Hilal KOCDOR

@deu.edu.tr

Dokuz Eylul University Oncology Institute Department of Basic Oncology
Dokuz Eylul University



              

https://researchid.co/hilal.kocdor
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Scopus Publications

12

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Scopus Publications

  • A promising biomarker to distinguish benign and malignant renal tumors: Elabela
    G. Artaş, T. Kuloğlu, A. Dağlı, K. Ugur, M. Yardim, S. Aydin, H. Artaş and H. Koçdor

    Aim: The aim of this study was to investigate ELABELA (ELA) expression in benign and malignant renal tissues and expression differences in different nuclear grades of clear cell carcinomas. Materials and Methods: Patients that underwent surgery due to renal masses between the years of 2007 and 2017 were used. Control renal tissues (n = 23), papillary RCC (n = 23), clear cell RCC (CcRCC) [Fuhrman Grade1 (n = 23), Fuhrman Grade2 (n = 23), Fuhrman Grade3 (n = 23), Fuhrman Grade4 (n = 23)], and chromophobe RCC (n = 23) were included to the study. The Independent samples t-test was used for 2-point intergroup assessments and the one-way analysis of variance and posthoctukey test was used for the others. Values of P < 0.05 were considered statistically significant. Results: ELA immunoreactivity was observed in proximal and distal tubules in the kidney, but not in glomeruli in control tissues. When compared with control kidney tissue, a statistically significant increase was observed in ELA immunoreactivity in renal oncocytoma. In the chromophobe RCC, ELA immunoreactivity was significantly lower than control kidney tissue, whereas papillary RCC did not show ELA immunoreactivity. However, compared with control kidney tissue, ELA immunoreactivity was not observed in Fuhrman Grade 1 and Grade 2 CcRCC. Also, there was a significant decrease at Fuhrman Grade 3 and Grade 4 CcRCC compared with control kidney tissues. In the statistical analysis of ELA immunoreactivity among the Fuhrman nuclear grades of CcRCCs, The ELA immunoreactivity was higher at Grade 4 CcRCC than Grade 1, Grade 2, and Grade 3. Conclusion: ELA is a usefull molecule to differentiate benign and malign renal tumors. But further broad and comprehensive studies are needed to investigate cellular and molecular mechanisms of ELAs on malign transformation.

  • Inhibition of cancer stem-like phenotype by curcumin and deguelin in CAL-62 anaplastic thyroid cancer cells
    Mehmet A. Kocdor, Hakan Cengiz, Halil Ates, and Hilal Kocdor
    Bentham Science Publishers Ltd.
    Background:Anaplastic Thyroid Cancer (ATC) is one of the most lethal and aggressive human malignancies. Studies have shown that Cancer Stem-Cell (CSC) phenotype is mainly responsible for ATC aggressiveness. Cytostatic compounds are mostly ineffective because of multidrug resistance mechanisms driven by the CSC phenotype. Taxanes have limited efficacy. Recently, CSC inhibition using plant-derived, less toxic compounds, which have anti-cancer efficacy, has become a novel treatment modality. The aim of the study was to evaluate the anti-cancer activity of two natural compounds (curcumin and deguelin) on ATC cells and their CSC properties. In addition, the efficacies of these compounds were compared with that of docetaxel.Methods:Besides control, five treatment groups were formed. ATC cells (CAL-62) were treated with curcumin, deguelin, docetaxel, and their combinations (curcumin+docetaxel, deguelin+docetaxel) at previously determined IC50 doses. Stemness was analyzed by quantitative estimation of sphere formation in matrigel, expression of several cell surface markers (CD133, CD90, Nanog, and OCT3/4) using flow cytometry, and quantification of the hypoxic status [Oxidative Stress Index (OSI) and Superoxide Dismutase (SOD) activity]. The anti-cancer efficacies of these compounds and their combinations were evaluated by determining the alterations in the cell cycle, apoptosis, and tumoral cell migration.Results:Both the natural compounds (particularly curcumin) significantly suppressed the spheroid formation and cellular motility in matrigel as well as suppressed the accumulation of cells in the G0/1 phase, in which the maximum CSC activity is observed. The compounds did not suppress the expression of CSC markers, but twothirds of the cells expressed CD90. Deguelin was found to be particularly effective in inducing apoptosis similar to docetaxel at IC50 concentrations. Curcumin reduced the OSI and deguelin enhanced the SOD activity, even in docetaxel pre-treated cells.Conclusion:A large proportion of anaplastic tumors might consist of heterogeneous CSC population. Curcumin and deguelin have anti-cancer and several anti-stem cell activities against ATC cells. These natural compounds are capable of altering the aggressive behavior of ATC cells through the inhibition of the CSC phenotype. As a novel therapeutic target, CD90 should be investigated in other ATC cell lines and in vivo models.

