Artificial intelligence, complex network, medical images, foodome
195
Scopus Publications
6828
Scholar Citations
43
Scholar h-index
130
Scholar i10-index
Scopus Publications
From networks of data to networks of care in clinical medicine: this is not artificial intelligence Pierfrancesco Novielli, Roberto Bellotti, Mohamad Khalil, Piero Portincasa, Sabina Tangaro European Journal of Internal Medicine, 2026 The increasing availability of clinical, omic, and imaging data in clinical medicine opens unprecedented opportunities to uncover hidden patterns and mechanistic insights into disease. Available tools augment clinical reasoning, equipping clinicians with new layers of understanding to support personalized treatment and transparent risk assessment. More tools are being implemented and will soon enter such a challenging field of study and application. Graph- and sequence-based Artificial Intelligence (AI) operating on these networks underpins the vision of precision medicine, enabling early diagnosis, disease staging, treatment selection, and transparent risk stratification. Crucially, eXplainable AI (XAI) methods attribute predictions to specific nodes and sub-networks (e.g., genes, proteins, metabolites, microbes, clinical features), aligning model outputs with clinical reasoning and regulatory expectations. Rather than replacing clinicians, these tools augment clinical attentiveness and insight by tailoring decisions to each patient's molecular and clinical profile. By modelling complexity in an interpretable way, AI and network science convert performance into practice. Internists must be prepared to face this rapidly growing technological challenge. Here, we explore how network-based modelling and XAI can enhance clinical reasoning by revealing emergent behaviors, stratification patterns, and novel interactions across biological systems.
Explainable AI-Based Hyperspectral Classification Reveals Differences in Spectral Response over Phenological Stages Rameez Ahsen, Pierpaolo Di Bitonto, Pierfrancesco Novielli, Michele Magarelli, Donato Romano, Martina Di Venosa, Anna Maria Stellacci, Nicola Amoroso, Alfonso Monaco, Bruno Basso, Roberto Bellotti, Sabina Tangaro Biology, 2026 Optimizing nitrogen (N) fertilization is essential for sustaining durum wheat yield and grain quality while reducing the environmental impacts associated with N over-application. Hyperspectral sensing provides a rapid and non-destructive approach for monitoring crop N status. However, high-dimensional data, phenology-dependent spectral responses, and spatial autocorrelation in field measurements limit robust nitrogen classification and interpretation. This study evaluated hyperspectral-based nitrogen status classification in durum wheat under Mediterranean field conditions and identified key spectral regions using explainable artificial intelligence. A field experiment was conducted in Southern Italy using ten N fertilization rates (0–180 kg N ha−1). Canopy reflectance was acquired at the booting and heading stages from georeferenced sampling locations. Three nitrogen stratification strategies (binary Low–High, Extreme, and three-level) were evaluated using Random Forest, SVM-RBF, and XGBoost classifiers. Model performance was assessed using spatially independent Leave-One-Plot-Out cross-validation at both the sample and plot levels, with plot-level predictions derived through majority voting. Classification robustness was strongly influenced by the stratification strategy and phenological stage. The binary Low–High stratification achieved the highest sample-level accuracy, with a maximum of 0.78 at booting (SVM-RBF) and 0.75 at heading (SVM-RBF), whereas the Extreme stratification produced intermediate performance, with maximum accuracies of 0.73 at booting (SVM-RBF) and 0.63 at heading (XGBoost). Plot-level aggregation improved performance, reaching up to 0.90 at booting and 1.00 at heading. SHAP analysis highlighted red, red-edge, and near-infrared wavelengths as the dominant contributors, with increased reliance on longer wavelengths at the heading. Overall, explainable machine learning provides a robust framework for hyperspectral nitrogen monitoring in durum wheat.
High-Resolution NO2, O3, and PMs Estimation in Puglia: Leveraging AI and Explainability Techniques Alessandro Fania, Giovanni Lorusso, Roberto Cilli, Nicola Amoroso, Maria Adamo, Mariella Aquilino, Loredana Bellantuono, Marica De Lucia, Antonio Lacalamita, Marianna La Rocca, Tommaso Maggipinto, Angela Morabito, Alessandra Nocioni, Ester Pantaleo, Roberto Primerano, Sabina Tangaro, Roberto Bellotti, Alfonso Monaco Atmosphere, 2026 Air pollution remains a major environmental challenge, with severe impacts on human health and ecosystems. Recent advances in satellite technology have transformed air quality monitoring by enabling global, continuous observations of atmospheric pollutants. However, satellite data often lack the precision of ground-based stations. This study aims to develop a machine learning model to predict daily surface concentrations of key air pollutants (NO2, O3, PM10, and PM2.5) at high spatial resolution (300 m) in the Apulia region. Using Regional Environmental Protection Agency (ARPA) station data from 2019 to 2022 and meteorological, geographic, land-use, and temporal variables, we trained an XGBoost model on a 300 m grid. Model performance, assessed by repeated cross-validation, showed an average R2 of 0.71, with values of 0.77 for NO2, 0.78 for O3, 0.67 for PM2.5, and 0.64 for PM10. eXplainable AI (XAI) methods confirmed strong alignment with established scientific knowledge, enhancing model reliability and offering insights into pollutant distribution drivers.
