Pankaj Kishor Mishra

@subharti.org

Professor Department of Paramedical Sciences Subharti Medical College
Swami Vivekanand Subharti University Meerut



              

https://researchid.co/pkjbiotech

EDUCATION

PhD in Biochemistry

RESEARCH INTERESTS

Medical Biochemistry

21

Scopus Publications

1265

Scholar Citations

16

Scholar h-index

21

Scholar i10-index

Scopus Publications

  • The Influence of Greenery on Eye Health: A Botanical Perspective
    Khushi Kansal and Pankaj Kishor Mishra

    Diva Enterprises Private Limited

  • Determination of Metals and Metalloids in Traces in Honey by Inductively Coupled Plasma Mass Spectrometry
    Meenakshi Mishra, Pankaj Kishor Mishra, and Umesh Kumar

    Diva Enterprises Private Limited

  • Antimicrobial Activity of Aloe barbadensis (Aloe vera) Against Pathogenic Bacteria
    Anshu Kumar Singh, Shailesh Solanki, and Pankaj Kishor Mishra

    Diva Enterprises Private Limited

  • Constitutive expression and discovery of antimicrobial peptides in Zygogramma bicolorata (Coleoptera: Chrysomelidae)
    Vijaylakshmi Jain, Pankaj Kishor Mishra, Meenakshi Mishra, and Veeru Prakash

    Wiley
    The expression, identification, and discovery of less toxic antimicrobial peptides (AMPs) are significant in managing infectious pathogens. AMPs triggered in response to the immune system have evolved to defend against pathogens and wounding. The protein composition of Zygogramma bicolorata hemolymph is of diagnostic importance as the open circulatory systems of the insects involve signaling through hemolymph. They have conserved many ancestral vertebrate genes that may help better understand the evolution of innate immunity. The present work describes the isolation, purification, identification, and bioinformatics analysis of AMPs from the immunized hemolymph of Z. bicolorata. Thirty‐nine peptides were isolated from reverse‐phase high‐performance liquid chromatography and sequenced via mass spectrometry analysis. The immunization process recorded a threefold higher protein concentration in immunized hemolymph when compared with nonimmunized one. For the first time, the proteomic study on Z. bicolorata hemolymph unveils the three novel proteins in the family Chrysomelidae with no homology in the database, indicating its novelty and the expression of the rest of 36 well‐known proteins, including heat‐shock, immune, structural, signaling proteins, and others speak for its method validity. Combining the expression of novel AMPs, detoxifying enzymes, hemolytic, and cytotoxic assays, and this work can elucidate new pathways to immune response mechanisms. Its molecular basis also holds the potential applicability in the future drug development process against pathogenic fungi such as Aspergillus niger and Candida albicans.

  • Biogenic proceedings and characterization of copper-gold nanoalloy: Evaluation of their innate antimicrobial and catalytic activities
    Vijaylakshmi Jain, Azima Khusnud, Jaya Tiwari, Meenakshi Mishra, and Pankaj Kishor Mishra

    Informa UK Limited
    Abstract Crystallized polyhedral triangular-shaped Au-Cu nanoparticles (NPs) have been biosynthesized using the cell-free extract of the pathogenic fungal strain of Aspergillus niger. The bioreduction was monitored and characterized by UV-Visible spectroscopy, XRD, TEM, and NMR and confirmed the synthesized NPs to be crystallized polydispersed particles of 23–199 nm having FCC lattice. FTIR analysis predicted the amide region carbonyl group showed strong binding ability with metal, which acts as a capping agent and provides stability in the medium, efficient to inhibit various pathogenic bacteria and fungi at the minimum inhibitory concentration 0.0039 and 5 mg mL−1, respectively. On performing the bio-perspective analysis, the cytotoxicity assay detects a reduction in MTT levels, anticipating the normal functioning of the mitochondria and cell viability in comparison with controls and excellent significance of the catalytic activity, cell toxicity and reactive oxygen species production rate.

