10.1097 , 2025 2025.0 Citations: 9
A prospective comparison of UK and Malaysian patients with irritable bowel syndrome in secondary care KH Chuah, CJ Black, V Tee, SZ Lim, WX Hian, NF Sahran, YY Lee, ... Alimentary pharmacology & therapeutics 58 (2), 168-174 , 2023 2023.0 Citations: 9
Climate change and the esophagus: speculations on changing disease patterns as the world warms YY Lee, NS Roslan, V Tee, TH Koo, YS Ibrahim Current Gastroenterology Reports 25 (11), 280-288 , 2023 2023.0 Citations: 7
Hepatoprotective effects of silymarin in management of liver injury caused by tuberculosis treatment YY Lee, V Tee Drugs in Context 12 , 2023 2023.0 Citations: 7
Formative evaluation of the acceptance of HIV prevention artificial intelligence chatbots by men who have sex with men in Malaysia: focus group study. JMIR Form Res. 2022 Oct … ML Peng, JA Wickersham, FL Altice, R Shrestha, I Azwa, X Zhou, ... Citations: 7
The Milan Score is an effective manometric tool to predict gastroesophageal reflux in patients with laryngopharyngeal symptoms S Siboni, M Sozzi, P Visaggi, I Kristo, N De Bortoli, S Tolone, E Marabotto, ... Neurogastroenterology & Motility, e70015 , 2025 2025.0 Citations: 5
Implementation of Chatbot Technology in health care: Protocol for a bibliometric analysis. JMIR Research Protocols, 13 Z Ni, ML Peng, V Balakrishnan, V Tee, I Azwa, R Saifi, LE Nelson, ... 2024.0 Citations: 5
Effects of Electronic Dance Music on Academic Performance among Medical Students: A Narrative Review. KT Hau, V Tee, G Kuan Education in Medicine Journal 16 (1) , 2024 2024.0 Citations: 5
