VIJAY TRIPATHI
@shuats.edu.in
Assistant Professor
SAM HIGGINBOTTOM UNIVERSITY OF AGRICULTURE TECHNOLOGY AND SCIENCES
RESEARCH, TEACHING, or OTHER INTERESTS
Agricultural and Biological Sciences, Molecular Biology, Water Science and Technology, Microbiology
Scopus Publications
Scopus Publications
Rachan Karmakar, Vijay Tripathi, Pradeep Kumar Sharma, Sourish Bhattacharya, Narpinder Singh, and Suman Naithani
Action For Sustainable Efficacious Development and Awareness
Scientific evidence has demonstrated that biofuels have the ability to reduce environmental contamination, hence addressing the underlying causes of potential disasters. Renewable fuels produced from biological resources provide flexible solutions for several aspects of crisis management, such as supplying energy for emergency generators, fuelling transportation fleets, and offering heating and cooking options. Empirical evidence supports the notion that biofuels effectively reduce carbon and sulphur emissions. Notably, certain biofuels, such as algal biodiesel, have the capacity to mitigate 0.6% of carbon dioxide output. Cities, such as Delhi, that are contaminated by the consumption of fossil fuels have a scarcity of breathing oxygen during the winter and elevated ambient temperatures during the summer. These pioneers cause inundation and tempests in vulnerable regions. The lessons acquired from various locations highlight the importance of cooperation, enhancing capabilities, and providing governmental support in order to replicate and expand successful models. To optimize the advantages of biofuels in crisis management, it is crucial to prioritize research and development projects, involve stakeholders, and raise awareness. The role of national and international policy is vital in providing incentives for the production and use of biofuels, while technical advancements are key in shaping the future of sustainability and efficiency. Communities may utilize the ideas of sustainability and resilience to leverage the transformational potential of biofuels in order to construct societies that are safer, more environmentally friendly, and better equipped to withstand challenges.
Rajesh Kumar, Gaurav Singh Bhoj, Mahesh Chandra Arya, Rachan Karmakar, Pradeep Kumar Sharma, and Vijay Tripathi
Action For Sustainable Efficacious Development and Awareness
This study presents a novel approach to synthesize zinc oxide (ZnO) nanoparticles using a polymer precursor method, offering precise control over particle size in the nanometer scale. Zinc oxide nanoparticles are of significant interest due to their wide-ranging applications in various fields such as solar cells, gas sensors, photocatalysts, and nanomedicines. The synthesized nanoparticles were thoroughly characterized using X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), and Fourier Transform Infrared spectroscopy (FTIR). The distinct hexagonal form detected in the XRD pattern, featuring characteristic reflection planes at angles of 31.72° (100), 34.39° (002), 36.23° (101), and 47.44° (102), signifies the synthesis of ZnO possessing a hexagonal wurtzite structure. The SEM and TEM images revealed uniformly spherical particles with an average size ranging from 35 to 40 nm. Such uniform morphology and size distribution are critical for ensuring consistent performance in applications such as gas sensing and catalysis. Additionally, the FTIR spectra indicated a reduction in impurities after the synthesis process, highlighting the effectiveness of the polymer precursor method in producing high-quality ZnO nanoparticles. Heating the ZnO precursor material at 400°C for 2 hours significantly reduces impurities, suggesting conversion to ZnO nanoparticles.
