FILIPPO MARIA POLLI

Scopus Publications

Predictive factors of long-term dorsal column dysfunction after intramedullary spinal cord tumor resection: a comparative case series
Filippo Maria Polli, Marco Battistelli, Alessandro Rapisarda, Michele Di Domenico, Alessio Albanese, Mario Muselli, Marco Luigetti, Giuseppe Maria Della Pepa, Alessandro Olivi
Journal of Neurosurgery Spine, 2026
OBJECTIVE Postoperative dorsal column dysfunction (DCD) has been observed in 43.6%–55.1% of patients who have undergone surgery for intramedullary spinal cord tumors (IMSCTs). There is a paucity of evidence regarding the prognosticators of its occurrence. The objective of the present study was to ascertain the prognostic factors associated with long-term DCD following IMSCT resection, with a particular emphasis on the role of the myelotomy technique and intraoperative neuromonitoring (IONM). METHODS A case-control study was conducted on consecutive patients. Patients were stratified based on the surgical technique used for midline myelotomy: dorsal column (DC) dissection and preservation technique (group A) and midline coagulation and incision technique (group B). Somatosensory evoked potentials (SSEPs) were categorized as either present or absent. The groups were then analyzed with respect to the Short Form Health Survey 36 (SF-36), the McCormick Scale (MMS), Douleur Neuropathique 4 Questions, and a 3-domain numeric rating scale for investigating DCD, named the Dorsal-Columns Questionnaire (DCQ). Univariate analyses were conducted for MMS and DCQ scores, with data regarding demographics; neurological examination; symptoms; surgery, including extent of resection, tumor histology, tumor location, myelotomy, and tumor extension; hemosiderin cap, cleavage plane presence; and IONM taken into consideration. IONM was recorded at three time points during the surgical procedure: baseline intraoperative, worst intraoperative, and final intraoperative. RESULTS In total, 37 patients were included. Groups A and B had nonsignificantly different demographic parameters. Group A had superior outcomes in MMS (p = 0.002), SF-36 (p = 0.001), and DCQ (p = 0.031) scores at the last follow-up. Group B experienced a significantly higher incidence of worst intraoperative (p = 0.002) and final intraoperative (p = 0.026) SSEP loss. Univariate analysis documented the following major prognostic factors: myelotomy technique (p = 0.012), capillary hemangioma histology (p = 0.045), and worst intraoperative SSEPs (p = 0.034) for the DCQ; myelotomy technique (p < 0.001), intraoperative (p < 0.001) and final intraoperative (p < 0.001) SSEPs, and follow-up bowel-bladder dysfunction (p = 0.02) for the MMS. Final operative SSEPs were not among DCQ prognosticators (p = 0.213). CONCLUSIONS The DC dissection and preservation myelotomy technique is associated with lower long-term DCD and intraoperative SSEP loss and better health-related quality of life and disability when compared with the midline coagulation and incision technique. The myelotomy technique and intraoperative SSEP disappearance, even if transient, are major determinants of long-term disability and DCDs.
Benign or aggressive? Understanding spinal melanocytomas in comparison to malignant melanoma
Alice Ryba, Theresa Mohme, Johannes Kerschbaumer, Emily von Bronewski, Vanessa Hubertus, Vicki M. Butenschoen, Andreas Kramer, Felix C. Stengel, Martin N. Stienen, Marco Battistelli, Filippo Maria Polli, Hanno S. Meyer, Lasse Dührsen, Klaus Christian Mende, Manfred Westphal, Florian Ringel, Bernhard Meyer, Julia Onken, Claudius Thome, Sven O. Eicker, Malte Mohme
Journal of Neuro Oncology, 2026
Introduction Spinal melanocytic tumors are rare, with limited data on their clinical course and aggressiveness. Since intraoperative dark pigmentation and infiltrative margins can lead to misclassification of MC as MM—especially in the absence of a known primary—this multicenter study characterizes melanocytomas (MC) and contrasts them with malignant melanoma (MM). Methods We retrospectively analyzed 56 patients with spinal intradural melanocytic tumors (2010–2024) from seven European neurosurgical centers. Clinical, radiological, histological, and surgical features were analyzed. Univariate and multivariate analyses were performed to identify prognostic risk factors. Results The study included 22 patients with spinal MC and 34 patients with MM. Median age was comparable (61 vs. 58 years, p = 0.09), but MC patients had a longer symptom history (13 vs. 1.3 months, p = 0.0001) and more often intramedullary tumors (72.7% vs. 2.9%, p < 0.0001). Gross total resection was achieved in 40.9% of MC cases and 61.8% of MM cases ( p = 0.07), with instrumentation required more often for MM ( p = 0.0022). Ki-67 proliferation index was significantly higher in MM than MC (26.7% vs. 6.6%, p < 0.0001). Postoperative deficits were more frequent in MC (54.6% vs. 14.7%, p = 0.002) and MCs showed higher frequency of ataxia postoperatively (36.4% vs. 11.8%, p = 0.04). MM patients received more adjuvant therapy (88.2% vs. 31.8%, p = 0.0001), with a trend toward higher local recurrence (26.5% vs. 14.7%, p = 0.31). Conclusion Our study demonstrates that MC, though considered benign, carries a high risk of postoperative deficits. Furthermore, GTR was achieved in only 40% of cases, underscoring its locally infiltrative nature and potential for semi-benign biology.
