Amy Garner

@imperial.ac.uk

Clinical Research Fellow, MSK Lab
Imperial College London



              

https://researchid.co/amygarner

RESEARCH, TEACHING, or OTHER INTERESTS

Orthopedics and Sports Medicine

17

Scopus Publications

Scopus Publications

  • Load transfer in bone after partial, multi-compartmental, and total knee arthroplasty
    Jennifer C. Stoddart, Amy Garner, Mahmut Tuncer, Andrew A. Amis, Justin Cobb, and Richard J. van Arkel

    Frontiers Media SA
    Introduction: Arthroplasty-associated bone loss remains a clinical problem: stiff metallic implants disrupt load transfer to bone and, hence, its remodeling stimulus. The aim of this research was to analyze how load transfer to bone is affected by different forms of knee arthroplasty: isolated partial knee arthroplasty (PKA), compartmental arthroplasty [combined partial knee arthroplasty (CPKA), two or more PKAs in the same knee], and total knee arthroplasty (TKA).Methods: An experimentally validated subject-specific finite element model was analyzed native and with medial unicondylar, lateral unicondylar, patellofemoral, bi-unicondylar, medial bicompartmental, lateral bicompartmental, tricompartmental, and total knee arthroplasty. Three load cases were simulated for each: gait, stair ascent, and sit-to-stand. Strain shielding and overstraining were calculated from the differences between the native and implanted states.Results: For gait, the TKA femoral component led to mean strain shielding (30%) more than three times higher than that of PKA (4%–7%) and CPKA (5%–8%). Overstraining was predicted in the proximal tibia (TKA 21%; PKA/CPKA 0%–6%). The variance in the distribution for TKA was an order of magnitude greater than for PKA/CPKA, indicating less physiological load transfer. Only the TKA-implanted femur was sensitive to the load case: for stair ascent and gait, almost the entire distal femur was strain-shielded, whereas during sit-to-stand, the posterior femoral condyles were overstrained.Discussion: TKA requires more bone resection than PKA and CPKA. These finite element analyses suggest that a longer-term benefit for bone is probable as partial and multi-compartmental knee procedures lead to more natural load transfer compared to TKA. High-flexion activity following TKA may be protective of posterior condyle bone resorption, which may help explain why bone loss affects some patients more than others. The male and female bone models used for this research are provided open access to facilitate future research elsewhere.

  • Metabolic equivalent of task scores avoid the ceiling effect observed with conventional patient-reported outcome scores following knee arthroplasty
    Arjun Patel, Thomas C. Edwards, Gareth Jones, Alexander D. Liddle, Justin Cobb, and Amy Garner

    British Editorial Society of Bone & Joint Surgery
    AimsThe metabolic equivalent of task (MET) score examines patient performance in relation to energy expenditure before and after knee arthroplasty. This study assesses its use in a knee arthroplasty population in comparison with the widely used Oxford Knee Score (OKS) and EuroQol five-dimension index (EQ-5D), which are reported to be limited by ceiling effects.MethodsA total of 116 patients with OKS, EQ-5D, and MET scores before, and at least six months following, unilateral primary knee arthroplasty were identified from a database. Procedures were performed by a single surgeon between 2014 and 2019 consecutively. Scores were analyzed for normality, skewness, kurtosis, and the presence of ceiling/floor effects. Concurrent validity between the MET score, OKS, and EQ-5D was assessed using Spearman’s rank.ResultsPostoperatively the OKS and EQ-5D demonstrated negative skews in distribution, with high kurtosis at six months and one year. The OKS demonstrated a ceiling effect at one year (15.7%) postoperatively. The EQ-5D demonstrated a ceiling effect at six months (30.2%) and one year (39.8%) postoperatively. The MET score did not demonstrate a skewed distribution or ceiling effect either at six months or one year postoperatively. Weak-moderate correlations were noted between the MET score and conventional scores at six months and one year postoperatively.ConclusionIn contrast to the OKS and EQ-5D, the MET score was normally distributed postoperatively with no ceiling effect. It is worth consideration as an arthroplasty outcome measure, particularly for patients with high expectations.Cite this article: Bone Jt Open 2023;4(3):129–137.

