Nicola Dinapoli

Scopus Publications

Inguinal CTV contouring in anal cancer: comparative validation of inguinal lymph nodes contouring guidelines and implications for consensus
Viola De Luca, Stefania Manfrida, Natalia Barogi, Flavia De Giacomo, Raffaella Michela Rinaldi, Bruno Fionda, Roberta Bertolini, Giuditta Chiloiro, Rosa Autorino, Gabriella Macchia, Nicola Dinapoli, Christopher L.Hallemeier, Allison E. Garda, Maria Antonietta Gambacorta
Clinical and Translational Radiation Oncology, 2026
Background and purpose: Contouring Inguinal lymph nodes (ILNs) in anal squamous cell cancer (ASCC) remains challenging. Accurate delineation is essential to optimize treatment efficacy with sparing of organs at risk (OaRs). Garda et al. proposed a contouring guideline based on the anatomical distribution of inguinal lymphadenopathy. This study evaluates their effectiveness in ensuring adequate ILNs coverage. Materials and methods: We retrospectively analyzed ASCC patients with radiologically positive inguinal lymph nodes treated with IMRT in our institution between 2015 and 2024. ILNs were mapped relative to the femoral vessels and delineated based on the Garda's guidelines. Descriptive analyses were conducted. Results: Among 46 patients with positive ILNs, 27 (59%) had cT3-T4 stage and 27 (59%) had bilateral inguinal nodal involvement. Overall, 203 ILNs were analyzed: 88% (178 nodes) were anteromedial to the femoral vessels. Garda's CTV encompassed 182 nodes (90%), while 22 nodes (11%) across 14 patients (30%) were not covered. Most of the uncovered nodes were in the superolateral region (n = 15, 7% of all nodes), whereas 6 nodes (3%) from six patients were identified in the inferior region. Only one node was found in the superomedial quadrant, while no nodes were located posteriorly. Conclusions: These findings validate the proposed guidelines, confirming their effectiveness in reducing unnecessary irradiation of the posterolateral quadrant. However, coverage gaps highlight the need for further refinements to optimize target delineation. These findings offer disease-specific evidence to inform the harmonization of inguinal CTV delineation and support the development of standardized, consensus-based contouring protocols.
Which is the best timing to assess response after chemoradiation in locally advanced cervical cancer (BRILACC)?
Rosa Autorino, Gabriella Macchia, Luca Russo, Nicola Dinapoli, Valentina Lancellotta, Nicolò Bizzarri, Maria Gabriella Ferrandina, Maura Campitelli, Viola De Luca, Roberta Giannini, Raffaella Michela Rinaldi, Evis Sala, Benedetta Gui, Maria Antonietta Gambacorta
Strahlentherapie Und Onkologie, 2026
PURPOSE: The goal is to investigate the best time point for assessing radiological complete response after exclusive chemoradiation in locally advanced cervical cancer (LACC). This is a retrospective single-center study. MATERIALS AND METHODS: Seventy-nine patients with LACC, stage IB3-IVA FIGO 2018 treated between January and December 2020 were retrospectively analyzed. All patients received external beam radiotherapy (45 Gy in 25 daily fractions ± simultaneous boost to lymph nodes), and interventional radiotherapy (IRT, 28 Gy/twice/weekly) with concurrent chemotherapy. The radiological complete response evaluation was examined using magnetic resonance imaging (MRI) at three timepoints: (i) before IRT, at the end of external beam radiotherapy, (ii) 3 months following the completion of IRT and (iii) 6 months after IRT. Seventy-nine patients were included. RESULTS: At the three timepoints, the complete response rate increased with 21, 53, and 59 patients reporting a complete response at MRI scan, respectively. Seven patients with partial response at the second assessment had complete response 6 months after treatment completion, overall resulting in 80% clinical complete response. CONCLUSIONS: Our findings suggest that 6 months following the end of exclusive treatment for LACC patients is the best time to detect complete radiological response (measured by MRI scan) after chemoradiation. Waiting this period of time before conclusively assessing response would allow for the inclusion of patients who have not yet fully responded at 3 months, while avoiding the performance of salvage therapies too early.
Brief clinical exposure boosts radiation oncology awareness among Italian medical students
Raffaella Michela Rinaldi, Mariangela Massaccesi, Rosa Autorino, Nicola Dinapoli, Federica Finetti, Monica La Rocca, Maria Antonietta Gambacorta
Journal of Radiotherapy in Practice, 2026
Introduction: Radiation oncology (RO) plays a central role in modern cancer treatment. However, in Italy, this specialty remains under-represented in medical education, with limited awareness among students and many residency positions going unfilled. The gap between the importance of the discipline and student interest suggests a need to better integrate RO into medical training. Innovation: To assess the impact of early exposure, we conducted a pilot educational intervention involving 54th-year medical students. Participants completed a questionnaire before and after a six-hour clinical rotation in an RO department. The rotation included ward shadowing and introductory sessions on the role of the radiation oncologist. Discussion: At baseline, only 50% of students could describe the role of a radiation oncologist, and fewer than 10% were considering the specialty. Post-rotation, all students demonstrated an understanding of the profession. Positive perceptions of workload, safety and career prospects increased significantly ( p < 0.01). The proportion of students expressing interest in pursuing RO rose modestly from 8% to 12%, while those definitively excluding it dropped from 40% to 36%. These findings suggest that even brief exposure can correct misconceptions and enhance receptiveness towards the field. Recommendations: While a single half-day experience can meaningfully improve awareness and perceptions of RO, it is unlikely to drive major changes in career choices on its own. To translate greater understanding into actual recruitment, medical schools should implement more sustained and structured RO experiences throughout the curriculum.
Managing unplanned radiotherapy interruptions in Italy: results from an AIRO survey
Francesco Deodato, Alba Fiorentino, Donato Pezzulla, Gabriella Macchia, Stefania Manfrida, Nicola Dinapoli, Mattia Falchetto Osti, Giuseppe Sanguineti, Alessio Giuseppe Morganti, Elvio Grazioso Russi
Clinical and Translational Oncology, 2026
Background Radiation oncology (RO) is essential in cancer treatment. Unplanned interruptions reduce tumor control, yet no validated management guidelines exist. The Italian Association of Radiation and Clinical Oncology (AIRO) conducted a national survey to assess the prevalence, causes, and management strategies for RT interruptions across Italy. Methods This cross-sectional survey was conducted between April and June 2022. A 34-question survey was emailed to directors of all Italian ROT centers, covering: (1) demographic and institutional characteristics; (2) radiobiological knowledge of ROT interruptions; (3) clinical management and compensation strategies. Results A total of 104 centers responded. Respondents had a median age of 57 years (range 34–74), and most worked in General Hospitals (64%). Centers had a median of 2 LINACs (range 1–6), with 16% operating only one LINAC. 96% of radiation oncologists (Ros) considered ROT interruptions a critical issue, particularly in curative (51%) and adjuvant (29%) settings. 42% defined an interruption of > 5 days as critical, and 63% believed treatment phase did not influence impact. 29% of ROs followed formal guidelines [e.g., Royal College of Radiographers (RCR)]. The main causes of interruptions were LINAC breakdowns (22%), toxicity (22%), and patient compliance issues (22%). 24% of ROs followed codified procedures for managing interruptions; 84% regularly monitored treatment breaks. Dose recovery strategies: 28% always compensated, 59% occasionally compensated, primarily by increasing total dose (48%) or working on Saturdays (20%). Conclusion This study reveals variability in ROT interruption management, stressing the need for AIRO guidelines, collaboration, and modern radiobiological integration.
