Salvatore Calogero Gaglio

@ddsp.univr.it

Department of Biotechnology
University of Verona

RESEARCH, TEACHING, or OTHER INTERESTS

Colloid and Surface Chemistry, Biomaterials, Biotechnology, Multidisciplinary
14

Scopus Publications

173

Scholar Citations

9

Scholar h-index

9

Scholar i10-index

Scopus Publications

  • Extracellular vesicles from long COVID patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation
    Luca Dalle Carbonare, Arianna Minoia, Sharazed Zouari, Michele Braggio, Mattia Cominacini, et al.
    Cell Communication and Signaling, 2025
    Background Subjects with Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), experience a wide range of symptoms, including fatigue and respiratory disturbances, affecting their quality of life. Despite the increasing prevalence of Long COVID, the underlying pathogenic mechanisms remain poorly understood. Extracellular vesicles (EVs) are known to be involved in various processes, such as tissue repair and the transmission of viral particles. However, the specific characteristics and functional roles of EVs derived- from patients with Long COVID (LC-EVs) are poorly characterized. Methods To uncover systemic mechanisms underlying Long COVID, we performed a comprehensive characterization of patient-derived extracellular vesicles (EVs) via Nanoparticle Tracking analysis (NTA), Atomic Force Microscopy (AFM), Transmission Electron Microscope (TEM) and flow cytometry. These EVs were applied to lung cells, Mesenchymal Stem Cell (MSCs), Human Umbilical Vein Endothelial Cells (HUVECs) and Aortic Smooth Muscle Cells (ASMCs), revealing stress responses through SESN1, SESN2, and p53 activation. We further assessed mitochondrial respiration to evaluate metabolic dysfunction, and conducted targeted transfection experiments to dissect the molecular pathways involved, shedding light on EV-driven cellular reprogramming. Results Thus, we observed that Long COVID (LC) patients experienced breathlessness and leg discomfort during exertion. Our data highlighted that LC-EVs induce aberrant RUNX2 expression and activate the p53/p21 pathway in lung cells as well stress responses. Additionally, LC-EVs impair mitochondrial function and cellular adaptability under metabolic stress, reducing maximal respiration and ATP production at high cell densities. Protein interaction analysis showed RUNX2 involvement in key biological processes and post-transcriptional regulation by hsa-miR-204-5p was identified. Finally, LC-EVs also activated stress pathways and increased RUNX2, SESN, p53, and p21 levels in endothelial cells, aortic smooth muscle cells, and mesenchymal stem cells. Conclusions In conclusions, these findings provide new insights into the role of extracellular vesicles in Long COVID, revealing their involvement in cellular stress and impaired mitochondrial function.
  • Magnetic hyperthermia drastically enhances killing of Mycobacterium tuberculosis by bacteriocin AS-48 grafted on biomimetic nanoparticles
    Monica Jimenez-Carretero, Ana Belén Gómez, Marina Lázaro, Ana Cristina Millán-Placer, Salvatore C. Gaglio, et al.
    International Journal of Biological Macromolecules, 2025
  • Evaluation of Biocontrol Measures to Reduce Bacterial Load and Healthcare-Associated Infections
    Anna Vareschi, Salvatore Calogero Gaglio, Kevin Dervishi, Arianna Minoia, Giorgia Zanella, et al.
    Microorganisms, 2025
    Hospital-acquired infections (HAIs) remain a major clinical and economic burden, with pathogens such as Escherichia coli contributing to high rates of morbidity and mortality. Traditional manual disinfection methods are often insufficient, particularly in high-risk hospital environments. In this study, we investigated innovative strategies to enhance surface decontamination and reduce infection risk. First, we assessed the efficacy of the SMEG BPW1260 bedpan washer-disinfector, a thermal disinfection system for human waste containers. Our results demonstrated a reduction in Clostridium difficile and Escherichia coli contamination by >99.9% (>3 log reduction), as measured by colony-forming units (CFU) before and after treatment. Molecular techniques, including spectrophotometry, cell counting, and quantitative PCR (qPCR) for DNA quantification, confirmed reduction in bacterial contamination. Specifically, Clostridium difficile showed a reduction of approximately 89% in