Exponential random graph-based eXplainable Artificial Intelligence for Alzheimer disease Nicola Amoroso, Ester Pantaleo, Marianna La Rocca, Loredana Bellantuono, Saverio Pascazio, Sabina Tangaro, Alfonso Monaco, Roberto Bellotti Physical Review E, 2026 The use of statistical physics models to investigate real-world networks and reveal their underlying dynamics has shown promising results and acquired increasing attention. Here, we show how exponential random-graph (ERG) models can be suitably adopted to characterize how Alzheimer's disease (AD) affects brain connectivity. Magnetic-resonance imaging (MRI) of the brain was used to define a brain connectivity network whose nodes are the different brain regions, and the links indicate the pairwise structural relationships. Based on T1-weighted MRI brain scans of 126 normal controls (NC) and 92 AD patients, ERGs were able to outline both “global” and “local” disease patterns. Our findings demonstrate that ERGs accurately highlight how AD affects brain connectivity reaching an overall classification accuracy of 0.82 ± 0.08 . Besides, ERGs outline which regions of the brain are the most affected by the disease, thus proving to be a formidable instrument also to investigate the disease pathological mechanisms; more importantly, as these effects are evaluated at patient level, they can be exploited to design innovative diagnosis support systems or to provide a novel explainable framework for decision support systems. Finally, thanks to its generality, the approach proposed in this study paves the way for further applications and investigations inquiring into the use of ERGs for other diseases and different data sources or the use of alternative models.
Personalized colorectal cancer risk assessment through explainable AI and Gut microbiome profiling Pierfrancesco Novielli, Simone Baldi, Donato Romano, Michele Magarelli, Domenico Diacono, Pierpaolo Di Bitonto, Giulia Nannini, Leandro Di Gloria, Roberto Bellotti, Amedeo Amedei, Sabina Tangaro Gut Microbes, 2025 The clinical adenoma – carcinoma progression represents a well-established framework for understanding colorectal cancer (CRC) development, although the molecular mechanisms underlying this transition remain only partially understood. Increasing evidence suggests the gut microbiome (GM) as a key modulator of colorectal carcinogenesis, positioning microbial profiling as a promising avenue for noninvasive risk stratification and early detection. In this study, Machine Learning (ML) classifiers integrated with eXplainable Artificial Intelligence (XAI) techniques were employed to identify microbiome-derived biomarkers predictive of CRC and adenomatous lesions. The models were trained on 16S rRNA sequencing data from 453 patients and evaluated through cross-validation, achieving AU-ROC and AU-PRC scores of 0.71 and 0.67, respectively. External validation on an independent Italian cohort (n=43) yielded AU-ROC and AU-PRC scores of 0.70 and 0.89, respectively. XAI-based interpretation revealed consistent microbial signatures across datasets. In detail, taxa belonging to the Fusobacterium and Peptostreptococcus genera were associated with increased CRC risk, whereas the Eubacterium eligens group was identified as a robust negative predictor. Beyond classification, patient-level explanations enabled by XAI facilitated the identification of adenoma subgroups exhibiting microbiome profiles converging toward those of CRC, suggesting the presence of transitional microbial states. Moreover, SHAP-based interaction networks uncovered microbial hubs and inter-species dependencies characterizing high-risk configurations, providing insights into the ecological dynamics of colorectal tumorigenesis. These findings demonstrate the added XAI value in elucidating microbiome interactions, enhancing model interpretability, and supporting biologically informed hypotheses. This integrative, explainable framework highlights the potential of AI-driven microbiome analysis in precision oncology and advances the development of interpretable, noninvasive tools for CRC risk prediction and management.
Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research Jonathan L. Golob, Tomiko T. Oskotsky, Alice S. Tang, Alennie Roldan, Verena Chung, Connie W.Y. Ha, Ronald J. Wong, Kaitlin J. Flynn, Rong Chai, Claire Dubin, Antonio Parraga-Leo, Camilla Wibrand, Samuel S. Minot, Boris Oskotsky, Gaia Andreoletti, Idit Kosti, Julie Bletz, Amber Nelson, Jifan Gao, Zhoujingpeng Wei, Guanhua Chen, Zheng-Zheng Tang, Pierfrancesco Novielli, Donato Romano, Ester Pantaleo, Nicola Amoroso, Alfonso Monaco, Mirco Vacca, Maria De Angelis, Roberto Bellotti, Sabina Tangaro, Zehua Wang, Jiaming Yao, Akhil Goel, Jiangyue Mao, Huiqian Wang, Yuci Zhang, Ambuj Tewari, Abigail Kuntzleman, Isaac Bigcraft, Stephen Techtmann, Daehun Bae, Eunyoung Kim, Jongbum Jeon, Soobok Joe, Kevin R. Theis, Sherrianne Ng, Yun S. Lee, Patricia Diaz-Gimeno, Phillip R. Bennett, David A. MacIntyre, Gustavo Stolovitzky, Susan V. Lynch, Jake Albrecht, Nardhy Gomez-Lopez, Roberto Romero, David K. Stevenson, Nima Aghaeepour, Adi L. Tarca, James C. Costello, Marina Sirota Cell Reports Medicine, 2025
Leveraging Explainable Artificial Intelligence for Genotype-to-Phenotype Prediction: A Case Study in Arabidopsis thaliana Pierfrancesco Novielli, Nelson Nazzicari, Stefano Pavan, Chiara Delvento, Domenico Diacono, Claudia Zoani, Roberto Bellotti, Sabina Tangaro Applied System Innovation, 2025 Predicting phenotypes from genomic data can significantly advance agriculture. Genomic selection, which uses genome-wide DNA markers to identify individuals with high genetic value, enhances the accuracy of breeding programs. While linear models are routinely used for genomic selection (GS), machine learning (ML) models offer complementary potential. In this study, robust ML-based models were developed to predict five phenotypic traits—three related to flowering time and two to leaf number—in Arabidopsis thaliana, a model plant with a fully sequenced genome. Using explainable artificial intelligence (XAI), specifically SHapley Additive exPlanations (SHAP) values, we identified SNPs that contributed most to trait prediction. Many of these SNPs were located in or near genes known to regulate flowering and stem elongation, such as DOG1 and VIN3, supporting the biological plausibility of the model. SHAP also enabled local interpretability at the single-plant level, revealing the genotypic basis of individual predictions. Our results indicate that integrating ML with XAI improves model interpretability and provides predictive performance comparable to traditional methods. This approach confirms known genotype–phenotype relationships and highlights new candidate loci, paving the way for functional validation. The proposed methodology offers promising applications in precision breeding and translation of insights from Arabidopsis to crop species.
Data-Driven Innovations in Food Safety: The Role of AI and Big Data in METROFOOD-IT Michele Magarelli, Pierpaolo Di Bitonto, Donato Romano, Pierfrancesco Novielli, Rameez Ahsen, Claudia Zoani, Roberto Bellotti, Sabina Tangaro 2025 IEEE International Workshop on Metrology for Industry 4 0 and Iot Metroind4 0 and Iot 2025 Proceedings, 2025
Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research Jonathan L. Golob, Tomiko T. Oskotsky, Alice S. Tang, Alennie Roldan, Verena Chung, Connie W.Y. Ha, Ronald J. Wong, Kaitlin J. Flynn, Antonio Parraga-Leo, Camilla Wibrand, Samuel S. Minot, Boris Oskotsky, Gaia Andreoletti, Idit Kosti, Julie Bletz, Amber Nelson, Jifan Gao, Zhoujingpeng Wei, Guanhua Chen, Zheng-Zheng Tang, Pierfrancesco Novielli, Donato Romano, Ester Pantaleo, Nicola Amoroso, Alfonso Monaco, Mirco Vacca, Maria De Angelis, Roberto Bellotti, Sabina Tangaro, Abigail Kuntzleman, Isaac Bigcraft, Stephen Techtmann, Daehun Bae, Eunyoung Kim, Jongbum Jeon, Soobok Joe, Kevin R. Theis, Sherrianne Ng, Yun S. Lee, Patricia Diaz-Gimeno, Phillip R. Bennett, David A. MacIntyre, Gustavo Stolovitzky, Susan V. Lynch, Jake Albrecht, Nardhy Gomez-Lopez, Roberto Romero, David K. Stevenson, Nima Aghaeepour, Adi L. Tarca, James C. Costello, Marina Sirota Cell Reports Medicine, 2024
