D. MUNIRAJASEKHAR

@sietk.org

Head of the Department, Department of Chemistry
Siddharth Institute of Engineering and Technology

D. MUNIRAJASEKHAR


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https://researchid.co/chemmuni

EDUCATION

M.Sc (Organic chemistry), Ph. D (Organic chemistry)

RESEARCH, TEACHING, or OTHER INTERESTS

Organic Chemistry, General Chemistry, Inorganic Chemistry

FUTURE PROJECTS

Synthesis of Novel Organic Molecules


Applications Invited

Peptide chemistry


Applications Invited

Corrosion studies


Applications Invited
17

Scopus Publications

209

Scholar Citations

8

Scholar h-index

5

Scholar i10-index

Scopus Publications

  • MOLECULAR MECHANISMS OF MICROBIAL RESISTANCE: IMPLICATIONS FOR BIOTECHNOLOGY AND DRUG DEVELOPMENT
    Genetics and Molecular Research, 2026
  • G3XMP2 investigation of amine inversion in aniline and its para anilines
    Asian Journal of Pharmaceutical and Clinical Research, 2014
  • Insecticidal activity of substituted 1,3-diynes
    Journal of Chemical and Pharmaceutical Research, 2014
  • Development and validation of a headspace gas chromatographic method for the determination of ethyl alcohol in ketorolac tromethamine injection
    Journal of Chemical and Pharmaceutical Research, 2014
  • A facile and efficient synthesis of 2-(5-(4-substitutedphenyl)-4, 5-dihydro-3-phenylpyrazol-1-yl)-6-substitutedbenzothiazoles and their biological studies
    D. Munirajasekhar, M. Himaja, Sunil V. Mali
    Journal of Heterocyclic Chemistry, 2014
    A series of new 1‐substituted 3, 5‐diarylpyrazolines (10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25) were synthesized in good yield by both conventional and microwave‐assisted synthesis from α, β‐ unsaturated ketones (6, 7, 8, 9) in n‐butanol and benzothiazole hydrazines (2, 3, 4, 5). All the new compounds were characterized by IR, NMR, and mass spectral data. The synthesized compounds (10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25) were evaluated for antibacterial and anthelmintic activities. The compounds showed potent anthelmintic activity against earthworm species (Eudrilus eugeniae) and moderate antibacterial activity against bacterial strains such as Gram positive bacteria, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis, and Gram negative bacteria, Escherichia coli and Proteus mirabilis.
  • Synthesis of new (Pyrazol-3-yl)-1,3,4-oxadiazole derivatives by unexpected aromatization during oxidative cyclization of 4,5-dihydro-1h-pyrazole-3- carbohydrazones and their biological activities
    K. Jagadeesh Prathap, M. Himaja, Sunil V. Mali, D. Munirajasekhar
    Journal of Heterocyclic Chemistry, 2014
    A series of novel 2‐(4‐(4‐chlorophenyl)‐1H‐pyrazol‐3‐yl)‐5‐(Aryl)‐1,3,4‐oxadiazoles were synthesized by unexpected aromatization during oxidative cyclization of 4‐(4‐chlorophenyl)‐4,5‐dihydro‐1H‐pyrazole‐3‐carbohydrazones using chloramine‐T as an oxidant. The hydrazones were derived from 4‐(4‐chlorophenyl)‐4,5‐dihydro‐1H‐pyrazole‐3‐carbohydrazide and various substituted aldehydes. The structure of the synthesized compounds was confirmed by FTIR, 1H NMR, 13C NMR, and mass spectral data. The synthesized compounds were evaluated for their antitubercular and antioxidant activities. All the compounds 4a, 4b, 4c, 4d, 4e, 4f, 4g, 4h and 5a, 5b, 5c, 5d, 5e, 5f, 5g, 5h showed good antitubercular activity against Mycobacterium tuberculosis (minimum inhibitory concentration = 25 µg/mL for 4f and 4g, 50–100 µg/mL for the rest). However, all the compounds exhibited poor antioxidant activity against 1,1‐diphenyl‐2‐picryl‐hydrazil free radical.