both optical density (OD) and cell count (cells/mL). In the case of Escherichia coli, a reduction of around 82% in OD was observed, with an even more pronounced decrease in cell count, reaching approximately 99.3%. For both bacteria, DNA quantification by qPCR was below detectable limits. Furthermore, we optimized the energy efficiency of the disinfection cycle, achieving a 45% reduction in power consumption compared to standard protocols without compromising antimicrobial efficacy. Secondly, we developed a sustainable cleaning solution based on methyl ester sulfonate surfactants derived from waste cooking oil. The detergent’s antibacterial activity was tested on contaminated surfaces and further enhanced through the incorporation of nanoassemblies composed of silver, electrostatically bound either to biomimetic magnetic nanoparticles or to conventional magnetic nanoparticles. Washing with the detergent alone effectively eliminated detectable contamination, while the addition of nanoparticles inhibited bacterial regrowth. Antimicrobial testing against E. coli revealed that the nanoparticle-enriched formulations reduced the average MIC values by approximately 50%, with MIC50 values around 0.03–0.06 mg/mL and MIC90 values between 0.06 and 0.12 mg/mL, indicating improved inhibitory efficacy. Finally, recognizing the infection risks associated with intra-hospital transport, we tested the SAFE-HUG Wheelchair Cover, a disposable non-woven barrier designed to reduce patient exposure to contaminated wheelchair surfaces. Use of the cover resulted in a 3.3 log reduction in surface contamination, based on viable cell counts. Optical density and bacterial DNA were undetectable in all covered samples at both 1 and 24 h, confirming the strong barrier effect. Together, these approaches—thermal no-touch disinfection, eco-friendly detergent boosted with nanoparticles, and protective transport barriers—respond to the urgent need for effective, sustainable infection control methods in healthcare settings. Our findings demonstrate the potential of these systems to counteract microbial contamination while minimizing environmental impact, offering promising solutions for the future of infection prevention in healthcare settings.
  • Enhanced Stability and Photochemical Activity of Photosystem I from the Green Alga Chlamydomonas reinhardtii Upon Encapsulation in Organic Matrixes
    Salvatore C. Gaglio, Giorgia Zanella, Stefano Cazzaniga, Nico Olivieri, Elia Battagini, et al.
    ACS Sustainable Chemistry and Engineering, 2025
  • Efficiency of Chitosan Nanocarriers in Vaccinology for Mucosal Immunization
    Salvatore Calogero Gaglio, Massimiliano Perduca, Donato Zipeto, Giuseppe Bardi
    Vaccines, 2023
    The mucosal barrier constitutes a huge surface area, close to 40 m2 in humans, located mostly in the respiratory, gastrointestinal and urogenital tracts and ocular cavities. It plays a crucial role in tissue interactions with the microbiome, dietary antigens and other environmental materials. Effective vaccinations to achieve highly protective mucosal immunity are evolving strategies to counteract several serious diseases including tuberculosis, diphtheria, influenzae B, severe acute respiratory syndrome, Human Papilloma Virus infection and Acquired Immune Deficiency Syndrome. Interestingly, one of the reasons behind the rapid spread of severe acute respiratory syndrome coronavirus 2 variants has been the weakness of local immunization at the level of the respiratory mucosa. Mucosal vaccines can outperform parenteral vaccination as they specifically elicit protective mucosal immune responses blocking infection and transmission. In this scenario, chitosan-based nanovaccines are promising adjuvants-carrier systems that rely on the ability of chitosan to cross tight junctions and enhance particle uptake due to chitosan-specific mucoadhesive properties. Indeed, chitosan not only improves the adhesion of antigens to the mucosa promoting their absorption but also shows intrinsic immunostimulant abilities. Furthermore, by finely tuning the colloidal properties of chitosan, it can provide sustained antigen release to strongly activate the humoral defense. In the present review, we agnostically discuss the potential reasons why chitosan-based vaccine carriers, that efficiently elicit strong immune responses in experimental setups and in some pre-clinical/clinical studies, are still poorly considered for therapeutic formulations.
