Uche Basil Eke a Fellow of the Chemical Society of Nigeria (FCSN), is a Professor of inorganic chemistry in the Department of Chemistry, Faculty of Physical Sciences, University of Ilorin, Ilorin with over three decades of teaching, research and administrative experience. He has served the University of Ilorin in different capacities including Head of Department of Chemistry, Dean of Faculty of Physical Sciences and Chairman, University Sports Council.
His areas of research interests include Biofuels, Biopolymer Conjugates of drug candidates, Chemistry for Healthy Life. Professor Eke has successfully supervised 10 PhDs and more than 20 Masters’ theses in the area of Biofuels and Biopolymer Conjugates of drug candidates. He has successfully produced and optimized performance parameters of a new biodiesel. He has also published over forty-five research papers in high impact factor peer-reviewed scientific journals. He has a book on renewable energy published by Lambert Academic Publisher
EDUCATION
BSc., MSc. PhD. Chemistry
RESEARCH, TEACHING, or OTHER INTERESTS
Inorganic Chemistry, Renewable Energy, Sustainability and the Environment, General Agricultural and Biological Sciences
20
Scopus Publications
281
Scholar Citations
11
Scholar h-index
13
Scholar i10-index
Scopus Publications
Synthesis, Characterization, and Antimicrobial Studies of Some Metal (II) Complexes of Some Azo Dyes Asean Journal for Science and Engineering in Materials, 2023
Synthesis, characterisation and in vitro anticancer activity of catalytically active indole-based half-sandwich complexes Joan J. Soldevila-Barreda, Kehinde B. Fawibe, Maria Azmanova, Laia Rafols, Anaïs Pitto-Barry, Uche B. Eke, Nicolas P. E. Barry Molecules, 2020 The synthesis, characterisation and evaluation of the in vitro cytotoxicity of four indole-based half-sandwich metal complexes towards two ovarian cancer cell lines (A2780 and A2780cisR) and one normal prostate cell line (PNT2) are presented herein. Although capable of inducing catalytic oxidation of NADH and able to reduce NAD+ with high turnover frequencies, in cells and in the presence of sodium formate, these complexes also strongly interact with biomolecules such as glutathione. This work highlights that efficient out-of-cells catalytic activity might lead to higher reactivity towards biomolecules, thus inhibiting the in-cells catalytic processes.
Synthesis of new ruthenium(II) complexes derived from labile nitrile ligands: an alternative route to the preparation of trans-dichlorotetrakis(diphenylphosphine)ruthenium(II) Samson O. Owalude, Adedibu C. Tella, Ezekiel O. Odebunmi, Uche B. Eke, James E. Golen, Arnold L. Rheingold, Thabo Joel Mahlaka, Reinout Meijboom Journal of Coordination Chemistry, 2017 New ruthenium(II) complexes containing labile nitrile ligands have been prepared by treatment of either the polymer [{RuCl2(COD)}x] (COD = cycloocta-1,5-diene) (1) or its derivative [RuCl2(COD)(NCCH3)2]·NCCH3 (2) with the appropriate nitrile ligands in refluxing acetonitrile under argon. A new route to synthesis of trans-dichlorotetrakis(diphenylphosphine)ruthenium(II) (7) was also reported. A redetermination of the structure of 7 was undertaken and X-ray crystallographic data revealed that the complex crystallizes in the triclinic space group P-1 with unit cell dimensions a = 12.7016(9) Å, b = 13.0847(10) Å, c = 14.1498(10) Å, α = 101.46(3)°, V = 2080.6(3) Å3, Z = 2 and R = 0.0309. Its polymorph 7′ was also obtained. The crystal structure of 4 was also determined. This complex crystallizes in the monoclinic space group C2/c with unit cell dimensions a = 27.0510(3) Å, b = 11.0984(13) Å, c = 13.0450(16) Å, α = 90°, V = 3886.5(8) Å3, Z = 8 and R = 0.0282.
