Dr.S.Imam Pasha
@sucp.ac.in
Associate Professor/Pharmaceutical Quality Assurance
Sultan -ul-Uloom College of Pharmacy
EDUCATION
PhD(Pharmaceutical Analysis & Quality Assurance) from Jawaharlal Nehru Technological University, Hyderabad.
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M. Pharmacy(Pharmaceutical Quality Assurance) from Jawaharlal Nehru Technological University, Hyderabad ,First Class with Distinction (87%).
B. Pharmacy from Jawaharlal Nehru Technological University, Hyderabad,First Division (75.2%)
Intermediate-MPC(10+2),Board of Intermediate Education, Hyderabad,First Division (90%)
SSC(10th ),Board of Secondary Education, Hyderabad, Telangana State, India,First Division (81%)
RESEARCH, TEACHING, or OTHER INTERESTS
Pharmacy, Analytical Chemistry, Pharmacology (medical), Chemistry
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Imam Pasha S, Murali Balaram Varanasi, and Ibrahim Mohammed
Elsevier BV
Imam Pasha. S, Murali Balaram.Varanasi, and Ibrahim Mohammed
Oriental Scientific Publishing Company
Stability representing Ultra Performance LC method was developed for Assay of multi drug Combination of Rilpivirine, Emtricitabine and Tenofovir alafenamide in bulk active pharmaceutical ingredients & its tablet formulation, Validation was performed for all parameters .Retention times of Reference Standard Emtricitabine, Tenofovir Alafenamide and Rilpivirine was found to be 0.965, 1.528, 2.186 respectively, with the flow rate of 0.3 mille liters per minute by Injecting Volume of 2 micro liters by maintaining Run time of 3 minutes. Developed method was subjected to forced degradation studies under specified conditions, which meets the required criteria. Degradation product at 1.975 Rt was collected under various stress condition, cleavage of imidazole ring of tenafovir alafenamide confirmed with Proton NMR, ESI –MASS in + MODE.
Ghazala Yasmeen, Mohd Ibrahim, V Balram, S Pasha, Sadaf Rahman, and Mohsina Abid
Oriental Scientific Publishing Company
Miniaturization in High Throughput Screening (HTS) is perceived as essential by pharmaceutical screening laboratories to accommodate the enormous increase in compounds and targets over the past few years. The two primary goals are to increase throughput while decreasing costs. The ability to perform primary screening assays in high-density micro-well plates at volumes of 1–2μl will accelerate the early stages of drug discovery. Ultra-HTS (uHTS) assays require an accurate and reliable means of fluid handling in the submicroliter volume range. This relates to the design of instrumentation for dispensing fluids, as well as assay plates. Fluid handling has been a major obstacle to the full implementation of miniaturized assays. This report focuses on current approaches to submicroliter fluid handling in high-density multi-well plates.
Nalluri Jyothi and Syed Pasha
Oriental Scientific Publishing Company
An isocratic, reversed phase-liquid chromatographic method was developed for quantitative determination of N-acetylcysteine and L-Arginine in combined dosage form. A Waters Xterra Rp8, (150*4.6*5µm) column with a mobile phase containing a Phosphate Buffer (pH 4.5) and Methanol (90: 10 v/v) was used. The flow rate was maintained at 0.8 ml/min, column temperature at 30°C and effluents were monitored at 248 nm. The retention times of N-acetylcysteine and L-Arginine were found to be 2.697 min and 3.156 min, respectively. The correlation co-efficient for N-acetylcysteine and L-Arginine was found to be 0.99 and 0.99, respectively. The proposed method was validated with respect to linearity, accuracy, precision, specificity, and robustness. Recovery of N-acetylcysteine and L-Arginine in formulations was found to be in the range of 97-103% and 97-103% respectively confirms the non-interferences of the excipients in formulation. Due to its simplicity, rapidness and high precision, this method can be successfully applied for estimation of N-acetylcysteine and L-Arginine in combined pharmaceutical dosage forms.
S.Imam pasha, Shravan kumar A, K. Sravanthi, G. Srinika, and V. Nikhila
Oriental Scientific Publishing Company
A simple, sensitive and economical spectrophotometric method was developed for the determination of cefixime trihydrate in pharmaceutical formulations. This method is based on the formation of pink colored chromogen complex by the reaction of drug with ferric chloride and 2, 2 bipyridyl, which absorbs maximally at 520 nm. Beer’s law is obeyed at a concentration range of 110 mcg/ml for method. This method has been successfully applied for the assay of the drug in pharmaceutical formulations.
RECENT SCHOLAR PUBLICATIONS
MOST CITED SCHOLAR PUBLICATIONS
Publications
1. Imam Pasha.S, Ibrahim Mohammed , Murali Balaram Varanasi, Bio analysis of Monomethyl Fumarate in human plasma by a sensitive and rapid LC-MS/MS method and its pharmacokinetic application; Journal of Pharmaceutical and Biomedical Analysis(JPBA); ISSN Number :07317085;e -ISSN Number :1873264X; Source: WoS & Scopus; Impact Factor: 3.2; Volume:146 , Pages:109–116
2. Imam Pasha.S, Ibrahim Mohammed , Murali Balaram Varanasi; Stability indicating RP UPLC-PDA method development, validation of multi drug combination of Emtricitabine, Tenofovir alafenamide and Rilpivirine in bulk drug and its tablet formulation; Oriental Journal of Chemistry; ISSN-Number:0970020X; Scientific Publishers; Volume:33(2);Page No’s: 925 -929
3. Mohammad Younus; Imam M. Siddiq;A.P; Lakshmi; RP-HPLC method development and validation for estimatation of isradipine in tablet dosage form; Asian Journal of Pharmaceutical and Clinical Research; ISSN: 2455-3891 Print ISSN: 0974-2441);Volume: 6(1);2013,Page No’s :140-142.
4. Azmath unissa, Anupama Koneru, M.mushraff Ali Khan, Murali Balaram Varanasi and Imam Pasha Syed, Development of Stability Indicating, Validated Liquid Chromatographic Method for Estimation of Sarecycline in its Formulations; Oriental Journal of Chemistry; ISSN Number:0970020X; Scientific Publishers; Volume:35(6);Page No’s: 1805-1812
5. Imam Pasha.S, Ibrahim Mohammed , Murali Balaram Varanasi;Analytical method validation for the identification and determination of limit of Ur
RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)
1. Indian Patent entitled “Synthesis and characterization of Vanadium complexes with Quadridentate Schiff bases”; Date of Filing: 28/06/2022; Publication Date :08/07/2022