Pankaj Kishor Mishra

@subharti.org

Professor Department of Paramedical Sciences Subharti Medical College
Swami Vivekanand Subharti University Meerut

Pankaj Kishor Mishra


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https://researchid.co/pkjbiotech

EDUCATION

PhD in Biochemistry

RESEARCH INTERESTS

Medical Biochemistry
25

Scopus Publications

1655

Scholar Citations

17

Scholar h-index

26

Scholar i10-index

Scopus Publications

  • Structured role of C-reactive protein (CRP) in clinical diagnostic and prognostic medicine
    Muhammad Zubair, Pankaj Kishor Mishra, Saurabh Singhal
    Chemical Biology Letters, 2025
    C-reactive protein (CRP) is a widely used biomarker for inflammation, infection, and various disease states. This review explores the role of CRP in the diagnosis and prognosis of several conditions, including autoimmune diseases, cardiovascular diseases (CVD), chronic kidney disease (CKD), cancer, COVID-19, periodontitis, cirrhosis, and hypertension. CRP levels are elevated in many of these conditions, making it a useful tool for monitoring disease progression. In autoimmune diseases like rheumatoid arthritis, CRP is associated with disease activity and severity. For CVD, high-sensitivity CRP (hs-CRP) is a valuable predictor of cardiovascular events and is included in risk calculators. CRP also plays a role in the pathogenesis of acute kidney injury and CKD, with higher levels linked to worse outcomes. In cancer, elevated CRP is associated with increased risk for various types of malignancies. During the COVID-19 pandemic, CRP levels correlated with disease severity and mortality. Periodontitis, cirrhosis, and hypertension have also been linked to increased CRP levels, although the association with hypertension remains controversial. The review also discusses the biological functions of CRP, its role in saliva, and the importance of systematic reviews and meta-analyses in evaluating CRP measurement approaches and diagnostic accuracy. Furthermore, the article highlights recent advances in CRP detection methods, emerging biomarkers studied alongside CRP, and the application of CRP in precision medicine. While CRP is a valuable biomarker, its utility for distinguishing between inflammatory and non-inflammatory conditions can be limited, and it is often used in conjunction with other markers to improve diagnostic accuracy.
  • Determination of Mineral Contents and Heavy Metals of Oats Samples by Inductively Coupled Plasma Mass Spectrometry
    Meenakshi Mishra, Pankaj Kishor Mishra, Umesh Kumar
    Indian Journal of Agricultural Biochemistry, 2025
    Products made from oats, such as probiotic drinks, breads, biscuits, cookies and instant muesli (rolled oats), are becoming more and more popular. The number of heavy metals present in rolled oats has not been reported. This study sets out to ascertain the Lead (Pb) and Copper (Cu) contents in rolled oats that were collected from various parts of India, as well as to evaluate the safety of the rolled oats that were sold in India’s domestic market for human consumption. Oats have anticancer properties and are useful for gastrointestinal issues. One kind of minimally processed wholegrain food is rolled oats. Traditionally, they are manufactured from steamed and dehusked oat groats which are then rolled into flat flakes by heavy rollers and lightly roasted to stabilise. The rough outer bran of rolled oats is typically removed before being sold for porridge. They have frequently-though not always-been pressure-cooked, softly baked, or subjected to various types of processing. Large intact flakes are known as thick-rolled oats, whereas tiny, fragmented flakes are known as thin-rolled oats. Five samples were analysed in the lab; four of them were collected with FSSAI MRL values below the maximum residue level and the fifth sample had MRL values over the maximum. The FSSAI limit “Food not specified” yields the MRL value. With measurements of Pb-0.0344, Cu-3.7922, As-0.0081, Cd-0.0034, Sn-0.0036, Hg-0.0190, and the poorest sample, Pb-0.312, Cu-30.26, As-2.00, Cd-251, Sn-1.523, and Hg-2.88, Oats’ second sample yielded the best results.