Solvent-free mechanochemical synthesis and X-ray studies of Cu(II) and Ni(II) complexes of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine (Trimethoprim) in a ball-mill Adedibu C. Tella, Uche B. Eke, Samson O. Owalude Journal of Saudi Chemical Society, 2016 Solvent-free synthesis of [Cu(CH3COO)2(TMP)2](1) and [Ni(CH3COO)2(TMP)2](2) by ball milling of Cu(CH3COO)2.H2O and Ni(CH3COO)2.4H2O with Trimethoprim in the absence of solvent is described. Conventional synthesis of 1. CH3OH and 2. CH3OH was carried out by the reaction of metal acetate salt and Trimethoprim using the solution-based method (reflux in CH3OH for 2 h) for comparison purposes. The mechanochemical products were characterized by comparison of melting points, conductivity values, spectral data, XRPD patterns with those of free ligand and solution based conventional synthesis products. X-ray diffraction patterns of the complex were similar to the simulated pattern of the complex obtained from single crystal structure suggesting the formation of identical compounds as obtained in solvent medium. The process presented here is operationally simple, environmentally benign and affords excellent yields without the need for solvents or external heating. Clearly, it can present a higher efficiency in terms of materials, energy and time compared to classical solution phase synthesis.
Spectral studies of transition metal complexes of dihydrobis(1-pyrazoyl)borate with some Lewis bases Adediran M. Mesubi, Uche B. Eke, Oyedele M. Oyeku, Samson O. Owalude Journal of Taibah University for Science, 2016 Co(II), Ni(II) and Cu(II) complexes of dihydrobis(1-pyrazolyl)borate and their adducts with some Lewis bases have been prepared and characterized by elemental analyses, IR and UV–vis spectroscopic techniques. The adducts were either 1:1 or 1:2 complexes depending on whether the Lewis base was bidentate or monodentate. The results indicate that adducts with 1,10-phenanthroline were the most stable due to the chelating effect of the Lewis base. The order of reactivity of the complexes was determined to be Ni(H2BPz2)2 > Cu(H2BPz2)2 > CoH2(BPz2)2 > Co(H2BPz2)2. The effects of various solvents (i.e., benzene, chloroform and DMF) on the structure were studied. The solvents appear to minimally affect the visible spectra of Co(H2BPz2)2. The Ni(H2BPz2)2 and Cu(H2BPz2)2 adducts exhibit a four-coordinate structure in non-coordinating solvents. However, in coordinating solvents, such as DMF, the adducts exhibit six-coordinate structures.
The synthesis and structure of hexakis(dimethylphenylphosphonite) ruthenium(ii) bis[tetraphenylborate(-1)] Samson O. Owalude, Ezekiel O. Odebunmi, Uche B. Eke, Adedibu C. Tella, Arnold L. Rheingold, Steven L. Suib Zeitschrift Fur Anorganische Und Allgemeine Chemie, 2014 Treatment of the hydrazine salt [Ru(COD)(H2NNH2)4][BPh4]2 with excess of P(OMe)2Ph in acetone gave a homoleptic complex trans-[Ru{P(OMe)2Ph}6][BPh4]2, which was characterized by IR, 31P{1H}, 13C{1H}, and 1H NMR spectroscopy, elemental analysis, and X-ray crystallography. The ruthenium in the complex has distorted octahedral coordination arrangement and bonded to all the six P(OMe)2Ph molecules through the phosphorus atoms.