Early post-operative NI-RADS predicts recurrence and survival in high-risk oral cavity squamous cell carcinoma undergoing adjuvant radiotherapy
Mariangela Massaccesi, Marco Panfili, Rosalinda Calandrelli, Silvia Longo, Francesco Pastore, Francesco Miccichè, Calogero Casà, Stefano Settimi, Dario Antonio Mele, Nicola Dinapoli, Ciro Mazzarella, Simona Gaudino, Luca Tagliaferri, Jacopo Galli, Maria Antonietta Gambacorta, Giovanni Almadori
Radiologia Medica, 2026
Purpose To evaluate the prognostic value of the Neck Imaging Reporting and Data Systems (NI-RADS) in early post-operative imaging for predicting recurrence and survival outcomes in high-risk oral cavity squamous cell carcinoma (SCC) patients undergoing post-operative radiotherapy (PORT). Methods This retrospective study included 84 patients with high-risk oral cavity SCC who were scheduled for PORT after radical surgery between January 2013 and May 2024. Early imaging with contrast-enhanced CT or MRI was performed within 12 weeks post-surgery and scored using the NI-RADS system. Associations between NI-RADS scores, recurrence, and survival outcomes were analyzed using Kaplan–Meier and Cox proportional hazards models. Results Although NI-RADS was originally designed for post-treatment surveillance, we applied it to early post-operative imaging as an exploratory risk-stratification tool. NI-RADS scores significantly predicted regional disease-free survival (DFS) and overall survival (OS). Patients with higher NI-RADS T and N scores had poorer outcomes. Multivariable analysis confirmed early NI-RADS T as an independent predictor of OS ( p = 0.01). Interobserver agreement for NI-RADS classifications was strong (Weighted Kappa: T = 0.837, N = 0.855). Although higher radiotherapy doses were administered to patients with NI-RADS 2–3 scores, these patients demonstrated worse outcomes, reflecting aggressive disease. Conclusion Early application of NI-RADS in post-operative imaging provides valuable prognostic insights, enabling risk stratification and tailored management in high-risk oral cavity SCC patients. Streamlining imaging workflows and exploring alternative therapeutic strategies for high-risk groups may further optimize outcomes.
Adaptive volumetric-modulated arc therapy with central GTV dose escalation for chemotherapy-ineligible p16-negative oropharyngeal cancer with bulky nodal metastasis: A case report
Mariangela Massaccesi, Francesco Pastore, Silvia Longo, Gerardina Stimato, Antonella Martino, Stefania Manfrida, Vincenzo Frascino, Rosa Autorino, Nicola Dinapoli, Maria Antonietta Gambacorta
Journal of Radiotherapy in Practice, 2025
Introduction: Oropharyngeal squamous cell carcinoma (SCC) is a common type of head and neck cancer often linked to tobacco, alcohol use, and, in youngers, HPV infection. Standard care for locally advanced SCC involves radiotherapy (RT) and cisplatin, (total doses of 66–70Gy in 30–35fractions). However, some patients with significant comorbidities cannot tolerate chemotherapy, requiring alternative approaches. We present a case of a 66-year-old male with p16-negative oropharyngeal SCC and bulky cervical nodal metastasis, ineligible for chemotherapy. Materials & Methods: The patient was treated using adaptive volumetric modulated arc therapy (VMAT) with simultaneous integrated boost (SIB) and central gross tumor volume (GTV) dose escalation. This approach delivered up to 72Gy to the central GTV in 30 fractions; 66 Gy in 30 fractions to the high-risk area; 60Gy in 30 fractions to the intermediate-risk area; 54 Gy in 30 fractions to the low-risk area. Results: An epithelolysis (grade 3) led to a four-day treatment pause. A mid-treatment CT showed tumor shrinkage, reducing the nodal GTV volume from 107to 33cc, prompting adaptive planning to optimize dose distribution and reduce toxicity. The patient completed RT without further interruptions. At six months post-treatment, no recurrence or severe toxicities were detected and four years post-treatment, the patient remains in complete remission without significant late toxicity. Conclusions: This case demonstrates the effectiveness of VMAT with SIB in delivering accelerated radiotherapy to a bulky nodal lesion in a patient with p16-negative oropharyngeal SCC unfit for chemotherapy; This allowed for tumor control while minimizing exposure to critical structure.
High-Tailored Anal canal Radiotherapy (HIT-ART): Long term results of MR image-guided interventional radiotherapy (brachytherapy) boost
Luca Tagliaferri, Stefania Manfrida, Bruno Fionda, Nicola Dinapoli, Brunella Barbaro, Viola De Luca, Elisa Placidi, Roberta Bertolini, Fabio Marazzi, Valentina Lancellotta, Vincenzo Frascino, Alessio Giuseppe Morganti, Maria Antonietta Gambacorta
Brachytherapy, 2025
PURPOSE: The aim of this study is to investigate the outcomes in terms of survival, treatment compliance and toxicity in a cohort of patients treated with personalized chemoradiation (RCT) followed by image guided Interventional Radiotherapy (IG-IRT), stratified by clinical baseline stage and treatment response. METHODS AND MATERIALS: We analyzed patients with histologically proven squamous anal carcinoma treated using intensity modulated radiation therapy (IMRT) with curative intent, and IRT boost. External beam radiation was delivered using personalized IMRT technique with a simultaneous-integrated boost (SIB) to deliver 45 to 55 Gy in 25 fractions according to clinical stage. After the end of the RCT patients underwent clinical and imaging re-evaluation, and according to initial stage of disease and tumor response, a radiotherapy boost was administered through IG-IRT, performing MRI with IRT applicator on site (trans-anal position) and defining GTV on MRI imaging. All patients' treatments and outcomes data were collected by an internal database. The endpoints were in terms of overall treatment time (OTT), toxicity, clinical complete response (cCR), locoregional failure (LRF), colostomy free survival, overall survival (OS) and disease-free survival (DFS). Univariate survival analysis with Kaplan- Meier curves was performed to allow between-group comparison. RESULTS: 73 patients treated between February 2012 and January 2023 were included in the analysis. 72.6 % were female, with a median age of 65.4 years (range 39.1-89). 62 were staged T2-T4 (T2 42.5.5%, T3 19.2%, T4 27.4%) and 50 (68.5%) had positive nodes. Combined RCT was administered mainly using mitomycin C and 5-fluorouracil. The mean dose received by patients was 50 Gy; after a median time of 43 days (range 9-128) a sequential boost dose was delivered in 1-2 fractions (median dose of 4 Gy). OTT median was 85 days (range 44-225). The median follow-up period was 50.6 months. LRF was 17.8%, and at 3 and 5 years LC was 80.1% and 77.2%, CFS was 80.5 and 77.8%, DFS was 79.3% and 75.9% and OS 95.1%, 84.3% and 61.4% at 10 years. Moreover, we verified that OS was higher in patients who had an OTT lower than 93 days. Toxicity was acceptable: 45.2% of patients experienced a G1-G2 abdominal discomfort (only 5.5% had G3). CONCLUSIONS: Our experience confirms that MR Image Guided Interventional Radiotherapy boost is a feasible treatment option with a significant impact on outcomes.
E_N_T_R_O_P_Y: Monocentric analysis of rectal cancer radio-chemotherapy treatment in patients of young age
E. Meldolesi, A. Nicolì, N. Dinapoli, G. Chiloiro, A. Romano, R. Menghi, R. Persiani, F. Pacelli, C. Coco, C. Ratto, S. Manfrida, L. Boldrini, B. Corvari, M.A. Gambacorta
Clinical and Translational Radiation Oncology, 2025
Purpose//objectives: A disproportionate incidence's increase of rectal cancer in patients younger than 50 years of age. The ESMO and NCCN recommendations are not age-specific and the literature is poor and conflicting. We decided to examine patients with rectal cancer treated in our centre in the last 15 years with curative neoadjuvant radiochemotherapy comparing outcomes in the two groups under and over 55 years old. Materials/methods: 788 rectal cancer patients were enrolled in this monocentric retrospective observational study (523 =>55 years and 265 < 55). All patients received neoadjuvant chemoradiation treatment. R statistical software v.4.1.3 was used for the entire analysis. The outcomes were death, local recurrence, and new distant metastases. Survival analysis was performed using the Kaplan-Meier method and the Log-rank was used to compare the two groups. Results: All patients were classified in different risk groups, according to the ESMO 2017 rectal cancer clinical practice guidelines. 88 % of patients under 55 years old at the diagnosis belonged to the bad or advanced risk groups with an equal division. In patients over 55 years old, there was a clear dominance of the advanced risk class (62 % of the total). In multivariate analysis, OS and DFS decrease with increasing age and ESMO risk group. The other variables in multivariate were not significant. For Both OS, DFS and MFS, the curves separated significantly at 55 years of age, with a prevalence of metastasis development in the older group. Conclusion: Elderly patients have a prevalence of advanced disease. Younger patients seem having a better OS at 3 and 5 years. ESMO risk group and age were the only variables affecting OS and DFS. Young patients have better MFS and DFS at 2 and 5 years than patients older than 55 years. The addition of oxaliplatin to fluoropyrimidine-based neoadjuvant chemotherapy resulted not significant in both groups.
