Rajat Goyal

Scopus Publications

Design, synthesis, in-vitro hydrolysis and biological evaluation of antioxidant conjugated mutual prodrugs of ibuprofen
Rajat Goyal, Prabodh Chander Sharma, Sumeet Gupta
Inflammopharmacology, 2026
Design, Synthesis, In Vitro Hydrolysis and Biological Evaluation of Antioxidant-Conjugated Mutual Prodrugs of Naproxen
Rajat Goyal, Sumeet Gupta, Prabodh Chander Sharma, Hitesh Chopra
Russian Journal of Bioorganic Chemistry, 2026
Objective: A novel series of antioxidant-conjugated mutual prodrugs of naproxen (RJ-01-01–RJ-01-10) was designed and synthesized to mitigate the gastrointestinal (GI) adverse effects associated with the parent drug, naproxen. Methods: The study included molecular docking, synthesis and characterization, in vitro hydrolysis, and biological evaluation. Results and Discussion: The synthesized prodrugs demonstrated high stability in simulated gastric fluid (SGF, pH 1.2), with minimal hydrolysis to the parent naproxen (18.62–24.14%), indicating reduced potential for gastric irritation. Conversely, in simulated intestinal fluid (SIF, pH 7.4), a significantly higher hydrolysis rate (75.07–84.01%) was observed, facilitating drug release and intestinal absorption. In docking studies, compounds RJ-01-04, RJ-01-05, RJ-01-06, RJ-01-08, and RJ-01-09 exhibited the highest binding energies (–13.68, –12.23, –13.74, –12.01, and –13.06 kcal/mol, respectively) compared to naproxen. During in vitro evaluation, RJ-01-04 showed significantly more potent COX-2 inhibition (IC50 = 44.18 ± 1.7 µM) than naproxen (IC50 = 61.48 ± 0.8 µM) and comparable COX-1 inhibition (IC50 = 55.34 ± 0.6 vs. 59.43 ± 0.5 µM for naproxen), indicating dual inhibitory activity. In AGS cells, RJ-01-04 reduced reactive oxygen species (ROS) levels and increased superoxide dismutase (SOD) activity more effectively than naproxen, demonstrating enhanced antioxidant effects. Western blot analysis confirmed downregulation of COX-2 and COX-1 protein expression in AGS cells treated with RJ-01-04. Cytotoxicity assessment (MTT assay) in HEK293 cells revealed that RJ-01-04 exhibited significantly lower cytotoxicity than naproxen. Conclusions: These findings support the mutual prodrug strategy as a promising approach to improve the therapeutic profile of naproxen through antioxidant conjugation.
Pathophysiology and Molecular Basis of Psoriasis
Kashish Wilson, Tanvi, Rajat Goyal, Sumeet Gupta, Chander Parkash Dora, Garima
Novel Carriers for Psoriasis Management and Pharmacotherapy, 2026
Psoriasis, a papulosquamous skin disease, is estimated to affect 2% of the global population. Traditionally believed to be a problem largely affecting keratinocytes in the epidermis, psoriasis has recently been identified as one of the most common immune-related diseases. Though this condition may manifest at any life stage, a dual distribution of age was observed, having a peak occurring between the ages of 20 and 30 as well as 50 and 60. Psoriasis possesses a complicated etiology that includes immunologic, hereditary, and systemic/local factors. Psoriasis shows an immense negative impact on human life quality, probably equivalent in comparison to coronary artery disease, type 2 diabetes, depressive disorders, and carcinoma, regardless of the fact that it usually possesses a minor influence on survival. The unregulated development of keratinocytes is the main constraint behind psoriasis, and improper regulation of the immune system serves as a pathophysiological factor. The pathogenesis generally includes the cooperation among several populations for immunocytes along with corresponding transmitting molecules that are: (1) innate immunocytes, which are mediated by antigenic-displaying cells, such as neutrophils, the cells of Langerhans, and natural-killing T lymphoid cells (2) acquired or adaptable immunocytes, which are facilitated by developed CD4+ and CD8+ T lymphocyte residing in the epidermis. The result of such immunological dysfunction leads to inflammation, which causes clinical lesions as well as histopathological inflammation, diagnostic of psoriasis development and perpetuation. The standard of lifestyle in patients has increased with biologic treatments, which focus on the cytokine-mediated pathophysiology of psoriasis. This book chapter will cover the molecular basis and primary pathophysiology of psoriasis.
