Stem cell, Stress Physiology, Lactation Physiology, Regenerative medicine
31
Scopus Publications
724
Scholar Citations
14
Scholar h-index
17
Scholar i10-index
Scopus Publications
Digestion in Non-Ruminant Animals Fundamentals of Livestock and Poultry Management, 2026
Digestion and Reproduction in Poultry Fundamentals of Livestock and Poultry Management, 2026
Experimental Physiology Physiopathology of Clinical Disorders, 2026
Physiology of Membranes Physiopathology of Clinical Disorders, 2026
Physiology of the Digestive System of Ruminants Vipin Maurya, Mukesh Kumar Bharti Principles of Veterinary Animal Physiology, 2025 This chapter discusses the physiology of digestion in ruminant animals like cows, sheep, and goats. Ruminant animals possess a specialized digestive system tailored to efficiently utilize diets high in plant fibers through microbial fermentation. Unlike monogastric animals, ruminants have a complex four-chambered stomach: the rumen, reticulum, omasum, and abomasum. This adaptation enables them to extract essential nutrients from fibrous plant materials that are otherwise indigestible by many other animals. The rumen, the largest compartment, acts as a fermentation vat where a diverse microbiome comprising bacteria, protozoa, and fungi breaks down plant fibers into volatile fatty acids (VFAs), gases, and microbial protein. VFAs, primarily acetic, propionic, and butyric acids, are absorbed directly through the rumen wall and serve as the principal energy source for the host animal. The reticulum, adjacent to the rumen, plays a crucial role in forming cud and regurgitating partially digested feed. The omasum, characterized by its multiple folds, is responsible for the absorption of water and nutrients and the reduction of particle size before feed proceeds to the abomasum. The abomasum, often referred to as the “true stomach,” functions similarly to a monogastric stomach by secreting hydrochloric acid and digestive enzymes, which break down the remaining feed particles and microbial proteins for absorption in the small intestine. This sophisticated digestive system allows ruminants to convert low-quality forages into high-quality protein and energy, making them efficient producers of meat, milk, and fiber. Understanding the intricacies of ruminant digestion is essential for optimizing animal nutrition, enhancing feed efficiency, and improving overall production performance. Advancements in ruminant digestive research have profound implications for sustainable livestock management. By gaining deeper insights into this system, it is possible to develop feeding strategies that maximize the nutritional potential of ruminants while reducing their environmental footprint.
Physiology of the Excretory System Mukesh Kumar Bharti, P. Thulasiraman, Manish Kumar Principles of Veterinary Animal Physiology, 2025 This chapter discusses the importance of the kidney in the maintenance of the body's internal environment and fluid balance. As far as the renal system is concerned, it consists of a pair of kidneys which produces urine, a ureter that transports urine to urinary bladder, a urinary bladder that stores the urine, and a urethra through which urine voided out. In mammals, the final kidney is the metanephric in origin. The kidneys are described as being retroperitoneal in location, reflecting their position outside the peritoneal cavity. The kidneys of most animals are roughly bean-shaped, with some exceptions in other animals. The nephron is the structural and functional unit of kidney. Blood and nerve supply to the kidney is very extensive, with about one fourth of cardiac output supplied to the kidney for filtration. The tubular part of the nephron is mainly used for concentrating urine, while renal corpuscles are used for filtration of blood. Urine formation, an important function of the kidney, consists of three steps as glomerular filtration, tubular reabsorption, and tubular secretion. Acid-base regulation is one of the basic functions of the kidney through which it maintains the body's balance of acid and base. The kidneys play a very essential role in osmoregulation by controlling the quantity of fluid reabsorbed from the glomerular filtrate.
Clinical Physiology of Lymphatic Disorders Manju G. Preedaa, Thulasiraman Parkunan, Mukesh Kumar Bharti, Archana Mahapatra, Manish Kumar Fundamentals of Veterinary Pathophysiology, 2025 Lymphatic disorders encompass a range of conditions affecting the lymphatic system, which plays a crucial role in maintaining fluid balance, immune function, and fat absorption. Pathophysiologically, these disorders often involve either obstruction or dysfunction of lymphatic vessels, leading to lymphedema, characterized by the accumulation of lymphatic fluid in tissues. Primary lymphedema arises from congenital malformations of the lymphatic system, while secondary lymphedema results from damage or obstruction caused by infection, surgery, radiation, or malignancy. Chronic inflammation and fibrosis are common sequelae, exacerbating fluid accumulation and tissue swelling. The impaired lymphatic drainage in these disorders disrupts immune cell trafficking and can result in recurrent infections and delayed wound healing. Additionally, lymphatic dysfunction may contribute to the development of lymphangiectasia and chylous effusions, in which lymph leaks into body cavities. Molecular studies have highlighted the roles of various genetic mutations and signaling pathways, such as vascular endothelial growth factor-C (VEGF-C)/vascular endothelial growth factor receptor 3 (VEGFR-3), in the development and progression of lymphatic disorders. Therapeutically, management focuses on symptomatic relief through physical therapies, compression garments, and, in severe cases, surgical interventions. This chapter compiles information to elucidate the complex pathophysiology of lymphatic disorders, which is crucial for developing targeted treatments and enhancing patient outcomes.