Arun Kumar Pal, Pooja Tripathi, Jonathan A. Lal, and Vijay Tripathi
Springer Science and Business Media LLC
Sweta Upadhyay, Pradeep Kumar Sharma, Kanika Dogra, Prosun Bhattacharya, Manish Kumar, Vijay Tripathi, and Rachan Karmakar
Elsevier BV
Anugya Jaiswal, Aquib Khan, Akanksha Yogi, Sweta Singh, Arun Kumar Pal, Ramendra Soni, Pooja Tripathi, Jonathan A. Lal, and Vijay Tripathi
Springer Science and Business Media LLC
Amantika Singh, Pooja Singh, Jayant Kashyap, Pooja Tripathi, Krishna Kumar Choudhary, Pradeep Kumar Sharma, Rachan Karmakar, Maulin P. Shah, and Vijay Tripathi
Springer Science and Business Media LLC
Kumar Shreshtha, Satyam Raj, Arun Kumar Pal, Pooja Tripathi, Krishna Kumar Choudhary, Debasis Mitra, Anju Rani, Sergio de los Santos-Villalobos, and Vijay Tripathi
Elsevier BV
Pooja Tripathi, Riya Render, Sweta Nidhi, and Vijay Tripathi
Springer Science and Business Media LLC
Shubham Yadav, Pallavi Kumari, Aditi Sinha, Vijay Tripathi, and Vaibhav Saran
Springer Science and Business Media LLC
Shubham Yadav, Vijay Tripathi, and Vaibhav Saran
Elsevier BV
Uttpal Anand, Tarun Pal, Niraj Yadav, Vipin Kumar Singh, Vijay Tripathi, Krishna Kumar Choudhary, Awadhesh Kumar Shukla, Kumari Sunita, Ajay Kumar, Elza Bontempi,et al.
Springer Science and Business Media LLC
AbstractGlobally, substantial research into endophytic microbes is being conducted to increase agricultural and environmental sustainability. Endophytic microbes such as bacteria, actinomycetes, and fungi inhabit ubiquitously within the tissues of all plant species without causing any harm or disease. Endophytes form symbiotic relationships with diverse plant species and can regulate numerous host functions, including resistance to abiotic and biotic stresses, growth and development, and stimulating immune systems. Moreover, plant endophytes play a dominant role in nutrient cycling, biodegradation, and bioremediation, and are widely used in many industries. Endophytes have a stronger predisposition for enhancing mineral and metal solubility by cells through the secretion of organic acids with low molecular weight and metal-specific ligands (such as siderophores) that alter soil pH and boost binding activity. Finally, endophytes synthesize various bioactive compounds with high competence that are promising candidates for new drugs, antibiotics, and medicines. Bioprospecting of endophytic novel secondary metabolites has given momentum to sustainable agriculture for combating environmental stresses. Biotechnological interventions with the aid of endophytes played a pivotal role in crop improvement to mitigate biotic and abiotic stress conditions like drought, salinity, xenobiotic compounds, and heavy metals. Identification of putative genes from endophytes conferring resistance and tolerance to crop diseases, apart from those involved in the accumulation and degradation of contaminants, could open new avenues in agricultural research and development. Furthermore, a detailed molecular and biochemical understanding of endophyte entry and colonization strategy in the host would better help in manipulating crop productivity under changing climatic conditions. Therefore, the present review highlights current research trends based on the SCOPUS database, potential biotechnological interventions of endophytic microorganisms in combating environmental stresses influencing crop productivity, future opportunities of endophytes in improving plant stress tolerance, and their contribution to sustainable remediation of hazardous environmental contaminants. Graphical Abstract
Nirdesh Kumar Ravi, Pawan Kumar Jha, Kriti Varma, Piyush Tripathi, Sandeep Kumar Gautam, Kirpa Ram, Manish Kumar, and Vijay Tripathi
Elsevier BV
Sweta Nidhi, Pooja Tripathi, and Vijay Tripathi
Springer Science and Business Media LLC
Saumya Tewari, Munish Kumar Mishra, Vijay Tripathi, and Vaibhav Saran
Diva Enterprises Private Limited
Abhijeet W. Singh, Ramendra Soni, Arun Kumar Pal, Pooja Tripathi, Jonathan A. Lal, and Vijay Tripathi
Elsevier
Tarun Pal, Uttpal Anand, Shreya Sikdar Mitra, Protha Biswas, Vijay Tripathi, Jarosław Proćków, Abhijit Dey, and José M. Pérez de la Lastra
Informa UK Limited
Since the end of February 2020, the world has come to a standstill due to the virus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Since then, the global scientific community has explored various remedies and treatments against this virus, including natural products that have always been a choice because of their many benefits. Various known phytochemicals are well documented for their antiviral properties. Research is being carried out to discover new natural plant products or existing ones as a treatment measure for this disease. The three important targets in this regard are-papain like protease (PLpro), spike protein, and 3 chymotrypsin like proteases (3CLpro). Various docking studies are also being elucidated to identify the phytochemicals that modulate crucial proteins of the virus. The paper is simultaneously a comprehensive review that covers recent advances in the domain of the effect of various botanically derived natural products as an alternative treatment approach against Coronavirus Disease 2019 (COVID-19). Furthermore, the docking analyses revealed that rutin (inhibitor of the major protease of SARS-CoV-2), gallocatechin (e.g., interacting with 03 hydrogen bonds with a spike-like protein), lycorine (showing the best binding affinity with amino acids GLN498, THR500 and GLY446 of the spike-like protein), and quercetrin (inhabiting at its residues ASP216, PHE219, and ILE259) are promising inhibitors of SARS‑CoV‑2.Communicated by Ramaswamy H. Sarma.