  • Medial bicompartmental arthroplasty patients display more normal gait and improved satisfaction, compared to matched total knee arthroplasty patients
    Amy J. Garner, Oliver W. Dandridge, Richard J. van Arkel, and Justin P. Cobb

    Springer Science and Business Media LLC
    Abstract Purpose Medial bicompartmental arthroplasty, the combination of ipsilateral medial unicompartmental and patellofemoral arthroplasty, is an alternative to total knee arthroplasty for patients with medial tibiofemoral and severe patellofemoral arthritis, when the lateral tibiofemoral compartment and anterior cruciate ligament are intact. This study reports the gait and subjective outcomes following medial bicompartmental arthroplasty. Methods Fifty-five subjects were measured on the instrumented treadmill at top walking speeds, using standard metrics of gait. Modular, single-stage, medial bicompartmental arthroplasty subjects (n = 16) were compared to age, body mass index, height- and sex-matched healthy (n = 19) and total knee arthroplasty (n = 20) subjects. Total knee arthroplasty subjects with pre-operative evidence of tricompartmental osteoarthritis or anterior cruciate ligament dysfunction were excluded. The vertical component of ground reaction force and temporospatial measurements were compared using Kruskal–Wallis, then Mann–Whitney test with Bonferroni correction (α = 0.05). Oxford Knee and EuroQoL EQ-5D scores were compared. Results Objectively, the medial bicompartmental arthroplasty top walking speed of 6.7 ± 0.8 km/h was 0.5 km/h (7%) slower than that of healthy controls (p = 0.2), but 1.3 km/h (24%) faster than that of total knee arthroplasty subjects (5.4 ± 0.6 km/h, p < 0.001). Medial bicompartmental arthroplasty recorded more normal maximum weight acceptance (p < 0.001) and mid-stance forces (p = 0.03) than total knee arthroplasty subjects, with 11 cm (15%) longer steps (p < 0.001) and 21 cm (14%) longer strides (p = 0.006). Subjectively, medial bicompartmental arthroplasty subjects reported Oxford Knee Scores of median 41 (interquartile range 38.8–45.5) compared to total knee arthroplasty Oxford Knee Scores of 38 (interquartile range 30.5–41, p < 0.02). Medial bicompartmental arthroplasty subjects reported EQ-5D median 0.88 (interquartile range 0.84–0.94) compared to total knee arthroplasty median 0.81 (interquartile range 0.73–0.89, p < 0.02.) Conclusion This study finds that, in the treatment of medial tibiofemoral osteoarthritis with severe patellofemoral arthritis, medial bicompartmental arthroplasty results in nearer-normal gait and improved patient-reported outcomes compared to total knee arthroplasty. Level of evidence III.

  • The compartmental approach to revision of partial knee arthroplasty results in nearer-normal gait and improved patient reported outcomes compared to total knee arthroplasty
    Amy J. Garner, Oliver W. Dandridge, Richard J. van Arkel, and Justin P. Cobb

    Springer Science and Business Media LLC
    Abstract Purpose This study investigated the gait and patient reported outcome measures of subjects converted from a partial knee arthroplasty to combined partial knee arthroplasty, using a compartmental approach. Healthy subjects and primary total knee arthroplasty patients were used as control groups. Methods Twenty-three patients converted from partial to combined partial knee arthroplasty were measured on the instrumented treadmill at top walking speeds, using standard gait metrics. Data were compared to healthy controls (n = 22) and primary posterior cruciate-retaining total knee arthroplasty subjects (n = 23) where surgery were performed for one or two-compartment osteoarthritis. Groups were matched for age, sex and body mass index. At the time of gait analysis, combined partial knee arthroplasty subjects were median 17 months post-revision surgery (range 4–81 months) while the total knee arthroplasty group was median 16 months post-surgery (range 6–150 months). Oxford Knee Scores and EuroQol-5D 5L scores were recorded at the time of treadmill assessment, and results analysed by question and domain. Results Subjects revised from partial to combined partial knee arthroplasty walked 16% faster than total knee arthroplasty (mean top walking speed 6.4 ± 0.8 km/h, vs. 5.5 ± 0.7 km/h p = 0.003), demonstrating nearer-normal weight-acceptance rate (p < 0.001), maximum weight-acceptance force (p < 0.006), mid-stance force (p < 0.03), contact time (p < 0.02), double support time (p < 0.009), step length (p = 0.003) and stride length (p = 0.051) compared to primary total knee arthroplasty. Combined partial knee arthroplasty subjects had a median Oxford Knee Score of 43 (interquartile range 39–47) vs. 38 (interquartile range 32–41, p < 0.02) and reported a median EQ-5D 0.94 (interquartile range 0.87–1.0) vs. 0.84 (interquartile range 0.80–0.89, p = 0.006). Conclusion This study finds that a compartmental approach to native compartment degeneration following partial knee arthroplasty results in nearer-normal gait and improved patient satisfaction compared to total knee arthroplasty. Level of evidence III.

