Badea Nicoleta

Scopus Publications

Dual Arnica montana and Ruscus aculeatus Hyaluronic Acid-Modified Nanostructured Lipid Carriers for Accelerated Wound Healing Effect
Ioana Lăcătusu, Robert Tincu, Mihaela Bacalum, Diana Lavinia Stan, Ovidiu Cristian Oprea, et al.
Antioxidants, 2026
Skin wound healing involves a delicate balance between proliferation and remodelling processes, with significant therapeutic challenges. The present work aimed to investigate the capacity of hybrid lipid nanocarriers carrying a complex phytochemical profile (HA-NLC-ArnicaM and/or RuscusA extracts) to counteract the destructive action of oxidative free radicals and to accelerate wound closure induced on BJ fibroblast cells. The lipid and hybrid nanocarriers have main diameters ranging from 145 nm to 180 nm, electrokinetic potential between −45 mV and −62 mV, and entrapment efficiency of plant extracts exceeding 96%. HA-NLC-plant extracts exhibit an appropriate level of biocompatibility at concentrations < 50 µg/mL. ArnicaM wins the antioxidant contest while RuscusA proved excellent for accelerating the wound closure process. NLCs and HA-NLCs entrapping ArnicaM manifested the highest capacity to neutralise DPPH free radicals, reaching 79.4% inhibition. BJ fibroblast cells treated with HA-NLCs closed the wound more rapidly than NLCs, with cells reaching maximum wound closure efficiency when treated with 12.5 and 100 µg/mL HA-NLC-RuscusA, followed by HA-NLC-ArnicaM-RuscusA. These results facilitate the design of remarkable hybrid lipid nanocarriers, which exploit the emergence of a pharmacological phytochemical’s synergy, and which could contribute to stimulating signalling pathways and promoting appropriate cellular regeneration, needed for wound healing.
Advanced Hybrid Polysaccharide—Lipid Nanocarriers for Bioactivity Improvement of Phytochemicals from Centella asiatica and Hypericum perforatum
Ioana Lăcătusu, Mihaela Bacalum, Diana Lavinia Stan, Ovidiu-Cristian Oprea, Mihaela Neagu, et al.
Pharmaceutics, 2026
Background/Objectives: Phytochemicals are known to be active contributors to a healthy life, providing valuable wound healing benefits. Methods: This research took an innovative approach that successfully overcame the bioavailability limits of herbal extracts, by entrapping CentellaA with HypericumP in nanostructured lipid carriers (NLCs) and hybrid hyaluronic acid (HA-NLCs) as valuable formulations with enhanced bioactivity. Results: NLCs and HA-NLCs showed excellent entrapping efficiency values for CentellaA and HypericumP ranging from 89.5 to 95.3%. Co-entrapping of CentellaA:HypericumP in a weight ratio of 4:1 and 2:1 led to diameters of 221.4 ± 2.08 nm for NLC-CentellaA-HypericumP and 220.3 ± 1.74 nm for hybrid HA-NLC-CentellaA-HypericumP. The bimodal calorimetric profile of NLCs contributed to a lower degree of lipid core structural organization. HA-NLC-CentellaA showed the safest biocompatibility behavior with BJ skin cells. Conclusions: The cells treated with NLC-CentellaA exhibited a favorable scratch wound closure and promoted the fastest BJ cell migration. NLC- and HA-NLC herbal extracts remodeled the cytoskeleton of BJ fibroblast cells. The morphological fluorescence changes revealed that the fibroblast cells retained intact their cytoskeleton, characteristic of a viable cell with no obvious stress. An active motility of cells treated with NLCs in the wound area was detected, indicating strong pro-migratory properties; e.g., for NLC-CentellaA, the wound was almost closed after 30 h. Designing NLCs with HA adaptability to reinforce the skin wound healing action represents a desired step for the development of herbal products that meets the challenge of combining the benefits of phytochemicals and nanotechnology to create value-added herbal products.
Antimicrobial Efficacy of Green Silver Nanoparticles Synthesized Using Crataegus monogyna Extract
Mihaela Cristina Lite, Roxana Constantinescu, Laura Chirilă, Alina Popescu, Andrei Kuncser, et al.