Synthesis and X-ray studies of ruthenium(ii) complexes containing hydrazine and benzyl isocyanide ligands S.O. Owalude, E.O. Odebunmi, U.B. Eke, R. Meijboom, V.N. Nesterov, E. Singleton, N.J. Coville Bulletin of the Chemical Society of Ethiopia, 2013 The reaction of the polymeric species [{RuCl 2 (COD)} x ] ( 1 ; x > 2; COD = cyclo-octa-1,5-diene) and hydrazine hydrate in methanol under reflux gave a pale pink solution from which the salt [Ru(COD)(N 2 H 4 ) 4 ][BPh 4 ] 2 .CH 3 OH ( 2 ) was isolated on addition of NaBPh 4 . Treatment of 2 in refluxing acetone in the presence of the ligand benzyl isocyanide give a complex of stoichiometry [Ru(NH 2 N=CMe 2 ) 2 (PhCH 2 NC) 4 ][BPh 4 ] 2 ( 3 ) on the substitution of the labile COD ligand. The two compounds have been characterized by elemental analyses, IR and NMR measurements and single-crystal X-ray diffraction studies. The ruthenium in both compounds has a distorted octahedral coordination geometry. KEY WORDS : Cycloocta-1,5-diene, Hydrazine hydrate, Isocyanide, Ruthenium Bull. Chem. Soc. Ethiop. 2013 , 27(3), 405-411. DOI: http://dx.doi.org/10.4314/bcse.v27i3.9
The solid-state isomerization of cis-and Olalere G Adeyemi, Manuel A Fernandes, Lin Cheng, Uche B Eke, Demetrius C Levendis, Neil J Coville Comptes Rendus Chimie, 2002
Synthesis and Morphological Studies of Cellulose and Cellobiose Conjugates of Para-Aminobenzoic Acid Hydrazide Using Scanning Electron Microscopy (SEM) AO Ebune, AU Atumeyi, NM Bello, SO Owalude, UB Eke International Journal of Research and Scientific Innovation (IJRSI) 13 (3) , 2026 2026
Process Optimization of Solvent-Free Transesterification of Palm Kernel Oil for Biodiesel Production UB Eke, LI Alhaji, S Degni, SO Owalude, AO Michael, FO Nwosu, ... Journal of Pure and Applied Sciences (Science Forum) 26 (1) , 2026 2026
CARBON MONOXIDE RELEASING TUNGSTEN TRICARBONYL COMPLEXES WITH ANTIBACTERIAL ACTIVITY TA Abubakar, UB Eke, KO Gabriel, S Ali Bayero Journal of Pure and Applied Sciences 14 (1), 75-82 , 2023 2023
Synthesis, characterization, and antimicrobial studies of some metal (II) complexes of some azo dyes RC Aladesusi, UB Eke ASEAN Journal for Science and Engineering in Materials 2 (2), 109-118 , 2023 2023 Citations: 5
The facile synthesis of cationic Ru (II)-hydrazine and hydrazone complexes containing ethyldiphenylphosphine and methyldiphenylarsine ligands SO Owalude, VO Adimula, AC Tella, UB Eke Bayero Journal of Pure and Applied Sciences 15 (1), 147-151 , 2022 2022 Citations: 1
Bioorganometallic ferroquine and related compounds as antimalarial chemotherapeutic agents: a short review TA Abubakar, UB Eke, A Salisu Journal of Chemical Society of Nigeria 47 (3) , 2022 2022 Citations: 4
Morpholigical and Molecular Docking Studies on the Fortification of Starch from Maize with Isolated and Characterized Defatted Soybean Globulins Powder UB Eke, OK Yusuff, SK Degni, OO Enietan Journal of Chemical Society of Nigeria 46 (6) , 2021 2021
PREPARATION, CHARACTERIZATION AND ANTIBACTERIAL STUDIES OF HYDRAZONE SUBSTITUTED MOLYBDENUM CARBONYLS TA Abubakar, UB Eke Journal of Chemical Society of Nigeria 46 (5) , 2021 2021 Citations: 1
Synthesis, characterisation and in vitro anticancer activity of catalytically active indole-based half-sandwich complexes JJ Soldevila-Barreda, KB Fawibe, M Azmanova, L Rafols, A Pitto-Barry, ... Molecules 25 (19), 4540 , 2020 2020 Citations: 28