Physiology of the Lactation System G. Mohamed Hasif, Manju G Preedaa, Nikhil Kumar Tej, Manish Kumar, Mukesh Kumar Bharti, Harivarman Segar, Thulasiraman Parkunan Principles of Veterinary Animal Physiology, 2025 The mammary gland, an intricate organ essential for the nourishment of mammalian offspring, is a marvel of biological engineering. Its complex structure, consisting of a tubulo-alveolar ductal system, is meticulously designed for the production and transportation of milk, culminating in teats and areolas that facilitate the vital process of milk ejection. The gland's integrity is maintained by suspensory ligaments, while its function is supported by a dedicated blood supply, primarily through the mammary arteries, which are crucial for delivering nutrients and expelling waste. The lymphatic network plays a pivotal role in immune defense and maintaining fluid equilibrium. The process of mammogenesis, governed by a symphony of hormonal signals and growth factors, directs the development and differentiation of the mammary gland. This process is further supported by the physiology of the surrounding fat pad, which contributes to the gland's growth and functionality. Lactogenesis and galactopoiesis are the processes that initiate and sustain milk production, respectively, and are regulated by a complex hormonal interplay. Following the cessation of lactation, the mammary gland undergoes involution, a phase characterized by tissue remodeling and programmed cell death. Challenges such as mastitis and agalactia, prevalent in dairy cows, underscore the importance of understanding mammary gland biology to enhance lactation efficiency, promote animal welfare, and by extension, benefit human health. This comprehensive understanding is not only fundamental to animal production but also has implications for human medicine, particularly in the context of dairying and related health issues.
Pathogenicity of Beauveria bassiana to Life Stages of Lepidopteran Pests A Tiwari, R Singh, G Singh, DV Singh, G Singh, M Bharti Indian Journal of Entomology, 899-901 , 2026 2026
Physiology of the Digestive System of Ruminants V Maurya, MK Bharti Principles of Veterinary Animal Physiology, 147-153 , 2025 2025 Citations: 2
Physiology of the Excretory System MK Bharti, P Thulasiraman, M Kumar Principles of Veterinary Animal Physiology, 168-178 , 2025 2025
Physiology of the Lactation System GM Hasif, MG Preedaa, NK Tej, M Kumar, MK Bharti, H Segar, ... Principles of Veterinary Animal Physiology, 207-223 , 2025 2025
16 PhysiologySystemof of the Digestive V Maurya, MK Bharti Principles of Veterinary Animal Physiology, 147 , 2025 2025
Clinical 18 Lymphatic Physiology Disorders of MG Preedaa, T Parkunan, MK Bharti, A Mahapatra, M Kumar Fundamentals of Veterinary Pathophysiology, 187 , 2025 2025 Citations: 1
Impact of egg storage temperature and stage of laying on hatchability, fertility and chick quality in Kadaknath chickens A KUMARI, UK TRIPATHI, M KUMAR, A KUMAR, MK BHARTI, KK SARAF Indian Journal of Poultry Science 60 (2), 2 , 2025 2025
Assessment of Biofilm Formation and Shiga-like Toxin Genes in ESBL-producing E. coli Isolates Recovered from Retail Salad Vegetables in Mirzapur District, Uttar Pradesh, India AP Achyutrao, S Yadav, S Kaushik, R Kumar, M Kumar, T Parkunan, ... Indian Journal of Agricultural Research 59 (11), 1683-1690 , 2025 2025 Citations: 1
Exploration of immunomodulatory mechanism of caprine Wharton’s jelly derived mesenchymal stem cells I Baiju, MK Bharti, A Somal, S Pandey, IA Bhat, A Joseph, V Chandra, ... Cellular Immunology 405, 104879 , 2024 2024 Citations: 3