METROFOOD-IT: A data platform proposal using Agrifood Smart Data Model Pierpaolo Di Bitonto, Lorenzo De Trizio, Michele Magarelli, Domenico Diacono, Pierfrancesco Novielli, Donato Romano, Claudia Zoani, Roberto Bellotti, Sabina Tangaro 2024 IEEE International Workshop on Metrology for Industry 4 0 and Iot Metroind4 0 and Iot 2024 Proceedings, 2024
Innovative Virtual Reality Based Training in the Agri-Food Sector: Insights from METROFOOD-IT Pierpaolo Di Bitonto, Lorenzo De Trizio, Michele Magarelli, Donato Romano, Pierfrancesco Novielli, Rameez Ahsen, Cesare Manetti, Claudia Zoani, Giovanni Sanesi, Maria De Angelis, Roberto Bellotti, Sabina Tangaro 2024 7th IEEE International Humanitarian Technologies Conference Ihtc 2024, 2024
From data to nutrition: the impact of computing infrastructure and artificial intelligence Pierpaolo Di Bitonto, Michele Magarelli, Pierfrancesco Novielli, Donato Romano, Domenico Diacono, Lorenzo de Trizio, Angelo Mariano, Claudia Zoani, Riccardo Ferrero, Alessandra Manzin, Maria De Angelis, Roberto Bellotti, Sabina Tangaro Exploration of Foods and Foodomics, 2024
A Dementia mortality rates dataset in Italy (2012–2019) Alessandro Fania, Alfonso Monaco, Nicola Amoroso, Loredana Bellantuono, Roberto Cazzolla Gatti, Najada Firza, Antonio Lacalamita, Ester Pantaleo, Sabina Tangaro, Alena Velichevskaya, Roberto Bellotti Scientific Data, 2023
An eXplainable Artificial Intelligence analysis of Raman spectra for thyroid cancer diagnosis Loredana Bellantuono, Raffaele Tommasi, Ester Pantaleo, Martina Verri, Nicola Amoroso, Pierfilippo Crucitti, Michael Di Gioacchino, Filippo Longo, Alfonso Monaco, Anda Mihaela Naciu, Andrea Palermo, Chiara Taffon, Sabina Tangaro, Anna Crescenzi, Armida Sodo, Roberto Bellotti Scientific Reports, 2023
The verbalization of numbers: An explainable framework for tourism online reviews Francesco De Nicolò, Loredana Bellantuono, Dario Borzì, Matteo Bregonzio, Roberto Cilli, Leone De Marco, Angela Lombardi, Ester Pantaleo, Luca Petruzzellis, Ariona Shashaj, Sabina Tangaro, Alfonso Monaco, Nicola Amoroso, Roberto Bellotti International Journal of Engineering Business Management, 2023
Machine learning approaches in microbiome research: challenges and best practices Georgios Papoutsoglou, Sonia Tarazona, Marta B. Lopes, Thomas Klammsteiner, Eliana Ibrahimi, Julia Eckenberger, Pierfrancesco Novielli, Alberto Tonda, Andrea Simeon, Rajesh Shigdel, Stéphane Béreux, Giacomo Vitali, Sabina Tangaro, Leo Lahti, Andriy Temko, Marcus J. Claesson, Magali Berland Frontiers in Microbiology, 2023
Best Practices in Knowledge Transfer: Insights from Top Universities Annamaria Demarinis Loiotile, Francesco De Nicolò, Adriana Agrimi, Loredana Bellantuono, Marianna La Rocca, Alfonso Monaco, Ester Pantaleo, Sabina Tangaro, Nicola Amoroso, Roberto Bellotti Sustainability Switzerland, 2022
PSInSAR Monitoring of Coastal Cliffs at Torre a Mare, Apulia, Italy Nicola Amoroso, Roberto Cilli, Daniela Iasillo, Vincenzo Massimi, Alfonso Monaco, Davide Oscar Nitti, Raffaele Nutricato, Sabina Tangaro, Alberto Refice, Antonio Zilli, Roberto Bellotti 2022 IEEE Mediterranean and Middle East Geoscience and Remote Sensing Symposium M2garss 2022 Proceedings, 2022
A Clinical Decision Support System for Predicting Invasive Breast Cancer Recurrence: Preliminary Results Raffaella Massafra, Agnese Latorre, Annarita Fanizzi, Roberto Bellotti, Vittorio Didonna, Francesco Giotta, Daniele La Forgia, Annalisa Nardone, Maria Pastena, Cosmo Maurizio Ressa, Lucia Rinaldi, Anna Orsola Maria Russo, Pasquale Tamborra, Sabina Tangaro, Alfredo Zito, Vito Lorusso Frontiers in Oncology, 2021
Artificial intelligence applications in medical imaging: A review of the medical physics research in Italy Michele Avanzo, Massimiliano Porzio, Leda Lorenzon, Lisa Milan, Roberto Sghedoni, Giorgio Russo, Raffaella Massafra, Annarita Fanizzi, Andrea Barucci, Veronica Ardu, Marco Branchini, Marco Giannelli, Elena Gallio, Savino Cilla, Sabina Tangaro, Angela Lombardi, Giovanni Pirrone, Elena De Martin, Alessia Giuliano, Gina Belmonte, Serenella Russo, Osvaldo Rampado, Giovanni Mettivier Physica Medica, 2021