Organometallic-tamoxifen hybrids: a chronology of the search for new selective estrogen receptor modulator TA Abubakar, UB Eke Journal of Chemical Society of Nigeria 45 (2) , 2020 2020 Citations: 2
Isoniazid stabilized tungsten tricarbonyl complex: A new CO-releasing molecule with antibacterial activity TA Abubakar, UB Eke, DK Sylvestre Sci. Forum (J. Pure Appl. Sci.) 19, 139-144 , 2020 2020 Citations: 3
Degradation studies of methylene blue on the surface of zinc oxide composite of cellulose SK Degni, UB Eke, TO Amusan, TA Abubakar International Journal of Photochemistry 5 (1), 11-22 , 2019 2019 Citations: 1
Isolation and Stability Studies of Dried Protein Fractions from Three Leguminous Seeds: Glycine max, Vignaunguiculata and Parkiabiglobasa SK Degni, UB Eke, HB Omowumi International Journal of Agrochemistry 5 (1), 28-40 , 2019 2019 Citations: 1
A new heterobimetallic ruthenium (II) complex: synthesis, spectral studies and catalytic activity potential in the transfer hydrogenation of ketones SO Owalude, AC Tella, UB Eke, EO Odebunmi Journal of Chemical Society of Nigeria 44 (1) , 2019 2019
A New Multidentate Fluorescent Chemosensor for Metal Ions: Synthesis and Fluorescence Response SK Degni, UB Eke, TA Abubakar IJEC 10, 17 , 2019 2019
Transesterification Reaction of Palm Kernel Oil (PKO) on a Bed of Crushed Cashew Nut Shell (CCNS) UB Eke, SO Owalude, AC Tella, OG Adejoro Nigerian Journal of Basic and Applied Sciences 27 (1), 41-47 , 2019 2019
Synthesis of new ruthenium (II) complexes containing isocyanide and labile nitrile ligands SO Owalude, AC Tella, UB Eke, EO Odebunmi Nigerian Journal of Chemical Research 22 (1), 70-77 , 2017 2017
Trimethylamine N-oxide promoted decarbonylation reactions of molybdenum and tungsten hexacarbonyls with dimethylglyoxime AT Abubakar, UB Eke ChemSearch Journal 8 (1), 29-33 , 2017 2017 Citations: 1
Synthesis and characterization of substituted Mo and W carbonyl complexes containing some biologically active ancillary ligands. TA Abubakar, UB Eke JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 22, S53-S53 , 2017 2017
Stability constant of some Anti-Tuberculosis metal drug complexes MO Bamigboye, UB Eke, JA Obaleye, HF Babamale Ilorin Journal of Science 4 (1), 174–181-174–181 , 2017 2017
MOST CITED SCHOLAR PUBLICATIONS
Synthesis, characterisation and in vitro anticancer activity of catalytically active indole-based half-sandwich complexes JJ Soldevila-Barreda, KB Fawibe, M Azmanova, L Rafols, A Pitto-Barry, ... Molecules 25 (19), 4540 , 2020 2020 Citations: 28
Mechanically-induced solvent-less synthesis of cobalt and nickel complexes of cimetidine C Tella Orbital-The Electronic… , 2011 2011 Citations: 24
Synthesis of heterobimetallic complexes from (. eta. 4-MeC5H5) Fe (CO) 2 (. eta. 1-PPh2CH2PPh2) LK Liu, LS Luh, YS Wen, UB Eke, MA Mesubi Organometallics 14 (10), 4474-4482 , 1995 1995 Citations: 20
Synthesis, structural and biocidal activity studies of triorganotin(IV) compounds of some N ‐protected amino‐acids MA Mesubi, UB Eke, TT Bamgboye Applied Organometallic Chemistry 2 (2), 121-127 , 1988 1988 Citations: 19
Synthesis of Half-Sandwich Iron Carboxyalkyls and Iron (Thiocarboxy) alkyls: Reaction of Cyclopentadienyldicarbonyliodoiron with O-and S-Based Nucleophiles in the Presence of … LK Liu, UB Eke, MA Mesubi Organometallics 14 (8), 3958-3962 , 1995 1995 Citations: 17
Solvent-free synthesis, X-ray studies and in vitro inhibitory activities of copper (II) complexes of non-steroidal anti-inflammatory drugs AC Tella, JA Obaleye, UB Eke, AY Isaac, OM Ameen Research on Chemical Intermediates 40 (4), 1441-1457 , 2014 2014 Citations: 15