A visual mining analysis of middle meningeal embolization and other factors associated with recurrence requiring re-operation in subdural hematomas: a single-center series
Marco Battistelli, Marika Vezzoli, Iacopo Valente, Massimo Benenati, Giuseppe Garignano, Andrea Alexandre, Ludovico Agostini, Samuele Santi, Ottavia Giovinazzo, Leonardo Nardini, Federico Costa, Giorgio Quintino D’Alessandris, Manuela D’Ercole, Alessandro Izzo, Alessandro Rapisarda, Francesco Signorelli, Nicola Montano, Simona Gaudino, Alessandro Olivi, Alessandro Pedicelli, Filippo Maria Polli, Francesco Doglietto
Acta Neurochirurgica, 2025
Purpose to comprehensively and hierarchically assess risk factors for recurrence requiring reoperation (RrR) in chronic subdural hematoma (cSDH) in the era of middle meningeal artery embolization (MMAE). Methods Patients treated for a cSDH from January 2019 to October 2024 at Fondazione Gemelli research hospital were considered for inclusion. Clinical, coagulation, radiological, and treatment factors were recorded. MMAE was performed systematically from October 2022, using polyvinyl alcohol (PVA) particles injected directly from the main trunk of MMA. The dataset comprised 45 quantitative and qualitative variables for each cSDH. Variables showing statistical significance (p-value < 0.05) were selected as covariates in two supervised learning frameworks to predict the RrR (outcome, Y ): ( i ) Classification and Regression Tree (CART) and ( ii ) Random Forest (RF) classifier. Results 500 patients were eligible and 233 were included, resulting in 283 treated cSDHs (mean follow-up: 119 days); 129 underwent adjuvant MMAE. 50 cSDH had a RrR (mean time to recurrence: 47 days), of which 41 (82%) in the non-embolized group and 9 (18%) in the embolized group (p-value < 0.001). Adjuvant embolization was the strongest factor associated with RrR, significantly reducing the risk for reintervention. Markwalder grading scale, preoperative cSDH volume, and platelet count (PLT) are strong predictors in non-embolized patients. A critical PLT cut-off of 229 × 10 9 /L strongly impacts RrR risk for substantial cSDH volumes. Conclusions The present results support the routine use of MMAE and the correction of PLT in relation to cSDH volume.
Transthyretin amyloid deposition in the ligamentum flavum of an Italian cohort of patients with lumbar spinal stenosis
Francesca Vitali, Silvia Fenu, Alessandro Izzo, Nicola Montano, Filippo Maria Polli, Alessandro Rapisarda, Francesco Costa, Marco Paolo Schiariti, Marco Gessi, Gianluca Marucci, Giorgio Giaccone, Maria Ausilia Sciarrone, Valeria Guglielmino, Angela Romano, Davide Pareyson, Marco Luigetti
Neurological Sciences, 2025
Bed rest duration and development of cerebrospinal fluid leaks after intradural spinal surgery: a meta-analysis of comparative studies
Alberto BENATO, Fabio ZEOLI, Flavia BECCIA, Marco BATTISTELLI, Alessandro RAPISARDA, Alessandro OLIVI, Filippo M. POLLI
Journal of Cardiovascular Surgery, 2025
INTRODUCTION Postoperative cerebrospinal fluid (CSF) leaks and related complications are a major concern after intradural spinal surgeries. The role of prolonged bed rest in reducing the incidence of these complications has been debated. This meta-analysis aimed to evaluate whether early versus late mobilization affects the incidence of CSF leak-related complications (CLRC) after intradural spinal surgery. EVIDENCE ACQUISITION Following PRISMA guidelines, we conducted a systematic review and meta-analysis of comparative studies on early ambulation (EA) versus prolonged bed rest (PBR) in patients undergoing intradural spinal surgery. Studied considered for inclusion defined EA as mobilization on postoperative day 1, while PBR as mobilization on postoperative day 3. The primary outcome was the incidence of CLRC, defined as pseudomeningocele, durocutaneous fistula, or wound dehiscence. Secondary outcome was the incidence of medical complications. EVIDENCE SYNTHESIS Three retrospective comparative studies with a total of 949 patients were included in the analysis. No significant difference was found in the incidence of CLRC between the EA and PBR groups. Length of hospital stay (LOS) and postoperative medical complications incidence were significantly lower in the EA group. CONCLUSIONS This meta-analysis found that EA does not increase the risk of CLRC compared to PBR, while shortening LOS and reducing medical complications occurrence. These findings suggest that early mobilization could be a safe and effective postoperative strategy, reducing hospital stay and complication rates.