A primer on machine learning techniques for genomic applications Alfonso Monaco, Ester Pantaleo, Nicola Amoroso, Antonio Lacalamita, Claudio Lo Giudice, Adriano Fonzino, Bruno Fosso, Ernesto Picardi, Sabina Tangaro, Graziano Pesole, Roberto Bellotti Computational and Structural Biotechnology Journal, 2021
Assessment of network module identification across complex diseases The DREAM Module Identification Challenge Consortium, Sarvenaz Choobdar, Mehmet E. Ahsen, Jake Crawford, Mattia Tomasoni, Tao Fang, David Lamparter, Junyuan Lin, Benjamin Hescott, Xiaozhe Hu, Johnathan Mercer, Ted Natoli, Rajiv Narayan, Aravind Subramanian, Jitao D. Zhang, Gustavo Stolovitzky, Zoltán Kutalik, Kasper Lage, Donna K. Slonim, Julio Saez-Rodriguez, Lenore J. Cowen, Sven Bergmann, Daniel Marbach Nature Methods, 2019
Role of the contrast-enhanced spectral mammography for the diagnosis of breast metastases from extramammary neoplasms Journal of B U on, 2019
Deep learning and multiplex networks for accurate modeling of brain age Nicola Amoroso, Marianna La Rocca, Loredana Bellantuono, Domenico Diacono, Annarita Fanizzi, Eufemia Lella, Angela Lombardi, Tommaso Maggipinto, Alfonso Monaco, Sabina Tangaro, Roberto Bellotti Frontiers in Aging Neuroscience, 2019
A combined approach of multiscale texture analysis and interest point/corner detectors for microcalcifications diagnosis Liliana Losurdo, Annarita Fanizzi, Teresa M. A. Basile, Roberto Bellotti, Ubaldo Bottigli, Rosalba Dentamaro, Vittorio Didonna, Alfonso Fausto, Raffaella Massafra, Alfonso Monaco, Marco Moschetta, Ondina Popescu, Pasquale Tamborra, Sabina Tangaro, Daniele La Forgia Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2018
A Gradient-Based Approach for Breast DCE-MRI Analysis L. Losurdo, T. M. A. Basile, A. Fanizzi, R. Bellotti, U. Bottigli, R. Carbonara, R. Dentamaro, D. Diacono, V. Didonna, A. Lombardi, F. Giotta, C. Guaragnella, A. Mangia, R. Massafra, P. Tamborra, S. Tangaro, D. La Forgia Biomed Research International, 2018
A multi-layer MRI description of Parkinson's diseas Nicola Amoroso, Marianna La Rocca, Roberto Bellotti, Sabina Tangaro, Eufemia Lella Proceedings of SPIE the International Society for Optical Engineering, 2017
Salient networks: A novel application to study brain connectivity Nicola Amoroso, Roberto Bellotti, Domenico Diacono, Marianna La Rocca, Sabina Tangaro Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2017
Machine learning for the assessment of Alzheimer's disease through DTI Nicola Amoroso, Sabina Tangaro, Eufemia Lella, Roberto Bellotti, Domenico Diacono, Tommaso Maggipinto, Alfonso Monaco, Marianna La Rocca Proceedings of SPIE the International Society for Optical Engineering, 2017
Hough Transform for Clustered Microcalcifications Detection in Full-Field Digital Mammograms Teresa M. A. Basile, Annarita Fanizzi, Liliana Losurdo, Roberto Bellotti, Sonia Tangaro, Daniele La Forgia, Vittorio Didonna, Raffaella Massafra, Pasquale Tamborra, Marco Moschetta, Ubaldo Bottigli, Rosalba Dentamaro, Alfonso Fausto, N. Amoroso Proceedings of SPIE the International Society for Optical Engineering, 2017
Topological complex networks properties for gene community detection strategy: DRD2 case study Anna Monda, Nicola Amoroso, Teresa Maria Altomare Basile, Roberto Bellotti, Alessandro Bertolino, Giuseppe Blasi, Pasquale Di Carlo, Annarita Fanizzi, Marianna La Rocca, Tommaso Maggipinto, Alfonso Monaco, Marco Papalino, Giulio Pergola, Sabina Tangaro Springer Proceedings in Physics, 2017
MRI analysis for hippocampus segmentation on a distributed infrastructure S. Tangaro, N. Amoroso, M. Antonacci, M. Boccardi, M. Bocchetta, A. Chincarini, D. Diacono, G. Donvito, R. Errico, G. B. Frisoni, T. Maggipinto, A. Monaco, F. Sensi, A. Tateo, R. Bellotti 2016 IEEE International Symposium on Medical Measurements and Applications Memea 2016 Proceedings, 2016