Harnessing Nanoemulsions for Tailored Breast Cancer Therapy: Recent Insights and Opportunities
Sneep Kumar Chaturvedi, Gulshan Sharma, Sanskriti Saini, Sushma Jain, Karan Wadhwa, Rajat Goyal, Hardeep Singh Tuli, Rakesh Pahwa
Current Drug Research Reviews, 2026
Breast cancer is classified as the most prominent and aggressive form of cancer, predominantly affecting women worldwide, underscoring an imperative need for the development of innovative treatment strategies. Despite the vast array of treatment methods, including surgical removal, hormone therapy, gene therapy, radiation therapy, etc., these methods are primarily associated with significant drawbacks, such as a lack of site-specificity and multidrug resistance. In the pursuit of more effective breast cancer treatments, nanoemulsions emerge as an exceptionally promising alternative. Nanoemulsions represent an advanced drug delivery platform for a wide range of therapeutics, including chemotherapeutic agents, essential oils, herbal actives, and genetic material, offering innovative strategies for breast cancer management. Nanoemulsions offer distinct therapeutic advantages by enhancing solubility and bioavailability, increasing drug-loading efficiency, and enabling controlled, site-specific release of anticancer agents. They promote apoptosis, modulate multidrug resistance, and reduce systemic toxicity, thereby improving overall therapeutic efficacy. Furthermore, surface-functionalized nanoemulsions with targeting ligands markedly improve tumor selectivity, while localized delivery strategies, such as intraductal administration, prolong drug retention and minimize offtarget effects. This paper presents a comprehensive overview of breast cancer development and progression, emphasizing the therapeutic relevance of nanoemulsions. Although treating breast cancer with nanoemulsions holds extensive therapeutic promise, there remains considerable scope to reveal novel findings that can enhance their clinical applicability, thus offering promising avenues for further advancements.
Unlocking the Therapeutic Potential of Piperine - From Ethnopharmacology to Nanodelivery Strategies
Karan Wadhwa, Jasmine Sagwal, Rohil Panwar, Dolly Koli, Rakesh Pahwa, Rajat Goyal, Poonam Negi, Ravinder Verma
Current Nanomedicine, 2026
Herbs have long been esteemed for their therapeutic properties and utilized to treat a broad spectrum of diseases. Notably, piperine is a naturally occurring alkaloid abundantly found in numerous plants, with four isomeric variants. Contemporary literature has revealed that piperine has significant pharmacological activities, including cardioprotective, neuroprotective, gastroprotective, hepatoprotective, nephroprotective, anti-allergic, anti-cancer, antiinflammatory, anti-diabetic, anti-microbial, and many more. Piperine's diverse pharmacological profile not only reveals its versatility in experimental studies but also highlights its effectiveness in numerous clinical outcomes. However, despite the therapeutic benefits evident from numerous animal and human investigations, the clinical relevance of piperine faces numerous challenges because of its low aqueous solubility, stability, and limited bioavailability. To address these constraints, nanoformulations like nanoparticles, liposomes, micelles, gold nanogels, nanosuspensions, nanoemulsions, and self-nanoemulsifying drug delivery systems have emerged as innovative approaches that play a crucial role in optimizing the bioavailability and efficacy of piperine. By utilizing these novel drug delivery systems, piperine’s therapeutic potential can be harnessed, paving the way for its application in diverse clinical conditions. This manuscript seeks to advance the current understanding of piperine's therapeutic potential, elucidating its mechanistic insights against numerous disorders and exploring various nanoformulation strategies to optimize its delivery and efficacy.
Neuro-protective Potential of Honey: A Narrative Review
Sumel Ashique, Anas Islam, Prashant Kumar, Samy Selim, Soad K. Al Jaouni, Ananya Chakraborty, Ivan Kahwa, Rajat Goyal, Shivani Chopra, Hitesh Chopra
Current Pharmaceutical Design, 2026
Apitherapy, the therapeutic use of bee products, has attracted attention for its potential in treating various ailments. Honey is unique among bee products because it has a high concentration of medicinal chemicals. In recent years, there has been growing concern about exploring the neuroprotective features of honey. Our article aimed to consolidate existing research on the neuroprotective potential of honey, shedding more focus on its mechanisms of action and therapeutic properties. The literature suggests that honey exhibits neuroprotective properties by attenuating oxidative stress, alleviating neuroinflammation, and enhancing neuronal survival and regeneration. Especially, honey’s potential to mitigate neurodegenerative disorders and enhance cognitive function and memory. These reports position honey as a promising candidate for neuroprotection, offering a natural and accessible therapeutic option to combat neurological disorders. Its multifaceted mechanism of action makes it a valuable asset in neurotherapy. However, more research is warranted to clarify the specific compounds responsible for their neuroprotective effects and to optimize their therapeutic application. Unlocking the full potential of honey in neuroprotection could open the door to novel therapeutic approaches for the management of neurological conditions.