Gender role in radiotherapy: psychosocial differences between males and females during cancer care: Single-centre report on adult and paediatric oncological patients
L. Dinapoli, N. Dinapoli, E. Marconi, S. Chiesa, C. Mazzarella, M. Massaccesi, S. Longo, F. Marazzi, V. Masiello, R. Autorino, V. De Luca, L. Boldrini, G. Chiloiro, S. Manfrida, A. Mastronuzzi, E. Meldolesi, L. Sani, V. Frascino, F. Miccichè, V. Valentini, L. Tagliaferri, G. F. Colloca, D. P. R. Chieffo, M. A. Gambacorta
Strahlentherapie Und Onkologie, 2025
Resilience and spiritual well-being as resources for coping with radiotherapy and surviving in patients with glioblastoma
Loredana Dinapoli, Morena Caliandro, Silvia Chiesa, Elisa Marconi, Nikola Dino Capocchiano, Ciro Mazzarella, Francesco Beghella Bartoli, Serena Bracci, Mario Balducci, Daniela Pia Rosaria Chieffo, Alba Fiorentino, Vincenzo Valentini, Luca Tagliaferri, Maria Antonietta Gambacorta, Nicola Dinapoli
Palliative and Supportive Care, 2024
Objectives The primary aims of this multicenter, prospective observational study were to investigate spiritual well-being, resilience, and psychosocial distress in an Italian sample of glioblastoma patients undergoing radiochemotherapy. The secondary aim was to explore the influence of demographic, clinical, and psychological characteristics on survival. Methods The assessment was conducted only once, within the first week of radiochemotherapy treatment. Spiritual well-being was evaluated by the Functional Assessment of Chronic Illness Therapy-Spiritual Well-being (FACIT-Sp-12), and religious/spiritual beliefs and practices were evaluated by the System of Belief Inventory. Resilience was evaluated by the Connor−Davidson Resilience Scale (CD-RISC). Psychosocial distress was evaluated the by Distress Thermometer and Hospital Anxiety Depression Scale. We conducted an univariable analysis of overall survival (OS) using data from the most recent follow-up available, considering demographic and clinical variables that could influence survival. Follow-up was defined as either the time of death or the latest follow-up visit recorded. Results We recruited 104 patients, and the median follow-up time was 18.3 months. “Distressed” patients had lower scores than “not distressed” patients on the FACIT-Sp-12 and CD-RISC. While OS was not significant according to the FACIT-Sp-12 threshold, the Kaplan−Meier log-rank test was 0.05 according to the CD-RISC threshold. Among demographic variables, age showed significant associations with OS (p = 0.011). Resilience showed significant associations with OS (p = 0.025). Significance of results Data showed that high spiritual well-being was associated with high resilience and an absence of psychosocial distress in our sample of glioblastoma patients undergoing radiochemotherapy. Patients with greater resilience survived longer than those with lesser resilience. Profiling spiritual well-being and resilience in glioblastoma patients undergoing radiochemotherapy can be seen as a resource to identify novel characteristics to improve clinical take-in-charge of glioblastoma patients.
Magnetic Resonance Imaging Guided Radiation Therapy for Splenomegaly: Clinical Experiences and Technical Tips
Angela Romano, Lorenzo Placidi, Luca Boldrini, Giuditta Chiloiro, Nicola Dinapoli, Matteo Galetto, Ciro Mazzarella, Guenda Meffe, Matteo Nardini, Giulia Panza, Sara Ceglie, Patrizia Chiusolo, Elena Rossi, Luca Indovina, Maria Antonietta Gambacorta
Advances in Radiation Oncology, 2024
Psychological Experiences of Parents of Pediatric Cancer Patients during and after COVID-19 Pandemic
Antonella Guido, Elisa Marconi, Laura Peruzzi, Nicola Dinapoli, Gianpiero Tamburrini, Giorgio Attinà, Alberto Romano, Palma Maurizi, Stefano Mastrangelo, Silvia Chiesa, Maria Antonietta Gambacorta, Antonio Ruggiero, Daniela Pia Rosaria Chieffo
Cancers, 2024
The Image Biomarker Standardization Initiative: Standardized Convolutional Filters for Reproducible Radiomics and Enhanced Clinical Insights
Philip Whybra, Alex Zwanenburg, Vincent Andrearczyk, Roger Schaer, Aditya P. Apte, Alexandre Ayotte, Bhakti Baheti, Spyridon Bakas, Andrea Bettinelli, Ronald Boellaard, Luca Boldrini, Irène Buvat, Gary J. R. Cook, Florian Dietsche, Nicola Dinapoli, Hubert S. Gabryś, Vicky Goh, Matthias Guckenberger, Mathieu Hatt, Mahdi Hosseinzadeh, Aditi Iyer, Jacopo Lenkowicz, Mahdi A. L. Loutfi, Steffen Löck, Francesca Marturano, Olivier Morin, Christophe Nioche, Fanny Orlhac, Sarthak Pati, Arman Rahmim, Seyed Masoud Rezaeijo, Christopher G. Rookyard, Mohammad R. Salmanpour, Andreas Schindele, Isaac Shiri, Emiliano Spezi, Stephanie Tanadini-Lang, Florent Tixier, Taman Upadhaya, Vincenzo Valentini, Joost J. M. van Griethuysen, Fereshteh Yousefirizi, Habib Zaidi, Henning Müller, Martin Vallières, Adrien Depeursinge
Radiology, 2024
Spindle-cell myoepithelioma: A rare case in a finger of a 15-year-old boy
Silvia Pietramala, Antonio Tulli, Gianfranco Merendi, Camillo Fulchignoni, Michela Quirino, Nicola Di Napoli, Luca Tagliaferri, Antonio Pagliei
Hand Surgery and Rehabilitation, 2023
May we routinely spare hippocampal region in primary central nervous system lymphoma during whole brain radiotherapy?
Ciro Mazzarella, Silvia Chiesa, Lucrezia Toppi, Stefan Hohaus, Simona Gaudino, Francesco D’Alo, Nicola Dinapoli, Resta Davide, Tiziano Zinicola, Serena Bracci, Antonella Martino, Francesco Beghella Bartoli, Elisabetta Lepre, Roberta Bertolini, Silvia Mariani, Cesare Colosimo, Vincenzo Frascino, Gian Carlo Mattiucci, Maria Antonietta Gambacorta, Vincenzo Valentini, Mario Balducci
Radiation Oncology, 2023
Active bone marrow segmentation based on computed tomography imaging in anal cancer patients: A machine-learning-based proof of concept
C. Fiandra, S. Rosati, F. Arcadipane, N. Dinapoli, M. Fato, P. Franco, E. Gallio, D. Scaffidi Gennarino, P. Silvetti, S. Zara, U. Ricardi, G. Balestra
Physica Medica, 2023
MRI-derived radiomics to guide post-operative management of glioblastoma: Implication for personalized radiation treatment volume delineation
S. Chiesa, R. Russo, F. Beghella Bartoli, I. Palumbo, G. Sabatino, M. C. Cannatà, R. Gigli, S. Longo, H. E. Tran, L. Boldrini, N. Dinapoli, C. Votta, D. Cusumano, F. Pignotti, M. Lupattelli, F. Camilli, G. M. Della Pepa, G. Q. D’Alessandris, A. Olivi, M. Balducci, C. Colosimo, M. A. Gambacorta, V. Valentini, C. Aristei, S. Gaudino
Frontiers in Medicine, 2023
In response to Topkan E. et al. letter (Radiother Oncol. 2022;174:132. https://doi.org/10.1016/j.radonc.2022.07.017)
Nicola Dinapoli, Mariangela Massaccesi, Francesco Miccichè
Radiotherapy and Oncology, 2023
Local tuning of radiomics-based model for predicting pathological response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer
Bin Tang, Jacopo Lenkowicz, Qian Peng, Luca Boldrini, Qing Hou, Nicola Dinapoli, Vincenzo Valentini, Peng Diao, Gang Yin, Lucia Clara Orlandini
BMC Medical Imaging, 2022
Applicability of a pathological complete response magnetic resonance-based radiomics model for locally advanced rectal cancer in intercontinental cohort
Luca Boldrini, Jacopo Lenkowicz, Lucia Clara Orlandini, Gang Yin, Davide Cusumano, Giuditta Chiloiro, Nicola Dinapoli, Qian Peng, Calogero Casà, Maria Antonietta Gambacorta, Vincenzo Valentini, Jinyi Lang
Radiation Oncology, 2022
Could 18-FDG PET-CT Radiomic Features Predict the Locoregional Progression-Free Survival in Inoperable or Unresectable Oesophageal Cancer?