Herbal feed additives and supplements for a sustainable ruminant production T Parkunan, MK Bharti, T Govindasamy, M Kumar, DK Ramasamy, ... Feed Additives and Supplements for Ruminants, 197-234 , 2024 2024 Citations: 8
Progesterone supplemented uterine epithelial cell co-culture improves in vitro quality embryo production in buffalo S Pandey, MK Bharti, IA Bhat, V Chandra, SG TARU JOURNAL OF REPRODUCTIVE HEALTHCARE AND MEDICINE Учредители: Scientific … , 2024 2024 Citations: 1
Isolation and propagation of classical swine fever virus in porcine Wharton’s Jelly mesenchymal stem cells NR Tomar, IA Bhat, MK Bharti, JK John, V Sharma, V Chandra, ... Animal Biotechnology 33 (4), 629-637 , 2022 2022 Citations: 6
Smad4 and γ-secretase knock-down effect on osteogenic differentiation mediated via Runx2 in canine mesenchymal stem cells U Shabir, IA Bhat, BA Pir, MK Bharti, S Pandey, SK Gutulla, M Sarkar, ... Research in veterinary science 145, 116-124 , 2022 2022 Citations: 5
Comparative evaluation of fracture healing potential of differentiated and undifferentiated guinea pig and canine bone marrow-derived mesenchymal stem cells in a guinea pig model BA Peer, AR Bhat, U Shabir, MK Bharti, IA Bhat, S Pandey, K Sharun, ... Tissue and Cell 76, 101768 , 2022 2022 Citations: 12
Biomaterials and Scaffolds in Stem Cell Therapy MK Bharti, V Chandra, GT Sharma Stem Cells in Veterinary Science, 255-269 , 2022 2022 Citations: 1
International Journal of Current Microbiology and Applied Sciences SS Mohapatra, J Mukherjee, MK Bharti, M Kumar, T Parkunan Int. J. Curr. Microbiol. App. Sci 11 (01), 34-45 , 2022 2022
Expression profile of adhesion molecules in blastocyst vis-a-vis uterine epithelial cells S Pandey, HL Devi, IA Bhat, B Indu, MK Bharti, U Shabir, BA Peer, ... Theriogenology 170, 36-45 , 2021 2021 Citations: 6
Comparative analysis of the immunomodulatory potential of caprine fetal adnexa derived mesenchymal stem cells A Somal, IA Bhat, S Pandey, MM Ansari, B Indu, BSK Panda, MK Bharti, ... Molecular biology reports 48 (5), 3913-3923 , 2021 2021 Citations: 6
Progesterone modulates adhesion molecules in uterine epithelial cells and in vitro embryo production in buffalo S Pandey, I Ahmad Bhat, M Kumar Bharti, U Shabir, B Ahmad Peer, ... Reproduction in Domestic Animals 55 (7), 833-843 , 2020 2020 Citations: 8
Mesenchymal stem cell‐conditioned media: A novel alternative of stem cell therapy for quality wound healing A Joseph, I Baiju, IA Bhat, S Pandey, M Bharti, M Verma, A Pratap Singh, ... Journal of cellular physiology 235 (7-8), 5555-5569 , 2020 2020 Citations: 118
MOST CITED SCHOLAR PUBLICATIONS
Mesenchymal stem cell‐conditioned media: A novel alternative of stem cell therapy for quality wound healing A Joseph, I Baiju, IA Bhat, S Pandey, M Bharti, M Verma, A Pratap Singh, ... Journal of cellular physiology 235 (7-8), 5555-5569 , 2020 2020 Citations: 118
Expression analysis of Toll like receptors and interleukins in Tharparkar cattle during acclimation to heat stress exposure J Bharati, SS Dangi, SR Mishra, VS Chouhan, V Verma, O Shankar, ... Journal of Thermal Biology 65, 48-56 , 2017 2017 Citations: 88
Expression dynamics of HSP70 during chronic heat stress in Tharparkar cattle J Bharati, SS Dangi, VS Chouhan, SR Mishra, MK Bharti, V Verma, ... International journal of biometeorology 61 (6), 1017-1027 , 2017 2017 Citations: 86
An allogenic therapeutic strategy for canine spinal cord injury using mesenchymal stem cells IA Bhat, S TB, A Somal, S Pandey, MK Bharti, BSK Panda, I B, M Verma, ... Journal of cellular physiology 234 (3), 2705-2718 , 2019 2019 Citations: 61