  • The risk of tibial eminence avulsion fracture with bi-unicondylar knee arthroplasty A FINITE ELEMENT ANALYSIS
    Jennifer C. Stoddart, Amy Garner, Mahmut Tuncer, Justin P. Cobb, and Richard J. van Arkel

    British Editorial Society of Bone & Joint Surgery
    Aims The aim of this study was to determine the risk of tibial eminence avulsion intraoperatively for bi-unicondylar knee arthroplasty (Bi-UKA), with consideration of the effect of implant positioning, overstuffing, and sex, compared to the risk for isolated medial unicondylar knee arthroplasty (UKA-M) and bicruciate-retaining total knee arthroplasty (BCR-TKA). Methods Two experimentally validated finite element models of tibia were implanted with UKA-M, Bi-UKA, and BCR-TKA. Intraoperative loads were applied through the condyles, anterior cruciate ligament (ACL), medial collateral ligament (MCL), and lateral collateral ligament (LCL), and the risk of fracture (ROF) was evaluated in the spine as the ratio of the 95th percentile maximum principal elastic strains over the tensile yield strain of proximal tibial bone. Results Peak tensile strains occurred on the anterior portion of the medial sagittal cut in all simulations. Lateral translation of the medial implant in Bi-UKA had the largest increase in ROF of any of the implant positions (43%). Overstuffing the joint by 2 mm had a much larger effect, resulting in a six-fold increase in ROF. Bi-UKA had ~10% increased ROF compared to UKA-M for both the male and female models, although the smaller, less dense female model had a 1.4 times greater ROF compared to the male model. Removal of anterior bone akin to BCR-TKA doubled ROF compared to Bi-UKA. Conclusion Tibial eminence avulsion fracture has a similar risk associated with Bi-UKA to UKA-M. The risk is higher for smaller and less dense tibiae. To minimize risk, it is most important to avoid overstuffing the joint, followed by correctly positioning the medial implant, taking care not to narrow the bone island anteriorly. Cite this article: Bone Joint Res 2022;11(8):575–584.

  • The metabolic equivalent of task score
    Thomas C. Edwards, Brogan Guest, Amy Garner, Kartik Logishetty, Alexander D. Liddle, and Justin P. Cobb

    British Editorial Society of Bone & Joint Surgery
    Aims This study investigates the use of the metabolic equivalent of task (MET) score in a young hip arthroplasty population, and its ability to capture additional benefit beyond the ceiling effect of conventional patient-reported outcome measures. Methods From our electronic database of 751 hip arthroplasty procedures, 221 patients were included. Patients were excluded if they had revision surgery, an alternative hip procedure, or incomplete data either preoperatively or at one-year follow-up. Included patients had a mean age of 59.4 years (SD 11.3) and 54.3% were male, incorporating 117 primary total hip and 104 hip resurfacing arthroplasty operations. Oxford Hip Score (OHS), EuroQol five-dimension questionnaire (EQ-5D), and the MET were recorded preoperatively and at one-year follow-up. The distribution was examined reporting the presence of ceiling and floor effects. Validity was assessed correlating the MET with the other scores using Spearman’s rank correlation coefficient and determining responsiveness. A subgroup of 92 patients scoring 48/48 on the OHS were analyzed by age, sex, BMI, and preoperative MET using the other metrics to determine if differences could be established despite scoring identically on the OHS. Results Postoperatively the OHS and EQ-5D demonstrate considerable negatively skewed distributions with ceiling effects of 41.6% and 53.8%, respectively. The MET was normally distributed postoperatively with no relevant ceiling effect. Weak-to-moderate significant correlations were found between the MET and the other two metrics. In the 48/48 subgroup, no differences were found comparing groups with the EQ-5D, however significantly higher mean MET scores were demonstrated for patients aged < 60 years (12.7 (SD 4.7) vs 10.6 (SD 2.4), p = 0.008), male patients (12.5 (SD 4.5) vs 10.8 (SD 2.8), p = 0.024), and those with preoperative MET scores > 6 (12.6 (SD 4.2) vs 11.0 (SD 3.3), p = 0.040). Conclusion The MET is normally distributed in patients following hip arthroplasty, recording levels of activity which are undetectable using the OHS. Cite this article: Bone Joint Res 2022;11(5):317–326.