Berardino De Bari, Loriane Lefevre, Julie Henriques, Roberto Gatta, Antoine Falcoz, Pierre Mathieu, Christophe Borg, Nicola Dinapoli, Hatem Boulahdour, Luca Boldrini, Vincenzo Valentini, Dewi Vernerey
Cancers, 2022
A predictive nomogram for trismus after radiotherapy for head and neck cancer
Mariangela Massaccesi, Nicola Dinapoli, Valentina Fuga, Cosimo Rupe, Marco Panfili, Rosalinda Calandrelli, Stefano Settimi, Michela Olivieri, Francesco Beghella Bartoli, Ciro Mazzarella, Silvia Longo, Carlo Lajolo, Luca Boldrini, Maria Antonietta Gambacorta, Vincenzo Valentini, Francesco Miccichè
Radiotherapy and Oncology, 2022
The Role of Simultaneous Integrated Boost in Locally Advanced Rectal Cancer Patients with Positive Lateral Pelvic Lymph Nodes
Elisa Meldolesi, Giuditta Chiloiro, Roberta Giannini, Roberta Menghi, Roberto Persiani, Barbara Corvari, Claudio Coco, Stefania Manfrida, Carlo Ratto, Viola De Luca, Luigi Sofo, Sara Reina, Antonio Crucitti, Valeria Masiello, Nicola Dinapoli, Vincenzo Valentini, Maria Antonietta Gambacorta
Cancers, 2022
EROS 2.0 study: evaluation of two interventional radiotherapy (brachytherapy) schedules for endometrial cancer: a comparison of late vaginal toxicity rates
Valentina Lancellotta, Gabriella Macchia, Nicola Dinapoli, Rosa Autorino, Maura Campitelli, Alessia Nardangeli, Alessandra Salvati, Bruno Fionda, Calogero Casà, Patrizia Cornacchione, Angeles Rovirosa, György Kovács, Alessio Giuseppe Morganti, Maria Gabriella Ferrandina, Maria Antonietta Gambacorta, Luca Tagliaferri
Radiologia Medica, 2022
The impact of radiomics in diagnosis and staging of pancreatic cancer
Calogero Casà, Antonio Piras, Andrea D’Aviero, Francesco Preziosi, Silvia Mariani, Davide Cusumano, Angela Romano, Ivo Boskoski, Jacopo Lenkowicz, Nicola Dinapoli, Francesco Cellini, Maria Antonietta Gambacorta, Vincenzo Valentini, Gian Carlo Mattiucci, Luca Boldrini
Therapeutic Advances in Gastrointestinal Endoscopy, 2022
A Predictive Model of 2yDFS During MR-Guided RT Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients
Giuditta Chiloiro, Luca Boldrini, Francesco Preziosi, Davide Cusumano, Poonam Yadav, Angela Romano, Lorenzo Placidi, Jacopo Lenkowicz, Nicola Dinapoli, Michael F. Bassetti, Maria Antonietta Gambacorta, Vincenzo Valentini
Frontiers in Oncology, 2022
Radiotherapy during the COVID-19: a review about management and treatment strategies
Lucrezia Bernabucci, Patrizia Cornacchione, Luca Boldrini, Danilo Pasini, Loredana Dinapoli, Lana Smiljanic, Vincenzo Valentini, Nicola Dinapoli
Reports of Practical Oncology and Radiotherapy, 2022
Does restaging MRI radiomics analysis improve pathological complete response prediction in rectal cancer patients? A prognostic model development
Giuditta Chiloiro, Davide Cusumano, Paola de Franco, Jacopo Lenkowicz, Luca Boldrini, Davide Carano, Brunella Barbaro, Barbara Corvari, Nicola Dinapoli, Martina Giraffa, Elisa Meldolesi, Riccardo Manfredi, Vincenzo Valentini, Maria Antonietta Gambacorta
Radiologia Medica, 2022
Psychological Impact of COVID-19 on Parents of Pediatric Cancer Patients
Antonella Guido, Elisa Marconi, Laura Peruzzi, Nicola Dinapoli, Gianpiero Tamburrini, Giorgio Attinà, Mario Balducci, Vincenzo Valentini, Antonio Ruggiero, Daniela Pia Rosaria Chieffo
Frontiers in Psychology, 2021
Personalised support of brain tumour patients during radiotherapy based on psychological profile and quality of life
Loredana Dinapoli, Silvia Chiesa, Nicola Dinapoli, Roberto Gatta, Francesco Beghella Bartoli, Serena Bracci, Ciro Mazzarella, Maria Zoe Sanfilippo, Giovanni Sabatino, Simona Gaudino, Giuseppe Maria Della Pepa, Vincenzo Frascino, Vincenzo Valentini, Mario Balducci
Supportive Care in Cancer, 2021
Personalized Treatment Planning Automation in Prostate Cancer Radiation Oncology: A Comprehensive Dosimetric Study
Savino Cilla, Carmela Romano, Vittoria E. Morabito, Gabriella Macchia, Milly Buwenge, Nicola Dinapoli, Luca Indovina, Lidia Strigari, Alessio G. Morganti, Vincenzo Valentini, Francesco Deodato
Frontiers in Oncology, 2021
Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
Claudio Votta, Davide Cusumano, Luca Boldrini, Nicola Dinapoli, Lorenzo Placidi, Gabriele Turco, Marco Valerio Antonelli, Veronica Pollutri, Angela Romano, Luca Indovina, Vincenzo Valentini
Physics and Imaging in Radiation Oncology, 2021
Pretreatment mri radiomics based response prediction model in locally advanced cervical cancer
Benedetta Gui, Rosa Autorino, Maura Miccò, Alessia Nardangeli, Adele Pesce, Jacopo Lenkowicz, Davide Cusumano, Luca Russo, Salvatore Persiani, Luca Boldrini, Nicola Dinapoli, Gabriella Macchia, Giuseppina Sallustio, Maria Antonietta Gambacorta, Gabriella Ferrandina, Riccardo Manfredi, Vincenzo Valentini, Giovanni Scambia
Diagnostics, 2021
The Multidimensional Assessment for Pediatric Patients in Radiotherapy (M.A.P.-RT) Tool for Customized Treatment Preparation: RADAR Project
Silvia Chiesa, Elisa Marconi, Nicola Dinapoli, Maria Zoe Sanfilippo, Antonio Ruggiero, Angela Mastronuzzi, Giulia Panza, Annalisa Serra, Mariangela Massaccesi, Antonella Cacchione, Francesco Beghella Bartoli, Daniela Pia Rosaria Chieffo, Maria Antonietta Gambacorta, Vincenzo Valentini, Mario Balducci
Frontiers in Oncology, 2021
Correction to: Hypofractionated sequential radiotherapy boost: a promising strategy in inoperable locally advanced pancreatic cancer patients (Journal of Cancer Research and Clinical Oncology, (2021), 147, 3, (661-667), 10.1007/s00432-020-03411-7)
Gian Carlo Mattiucci, Luca Boldrini, Alessia Nardangeli, Andrea D’Aviero, Milly Buwenge, Francesco Cellini, Francesco Deodato, Nicola Dinapoli, Vincenzo Frascino, Gabriella Macchia, Alessio Giuseppe Morganti, Vincenzo Valentini
Journal of Cancer Research and Clinical Oncology, 2021
Hypofractionated sequential radiotherapy boost: a promising strategy in inoperable locally advanced pancreatic cancer patients
Gian Carlo Mattiucci, Luca Boldrini, Alessia Nardangeli, Andrea D’Aviero, Milly Buwenge, Francesco Cellini, Francesco Deodato, Nicola Dinapoli, Vincenzo Frascino, Gabriella Macchia, Alessio Giuseppe Morganti, Vincenzo Valentini
Journal of Cancer Research and Clinical Oncology, 2021
A field strength independent MR radiomics model to predict pathological complete response in locally advanced rectal cancer
Davide Cusumano, Gert Meijer, Jacopo Lenkowicz, Giuditta Chiloiro, Luca Boldrini, Carlotta Masciocchi, Nicola Dinapoli, Roberto Gatta, Calogero Casà, Andrea Damiani, Brunella Barbaro, Maria Antonietta Gambacorta, Luigi Azario, Marco De Spirito, Martijn Intven, Vincenzo Valentini
Radiologia Medica, 2021
Predicting radiotherapy impact on late bladder toxicity in prostate cancer patients: An observational study