  • Phytochemical and Antimicrobial Screening of Calotropis gigantean (Crown Flower) Leaves
    Anshu Kumar Singh, Zeba Naj, Umesh Kumar, Pankaj Kishor Mishra
    Indian Journal of Agricultural Biochemistry, 2024
  • The Influence of Greenery on Eye Health: A Botanical Perspective
    Khushi Kansal, Pankaj Kishor Mishra
    Indian Journal of Agricultural Biochemistry, 2023
  • Determination of Metals and Metalloids in Traces in Honey by Inductively Coupled Plasma Mass Spectrometry
    Meenakshi Mishra, Pankaj Kishor Mishra, Umesh Kumar
    Indian Journal of Agricultural Biochemistry, 2023
  • Antimicrobial Activity of Aloe barbadensis (Aloe vera) Against Pathogenic Bacteria
    Anshu Kumar Singh, Shailesh Solanki, Pankaj Kishor Mishra
    Indian Journal of Agricultural Biochemistry, 2023
  • Constitutive expression and discovery of antimicrobial peptides in Zygogramma bicolorata (Coleoptera: Chrysomelidae)
    Vijaylakshmi Jain, Pankaj Kishor Mishra, Meenakshi Mishra, Veeru Prakash
    Proteins Structure Function and Bioinformatics, 2022
    The expression, identification, and discovery of less toxic antimicrobial peptides (AMPs) are significant in managing infectious pathogens. AMPs triggered in response to the immune system have evolved to defend against pathogens and wounding. The protein composition of Zygogramma bicolorata hemolymph is of diagnostic importance as the open circulatory systems of the insects involve signaling through hemolymph. They have conserved many ancestral vertebrate genes that may help better understand the evolution of innate immunity. The present work describes the isolation, purification, identification, and bioinformatics analysis of AMPs from the immunized hemolymph of Z. bicolorata. Thirty‐nine peptides were isolated from reverse‐phase high‐performance liquid chromatography and sequenced via mass spectrometry analysis. The immunization process recorded a threefold higher protein concentration in immunized hemolymph when compared with nonimmunized one. For the first time, the proteomic study on Z. bicolorata hemolymph unveils the three novel proteins in the family Chrysomelidae with no homology in the database, indicating its novelty and the expression of the rest of 36 well‐known proteins, including heat‐shock, immune, structural, signaling proteins, and others speak for its method validity. Combining the expression of novel AMPs, detoxifying enzymes, hemolytic, and cytotoxic assays, and this work can elucidate new pathways to immune response mechanisms. Its molecular basis also holds the potential applicability in the future drug development process against pathogenic fungi such as Aspergillus niger and Candida albicans.
  • Biogenic proceedings and characterization of copper-gold nanoalloy: Evaluation of their innate antimicrobial and catalytic activities
    Vijaylakshmi Jain, Azima Khusnud, Jaya Tiwari, Meenakshi Mishra, Pankaj Kishor Mishra
    Inorganic and Nano Metal Chemistry, 2021