  • Variation in the patellar tendon moment arm identified with an improved measurement framework
    Oliver Dandridge, Amy Garner, Andrew A. Amis, Justin P. Cobb, and Richard J. Arkel

    Wiley
    The mechanical advantage of the knee extensor mechanism depends heavily on the patellar tendon moment arm (PTMA). Understanding which factors contribute to its variation may help improve functional outcomes following arthroplasty. This study optimized PTMA measurement, allowing us to quantify the contribution of different variables. The PTMA was calculated about the instantaneous helical axis of tibiofemoral rotation from optical tracked kinematics. A fabricated knee model facilitated calculation optimization, comparing four data smoothing techniques (raw, Butterworth filtering, generalized cross‐validated cubic spline‐interpolation and combined filtering/interpolation). The PTMA was then measured for 24 fresh‐frozen cadaveric knees, under physiologically based loading and extension rates. Combined filtering/interpolation enabled sub‐mm PTMA calculation accuracy throughout the range of motion (root‐mean‐squared error 0.2 mm, max error 0.4 mm), whereas large errors were measured for raw, filtered‐only and interpolated‐only techniques at terminal flexion/extension. Before scaling, the mean PTMA was 46 mm; PTMA magnitude was consistently larger in males (mean differences: 5 to 10 mm, p < .05) and was strongly related to knee size: larger knees have a larger PTMA. However, while scaling eliminated sex differences in PTMA magnitude, the peak PTMA occurred closer to terminal extension in females (female 15°, male 29°, p = .01). Knee size accounted for two‐thirds of the variation in PTMA magnitude, but not the flexion angle where peak PTMA occurred. This substantial variation in angle of peak PTMA has implications for the design of musculoskeletal models and morphotype‐specific arthroplasty. The developed calculation framework is applicable both in vivo and vitro for accurate PTMA measurement.

  • Validity of repeated-measures analyses of in vitro arthroplasty kinematics and kinetics
    Oliver Dandridge, Amy Garner, Jonathan R.T. Jeffers, Andrew A. Amis, Justin P. Cobb, and Richard J. van Arkel

    Elsevier BV

  • Bi-unicondylar arthroplasty
    Amy J. Garner, Oliver W. Dandridge, Andrew A. Amis, Justin P. Cobb, and Richard J. van Arkel

    British Editorial Society of Bone & Joint Surgery
    Aims Bi-unicondylar arthroplasty (Bi-UKA) is a bone and anterior cruciate ligament (ACL)-preserving alternative to total knee arthroplasty (TKA) when the patellofemoral joint is preserved. The aim of this study is to investigate the clinical outcomes and biomechanics of Bi-UKA. Methods Bi-UKA subjects (n = 22) were measured on an instrumented treadmill, using standard gait metrics, at top walking speeds. Age-, sex-, and BMI-matched healthy (n = 24) and primary TKA (n = 22) subjects formed control groups. TKA subjects with preoperative patellofemoral or tricompartmental arthritis or ACL dysfunction were excluded. The Oxford Knee Score (OKS) and EuroQol five-dimension questionnaire (EQ-5D) were compared. Bi-UKA, then TKA, were performed on eight fresh frozen cadaveric knees, to investigate knee extensor efficiency under controlled laboratory conditions, using a repeated measures study design. Results Bi-UKA walked 20% faster than TKA (Bi-UKA mean top walking speed 6.7 km/h (SD 0.9),TKA 5.6 km/h (SD 0.7), p &lt; 0.001), exhibiting nearer-normal vertical ground reaction forces in maximum weight acceptance and mid-stance, with longer step and stride lengths compared to TKA (p &lt; 0.048). Bi-UKA subjects reported higher OKS (p = 0.004) and EQ-5D (p &lt; 0.001). In vitro, Bi-UKA generated the same extensor moment as native knees at low flexion angles, while reduced extensor moment was measured following TKA (p &lt; 0.003). Conversely, at higher flexion angles, the extensor moment of TKA was normal. Over the full range, the extensor mechanism was more efficient following Bi-UKA than TKA (p &lt; 0.028). Conclusion Bi-UKA had more normal gait characteristics and improved patient-reported outcomes, compared to matched TKA subjects. This can, in part, be explained by differences in extensor efficiency. Cite this article: Bone Joint Res 2021;10(11):723–733.