Francesco Catucci, Anna Rita Alitto, Carlotta Masciocchi, Nicola Dinapoli, Roberto Gatta, Antonella Martino, Ciro Mazzarella, Bruno Fionda, Vincenzo Frascino, Antonio Piras, Andrea D’Aviero, Francesco Preziosi, Giovanni Palazzoni, Vincenzo Valentini, Giovanna Mantini
Cancers, 2021
PSYCHOLOGICAL IMPACTS DURING COVID-19 QUARANTINE IN ITALIAN FEMALE CANCER PATIENTS: A MONO-INSTITUTIONAL EXPERIENCE
Journal of Cancer Rehabilitation, 2021
Delta Radiomics Can Predict Distant Metastasis in Locally Advanced Rectal Cancer: The Challenge to Personalize the Cure
Giuditta Chiloiro, Pablo Rodriguez-Carnero, Jacopo Lenkowicz, Calogero Casà, Carlotta Masciocchi, Luca Boldrini, Davide Cusumano, Nicola Dinapoli, Elisa Meldolesi, Davide Carano, Andrea Damiani, Brunella Barbaro, Riccardo Manfredi, Vincenzo Valentini, Maria Antonietta Gambacorta
Frontiers in Oncology, 2020
Template-based automation of treatment planning in advanced radiotherapy: a comprehensive dosimetric and clinical evaluation
Savino Cilla, Anna Ianiro, Carmela Romano, Francesco Deodato, Gabriella Macchia, Milly Buwenge, Nicola Dinapoli, Luca Boldrini, Alessio G. Morganti, Vincenzo Valentini
Scientific Reports, 2020
A deep learning approach to generate synthetic CT in low field MR-guided adaptive radiotherapy for abdominal and pelvic cases
Davide Cusumano, Jacopo Lenkowicz, Claudio Votta, Luca Boldrini, Lorenzo Placidi, Francesco Catucci, Nicola Dinapoli, Marco Valerio Antonelli, Angela Romano, Viola De Luca, Giuditta Chiloiro, Luca Indovina, Vincenzo Valentini
Radiotherapy and Oncology, 2020
Stability of dosomics features extraction on grid resolution and algorithm for radiotherapy dose calculation
L. Placidi, J. Lenkowicz, D. Cusumano, L. Boldrini, N. Dinapoli, V. Valentini
Physica Medica, 2020
Radiotherapy imaging: An unexpected ally in fighting COVID 19 pandemic
Luca Boldrini, Nicola Dinapoli, Vincenzo Valentini
Radiotherapy and Oncology, 2020
The image biomarker standardization initiative: Standardized quantitative radiomics for high-throughput image-based phenotyping
Alex Zwanenburg, Martin Vallières, Mahmoud A. Abdalah, Hugo J. W. L. Aerts, Vincent Andrearczyk, Aditya Apte, Saeed Ashrafinia, Spyridon Bakas, Roelof J. Beukinga, Ronald Boellaard, Marta Bogowicz, Luca Boldrini, Irène Buvat, Gary J. R. Cook, Christos Davatzikos, Adrien Depeursinge, Marie-Charlotte Desseroit, Nicola Dinapoli, Cuong Viet Dinh, Sebastian Echegaray, Issam El Naqa, Andriy Y. Fedorov, Roberto Gatta, Robert J. Gillies, Vicky Goh, Michael Götz, Matthias Guckenberger, Sung Min Ha, Mathieu Hatt, Fabian Isensee, Philippe Lambin, Stefan Leger, Ralph T.H. Leijenaar, Jacopo Lenkowicz, Fiona Lippert, Are Losnegård, Klaus H. Maier-Hein, Olivier Morin, Henning Müller, Sandy Napel, Christophe Nioche, Fanny Orlhac, Sarthak Pati, Elisabeth A.G. Pfaehler, Arman Rahmim, Arvind U.K. Rao, Jonas Scherer, Muhammad Musib Siddique, Nanna M. Sijtsema, Jairo Socarras Fernandez, Emiliano Spezi, Roel J.H.M. Steenbakkers, Stephanie Tanadini-Lang, Daniela Thorwarth, Esther G.C. Troost, Taman Upadhaya, Vincenzo Valentini, Lisanne V. van Dijk, Joost van Griethuysen, Floris H.P. van Velden, Philip Whybra, Christian Richter, Steffen Löck
Radiology, 2020
On the accuracy of bulk synthetic CT for MR-guided online adaptive radiotherapy
Davide Cusumano, Lorenzo Placidi, Stefania Teodoli, Luca Boldrini, Francesca Greco, Silvia Longo, Francesco Cellini, Nicola Dinapoli, Vincenzo Valentini, Marco De Spirito, Luigi Azario
Radiologia Medica, 2020
Abscopal effect and interventional oncology: State of art and future perspectives
Bruno Fionda, Mariangela Massaccesi, Luca Tagliaferri, N. Dinapoli, Roberto Iezzi, et al.
European Review for Medical and Pharmacological Sciences, 2020
SKIN-COBRA (Consortium for Brachytherapy data Analysis) ontology: The first step towards interdisciplinary standardized data collection for personalized oncology in skin cancer
Valentina Lancellotta, Jose Luis Guinot, Bruno Fionda, Agata Rembielak, Alessandro Di Stefani, Stefano Gentileschi, Francesco Federico, Ernesto Rossi, Benjamin Guix, Artur Jan Chyrek, Arenas Meritxell, Silvia Villalba, Giuseppe Colloca, Nicola Dinapoli, Carlotta Masciocchi, Jacopo Lenkowicz, Nicola Capocchiano, Andrea Damiani, Vincenzo Valentini, Gyorgy Kovacs, Luca Tagliaferri
Journal of Contemporary Brachytherapy, 2020
INTERACTS (INTErventional Radiotherapy ACtive Teaching School) consensus conference on sarcoma interventional radiotherapy (brachytherapy) endorsed by AIRO (Italian Association of Radiotherapy and Clinical Oncology)
Luca Tagliaferri, Andrea Vavassori, Valentina Lancellotta, Vitaliana De Sanctis, Cristiana Vidali, Calogero Casà, Cynthia Aristei, Domenico Genovesi, Barbara Jereczek-Fossa, Alessio Giuseppe Morganti, György Kovács, Jose Luis Guinot, Agata Rembielak, Daniela Greto, Maria Gambacorta, Vincenzo Valentini, Vittorio Donato, Renzo Corvò, Stefano Magrini, Lorenzo Livi, Consensus Board
Journal of Contemporary Brachytherapy, 2020
A new frontier of image guidance: Organs at risk avoidance with MRI-guided respiratory-gated intensity modulated radiotherapy: Technical note and report of a case
Mariangela Massaccesi, Davide Cusumano, Luca Boldrini, Nicola Dinapoli, Bruno Fionda, Stefania Teodoli, Luigi Azario, Gian Carlo Mattiucci, Mario Balducci, Francesco Cellini, Vincenzo Valentini
Journal of Applied Clinical Medical Physics, 2019
Towards a modular decision support system for radiomics: A case study on rectal cancer
Roberto Gatta, Mauro Vallati, Nicola Dinapoli, Carlotta Masciocchi, Jacopo Lenkowicz, Davide Cusumano, Calogero Casá, Alessandra Farchione, Andrea Damiani, Johan van Soest, Andre Dekker, Vincenzo Valentini
Artificial Intelligence in Medicine, 2019
Efficacy of an eye movement desensitization and reprocessing (EMDR) intervention for a head and neck cancer patient with intolerable anxiety undergoing radiotherapy
Loredana Dinapoli, Mariangela Massaccesi, Giuseppe Colloca, Angela Tenore, Nicola Dinapoli, Vincenzo Valentini
Psycho Oncology, 2019
Delta radiomics for rectal cancer response prediction with hybrid 0.35 T magnetic resonance-guided radiotherapy (MRgRT): a hypothesis-generating study for an innovative personalized medicine approach
Luca Boldrini, Davide Cusumano, Giuditta Chiloiro, Calogero Casà, Carlotta Masciocchi, Jacopo Lenkowicz, Francesco Cellini, Nicola Dinapoli, Luigi Azario, Stefania Teodoli, Maria Antonietta Gambacorta, Marco De Spirito, Vincenzo Valentini
Radiologia Medica, 2019
Identification of the most significant magnetic resonance imaging (MRI) radiomic features in oncological patients with vertebral bone marrow metastatic disease: a feasibility study