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease Genevera I. Allen, Nicola Amoroso, Catalina Anghel, Venkat Balagurusamy, Christopher J. Bare, Derek Beaton, Roberto Bellotti, David A. Bennett, Kevin L. Boehme, Paul C. Boutros, Laura Caberlotto, Cristian Caloian, Frederick Campbell, Elias Chaibub Neto, Yu‐Chuan Chang, Beibei Chen, Chien‐Yu Chen, Ting‐Ying Chien, Tim Clark, Sudeshna Das, Christos Davatzikos, Jieyao Deng, Donna Dillenberger, Richard J.B. Dobson, Qilin Dong, Jimit Doshi, Denise Duma, Rosangela Errico, Guray Erus, Evan Everett, David W. Fardo, Stephen H. Friend, Holger Fröhlich, Jessica Gan, Peter St George‐Hyslop, Satrajit S. Ghosh, Enrico Glaab, Robert C. Green, Yuanfang Guan, Ming‐Yi Hong, Chao Huang, Jinseub Hwang, Joseph Ibrahim, Paolo Inglese, Anandhi Iyappan, Qijia Jiang, Yuriko Katsumata, John S.K. Kauwe, Arno Klein, Dehan Kong, Roland Krause, Emilie Lalonde, Mario Lauria, Eunjee Lee, Xihui Lin, Zhandong Liu, Julie Livingstone, Benjamin A. Logsdon, Simon Lovestone, Tsung‐wei Ma, Ashutosh Malhotra, Lara M. Mangravite, Taylor J. Maxwell, Emily Merrill, John Nagorski, Aishwarya Namasivayam, Manjari Narayan, Mufassra Naz, Stephen J. Newhouse, Thea C. Norman, Ramil N. Nurtdinov, Yen‐Jen Oyang, Yudi Pawitan, Shengwen Peng, Mette A. Peters, Stephen R. Piccolo, Paurush Praveen, Corrado Priami, Veronica Y. Sabelnykova, Philipp Senger, Xia Shen, Andrew Simmons, Aristeidis Sotiras, Gustavo Stolovitzky, Sabina Tangaro, Andrea Tateo, Yi‐An Tung, Nicholas J. Tustison, Erdem Varol, George Vradenburg, Michael W. Weiner, Guanghua Xiao, Lei Xie, Yang Xie, Jia Xu, Hojin Yang, Xiaowei Zhan, Yunyun Zhou, Fan Zhu, Hongtu Zhu, Shanfeng Zhu, Alzheimer's Disease Neuroimaging Initiative Alzheimer S and Dementia, 2016
Medical Physics Applications in Bari ReCaS Farm N. Amoroso, M. Antonacci, R. Bellotti, G. Donvito, R. Errico, G. Maggi, A. Monaco, P. Notarangelo, S. Tangaro, A. Tateo High Performance Scientific Computing Using Distributed Infrastructures Results and Scientific Applications Derived from the Italian Pon Recas Project, 2016
The ReCaS Project: The Bari Infrastructure M. Antonacci, R. Bellotti, F. Cafagna, M. de Palma, D. Diacono, G. Donvito, A. Italiano, R. Gervasoni, G. Maggi, G. Miniello, A. Monaco, S. Nicotri, S. Nuzzo, P. Notarangelo, B. Santeramo, G. Selvaggi, L. Silvestris, V. Spinoso, S. Tangaro, E. Tinelli, R. Valentini High Performance Scientific Computing Using Distributed Infrastructures Results and Scientific Applications Derived from the Italian Pon Recas Project, 2016
Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: The CADDementia challenge Esther E. Bron, Marion Smits, Wiesje M. van der Flier, Hugo Vrenken, Frederik Barkhof, Philip Scheltens, Janne M. Papma, Rebecca M.E. Steketee, Carolina Méndez Orellana, Rozanna Meijboom, Madalena Pinto, Joana R. Meireles, Carolina Garrett, António J. Bastos-Leite, Ahmed Abdulkadir, Olaf Ronneberger, Nicola Amoroso, Roberto Bellotti, David Cárdenas-Peña, Andrés M. Álvarez-Meza, Chester V. Dolph, Khan M. Iftekharuddin, Simon F. Eskildsen, Pierrick Coupé, Vladimir S. Fonov, Katja Franke, Christian Gaser, Christian Ledig, Ricardo Guerrero, Tong Tong, Katherine R. Gray, Elaheh Moradi, Jussi Tohka, Alexandre Routier, Stanley Durrleman, Alessia Sarica, Giuseppe Di Fatta, Francesco Sensi, Andrea Chincarini, Garry M. Smith, Zhivko V. Stoyanov, Lauge Sørensen, Mads Nielsen, Sabina Tangaro, Paolo Inglese, Christian Wachinger, Martin Reuter, John C. van Swieten, Wiro J. Niessen, Stefan Klein Neuroimage, 2015
An hippocampal segmentation tool within an open cloud infrastructure Nicola Amoroso, Sabina Tangaro, Rosangela Errico, Elena Garuccio, Anna Monda, Francesco Sensi, Andrea Tateo, Roberto Bellotti, [Authorinst]for the Alzheimer’s Dis Initiative Lecture Notes in Computer Science, 2015
Feature selection based on machine learning in MRIs for hippocampal segmentation Sabina Tangaro, Nicola Amoroso, Massimo Brescia, Stefano Cavuoti, Andrea Chincarini, Rosangela Errico, Paolo Inglese, Giuseppe Longo, Rosalia Maglietta, Andrea Tateo, Giuseppe Riccio, Roberto Bellotti Computational and Mathematical Methods in Medicine, 2015