Intraoperative neuromonitorig alert risks in patients submitted to anterior cervical decompression and fusion for cervical spondylotic myelopathy: a single institution cohort-study
Marco Battistelli, Alessandro Rapisarda, Massimo Benenati, Fabio Sbaraglia, Massimiliano Visocchi, Nicola Montano, Martina Taglialatela, Federico Costa, Ignazio Friscia, Michele Di Domenico, Mario Muselli, Giuseppe Maria Della Pepa, Marco Rossi, Simona Gaudino, Francesco Doglietto, Filippo Maria Polli
European Spine Journal, 2025
Purpose To identify positional and intraoperative significant multimodal intraoperative neurophysiological monitoring (mIONM) alert risk factors during anterior cervical surgery in patients with cervical spine myelomalacia. Methods We analyzed prospectively collected data from the PANDA registry between January 2021 and February 2025. Included were patients undergoing anterior cervical decompression and fusion with MRI-confirmed myelomalacia. A significant alert was defined as a ≥ 50% reduction in MEP and/ SSEP amplitude, a ≥ 10% increase in MEP latency, or a spEMG signal. Patients were categorized into three groups: significant warnings at positioning (Group A), during surgical decompression (Group B), and no significant warnings (Group C). Nineteen anamnestic, clinical, radiological, and surgical factors were evaluated. A standardized anesthesia protocol and alert-response strategy were applied. Results Seventy-six patients (132 operated levels) were included. Four patients belonged to Group A and 12 to Group B. Group A exhibited only MEP alerts and showed higher prevalence of peripheral vascular disorders, C3-C4 surgeries, and poorer motor scores in the most affected muscle group; the latter independently predicted alerts with 100% sensitivity at an mMRC threshold of 4. Group B was characterized by only MEP and EMG alerts, significantly longer symptom duration, and myelomalacia spanning two to three levels. Both factors independently predicted intraoperative alerts and were protective when symptom duration was less than 37 months and myelomalacia involved less than two levels. No SSEP alerts occurred. Conclusion These findings support the use of mIONM during positioning and surgical decompression in anterior cervical procedures for patients with cervical myelomalacia, especially in those with segmental motor deficits, prolonged symptoms, and multilevel myelomalacia.
Successful treatment of a C2 aneurysmal bone cyst with hydroxyapatite and calcium sulfate synthetic bone void filler injection: a case report
Marco Battistelli, Alessandro Rapisarda, Nicola Montano, Alessandro Pedicelli, Iacopo Valente, Alessandro Olivi, Filippo Maria Polli
Journal of Spine Surgery, 2024
Background: removal. Non-surgical options include selective arterial embolization (SAE) as main treatment, while Denosumab and centrifugated bone marrow emerge as experimental alternatives. We report a case of C2 ABC in a young woman successfully treated with a single injection of biphasic ceramic bone substitute (BCBS) containing hydroxyapatite (HA) and calcium sulfate. Case Description: resection was deemed unnecessary due to the absence of neurological deficits or deformities, as reported throughout literature evidences. Denosumab administration showed interval tumor change, while SAE was hindered by arterial anastomosis, limiting the possibility of obtaining complete embolization, while significantly increasing cerebral ischemic risks. Repeated intralesional iliac crest bone marrow injection proved ineffective. Subsequently, a single BCBS injection was attempted. A 6-month follow-up computed tomography (CT) scan revealed complete cyst ossification, cortical bone remodeling without artifacts, and spinal canal restoration. Conclusions: HA and calcium sulfate BCBS vertebroplasty emerges as a promising alternative to SAE and denosumab when surgery is not indicated or feasible. Its benefits include effectiveness after a single injection, complete ossification, cortical bone restoration, and artifact-free imaging. These features make it valuable also in cases of pathological fractures.
Unsatisfactory Neurological Outcome in an Intramedullary Thoracic Intermediate-Grade Melanocytoma—Systematic Review and Illustrative Case
Marco Battistelli, Fulvio Grilli, Alessandro Rapisarda, Michele Di Domenico, Nicola Montano, Marco Gessi, Alessandro Olivi, Alessio Albanese, Filippo Maria Polli
Cancers, 2024
Background: Intramedullary melanocytomas are exceedingly rare, with only twenty-four cases reported up to now. They present as local invasive tumors despite their benign biological behavior. Attempting a complete safe resection often results in severe post-operative neurological deficits, as in our case presented here. Methods: A systematic review was conducted across the PubMed and Scopus databases including studies published till February 2024. Results: A total of 19 studies were included, encompassing 24 cases. A similar distribution between sexes was noted (M:F 13:11), with ages ranging from 19 to 79 years. The thoracic segment was most affected, and intermediate-grade melanocytoma (19 cases) was the most common histotype. Radiographically, intramedullary melanocytomas usually appear as hyperintense hemorrhagic lesions peripheral to the central canal with focal nodular enhancement. Intraoperatively, they are black–reddish to tan and are tenaciously adherent lesions. In the sampled studies, IONM employment was uncommon, and post-operative new-onset neurological deficits were described in 16 cases. Adjuvant RT was used in four cases and its value is debatable. Recurrence is common (10 cases), and adjuvant therapies (RT or repeated surgery) seem to play a palliative role. Case presentation: A 68-year-old woman presented with a three-year history of worsening spastic paraparesis and loss of independence in daily activities (McCormick grade 4). An MRI revealed an intramedullary tumor from Th5 to Th7, characterized by T1-weighted hyperintensity and signs of recent intralesional hemorrhage. Multimodal neuromonitoring, comprising the D-Wave, guided the resection of a black–tan-colored tumor with hyper-vascularization and strong adherence to the white matter. During final dissection of the lesion to obtain gross total resection (GTR), a steep decline in MEPs and D-Wave signals was recorded. Post-operatively, the patient had severe hypoesthesia with Th9 level and segmental motor deficits, with some improvement during neurorehabilitation. Histopathology revealed an intermediate-grade melanocytoma (CNS WHO 2021 classification). A four-month follow-up documented the absence of relapse. Conclusions: This literature review highlights that intramedullary T1 hyperintense hemorrhagic thoracic lesions in an adult patient should raise the suspicion of intramedullary melanocytoma. They present as locally aggressive tumors, due to local invasiveness, which often lead to post-operative neurological deficits, and frequent relapses, which overwhelm therapeutic strategies leading to palliative care after several years.