  • Ln(III) Complexes Embedded in Biocompatible PLGA Nanoparticles as Potential Vis-to-NIR Optical Probes
    Fabio Piccinelli, Silvia Mizzoni, Giorgia Zanella, Salvatore Calogero Gaglio, Massimiliano Perduca, et al.
    Molecules, 2023
    In this contribution, we present the spectroscopic study of two NIR emitting hydrophobic heteroleptic (R,R)-YbL1(tta) and (R,R)-NdL1(tta) complexes (with tta = 2-thenoyltrifluoroacetonate and L1 = N,N′-bis(2-(8-hydroxyquinolinate)methylidene)-1,2-(R,R or S,S)-cyclohexanediamine), both in methanol solution and embedded in water dispersible and biocompatible poly lactic-co-glycolic acid (PLGA) nanoparticles. Thanks to their absorption properties in a wide range of wavelengths extending from the UV up to the blue and green visible regions, the emission of these complexes can be effectively sensitized using visible radiation, which is much less harmful to tissues and skin than the UV one. The encapsulation of the two Ln(III)-based complexes in PLGA allows us to preserve their nature, making them stable in water and to test their cytotoxicity on two different cell lines, with the aim of using them in the future as potential bioimaging optical probes.
  • Effects of Magnetic Nanoparticles on the Functional Activity of Human Monocytes and Dendritic Cells
    Marta Donini, Francesca Pettinella, Giorgia Zanella, Salvatore Calogero Gaglio, Carlo Laudanna, et al.
    International Journal of Molecular Sciences, 2023
    The use of nanoparticles in medicine is sometimes hampered by their potential to activate immune cells, eliciting inflammation or allergy. We investigated whether magnetic nanoparticles (MNPs) or biomimetic magnetic nanoparticles (BMNPs) affect relevant activities of human monocytes. We found that the nanoparticles neither elicited the production of pro-inflammatory mediators IL-6 and TNFα by resting monocytes (when BMNP dose < 300 μg/mL) nor enhanced their secretion induced by R848, a molecule engaging virus-recognizing receptors, or bacterial lipopolysaccharide (LPS). MNPs and BMNPs neither induced the generation of reactive oxygen species (ROS), nor affected the ROS production elicited by the NADPH oxidase activator phorbol myristate acetate (PMA) or the fungal derivative β-glucan. BMNPs, but not MNPs, caused an up-regulation of the maturation markers CD80, CD83, and CD86 in immature monocyte-derived dendritic cells (DCs), whereas both nanoparticles did not affect the LPS-induced expression of these markers. Moreover, the nanoparticles were greedily ingested by monocytes and DCs without altering their viability. Therefore, these nanoparticles are candidates for medical applications because they do not activate pro-inflammatory activities of monocytes. Furthermore, their ability to stimulate DC maturation could be used for the design of vaccines. Moreover, harmlessly engulfed nanoparticles could be vehicles to carry molecules inside the immune cells to regulate the immune response.
  • Embedding Biomimetic Magnetic Nanoparticles Coupled with Peptide AS-48 into PLGA to Treat Intracellular Pathogens
    Salvatore Calogero Gaglio, Ylenia Jabalera, Manuel Montalbán-López, Ana Cristina Millán-Placer, Marina Lázaro-Callejón, et al.
    Pharmaceutics, 2022
    Among the strategies employed to overcome the development of multidrug-resistant bacteria, directed chemotherapy combined with local therapies (e.g., magnetic hyperthermia) has gained great interest. A nano-assembly coupling the antimicrobial peptide AS-48 to biomimetic magnetic nanoparticles (AS-48-BMNPs) was demonstrated to have potent bactericidal effects on both Gram-positive and Gram-negative bacteria when the antimicrobial activity of the peptide was combined with magnetic hyperthermia. Nevertheless, intracellular pathogens remain challenging due to the difficulty of the drug reaching the bacterium. Thus, improving the cellular uptake of the nanocarrier is crucial for the success of the treatment. In the present study, we demonstrate the embedding cellular uptake of the original nano-assembly into THP-1, reducing the toxicity of AS-48 toward healthy THP-1 cells. We optimized the design of PLGA[AS-48-BMNPs] in terms of size, colloidal stability, and hyperthermia activity (either magnetic or photothermal). The stability of the