Ana-Iulia Bița

@upb.ro

Department of metallic materials science and physical metallurgy / ​Faculty of Materials Science and Engineering
Politehnica University of Bucharest

Ana-Iulia Bița


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https://researchid.co/anaiulia.bita
Polytechnic University of Bucharest: Bucharest, Romania, RO
2021-03-01 to present | University lecturer Ph.D. Eng. (Faculty of Materials Science and Engineering - Department of Metallic Materials Science and Physical Metallurgy)

S.C. Setro Metal Group S.R.L.: Campulung, Romania, RO
2016-02-18 to 2021-02-28 | Production Engineer (Production)

Polytechnic University of Bucharest: Bucharest, Romania, RO
2014-07-01 to 2015-12-31 | Research Assistant PhD. Eng. (Faculty of Materials Science and Engineering - Department of Metallic Materials Science and Physical Metallurgy)

Polytechnic University of Bucharest: Bucharest, Romania, RO
2010-09-01 to 2011-11-30 | Research Assistant PhD. Eng. (Faculty of Materials Science and Engineering - Department of Metallic Materials Science and Physical Metallurgy)

EDUCATION

Polytechnic University of Bucharest: Bucharest, Romania, RO
2012-10-01 to 2015-12-31 | PhD. Eng. (Faculty of Materials Science and Engineering - Department of Metallic Materials Science and Physical Metallurgy)

Polytechnic University of Bucharest: Bucharest, Romania, RO
2010-10-01 to 2012-07-06 | Master Eng. (Faculty of Materials Science and Engineering - Department of Metallic Materials Science and Physical Metallurgy)

Polytechnic University of Bucharest: Bucharest, Romania, RO
2006-10-01 to 2010-07-06 | Engineer (Faculty of Materials Science and Engineering - Department of Metallic Materials Science and Physical Metallurgy)

"Dimitrie Leonida" Technical College: Bucharest, Romania, RO
2001-09-15 to 2005-06-30 | High School Diploma
23