  • Phytochemicals: An approach towards antisickling activity


  • Phytochemical potency and biocompatible comparison of green and organic solvent


  • Antisickling and antioxidant relevance of twelve ethnomedicinal plants
    Pankaj Kishor Mishra, Shubhangi Sharma, Vijaylakshmi Jain, Jaya Tiwari, Meenakshi Mishra, P.K. Patra, and P.K. Khodiar

    Diva Enterprises Private Limited
    Sickle cell anaemia is the most devastating monogenic disease throughout the world carrying autosomal recessive inheritance. Easily accessible and affordable medicinal plants play the crucial role in the primary treatment of the disease. This study comprises of twelve such medicinal plants having secondary metabolites and their effect on the sickling reversal in vitro, with their antioxidant properties. The antisickling activity of aqueous extracts of plants was calculated at different concentrations (250, 500, 1000 μg/ml). Fifty sickled and fifty normal subjects were involved with their written consents. The spectrophotometrical analysis of antioxidants were determined enzymatically and non-enzymatically at different concentrations. All the plants were found capable of inhibiting RBC hemolysis and sickling but S8 (M. charantia) extract recorded prevention from the hemolysis and antisickling activity at 250 μg/ml and also possess antioxidants. Apart from S8 extract, S12 (S. bicolor), S2 (A. sativum) and S6 (C. sinensis) have also recorded higher antisickling activity and extracts of S2 (A.sativum), S3 (A. occidentale), S4 (C. papaya), S5 (C. cajan), S6 (C. sinensis), S7 (E. caryophyllata), S8 (M. charantia) and S9 (P. guajava) recorded strong antioxidant activities enzymatically and non-enzymatically, thus bestowed promising antioxidant and in vitro antisickling effects.

  • In vitro antioxidative and antifungal assessment of natural products against causative agents of otomycosis and candidiasis
    Jaya Tiwari, Vijaylakshmi Jain, Yashwant Kumar Ratre, Pankaj Kishor Mishra, and Pradeep Kumar Patra

    Diva Enterprises Private Limited

  • Polymorphism of CYP1A1 gene variants rs4646903 and rs1048943 relation to the incidence of cervical cancer in Chhattisgarh
    Vijaylakshmi Jain, Yashwant K. Ratre, Dnyanesh Amle, Pankaj K. Mishra, and Pradeep K. Patra

    Elsevier BV

  • Proteomic analysis in seeds of in vitro cultured Glycine max L. cv. merrill grown under cadmium stress


  • Phytochemical characterization of twelve medicinal plants used for sickle cell disease management in chhattisgarh


  • Metabolism of cisplatin in the organs of Rattus norvegicus: Role of Glutathione S-transferase P1
    Ritika Nagar, Amir Riyaz Khan, Anuj Poonia, Pankaj Kishor Mishra, and Simendra Singh

    Springer Science and Business Media LLC

  • 1-Cysteine peroxiredoxin: A less studied member of peroxiredoxin in plants


  • Diagnostic value of PCR in genitourinary tuberculosis
    Narotam Sharma, Veena Sharma, Prem Raj Singh, Shivani Sailwal, Rajeev S. Kushwaha, Rajesh K. Singh, Satish C. Nautiyal, Pankaj Mishra, Tariq Masood, and R. K. Singh

    Springer Science and Business Media LLC

  • Changes in antioxidant enzyme activities in Helianthus annuus L. under zinc-induced oxidative stress at different pH gradient


  • Age wise distribution of high risk human Papillomavirus in Northern Indian women


  • Cellular ion homeostasis mechanism in salt tolerant plants


  • Relevance of library and information technology resources in pharmaceutical research development in context of new digital era


  • Evaluation of biochemical response to zinc stress in cicer arietinum L


  • Screening of medicinal plant extracts for antioxidant activity


RECENT SCHOLAR PUBLICATIONS

  • Regulatory Disruptions in the Indian Telecommunication Industry
    P Mishra, NP Singh, A Farooq
    International Journal of Innovation and Technology Management, 2430007 2025

  • A review article on urinary tract infection among pregnant women’s
    AL Renthlei, Z Singh, Anshu Kumar, Naj, U Kumar, M Mishra, PK Mishra
    Indian Journal of Natural Sciences 15 (88), 87837-87843 2025

  • Impact of biochemical parameters on pregnancy: A comprehensive review
    Lalramdinpuii, U Kumar, M Mishra, A Kumar, AK Singh, PK Mishra
    European Journal of Biomedical and Pharmaceutical Sciences 12 (02), 152-156 2025

  • Pre-analytical errors during blood sample collection in Hematology Laboratory at CSSH
    A Kumar, C Rahul, Shivani, Lalremruati, U Kumar, KA Singh, PK Mishra
    Indian Journal of Natural Sciences 15 (88), 87593-87600 2025

  • A novel amalgamation of pre-processing technique and CNN model for accurate classification of power quality disturbances
    P Soni, P Mishra, D Mondal
    Electrical Engineering, 1-20 2024

