Dr. Hareesha Nagarajappa
@mangaloreuniversity.ac.in
INSPIRE Fellow, DST, India, Research Scholar, Department of Chemistry, F.M.K.M.C. College, Constituent College of Mangalore University Madikeri, Karnataka, India.
Mangalore University Madikeri, Karnataka, India.
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Kanthappa Bhimaraya, Jamballi G. Manjunatha, Hareesha Nagarajappa, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpää
Elsevier BV
J. G. Manjunatha, N. Prinith Subbaiah, N. Hareesha, C. Raril, Ammar M. Tighezza, and Munirah D. Albaqami
Springer Science and Business Media LLC
J. L. Nikhil, J. G. Manjunatha, N. Hareesha, B. Kanthappa, C. S. Karthik, P. Mallu, and Zeid A. ALOthman
Springer Science and Business Media LLC
Pemmatte A. Pushpanjali, Jamballi G. Manjunatha, Nagarajappa Hareesha, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpää
Wiley
AbstractAn inexpensive and efficient sensor was developed for the electrochemical analysis of the antihistamine drug cetirizine (CTZ). The active sites on the bare carbon nanotube paste electrode surface were improved by the electropolymerization of poly(Glutamine). This modified electrode enhances the electrochemical response of the examining molecule. The study was conducted using a cyclic voltammetry technique in phosphate buffer saline of physiological pH 7.0 at a scan rate of 0.1 V/s. The developed electrode possesses increased conductance and declined overpotential for the determination of CTZ. At the optimized conditions, the detection limit was evaluated by obtaining the current response of CTZ at the varied concentration, and it was obtained as 0.12 μM. The poly glutamine modified carbon nanotube paste electrode was successfully applied to determine CTZ in tablet and human urine samples with acceptable recovery.
N. Hareesha, J.G. Manjunatha, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpää
Elsevier BV
B. Kanthappa, J. G. Manjunatha, N. Hareesha, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpää
Wiley
N. Hareesha, J. G. Manjunatha, C. Raril, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpää
Springer Science and Business Media LLC
Girish Tigari, Jamballi G. Manjunatha, Hareesha Nagarajappa, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpaa
Springer Science and Business Media LLC
J. G. Manjunatha, B. Kanthappa, N. Hareesha, C. Raril, Ammar M. Tighezza, and Munirah D. Albaqami
Springer Science and Business Media LLC
Kanthappa Bhimaraya, Jamballi G. Manjunatha, Hareesha Nagarajappa, Ahmed Muteb Aljuwayid, Mohamed A. Habila, and Mika Sillanpaa
Springer Science and Business Media LLC
Madikeri Manjunth Charithra, Jamballi Gangadarappa gowda Manjunatha, Nagarajappa Hareesha, Subbaiah Nambudamada Prinith, Doddarsikere K. Ravishankar, and Huligerepura J. Arpitha
Bentham Science Publishers Ltd.
Abstract: The electrochemical detection of neurotransmitters is an imperative application in the field of analytical chemistry. The recent development in the electrochemical sensors based on carbon electrodes is very important due to their sensitivity and simplicity. Using the carbon-based sensor for the electrochemical analysis of the neurotransmitters is a simple method. Furthermore, these above methods provide high sensitivity, are user-friendly, and are well-matched with the concept of green chemistry. In light of this matter, this review article is devoted to the voltammetric detection of neurotransmitters by using the carbon-based electrode. Here, we survey the accomplishments in the determination of numerous neurotransmitters with high selectivity and sensitivity provided using carbon-based electrodes. Attention is concentrated on the working electrode and its promising modification which is vital for further analysis of the neurotransmitters.