  • The report of the 1st Turkey in vitro diagnostic symposium results
    Hilal Kocdor, Ebru Sezer, Zubeyde Erbayraktar, Aysun Pabuccuoglu, Taner Onat, Gulgun Oktay, Gul Guner, Nilgun Yener, Ferhan Sagin, and Diler Aslan
    Walter de Gruyter GmbH
    Abstract“The 1st Turkish in vitro Diagnostic Symposium” was organized in İzmir between the dates 18–20 February 2016 with cooperation of Turkish Biochemistry Society Izmir Branch and Dokuz Eylul University Institute of Health Sciences. This article presents a collection of the subjects, recommendations and results included in the final report of the symposium. Symposium subjects were analysed under separate titles and evaluated together with results obtained from various reports on medical devices (MD) in the last decade. According to the final report, the subjects to be considered on preferential basis include “configuration of the websites of legal authorities, standardization and accreditation institutions in a way to access work on in vitro Diagnostic (IVD)”, “activation of university-industry cooperation”, “determination of national standards parallel to international standards” and “carrying out the statistics about IVD-MD in Turkey as immediate as possible”. Drawing attention to the fact that there is a requirement for competent man power for every-stage of IVD-MD lifecycle, it is recommended that postgraduate education programmes are founded to serve these fields. Consequently, this symposium enabled to determine the basic problems about the sector by bringing together the stakeholders related to IVD-MD field and to come up with an action plan in accordance with the recommendations.

  • Evaluation of the first Turkish in vitro diagnostic symposium
    Fadime Aydin Kose, Serap Celebi, Hakan Cengiz, Duygu Harmanci, Ayse Kocak, Erhan Canbay, Diler Aslan, Ebru Sezer, Aysun Pabuccuoglu, and Hilal Kocdor
    Walter de Gruyter GmbH
    Abstract:In vitro diagnostic (IVD) medical laboratory devices, tests and equipment are closely related with public health, patient safety and the safety of all who utilize these tools in laboratories. The close monitoring of the process from the production line to the end-point user is crucial so that IVD devices and tests do not pose a risk to individuals and society. Based on this background, the “First Turkish in vitro Diagnostic Symposium: Medical Laboratory Tests” was held in February, 2016. The symposium was organized by the cooperation of Turkish Biochemical Society, Izmir Branch and Dokuz Eylul University Health Sciences Institute along with the contributions of TurkLab Calibration Association. It was intended that the meeting would shed light on questions such as, ‘What is the place and importance of IVD in Turkey?’, ‘What are the responsibilities of educational institutions?’, ‘What is the role of Ministry of Health?’, with the aim that the answers would help to determine the infrastructure needed for successful production of IVD medical devices in Turkey. At the end of the symposium, feedback from participants were collected via a questionnaire. This article presents the general evaluation of the symposium based on the results of this survey.