A Perspective Review on Animal Coronaviruses: From Infection Insights to Preventive Measures and Antiviral Advancements
Tanvi, Rajat Goyal, Rupesh K. Gautam, Kashish Wilson, Kajal Garg, Tanmay Sharma, Sumeet Gupta, Sachin Kumar Singh, Haider Ali, Gaurav Gupta, Md Sadique Hussain
Coronaviruses, 2026
Animal coronaviruses (CoVs) have emerged as significant pathogens with considerable implications for both animal and human health. This review provides an in-depth analysis of the origins, transmission dynamics, and pathogenic mechanisms of animal CoVs. We examine the viral entry, replication processes, and immune evasion strategies that enable CoVs to infect a variety of host species. Additionally, the review highlights recent advancements in prevention and therapeutic strategies, including the development of species-specific vaccines, enhanced biosecurity measures, and surveillance systems aimed at controlling zoonotic spillover. Furthermore, we discuss the latest antiviral strategies, including repurposed drugs, targeted molecular therapies, and the development of novel antiviral agents. This review emphasizes the importance of interdisciplinary research in advancing our understanding of animal CoVs and in developing effective interventions to mitigate their impact on global health.
New insights on pharmacological potential of montelukast: a comprehensive review
Karan Goel, Dhirendra Singh, Rajat Goyal, Seema Bansal, Sukhbir Singh, Neelam Sharma, Sumeet Gupta
Inflammopharmacology, 2025
Insights on Natural Products and Their Derivatives in Tuberculosis Management
Rajat Goyal, Kumar Susheel, Kajal Garg, Rani Neha, Hitesh Chopra, Kashish Wilson, Sumeet Gupta
Scripta Medica Banja Luka, 2025
Tuberculosis (TB), a bacterial disease primarily affecting middleas well as low-income countries, poses a significant public health threat. Natural products have historically been and remain a vital source of fresh medications for treating various diseases. The renewed interest in natural product research is partly a result of the increasing prevalence of drug-resistant Mycobacterium tuberculosis (MTb) strains along with adverse outcomes associated with firstand second-line anti-tubercular drugs. The TB complexity and the complications arising from the use of allopathic medications, such as multidrug resistance, highlight the effectiveness of natural medications in this context. Therefore, it is crucial to explore new treatment therapies to effectively mitigate the harmful effects associated with TB. More research is needed on various natural substances, both independently and in combination with currently approved drug regimens, as potential TB treatment options.
Insights on prospects of natural products in the management of autism
Rajat Goyal, Namish Manchanda, Rupesh K. Gautam
Empowering Innovations in Advanced Autism Research and Management, 2025
Autism spectrum disorder (ASD) is a multifaceted neurological condition that impedes an individual's capacity for communication and socialization for the rest life. Recurrent, capped behaviours which compromise cognitive function are indeed its hallmark. To treat behavioural issues linked to autism, speech therapy, occupational therapy, and special education programs have all been employed. The researchers also looked at using herbal remedies to treat autistic people because of the negative effects of ASD medications. Natural products have proven to be a viable treatment for a number of illnesses, including autism and other neurological problems. These naturally existing chemicals that are known to be likely candidates for psychotherapy may be employed as chemical models or templates for building novel materials that could be a remedy for autism. In this study, we discuss the physiological and epidemiological features of autism and the role of natural products in the treatment of autism.