  • Partial and Combined Partial Knee Arthroplasty: Greater Anterior-Posterior Stability Than Posterior Cruciate–Retaining Total Knee Arthroplasty
    Amy J. Garner, Oliver W. Dandridge, Andrew A. Amis, Justin P. Cobb, and Richard J. van Arkel

    Elsevier BV

  • The revision partial knee classification system: understanding the causative pathology and magnitude of further surgery following partial knee arthroplasty
    Amy J. Garner, Thomas C. Edwards, Alexander D. Liddle, Gareth G. Jones, and Justin P. Cobb

    British Editorial Society of Bone & Joint Surgery
    Aims Joint registries classify all further arthroplasty procedures to a knee with an existing partial arthroplasty as revision surgery, regardless of the actual procedure performed. Relatively minor procedures, including bearing exchanges, are classified in the same way as major operations requiring augments and stems. A new classification system is proposed to acknowledge and describe the detail of these procedures, which has implications for risk, recovery, and health economics. Methods Classification categories were proposed by a surgical consensus group, then ranked by patients, according to perceived invasiveness and implications for recovery. In round one, 26 revision cases were classified by the consensus group. Results were tested for inter-rater reliability. In round two, four additional cases were added for clarity. Round three repeated the survey one month later, subject to inter- and intrarater reliability testing. In round four, five additional expert partial knee arthroplasty surgeons were asked to classify the 30 cases according to the proposed revision partial knee classification (RPKC) system. Results Four classes were proposed: PR1, where no bone-implant interfaces are affected; PR2, where surgery does not include conversion to total knee arthroplasty, for example, a second partial arthroplasty to a native compartment; PR3, when a standard primary total knee prosthesis is used; and PR4 when revision components are necessary. Round one resulted in 92% inter-rater agreement (Kendall’s W 0.97; p &lt; 0.005), rising to 93% in round two (Kendall’s W 0.98; p &lt; 0.001). Round three demonstrated 97% agreement (Kendall’s W 0.98; p &lt; 0.001), with high intra-rater reliability (interclass correlation coefficient (ICC) 0.99; 95% confidence interval 0.98 to 0.99). Round four resulted in 80% agreement (Kendall’s W 0.92; p &lt; 0.001). Conclusion The RPKC system accounts for all procedures which may be appropriate following partial knee arthroplasty. It has been shown to be reliable, repeatable and pragmatic. The implications for patient care and health economics are discussed. Cite this article: Bone Jt Open 2021;2(8):638–645.

  • The compartmental distribution of knee osteoarthritis – a systematic review and meta-analysis
    J.C. Stoddart, O. Dandridge, A. Garner, J. Cobb, and R.J. van Arkel

    Elsevier BV

  • The extensor efficiency of unicompartmental, bicompartmental, and total knee arthroplasty
    Amy Garner, Oliver Dandridge, Andrew A. Amis, Justin P. Cobb, and Richard J. van Arkel

    British Editorial Society of Bone & Joint Surgery
    Aims Unicompartmental knee arthroplasty (UKA) and bicompartmental knee arthroplasty (BCA) have been associated with improved functional outcomes compared to total knee arthroplasty (TKA) in suitable patients, although the reason is poorly understood. The aim of this study was to measure how the different arthroplasties affect knee extensor function. Methods Extensor function was measured for 16 cadaveric knees and then retested following the different arthroplasties. Eight knees underwent medial UKA then BCA, then posterior-cruciate retaining TKA, and eight underwent the lateral equivalents then TKA. Extensor efficiency was calculated for ranges of knee flexion associated with common activities of daily living. Data were analyzed with repeated measures analysis of variance (α = 0.05). Results Compared to native, there were no reductions in either extension moment or efficiency following UKA. Conversion to BCA resulted in a small decrease in extension moment between 70° and 90° flexion (p &lt; 0.05), but when examined in the context of daily activity ranges of flexion, extensor efficiency was largely unaffected. Following TKA, large decreases in extension moment were measured at low knee flexion angles (p &lt; 0.05), resulting in 12% to 43% reductions in extensor efficiency for the daily activity ranges. Conclusion This cadaveric study found that TKA resulted in inferior extensor function compared to UKA and BCA. This may, in part, help explain the reported differences in function and satisfaction differences between partial and total knee arthroplasty. Cite this article: Bone Joint Res 2021;10(1):1–9.