Expression and localization of fibroblast growth factor (FGF) family in buffalo ovarian follicle during different stages of development and modulatory role of FGF2 on … SR Mishra, N Thakur, A Somal, MS Parmar, R Reshma, G Rajesh, ... Research in Veterinary Science 108, 98-111 , 2016 2016 Citations: 50
Impact of cryopreservation on caprine fetal adnexa derived stem cells and its evaluation for growth kinetics, phenotypic characterization, and wound healing potential in … A Somal, IA Bhat, I B, AP Singh, BSK Panda, PA Desingu, S Pandey, ... Journal of cellular physiology 232 (8), 2186-2200 , 2017 2017 Citations: 30
Germ cell mutagenicity of phthalic acid in mice AM Jha, AC Singh, M Bharti Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 422 (2 … , 1998 1998 Citations: 30
Leptin supplementation in vitro improved developmental competence of buffalo oocytes and embryos BSK Panda, S Pandey, A Somal, MS Parmar, IA Bhat, I Baiju, MK Bharti, ... Theriogenology 98, 116-122 , 2017 2017 Citations: 25
Impact of oocyte-secreted factors on its developmental competence in buffalo S Gupta, S Pandey, MS Parmar, A Somal, A Paul, BSK Panda, IA Bhat, ... Zygote 25 (3), 313-320 , 2017 2017 Citations: 25
Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis … SR Mishra, MS Parmar, VP Yadav, R Reshma, J Bharati, MK Bharti, ... Reproduction in Domestic Animals 51 (6), 855-869 , 2016 2016 Citations: 24
Effect of cryopreservation on therapeutic potential of canine bone marrow derived mesenchymal stem cells augmented mesh scaffold for wound healing in guinea pig MK Bharti, IA Bhat, S Pandey, U Shabir, BA Peer, B Indu, AR Bhat, ... Biomedicine & Pharmacotherapy 121, 109573 , 2020 2020 Citations: 19
Modulatory role of leptin on ovarian functions in water buffalo (Bubalus bubalis) R Reshma, SR Mishra, N Thakur, MS Parmar, A Somal, MK Bharti, ... Theriogenology 86 (7), 1720-1739 , 2016 2016 Citations: 18
Clastogenicity of carbazole in mouse bone marrow cells in vivo AM Jha, AC Singh, MK Bharti Mutation Research/Genetic Toxicology and Environmental Mutagenesis 521 (1-2 … , 2002 2002 Citations: 16
Expression and localization of fibroblast growth factor (FGF) family in corpus luteum during different stages of estrous cycle and synergistic role of FGF2 and vascular … SR Mishra, MS Parmar, VS Chouhan, G Rajesh, VP Yadav, MK Bharti, ... Agri Gene 1, 53-68 , 2016 2016 Citations: 14
Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis … SR Mishra, N Thakur, A Somal, MS Parmar, VP Yadav, J Bharati, ... Theriogenology 86 (7), 1818-1833 , 2016 2016 Citations: 13
Comparative evaluation of fracture healing potential of differentiated and undifferentiated guinea pig and canine bone marrow-derived mesenchymal stem cells in a guinea pig model BA Peer, AR Bhat, U Shabir, MK Bharti, IA Bhat, S Pandey, K Sharun, ... Tissue and Cell 76, 101768 , 2022 2022 Citations: 12
Laboratory and imaging techniques for pregnancy diagnosis in animals MK Bharti, N Jacob Journal of Entomology and Zoology Studies 7 (5), 639-647 , 2019 2019 Citations: 10
Expression and localization of fibroblast growth factor 10 (FGF10) in ovarian follicle during different stages development in Buffalo SR Mishra, J Bharati, MK Bharti, G Singh, M Sarkar Asian J Animal and Vet Advan 10, 433-42 , 2015 2015 Citations: 9
Herbal feed additives and supplements for a sustainable ruminant production T Parkunan, MK Bharti, T Govindasamy, M Kumar, DK Ramasamy, ... Feed Additives and Supplements for Ruminants, 197-234 , 2024 2024 Citations: 8
Progesterone modulates adhesion molecules in uterine epithelial cells and in vitro embryo production in buffalo S Pandey, I Ahmad Bhat, M Kumar Bharti, U Shabir, B Ahmad Peer, ... Reproduction in Domestic Animals 55 (7), 833-843 , 2020 2020 Citations: 8