Insights of perspectives of autism spectrum disorder
Sapna Sirswal, Rajat Goyal, Karan Goel, Manisha, Rupesh K. Gautam, Sumeet Gupta
Empowering Innovations in Advanced Autism Research and Management, 2025
Phytochemical, Ethnobotanical, and Global Perspectives of Genus Echinacea: A Panoramic Review
Disha Arora, Smriti Parashar, Rupesh K. Gautam, Rajat Goyal
Current Traditional Medicine, 2025
Advancements and Applications of Herbal Cocrystals
Rajat Goyal, Pankaj Popli, Kashish Wilson, Hitesh Chopra, Sonia Dhiman, Sumeet Gupta
Cocrystals in Pharmaceutical Sciences Design to Applications, 2025
Nanomaterial-Based Vaccine Adjuvants
Tanvi, Philips Kumar, Rajat Goyal, Kashish Wilson, Hitesh Chopra, Rajeev K. Singla
Emerging Pathways of Vaccine Adjuvants A Nonspecific Stimulant of the Immune System, 2025
Green Synthesis of Copper Oxide Nanoparticles by Hydroethanolic Extract of Rubus ellipticus: Antimicrobial and Antidiabetic Activities
Anjana Kumari, Lokender Kashyap, Vinit Prakash, Rupesh K. Gautam, Rajat Goyal, Vikas Chauhan
Current Nanomedicine, 2025
Overview of Monkeypox Virus
Kashish Wilson, G Garima, Rajat Goyal, Hitesh Chopra, Shivani Chopra, Meenakshi Dhanawat
Scripta Medica Banja Luka, 2025
Re-evaluating the Relationship between Cosmetic Products and Cancer: An Investigative Review of Paradigms
Philips Kumar, Prantik Kishor Chakroborty, Kashish Wilson, Rajat Goyal, Sumeet Gupta, Anjali Saharan, Nidhi Rani, Prerna Sharma
Current Cancer Therapy Reviews, 2025
Nano Selenium: A Promising Solution for Infectious Diseases - Current Status and Future Prospects
Shaheen Husain, Rania Mohammad Sabri Sultan, Kirti Saxena, Fareha Bano, Rajat Goyal, Shivani Chopra, Hitesh Chopra, Suresh K. Verma
Current Pharmaceutical Design, 2025
Neural Networks of Knowledge: Ontologies Pioneering Precision Medicine in Neurodegenerative Diseases
Pooja Mittal, Rupesh Kumar Gautam, Himanshu Sharma, Rajat Goyal, Garima Malik, Ramit Kapoor, Dileep Kumar Sharma, Mohammad Amjad Kamal, Haque Shafiul, Siva Gajula Nageswara Rao
Current Neuropharmacology, 2025
Decoding and Unravelling Mpox, Herpes, and Syphilis Infections: A State of Art Review
Jiao Wang, Rajat Goyal, Rupesh K. Gautam, Kajal Garg, Shaheen Husain, Hitesh Chopra, Ankit Kumar Dubey, Rehab A. Rayan, Mohammad Amjad Kamal, Dinesh Kumar Mishra, Rohit Gundamaraju, Bairong Shen, Rajeev K. Singla
Current Pharmaceutical Biotechnology, 2025
Exploring the pharmacokinetics, drug-likeness, and toxicological features of anticancer flavonoids: a Boulevard to explore their clinical translational potential
Ankit Kumar Dubey, Siva Sai Chandragiri, Abin V. Geevarghese, Bhupinder Kapoor, Monica Gulati, Pooja Rani, Gursharan Singh, Vivek P. Chavda, Rohit Gundamaraju, Himangini Bansal, Rupesh K. Gautam, Rajat Goyal, Michael P. Okoh, Bairong Shen, Rajeev K. Singla
Frontiers in Pharmacology, 2025
Health-promoting and medicinal properties of Zingiberaceae family plants: A minireview with a special focus on galangal, turmeric, cardamom, and ginger