Biomimetics, 2025
Current demands in the field of functional textiles include the integration of specific characteristics, such as self-cleaning, antimicrobial efficacy and possible wound healing properties. Green synthesis of nanoparticles represents a promising strategy to address these challenges, combining biocompatibility and ecological safety with effective antimicrobial and antioxidant performance. In this study, silver nanoparticles (AgNPs) have been synthesized using different ratios of Crataegus monogyna extract: AgNO3. Physically stable AgNPs with spherical shape, particle main diameters ranging from 61.9 to 85.4 nm and appropriate polydispersity indices were produced. Crataegus monogyna presented high phenolic content (30.58 ± 2.20 mg/g) and strong antioxidant activity (96 ± 1.6 µmol TE/g). The obtained nanoparticles were characterized by TEM, EDX, and XRD analysis. When applied to cotton and wool textiles, the AgNPs adhered uniformly, caused minimal colour change, and exhibited enhanced antimicrobial activity against bacterial and fungal strains compared to other plant-derived AgNPs, with values between 8 and 13.5 mm. The treated textiles demonstrated strong performance against Staphylococcus aureus with inhibition zones of 11 ± 0.53 for cotton and 13.5 ± 0.42 for wool. These findings highlight the potential of Crataegus monogyna-based AgNPs as effective and fabric-compatible antimicrobial agents.
Ginkgo Biloba and Green Tea Polyphenols Captured into Collagen–Lipid Nanocarriers: A Promising Synergistically Approach for Apoptosis Activation and Tumoral Cell Cycle Arrest
Mirela Mihaila, Nicoleta Badea, Marionela Birliga, Marinela Bostan, Madalina Georgiana Albu Kaya, et al.
International Journal of Molecular Sciences, 2025
Considering the world’s growing interest in health-promoting phytochemicals, the current research investigated the development of a dual-captured Ginkgo Biloba and Green Tea Extract into Collagen-Nanostructured Lipid Nanocarriers (Col-NLC-GBil-GTE) for an enhanced therapeutic efficacy against hepatic, colon or breast cancer. NLC considerably reduced cell viability; the most advanced cytotoxicity profile was determined on human colon adenocarcinoma cells (LoVo) and liver cancer cells (HepG2), e.g., tumor cell viability was 21.81% in the presence of Col-NLC-GBil-GTE, similar to that determined for Cisplatin. Col-NLC exhibited apoptosis in HepG2 and LoVo cells and no significant apoptosis induction in normal HUVECs. A 20% increase in apoptosis for HepG2 cells was registered for 100 μg/mL NLC-GBil-GTE compared to Cisplatin (Cis-Pt), e.g., a 63.4% total apoptosis for NLC-GBil-GTE versus a 52.6 apoptosis induced by 100 μg/mL of a chemotherapeutic drug. According to the cell cycle outcomes, an accumulation of hepatocyte HepG2 tumor cells in the G0/G1 phase was detected upon treatment with 100 mg/mL of NLC- and Col-NLC-GBil-GTE, simultaneously with a drastic decrease in the S phase, which may indicate a cell number reduction that enters in the division cycle. The simultaneous delivery of GBil and GTE by synchronizing their bioactivities offers several advantages; Col-NLC-GBil-GTE can be viewed as a noteworthy strategy for consideration in connection with antitumor therapeutic protocols.
Hybrid Carbohydrate–Lipid Nanocarriers: In Vitro Efficacy Gene-Rated by Association of UV-Absorbers and Raspberry Polyphenols Rich-Fraction
Nicoleta Badea, Diego Samayoa, Alina Moroşan, Cristina Ott, Ioana Lacatusu
Pharmaceuticals, 2025
Background/Objectives: The study aims to investigate an improved version of lipid nanocarriers (NLCs) (formulated with functional coconut butter and marula oil) by designing hyaluronic acid (HA) decorated NLC co-loaded with dual UVA (butyl methoxy dibenzoyl methane, BMDBM), UVB absorbers (ethyl-hexyl-salicylate, EHS) and a Raspberry rich polyphenols fraction (RPRF) for development of more natural NLC-based to-pical formulations. Methods: Quality and quantitative attributes of classic- and HA-NLC have been assigned based on particle size, electrokinetic potential, encapsulation efficiency, spectroscopic characteristics, and high-resolution mass spectrometry. To establish the performance profile of antioxidant activity, release of active substances, sun blocking action, and photostability, in vitro studies were conducted. Results: NLC with an average size of ~150 nm and zeta potentials < −39.5 mV showed 80% and 93.1% of encapsulation efficiency for BMDBM and EHS, and up to 83% for natural RPRF. A long-lasting release of absorbers, with a maximum cumulative release of 2.1% BMDBM and 4.6% EHS was detected. NLC-UV Abs-RPRF-HA assured 72.83% radical scavenging activity. The IC50 for HA-NLC-UV Abs-RPRF was 6.25-fold lower than NLC-UV Abs-HA, which reflects the greater free radical scavenging action. The conditioned NLC–UV Abs-RPRF-HA cream was able to provide a sun protection factor value of 52 and UVA-PF value of 81, which underlines an impressive removal of both categories of UVA and UVB radiation. A significant photoprotective upregulation, four-fold for the topical formulation with NLC-UV Abs-RPRF-HA, resulted after a simulated irradiation process. Conclusions: HA decorated-NLC-conditioned creams might provide a useful platform for developing na-tural and sophisticated dermal delivery systems, for influencing skin permeability, and for synergistically imparting antioxidant and photoprotective actions to cosmetic pro-ducts.