The Role of Psychosomatic Traits in Tailored Workup for Anterior Cervical Discectomy and Fusion—A Case Series
Marco Battistelli, Edoardo Mazzucchi, Mario Muselli, Filippo Maria Polli, Gianluca Galieri, Paola Bazzu, Fabrizio Pignotti, Alessandro Olivi, Giovanni Sabatino, Giuseppe La Rocca
Journal of Personalized Medicine, 2024
Study design: Prospective study. Objective: To evaluate the influence of preoperatively assessed psychosomatic traits on postoperative pain, disability, and quality of life outcomes. Summary of background data: Anterior cervical discectomy and fusion (ACDF) is a widely employed surgical procedure for treating cervical spondylosis. Despite its effectiveness, various studies have reported non-success rates in terms of alleviating disability and pain. Psychological factors have become increasingly recognized as critical determinants of surgical outcomes in various medical disciplines. The full extent of their impact within the context of ACDF remains insufficiently explored. This case series aims to assess the influence of preoperative psychological profiling on long-term pain, disability and quality of life outcomes. Methods: We conducted a prospective cohort study of prospectively collected data from 76 consecutive patients who underwent ACDF with PEEK inter-fixed cages from July 2019 to November 2021. The preoperative psychological traits were assessed using the Symptom Checklist 90 (SCL-90) questionnaire. The Oswestry Disability Index (ODI), Visual Analogue Scale (VAS), Neck Disability index (NDI), EuroQol-5D (EQ-5D), and Short Form-36 (SF-36) were collected preoperatively, one month postoperatively, and at least one year after the surgical procedure. Results: The correlation analyses revealed associations between psychosomatic traits and multiple preoperative and postoperative outcome measures. The univariate analyses and linear regression analyses demonstrated the influence of the Global Severity Index (GSI) over the final follow-up scores for the ODI, VAS, NDI, EQ-5D, and SF-36. The GSI consistently exhibited a stronger correlation with the final follow-up pain, disability, and quality of life outcomes with respect to the correspondent preoperative values. Conclusion: This study highlights the importance of psychosomatic traits as predictive factors for ACDF outcomes and emphasizes their relevance in preoperative assessment for informing patients about realistic expectations. The findings underscore the need to consider psychological profiles in the preoperative workup, opening avenues for research into medications and psychological therapies. Recognizing the influence of psychosocial elements informs treatment strategies, fostering tailored surgical approaches and patient care.
Safety and Efficacy of Zero-Profile Polyetheretherketone (PEEK) Cages Filled with Biphasic Calcium Phosphate (BCP) in Anterior Cervical Discectomy and Fusion (ACDF): A Case Series
Marco Battistelli, Edoardo Mazzucchi, Mario Muselli, Gianluca Galieri, Filippo Maria Polli, Fabrizio Pignotti, Alessandro Olivi, Giovanni Sabatino, Giuseppe La Rocca
Journal of Clinical Medicine, 2024
Background: In the evolving landscape of anterior cervical discectomy and fusion (ACDF), the integration of biomechanical advancements and proper fusion-enhancing materials is crucial for optimizing patient outcomes. This case series evaluates the efficacy and clinical implications of employing zero-profile polyetheretherketone (PEEK) cages filled with biphasic calcium phosphate (BCP) in ACDF procedures, focusing on fusion and subsidence rates alongside patient disability, residual pain, and quality of life. Methods: This case series comprises 76 consecutive patients, with a median follow-up of 581 days. The Bridwell classification system was used for assessing fusion rates while subsidence occurrence was recorded, correlating these radiographic outcomes with clinical implications. Results: The results demonstrated a satisfactory fusion rate (76.4% for grades I and II). The subsidence rate was low (6.74% of segments). Significant clinical improvements were observed in pain, disability, and quality-of-life metrics, aligning with the minimum clinically important difference thresholds; however, subgroup analyses demonstrated that subsidence or pseudoarthrosis group improvement of PROMs was not statistically significant with respect to baseline. ANOVA analyses documented that subsidence has a significant weight over final follow-up pain and disability outcomes. No dysphagia cases were reported. Conclusions: These findings underscore the efficacy of zero-profile PEEK cages filled with BCP in ACDF, highlighting their potential to improve patient outcomes while minimizing complications. Pseudoarthrosis and subsidence have major implications over long-term PROMs. The study reinforces the importance of selecting appropriate surgical materials to enhance the success of ACDF procedures.