Maima Matin, Rajeev K. Singla, Artur Jóźwik, Jarosław Olav Horbańczuk, Natalia Ksepka, Kamil Wysocki, Thadiyan Parambil Ijinu, Neenthamadathil Mohandas Krishnakumar, Sreejith Pongillyathundiyil Sasidharan, Ifeoma C. Ezenyi, John Igoli, Fabio Fusi, Sara Frazzini, Luciana Rossi, Michel-Edwar Mickael, Abhishek Joshi, Olga Adamska, Artur Stolarczyk, Esra Capanoglu, Deniz Gunal-Koroglu, Shi-Hui Cheng, Omar M. Atrooz, Kiran Kharat, Ibrahim M. Abu-Reidah, Neeraj Rani, Atul Kabra, Ruchika Kabra, Dama Sreedhar Preethidan, Prathyusha Surendran, Emad Mohamed Abdallah, Seetha Harilal, Rajesh Kumar, Syed Abidullah, Hemanth Kumar Boyina, Vimal Arora, Prasanna Srinivasan Ramalingam, Sujatha Elangovan, Sivakumar Arumugam, Tanveer Alam, Edlira Aruci, Elena González-Burgos, Isabel Ureña-Vacas, Visitación López-Miranda, Esperanza Herradón, Rupesh Kumar Gautam, Rajat Goyal, Shah Alam Khan, Logesh Rajan, Joel Ojogbane Onoja, Sharad Vats, Akinleye Akinrinde, Smith B. Babiaka, Conrad V. Simoben, Doris E. Enow, Kennedy O. Abuga, Priti Talwar, Palaniyandi Ravanan, Reda El Boukhari, Ahmed Fatimi, Fabien Schultz, Ren-You Gan, Jean Noël Nyemb, Gaetan Bayiha Ba Njock, Constant Anatole Pieme, Goh Bey Hing, Ricardo Lagoa, Nikolay T. Tzvetkov, Farhan Bin Matin, Antonello Santini, Jaya Arora, Aswathy Chankaramkandath Vasu, Suraj Kadunganattil, Abeer Essam Noman, Luay M Alsubhi, Indra Lasmana Tarigan, Shafaat Yar Khan, Ali Zarrabi, Hefa Mangzira Kemung, Kavitha Raj Varadaraju, Tomasz M. Karpiński, Md. Mohaiminul Islam, Shaikh Jamal Uddin, Carmela Fimognari, Hari Prasad Devkota, Ivana Carev, Dongdong Wang, Kenneth Anchang Yongabi, Luther Bob Mbeku, Sohini Chakraborty, Sourav S. Patnaik, Shanmugam Thangapandiyan, Bikash Baral, Siva Sai Chandragiri, Eliana B. Souto, Gérard Lizard, Fatiha Brahmi, Farid Khallouki, Adil El Midaoui, Ronan Lordan, Anupam Bishayee, Meng-Yao Li, Monika Szymańska-Czerwińska, Krzysztof Niemczuk, Manik Chandra Shill, Michał Ławiński, Oleh Lushchak, Iwona Wojtasik-Kalinowska, Agnieszka Wierzbicka, Thomas Jakschitz, Mathew Dan, Imen Ghzaiel, Leila Rezig, Anne Vejux, Amira Zarrouk, Ahmad Ali, Andy Wai Kan Yeung, Günther K. Bonn, Bairong Shen, Atanas G. Atanasov
Current Research in Biotechnology, 2025
Insights on therapeutic approaches of natural anti-Alzheimer's agents in the management of Alzheimer's disease: A future perspective
Kalpesh Mahajan, Sanjay Sharma, Rupesh K Gautam, Rajat Goyal, Dinesh Kumar Mishra, Rajeev K Singla
Journal of Alzheimer S Disease, 2024
Therapeutic effect of targeted antioxidant natural products
Sohini Mukherjee, Hitesh Chopra, Rajat Goyal, Sihao Jin, Zhenzhen Dong, Tanmoy Das, Tanima Bhattacharya
Discover Nano, 2024
Harnessing nanotechnology for enhanced delivery of erlotinib: a dynamic duo in cancer treatment
Rakesh Pahwa, Swati Saini, Jatin Chhabra, Rajat Goyal, Shobhit Kumar, Rajendra Awasthi, Harish Dureja
Beni Suef University Journal of Basic and Applied Sciences, 2024
Natural products in the management of neurodegenerative diseases
Rajat Goyal, Pooja Mittal, Rupesh K. Gautam, Mohammad Amjad Kamal, Asma Perveen, Vandana Garg, Athanasios Alexiou, Muhammad Saboor, Shafiul Haque, Aisha Farhana, Marios Papadakis, Ghulam Md Ashraf
Nutrition and Metabolism, 2024
Stem cell transplantation therapy for advanced liver damage-associated neurodegenerative disorders
Anjna Sharma, Ameya Sharma, Divya Dheer, Raghu Rai Sharma, Vivek Puri, Shabana Bibi, Amina Shamas, Sameeullah Memon, Rajat Goyal, Priyanka, Hitesh Chopra
International Journal of Surgery, 2024
Insights on Effective Complementary Strategies in the Management of Urinary Tract Infections