  • Copper (I) assisted catalyst synthesis of substituted allenes and their biological studies
    International Journal of Research in Pharmaceutical Sciences, 2014
  • Synthesis, docking and biological studies of the linear tetrapeptide PWPV-A potent insecticidal agent
    International Journal of Pharmacy and Pharmaceutical Sciences, 2013
  • 1-(6-Fluoro-1,3-benzothia-zol-2-yl)-2-(1-phenyl-ethyl-idene)hydrazine
    Hoong-Kun Fun, Ching Kheng Quah, D. Munirajasekhar, M. Himaja, B. K. Sarojini
    Acta Crystallographica Section E Structure Reports Online, 2012
    The asymmetric unit of the title compound, C15H12FN3S, consists of two independent molecules with comparable geometries. In one molecule, the 1,3-benzothiazole ring system (r.m.s. deviation = 0.011 Å) forms a dihedral angle of 19.86 (6)° with the phenyl ring. The corresponding r.m.s. deviation and dihedral angle for the other molecule are 0.014 Å and 22.32 (6)°, respectively. In the crystal, molecules are linkedviaN—H...N, C—H...F and C—H...N hydrogen bonds into a three-dimensional network. The crystal studied was a non-merohedral twin with a refined BASF value of 0.301 (2).
  • Synthesis of glabrin a and its N-methylated analog as potent insecticidal agents
    International Journal of Research in Ayurveda and Pharmacy, 2012
  • Synthesis of novel azetidinone derivatives as antitubercular agents
    M. Himaja, Asif Karigar, M. V. Ramana, D. Munirajasekhar, Mukesh S. Sikarwar
    Letters in Drug Design and Discovery, 2012
  • Synthesis and evaluation of antitubercular activity of some lamivudine based hybrid drugs
    International Journal of Research in Ayurveda and Pharmacy, 2012
  • Synthesis, anthelmintic, insecticidal activity of (E)-1-((1-(6- chlorobenzo[d]thiazol-2-yl)-3-phenyl-1H-pyrazol-4-yl)methylene) -2-(6-substituted benzo[d]thiazol-2-yl)hydrazine derivatives
    Asian Journal of Chemistry, 2012
  • Synthesis, docking and antioxidant activity of some NSAID derivatives of amines
    International Journal of Research in Ayurveda and Pharmacy, 2012
  • 1-(6-Fluoro-1,3-benzothiazol-2-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde
    Hoong-Kun Fun, Chin Wei Ooi, D. Munirajasekhar, M. Himaja, B. K. Sarojini
    Acta Crystallographica Section E Structure Reports Online, 2011
  • 7-Chloro-3-phenylbenzo[4,5]thiazolo[2,3-c][1,2,4]triazole
    Hoong-Kun Fun, Safra Izuani Jama Asik, M. Himaja, D. Munirajasekhar, B. K. Sarojini
    Acta Crystallographica Section E Structure Reports Online, 2011
  • 2-[5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]-6-methyl-1, 3-benzothiazole
    Hoong-Kun Fun, Suhana Arshad, M. Himaja, D. Munirajasekhar, B. K. Sarojini
    Acta Crystallographica Section E Structure Reports Online, 2011