Scopus Publications

Scopus Publications

  • Mechanical and Computational Fluid Dynamic Models for Magnesium-Based Implants
    Veronica Manescu (Paltanea), Gheorghe Paltanea, Aurora Antoniac, Lucian Gheorghe Gruionu, Alina Robu, et al.
    Materials, 2024
    Today, mechanical properties and fluid flow dynamic analysis are considered to be two of the most important steps in implant design for bone tissue engineering. The mechanical behavior is characterized by Young’s modulus, which must have a value close to that of the human bone, while from the fluid dynamics point of view, the implant permeability and wall shear stress are two parameters directly linked to cell growth, adhesion, and proliferation. In this study, we proposed two simple geometries with a three-dimensional pore network dedicated to a manufacturing route based on a titanium wire waving procedure used as an intermediary step for Mg-based implant fabrication. Implant deformation under different static loads, von Mises stresses, and safety factors were investigated using finite element analysis. The implant permeability was computed based on Darcy’s law following computational fluid dynamic simulations and, based on the pressure drop, was numerically estimated. It was concluded that both models exhibited a permeability close to the human trabecular bone and reduced wall shear stresses within the biological range. As a general finding, the proposed geometries could be useful in orthopedics for bone defect treatment based on numerical analyses because they mimic the trabecular bone properties.
  • PRELIMINARY STUDY OF TiN AND TiCN COATINGS FOR STAINLESS STEEL SURGICAL INSTRUMENTS
    UPB Scientific Bulletin Series B Chemistry and Materials Science, 2024
  • A STUDY OF THE SURFACE FREE ENERGY OF STAINLESS STEEL SURGICAL INSTRUMENTS
    UPB Scientific Bulletin Series B Chemistry and Materials Science, 2024
  • EVALUATION OF SURFACE PROPERTIES FOR DIFFERENT ANODIZED TITANIUM ORTHOPEDIC SCREWS
    UPB Scientific Bulletin Series B Chemistry and Materials Science, 2024
  • Chitosan-Based Biomaterials for Hemostatic Applications: A Review of Recent Advances
    Daniela Gheorghiță, Horațiu Moldovan, Alina Robu, Ana-Iulia Bița, Elena Grosu, et al.
    International Journal of Molecular Sciences, 2023
    Hemorrhage is a detrimental event present in traumatic injury, surgery, and disorders of bleeding that can become life-threatening if not properly managed. Moreover, uncontrolled bleeding can complicate surgical interventions, altering the outcome of surgical procedures. Therefore, to reduce the risk of complications and decrease the risk of morbidity and mortality associated with hemorrhage, it is necessary to use an effective hemostatic agent that ensures the immediate control of bleeding. In recent years, there have been increasingly rapid advances in developing a novel generation of biomaterials with hemostatic properties. Nowadays, a wide array of topical hemostatic agents is available, including chitosan-based biomaterials that have shown outstanding properties such as antibacterial, antifungal, hemostatic, and analgesic activity in addition to their biocompatibility, biodegradability, and wound-healing effects. This review provides an analysis of chitosan-based hemostatic biomaterials and discusses the progress made in their performance, mechanism of action, efficacy, cost, and safety in recent years.
  • INFLUENCE OF HEAT TREATMENT ON MICROSTRUCTURE AND CORROSION BEHAVIOR OF BIODEGRADABLE Mg-Ca ALLOY
    UPB Scientific Bulletin Series B Chemistry and Materials Science, 2023
  • Construction of a magnesium hydroxide/graphene oxide/hydroxyapatite composite coating on Mg–Ca–Zn–Ag alloy to inhibit bacterial infection and promote bone regeneration
    Bo Yuan, Hewei Chen, Rui Zhao, Xuangeng Deng, Guo Chen, et al.
    Bioactive Materials, 2022
  • Essential Oils as Antimicrobial Active Substances in Wound Dressings
    Daniela Gheorghita, Elena Grosu, Alina Robu, Lia Mara Ditu, Iuliana Mihaela Deleanu, et al.
    Materials, 2022
    Wound dressings for skin lesions, such as bedsores or pressure ulcers, are widely used for many patients, both during hospitalization and in subsequent treatment at home. To improve the treatment and shorten the healing time and, therefore, the cost, numerous types of wound dressings have been developed by manufacturers. Considering certain inconveniences related to the intolerance of some patients to antibiotics and the antimicrobial, antioxidant, and curative properties of certain essential oils, we conducted research by incorporating these oils, based on polyvinyl alcohol/ polyvinyl pyrrolidone (PVA/PVP) biopolymers, into dressings. The objective of this study was to study the potential of a polymeric matrix for wound healing, with polyvinyl alcohol as the main material and polyvinyl pyrrolidone and hydroxypropyl methylcellulose (HPMC) as secondary materials, together with additives (plasticizers poly(ethylene glycol) (PEG) and glycerol), stabilizers (Zn stearate), antioxidants (vitamin A and vitamin E), and four types of essential oils (fennel, peppermint, pine, and thyme essential oils). For all the studied samples, the combining compatibility, antimicrobial, and cytotoxicity properties were investigated. The obtained results demonstrated a uniform morphology for almost all the samples and adequate barrier properties for contact with suppurating wounds. The results show that the obtained samples containing essential oils have a good inhibitory effect on, or antimicrobial properties against, Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, and Candida albicans ATCC 10231. The MTT assay showed that the tested samples were not toxic and did not lead to cell death. The results showed that the essential oils used provide an effective solution as active substances in wound dressings.
  • Failure Analysis of Ultra-High Molecular Weight Polyethylene Tibial Insert in Total Knee Arthroplasty