Shweta Gandhi, Priya Shah, Rajat Goyal, Rupesh Gautam, Hitesh Chopra
Scripta Medica Banja Luka, 2024
Innovative Approaches for Onychomycosis Treatment: An Insight Into Natural Remedies and Novel Pharmaceutical Formulations
Hitesh Chopra, Kavita Munjal, Rajat Goyal, Kashish Wilson, Kuldeep Dhama
Scripta Medica Banja Luka, 2024
PREPARATION AND CHARACTERIZATION OF MICROSPHERES UTILIZING RATE-CONTROLLING MEMBRANES FOR THE MANAGEMENT OF DIABETES MELLITUS
, Nitu Patidar, Nadeem A. Farooqui, Darshan Jamindar, , Dinesh K. Mishra, , Rajat Goyal, , Hitesh Chopra,, Rupesh K. Gautam
Indian Drugs, 2024
Insights into Prospects of Novel NSAID Prodrugs in the Management of Gastrointestinal Toxicity: A Perspective Review
Rajat Goyal, Sumeet Gupta, Prabodh Sharma, Manu Sharma
Recent Advances in Inflammation and Allergy Drug Discovery, 2024
Biomedical Applications of Alginates
Payal Kesharwani, Swapnil Sharma, Vishal Chaudhary, Rajat Goyal, Rupesh K. Gautam
Biopolymers for Biomedical Applications, 2024
Insights on the Emerging Therapeutic Potential of Terpenoids as Anti-inflammatory Agents: A Scoping Review
Mohini Devi, Prabhjeet Kaur Bamrah, Rajat Goyal, Manjusha Choudhary, Hitesh Chopra
Journal of Bio X Research, 2024
Insights from a Brief Study of Renal Calculi: Recent Diagnostic and Treatment Approaches
Aashish Kumar, Rajat Goyal, Kajal Garg, Sumeet Gupta, Kashish Wilson, Hitesh Chopra
Journal of Bio X Research, 2024
Synbiotics: Complementary and Synergistic Approach Against Different Carcinomas
Jatin Chhabra, Karan Wadhwa, Rajat Goyal, Neha Rao, Harish Dureja, Rakesh Pahwa
Synbiotics in Human Health Biology to Drug Delivery, 2024
Insights on aspects of apoptosis in neurodegenerative disorders: a comprehensive review
Rajat Goyal, Kashish Wilson, Anjali Saharan, Rupesh K. Gautam, Hitesh Chopra, Sumeet Gupta, Mohammad Amjad Kamal
Exploration of Medicine, 2024
Nanomedicine: Innovative Strategies and Recent Advances in Targeted Cancer Therapy
Rupesh K. Gautam, Pooja Mittal, Rajat Goyal, Kamal Dua, Dinesh Kumar Mishra, Sanjay Sharma, Rajeev Kumar Singla
Current Medicinal Chemistry, 2024
Insights on Quercetin Therapeutic Potential for Neurodegenerative Diseases and its Nano-technological Perspectives
Rajat Goyal, Garima Mittal, Suman Khurana, Neelam Malik, Vivek Kumar, Arti Soni, Hitesh Chopra, Mohammad Amjad Kamal
Current Pharmaceutical Biotechnology, 2024
Mechanism-based Suppression of Cancer by Targeting DNA-Replicating Enzymes
Preeti Arya, Hitesh Malhotra, Benu Chaudhary, Amrit Sarwara, Rajat Goyal, Chunpeng Wan, Dinesh Kumar Mishra, Rupesh Kumar Gautam
Current Protein and Peptide Science, 2024
Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier
KARAN WADHWA, PAYAL CHAUHAN, SHOBHIT KUMAR, RAKESH PAHWA, RAVINDER VERMA, RAJAT GOYAL, GOVIND SINGH, ARCHANA SHARMA, NEHA RAO, DEEPAK KAUSHIK
Oncology Research, 2024
Identification and evaluation of antimicrobial and anti-arthritis activities of hydroethanolic extract of Rubus ellipticus leaves
Anjana Kumari, Vinit Prakash, Dinesh Gupta, Lokender Kashyap, Rajat Goyal, et al.
Narra J, 2023
Celiac disease: Pathogenesis, disease management and new insights into the herbal-based treatments
Pooja Mittal, Disha Arora, Smriti Parashar, Rajat Goyal, Amir Khan, et al.