N. Hareesha, J.G. Manjunatha, T. Girish, and Zeid A. ALOthman
Informa UK Limited
Balliamada M. Amrutha, Jamballi G. Manjunatha, Hareesha Nagarajappa, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpää
MDPI AG
Rutin (RU) is one of the best-known natural antioxidants with various physiological functions in the human body and other plant species. In this work, an efficient voltammetric sensor to detect RU in food samples was explicated using a poly (glutamic acid)-modified graphene paste electrode (PGAMGPE). In order to detect RU, the proposed sensor diminishes material resistance and overpotential while increasing kinetic rate, peak currents, and material conductance. Using differential pulse voltammetry (DPV) and cyclic voltammetry (CV), the analysing efficiency of a PGAMGPE and a Bare graphene paste electrode (BGPE) was evaluated in 0.2 M phosphate buffer (PB) at an ideal pH of 6.5. in a potential window of −0.25 V to 0.6 V. Electrochemical impedance spectroscopy (EIS) was used to analyse the prepared electrode materials’ conductivity, charge transfer resistance, and the kinetics of electron transport. Field emission scanning electron microscopy (FE-SEM) images were considered to compare the exterior morphology of the PGAMGPE and the BGPE. It was discovered that the PGAMGPE and the BGPE have electroactive surfaces of 0.062 cm2 and 0.04 cm2, respectively. It was determined that two protons and two electrons participated in the redox process. The resultant limit of detection (LOD) was found to be 0.04 µM and 0.06 µM, respectively, using DPV and CV methods. In spite of common interferents such as metal ions and chemical species, the developed sensor’s selectivity for RU detection was impressive. For the simultaneous analysis of RU in the presence of caffeine (CF), the PGAMGPE affords a good electrochemical nature for RU with good selectivity. Due to the good stability, repeatability, reproducibility, and ease of use of the present RU sensor, it is useful for real sample analysis such as food and medicinal samples with recovery ranging from 94 to 100%.
Kanthappa Bhimaraya, Jamballi G. Manjunatha, Hareesha Nagarajappa, Ammar M. Tighezza, Munirah D. Albaqami, and Mika Sillanpää
MDPI AG
Certain dyes are deleterious to the biological system, including animals and plants living in the water sources, soil sources, and so on. Thus, the analysis of these dyes requires a potent, quick, and cost-effective approach to the environmental samples. The present research work shows a modest, low-cost, and eco-friendly electrochemical device based on poly(dl-phenylalanine)-layered carbon nanotube paste electrode (P(PAN)LCNTPE) material for indigo carmine (ICN) detection in the presence of tartrazine. The cyclic voltammetric, field emission scanning electron microscopy, and electrochemical impedance spectroscopic methods were operated for the detection of the redox nature of ICN and electrode material surface activities, respectively. In better operational circumstances, P(PAN)LCNTPE provided better catalytic activity for the redox action of ICN than the bare carbon nanotube paste electrode. The P(PAN)LCNTPE showed good electrochemical activity during the variation of ICN concentrations ranging from 0.2 µM to 10.0 µM with improved peak current, and the limit of detection was about 0.0216 µM. Moreover, the P(PAN)LCNTPE material was performed as a sensor of ICN in a tap water sample and shows adequate stability, repeatability, and reproducibility.
N. Hareesha, J.G. Manjunatha, Zeid A. Alothman, and Mika Sillanpää
Elsevier BV
Hareesha Nagarajappa, Jamballi G. Manjunatha, Abdullah A. Al‐Kahtani, Ammar M. Tighezza, and Narges Ataollahi
Wiley
Girish Tigari, J. G. Manjunatha, Edwin D’ Souza, C. Raril, N. Hareesha, and M. M. Charithra
Springer Science and Business Media LLC
Jamballi G. Manjunatha, Girish Tigari, Hareesha Nagarajappa, and Nambudumada S. Prinith
International Association of Physical Chemists (IAPC)
Various carbon-based sensors (graphene, carbon nanotubes, graphite, pencil graphite, glassy carbon, etc.) have distinctive behavior and a broad range of importance for identifying sex hormones like estriol, estradiol, estrone, progesterone, and testosterone. The current review emphasizes voltammetric, amperometric, and electrochemical impedance spectroscopic methods for detecting some of these hormones. The existence, structural aspects, nature, and biological importance of each hormone were analyzed in detail and their analysis with different electroanalytical methods was considered. Unique methodologies and innovations of electrochemical sensors for hormones based on carbon materials modified by different agents were examined. In this review, the interaction among various sensor materials and analytes in different supporting electrolyte media is premeditated. The most important significances of the electroanalytical methodologies were discussed based on sensor selectivity, sensitivity, stability, the limit of detection, repeatability, and reproducibility.