  • Irisin immunohistochemistry in gastrointestinal system cancers
    S Aydin, T Kuloglu, MR Ozercan, S Albayrak, S Aydin, U Bakal, M Yilmaz, M Kalayci, M Yardim, M Sarac,et al.
    Informa UK Limited
    Cancer is the leading cause of morbidity and mortality worldwide. Some studies have shown that high heat kills cancer cells. Irisin is a protein involved in heat production by converting white into brown adipose tissue, but there is no information about how its expression changes in cancerous tissues. We used irisin antibody immunohistochemistry to investigate changes in irisin expression in gastrointestinal cancers compared to normal tissues. Irisin was found in human brain neuroglial cells, esophageal epithelial cells, esophageal epidermoid carcinoma, esophageal adenocarcinoma and neuroendocrine esophageal carcinoma, gastric glands, gastric adenosquamous carcinoma, gastric neuroendocrine carcinoma, gastric signet ring cell carcinoma, neutrophils in vascular tissues, intestinal glands of colon, colon adenocarcinoma, mucinous colon adenocarcinoma, hepatocytes, hepatocellular carcinoma, islets of Langerhans, exocrine pancreas, acinar cells and interlobular and interlobular ducts of normal pancreas, pancreatic ductal adenocarcinoma, and intra- and interlobular ducts of cancerous pancreatic tissue. Histoscores (area × intensity) indicated that irisin was increased significantly in gastrointestinal cancer tissues, except liver cancers. Our findings suggest that the relation of irisin to cancer warrants further investigation.

  • Zinc supplementation induces apoptosis and enhances antitumor efficacy of docetaxel in non-small-cell lung cancer
    Hilal Kocdor, Halil Ates, Suleyman Aydin, Ruksan Cehreli, Firat Soyarat, Pinar Kemanli, Duygu Harmanci, Hakan Cengiz, and Mehmet Kocdor
    Informa UK Limited
    Background Exposure to exogenous zinc results in increased apoptosis, growth inhibition, and altered oxidative stress in cancer cells. Previous studies also suggested that zinc sensitizes some cancer cells to cytotoxic agents depending on the p53 status. Therefore, zinc supplementation may show anticancer efficacy solely and may increase docetaxel-induced cytotoxicity in non-small-cell lung cancer cells. Methods Here, we report the effects of several concentrations of zinc combined with docetaxel on p53-wild-type (A549) and p53-null (H1299) cells. We evaluated cellular viability, apoptosis, and cell cycle progression as well as oxidative stress parameters, including superoxide dismutase, glutathione peroxidase, and malondialdehyde levels. Results Zinc reduced the viability of A549 cells and increased the apoptotic response in both cell lines in a dose-dependent manner. Zinc also amplified the docetaxel effects and reduced its inhibitory concentration 50 (IC50) values. The superoxide dismutase levels increased in all treatment groups; however, glutathione peroxidase was slightly increased in the combination treatments. Zinc also caused malondialdehyde elevations at 50 μM and 100 μM. Conclusion Zinc has anticancer efficacy against non-small-cell lung cancer cells in the presence of functionally active p53 and enhances docetaxel efficacy in both p53-wild-type and p53-deficient cancer cells.

  • Progressive increase of glucose transporter-3 (GLUT-3) expression in estrogen-induced breast carcinogenesis
    M. A. Kocdor, H. Kocdor, J. S. Pereira, J. E. Vanegas, I. H. Russo, and J. Russo
    Springer Science and Business Media LLC

  • Ghrelin expression of endometrium hyperplasia and endometrioid carcinoma
    Adile F. Dagli, Suleyman Aydin, Hilal Kocdor, Bilgin Gurates, İbrahim Sahin, Zekiye Catak, Mehmet R. Ozercan, and İbrahim. H. Ozercan
    Informa UK Limited
    Background. Endometrium carcinoma ranks fourth among female carcinomas. Therefore, early diagnosis of endometrium pre-malignant lesions is emphasised, and attempts are made to identify the risk factors. Since hyperplasias, particularly those with atypia, are held responsible for the development of the most common endometrium carcinomas, it is important to definitely distinguish between well-differentiated carcinomas and hyperplasia with atypia. In the present study, we aimed to explore whether ghrelin expression had a role in distinguishing between benign, pre-malignant and malignant lesions of endometrium. Methods. Tissue ghrelin expressions of a total of 60 cases, who were diagnosed in the Pathology Department Laboratory of Fırat University Medical School, and of whom 10 were in the proliferation phase, 10 had simple hyperplasia without atypia, 10 had simple hyperplasia with atypia, 10 had complex hyperplasia without atypia, 10 had complex hyperplasia with atypia and 10 had endometrioid carcinoma cases, were examined using immunohistochemical method. Additionally, tissue samples were homogenised to analyse tissue ghrelin levels in the supernatants according to RIA method. Samples from the parotid glands were used as positive control for ghrelin. Cells that exhibited cytoplasmic staining with ghrelin antibody were evaluated as positive. Results. Immunohistochemical examination showed that ghrelin expression increased markedly in the proliferation phase, relative to hyperplasias and carcinoma. These results were parallel to ghrelin levels in tissue supernatants. Immunohistochemical and RIA analysis results indicate that ghrelin expression either markedly decreases or is entirely depleted in endometrial carcinomas. Conclusions. Therefore, we think that ghrelin expression can be useful in differentiating not only endometrium carcinomas from benign lesions but also complex hyperplasias with atypia, which pose diagnostic difficulties.