Deeksha Tiwari, Gaurava Srivastava, Omkar Indari, Vijay Tripathi, Mohammad Imran Siddiqi, and Hem Chandra Jha
Informa UK Limited
Recent reports suggest that persistent Epstein-Barr virus (EBV) infection and its recurrent reactivation could instigate the formation of proteinaceous plaques in the brain: a hallmark of Alzheimer's disease (AD). Interestingly, a major genetic risk factor of AD, the apolipoprotein E (ApoE), could also influence the outcome of EBV infection in an individual. The ApoE is believed to influence the proteinaceous plaque clearance from the brain, and its defective functioning could result in the aggregate deposition. The persistent presence of EBV infection in a genetically predisposed individual could create a perfect recipe for severe neurodegenerative consequences. Therefore, in the present study, we investigated the possible interactions between ApoE and various EBV proteins using computational tools. Our results showed possibly stable de-novo interactions between the C-terminal domain of ApoE3 and EBV proteins: EBV nuclear antigen-1 (EBNA1) and BamHI Z fragment leftward open reading frame-1 (BZLF1). The EBNA1 protein of EBV plays a crucial role in establishing latency and replication of the virus. Whereas BZLF1 is involved in the lytic replication cycle. The proposed interaction of EBV proteins at the ligand-binding site of ApoE3 on CTD could interfere with- its capability to sequester amyloid fragments and, hence their clearance from the brain giving rise to AD pathology. This study provides a new outlook on EBV's underexplored role in AD development and paves the way for novel avenues of investigation which could further our understanding of AD pathogenesis.Communicated by Ramaswamy H. Sarma[Figure: see text].
Nirdesh Kumar Ravi, Arun Kumar Pal, Ramendra Soni, Pooja Tripathi, Anjali Singhal, Pawan Kumar Jha, and Vijay Tripathi
IWA Publishing
Abstract Excessive anthropogenic activities play a significant role in the emergence and dissemination of antibiotic resistance in urban streams and river sediment. The objectives of the present study were to investigate the antibiotic susceptibility profile, molecular detection of antibiotic resistance genes (ARGs), and identification of multidrug-resistant bacterial isolates in the mainstream and tributaries of the Ghaghara River. The obtained data indicated that the majority of the isolates were identified as Bacillus spp. (40%) followed by Klebsiella quasipneumoniae (20%), Exiguobacterium undae (13.33%). Most of the bacterial isolates were resistant against penicillin G (P) (24%), cefuroxime (CXM) (20%), amoxicillin (AMX) (18%), and ampicillin (AMP) (17%) in sediments samples, whereas penicillin G (27%), cefuroxime (CXM) and erythromycin (E) was 13%, AMP and cefaclor both showed 12% in water samples respectively. This study provides insight into the prevalence of multiple antibiotic-resistant bacterial diversity in the Ghaghara River and provides the route to disseminate the multidrug-resistant pathogens in the human and animal population through the aquatic environment.
Denis Horgan, Rizwana Mia, Tosan Erhabor, Yosr Hamdi, Collet Dandara, Jonathan A. Lal, Joel Fokom Domgue, Oladimeji Ewumi, Teresia Nyawira, Salomé Meyer,et al.