nano-formulation at physiological pH values was evaluated by studying the AS-48 release at this pH value. The influence of pH and hyperthermia on the AS-48 release from the nano-formulation was also studied. These results show a slower AS-48 release from PLGA[AS-48-BMNPs] compared to previous nano-formulations, which could make this new nano-formulation suitable for longer extended treatments of intracellular pathogens. PLGA[AS-48-BMNPs] are internalized in THP-1 cells where AS-48 is liberated slowly, which may be useful to treat diseases and prevent infection caused by intracellular pathogens. The treatment will be more efficient combined with hyperthermia or photothermia.
  • Near Infared Circularly Polarized Luminescence From Water Stable Organic Nanoparticles Containing a Chiral Yb(III) Complex
    Enrico Cavalli, Chiara Nardon, Oliver G. Willis, Francesco Zinna, Lorenzo Di Bari, et al.
    Chemistry A European Journal, 2022
    We report the first example of very efficient NIR Circularly Polarized Luminescence (CPL) (around 970 nm) in water, obtained thanks to the combined use of a chiral Yb complex and of poly lactic‐co‐glycolic acid (PLGA) nanoparticles. [YbL(tta)2]CH3COO (L=N, N’‐bis(2‐pyridylmethylidene)‐1,2‐(R,R+S,S) cyclohexanediamine and tta=2‐thenoyltrifluoroacetonate) shows good CPL in organic solvents, because the tta ligands efficiently sensitize Yb NIR luminescence and the readily prepared chiral ligand L endows the complex with the necessary dissymmetry. PLGA nanoparticles incorporate the complex and protect the metal ion from the intrusion of solvent molecules, while ensuring biocompatibility, water solubility and stability to the complex. Hydrophilic NIR‐CPL optical probes can find applications in the field of NIR‐CPL bio‐assays.
  • Fisetin: An Integrated Approach to Identify a Strategy Promoting Osteogenesis
    Luca Dalle Carbonare, Jessica Bertacco, Salvatore Calogero Gaglio, Arianna Minoia, Mattia Cominacini, et al.
    Frontiers in Pharmacology, 2022
    Flavonoids may modulate the bone formation process. Among flavonoids, fisetin is known to counteract tumor growth, osteoarthritis, and rheumatoid arthritis. In addition, fisetin prevents inflammation-induced bone loss. In order to evaluate its favorable use in osteogenesis, we assayed fisetin supplementation in both in vitro and in vivo models and gathered information on nanoparticle-mediated delivery of fisetin in vitro and in a microfluidic system. Real-time RT-PCR, Western blotting, and nanoparticle synthesis were performed to evaluate the effects of fisetin in vitro, in the zebrafish model, and in ex vivo samples. Our results demonstrated that fisetin at 2.5 µM concentration promotes bone formation in vitro and mineralization in the zebrafish model. In addition, we found that fisetin stimulates osteoblast maturation in cell cultures obtained from cleidocranial dysplasia patients. Remarkably, PLGA nanoparticles increased fisetin stability and, consequently, its stimulating effects on RUNX2 and its downstream gene SP7 expression. Therefore, our findings demonstrated the positive effects of fisetin on osteogenesis and suggest that patients affected by skeletal diseases, both of genetic and metabolic origins, may actually benefit from fisetin supplementation.
  • Enhanced cytotoxic effect of tat–plga‐embedded doxo carried by biomimetic magnetic nanoparticles upon combination with magnetic hyperthermia and photothermia
    Ylenia Jabalera, Alberto Sola-Leyva, Salvatore Calogero Gaglio, María P. Carrasco-Jiménez, Guillermo R. Iglesias, et al.
    Pharmaceutics, 2021
  • Oxyresveratrol-loaded plga nanoparticles inhibit oxygen free radical production by human monocytes: Role in nanoparticle biocompatibility
    Marta Donini, Salvatore Calogero Gaglio, Carlo Laudanna, Massimiliano Perduca, Stefano Dusi
    Molecules, 2021
  • Oxyresveratrol inhibits r848-induced pro-inflammatory mediators release by human dendritic cells even when embedded in plga nanoparticles
    Salvatore Calogero Gaglio, Marta Donini, Piyachat Evelyn Denbaes, Stefano Dusi, Massimiliano Perduca
    Molecules, 2021
  • Complexes of rare earth ions embedded in poly(lactic-co-glycolic acid)(PLGA)nanoparticles: Characterization and spectroscopic study
    Salvatore Calogero Gaglio, Chiara De Rosa, Fabio Piccinelli, Alessandro Romeo, Massimiliano Perduca
    Optical Materials, 2019