Change of Clinical and Radiologic Parameters after Minimally Invasive Decompression in Patients with Lumbar Spinal Stenosis: A Prospective Study with Long-term Follow-up
Giovanni Pennisi, Manuela D'Ercole, Alessandro Izzo, Filippo Maria Polli, Alessandro Rapisarda, Fabio Papacci, Alessandro Olivi, Nicola Montano
Journal of Neurological Surgery Part A Central European Neurosurgery, 2024
The reliability and quality of online patient education videos for vestibular schwannoma
Martina Giordano, Valerio Maria Caccavella, Leonardo Tariciotti, Giuseppe Maria Della Pepa, Alessandro Olivi, Filippo Maria Polli
British Journal of Neurosurgery, 2024
The use of intraoperative CT-neuronavigation in Wiltse approach. A technical note
Marco Battistelli, Federico Valeri, Manuela D’Ercole, Alessandro Izzo, Alessandro Rapisarda, Filippo Maria Polli, Nicola Montano
Frontiers in Surgery, 2024
An Overview of Recent Advances in Anterior Cervical Decompression and Fusion Surgery
, Marco Battistelli, Filippo Maria Polli, , Quintino Giorgio D’Alessandris, , Manuela D’Ercole, , Alessandro Izzo, , Alessandro Rapisarda, , Nicola Montano, and
Surgical Technology International, 2023
Is There a Role for Intraoperative Neuromonitoring in Intradural Extramedullary Spine Tumors? Results and Indications from an Institutional Series
Manuela D’Ercole, Quintino Giorgio D’Alessandris, Michele Di Domenico, Benedetta Burattini, Grazia Menna, Alessandro Izzo, Filippo Maria Polli, Giuseppe Maria Della Pepa, Alessandro Olivi, Nicola Montano
Journal of Personalized Medicine, 2023
Decompression with or without Fusion for Lumbar Synovial Cysts—A Systematic Review and Meta-Analysis
Alberto Benato, Grazia Menna, Alessandro Rapisarda, Filippo Maria Polli, Manuela D’Ercole, Alessandro Izzo, Quintino Giorgio D’Alessandris, Nicola Montano
Journal of Clinical Medicine, 2023
Outcome Comparison of Drug-Resistant Trigeminal Neuralgia Surgical Treatments—An Umbrella Review of Meta-Analyses and Systematic Reviews
Alessandro Rapisarda, Marco Battistelli, Alessandro Izzo, Manuela D’Ercole, Quintino Giorgio D’Alessandris, Filippo Maria Polli, Samuele Santi, Renata Martinelli, Nicola Montano
Brain Sciences, 2023
Atlantoaxial Anterior Transarticular Screw Fixation: Indications and Surgical Technique
Filippo Maria Polli, Alessandro Rapisarda, Sokol Trungu, Stefano Forcato, Nicola Montano, Francesco Signorelli, Massimiliano Visocchi, Alessandro Olivi
Acta Neurochirurgica Supplementum, 2023
Spinal Cord High-Frequency Stimulation. The Current Experience and Future Directions
Alessandro Izzo, Manuela D’Ercole, Alessandro Rapisarda, Filippo Maria Polli, Filomena Fuggetta, Alessandro Olivi, Massimiliano Visocchi, Nicola Montano
Acta Neurochirurgica Supplementum, 2023
Toward the End of the Funnel: The Ventriculus Terminalis—The State of Art of an Ancient Entity with a Recent History
Ginevra Federica D’Onofrio, Alessandro Rapisarda, Francesco Signorelli, Mario Ganau, Salvatore Chibbaro, Nicola Montano, Filippo Maria Polli, Massimiliano Visocchi
Acta Neurochirurgica Supplementum, 2023
Percutaneous Balloon Compression for Trigeminal Neuralgia. A Comparative Study Between the Fluoroscope Guided and Neuronavigated Technique
Manuela D’Ercole, Tommaso Tufo, Alessandro Izzo, Alessandro Rapisarda, Filippo Maria Polli, Francesco Signorelli, Alessandro Olivi, Massimiliano Visocchi, Nicola Montano
Acta Neurochirurgica Supplementum, 2023
Percutaneous pedicle screw fixation without arthrodesis of 368 thoracolumbar fractures: long-term clinical and radiological outcomes in a single institution
Sokol Trungu, Luca Ricciardi, Stefano Forcato, Amadeo Piazza, Giancarlo D’Andrea, Filippo Maria Polli, Marco Cimatti, Alessandro Frati, Massimo Miscusi, Antonino Raco
European Spine Journal, 2023
Spinal Epidural Atypical Meningioma: Case Report and Review of the Literature
Rina di Bonaventura, Valerio Mario Caccavella, Kristy Latour, Alessandro Rapisarda, Marco Gessi, Nicola Montano, Massimiliano Visocchi, Alessandro Olivi, Filippo Maria Polli
Acta Neurochirurgica Supplementum, 2023
Comparison of Effectiveness, Feasibility, Indications, and Limitations of Different Intraoperative Dyes in Spinal Neuro-Oncologic Surgery. A Systematic Review
Pier Paolo Mattogno, Grazia Menna, Giovanni Pennisi, Letizia Corbi, Carmelo Lucio Sturiale, Filippo Maria Polli, Alessandro Olivi, Giuseppe Maria Della Pepa
World Neurosurgery, 2022
Atlantoaxial Joint Distraction and Fusion with DTRAX Intra-Articular Cages: A Cadaveric Feasibility Study and Review of the Pertinent Literature