  • The effects of parenteral glutamine on intestinal adaptation in a rat model of short bowel syndrome
    Ahmet Ucar, Hilal Kocdor, Aras Canda, Sadiye Unlu, Ruksan Cehreli, and Mehmet Kocdor
    Walter de Gruyter GmbH
    Abstract Short bowel syndrome (SBS) is characterized by the malabsorption of nutrients and fluids that occurs after major intestinal resection, resulting from an adaptation process that begins immediately to increase the mucosal surface area and absorption. Certain nutrients and trophic factors are widely used to increase intestinal adaptation following massive intestinal resection. The efficacy and benefits of glutamine on the intestinal adaptation process is still controversial. This study was conducted to determine the effects of parenteral glutamine administration on intestinal adaptation in a rat model of SBS. Fourteen male Wistar rats were divided into two groups; all 14 underwent 75% small bowel resection. Within each group, rats were assigned to 14 days of treatment with subcutaneous glutamine (0.3 g/kg/day) or isotonic saline daily. Weight changes and histological intestinal adaptation parameters (mucosal thickness, villus height, and crypt depth) were measured. Non-mucosal intestinal changes were evaluated by intestinal fractioned collagen analysis. All rats initially lost weight and began to gain weight postoperatively; however, they did not reach their preoperative weights during the experiment and there was no significant difference between the groups. Histological adaptation parameters were significantly increased after 75% intestinal resection in both groups compared to paired native samples (P&lt;0.01); although the percent of increase was slightly higher in Gln group, no significant difference was detected between the two groups. Fractioned-collagen amounts were found to be similar between groups. The results indicated that parenteral glutamine administration alone does not improve the intestinal adaptation process after massive intestinal resection in rats.

  • Human chorionic gonadotropin (hCG) prevents the transformed phenotypes induced by 17 β-estradiol in human breast epithelial cells
    Hilal Kocdor, Mehmet A. Kocdor, Jose Russo, Kara E. Snider, Johana E. Vanegas, Irma H. Russo, and Sandra V. Fernandez
    Wiley

  • Chemopreventive efficacies of rosiglitazone, fenretinide and their combination against rat mammary carcinogenesis
    Hilal Kocdor, Mehmet Ali Kocdor, Tulay Canda, Duygu Gurel, Ruksan Cehreli, Osman Yilmaz, Mehmet Alakavuklar, and Gul Guner
    Springer Science and Business Media LLC

  • The effects of selenium against cerebral ischemia-reperfusion injury in rats
    Seda Özbal, Güven Erbil, Hilal Koçdor, Kazım Tuğyan, Çetin Pekçetin, and Candan Özoğul
    Elsevier BV

  • Effects of locally applied 5-fluorouracil on the prevention of postmastectomy seromas in a rat model
    M.A. Kocdor, D. Kilic Yildiz, H. Kocdor, T. Canda, O. Yilmaz, G. Oktay, and O. Harmancioglu
    S. Karger AG
    &lt;i&gt;Backgrounds:&lt;/i&gt; Seroma formation is the most common complication following mastectomy and axillary dissection (AD). Currently available interventions have aimed at obliterating dead space by inducing fibrosis and through various mechanical methods. Here, 5-fluorouracil (5-FU), used as a sclerosing agent for the prevention of seroma formation, was investigated in a rat mastectomy model. &lt;i&gt;Methods:&lt;/i&gt; 20 rats were divided into two groups (5-FU and control). All rats underwent mastectomy and AD. Immediately following the operation, equal volumes of saline and 5-FU were administered under the surgical flaps. One week after the operation, seroma formation and wound-healing processes were evaluated using histopathological and biochemical investigations. &lt;i&gt;Results:&lt;/i&gt; 5-FU did not act as a sclerosing agent, yet it was highly effective in preventing seroma formation. The intensity of acute inflammation, vascularity, as well as leukocyte and fibroblast infiltration, were significantly lower in the 5-FU group than the control; the tissue collagen fractions and total seroma collagen contents were found to be similar between the two groups. &lt;i&gt;Conclusions:&lt;/i&gt; The mechanisms underlying seroma prevention by 5-FU are probably related to a decrease in the inflammation and angiogenesis rather than a local fibrotic process. Seroma formation may be due to a prolonged inflammatory phase of wound healing.

