Durga Ray

RESEARCH INTERESTS

Microbiology, Molecular and Microbial Biological Techniques, Protein Expression, Biological Control

Scopus Publications

The soil bacterium, Corynebacterium glutamicum, from biosynthesis of value-added products to bioremediation: A master of many trades
Durga Ray, Uttpal Anand, Niraj Kumar Jha, Ewa Korzeniewska, Elza Bontempi, Jarosław Proćków, and Abhijit Dey
Elsevier BV



Podophyllum hexandrum and its active constituents: Novel radioprotectants
Uttpal Anand, Protha Biswas, Vinay Kumar, Durga Ray, Puja Ray, Verity I.P. Loake, Ramesh Kandimalla, Anupama Chaudhary, Birbal Singh, Nanda Kishore Routhu,et al.
Elsevier BV



Role of Polyamines in Molecular Regulation and Cross-Talks Against Drought Tolerance in Plants
Samapika Nandy, Saynati Mandal, Santosh Kumar Gupta, Uttpal Anand, Mimosa Ghorai, Avinash Mundhra, Md. Habibur Rahman, Puja Ray, Sicon Mitra, Durga Ray,et al.
Springer Science and Business Media LLC



Biotechnological interventions of in vitro propagation and production of valuable secondary metabolites in Stevia rebaudiana
Shahnawaz, Devendra Kumar Pandey, Merinashwari Konjengbam, Padmanabh Dwivedi, Prabhjot Kaur, Vijay Kumar, Durga Ray, Puja Ray, Romaan Nazir, Harmeet Kaur,et al.
Springer Science and Business Media LLC



Bacosides from Bacopa monnieri extract: An overview of the effects on neurological disorders
Samarpita Banerjee, Uttpal Anand, Suchhanda Ghosh, Durga Ray, Puja Ray, Samapika Nandy, Ganpat Dewaji Deshmukh, Vijay Tripathi, and Abhijit Dey
Wiley
From ancient history, complementary and alternative medicines have played a significant role as holistic therapeutic treatments of various human diseases including cancer, diabetes, neurological diseases, and skin problems. One Indian medicinal plant (herb), Bacopa monnieri has been used in many parts of the world as such medicine, particularly for the treatment of various neurological disorders. It is well known as a potent “tonic for the human brain,” which serves as a memory enhancer. Multiple studies proved that this herb contains a plethora of potential bioactive, phytochemical compounds with synergistic properties. The main purpose of the present review is to shed light on the use of Bacopa monnieri and its active principles (bacosides) in the management of neurological disorders. Furthermore, the signaling pathways modulated by bacosides have been critically discussed in this review. Moreover, we have critically summarized the present knowledge of this perennial creeping herb based upon the literature mining from different scientific engines.


Identification of the regulators binding to the upstream region of glxR in Corynebacterium glutamicumS
Bindu Subhadra, Durga Ray, Jong Yun Han, Kwang-Hee Bae, and Jung-Kee Lee
Journal of Microbiology and Biotechnology
GlxR is considered as a global transcriptional regulator controlling a large number of genes having broad physiological aspects in Corynebacterium glutamicum. However, the expression profile revealing the transcriptional control of glxR has not yet been studied in detail. DNA affinity chromatography experiments revealed the binding of transcriptional regulators SucR, RamB, GlxR, and a GntR-type protein (hereafter denoted as GntR3) to the upstream region of glxR. The binding of different regulators to the glxR promoter was confirmed by EMSA experiments. The expression of glxR was analyzed in detail under various carbon sources in the wild-type and different mutant strains. The sucR and gntR3 deletion mutants showed decreased glxR promoter activities, when compared with the wild type, irrespective of the carbon sources. The promoter activity of glxR was derepressed in the ramB deletion mutant under all the tested carbon sources. These results indicate that SucR and GntR3 are acting as activators of GlxR, while RamB plays a repressor. As expected, the expression of glxR in the cyaB and glxR deletion mutants was derepressed under different media conditions, indicating that GlxR is autoregulated.