Alessandro Rapisarda, Giovanni Pennisi, Nicola Montano, Giuseppe Maria Della Pepa, Luca Ricciardi, Fabio De-Giorgio, Massimiliano Visocchi, Alessandro Olivi, Filippo Maria Polli
World Neurosurgery, 2022
Giant Inflammatory Cervical Ganglion Due to Ectopic Rib Head: Report of a Rare Diagnosis Mimicking a Cervical Schwannoma
Alessandro Rapisarda, Omar Ktari, Gessi Marco, Filippo Maria Polli
World Neurosurgery, 2022
Palliative Surgery for Drug-Resistant Epilepsy in Adult Patients. A Systematic Review of the Literature and a Pooled Analysis of Outcomes
Valerio Maria Caccavella, Martina Giordano, Gabriella Colicchio, Alessandro Izzo, Manuela D'Ercole, Alessandro Rapisarda, Filippo Maria Polli, Filomena Fuggetta, Alessandro Olivi, Nicola Montano
World Neurosurgery, 2022
New Tools and Techniques to Prevent CSF Leak in Cranial and Spinal Surgery
Alessandro Rapisarda, , Vittorio Orlando, Alessandro Izzo, Manuela D’Ercole, Filippo Maria Polli, Massimiliano Visocchi, Nicola Montano, , , , , , and
Surgical Technology International, 2022
Clinical Outcomes of Shunting in Normal Pressure Hydrocephalus: A Multicenter Prospective Observational Study
Sokol Trungu, Antonio Scollato, Luca Ricciardi, Stefano Forcato, Filippo Maria Polli, Massimo Miscusi, Antonino Raco
Journal of Clinical Medicine, 2022
Are oral anticoagulants a risk factor for mild traumatic brain injury progression? A single-center experience focused on of direct oral anticoagulants and vitamin K antagonists
Giuseppe Maria Della Pepa, Marcello Covino, Grazia Menna, Anna Maria Auricchio, Filippo Maria Polli, Alberto Manno, Benedetta Simeoni, Alessandro Olivi, Francesco Franceschi
Acta Neurochirurgica, 2022
A systematic review and meta-analysis of factors affecting the outcome of the epidural blood patching in spontaneous intracranial hypotension
Francesco Signorelli, Valerio M. Caccavella, Martina Giordano, Eleonora Ioannoni, Anselmo Caricato, Filippo Maria Polli, Alessandro Olivi, Nicola Montano
Neurosurgical Review, 2021
Comparison between deep brain stimulation and magnetic resonance-guided focused ultrasound in the treatment of essential tremor: A systematic review and pooled analysis of functional outcomes
Martina Giordano, Valerio Maria Caccavella, Ismail Zaed, Livia Foglia Manzillo, Nicola Montano, Alessandro Olivi, Filippo Maria Polli
Journal of Neurology Neurosurgery and Psychiatry, 2020
Hemopatch® with fibrin glue as a dural sealant in cranial and spinal surgery. A technical note with a review of the literature
Nicola Montano, Martina Giordano, Valerio Maria Caccavella, Eleonora Ioannoni, Filippo Maria Polli, Fabio Papacci, Alessandro Olivi
Journal of Clinical Neuroscience, 2020
Lumbar Extraosseous Intraforaminal Osteoblastoma: Case Report and Review of the Literature
Martina Giordano, Valerio Maria Caccavella, Antonio Leone, Nicola Montano, Marco Gessi, Alessandro Olivi, Filippo Maria Polli
World Neurosurgery, 2020
Corrigendum to “Spinal dural tenting sutures in intradural tumor surgery: A technical insight” [J Clin Neurosci 61 (2019) 322–323] (Journal of Clinical Neuroscience (2019) 61 (322–323), (S0967586818315510), (10.1016/j.jocn.2018.10.085))
Alessandro Pesce, Mauro Palmieri, Alessandro Frati, Filippo Maria Polli, Antonino Raco
Journal of Clinical Neuroscience, 2020
X-ray exposure in odontoid screwing for Anderson type II fracture: comparison between O-arm and C-arm-assisted procedures
Luca Ricciardi, Nicola Montano, Ginevra Federica D’Onofrio, Filippo Maria Polli, Marco Latini, Alessandro Bellesi, Fabio Biovi, Alessandro Olivi, Carmelo Lucio Sturiale
Acta Neurochirurgica, 2020
Spinal cordectomy for the management of thoracic malignant intraspinal tumors in paraplegic or irreversibly, severely paraparetic patients: A technical remark
Antonino Raco, Filippo Maria Polli, Mauro Palmieri, Marco Cimatti, Massimo Miscusi, Alessandro Frati, Alessandro Pesce
Journal of Clinical Neuroscience, 2019
The role of non-rigid cervical collar in pain relief and functional restoration after whiplash injury: a systematic review and a pooled analysis of randomized controlled trials
Luca Ricciardi, Vito Stifano, Sonia D’Arrigo, Filippo Maria Polli, Alessandro Olivi, Carmelo Lucio Sturiale
European Spine Journal, 2019
Submandibular Approach for Single-Stage Craniovertebral Junction Ventral Decompression and Stabilization: A Preliminary Cadaveric Study of Technical Feasibility