  • An Enhanced Universal Soft Switching Dual Active Bridge Converter for Electric Vehicle Charging Infrastructure Towards Sustainable Electric Transportation
    SR Swain, SK Sarode, AS Lalitha, P Mishra, PP Kumar
    2024 IEEE 4th International Conference on Sustainable Energy and Future 2024

  • Distributed Voltage Unbalance Mitigation in Islanded Microgrid using Moth Flame Optimization and Firebug Swarm Optimization
    C Gandikoti, SK Jha, BM Jha, P Mishra
    International Journal of Power Electronics and Drive Systems (IJPEDS) 15 (2 2024

  • The nexus between allied policies of GST and FDI with dependent telecom policies of licensing and universal service in India
    P Mishra, NP Singh, A Farooq
    International Journal of Networking and Virtual Organisations 30 (2), 152-173 2024

  • Evaluation of antioxidant activities in methanolic stem bark extract of medicinal plants on rat liver treated with standard H2O2
    U Kumar, M Mishra, A Kumar, AK Singh, PK Mishra
    African Journal of Biomedical Research 27 (4), 8116-8120 2024

  • A case study on the cosmetic treatment through custom made prosthetic eye
    RK Manik, AK Singh, U Kumar, PK Mishra
    African Journal of Biomedical Research 27 (4), 8116-8120 2024

  • Analysis, Control and Simulation of Switched Boost Network Inverter using Modified PWM approach for E-bike Applications
    SS Kumar, GS Gupta, SK Mishra, P Mishra
    International Journal of Electrical Engineering and Computer Science 6, 176-183 2024

  • A Universal Soft Switching Dual Active Bridge Converter for Electric Vehicle Charging Infrastructure towards Sustainable Electric Transportation
    SS Kumar, AS Lalitha, GS Gupta, P Mishra, SK Mishra
    International Journal of Applied Sciences & Development 3 2024

  • Phytochemical and Antimicrobial Screening of Calotropis gigantean (Crown Flower) Leaves
    AK Singh, Z Naj, U Kumar, PK Mishra
    Indian Journal of Agricultural Biochemistry 37 (1), 66-70 2024

  • Measurement of skull size by using computed tomography for the development of bone conduction headset
    M Saini, VP Singh, PK Rajput, SK Yadav, A Kumar, Shmriti, A Singh, ...
    Indian Journal of Natural Sciences 15 (86), 81682-81689 2024

  • A study to determine gender variation of Maxillary Sinus dimensions by 3D CT in adult population of Western Uttar Pradesh region
    A Kala, SK Yadav, VP Singh, PK Rajput, Shmriti, A Kumar, PK Mishra
    Indian Journal of Natural Sciences 15 (86), 82229-82238 2024

  • Impact of Anemia in Development of Infants: A Review
    H Thakur, AK Tiwari, A Kumar, PK Mishra, U Kumar
    Acta Scientific Microbiology 7 (2), 79-85 2024

  • The impact of hospital acquired-infections on patient outcomes
    Z Naj, AK Singh, PK Mishra
    Asian Journal of Microbiology, Biotechnology & Environmental Sciences 26 (2 2024

  • A Cross-sectional study on Amblyopia Management
    RK Manik, K Kansal, U Kumar, PK Mishra
    Journal of Chemical Health Risks 14 (1), 2637-2645 2024

  • The effects of Protein-Energy Malnutrition on Children under five years of age
    M Zubair, M Mishra, U Kumar, PK Mishra
    International Journal of Pharma and Biosciences 15 (1), b39-53 2024

  • A review on sources identification of heavy metals in soil and remediation measures by phytoremediation-induced methods
    S Madhav, R Mishra, A Kumari, AL Srivastav, A Ahamad, P Singh, ...
    International Journal of Environmental Science and Technology 21 (1), 1099-1120 2024

MOST CITED SCHOLAR PUBLICATIONS

  • Screening of medicinal plant extracts for antioxidant activity
    P Veeru, MP Kishor, M Meenakshi
    Journal of Medicinal Plants Research 3 (8), 608-612 2009
    Citations: 230

  • Stevia rebaudiana–A magical sweetener
    P Mishra, R Singh, U Kumar, V Prakash
    Global Journal of Biotecnology & Biochemistry 5 (1), 62-74 2010
    Citations: 164