  • Combined partial knee arthroplasty
    Amy Garner and Justin Cobb

    Springer International Publishing
    AbstractArthrosis commonly affects a single compartment of the knee, but may present with two or even three compartments affected. Wear to the medial tibiofemoral compartment is ten times more common than that in the lateral tibiofemoral compartment; primary patellofemoral joint (PFJ) arthrosis is least common [1, 2]. Bicompartmental disease is present in 59% of those with gonarthrosis [3]. In one study, 40% of patients over 50 years old with knee pain had radiographic evidence of combined medial compartment and PFJ wear, 24% had isolated PFJ arthrosis, whilst only 4% had isolated tibiofemoral arthrosis [4]. Degeneration of all three compartments simultaneously is rare [2]. Consequently, removal of healthy tissue in total knee arthroplasty (TKA) is common. The anterior cruciate ligament (ACL) is present in 78% of cases of patients undergoing primary knee replacement [5]. The fundamental role of the ACL in knee stability and functional gait is well described [6]; however, regardless of its functional integrity, it is resected in almost all TKAs.

  • Classification of combined partial knee arthroplasty
    A. Garner, R. J. van Arkel, and J. Cobb

    British Editorial Society of Bone & Joint Surgery
    Aims There has been a recent resurgence in interest in combined partial knee arthroplasty (PKA) as an alternative to total knee arthroplasty (TKA). The varied terminology used to describe these procedures leads to confusion and ambiguity in communication between surgeons, allied health professionals, and patients. A standardized classification system is required for patient safety, accurate clinical record-keeping, clear communication, correct coding for appropriate remuneration, and joint registry data collection. Materials and Methods An advanced PubMed search was conducted, using medical subject headings (MeSH) to identify terms and abbreviations used to describe knee arthroplasty procedures. The search related to TKA, unicompartmental (UKA), patellofemoral (PFA), and combined PKA procedures. Surveys were conducted of orthopaedic surgeons, trainees, and biomechanical engineers, who were asked which of the descriptive terms and abbreviations identified from the literature search they found most intuitive and appropriate to describe each procedure. The results were used to determine a popular consensus. Results Survey participants preferred “bi-unicondylar arthroplasty” (Bi-UKA) to describe ipsilateral medial and lateral unicompartmental arthroplasty; “medial bi-compartmental arthroplasty” (BCA-M) to describe ipsilateral medial unicompartmental arthroplasty with patellofemoral arthroplasty; “lateral bi-compartmental arthroplasty” (BCA-L) to describe ipsilateral lateral unicompartmental arthroplasty with patellofemoral arthroplasty; and tri-compartmental arthroplasty (TCA) to describe ipsilateral patellofemoral and medial and lateral unicompartmental arthroplasties. “Combined partial knee arthroplasty” (CPKA) was the favoured umbrella term. Conclusion We recommend bi-unicondylar arthroplasty (Bi-UKA), medial bicompartmental arthroplasty (BCA-M), lateral bicompartmental arthroplasty (BCA-L), and tricompartmental arthroplasty (TCA) as the preferred terms to classify CPKA procedures. Cite this article: Bone Joint J 2019;101-B:922–928.