RECENT SCHOLAR PUBLICATIONS

  • Extracellular vesicles from long COVID patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation
    L Dalle Carbonare, A Minoia, S Zouari, M Braggio, M Cominacini, ...
    Cell Communication and Signaling 23 (1), 508 , 2025
    2025
    Citations: 3
  • Evaluation of biocontrol measures to reduce bacterial load and healthcare-associated infections
    A Vareschi, SC Gaglio, K Dervishi, A Minoia, G Zanella, L Lucchi, ...
    Microorganisms 13 (8), 1923 , 2025
    2025
    Citations: 3
  • Magnetic hyperthermia drastically enhances killing of Mycobacterium tuberculosis by bacteriocin AS-48 grafted on biomimetic nanoparticles
    M Jimenez-Carretero, AB Gómez, M Lázaro, AC Millán-Placer, SC Gaglio, ...
    International Journal of Biological Macromolecules 319, 145441 , 2025
    2025
    Citations: 3
  • Enhanced Stability and Photochemical Activity of Photosystem I from the Green Alga Chlamydomonas reinhardtii Upon Encapsulation in Organic Matrixes
    SC Gaglio, G Zanella, S Cazzaniga, N Olivieri, E Battagini, A Romeo, ...
    ACS Sustainable Chemistry & Engineering 13 (13), 5046-5056 , 2025
    2025
    Citations: 3
  • Effect of TAT-PLGA-DOx transported by biomimetic magnetic nanoparticles under magnetic hyperthermia and photothermia irradiation
    SC Gaglio, Y Jabalera, A Sola-Leyva, MP Carrasco Jimenez, GR Iglesias, ...
    NALS 2024, 74-74 , 2024
    2024
  • Avoiding undesired effects in the interaction of nanostructures with immune cells: the Role of Oxyresveratrol
    SC Gaglio, M Donini, PE Denbaes, S Dusi, M Perduca
    NALS 2024, 114-114 , 2024
    2024
    Citations: 1
  • Purification and Biochemical Characterization of novel galectin from black poplar mushroom Cyclocybe cylindracea (Agaricomycetes) Strain MEST42 Grown in Algeria
    T Mohammed Esseddik, K Fethi Farouk, R Redouane, D Imene, ...
    INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS 26 (2), 57-70 , 2024
    2024
  • Efficiency of chitosan nanocarriers in vaccinology for mucosal immunization
    SC Gaglio, M Perduca, D Zipeto, G Bardi
    Vaccines 11 (8), 1333 , 2023
    2023
    Citations: 31
  • Ln (III) Complexes Embedded in Biocompatible PLGA Nanoparticles as Potential Vis-to-NIR Optical Probes
    F Piccinelli, S Mizzoni, G Zanella, SC Gaglio, M Perduca, A Romeo, ...
    Molecules 28 (5), 2251 , 2023
    2023
    Citations: 2
  • Effects of magnetic nanoparticles on the functional activity of human monocytes and dendritic cells
    M Donini, F Pettinella, G Zanella, SC Gaglio, C Laudanna, ...
    International Journal of Molecular Sciences 24 (2), 1358 , 2023
    2023
    Citations: 15
  • Improving bioavailability of insoluble payloads through PLGA nanotechnology
    SC Gaglio
    2023
  • Embedding biomimetic magnetic nanoparticles coupled with peptide AS-48 into PLGA to treat intracellular pathogens
    SC Gaglio, Y Jabalera, M Montalbán-López, AC Millán-Placer, ...
    Pharmaceutics 14 (12), 2744 , 2022
    2022
    Citations: 15
  • Near Infrared Circularly Polarized Luminescence From Water Stable Organic Nanoparticles Containing a Chiral Yb (III) Complex
    E Cavalli, C Nardon, OG Willis, F Zinna, L Di Bari, S Mizzoni, S Ruggieri, ...
    Chemistry–A European Journal 28 (37), e202200574 , 2022
    2022
    Citations: 19
  • Fisetin: An integrated approach to identify a strategy promoting osteogenesis
    L Dalle Carbonare, J Bertacco, SC Gaglio, A Minoia, M Cominacini, ...
    Frontiers in Pharmacology 13, 890693 , 2022
    2022
    Citations: 15
  • Enhanced cytotoxic effect of TAT–PLGA-embedded DOXO carried by biomimetic magnetic nanoparticles upon combination with magnetic hyperthermia and photothermia
    Y Jabalera, A Sola-Leyva, SC Gaglio, MP Carrasco-Jiménez, GR Iglesias, ...
    Pharmaceutics 13 (8), 1168 , 2021
    2021
    Citations: 16
  • Oxyresveratrol-loaded PLGA nanoparticles inhibit oxygen free radical production by human monocytes: role in nanoparticle biocompatibility
    M Donini, SC Gaglio, C Laudanna, M Perduca, S Dusi
    Molecules 26 (14), 4351 , 2021
    2021
    Citations: 19
  • Oxyresveratrol inhibits R848-induced pro-inflammatory mediators release by human dendritic cells even when embedded in PLGA nanoparticles
    SC Gaglio, M Donini, PE Denbaes, S Dusi, M Perduca
    Molecules 26 (8), 2106 , 2021
    2021
    Citations: 10
  • Characterization of Cytotoxic Lactose Binding Lectin from Sulphur Polypore, Laetiporus sulphureus (Agaricomycetes), from Algeria
    ME Toumi, M Perduca, Y Necib, FF Kebaili, M Toumi, I Torche, SC Gaglio, ...
    International Journal of Medicinal Mushrooms 23 (11) , 2021
    2021
    Citations: 7
  • Complexes of rare earth ions embedded in poly (lactic-co-glycolic acid)(PLGA) nanoparticles: Characterization and spectroscopic study
    SC Gaglio, C De Rosa, F Piccinelli, A Romeo, M Perduca
    Optical Materials 94, 249-256 , 2019
    2019
    Citations: 11