Narra J, 2023
A retrospective study on the impact of high-fat diets on human health related to metabolic associated diseases
Everything You Need to Know about High Fat Diets, 2023
Therapeutic Benefits of Miracle Tree Moringa oleifera: A Complete Overview
Faridi Shabnam, Isha Rani, Dhiman Vivek, Rajat Goyal, Rupesh Kumar Gautam
Current Traditional Medicine, 2023
Fullerenes for Anticancer Drug Delivery
Manu Sharma, Rajat Goyal
Nanoparticles in Diagnosis Drug Delivery and Nanotherapeutics, 2023
Artificial intelligence (AI) and machine learning in the treatment of various diseases
Pooja Mittal, Rajat Goyal, Ramit Kapoor, Rupesh Kumar Gautam
Computational Approaches in Drug Discovery Development and Systems Pharmacology, 2023
Recent Advancement of Nanotherapeutics to Treat Breast Cancer
Devesh U. Kapoor, Rajat Goyal, Rajiv R. Kukkar, Rupesh K. Gautam
Drug and Therapy Development for Triple Negative Breast Cancer, 2023
Insights into the prospects of green chemistry and nanotechnology in environmental sustainability
Rajat Goyal, Mohini Devi, Rupesh Kumar Gautam, Sumeet Gupta
Role of Green Chemistry in Ecosystem Restoration to Achieve Environmental Sustainability, 2023
Edible Mushroom assisted synthesis and applications of metal nanoparticles: A comprehensive review
Journal of Integrated Science and Technology, 2023
Natural Products-based Drugs: Potential Drug Targets Against Neurological Degeneration
Chunpeng Wan, Rupesh K. Gautam, Pooja Mittal, Rajat Goyal, Ramit Kapoor
Current Neuropharmacology, 2023
Repurposing of Drugs for the Treatment of Microbial Diseases
Kushal Kumar Bansal, Rajat Goyal, Archana Sharma, Prabodh Chander Sharma, Ramesh K. Goyal
Drug Repurposing for Emerging Infectious Diseases and Cancer, 2023
Biobased materials in nutraceuticals
Rajat Goyal, Shruti Aggarwal, Vipin Saini, Rupesh K. Gautam, Shakeel Ahmed
Advanced Applications of Biobased Materials Food Biomedical and Environmental Applications, 2023
An Insight View on the Role of Herbal Medicines in Infectious Diseases
Rupesh K. Gautam, Smriti Parashar, Rajat Goyal, Sanjay Sharma, Sumeet Gupta, Pooja Mittal
Current Traditional Medicine, 2023
Synbiotics in Colon Cancer
Hitesh Chopra, Rajat Goyal, Atif Amin Baig, Sonia Arora, Kamal Dua, Rupesh K. Gautam
Synbiotics for the Management of Cancer, 2023
Recent advancements in skin cancer treatment: a critical review
Rajat Goyal, Shaheen Husain, Kashish Wilson, Hitesh Chopra, Rakesh Pahwa, Mathumalar Loganathan, Rohit Sharma
Exploration of Medicine, 2023
Natural products derived from medicinal plants and microbes might act as a game-changer in breast cancer: a comprehensive review of preclinical and clinical studies
Rajeev K. Singla, Xiaoyan Wang, Rohit Gundamaraju, Shikha Joon, Christos Tsagkaris, Sahar Behzad, Johra Khan, Rupesh Gautam, Rajat Goyal, Jaruporn Rakmai, Ankit Kumar Dubey, Jesus Simal-Gandara, Bairong Shen
Critical Reviews in Food Science and Nutrition, 2023
Medicalization of sexuality and sexual health: A perspective review
Rajat Goyal, Deepak Chandran, Kajal Garg, Pran Mohankumar, Sumeet Gupta, Rupesh K. Gautam, Hitesh Chopra, Kuldeep Dhama
Journal of Experimental Biology and Agricultural Sciences, 2022
The role of nanomaterials in enhancing natural product translational potential and modulating endoplasmic reticulum stress in the treatment of ovarian cancer
Rajeev K. Singla, Pooja Sharma, Dinesh Kumar, Rupesh K. Gautam, Rajat Goyal, Christos Tsagkaris, Ankit Kumar Dubey, Himangini Bansal, Rohit Sharma, Bairong Shen