P.A. Pushpanjali, J.G. Manjunatha, N. Hareesha, B.M. Amrutha, C. Raril, Zeid A. ALOthman, Amer M. Alanazi, and Anup Pandith
Elsevier BV
P. A. Pushpanjali, J. G. Manjunatha, N. Hareesha, T. Girish, Abdullah A. Al-Kahtani, Ammar Mohamed Tighezza, and Narges Ataollahi
Springer Science and Business Media LLC
B. M. Amrutha, J. G. Manjunatha, A. S. Bhatt, N. Hareesha, Abdullah A. Al-Kahtani, Ammar Mohamed Tighezza, and Narges Ataollahi
Springer Science and Business Media LLC
N. Hareesha, J. G. Manjunatha, P. A. Pushpanjali, N. Prinith Subbaiah, M. M. Charithra, N. Sreeharsha, S. M. Basheeruddin Asdaq, and Md. Khalid Anwer
Springer Science and Business Media LLC
M. M. Charithra, Jamballi G Manjunatha, N. S. Prinith, P. A. Pushpanjali, T. Girish, and N. Hareesha
Informa UK Limited
ABSTRACT As an antibiotic, tinidazole (TNZ) is usually consumed to reduce the bacterial infection; thus, qualitative determination of the TNZ is very significant. Thus, in this article, the development of voltammetric sensor based on poly-threonine-modified carbon nanotube-mixed graphene paste electrode (PTRMCNTMGPE) for the detection of TNZ was reported. The PTRMCNTMGPE displayed a boosted electrocatalytic effect regarding the voltammetric signal of the TNZ (pH 7.0) compared to the bare electrode. The morphology of the proposed electrodes was characterised by field emission scanning electron microscopy. The charge transfer resistance of the designed electrode was studied through electrochemical impedance spectroscopy. The impact of pH and effect of scan rate was studied. The scan rate study reveals the reduction process of the TNZ was controlled by diffusion. The designed electrode yielded low detection limit (0.2 µM) for TNZ. The proposed electrode exhibited a good reproducibility, repeatability, selectivity and an antifouling feature. The practicability of the developed sensor was explored by detecting the TNZ in tablet and blood serum samples.
N. Hareesha and J. G. Manjunatha
Springer Science and Business Media LLC
AbstractThe current study explicates the electro-oxidation behavior of formoterol fumarate (FLFT) in the presence of uric acid (UA) on the surface of poly thiazole yellow-G (TY-G) layered multi-walled carbon nanotube paste electrode (MWCNTPE). The modified (Poly(TY-G)LMWCNTPE) and unmodified (MWCNTPE) electrode materials were characterized through electrochemical impedance spectroscopy (EIS), field emission scanning electron microscopy (FE-SEM), and cyclic voltammetry (CV) approaches. The characterization data confirms the good conducting and electrocatalytic nature with more electrochemical active sites on the Poly(TY-G)LMWCNTPE than MWCNTPE towards the FLFT analysis in the presence of UA. Poly(TY-G)LMWCNTPE easily separates the two drugs (FLFT and UA) even though they both have nearer oxidation peak potential. The electro-catalytic activity of the developed electrode is fast and clear for FLFT electro-oxidation in 0.2 M phosphate buffer (PB) of pH 6.5. The Poly(TY-G)LMWCNTPE offered a well-resolved peak with the highest electro-oxidation peak current at the peak potential of 0.538 V than MWCNTPE. The potential scan rate and oxidation peak growth time studies show the electrode reaction towards FLFT electro-oxidation is continued through a diffusion-controlled step. The variation of concentration of FLFT in the range from 0.2 to 1.5 µM (absence of UA) and 3.0 to 8.0 μM (presence of UA) provides a good linear relationship with increased peak current and a lower limit of detection (LOD) values of 0.0128 µM and 0.0129 µM, respectively. The prepared electrode gives a fine recovery for the detection of FLFT in the medicinal sample with acceptable repeatability, stability, and reproducibility.
Nambudumada S. Prinith, Jamballi G. Manjunatha, and Nagarajappa Hareesha
Springer Science and Business Media LLC