  • Toxicity induced by the chemical carcinogen 7,12-dimethylbenz[a]anthracene and the protective effects of selenium in wistar rats
    Hilal Kocdor, Ruksan Cehreli, Mehmet Ali Kocdor, Banu Sis, Osman Yilmaz, Tulay Canda, Binnaz Demirkan, Halil Resmi, Mehmet Alakavuklar, and Omer Harmancioglu
    Informa UK Limited
    7,12-Dimethylbenz[a]anthracene (DMBA), a polycyclic aromatic hydrocarbon (PAH), has been used extensively as a tool to initiate mammary carcinogenesis and subsequent chemoprevention. On the other hand, selenium (Se) is potentially useful in oncology because this element possesses anticarcinogenic and chemopreventive properties. Se-containing enzymes such as glutathione peroxidase (GPx) play an important role in PAH metabolism and detoxification. In this study, rats were administered a single, oral dose of DMBA (12 mg). In the Se group, rats received 20 µg Se daily via gavage, starting 2 wk before the DMBA administration and continued for 1 wk. One hundred twenty days after DMBA administration the rats were sacrificed and toxicity was evaluated using histopathological and biochemical criteria. Five rats (30%) died in the DMBA group within the study period, whereas no death occurred in the DMBA–Se-treated group. Malignant tumor frequency was 33% in the DMBA group, while no malignant tumors occurred in the DMBA–Se-treated group. Some inflammatory changes rather than epithelial changes were found upon histopathological examination. GPx activity and blood urea nitrogen levels were higher and kidney GST activity was lower in the DMBA–Se-treated group compared to DMBA alone. In conclusion, Se appears to be effective in preventing some of the adverse effects associated with DMBA. This research has been partially carried out at Dokuz Eylul University School of Medicine, Learning Resources Center Research Laboratory (ARLAB). The authors thank Dr. Ali Riza Sisman for his kind contributions and Prof. Dr. Gul Guner and Dr. Sam Kacew for their helpful advice.

  • Improvement of colonic healing by preoperative rectal irrigation with short-chain fatty acids in rats given radiotherapy
    Cem Terzi, Ali İbrahim Sevinç, Hilal Koçdor, Gülgün Oktay, Hilmi Alanyal, Ali Küpelioğlu, Gül Ergör, and Mehmet Füzün
    Ovid Technologies (Wolters Kluwer Health)

  • The effects of vascular bed expansion in steatotic rat liver graft viability
    Koray Atila, �zg�l Sagol, Hilal Ko�dor, Ahmet �oker, Ibrahim Astarcioglu, H�seyin Astarcioglu, and Sedat Karademir
    Frontiers Media SA

  • Serum tumor necrosis factor-α, glutamate and lactate changes in two different stages of mechanical intestinal obstruction