Frontiers in Pharmacology, 2022
Natural products for the treatment of endocrine and metabolic disorders
Natural Products for Treatment of Metabolic Syndrome, 2022
Insights on prospects of nano-siRNA based approaches in treatment of Cancer
Rajat Goyal, Hitesh Chopra, Inderbir singh, Kamal Dua, Rupesh K. Gautam
Frontiers in Pharmacology, 2022
Recent advancement of nanotechnology in functional foods: Applications perspectives
Abhishek Kanugo, Rajat Goyal, Sanjay Sharma, Rupesh Kumar Gautam
Nanotechnology in Functional Foods, 2022
Chemopreventive Potential of Dietary Nanonutraceuticals for Prostate Cancer: An Extensive Review
Hitesh Chopra, Shabana Bibi, Rajat Goyal, Rupesh K. Gautam, Rashmi Trivedi, Tarun Kumar Upadhyay, Mohd Hasan Mujahid, Mohammad Ajmal Shah, Muhammad Haris, Kartik Bhairu Khot, Gopika Gopan, Inderbir Singh, Jin Kyu Kim, Jobin Jose, Mohamed M. Abdel-Daim, Fahad A. Alhumaydhi, Talha Bin Emran, Bonglee Kim
Frontiers in Oncology, 2022
Pyrazole based Furanone Hybrids as Novel Antimalarial: A Combined Experimental, Pharmacological and Computational Study
Deepika Choudhary, Isha Rani, Jyoti Monga, Rajat Goyal, Asif Husain, Prabha Garg, Sukhbir Lal Khokra
Central Nervous System Agents in Medicinal Chemistry, 2022
Thiazolopyrimidines: A Retrospective Study of Synthesis, Structure-Activity Relationship and Diverse Pharmacological Actions
S. AGGARWAL, M. DEVGUN, R. NARANG, S. LAL, A.C. RANA, R. GOYAL
Asian Journal of Chemistry, 2022
Natural Kinase Inhibitors for the Treatment and Management of Endometrial/Uterine Cancer: Preclinical to Clinical Studies
Rajeev K. Singla, Sahar Behzad, Johra Khan, Christos Tsagkaris, Rupesh K. Gautam, Rajat Goyal, Hitesh Chopra, Bairong Shen
Frontiers in Pharmacology, 2022
Use of Nano-Nutraceuticals as Anti-Inflammatory Tools in Cardiovascular Disease
Rajat Goyal, Anjali Saharan, Rupesh K. Gautam
Handbook of Nanotechnology in Nutraceuticals, 2022
COMPARATIVE HIGHLIGHTS ON MERS-COV, SARS-COV-1, SARS-COV-2, AND NEO-COV
R. Goyal, R. Gautam, Hitesh Chopra, Ankit Kumar Dubey, Rajeev K. Singla, R. Rayan, M. Kamal
Excli Journal, 2022
Natural Products for the Management of Castration-Resistant Prostate Cancer: Special Focus on Nanoparticles Based Studies
Rajeev K. Singla, Chandragiri Siva Sai, Hitesh Chopra, Sahar Behzad, Himangini Bansal, Rajat Goyal, Rupesh K. Gautam, Christos Tsagkaris, Shikha Joon, Shailja Singla, Bairong Shen
Frontiers in Cell and Developmental Biology, 2021
Green chemistry approaches for thiazole containing compounds as a potential scaffold for cancer therapy
Diksha Sharma, Vishal Sharma, Archana Sharma, Rajat Goyal, Rajiv K. Tonk, Vijay Kumar Thakur, Prabodh C. Sharma
Sustainable Chemistry and Pharmacy, 2021
Green chemistry approaches towards the design and synthesis of anti-infective fluoroquinolone derivatives
Rajat Goyal, Archana Sharma, Vijay Kumar Thakur, Monika Ola, Prabodh Chander Sharma
Current Research in Green and Sustainable Chemistry, 2021
Hydrazone comprising compounds as promising anti-infective agents: chemistry and structure-property relationship
P.C. Sharma, D. Sharma, A. Sharma, N. Saini, R. Goyal, M. Ola, R. Chawla, V.K. Thakur
Materials Today Chemistry, 2020
Insights on fluoroquinolones in cancer therapy: chemistry and recent developments
P.C. Sharma, R. Goyal, A. Sharma, D. Sharma, N. Saini, H. Rajak, S. Sharma, V.K. Thakur
Materials Today Chemistry, 2020

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