  • Morel-Lavallée lesions of the knee: A closed degloving injury: A report of two cases
    Amy Garner, David Beard, Simon Ostlere, Andrew Price, and Rajesh Rout

    Wiley
    The Morel-Lavallée lesion (MLL) was first described by the French physician, Maurice Morel-Lavallée, in 1853 as a closed degloving injury in the pelvis. A shearing force results in skin and subcutaneous tissue being separated from the underlying fascia. Disruption of bridging blood and lymphatic vessels leads to a collection of fluid in the plane created as a result of the injury. In the normal tissue, vessels penetrating the fascia perfuse the skin. However, in a closed degloving injury, these vessels are disrupted. In this scenario, the skin can draw supply via the dermal and subcutaneous vascular plexus, but the risk of ischaemic injury is increased. MLLs around the greater trochanter, flanks and buttocks are well described in the literature. However, a series of MLLs of the knee, prepatellar closed degloving injuries, were only formally described as recently as 2007. Here, we describe two cases of the MLL presenting to our specialist orthopaedic hospital over the past two years. Through these cases, we highlight possible mechanisms of injury resulting in an MLL, its pathology and its natural progression. We describe options for clinicians in the management of an MLL of the knee. A 30-year-old man sustained an injury to his right knee while playing lacrosse where his knee collided with the artificial turf playing surface. Anterior swelling was immediate and the knee was diffusely tender anteriorly. His range of motion was 5–90 degrees of flexion during the first 24 h and reduced to 5–60 degrees by day 2. The medial and lateral collateral ligaments appeared intact; it was not possible to assess the cruciate ligaments due to pain. Weight bearing, though possible, was painful. Five days after the injury, the knee remained swollen and tender. A magnetic resonance imaging (MRI) scan, performed on the same day, revealed a prepatellar collection extending beyond the prepatellar bursa. There was a small joint effusion but no other abnormality. After 7 days, the pain had improved and full, pain-free weight bearing was possible by day 14. The patient returned to training after 6 weeks. The swelling remained until 8 weeks post-injury, at which point full range of movement was possible. Repeat examination confirmed full resolution of the clinical injury by the eighth week post-injury. One year later, the same mechanism led to recurrence. The knee exhibited a larger prepatellar collection than the first incident. There was also marked ecchymosis in the region of the medial collateral ligament (MCL) seen in the clinical photos (Fig. 1). However, there was no tenderness over MCL and stress testing demonstrated neither pain nor laxity. The symptoms and signs resolved over the period of 1 month. A 31-year-old motorcyclist sustained a right knee injury during a 20-mph road traffic accident. He had no history of knee injury, pain or swelling. The patient’s knee was the first point of impact, colliding directly with a stationary car. Anterior prepatellar swelling was immediate. Examination on the day of injury revealed stable collateral ligaments. Pain prevented examination of the cruciate ligaments. Antero-medial soft tissue swelling was visible and could also be seen on X-ray (Fig. 2); no concurrent bony injuries were present. The patient was unable to weight-bear for 24 h due to pain. Anterior prepatella cutaneous sensation to light-touch and temperature was markedly reduced. Antero-medial knee pain and swelling persisted for 4 weeks, at which time an MRI scan was performed demonstrating a 10 × 7.5 × 2-cm loculated fluid collection over the anterior aspect of the knee (Fig. 2). Swelling, reduced sensation and pain persisted despite physiotherapy, strapping, repeated application of ice and patientadministered cryotherapy. Five months post-injury, an arthroscopy was performed. A small medial meniscal tear was debrided, but no other significant pathology was seen and the procedure did not resolve his symptoms. Seven months later, an injection of local Fig. 1. Clinical photograph: day 2 post-recurrent injury – prepatellar swelling and marked bruising on the medial side of the right knee.

  • Screening tools in the diagnosis of acute compartment syndrome
    Amy J. Garner and Ashok Handa

    SAGE Publications
    Acute compartment syndrome (ACS) is a surgical emergency requiring urgent fasciotomy to save the limb. However, time is of the essence and diagnostic uncertainty can lead to unnecessary surgery. Measurement of intracompartmental pressure (ICP) to aid decision making is becoming commonplace, particularly in unconscious or confused patients. However, inaccurate readings can result from misplacement of the probe, subjecting patients to a needless fasciotomy in the event of an overreading. Similarly, underestimated readings create a false sense of security. Screening tools, criteria-led systems of clinical decision making, are used by some to assist in diagnosis and management planning, but do they work? Here, we review current diagnostic strategies and question whether screening tools can make rapid diagnosis more accurate. Furthermore, in the absence of a standardized tool, we analyze the practice of a sample of vascular surgeons with the aim of moving toward a management consensus useful to junior doctors.