Laura Filograna, Jacopo Lenkowicz, Francesco Cellini, Nicola Dinapoli, Stefania Manfrida, Nicola Magarelli, Antonio Leone, Cesare Colosimo, Vincenzo Valentini
Radiologia Medica, 2019
Magnetic Resonance, Vendor-independent, Intensity Histogram Analysis Predicting Pathologic Complete Response After Radiochemotherapy of Rectal Cancer
Nicola Dinapoli, Brunella Barbaro, Roberto Gatta, Giuditta Chiloiro, Calogero Casà, Carlotta Masciocchi, Andrea Damiani, Luca Boldrini, Maria Antonietta Gambacorta, Michele Dezio, Gian Carlo Mattiucci, Mario Balducci, Johan van Soest, Andre Dekker, Philippe Lambin, Claudio Fiorino, Carla Sini, Francesco De Cobelli, Nadia Di Muzio, Calogero Gumina, Paolo Passoni, Riccardo Manfredi, Vincenzo Valentini
International Journal of Radiation Oncology Biology Physics, 2018
Hypofractionated stereotactic radiotherapy for oligometastatic patients: developing of a response predictive model
Barbara Diletto, Nicola Dinapoli, Silvia Chiesa, Gian Carlo Mattiucci, Vincenzo Frascino, Carmelo Anile, Cesare Colosimo, Vincenzo Valentini, Mario Balducci
Medical Oncology, 2018
Assessing the conformity to clinical guidelines in oncology: An example for the multidisciplinary management of locally advanced colorectal cancer treatment
Jacopo Lenkowicz, Roberto Gatta, Carlotta Masciocchi, Calogero Casà, Francesco Cellini, Andrea Damiani, Nicola Dinapoli, Vincenzo Valentini
Management Decision, 2018
A new standardized data collection system for interdisciplinary thyroid cancer management: Thyroid COBRA
Luca Tagliaferri, Carlo Gobitti, Giuseppe Ferdinando Colloca, Luca Boldrini, Eleonora Farina, Carlo Furlan, Fabiola Paiar, Federica Vianello, Michela Basso, Lorenzo Cerizza, Fabio Monari, Gabriele Simontacchi, Maria Antonietta Gambacorta, Jacopo Lenkowicz, Nicola Dinapoli, Vito Lanzotti, Renzo Mazzarotto, Elvio Russi, Monica Mangoni
European Journal of Internal Medicine, 2018
Hybrid Tri-Co-60 MRI radiotherapy for locally advanced rectal cancer: An in silico evaluation
Luca Boldrini, Elisa Placidi, Nicola Dinapoli, Luigi Azario, Francesco Cellini, Mariangela Massaccesi, Silvia Chiesa, Maria Antonietta Gambacorta, Gian Carlo Mattiucci, Danila Piccari, Stefania Teodoli, Marco De Spirito, Vincenzo Valentini
Technical Innovations and Patient Support in Radiation Oncology, 2018
How can radiomics improve clinical choices?
Elisa Meldolesi, Nicola Dinapoli, Roberto Gatta, Andrea Damiani, Vincenzo Valentini, Alessandra Farchione
Multidisciplinary Management of Rectal Cancer Questions and Answers, 2018
Fractal-based radiomic approach to predict complete pathological response after chemo-radiotherapy in rectal cancer
Davide Cusumano, Nicola Dinapoli, Luca Boldrini, Giuditta Chiloiro, Roberto Gatta, Carlotta Masciocchi, Jacopo Lenkowicz, Calogero Casà, Andrea Damiani, Luigi Azario, Johan Van Soest, Andre Dekker, Philippe Lambin, Marco De Spirito, Vincenzo Valentini
Radiologia Medica, 2018
Preliminary data analysis in healthcare multicentric data mining: A privacy-preserving distributed approach
A. Damiani, C. Masciocchi, L. Boldrini, R. Gatta, N. Dinapoli, J. Lenkowicz, G. Chiloiro, M. Gambacorta, L. Tagliaferri, R. Autorino, M. Pagliara, M. Blasi, J. V. Soest, A. Dekker, V. Valentini
Journal of E Learning and Knowledge Society, 2018
Ent cobra ontology: the covariates classification system proposed by the Head & Neck and Skin GEC-ESTRO Working Group for interdisciplinary standardized data collection in head and neck patient cohorts treated with interventional radiotherapy (brachytherapy)
Luca Tagliaferri, Ashwini Budrukkar, Jacopo Lenkowicz, Mauricio Cambeiro, Francesco Bussu, Jose Luis Guinot, Guido Hildebrandt, Bengt Johansson, Jens E. Meyer, Peter Niehoff, Angeles Rovirosa, Zoltán Takácsi-Nagy, Luca Boldrini, Nicola Dinapoli, Vito Lanzotti, Andrea Damiani, Roberto Gatta, Bruno Fionda, Valentina Lancellotta, Tamer Soror, Rafael Martìnez Monge, Vincenzo Valentini, György Kovács
Journal of Contemporary Brachytherapy, 2018
Radiomics based analysis to predict local control and survival in hepatocellular carcinoma patients treated with volumetric modulated arc therapy
Luca Cozzi, Nicola Dinapoli, Antonella Fogliata, Wei-Chung Hsu, Giacomo Reggiori, Francesca Lobefalo, Margarita Kirienko, Martina Sollini, Davide Franceschini, Tiziana Comito, Ciro Franzese, Marta Scorsetti, Po-Ming Wang
BMC Cancer, 2017
Beyond geometrical overlap: A dosimetrical evaluation of automated volumes adaptation (DEA) in head and neck replanning
Gian Carlo Mattiucci, Luca Boldrini, Lorenzo Placidi, Luigi Azario, Nicola Dinapoli, Giuditta Chiloiro, Danilo Pasini, Danila Piccari, Maria Antonietta Gambacorta, Mario Balducci, Giovanna Mantini, Vincenzo Valentini
Technical Innovations and Patient Support in Radiation Oncology, 2017
Modelling tumour volume variations in head and neck cancer: Contribution of magnetic resonance imaging for patients undergoing induction chemotherapy
N. Dinapoli, T. Tartaglione, F. Bussu, R. Autorino, F. Miccichè, M. Sciandra, E. Visconti, C. Colosimo, G. Paludetti, V. Valentini
Acta Otorhinolaryngologica Italica, 2017
Radiomics for rectal cancer
Nicola Dinapoli, Calogero Casà, Brunella Barbaro, Giuditta Valentina Chiloiro, Andrea Damiani, Marialuisa Di Matteo, Alessandra Farchione, Maria Antonietta Gambacorta, Roberto Gatta, Vito Lanzotti, Carlotta Masciocchi, Vincenzo Valentini
Translational Cancer Research, 2016
Automatic segmentation software in locally advanced rectal cancer: READY (REsearch program in Auto Delineation sYstem)-RECTAL 02: prospective study
Maria A. Gambacorta, Luca Boldrini, Chiara Valentini, Nicola Dinapoli, Gian C. Mattiucci, Giuditta Chiloiro, Danilo Pasini, Stefania Manfrida, Nicola Caria, Bruce D. Minsky, Vincenzo Valentini
Oncotarget, 2016
Oncologic outcome of hypopharyngeal carcinoma treated with different modalities at 2 different university hospitals
Francesco Bussu, Federica Mura, Francesco Miccichè, Giulia Bertino, Antonio Occhini, Giovanni Almadori, Jacopo Galli, Manlio Pandolfini, Roberto Gallus, Rosa Autorino, Maria Lavinia Guidi, Nicola Dinapoli, Vincenzo Valentini, Gaetano Paludetti, Marco Benazzo
Head and Neck, 2016
Comparison of interstitial brachytherapy and surgery as primary treatments for nasal vestibule carcinomas
Francesco Bussu, Luca Tagliaferri, Giancarlo Mattiucci, Claudio Parrilla, Nicola Dinapoli, Francesco Miccichè, Alberto Artuso, Jacopo Galli, Giovanni Almadori, Vincenzo Valentini, Gaetano Paludetti
Laryngoscope, 2016
RadioBio data: A moddicom module to predict tumor control probability and normal tissue complication probability in radiotherapy
Nicola Dinapoli, Anna Rita Alitto, Mauro Vallati, Rosa Autorino, Roberto Gatta, Luca Boldrini, Andrea Damiani, Giovanna Mantini, Vincenzo Valentini