    Crystallized polyhedral triangular-shaped Au-Cu nanoparticles (NPs) have been biosynthesized using the cell-free extract of the pathogenic fungal strain of Aspergillus niger. The bioreduction was monitored and characterized by UV-Visible spectroscopy, XRD, TEM, and NMR and confirmed the synthesized NPs to be crystallized polydispersed particles of 23–199 nm having FCC lattice. FTIR analysis predicted the amide region carbonyl group showed strong binding ability with metal, which acts as a capping agent and provides stability in the medium, efficient to inhibit various pathogenic bacteria and fungi at the minimum inhibitory concentration 0.0039 and 5 mg mL−1, respectively. On performing the bio-perspective analysis, the cytotoxicity assay detects a reduction in MTT levels, anticipating the normal functioning of the mitochondria and cell viability in comparison with controls and excellent significance of the catalytic activity, cell toxicity and reactive oxygen species production rate.
  • Phytochemicals: An approach towards antisickling activity
    A Comprehensive Guide to Natural Products, 2020
  • Phytochemical potency and biocompatible comparison of green and organic solvent
    A Comprehensive Guide to Natural Products, 2020
  • Antisickling and antioxidant relevance of twelve ethnomedicinal plants
    Pankaj Kishor Mishra, Shubhangi Sharma, Vijaylakshmi Jain, Jaya Tiwari, Meenakshi Mishra, et al.
    Medicinal Plants, 2018
  • In vitro antioxidative and antifungal assessment of natural products against causative agents of otomycosis and candidiasis
    Jaya Tiwari, Vijaylakshmi Jain, Yashwant Kumar Ratre, Pankaj Kishor Mishra, Pradeep Kumar Patra
    Indian Journal of Agricultural Biochemistry, 2018
  • Polymorphism of CYP1A1 gene variants rs4646903 and rs1048943 relation to the incidence of cervical cancer in Chhattisgarh
    Vijaylakshmi Jain, Yashwant K. Ratre, Dnyanesh Amle, Pankaj K. Mishra, Pradeep K. Patra
    Environmental Toxicology and Pharmacology, 2017
  • Proteomic analysis in seeds of in vitro cultured Glycine max L. cv. merrill grown under cadmium stress
    Indian Journal of Agricultural Biochemistry, 2015
  • Metabolism of cisplatin in the organs of Rattus norvegicus: Role of Glutathione S-transferase P1
    Ritika Nagar, Amir Riyaz Khan, Anuj Poonia, Pankaj Kishor Mishra, Simendra Singh
    European Journal of Drug Metabolism and Pharmacokinetics, 2015
  • Phytochemical characterization of twelve medicinal plants used for sickle cell disease management in chhattisgarh
    International Journal of Pharma and Bio Sciences, 2015
  • 1-Cysteine peroxiredoxin: A less studied member of peroxiredoxin in plants
    International Journal of Pharma and Bio Sciences, 2013
  • Diagnostic value of PCR in genitourinary tuberculosis
    Narotam Sharma, Veena Sharma, Prem Raj Singh, Shivani Sailwal, Rajeev S. Kushwaha, et al.
    Indian Journal of Clinical Biochemistry, 2013
  • Changes in antioxidant enzyme activities in Helianthus annuus L. under zinc-induced oxidative stress at different pH gradient
    Indian Journal of Agricultural Biochemistry, 2013
  • Age wise distribution of high risk human Papillomavirus in Northern Indian women
    Biomedical Research India, 2012
  • Cellular ion homeostasis mechanism in salt tolerant plants
    Indian Journal of Agricultural Biochemistry, 2011
  • Relevance of library and information technology resources in pharmaceutical research development in context of new digital era
    International Journal of Pharmacy and Pharmaceutical Sciences, 2010
  • Screening of medicinal plant extracts for antioxidant activity
    Journal of Medicinal Plants Research, 2009
  • Evaluation of biochemical response to zinc stress in cicer arietinum L
    Indian Journal of Agricultural Biochemistry, 2009
  • A study on distribution of permanent methods of contraception acceptors by select variables
    Health and Population Perspectives and Issues, 2009