Luca Ricciardi, Carmelo Lucio Sturiale, Alessandro Izzo, Resi Pucci, Valentino Valentini, Nicola Montano, Filippo Maria Polli, Massimiliano Visocchi, Tito Vivas-Buitrago, Kaisorn L. Chaichana, Alfredo Quinones-Hinojosa, Alessandro Olivi, Selby Chen
World Neurosurgery, 2019
Cervical spine involvement in a challenging case of accidental strangulation
Fabio De-Giorgio, Simone Grassi, Massimo Miscusi, Luca Ricciardi, Filippo Maria Polli
American Journal of Forensic Medicine and Pathology, 2019
Spinal dural tenting sutures in intradural tumor surgery: A technical insight
Alessandro Pesce, Mauro Palmieri, Alessandro Frati, Filippo Maria Polli, Antonino Raco
Journal of Clinical Neuroscience, 2019
Patient-Oriented Aesthetic Outcome After Lumbar Spine Surgery: A 1-Year Follow-Up Prospective Observational Study Comparing Minimally Invasive and Standard Open Procedures
Luca Ricciardi, Carmelo Lucio Sturiale, Resi Pucci, Gabriele Reale, Vito Stifano, Alessandro Izzo, Andrea Perna, Luca Proietti, Stefano Forcato, Krissia M. Rivera Perla, Stefano El Boustany, Alessandro Olivi, Filippo Maria Polli
World Neurosurgery, 2019
One Center's Experience with Hybrid Technique for Lumbar Spine Instrumentated Surgeries: Evaluation of Different Instrumentation Systems and Their Management
Luca Ricciardi, Vito Stifano, Krissia Margarita Rivera Perla, Giuseppe Maria Della Pepa, Alessandro Izzo, Giuseppe La Rocca, Giovanni Sabatino, Alessandro Olivi, Filippo Maria Polli
World Neurosurgery, 2018
Use of Neuronavigation System for Superficial Vein Identification: Safe and Quick Method to Avoid Intraoperative Bleeding and Vein Closure: Technical Note
Luca Ricciardi, Giuseppe Maria Della Pepa, Alessandro Izzo, Giorgia Antonia Simboli, Filippo Maria Polli, Giuseppe La Rocca, Giovanni Sabatino
World Neurosurgery, 2018
Intraoperative and Postoperative Segmental Lordosis Mismatch: Analysis of 3 Fusion Techniques
Luca Ricciardi, Vito Stifano, Luca Proietti, Andrea Perna, Giuseppe Maria Della Pepa, Giuseppe La Rocca, Alessandro Olivi, Filippo Maria Polli
World Neurosurgery, 2018
Real-time intraoperative contrast-enhanced ultrasound (CEUS) in vascularized spinal tumors: a technical note
Giuseppe Maria Della Pepa, Pier Paolo Mattogno, Giuseppe La Rocca, Giovanni Sabatino, Alessandro Olivi, Luca Ricciardi, Filippo Maria Polli
Acta Neurochirurgica, 2018
Risk of Postoperative Performance Status Worsening after Resection of Lesions Involving the Motor Pathway: A Multinomial Logistic Regression Model
Alessandro Pesce, Flavia Fraschetti, Giancarlo D'Andrea, Filippo Polli, Michele Acqui, Alessandro Frati, Antonino Raco
Journal of Neurological Surgery Part A Central European Neurosurgery, 2018
Long-term Clinical Outcomes and Quality of Life in Elderly Patients Treated with Interspinous Devices for Lumbar Spinal Stenosis
Massimo Miscusi, Stefano Forcato, Alessandro Ramieri, Filippo Polli, Antonino Raco, Sokol Trungu
Journal of Neurological Surgery Part A Central European Neurosurgery, 2018
Atlantoaxial joint distraction with a new expandable device for the treatment of basilar invagination with preservation of the C2 nerve root: A cadaveric anatomical study
Filippo Maria Polli, Sokol Trungu, Massimo Miscusi, Stefano Forcato, Massimiliano Visocchi, Antonino Raco
Acta Neurochirurgica Supplementum, 2017
Comparison of minimally invasive surgery with standard open surgery for vertebral thoracic metastases causing acute myelopathy in patients with short- or mid-term life expectancy: Surgical technique and early clinical results
Massimo Miscusi, Filippo Maria Polli, Stefano Forcato, Luca Ricciardi, Alessandro Frati, Marco Cimatti, Luca De Martino, Alessandro Ramieri, Antonino Raco
Journal of Neurosurgery Spine, 2015
Cardiopulmonary cement embolism after vertebroplasty
Filippo Maria Polli, Alessandra Marongiu, Massimo Miscusi, Fabio De-Giorgio, Antonino Raco
Spine Journal, 2015
Atlantoaxial anterior transarticular screw fixation: A case series and reappraisal of the technique
Filippo Maria Polli, Massimo Miscusi, Stefano Forcato, Antonino Raco
Spine Journal, 2015
The use of surgical sealants in the repair of dural tears during non-instrumented spinal surgery
Massimo Miscusi, Filippo Maria Polli, Stefano Forcato, Maria Antoaneta Coman, Luca Ricciardi, Alessandro Ramieri, Antonino Raco
European Spine Journal, 2014
Unusual complication of condrocostal implant in rhinoplasty
Evaristo Belli, Pasquale Virciglio, Giuseppina Fini, Elidon Mici, Filippo Maria Polli
Journal of Craniofacial Surgery, 2014