Antimicrobial treatment based on green silver nanoparticles applied to textile heritage
MIHAELA-CRISTINA LITE, RODICA ROXANA CONSTANTINESCU, NICOLETA BADEA, LAURA CHIRILĂ, DOINA TOMA, et al.
Industria Textila, 2025
Nanomaterials science expanded its application in various directions (biomedical, smart materials, sensors, optoelectronics, etc.). Silver nanoparticles (AgNPs) have been intensively tested within the textile department and demonstrated antimicrobial activity when applied under various forms (commercial colloidal nano-silver, in situ synthesis, etc.). The application of silver nanoparticles for historical artefacts conservation has been addressed, and several papers have reported the use of such treatments for cultural heritage conservation. In this work, the historical sample tested consisted of a cotton fabric, part of a priest’s costume, dating back to the 18 th century, provided by the Church of Saint Nicolae “Dintr-o Zi”, located in Bucharest. The piece was treated with AgNPs-based treatment, which was phyto-synthesised by using a plant aqueous extract. The effect of the treatment on the sample was examined by studying fibres of the fabrics with electronic microscopy (SEM) and by quantifying the modification of the sample appearance, using chromatic parameters measurements. The antimicrobial activity was tested against gram-positive and gram-negative bacteria strains, Escherichia coli and Staphylococcus aureus, and the fungal strain Penicillium hirsutum. The layer of silver nanoparticles was uniformly distributed on the surface of the historical textile fibres. The changes in the appearance of the textile were minimal, with a total colour difference of 2.11. Evaluating the antimicrobial activity, superior antifungal performance was observed against the Penicillium hirsutum strain (for which the inhibition zone value was 12.5 mm). The FTIR spectrum demonstrated that the integrity of the textile fibre is maintained following the application of the treatment.
EXPLORING FAT REPLACEMENT IN CHEESE ANALOGUES VIA ¹H-AND ¹³C-NMR SPECTROSCOPY, LIPID NUTRITIONAL DESCRIPTORS, RHEOLOGICAL BEHAVIOR AND COLOR
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2025
Hybrid Albumin-Decorated Lipid-Nanocarrier-Mediated Delivery of Polyphenol-Rich Sambucus nigra L. in a Potential Multiple Antitumoural Therapy
Robert Tincu, Mirela Mihaila, Marinela Bostan, Daniela Istrati, Nicoleta Badea, et al.
International Journal of Molecular Sciences, 2024
The current research attempted to address the suitability of bioactive Sambucus nigra extract entrapped in albumin-decorated nanostructured lipid carriers (NLCs) as a promising “adjuvant” in improving tumour penetration for multiple antitumour therapy. The new hybrid albumin-decorated NLCs were characterised based on, e.g., the particle size, zeta electrokinetic potential, SambucusN entrapment efficiency, and fluorescence spectroscopy and tested for different formulation parameters. The antioxidant activity of NLC-SambucusN was significantly enhanced by a bovine serum albumin (BSA) polymer coating. According to the real-time cell analysis (RTCA) results, NLC-I–SambucusN–BSA behaved similarly to the chemotherapeutic drug, cisplatin, with cell viability for LoVo tumour cells of 21.81 ± 1.18%. The new albumin–NLC–SambucusN arrested cancer cells in G1 and G2 cycles and intensified the apoptosis process in both early and late phases. An advanced induction, over 50% apoptosis in LoVo colon cells, was registered for 50 μg/mL of NLC-II-SambucusN-BSA, a fourfold increase compared to that of untreated cells. RTCA and flow cytometry results showed that concentrations of the hybrid NLC–SambucusN up to 50 μg/mL do not affect the proliferation of normal HUVEC cells. This approach provides insightful information regarding the involvement of phytochemicals in future therapeutic strategies. Albumin-decorated NLCs can be considered a noteworthy strategy to be connected to antitumour therapeutic protocols.
BIOINSPIRED COATINGS BASED ON LIPID NANOCARRIERS FOR TARGETED DRUG DELIVERY
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2024
TiO2 NANOSTRUCTURED SURFACE COATINGS FOR TETRACYCLINE RELEASE
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2024
PRE-FORMULATION, FORMULATION AND PILOT SCALE-UP STUDIES TO ESTABLISH THE QUALITATIVE AND QUANTITATIVE COMPOSITION OF AN INNOVATIVE NANOFORM DIETARY SUPPLEMENT FOR MENOPAUSAL THERAPY
Farmacia, 2024
Y-Branched Titanium Dioxide Nanotubes as a Potential Antimicrobial Coating for Implants
Angela Gabriela Păun, Valeria Petrina, Nicoleta Badea, Camelia Ungureanu, Simona Popescu, et al.
