RECENT SCHOLAR PUBLICATIONS
- Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in β-arrestin 1/2 signalingS Lei, Q Meng, Y Liu, Q Liu, A Dai, X Cai, MW Wang, Q Zhou, H Zhou, ...European Journal of Pharmacology, 176419 2024
- Metabolism-guided development of Ko143 analogs as ABCG2 inhibitorsJ Zhu, S Lei, J Lu, Y Hao, Q Qian, AS Devanathan, Z Feng, XQ Xie, P Wipf, ...European Journal of Medicinal Chemistry 259, 115666 2023
- Activation of PXR causes drug interactions with Paxlovid in transgenic miceS Lei, A Guo, J Lu, Q Qi, AS Devanathan, J Zhu, X MaActa Pharmaceutica Sinica B 13 (11), 4502-4510 2023
- Identification of PXR activators from Uncaria rhynchophylla (Gou Teng) and Uncaria tomentosa (Cat’s Claw)S Lei, J Lu, A Cheng, Z Hussain, K Tidgewell, J Zhu, X MaDrug Metabolism and Disposition 51 (5), 629-636 2023
- Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice)A Cheng, S Lei, J Zhu, J Lu, MF Paine, W Xie, X MaLiver Research 6 (4), 251-257 2022
- Iron metabolism mediates the relationship between Vitamin C and hepatic steatosis and fibrosis in NAFLDZ Hu, Y Li, B Ma, S Lei, X WangFrontiers in Nutrition 9, 952056 2022
- Precise druggability of the PTH type 1 receptorI Sutkeviciute, JY Lee, AD White, CS Maria, KA Pea, S Savransky, ...Nature chemical biology 18 (3), 272-280 2022
- LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3J Li, X Quan, S Lei, G Chen, J Hong, Z Huang, Q Wang, W Song, X YangEnvironmental Pollution 293, 118542 2022
- PPARγ regulates triclosan induced placental dysfunctionJ Li, X Quan, Y Zhang, T Yu, S Lei, Z Huang, Q Wang, W Song, X Yang, ...Cells 11 (1), 86 2021
- Role of CYP2A6 in methimazole bioactivation and hepatotoxicityJ Li, Z Hussain, J Zhu, S Lei, J Lu, X MaChemical research in toxicology 34 (12), 2534-2539 2021
- Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activationAD White, KA Pea, LJ Clark, CS Maria, S Liu, FG Jean-Alphonse, JY Lee, ...Science signaling 14 (703), eabc5944 2021
- PFOS Inhibited Normal Functional Development of Placenta Cells via PPARγ SignalingJ Li, X Quan, S Lei, Z Huang, Q Wang, P XuBiomedicines 9 (6), 677 2021
- Clinical perspectives of isoniazid-induced liver injuryS Lei, R Gu, X MaLiver Research 5 (2), 45-52 2021
- Precision druggability of a class B GPCR, the PTH type 1 receptorI Sutkeviciute, JY Lee, A White, P Doruker, K Pena, S Sanker, S Lei, ...The FASEB Journal 35 2021
- Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formationLJ Clark, J Krieger, AD White, V Bondarenko, S Lei, F Fang, JY Lee, ...Nature chemical biology 16 (10), 1096-1104 2020
- Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonismS Lei, L Clydesdale, A Dai, X Cai, Y Feng, D Yang, YL Liang, C Koole, ...Journal of Biological Chemistry 293 (24), 9370-9387 2018
- Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complexYL Liang, M Khoshouei, A Glukhova, SGB Furness, P Zhao, L Clydesdale, ...Nature 555 (7694), 121-125 2018
- A historic study that opened a new chapter in nutritional scienceS Lei, D Yang, M WangActa Pharmacologica Sinica 37 (12), 1641-1644 2016
- G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cellsC Zhou, X Dai, Y Chen, Y Shen, S Lei, T Xiao, T Bartfai, J Ding, MW WangOncotarget 7 (11), 12823 2016
- Application of chemical biology in target identification and drug discoveryY Zhu, T Xiao, S Lei, F Zhou, MW WangArchives of pharmacal research 38, 1642-1650 2015