Pure percutaneous pedicle screw fixation without arthrodesis of 32 thoraco-lumbar fractures: Clinical and radiological outcome with 36-month follow-up
Marco Cimatti, Stefano Forcato, Filippo Polli, Massimo Miscusi, Alessandro Frati, Antonino Raco
European Spine Journal, 2013
Symptomatic ganglion cyst of ligamentum flavum as a late complication of lumbar fixation
Massimo Miscusi, Vincenzo Petrozza, Filippo Maria Polli, Stefano Forcato, Carlo Della Rocca, Antonino Raco
Neurologia I Neurochirurgia Polska, 2012
Spondylectomy of T-2 according to the Tomita technique via an extended Fessler approach: a cadaveric study - Laboratory investigation
Massimo Miscusi, Maurizio Domenicucci, Filippo Maria Polli, Stefano Forcato, Fabio De Giorgio, Antonino Raco
Journal of Neurosurgery Spine, 2012
Restoration of sexual activity in patients with chronic hydrocephalus after shunt placement
Paolo Missori, Antonio Scollato, Rita Formisano, Antonio Currà, Concetta Mina, Massimo Marianetti, Filippo Maria Polli, Simone Peschillo, Sergio Paolini, Alessandro Frati, Massimo Miscusi
Acta Neurochirurgica, 2009
Neurocytoma of the spinal cord: Report of three cases and review of the literature
Filippo Maria Polli, Maurizio Salvati, Massimo Miscusi, Roberto Delfini, Felice Giangaspero
Acta Neurochirurgica, 2009
Improved epilepsy after surgical decompression of the internal carotid artery in a patient with spheno-clinoidal meningioma
Bollettino Lega Italiana Contro L Epilessia, 2008
Double dural patch in decompressive craniectomy to preserve the temporal muscle: technical note
Paolo Missori, Filippo Maria Polli, Simone Peschillo, Elena D'Avella, Sergio Paolini, Massimo Miscusi
Surgical Neurology, 2008
Does recurrent laryngeal nerve anatomy condition the choice of the side for approaching the anterior cervical spine?
Journal of Neurosurgical Sciences, 2007
Magnetic resonance imaging flow void changes after cerebrospinal fluid shunt in post-traumatic hydrocephalus: Clinical correlations and outcome
Paolo Missori, Massimo Miscusi, Rita Formisano, Simone Peschillo, Filippo M. Polli, Antonio Melone, Stefano Martini, Sergio Paolini, Roberto Delfini
Neurosurgical Review, 2006
Ghost lesions in patient with cerebral-isolated neurosarcoidosis: A case report
Journal of Neurosurgical Sciences, 2006
Idiopathic normal-pressure hydrocephalus.
Massimo Marianetti, Concetta Mina, Massimo Miscusi, Filippo Maria Polli, Paolo Missori
Journal of Neurosurgery, 2006
Surgical approaches to the cervico-thoracic junction
Journal of Neurosurgical Sciences, 2005
Progressive quadriparesis in adolescent with stenosis of the cervical spine
P. Missori, F. M. Polli, R. Delfini
Child S Nervous System, 2003
Ethylene oxide sterilization of autologous bone flaps following decompressive craniectomy
P. Missori, F. M. Polli, E. Rastelli, P. Baiocchi, S. Artizzu, G. Rocchi, M. Salvati, S. Paolini, R. Delfini
Acta Neurochirurgica, 2003
Closure of skin or scalp with absorbable sutures [12]
Paolo Missori, Filippo Maria Polli, Elena Fontana, Roberto Delfini
Plastic and Reconstructive Surgery, 2003
Radiation-induced gliomas: Report of 10 cases and review of the literature
Maurizio Salvati, Alessandro Frati, Natale Russo, Emanuela Caroli, Filippo Maria Polli, Giuseppe Minniti, Roberto Delfini
Surgical Neurology, 2003
Radiation-induced schwannomas of the nervous system: Report of five cases and review of the literature
Journal of Neurosurgical Sciences, 2003
Glioblastoma in kidney transplant recipients. Report of five cases
Maurizio Salvati, Alessandro Frati, Emanuela Caroli, Natale Russo, Filippo M. Polli, Maurizio Domenicucci, Roberto Delfini
Journal of Neuro Oncology, 2003
Reconstruction of suboccipital craniectomy with autologous bone chips
P. Missori, E. Rastelli, F. Maria Polli, R. Tarantino, G. Rocchi, R. Delfini
Acta Neurochirurgica, 2002
Intraparenchymal haemorrhage after evacuation of chronic subdural haematoma. Report of three cases and review of the literature
P. Missori, M. Salvati, F. M. Polli, V. Conserva, R. Delfini
British Journal of Neurosurgery, 2002
Surgical approaches to tumours of the lateral ventricles in the dominant hemisphere
Journal of Neurosurgical Sciences, 2002

FILIPPO MARIA POLLI

RESEARCH INTERESTS

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Scopus Publications

FILIPPO MARIA POLLI

RESEARCH INTERESTS

FUTURE PROJECTS

The crosstalk between the epigenome and mitochondria as a novel therapeutic target to counteract remote degeneration induced by spinal cord injury

Scopus Publications