Cyclopentadienyldicarbonyliron Halides as Electrophiles: Reactions of (. eta. 5-C5H5) Fe (CO) 2I with MeLi in the Presence of Monophosphines and Diphosphines LS Luh, UB Eke, LK Liu Organometallics 14 (1), 440-447 , 1995 1995 Citations: 14
Solvent-free mechanochemical synthesis and X-ray studies of Cu (II) and Ni (II) complexes of 5-(3, 4, 5-Trimethoxybenzyl) pyrimidine-2, 4-diamine (Trimethoprim) in a ball-mill AC Tella, UB Eke, SO Owalude Journal of Saudi Chemical Society 20, S376-S381 , 2016 2016 Citations: 13
Syntheses and X-ray crystal structures of two ruthenium (II) complexes derived from acetonitrile and dimethylphenylphosphonite SO Owalude, EO Odebunmi, UB Eke, AL Rheingold, N Opembe, SL Suib Journal of Organometallic Chemistry 739, 21-25 , 2013 2013 Citations: 12
Solid-state isomerisation reactions of (η5-C5H4R) M (CO) 2 (PR3′) I (M= W, Mo; R= tBu, Me; R′= Ph, OiPr3) OG Adeyemi, UB Eke, L Cheng, LM Cook, DG Billing, BB Mamba, ... Journal of organometallic chemistry 689 (13), 2207-2215 , 2004 2004 Citations: 12
Bis (acetonitrile-κN) dichlorido (η4-cycloocta-1, 5-diene) ruthenium (II) acetonitrile monosolvate H Chiririwa, R Meijboom, SO Owalude, UB Eke, C Arderne Structure Reports 67 (8), m1096-m1096 , 2011 2011 Citations: 11
Enrichment of a cassava meal (Gari) with soyabean protein extract UB Eke, SO Owalude, LA Usman Adv. Nat. Appl. Sci 2, 60-62 , 2008 2008 Citations: 11
Spectral studies of transition metal complexes of dihydrobis (1-pyrazoyl) borate with some Lewis bases AM Mesubi, UB Eke, OM Oyeku, SO Owalude Journal of Taibah University for Science 10 (1), 70-79 , 2016 2016 Citations: 10
MeLi Reactions with the Electrophile System of (η 5 -C 5 H 5 )Fe(CO) 2 I/P(OMe) 3 : The Roles of MeLi as Reductant, Nucleophile, and Base LK Liu, YH Liao, UB Eke Organometallics 18 (7), 1154-1158 , 1999 1999 Citations: 9
Synthesis and X-ray studies of ruthenium (II) complexes containing hydrazine and benzyl isocyanide ligands SO Owalude, EO Odebunmi, UB Eke, R Meijboom, VN Nesterov, ... Bulletin of the Chemical Society of Ethiopia 27 (3), 405-411 , 2013 2013 Citations: 7
The solid-state isomerization of cis - and trans -(η 5 -C 5 H 4 Me)Mo(CO) 2 (P(O i Pr) 3 )I OG Adeyemi, MA Fernandes, L Cheng, UB Eke, DC Levendis, NJ Coville Comptes rendus. Chimie 5 (5), 387-394 , 2002 2002 Citations: 7
Stoichiometric vs Catalytic MeLi Reaction with the Mixture of (eta^ 5-C~ 5H~ 5) Fe (CO)~ 2I and P (OR)~ 3: Nucleophilic Methylation vs Arbuzov-like Dealkylation UB Eke, L Yi-Hsien, W Yuh-Sheng, L Ling-Kang JOURNAL-CHINESE CHEMICAL SOCIETY TAIPEI 47 (1), 109-116 , 2000 2000 Citations: 7
Synthesis, characterization, and antimicrobial studies of some metal (II) complexes of some azo dyes RC Aladesusi, UB Eke ASEAN Journal for Science and Engineering in Materials 2 (2), 109-118 , 2023 2023 Citations: 5
Synthesis of new ruthenium(II) complexes derived from labile nitrile ligands: an alternative route to the preparation of trans -dichlorotetrakis(diphenylphosphine … SO Owalude, AC Tella, EO Odebunmi, UB Eke, JE Golen, AL Rheingold, ... Journal of Coordination Chemistry 70 (7), 1260-1269 , 2017 2017 Citations: 5
Bioorganometallic compounds in medicine: The search for new antibacterial agents UB Eke, TA Abubakar World Journal of Biomedicine and Pharmaceutical Sciences 1 (1), 22-27 , 2015 2015 Citations: 5