RECENT SCHOLAR PUBLICATIONS

  • Insecticidal activity of substituted 1, 3-diynes.
    D Munirajasekhar
    2014
    Citations: 1
  • Development and validation of a headspace gas chromatographic method for the determination of ethyl alcohol in ketorolac tromethamine injection.
    CH Yadav, D Munirajasekhar
    Journal of Chemical & Pharmaceutical Research 6 (7) , 2014
    2014
  • Synthesis of New (Pyrazol‐3‐yl)‐1,3,4‐oxadiazole Derivatives by Unexpected Aromatization During Oxidative Cyclization of 4,5‐Dihydro‐1 H ‐pyrazole‐3 …
    K Jagadeesh Prathap, M Himaja, SV Mali, D Munirajasekhar
    Journal of Heterocyclic Chemistry 51 (3), 726-732 , 2014
    2014
    Citations: 12
  • A Facile and Efficient Synthesis of 2‐(5‐(4‐Substitutedphenyl)‐4, 5‐dihydro‐3‐phenylpyrazol‐1‐yl)‐6‐Substitutedbenzothiazoles and Their Biological Studies
    D Munirajasekhar, M Himaja, SV Mali
    Journal of Heterocyclic Chemistry 51 (2), 459-465 , 2014
    2014
    Citations: 19
  • Copper (I) assisted catalyst synthesis of substituted allenes and their biological studies
    K Mohankumar, D Munirajasekhar, S Bhattacharya, K Chandrasekaran
    2014
  • Synthesis, Docking and Biological Studies of the Linear Tetrapeptide PWPV-A Potent Insecticidal Agent
    M Himaja, S Sharma, P Das, A Karigar, D Munirajasekhar
    Int J Pharma Pharma Sci 5 (1), 156-159 , 2013
    2013
    Citations: 3
  • Synthesis and biological evaluation of some n-methylated derivatives of thiazolylamino acids and peptides.
    M Himaja, GN Gupta Nitesh, D Munirajasekhar, KA Karigar Asif, ...
    2012
    Citations: 10
  • 1-(6-Fluoro-1, 3-benzothiazol-2-yl)-2-(1-phenylethylidene) hydrazine
    HK Fun, CK Quah, D Munirajasekhar, M Himaja, BK Sarojini
    Structure Reports 68 (8), o2438-o2439 , 2012
    2012
    Citations: 4
  • SYNTHESIS, DOCKING AND ANTIOXIDANT ACTIVITY OF SOME NSAID DERIVATIVES OF AMINES.
    M Himaja, P Das, PK Rout, S Sharma, D Munirajasekhar, AA Karigar
    International Journal of Research in Ayurveda & Pharmacy 3 (4) , 2012
    2012
    Citations: 8
  • Synthesis of novel azetidinone derivatives as antitubercular agents
    M Himaja, A Karigar, M V Ramana, D Munirajasekhar, M S Sikarwar
    Letters in Drug Design & Discovery 9 (6), 611-617 , 2012
    2012
    Citations: 18
  • Synthesis of Glabrin A and its N-methylated analog as potent insecticidal agents.
    M Himaja, G Vani, MV Ramana, KA Karigar Asif, D Munirajasekhar
    2012
    Citations: 2
  • Synthesis, anthelmintic, insecticidal activity of (E)-1-((1-(6-chlorobenzo[d]thiazol-2-yl)-3-phenyl-1 H -pyrazol-4-yl)methylene)-2-(6-substituted benzo[d]thiazol-2-yl …
    M Himaja, D Munirajasekhar, AK Asif Karigar, MV Ramana, ...
    2012
    Citations: 4
  • SYNTHESIS AND EVALUATION OF ANTITUBERCULAR ACTIVITY OF SOME LAMIVUDINE BASED HYBRID DRUGS.
    M Himaja, MV Simha, D Munirajasekhar, A Karigar, M Mahima
    International Journal of Research in Ayurveda & Pharmacy 3 (2) , 2012
    2012
    Citations: 2
  • Synthesis and antioxidant activity of 4, 6–diphenylpyrimidine-2-amine & its derivatives
    M Himaja, PK Rout, AA Karigar, D Poppy, D Munirajashekhar
    Univ J Pharm 2012; 01 (01): 72 77 , 2012
    2012
    Citations: 8
  • 1-(6-Fluoro-1, 3-benzothiazol-2-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde
    HK Fun, CW Ooi, D Munirajasekhar, M Himaja, BK Sarojini
    Structure Reports 67 (12), o3458-o3459 , 2011
    2011
    Citations: 2
  • Synthesis and anthelmintic activity of 6-substituted 2-hydrazino-1, 3-benzothiazoles.
    D Munirajasekhar, M Himaja, SV Mali, AK Asif Karigar, ...
    2011
    Citations: 6
  • 7-Chloro-3-phenylbenzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazole
    HK Fun, SIJ Asik, M Himaja, D Munirajasekhar, BK Sarojini
    Structure Reports 67 (10), o2810-o2810 , 2011
    2011
    Citations: 9
  • 2-[5-(4-Methoxyphenyl)-3-phenyl-4, 5-dihydro-1H-pyrazol-1-yl]-6-methyl-1, 3-benzothiazole
    HK Fun, S Arshad, M Himaja, D Munirajasekhar, BK Sarojini
    Structure Reports 67 (9), o2412-o2412 , 2011
    2011
    Citations: 4
  • of Linear Tetrapeptide D-Phe-L-(Ala-Tyr-Val)
    M Himaja, K Sreekanth, D Munirajasekhar, MV Ramana, M Sikarwar
    Journal of Pharmacy Research 4 (8), 2581-2583 , 2011
    2011
    Citations: 8
  • C. Paul raj and R. Lakshmipathy
    D Munirajasekhar
    International Journal of Research in Ayurveda & Pharmacy 2, 325-327 , 2011
    2011