MDPI AG
Tackling cancer is a major challenge right on the global level. Europe is only the tip of an iceberg of cancer around the world. Prosperous developed countries share the same problems besetting Europe–and the countries and regions with fewer resources and less propitious conditions are in many cases struggling often heroically against a growing tide of disease. This paper offers a view on these geographically wider, but essentially similar, challenges, and on the prospects for and barriers to better results in this ceaseless battle. A series of panels have been organized by the European Alliance for Personalised Medicine (EAPM) to identify different aspects of cancer care around the globe. There is significant diversity in key issues such as NGS, RWE, molecular diagnostics, and reimbursement in different regions. In all, it leads to disparities in access and diagnostics, patients’ engagement, and efforts for a better understanding of cancer.
Ajay Kumar, Sandeep Kumar Singh, Vipin Kumar Singh, Chandra Kant, Amit Kishore Singh, Vijay Tripathi, Kalpna Singh, Vijay Kumar Sharma, and Joginder Singh
Elsevier BV
Ramendra Soni, Arun Kumar Pal, Pooja Tripathi, Pawan Kumar Jha, and Vijay Tripathi
IWA Publishing
Abstract The inadequate practice of discharge of wastewater into receiving water bodies alters physicochemical parameters, which ultimately disturbs the livelihood of aquatic flora and fauna. The present study was focussed on the evaluation of the efficiencies of wastewater treatment plants based on different technologies through analysing the physicochemical parameters of wastewater collected from each treatment step including inlet, outlet and downstream Ganges River in Prayagraj, Varanasi and Kanpur (India) during winter and summer seasons. The removal efficiency of the MBBR technology of Prayagraj WWTP was observed to be better than that of the ASP and UASB technologies of Varanasi and Kanpur respectively for both seasons. Correlation analysis explained the strong negative correlation of pH and DO with nearly all the parameters of the study; whereas TDS, hardness, ammonia and BOD were highly correlated with each other in each city. The factor analysis suggested the best fit amongst the physicochemical parameters, with four factors elucidating 78.00% of the total variance, which further explained that DO, TDS, total alkalinity, nitrate, COD, and temperature were the major components for pollution. The results indicated that most of the samples were not appropriate for direct discharge into water bodies and irrigation purposes and thus needed further implementation of advanced technologies in their treatment procedure.
Uttpal Anand, Champa Keeya Tudu, Samapika Nandy, Kumari Sunita, Vijay Tripathi, Gary J. Loake, Abhijit Dey, and Jarosław Proćków
Elsevier BV
Raches Ella, Siddarth Reddy, William Blackwelder, Varsha Potdar, Pragya Yadav, Vamshi Sarangi, Vinay K Aileni, Suman Kanungo, Sanjay Rai, Prabhakar Reddy,et al.
Elsevier BV
Pradeep Kumar, Dipendra Kumar Mahato, Madhu Kamle, Rituraj Borah, Bharti Sharma, Shikha Pandhi, Vijay Tripathi, Hardeo Singh Yadav, Sheetal Devi, Umesh Patil,et al.
Wiley
Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational and medicinal purposes. In many countries, cannabis-based medicines have been legalized under certain conditions because of their immense prospects in medicinal applications. With a comprehensive insight into the prospects and challenges associated with the pharmacological use and global trade of C. sativa, this mini-review focuses on the medicinal importance of the plant and its legal status worldwide; the pharmacological compounds and its therapeutic potential along with the underlying public health concerns and future perspective are herein discussed. The existence of major compounds including Δ9 -tetrahydrocannabinol (Δ9 -THC), cannabidiol, cannabinol, and cannabichromene contributes to the medicinal effects of the cannabis plant. These compounds are also involved in the treatment of various types of cancer, epilepsy, and Parkinson's disease displaying several mechanisms of action. Cannabis sativa is a plant with significant pharmacological potential. However, several aspects of the plant need an in-depth understanding of the drug mechanism and its interaction with other drugs. Only after addressing these health concerns, legalization of cannabis could be utilized to its full potential as a future medicine.