RECENT SCHOLAR PUBLICATIONS

  • Nanotoxicity and risk assessment of nanomedicine
    VP Singh, PK Rajput, M Mishra, U Kumar, PK Mishra
    Nanomedicine 1, 204-216 , 2026
    2026
  • Blood Donar and Deferrals and their Underlying Reasons at a Tertiary Care Hospital: A Retrospective Study
    A Tyagi, A Kumar, U Kumar, M Mishra, PK Mishra
    Indian Journal of Natural Sciences 16 (94), 106675-106683 , 2026
    2026
  • Structured role of C-reactive protein (CRP) in clinical diagnostic and prognostic medicine
    M Zubair, PK Mishra, S Singhal
    Chemical Biology Letters 12 (4), 1280 , 2025
    2025
  • Optimized neural network for soil moisture prediction in precision agriculture
    P Soni, R Kumar, S Mishra, S Swain, P Mishra, SS Kumar
    Measurement 252, 117380 , 2025
    2025
    Citations: 5
  • Optimal placement of charging stations based on the charge scheduling optimization
    SK Jha, SK Jha, P Mishra, BM Jha
    Intelligent Decision Technologies 19 (4), 2099-2122 , 2025
    2025
  • A novel amalgamation of pre-processing technique and CNN model for accurate classification of power quality disturbances
    P Soni, P Mishra, D Mondal
    Electrical Engineering 107 (4), 5187-5206 , 2025
    2025
    Citations: 3
  • Signature of localization–delocalization in collisional inhomogeneous spin-orbit coupled condensates
    SK Sarkar, R Ravisankar, T Mishra, P Muruganandam, P Mishra
    Journal of Physics B: Atomic, Molecular and Optical Physics 58 (6), 065001 , 2025
    2025
    Citations: 2
  • Mitigating low inertia challenges in renewable energy-based microgrids: A survey
    M Kumar, DS Acharya, P Mishra
    2025 IEEE 1st International Conference on Smart and Sustainable Developments … , 2025
    2025
    Citations: 2
  • Effect of Different Management Practices on Yield Attributes and Productivity of Wheat+ Mustard Intercropping System
    R Kumbhare, PK Mishra, R Sahu, V Gupta, R Patel, K Singh
    International Journal of Plant & Soil Science 37 (1), 550-563 , 2025
    2025
  • Review on the use of Polymerase Chain Reaction in antimicrobial resistance detection in clinical microbiology
    GT Mapere, AK Singh, N Singh, PK Mishra
    Indian Journal of Natural Sciences 16 (91), 98206-98218 , 2025
    2025
  • Determination of mineral contents and heavy metals of oats samples by inductively coupled Plasma Mass Spectrometry
    M Mishra, PK Mishra, U Kumar
    Indian Journal of Agricultural Biochemistry 38 (1), 27-30 , 2025
    2025
  • Review on abnormal antibody development and identification in blood transfused recipients
    A Tyagi, A Kumar, U Kumar, PK Mishra, D Swarup
    Indian Journal of Natural Sciences 16 (90), 94529-94538 , 2025
    2025
  • A study on urinary tract infections among adults in Western Uttar Pradesh
    AL Renthlei, Z Singh, Anshu Kumar, Naj, U Kumar, M Mishra, PK Mishra
    Indian Journal of Natural Sciences 16 (89), 90949-90957 , 2025
    2025
  • A review article on urinary tract infection among pregnant women’s
    AL Renthlei, Z Singh, Anshu Kumar, Naj, U Kumar, M Mishra, PK Mishra
    Indian Journal of Natural Sciences 15 (88), 87837-87843 , 2025
    2025
  • Impact of biochemical parameters on pregnancy: A comprehensive review
    Lalramdinpuii, U Kumar, M Mishra, A Kumar, AK Singh, PK Mishra
    European Journal of Biomedical and Pharmaceutical Sciences 12 (02), 152-156 , 2025
    2025
    Citations: 1
  • Pre-analytical errors during blood sample collection in Hematology Laboratory at CSSH
    A Kumar, C Rahul, Shivani, Lalremruati, U Kumar, KA Singh, PK Mishra
    Indian Journal of Natural Sciences 15 (88), 87593-87600 , 2025
    2025
  • Regulatory Disruptions in the Indian Telecommunication Industry
    P Mishra, NP Singh, A Farooq
    International Journal of Innovation and Technology Management 21 (08), 2430007 , 2024
    2024
  • An Enhanced Universal Soft Switching Dual Active Bridge Converter for Electric Vehicle Charging Infrastructure Towards Sustainable Electric Transportation
    SR Swain, SK Sarode, AS Lalitha, P Mishra, PP Kumar
    2024 IEEE 4th International Conference on Sustainable Energy and Future … , 2024
    2024
  • Distributed voltage unbalance mitigation in islanded microgrid using moth flame optimization and firebug swarm optimization
    C Gandikoti, SK Jha, BM Jha, P Mishra
    International Journal of Power Electronics and Drive Systems (IJPEDS) 15 (2 … , 2024
    2024
    Citations: 4
  • ASIAN JOURNAL OF MICROBIOLOGY, BIOTECHNOLOGY AND ENVIRONMENTAL SCIENCES VOL. 26 (2): 2024
    H PALANI, R PALANI, P KUMAR, R VISWAKARMA, DM DEVI, ...
    ENVIRONMENTAL SCIENCES 26, 2 , 2024
    2024