Random forest classification for hippocampal segmentation in 3D MR images Rosalia Maglietta, Nicola Amoroso, Stefania Bruno, Andrea Chincarini, Giovanni Frisoni, Paolo Inglese, Sabina Tangaro, Andrea Tateo, Roberto Bellotti Proceedings 2013 12th International Conference on Machine Learning and Applications Icmla 2013, 2013
Alzheimer’s disease markers from structural MRI and FDG-PET brain images Andrea Chincarini, Paolo Bosco, Gianluca Gemme, Silvia Morbelli, Dario Arnaldi, Francesco Sensi, Ilaria Solano, Nicola Amoroso, Sabina Tangaro, Renata Longo, Sandro Squarcia, Flavio Nobili European Physical Journal Plus, 2012
Automated Shape Analysis landmarks detection for medical image processing Computational Modelling of Objects Represented in Images Fundamentals Methods and Applications III Proceedings of the International Symposium Compimage 2012, 2012
Automatic lung segmentation in CT images with accurate handling of the hilar region Giorgio De Nunzio, Eleonora Tommasi, Antonella Agrusti, Rosella Cataldo, Ivan De Mitri, Marco Favetta, Silvio Maglio, Andrea Massafra, Maurizio Quarta, Massimo Torsello, Ilaria Zecca, Roberto Bellotti, Sabina Tangaro, Piero Calvini, Niccolò Camarlinghi, Fabio Falaschi, Piergiorgio Cerello, Piernicola Oliva Journal of Digital Imaging, 2011
Comparing and combining algorithms for computer-aided detection of pulmonary nodules in computed tomography scans: The ANODE09 study Bram van Ginneken, Samuel G. Armato, Bartjan de Hoop, Saskia van Amelsvoort-van de Vorst, Thomas Duindam, Meindert Niemeijer, Keelin Murphy, Arnold Schilham, Alessandra Retico, Maria Evelina Fantacci, Niccolò Camarlinghi, Francesco Bagagli, Ilaria Gori, Takeshi Hara, Hiroshi Fujita, Gianfranco Gargano, Roberto Bellotti, Sabina Tangaro, Lourdes Bolaños, Francesco De Carlo, Piergiorgio Cerello, Sorin Cristian Cheran, Ernesto Lopez Torres, Mathias Prokop Medical Image Analysis, 2010
MAGIC-5: An Italian mammographic database of digitised images for research S. Tangaro, R. Bellotti, F. De Carlo, G. Gargano, E. Lattanzio, P. Monno, R. Massafra, P. Delogu, M. E. Fantacci, A. Retico, M. Bazzocchi, S. Bagnasco, P. Cerello, S. C. Cheran, E. Lopez Torres, E. Zanon, A. Lauria, A. Sodano, D. Cascio, F. Fauci, R. Magro, G. Raso, R. Ienzi, U. Bottigli, G. L. Masala, P. Oliva, G. Meloni, A. P. Caricato, R. Cataldo Radiologia Medica, 2008
A novel Active Contour Model algorithm for contour detection in complex objects G. Gargano, R. Bellotti, F. de Carlo, S. Tangaro, E. Tommasi, M. Castellano, P. Cerello, S.C. Cheran, C. Fulcheri Proceedings of the 2007 IEEE International Conference on Computational Intelligence for Measurement Systems and Applications Cimsa, 2007
Ant Colonies for the reconstruction of artificial 3D Objects P. Cerello, S.C. Cheran, G. Gargano, R. Bellotti, F. de Carlo, S. Tangaro, C. Fulcheri, Torres E. Lopez, E. Tommasi Proceedings of the 2007 IEEE International Conference on Computational Intelligence for Measurement Systems and Applications Cimsa, 2007
Distributed medical images analysis on a Grid infrastructure R. Bellotti, P. Cerello, S. Tangaro, V. Bevilacqua, M. Castellano, G. Mastronardi, F. De Carlo, S. Bagnasco, U. Bottigli, R. Cataldo, E. Catanzariti, S.C. Cheran, P. Delogu, I. De Mitri, G. De Nunzio, M.E. Fantacci, F. Fauci, G. Gargano, B. Golosio, P.L. Indovina, A. Lauria, E. Lopez Torres, R. Magro, G.L. Masala, R. Massafra, P. Oliva, A. Preite Martinez, M. Quarta, G. Raso, A. Retico, M. Sitta, S. Stumbo, A. Tata, S. Squarcia, A. Schenone, E. Molinari, B. Canesi Future Generation Computer Systems, 2007
Mass lesion detection in mammographic images using Haralik textural features Proceedings of the International Symposium Compimage 2006 Computational Modelling of Objects Represented in Images Fundamentals Methods and Applications, 2007