MOST CITED SCHOLAR PUBLICATIONS

  • Efficiency of chitosan nanocarriers in vaccinology for mucosal immunization
    SC Gaglio, M Perduca, D Zipeto, G Bardi
    Vaccines 11 (8), 1333 , 2023
    2023
    Citations: 31
  • Near Infrared Circularly Polarized Luminescence From Water Stable Organic Nanoparticles Containing a Chiral Yb (III) Complex
    E Cavalli, C Nardon, OG Willis, F Zinna, L Di Bari, S Mizzoni, S Ruggieri, ...
    Chemistry–A European Journal 28 (37), e202200574 , 2022
    2022
    Citations: 19
  • Oxyresveratrol-loaded PLGA nanoparticles inhibit oxygen free radical production by human monocytes: role in nanoparticle biocompatibility
    M Donini, SC Gaglio, C Laudanna, M Perduca, S Dusi
    Molecules 26 (14), 4351 , 2021
    2021
    Citations: 19
  • Enhanced cytotoxic effect of TAT–PLGA-embedded DOXO carried by biomimetic magnetic nanoparticles upon combination with magnetic hyperthermia and photothermia
    Y Jabalera, A Sola-Leyva, SC Gaglio, MP Carrasco-Jiménez, GR Iglesias, ...
    Pharmaceutics 13 (8), 1168 , 2021
    2021
    Citations: 16
  • Effects of magnetic nanoparticles on the functional activity of human monocytes and dendritic cells
    M Donini, F Pettinella, G Zanella, SC Gaglio, C Laudanna, ...
    International Journal of Molecular Sciences 24 (2), 1358 , 2023
    2023
    Citations: 15
  • Embedding biomimetic magnetic nanoparticles coupled with peptide AS-48 into PLGA to treat intracellular pathogens
    SC Gaglio, Y Jabalera, M Montalbán-López, AC Millán-Placer, ...
    Pharmaceutics 14 (12), 2744 , 2022
    2022
    Citations: 15
  • Fisetin: An integrated approach to identify a strategy promoting osteogenesis
    L Dalle Carbonare, J Bertacco, SC Gaglio, A Minoia, M Cominacini, ...
    Frontiers in Pharmacology 13, 890693 , 2022
    2022
    Citations: 15
  • Complexes of rare earth ions embedded in poly (lactic-co-glycolic acid)(PLGA) nanoparticles: Characterization and spectroscopic study
    SC Gaglio, C De Rosa, F Piccinelli, A Romeo, M Perduca
    Optical Materials 94, 249-256 , 2019
    2019
    Citations: 11
  • Oxyresveratrol inhibits R848-induced pro-inflammatory mediators release by human dendritic cells even when embedded in PLGA nanoparticles
    SC Gaglio, M Donini, PE Denbaes, S Dusi, M Perduca
    Molecules 26 (8), 2106 , 2021
    2021
    Citations: 10
  • Characterization of Cytotoxic Lactose Binding Lectin from Sulphur Polypore, Laetiporus sulphureus (Agaricomycetes), from Algeria