Healthinf 2016 9th International Conference on Health Informatics Proceedings Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies Biostec 2016, 2016
Standardized data collection to build prediction models in oncology: A prototype for rectal cancer
Elisa Meldolesi, Johan van Soest, Andrea Damiani, Andre Dekker, Anna Rita Alitto, Maura Campitelli, Nicola Dinapoli, Roberto Gatta, Maria Antonietta Gambacorta, Vito Lanzotti, Philippe Lambin, Vincenzo Valentini
Future Oncology, 2016
ENT COBRA (Consortium for Brachytherapy Data Analysis): Interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy)
Luca Tagliaferri, György Kovács, Rosa Autorino, Ashwini Budrukkar, Jose Luis Guinot, Guido Hildebrand, Bengt Johansson, Rafael Martìnez Monge, Jens E. Meyer, Peter Niehoff, Angeles Rovirosa, Zoltàn Takàcsi-Nagy, Nicola Dinapoli, Vito Lanzotti, Andrea Damiani, Tamer Soror, Vincenzo Valentini
Journal of Contemporary Brachytherapy, 2016
Possible contribution of IMRT in postoperative radiochemotherapy for rectal cancer: Analysis on 1798 patients by prediction model
Wen-Yang Liu, Nicola Dinapoli, Xin Wang, Elisa Meldolesi, Maria Antonietta Gambacorta, Giuditta Chiloiro, Hua Ren, Hui Fang, Ning-Ning Lu, Yu Tang, Lei Deng, Jian-Yang Wang, Hao Jing, Qin Xiao, Yan-Ru Feng, Ye-Xiong Li, Shu-Lian Wang, Yong-Wen Song, Yue-Ping Liu, Wei-Hu Wang, Vincenzo Valentini, Jing Jin
Oncotarget, 2016
The Shape of Parotid DVH Predicts the Entity of Gland Deformation During IMRT for Head and Neck Cancers
S. Broggi, E. Scalco, C. Fiorino, M. L. Belli, G. Sanguineti, F. Ricchetti, I. Dell’Oca, N. Dinapoli, V. Valentini, N. Di Muzio, G. M. Cattaneo, G. Rizzo
Technology in Cancer Research and Treatment, 2015
Moddicom: A complete and easily accessible library for prognostic evaluations relying on image features
Nicola Dinapoli, Anna Rita Alitto, Mauro Vallati, Roberto Gatta, Rosa Autorino, Luca Boldrini, Andrea Damiani, Vincenzo Valentini
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBS, 2015
Adverse skin reactions during treatment with cetuximab plus radiotherapy: Multidisciplinary approach to minimize radio-chemotherapy interruption
Francesco Ricci, Andrea Paradisi, Sara Lanza Silveri, Francesca Sampogna, Francesco Miccichè, Pier L. Bonomo, Nicola DiNapoli, Vincenzo Valentini, Rodolfo Capizzi, Cristina Guerriero
Journal of Dermatological Treatment, 2015
Severe cholestatic hepatitis due to temozolomide: An adverse drug effect to keep in mind. Case report and review of literature
Antonio Grieco, Maria Antonietta Tafuri, Marco Biolato, Barbara Diletto, Nicola Di Napoli, Nicola Balducci, Fabio Maria Vecchio, Luca Miele
Medicine United States, 2015
Medicine is a science of uncertainty and an art of probability (Sir W. Osler)
Elisa Meldolesi, Johan van Soest, Nicola Dinapoli, Andre Dekker, Andrea Damiani, Maria Antonietta Gambacorta, Vincenzo Valentini
Radiotherapy and Oncology, 2015
Distributed learning to protect privacy in multi-centric clinical studies
Andrea Damiani, Mauro Vallati, Roberto Gatta, Nicola Dinapoli, Arthur Jochems, Timo Deist, Johan van Soest, Andre Dekker, Vincenzo Valentini
Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2015
Early changes of parotid density and volume predict modifications at the end of therapy and intensity of acute xerostomia
Maria Luisa Belli, Elisa Scalco, Giuseppe Sanguineti, Claudio Fiorino, Sara Broggi, Nicola Dinapoli, Francesco Ricchetti, Vincenzo Valentini, Giovanna Rizzo, Giovanni Mauro Cattaneo
Strahlentherapie Und Onkologie, 2014
Human papillomavirus (HPV) infection in squamous cell carcinomas arising from the oropharynx: Detection of HPV DNA and p16 immunohistochemistry as diagnostic and prognostic indicators - A pilot study
Francesco Bussu, Michela Sali, Roberto Gallus, Gianluigi Petrone, Gian Franco Zannoni, Rosa Autorino, Nicola Dinapoli, Rosaria Santangelo, Valerio Gaetano Vellone, Cristina Graziani, Francesco Miccichè, Giovanni Almadori, Jacopo Galli, Giovanni Delogu, Maurizio Sanguinetti, Guido Rindi, Massimo Tommasino, Vincenzo Valentini, Gaetano Paludetti
International Journal of Radiation Oncology Biology Physics, 2014
An umbrella protocol for standardized data collection (SDC) in rectal cancer: A prospective uniform naming and procedure convention to support personalized medicine
Elisa Meldolesi, Johan van Soest, Nicola Dinapoli, Andre Dekker, Andrea Damiani, Maria Antonietta Gambacorta, Vincenzo Valentini
Radiotherapy and Oncology, 2014
Clinical validation of atlas-based auto-segmentation of pelvic volumes and normal tissue in rectal tumors using auto-segmentation computed system
Maria Antonietta Gambacorta, Chiara Valentini, Nicola Dinapoli, Luca Boldrini, Nicola Caria, Maria Cristina Barba, Gian Carlo Mattiucci, Danilo Pasini, Bruce Minsky, Vincenzo Valentini
Acta Oncologica, 2013
HPV infection in squamous cell carcinomas arising from different mucosal sites of the head and neck region. Is p16 immunohistochemistry a reliable surrogate marker?
F Bussu, M Sali, R Gallus, V G Vellone, G F Zannoni, R Autorino, N Dinapoli, R Santangelo, R Martucci, C Graziani, F Miccichè, G Almadori, J Galli, G Delogu, M Sanguinetti, G Rindi, V Valentini, G Paludetti
British Journal of Cancer, 2013
The future of predictive models in radiation oncology: from extensive data mining to reliable modeling of the results
Vincenzo Valentini, Nicola Dinapoli, Andrea Damiani
Future Oncology, 2013
Recurrence in region of spared parotid gland in patient receiving definitive intensity-modulated radiotherapy for nasopharyngeal cancer: A case report
Rosa Autorino, Francesco Miccichè, Nicola Dinapoli, Francesco Bussu, Mario Balducci, Gian Carlo Mattiucci, Jacopo Galli, Tommaso Tartaglione, Vittoria Rufini, Giovanni Almadori, Gaetano Paludetti, Vincenzo Valentini
Acta Oncologica, 2012
Density variation of parotid glands during IMRT for head-neck cancer: Correlation with treatment and anatomical parameters
Claudio Fiorino, Giovanna Rizzo, Elisa Scalco, Sara Broggi, Maria Luisa Belli, Italo Dell’Oca, Nicola Dinapoli, Francesco Ricchetti, Aldo Mejia Rodriguez, Nadia Di Muzio, Riccardo Calandrino, Giuseppe Sanguineti, Vincenzo Valentini, Giovanni Mauro Cattaneo
Radiotherapy and Oncology, 2012
Nutritional counselling and oral nutritional supplements in head and neck cancer patients undergoing chemoradiotherapy
V. Valentini, F. Marazzi, M. Bossola, F. Miccichè, L. Nardone, M. Balducci, N. Dinapoli, P. Bonomo, R. Autorino, S. Silipigni, F. Giuliani, C. Tamanti, M. C. Mele, G. E. Martorana
Journal of Human Nutrition and Dietetics, 2012
Can "early" and "late" 18F-FDG PET-CT be used as prognostic factors for the clinical outcome of patients with locally advanced head and neck cancer treated with radio-chemotherapy?