GPCALMA: An Italian mammographic database of digitized images for research Adele Lauria, Raffaella Massafra, Sabina Sonia Tangaro, Roberto Bellotti, MariaEvelina Fantacci, Pasquale Delogu, Ernesto Lopez Torres, Piergiorgio Cerello, Francesco Fauci, Rosario Magro, Ubaldo Bottigli Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2006
A completely automated CAD system for mass detection in a large mammographic database R. Bellotti, F. De Carlo, S. Tangaro, G. Gargano, G. Maggipinto, M. Castellano, R. Massafra, D. Cascio, F. Fauci, R. Magro, G. Raso, A. Lauria, G. Forni, S. Bagnasco, P. Cerello, E. Zanon, S. C. Cheran, E. Lopez Torres, U. Bottigli, G. L. Masala, P. Oliva, A. Retico, M. E. Fantacci, R. Cataldo, I. De Mitri, G. De Nunzio Medical Physics, 2006
Dissimilarity application for medical imaging classification Wmsci 2005 the 9th World Multi Conference on Systemics Cybernetics and Informatics Proceedings, 2005
Classifiers trained on dissimilarity representation of medical pattern: A comparative study Nuovo Cimento Della Societa Italiana Di Fisica C, 2005
A massive lesion detection algorithm in mammography Francesco Fauci, Giuseppe Raso, Rosario Magro, Giustina Forni, Adele Lauria, Stefano Bagnasco, Piergiorgio Cerello, Sorin C. Cheran, Ernesto Lopez Torres, Robero Bellotti, Francesco De carlo, Gianfranco Gargano, Sonia Tangaro, Ivan De Mitri, Giorgio De Nunzio, Rossella Cataldo Physica Medica, 2005
GPCALMA: A Grid-based tool for mammographic screening S. Bagnasco, U. Bottigli, S. C. Cheran, P. Delogu, M. E. Fantacci, F. Fauci, G. Forni, A. Lauria, E. Lopez Torres, R. Magro, G. L. Masala, P. Oliva, R. Palmiero, L. Ramello, G. Raso, A. Retico, M. Sitta, S. Stumbo, S. Tangaro, E. Zanon, P. Cerello Methods of Information in Medicine, 2005
Mammogram segmentation by contour searching and massive lesion classification with neural network IEEE Nuclear Science Symposium Conference Record, 2004
The MAGIC-5 project: Medical applications on a grid infrastructure connection IEEE Nuclear Science Symposium Conference Record, 2004
Measurements of spectral and position resolution on a 16×16 pixel CZT imaging hard X-ray detector Stefano Del Sordo, Gaetano Agnetta, B. Biondo, Ezio Caroli, Filippo Celi, Ariano Donati, Salvatore Giarrusso, A. Mangano, R. Montanti, Francesco Russo, Filomena Schiavone, John B. Stephen, M. Strazzeri, Giulio Ventura, Giovanni Pareschi, L. Abbene, Francesco Fauci, Giuseppe Raso, V. Radicci, S. Tangaro, Piernicola Oliva, Simone Stumbo Proceedings of SPIE the International Society for Optical Engineering, 2004
FLUXEN portable equipment for direct X-ray spectra measurements S. Aiello, U. Bottigli, F. Fauci, B. Golosio, D. Lo Presti, G.L. Masala, P. Oliva, G. Raso, S. Stumbo, S. Tangaro Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment, 2004
Diagnostic performance of radiologists with and without different CAD systems for mammography Adele Lauria, Maria E. Fantacci, Ubaldo Bottigli, Pasquale Delogu, Francesco Fauci, Bruno Golosio, Pietro L. Indovina, Giovanni L. Masala, Piernicola Oliva, Rosa Palmiero, Giuseppe Raso, Simone Stumbo, Sabina Tangaro Proceedings of SPIE the International Society for Optical Engineering, 2003
GPCALMA, a mammographic CAD in a GRID connection U Bottigli, P Cerello, P Delogu, M.E Fantacci, F Fauci, B Golosio, A Lauria, E Lopez Torres, R Magro, G.L Masala, P Oliva, R Palmiero, G Raso, A Retico, S Stumbo, S Tangaro International Congress Series, 2003
Search of microcalcification clusters with the CALMA CAD station Maria E. Fantacci, Ubaldo Bottigli, Pasquale Delogu, Francesco Fauci, Bruno Golosio, Adele Lauria, Rosa Palmiero, Giuseppe Raso, Simone Stumbo, Sabina Tangaro Proceedings of SPIE the International Society for Optical Engineering, 2002
The CALMA project S.R. Amendolia, M.G. Bisogni, U. Bottigli, A. Ceccopieri, P. Delogu, G. Dipasquale, M.E. Fantacci, E. Lorenzini, A. Marchi, V.M. Marzulli, P. Oliva, R. Palmiero, M. Reggiani, V. Rosso, A. Stefanini, S. Stumbo, S. Tangaro, O. Venier Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment, 2001
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