  • The effects of pentoxifylline on bacterial translocation after intestinal obstruction
    Mehmet Ali Kocdor, Hilal Kocdor, Zeynep Gulay, and Ozcan Gokce
    Ovid Technologies (Wolters Kluwer Health)
    Bacterial translocation (BT) occurs mainly in preseptic conditions such as intestinal obstruction, trauma, and burn, and the underlying mechanisms are still unclear. Pentoxifylline (PTX) is a derivative of methyl xanthine and has several beneficial effects in sepsis. We investigated the effects of PTX on a rat BT model. Simple intestinal obstruction (IO) was choosen to create high BT rates. Rats were divided in to five groups of 10 rats. Either 50 mg/kg PTX or placebo (3 mg/100 g saline) was administered subcutaneously following IO, either by single injection or twice with a 12-h interval. All rats were sacrificed 12 or 24 h after the procedure, and mesenteric lymph nodes (MLN), liver, and blood samples were obtained under aseptic conditions for bacterial cultures. The samples were obtained 12 h following IO in the first two groups, and the same samples were obtained 24 h after IO in last three groups. Groups IV and V were the PTX treatment groups. PTX was re-injected 12 h after IO only in group IV. As a result, BT rates in MLNs and liver were found to be significantly low, blood specimens remained sterile in PTX-pretreated and -treated rats, and BT rates were high in control groups and group V (once treatment late specimen group). We conclude that simple intestinal obstruction causes BT, and PTX reduces BT in rats with IO during the first 12-h period if PTX is given once immediately following IO. PTX reduces BT during the first 24-h after IO provided that is injected twice with a 12-h interval. More experimental studies are need to explain the exact mechanism of this beneficial effect.

  • Comparison of the effects of propofol, isoflurane and sevoflurane on renin-angiotensin-aldosterone system in rabbits


RECENT SCHOLAR PUBLICATIONS

  • The Effects of Tetrahydrocurcumin on Adriamycin and Taxane resistance in Anaplastic Thyroid Cancer Cells
    K MA, Y KAYA, H ATES, E BILDIK, H KOCDOR
     2024

  • The Effects of Tetrahydrocurcumin on Adriamycin and Taxane resistance in Anaplastic Thyroid Cancer Cells
    MA KOCDOR, K Yagmur, A Halil, E BILDIK, H KOCDOR
     2024

  • THE INVITATION
    D Yucel, H Kocdor
    TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI 48, 7-8 2024

  • Sıvı Biyopsi: in vitro Diyagnostik Aıdan Klinik Uygulamalar, Sorunlar, Beklentiler, Dzenlemeler
    H KODOR, A PABUUOĞLU, F ZİHNİOĞLU
    Turkiye Klinikleri Medical Oncology-Special Topics 16 (1), 1-5 2023

  • Kanserde Tkrk Biyobelirteleri
    H KODOR, A YILDIRIM
    Turkiye Klinikleri Medical Oncology-Special Topics 16 (1), 68-78 2023

  • Tkrk Biyopsisi ve Hastalıkların Tanısındaki nemi
    H KODOR, A YILDIRIM
    Turkiye Klinikleri Medical Oncology-Special Topics 16 (1), 52-67 2023

  • SYMPOSIUM SCIENTIFIC ADVISORY BOARD [SEMPOZYUM BİLİMSEL DANIŞMA KURULU]
    A nl, A Argon, AS Dinel, A Pabucuoğlu, A Demirtaş, B Zengel, ...
    Turk J Biochem 48 (2) 2023

  • INVESTIGATION OF THE ANTIMETASTATIC POTENTIAL OF THYMBRA SPICATA IN HUMAN BREAST ADENOCARCINOMA CELLS COMBINED WITH STANDART CHEMOTHERAPY.
    T SALMAN, A YILDIRIM, MA KOCDOR, Y KAYA, Y SOYSAL, H KOCDOR
    Turkish Journal of Biochemistry/Turk Biyokimya Dergisi 47 2022

  • COMPARISON OF THE EFFECTS OF PISTACIA VERA INNER SHELL OBTAINED FROM DIFFERENT REGIONS OF TURKEY ON OXIDATIVE STRESS AND PROLIFERATION IN INVASIVE BREAST CANCER CELL LINE.
    I GURKEBABCI, B KOCDOR, H ATES, H KOCDOR
    Turkish Journal of Biochemistry/Turk Biyokimya Dergisi 47 2022

  • ANTIMETASTATIC POTENTIAL OF CURCUMIN IN ANAPLASTIC THYROID CANCER AND COMBINED ACTIVITY WITH DOCETAXEL.
    MA KOCDOR, Y Kaya, A YILDIRIM, H Kodor
    Turkish Journal of Biochemistry/Turk Biyokimya Dergisi 47 2022

  • INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE
    İ Grkebabı, B Kocdor, H Kodor
    Sağlık Bilimlerinde İleri Araştırmalar Dergisi 5 (S-1), 59-59 2022

  • Participating in scientific meetings as part of PhD training: 6 years of educational and scientific data
    H Kocdor, D Harmanci, A Pabuccuoglu, F Zihnioglu, N Yener, F Sagin
    FEBS OPEN BIO 12, 335-335 2022

  • COVID-19 Pandemisinde Biyoteknoloji Kullanımı
    H KODOR, İ GRKEBABCI, D HARMANCI
    Turkiye Klinikleri Biomedical-Special Topics 3 (1), 154-168 2022

  • Gemişten Gnmze Biyoteknoloji
    H KODOR
    Turkiye Klinikleri Biomedical-Special Topics 3 (1), 1-10 2022

  • Molekler Karsinogenez ve Kimyasal Karsinojenler
    H KODOR
    Turkiye Klinikleri Medical Oncology-Special Topics 14 (4), 33-40 2021

  • BIOLOGY OF METASTASIS.
    H Kocdor
    Turkish Journal of Biochemistry/Turk Biyokimya Dergisi 45 2020

  • TESTING THE EFFECT OF PRESSURE EXCHANGER SYSTEM ON CANCER CELLS.
    H Cengiz, MA Kodor, H Kodor
    Turkish Journal of Biochemistry/Turk Biyokimya Dergisi 44 2019

  • Inhibition of cancer stem-like phenotype by curcumin and deguelin in CAL-62 anaplastic thyroid cancer cells
    MA Kocdor, H Cengiz, H Ates, H Kocdor
    Anti-Cancer Agents in Medicinal Chemistry-Anti-Cancer Agents) 19 (15), 1887-1898 2019

  • A promising biomarker to distinguish benign and malignant renal tumors: ELABELA
    G Artas, T Kuloglu, AF Dagli, K Ugur, M Yardim, S Aydin, H Artas, ...
    Nigerian Journal of Clinical Practice 22 (3), 386-392 2019

  • HOŞGELDİNİZ MESAJI/WELCOME MESSAGE
    H Kodor, D Ycel
    Turkish Journal of Biochemistry 43 (s1), 5-5 2018

MOST CITED SCHOLAR PUBLICATIONS

  • The effects of selenium against cerebral ischemia-reperfusion injury in rats
    S zbal, G Erbil, H Kodor, K Tuğyan, Peketin, C zoğul
    Neuroscience letters 438 (3), 265-269 2008
    Citations: 113

  • Irisin immunohistochemistry in gastrointestinal system cancers
    S Aydin, T Kuloglu, MR Ozercan, S Albayrak, S Aydin, U Bakal, M Yilmaz, ...
    Biotechnic & Histochemistry 91 (4), 242-250 2016
    Citations: 101

  • Zinc supplementation induces apoptosis and enhances antitumor efficacy of docetaxel in non-small-cell lung cancer
    H Kocdor, H Ates, S Aydin, R Cehreli, F Soyarat, P Kemanli, D Harmanci, ...
    Drug Design, Development and Therapy, 3899-3909 2015
    Citations: 57

  • Dokuz Eyll niversitesi Sağlık Bilimleri Enstitsnde Lisansst eğitim kalitesinin arttırılması kapsamında ğrencilerin eğitime ilişkin grşlerinin değerlendirilmesi
    N DEVEBAKAN, H Kodor, B MUSAL, GL GNER AKDOĞAN
    Dokuz Eyll niversitesi Sosyal Bilimler Enstits 2003
    Citations: 40

  • Improvement of colonic healing by preoperative rectal irrigation with short-chain fatty acids in rats given radiotherapy
    C Terzi, AI Sevin, H Kodor, G Oktay, H Alanyal, A Kpelioglu, G Ergr, ...
    Diseases of the colon & rectum 47 (12), 2184-2194 2004
    Citations: 32

  • Human chorionic gonadotropin (hCG) prevents the transformed phenotypes induced by 17 β-estradiol in human breast epithelial cells
    H Kocdor, MA Kocdor, J Russo, KE Snider, JE Vanegas, IH Russo, ...
    Cell biology international 33 (11), 1135-1143 2009
    Citations: 31