Paola Castaldi, Vittoria Rufini, Francesco Bussu, Francesco Miccichè, Nicola Dinapoli, Rosa Autorino, Mariaelena Lago, Eugenio De Corso, Giovanni Almadori, Jacopo Galli, Gaetano Paludetti, Alessandro Giordano, Vincenzo Valentini
Radiotherapy and Oncology, 2012
Oncologic outcomes in advanced laryngeal squamous cell carcinomas treated with different modalities in a single institution: A retrospective analysis of 65 cases
Francesco Bussu, Francesco Miccichè, Mario Rigante, Nicola Dinapoli, Claudio Parrilla, Pierluigi Bonomo, Gabriella Cadoni, Giovanna Mantini, Jacopo Galli, Vittoria Rufini, Giovanni Almadori, Vincenzo Valentini, Gaetano Paludetti
Head and Neck, 2012
Erratum: The role of radiotherapy in adult medulloblastoma: Long-term single-institution experience and a review of the literature (J Neurooncol (2005) 64:10 (869-874) DOI 10.1007/s11060-011-0665-7)
M. Balducci, S. Chiesa, D. Chieffo, S. Manfrida, N. Dinapoli, A. Fiorentino, F. Miccichè, V. Frascino, C. Anile, V. Valentini, B. De Bari
Journal of Neuro Oncology, 2012
The role of radiotherapy in adult medulloblastoma: Long-term single-institution experience and a review of the literature
M. Balducci, S. Chiesa, D. Chieffo, S. Manfrida, N. Dinapoli, A. Fiorentino, F. Miccichè, V. Frascino, C. Anile, V. Valentini, B. De Bari
Journal of Neuro Oncology, 2012
Effect of whole pelvic radiotherapy for patients with locally advanced prostate cancer treated with radiotherapy and long-term androgen deprivation therapy
Giovanna Mantini, Luca Tagliaferri, Gian Carlo Mattiucci, Mario Balducci, Vincenzo Frascino, Nicola Dinapoli, Cinzia Di Gesù, Edy Ippolito, Alessio G. Morganti, Numa Cellini
International Journal of Radiation Oncology Biology Physics, 2011
Whole-brain radiotherapy combined with surgery or stereotactic radiotherapy in patients with brain oligometastases: Long-term analysis
Giuseppe Roberto D’Agostino, Rosa Autorino, Angelo Pompucci, Maria Carmen De Santis, Stefania Manfrida, Giuseppe Di Lella, Giovanna Mantini, Vincenzo Frascino, Silvia Chiesa, Alessio Albanese, Nicola Dinapoli, Luigi Azario, Alba Fiorentino, Vincenzo Valentini, Carmelo Anile, Mario Balducci
Strahlentherapie Und Onkologie, 2011
Multidisciplinary approach in the treatment of T1 glottic cancer: The role of patient preference in a homogenous patient population
Nicola Dinapoli, Claudio Parrilla, Jacopo Galli, Rosa Autorino, Francesco Miccichè, Francesco Bussu, Mario Balducci, Lucia D’Alatri, Raffaella Marchese, Mario Rigante, Giuseppe Di Lella, Luca Liberati, Giovanni Almadori, Gaetano Paludetti, Vincenzo Valentini
Strahlentherapie Und Onkologie, 2010
Single-arm phase ii study of conformal radiation therapy and temozolomide plus fractionated stereotactic conformal boost in high-grade gliomas: Final report
Mario Balducci, Giuseppina Apicella, Stefania Manfrida, Annunziato Mangiola, Alba Fiorentino, Luigi Azario, Giuseppe Roberto D’Agostino, Vincenzo Frascino, Nicola Dinapoli, Giovanna Mantini, Alessio Albanese, Pasquale de Bonis, Silvia Chiesa, Vincenzo Valentini, Carmelo Anile, Numa Cellini
Strahlentherapie Und Onkologie, 2010
Low-Dose Hyperradiosensitivity: Is There a Place for Future Investigation in Clinical Settings?
Vincenzo Valentini, Mariangela Massaccesi, Mario Balducci, Giovanna Mantini, Francesco Micciché, Gian Carlo Mattiucci, Nicola Dinapoli, Bruno Meduri, Giuseppe Roberto D'Agostino, Giovanna Salvi, Luigia Nardone
International Journal of Radiation Oncology Biology Physics, 2010
A two-variable linear model of parotid shrinkage during IMRT for head and neck cancer
Sara Broggi, Claudio Fiorino, Italo Dell’Oca, Nicola Dinapoli, Marta Paiusco, Alessandro Muraglia, Eleonora Maggiulli, Francesco Ricchetti, Vincenzo Valentini, Giuseppe Sanguineti, Giovanni Mauro Cattaneo, Nadia Di Muzio, Riccardo Calandrino
Radiotherapy and Oncology, 2010
Survival after radiotherapy in gastric cancer: Systematic review and meta-analysis
Vincenzo Valentini, Francesco Cellini, Bruce D. Minsky, Gian Carlo Mattiucci, Mario Balducci, Giuseppe D’Agostino, Elisa D’Angelo, Nicola Dinapoli, Nicola Nicolotti, Chiara Valentini, Giuseppe La Torre
Radiotherapy and Oncology, 2009
Videoconferencing to enhance the integration between clinical medicine and teaching: A feasibility study
Alessio G Morganti, Lino Pasquarelli, Francesco Deodato, Cinzia Digesù, Carlo Di Falco, Nicola Dinapoli, Gabriella Macchia, Vincenzo Picardi, Luca Tagliaferri, Vincenzo Valentini, Numa Cellini
Tumori, 2008
Application of a practical method for the isocenter point in vivo dosimetry by a transit signal
Angelo Piermattei, Andrea Fidanzio, Luigi Azario, Luca Grimaldi, Guido D'Onofrio, Savino Cilla, Gerardina Stimato, Diego Gaudino, Sara Ramella, Rolando D'Angelillo, Francesco Cellini, Lucio Trodella, Aniello Russo, Luciano Iadanza, Sergio Zucca, Vincenzo Fusco, Nicola Di Napoli, Maria Antonietta Gambacorta, Mario Balducci, Numa Cellini, Francesco Deodato, Gabriella Macchia, Alessio G Morganti
Physics in Medicine and Biology, 2007
In vivo dosimetry by an aSi-based EPID
Angelo Piermattei, Andrea Fidanzio, Gerardina Stimato, Luigi Azario, Luca Grimaldi, Guido D'Onofrio, Savino Cilla, Mario Balducci, Maria Antonietta Gambacorta, Nicola Di Napoli, Numa Cellini
Medical Physics, 2006
Impact of dose and volume on the tolerance of central nervous system
Rays International Journal of Radiological Sciences, 2005
Radiation-induced cardiovascular disease: Impact of dose and volume
Rays International Journal of Radiological Sciences, 2005
An application of visible human database in radiotherapy: Tutorial for image guided external radiotherapy (TIGER)
Vincenzo Valentini, Nicola Dinapoli, Stefania Nori, Gian Carlo Mattiucci, Giovanna Mantello, Laura Marucci, Maria Elena Rosetto, Numa Cellini
Radiotherapy and Oncology, 2004
Compensation for gaps in radiotherapy: suggested teaching approach to its calculation.
Rays, 2004
Clinical target volume definition in the elderly patient.
Rays, 2003
Underlying anatomy for CTV contouring and lymphatic drainage in rectal cancer radiation therapy.
Rays, 2003
Virtual simulation: fifteen years later.
Rays, 2003
Analysis of intraprostatic failures in patients treated with hormonal therapy and radiotherapy: Implications for conformal therapy planning
Numa Cellini, Alessio G Morganti, Gian C Mattiucci, Vincenzo Valentini, Mariavittoria Leone, Stefano Luzi, Riccardo Manfredi, Nicola Dinapoli, Cinzia Digesu’, Daniela Smaniotto
International Journal of Radiation Oncology Biology Physics, 2002

Nicola Dinapoli

RESEARCH INTERESTS

Scopus Publications

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