Dr. Jitender Kumar
@cuhimachal.ac.in
Assistant Professor
Central University of Himachal Pradesh
Dr. Jitender Kumar
Assistant Professor
Department of Plant Sciences
Central University of Himachal Pradesh
Dharamshala, District- Kangra
Contact No.: - +91 6283767612, +91 9418393796
Email: - jitenderkumarcuhp@
EDUCATION
Ph.D.
M.Sc.
RESEARCH, TEACHING, or OTHER INTERESTS
Plant Science, Agricultural and Biological Sciences, Forestry, Horticulture
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Jitender Kumar, Diksha Katoch, Ambika Thakur, Arpit Pathania, Apurav Anand, Kajal Choudhary, and Shelja Shelja
Open Science Publishers LLP
Orchids are the most diverse and valuable plants in the world. These are the major constituents of traditional Chinese medicine. Horticulturists and collectors highly value them due to their esthetic appeal and cultural significance. However, many orchids risk extinction due to habitat loss, over-collection, and other human activities. To address this issue, various conservation strategies have been developed and implemented. This review paper focuses on the orchids’ conservation status, threats, and conservation measures. Habitat conservation allows the long-term existence of life on Earth. The conservation efforts involve a combination of in situ and ex situ measurements. The in situ maintenance involves protecting the natural habitats where orchids grow, such as establishing protected areas and restoring degraded habitats. The ex situ measures include cultivating and preserving orchids outside their natural habitats, such as botanical gardens, seed banks, and cryopreservation.
Amandeep Dogra and Jitender Kumar
Frontiers Media SA
Cancer is a severe health issue, and cancer cases are rising yearly. New anticancer drugs have been developed as our understanding of the molecular mechanisms behind diverse solid tumors, and metastatic malignancies have increased. Plant-derived phytochemical compounds target different oncogenes, tumor suppressor genes, protein channels, immune cells, protein channels, and pumps, which have attracted much attention for treating cancer in preclinical studies. Despite the anticancer capabilities of these phytochemical compounds, systemic toxicity, medication resistance, and limited absorption remain more significant obstacles in clinical trials. Therefore, drug combinations of new phytochemical compounds, phytonanomedicine, semi-synthetic, and synthetic analogs should be considered to supplement the existing cancer therapies. It is also crucial to consider different strategies for increased production of phytochemical bioactive substances. The primary goal of this review is to highlight several bioactive anticancer phytochemical compounds found in plants, preclinical research, their synthetic and semi-synthetic analogs, and clinical trials. Additionally, biotechnological and metabolic engineering strategies are explored to enhance the production of bioactive phytochemical compounds. Ligands and their interactions with their putative targets are also explored through molecular docking studies. Therefore, emphasis is given to gathering comprehensive data regarding modern biotechnology, metabolic engineering, molecular biology, and in silico tools.