    ME Toumi, M Perduca, Y Necib, FF Kebaili, M Toumi, I Torche, SC Gaglio, ...
    International Journal of Medicinal Mushrooms 23 (11) , 2021
    2021
    Citations: 7
  • Extracellular vesicles from long COVID patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation
    L Dalle Carbonare, A Minoia, S Zouari, M Braggio, M Cominacini, ...
    Cell Communication and Signaling 23 (1), 508 , 2025
    2025
    Citations: 3
  • Evaluation of biocontrol measures to reduce bacterial load and healthcare-associated infections
    A Vareschi, SC Gaglio, K Dervishi, A Minoia, G Zanella, L Lucchi, ...
    Microorganisms 13 (8), 1923 , 2025
    2025
    Citations: 3
  • Magnetic hyperthermia drastically enhances killing of Mycobacterium tuberculosis by bacteriocin AS-48 grafted on biomimetic nanoparticles
    M Jimenez-Carretero, AB Gómez, M Lázaro, AC Millán-Placer, SC Gaglio, ...
    International Journal of Biological Macromolecules 319, 145441 , 2025
    2025
    Citations: 3
  • Enhanced Stability and Photochemical Activity of Photosystem I from the Green Alga Chlamydomonas reinhardtii Upon Encapsulation in Organic Matrixes
    SC Gaglio, G Zanella, S Cazzaniga, N Olivieri, E Battagini, A Romeo, ...
    ACS Sustainable Chemistry & Engineering 13 (13), 5046-5056 , 2025
    2025
    Citations: 3
  • Ln (III) Complexes Embedded in Biocompatible PLGA Nanoparticles as Potential Vis-to-NIR Optical Probes
    F Piccinelli, S Mizzoni, G Zanella, SC Gaglio, M Perduca, A Romeo, ...
    Molecules 28 (5), 2251 , 2023
    2023
    Citations: 2
  • Avoiding undesired effects in the interaction of nanostructures with immune cells: the Role of Oxyresveratrol
    SC Gaglio, M Donini, PE Denbaes, S Dusi, M Perduca
    NALS 2024, 114-114 , 2024
    2024
    Citations: 1
  • Effect of TAT-PLGA-DOx transported by biomimetic magnetic nanoparticles under magnetic hyperthermia and photothermia irradiation
    SC Gaglio, Y Jabalera, A Sola-Leyva, MP Carrasco Jimenez, GR Iglesias, ...
    NALS 2024, 74-74 , 2024
    2024
  • Purification and Biochemical Characterization of novel galectin from black poplar mushroom Cyclocybe cylindracea (Agaricomycetes) Strain MEST42 Grown in Algeria
    T Mohammed Esseddik, K Fethi Farouk, R Redouane, D Imene, ...
    INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS 26 (2), 57-70 , 2024
    2024
  • Improving bioavailability of insoluble payloads through PLGA nanotechnology
    SC Gaglio
    2023