MOST CITED SCHOLAR PUBLICATIONS

  • Synthesis and anthemintic activity of 2-amino-6-subtituted benzothiazoles
    D Munirajasekar, M Himaja, M Sunil
    International research journal of pharmacy 2 (1), 114-117 , 2011
    2011
    Citations: 80
  • A Facile and Efficient Synthesis of 2‐(5‐(4‐Substitutedphenyl)‐4, 5‐dihydro‐3‐phenylpyrazol‐1‐yl)‐6‐Substitutedbenzothiazoles and Their Biological Studies
    D Munirajasekhar, M Himaja, SV Mali
    Journal of Heterocyclic Chemistry 51 (2), 459-465 , 2014
    2014
    Citations: 19
  • Synthesis of novel azetidinone derivatives as antitubercular agents
    M Himaja, A Karigar, M V Ramana, D Munirajasekhar, M S Sikarwar
    Letters in Drug Design & Discovery 9 (6), 611-617 , 2012
    2012
    Citations: 18
  • Synthesis of New (Pyrazol‐3‐yl)‐1,3,4‐oxadiazole Derivatives by Unexpected Aromatization During Oxidative Cyclization of 4,5‐Dihydro‐1 H ‐pyrazole‐3 …
    K Jagadeesh Prathap, M Himaja, SV Mali, D Munirajasekhar
    Journal of Heterocyclic Chemistry 51 (3), 726-732 , 2014
    2014
    Citations: 12
  • Synthesis and biological evaluation of some n-methylated derivatives of thiazolylamino acids and peptides.
    M Himaja, GN Gupta Nitesh, D Munirajasekhar, KA Karigar Asif, ...
    2012
    Citations: 10
  • 7-Chloro-3-phenylbenzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazole
    HK Fun, SIJ Asik, M Himaja, D Munirajasekhar, BK Sarojini
    Structure Reports 67 (10), o2810-o2810 , 2011
    2011
    Citations: 9
  • Synthesis and biological evaluation of indole-3-carboxylic acid derivatives of amino acids and peptides
    M Himaja, T Jose, MV Ramana, R Anand, D Munirajasekhar
    Int. Res. J. Pharm 1, 436-440 , 2010
    2010
    Citations: 9
  • SYNTHESIS, DOCKING AND ANTIOXIDANT ACTIVITY OF SOME NSAID DERIVATIVES OF AMINES.
    M Himaja, P Das, PK Rout, S Sharma, D Munirajasekhar, AA Karigar
    International Journal of Research in Ayurveda & Pharmacy 3 (4) , 2012
    2012
    Citations: 8
  • Synthesis and antioxidant activity of 4, 6–diphenylpyrimidine-2-amine & its derivatives
    M Himaja, PK Rout, AA Karigar, D Poppy, D Munirajashekhar
    Univ J Pharm 2012; 01 (01): 72 77 , 2012
    2012
    Citations: 8
  • of Linear Tetrapeptide D-Phe-L-(Ala-Tyr-Val)
    M Himaja, K Sreekanth, D Munirajasekhar, MV Ramana, M Sikarwar
    Journal of Pharmacy Research 4 (8), 2581-2583 , 2011
    2011
    Citations: 8
  • Synthesis and anthelmintic activity of 6-substituted 2-hydrazino-1, 3-benzothiazoles.
    D Munirajasekhar, M Himaja, SV Mali, AK Asif Karigar, ...
    2011
    Citations: 6
  • 1-(6-Fluoro-1, 3-benzothiazol-2-yl)-2-(1-phenylethylidene) hydrazine
    HK Fun, CK Quah, D Munirajasekhar, M Himaja, BK Sarojini
    Structure Reports 68 (8), o2438-o2439 , 2012
    2012
    Citations: 4
  • Synthesis, anthelmintic, insecticidal activity of (E)-1-((1-(6-chlorobenzo[d]thiazol-2-yl)-3-phenyl-1 H -pyrazol-4-yl)methylene)-2-(6-substituted benzo[d]thiazol-2-yl …
    M Himaja, D Munirajasekhar, AK Asif Karigar, MV Ramana, ...
    2012
    Citations: 4
  • 2-[5-(4-Methoxyphenyl)-3-phenyl-4, 5-dihydro-1H-pyrazol-1-yl]-6-methyl-1, 3-benzothiazole
    HK Fun, S Arshad, M Himaja, D Munirajasekhar, BK Sarojini
    Structure Reports 67 (9), o2412-o2412 , 2011
    2011
    Citations: 4
  • Synthesis, Docking and Biological Studies of the Linear Tetrapeptide PWPV-A Potent Insecticidal Agent
    M Himaja, S Sharma, P Das, A Karigar, D Munirajasekhar
    Int J Pharma Pharma Sci 5 (1), 156-159 , 2013
    2013
    Citations: 3
  • Synthesis of Glabrin A and its N-methylated analog as potent insecticidal agents.
    M Himaja, G Vani, MV Ramana, KA Karigar Asif, D Munirajasekhar
    2012
    Citations: 2
  • SYNTHESIS AND EVALUATION OF ANTITUBERCULAR ACTIVITY OF SOME LAMIVUDINE BASED HYBRID DRUGS.
    M Himaja, MV Simha, D Munirajasekhar, A Karigar, M Mahima
    International Journal of Research in Ayurveda & Pharmacy 3 (2) , 2012
    2012
    Citations: 2
  • 1-(6-Fluoro-1, 3-benzothiazol-2-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde
    HK Fun, CW Ooi, D Munirajasekhar, M Himaja, BK Sarojini
    Structure Reports 67 (12), o3458-o3459 , 2011
    2011
    Citations: 2
  • Insecticidal activity of substituted 1, 3-diynes.
    D Munirajasekhar
    2014
    Citations: 1
  • Development and validation of a headspace gas chromatographic method for the determination of ethyl alcohol in ketorolac tromethamine injection.
    CH Yadav, D Munirajasekhar
    Journal of Chemical & Pharmaceutical Research 6 (7) , 2014
    2014