    Veronica Manescu (Paltanea), Iulian Antoniac, Aurora Antoniac, Gheorghe Paltanea, Marian Miculescu, et al.
    Materials, 2022
    Knee osteoarthritis is treated based on total knee arthroplasty (TKA) interventions. The most frequent failure cause identified in surgical practice is due to wear and oxidation processes of the prothesis’ tibial insert. This component is usually manufactured from ultra-high molecular weight polyethylene (UHMWPE). To estimate the clinical complications related to a specific prosthesis design, we investigated four UHMWPE tibial inserts retrieved from patients from Clinical Hospital Colentina, Bucharest, Romania. For the initial analysis of the polyethylene degradation modes, macrophotography was chosen. A light stereomicroscope was used to estimate the structural performance and the implant surface degradation. Scanning electron microscopy confirmed the optical results and fulfilled the computation of the Hood index. The oxidation process in UHMWPE was analyzed based on Fourier-transform infrared spectroscopy (FTIR). The crystallinity degree and the oxidation index were computed in good agreement with the existing standards. Mechanical characterization was conducted based on the small punch test. The elastic modulus, initial peak load, ultimate load, and ultimate displacement were estimated. Based on the aforementioned experimental tests, a variation between 9 and 32 was found in the case of the Hood score. The oxidation index has a value of 1.33 for the reference sample and a maximum of 9.78 for a retrieved sample.
  • Electrochemical and In Vitro Biological Evaluation of Bio-Active Coatings Deposited by Magnetron Sputtering onto Biocompatible Mg-0.8Ca Alloy
    Ana-Iulia Bița, Iulian Antoniac, Marian Miculescu, George E. Stan, Lucia Leonat, et al.
    Materials, 2022
    The use of resorbable magnesium alloys in the design of implants represents a new direction in the healthcare domain. Two main research avenues are currently explored for developing or improving metallic biomaterials: (i) increase of their corrosion resistance by designed compositional and structural modifications, and (ii) functionalization of their surfaces by coating with ceramic or polymeric layers. The main objective of this work was to comparatively assess bio-functional coatings (i.e., highly-crystallized hydroxyapatite and silica-rich glass) deposited by radio-frequency magnetron sputtering (RF-MS) on a biodegradable Mg-0.8Ca alloy (0.8 wt.% of Ca). After probing their morphology (by scanning electron microscopy) and structure (by Fourier transform infrared spectroscopy and grazing incidence X-ray diffraction), the corrosion resistance of the RF-MS coated Mg-0.8Ca substrates was electrochemically tested (in synthetic biological media with different degrees of biomimicry), and their cytocompatibility was assessed in osteoblast and fibroblast cell cultures. By collective assessment, the most promising performances, in terms of mass loss (~7% after 12 days), hydrogen release rate (~6 mL/cm2 after 12 days), electrochemical corrosion parameters and cytocompatibility, were obtained for the crystalline HA coating.
  • Fluoride Treatment and In Vitro Corrosion Behavior of Mg‐Nd‐Y‐Zn‐Zr Alloys Type
    Pham Hong Quan, Iulian Antoniac, Florin Miculescu, Aurora Antoniac, Veronica Manescu (Păltânea), et al.
    Materials, 2022
  • Comparative assessment of in vitro and in vivo biodegradation of Mg-1Ca magnesium alloys for orthopedic applications
    Iulian Antoniac, Răzvan Adam, Ana Biță, Marian Miculescu, Octavian Trante, et al.
    Materials, 2021
  • Comparative framework of calcium phosphates-based products derived from sustainable marine and terrestrial resources for biomedical applications
    Studia Universitatis Babes Bolyai Chemia, 2020
  • Adhesion evaluation of different bioceramic coatings on Mg-Ca alloys for biomedical applications
    Ana-Iulia Bita, G. E. Stan, M. Niculescu, I. Ciuca, E. Vasile, et al.
    Journal of Adhesion Science and Technology, 2016
  • Glass-ceramic coated Mg-Ca alloys for biomedical implant applications
    J.V. Rau, I. Antoniac, M. Fosca, A. De Bonis, A.I. Blajan, et al.
    Materials Science and Engineering C, 2016
  • In vitro degradation and corrosion evaluation of Mg-Ca alloys for biomedical applications
    Journal of Optoelectronics and Advanced Materials, 2016
  • Hydrogen evolution analyzed on various magnesium alloys
    Ana Iulia Bita, Augustin Semenescu, Aurora Antoniac, Iulian Antoniac
    Key Engineering Materials, 2016
  • Influence of antibiotics addition in bone cements for hip arthroplasty on their mechanical properties: Clinical perspective and in vitro tests
    Razvan Ene, Zsombor Panti, Mihai Nica, Marian Pleniceanu, Patricia Ene, et al.
    Key Engineering Materials, 2016
  • Bioceramics and biocomposites from marine sources
    Iulian Vasile Antoniac, Isidoro Giorgio Lesci, Ana Iulia Blajan, Greta Vitioanu, Aurora Antoniac
    Key Engineering Materials, 2015
  • Metallic biomaterials processing technologies in order to obtain a new design for a hip prosthesis femoral component
    Marius Niculescu, Iulian Vasile Antoniac, Ana Blajan
    Solid State Phenomena, 2014
  • Effect of calcium content on the microstructure and degradation of Mg-Ca binary alloys potentially used as orthopedic biomaterials
    Ana Iulia Blajan, Florin Miculescu, Ion Ciucă, Mihai Cosmin Cotruț, Augustin Semenescu, et al.
    Key Engineering Materials, 2014
  • Effect on adhesion to tooth structure for some experimental dental adhesive system
    Loredana Colceriu, Sanda Cimpean, Codruta Nicola, Sorina Sava, Marcela Trif, et al.
    Key Engineering Materials, 2014
  • Failure analysis of some retrieved orthopedic implants based on materials characterization
    Marin Bane, Florin Miculescu, Ana Iulia Blajan, Mihaela Dinu, Iulian Antoniac
    Solid State Phenomena, 2012