  • The effects of pentoxifylline on bacterial translocation after intestinal obstruction
    MA Kocdor, H Kocdor, Z Gulay, O Gokce
    Shock 18 (2), 148-151 2002
    Citations: 27

  • Effects of locally applied 5-fluorouracil on the prevention of postmastectomy seromas in a rat model
    MA Kocdor, D Kilic Yildiz, H Kocdor, T Canda, O Yilmaz, G Oktay, ...
    European Surgical Research 40 (3), 256-262 2008
    Citations: 26

  • Toxicity induced by he chemical carcinogen 7, 12-dimethylbenz [a] anthracene and the protective effects of selenium in wistar rats
    H Kocdor, R Cehreli, MA Kocdor, B Sis, O Yilmaz, T Canda, B Demirkan, ...
    Journal of Toxicology and Environmental Health, Part A 68 (9), 693-701 2005
    Citations: 26

  • Progressive increase of glucose transporter-3 (GLUT-3) expression in estrogen-induced breast carcinogenesis
    MA Kocdor, H Kocdor, JS Pereira, JE Vanegas, IH Russo, J Russo
    Clinical and Translational Oncology 15, 55-64 2013
    Citations: 24

  • Ghrelin expression of endometrium hyperplasia and endometrioid carcinoma
    AF Dagli, S Aydin, H Kocdor, B Gurates, İ Sahin, Z Catak, MR Ozercan, ...
    Gynecological Endocrinology 27 (3), 199-204 2011
    Citations: 20

  • Chemopreventive efficacies of rosiglitazone, fenretinide and their combination against rat mammary carcinogenesis
    H Kocdor, MA Kocdor, T Canda, D Gurel, R Cehreli, O Yilmaz, ...
    Clinical and Translational Oncology 11, 243-249 2009
    Citations: 18

  • Inhibition of cancer stem-like phenotype by curcumin and deguelin in CAL-62 anaplastic thyroid cancer cells
    MA Kocdor, H Cengiz, H Ates, H Kocdor
    Anti-Cancer Agents in Medicinal Chemistry-Anti-Cancer Agents) 19 (15), 1887-1898 2019
    Citations: 16

  • Serum tumor necrosis factor-, glutamate and lactate changes in two different stages of mechanical intestinal obstruction
    H Kodor, MA Kodor, H Astarcioğlu, M Fadiloğlu
    Turk J Gastroenterol 14 (2), 115-119 2003
    Citations: 13

  • A promising biomarker to distinguish benign and malignant renal tumors: ELABELA
    G Artas, T Kuloglu, AF Dagli, K Ugur, M Yardim, S Aydin, H Artas, ...
    Nigerian Journal of Clinical Practice 22 (3), 386-392 2019
    Citations: 12

  • The effects of vascular bed expansion in steatotic rat liver graft viability
    H Astarcioǧlu, S Karademir, K Atila, Saǧol, H Kodor, A oker, ...
    Transplant international 17 (4), 188-194 2004
    Citations: 7

  • Abstract# 2059: Mammary cancer prevention by short treatment with human chorionic gonadotropin
    J Vanegas, M Kocdor, J Pereira, H Kocdor, J Russo, K Snider, F Sheriff, ...
    Cancer Research 69 (9_Supplement), 2059-2059 2009
    Citations: 4

  • İskemi-Reperfzyon ve Kanser Metastazı: Biyokimyasal Bakış
    FC zkaya, H Kodor
    Dokuz Eyll niversitesi Tıp Fakltesi Dergisi 22 (2), 89-98 2008
    Citations: 4

  • The effects of parenteral glutamine on intestinal adaptation in a rat model of short bowel syndrome
    AD Ucar, H Kocdor, AE Canda, SM Unlu, R Cehreli, MA Kocdor
    Central European Journal of Medicine 5, 115-122 2010
    Citations: 3

  • The report of the 1st Turkey in vitro diagnostic symposium results
    H Kocdor, E Sezer, Z Erbayraktar, A Pabuccuoglu, T Onat, G Oktay, ...
    Turkish Journal of Biochemistry 42 (1), 97-100 2017
    Citations: 2