MOST CITED SCHOLAR PUBLICATIONS

  • Screening of medicinal plant extracts for antioxidant activity
    P Veeru, MP Kishor, M Meenakshi
    Journal of Medicinal Plants Research 3 (8), 608-612 , 2009
    2009
    Citations: 243
  • Stevia rebaudiana–A magical sweetener
    P Mishra, R Singh, U Kumar, V Prakash
    Global Journal of Biotecnology & Biochemistry 5 (1), 62-74 , 2010
    2010
    Citations: 182
  • Efficiency of plant growth promoting rhizobacteria for the enhancement of Cicer arietinum L. growth and germination under salinity
    M Mishra, U Kumar, PK Mishra, V Prakash
    Adv Biol Res 4 (2), 92-96 , 2010
    2010
    Citations: 179
  • Antidiabetic and hypolipidemic activity of Gymnema sylvestre in alloxan induced diabetic rats
    GK Mall, PK Mishra, V Prakash
    Global Journal of Biotechnology & Biochemistry 4 (1), 37-42 , 2009
    2009
    Citations: 144
  • A review on sources identification of heavy metals in soil and remediation measures by phytoremediation-induced methods
    S Madhav, R Mishra, A Kumari, AL Srivastav, A Ahamad, P Singh, ...
    International Journal of Environmental Science and Technology 21 (1), 1099-1120 , 2024
    2024
    Citations: 124
  • Characterization of a magnetorheological fluid damper a review
    PN Vishwakarma, P Mishra, SK Sharma
    Materials Today: Proceedings 56, 2988-2994 , 2022
    2022
    Citations: 65
  • Response of iodine on antioxidant levels of Glycine max L. grown under Cd2+ stress
    N Gupta, M Bajpai, R Majumdar, P Mishra
    Advances in Biological Research 9 (1), 40-48 , 2015
    2015
    Citations: 61
  • Emergence of periwinkle Catharanthus roseus as a model system for molecular biology of alkaloids: phytochemistry, pharmacology, plant biology and in vivo and in vitro cultivation
    P Mishra, S Kumar
    Journal of Medicinal and Aromatic Plant Sciences 22 (2/3), 306 , 2000
    2000
    Citations: 45
  • NaCl phytotoxicity induces oxidative stress and response of antioxidant systems in Cicer arietinum L. cv. Abrodhi
    M Mishra, PK Mishra, U Kumar, V Prakash
    Botany Research International 2 (2), 74-82 , 2009
    2009
    Citations: 41
  • Variability in fruit characters of chilli ( Capsicum annuum L.).
    A Mishra, GS Sahu, PK Mishra
    2001
    Citations: 40
  • A neural network for image anomaly detection with deep pyramidal representations and dynamic routing
    P Mishra, C Piciarelli, GL Foresti
    International Journal of Neural Systems 30 (10), 2050060 , 2020
    2020
    Citations: 37
  • Polymorphism of CYP1A1 gene variants rs4646903 and rs1048943 relation to the incidence of cervical cancer in Chhattisgarh
    V Jain, YK Ratre, D Amle, PK Mishra, PK Patra
    Environmental toxicology and pharmacology 52, 188-192 , 2017
    2017
    Citations: 35
  • Metabolism of cisplatin in the organs of Rattus norvegicus : role of Glutathione S -transferase P1
    R Nagar, AR Khan, A Poonia, PK Mishra, S Singh
    European Journal of Drug Metabolism and Pharmacokinetics 40 (1), 45-51 , 2015
    2015
    Citations: 23
  • Comparative hypoglycemic effects of different extract of Clitoria ternatea leaves on rats
    S Abhishek, S Vikas, K Minu, M Pankaj
    IOSR Journal of Pharmacy and Biological Sciences 10, 60-65 , 2015
    2015
    Citations: 23
  • Some fresh water algae of eastern Uttar Pradesh, India
    PK Misra, AK Srivastava, J Prakash, DK Asthana, SK Rai
    Our Nature 3 (1), 77-80 , 2005
    2005
    Citations: 20
  • Synthesis and evaluation of anti-inflammatory activity of some cinnoline derivatives-4 (-2-amino-thiophene) cinnoline-3-carboxamide
    P Mishra, A Middha, V Saxena, A Saxena
    Pharmaceutical and Biosciences Journal, 64-68 , 2016
    2016
    Citations: 19
  • Hypoglycemic effects of Clitoria ternatea leaves (Linn) Extract
    S Abhishek, M Pankaj, S Vikas
    Journal of Pharmacology and Toxicological Studies 1 (1), 4-7 , 2013
    2013
    Citations: 19
  • Image anomaly detection by aggregating deep pyramidal representations
    P Mishra, C Piciarelli, GL Foresti
    International Conference on Pattern Recognition, 705-718 , 2021
    2021
    Citations: 17
  • Response of non-enzymatic antioxidants to zinc Induced stress at different pH in Glycine max L. cv. Merrill
    PK Mishra, V Prakash
    Academic Journal of Plant Sciences 3 (1), 1-10 , 2010
    2010
    Citations: 17
  • Synthesis, Characterization and Antiinflammatory activity of Cinnolines (pyrazole) derivatives
    P Mishra, V Saxena, M Kesheri, A Saxena
    IOSR J Pharm Biol Sci 10 (6), 77-82 , 2015
    2015
    Citations: 15