  • Efficiency of plant growth promoting rhizobacteria for the enhancement of Cicer arietinum L. growth and germination under salinity
    M Mishra, U Kumar, PK Mishra, V Prakash
    Adv Biol Res 4 (2), 92-96 2010
    Citations: 149

  • Antidiabetic and hypolipidemic activity of Gymnema sylvestre in alloxan induced diabetic rats
    GK Mall, PK Mishra, V Prakash
    Global Journal of Biotechnology & Biochemistry 4 (1), 37-42 2009
    Citations: 133

  • A review on sources identification of heavy metals in soil and remediation measures by phytoremediation-induced methods
    S Madhav, R Mishra, A Kumari, AL Srivastav, A Ahamad, P Singh, ...
    International Journal of Environmental Science and Technology 21 (1), 1099-1120 2024
    Citations: 60

  • Response of iodine on antioxidant levels of Glycine max L. grown under Cd2+ stress
    N Gupta, M Bajpai, R Majumdar, P Mishra
    Adv Biol Res 9 (1), 40-48 2015
    Citations: 59

  • NaCl phytotoxicity induces oxidative stress and response of antioxidant systems in Cicer arietinum L. cv. Abrodhi
    M Mishra, PK Mishra, U Kumar, V Prakash
    Botany Research International 2 (2), 74-82 2009
    Citations: 39

  • Characterization of a magnetorheological fluid damper a review
    PN Vishwakarma, P Mishra, SK Sharma
    Materials Today: Proceedings 56, 2988-2994 2022
    Citations: 38

  • A neural network for image anomaly detection with deep pyramidal representations and dynamic routing
    P Mishra, C Piciarelli, GL Foresti
    International Journal of Neural Systems 30 (10), 2050060 2020
    Citations: 34

  • Polymorphism of CYP1A1 gene variants rs4646903 and rs1048943 relation to the incidence of cervical cancer in Chhattisgarh
    V Jain, YK Ratre, D Amle, PK Mishra, PK Patra
    Environmental toxicology and pharmacology 52, 188-192 2017
    Citations: 31

  • Metabolism of cisplatin in the organs of Rattus norvegicus: role of Glutathione S-transferase P1
    R Nagar, AR Khan, A Poonia, PK Mishra, S Singh
    European Journal of Drug Metabolism and Pharmacokinetics 40, 45-51 2015
    Citations: 21

  • Comparative hypoglycemic effects of different extract of Clitoria ternatea leaves on rats
    S Abhishek, S Vikas, K Minu, M Pankaj
    IOSR Journal of Pharmacy and Biological Sciences 10, 60-65 2015
    Citations: 21

  • Some fresh water algae of eastern Uttar Pradesh, India
    PK Misra, AK Srivastava, J Prakash, DK Asthana, SK Rai
    Our Nature 3 (1), 77-80 2005
    Citations: 19

  • Response of non-enzymatic antioxidants to zinc Induced stress at different pH in Glycine max L. cv. Merrill
    PK Mishra, V Prakash
    Academic Journal of Plant Sciences 3 (1), 1-10 2010
    Citations: 18

  • Synthesis and evaluation of anti-inflammatory activity of some cinnoline derivatives-4 (-2-amino-thiophene) cinnoline-3-carboxamide
    P Mishra, A Middha, V Saxena, A Saxena
    Pharmaceutical and Biosciences Journal, 64-68 2016
    Citations: 16

  • Hypoglycemic effects of Clitoria ternatea leaves (Linn) Extract
    S Abhishek, M Pankaj, S Vikas
    Journal of Pharmacology and Toxicological Studies 1 (1), 4-7 2013
    Citations: 16

  • Method and system for generating a signal strength map
    AK Singh, P Mishra
    US Patent 10,327,110 2019
    Citations: 14

  • Image anomaly detection by aggregating deep pyramidal representations
    P Mishra, C Piciarelli, GL Foresti
    International Conference on Pattern Recognition, 705-718 2021
    Citations: 13

  • Synthesis, characterization and antiinflammatory activity of cinnolines (pyrazole) derivatives
    P Mishra, V Saxena, K Minu, S Abhishek
    IOSR J Pharm Biol Sci 10 (6), 77-82 2015
    Citations: 13

  • Synthesis, characterization and pharmacological evaluation of cinnoline (thiophene) derivatives
    M Pankaj, S Vikas, K Minu, S Abhishek
    The Pharma Innovation 4 (10, Part B), 68 2015
    Citations: 12