Crystals, 2023
Safety of Innovative Nanotechnology Oral Formulations Loaded with Bioactive Menopause Molecules: Influence of Genotoxicity and Biochemical Parameters on a Menopausal Rat Model
Simona Crișan, Anca Lucia Pop, Ioana Lacatusu, Nicoleta Badea, Cosmin Mustaciosu, et al.
Nutrients, 2023
Phytochemical Synthesis of Silver Nanoparticles and Their Antimicrobial Investigation on Cotton and Wool Textiles
Mihaela Cristina Lite, Roxana Constantinescu, Elena Cornelia Tănăsescu, Andrei Kuncser, Cosmin Romanițan, et al.
Materials, 2023
Polygonum cuspidatum Loaded Nanostructured Lipid Carriers for Dual Inhibition of TNF-α- and IL-6 Cytokines and Free Radical Species
Teodora-Alexandra Iordache, Nicoleta Badea, Mirela Mihaila, Simona Crisan, Anca Lucia Pop, et al.
Materials, 2023
Novel Bovine Serum Albumin-Decorated–Nanostructured Lipid Carriers Able to Modulate Apoptosis and Cell-Cycle Response in Ovarian, Breast, and Colon Tumoral Cells
Robert Tincu, Mirela Mihaila, Marinela Bostan, Florina Teodorescu, Daniela Istrati, et al.
Pharmaceutics, 2023
Burdock-Derived Composites Based on Biogenic Gold, Silver Chloride and Zinc Oxide Particles as Green Multifunctional Platforms for Biomedical Applications and Environmental Protection
Irina Zgura, Nicoleta Badea, Monica Enculescu, Valentin-Adrian Maraloiu, Camelia Ungureanu, et al.
Materials, 2023
Green Synthesis of Advanced Carbon Materials Used as Precursors for Adsorbents Applied in Wastewater Treatment
Georgeta Predeanu, Valerica Slăvescu, Marius Florin Drăgoescu, Niculina Mihaela Bălănescu, Alexandru Fiti, et al.
Materials, 2023
SILVER NANOPARTICLES BASED ON CAFFEIC ACID APPLIED FOR TEXTILES PRESERVATION
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2023
Antimicrobial treatment for textiles based on flavonoid-mediated silver nanoparticles dispersions
MIHAELA-CRISTINA LITE, RODICA ROXANA CONSTANTINESCU, NICOLETA BADEA, ELENA-CORNELIA TĂNĂSESCU, IRINA-MARIANA SĂNDULACHE, et al.
Industria Textila, 2023
COMPARATIVE DISSOLUTION STUDY OF A SOLID PHARMACEUTICAL FORM CONTAINING NANOSTRUCTURED LIPID CARRIER (NLC) INCORPORATING DIOSGENIN – CONVENTIONAL VERSUS BIORELEVANT DISSOLUTION MEDIA
ANCA LUCIA POP
Farmacia, 2023
Design of Green Silver Nanoparticles Based on Primula Officinalis Extract for Textile Preservation
Mihaela Cristina Lite, Rodica Roxana Constantinescu, Elena Cornelia Tănăsescu, Andrei Kuncser, Cosmin Romanițan, et al.
Materials, 2022
Biopolymers as intermediate layers for amoxicillin grafting on antibacterial surface
Angela Gabriela Olaru, Valeria Butculescu, Cristina Dumitriu, Nicoleta Badea, Simona Popescu, et al.
Surfaces and Interfaces, 2022
Optical studies on human hair fibres treated with a natural extract of red tulip flowers
Optoelectronics and Advanced Materials Rapid Communications, 2022
Novel Green Nanotechnologies Applied in Environmental Protection and Health
Marcela-Elisabeta Barbinta-Patrascu, Nicoleta Badea, Irina Zgura
Materials, 2022
Salicin and Hederacoside C-Based Extracts and UV-Absorbers Co-Loaded into Bioactive Lipid Nanocarriers with Promoted Skin Antiaging and Hydrating Efficacy
Ioana Lacatusu, Brindusa Balanuca, Andrada Serafim, Cristina Ott, Mariana Prodana, et al.
Nanomaterials, 2022
Textile artefacts conservation using nanomaterials - Review
MIHAELA CRISTINA LITE, RODICA ROXANA CONSTANTINESCU, ELENA CORNELIA TANASESCU, OVIDIU GEORGE IORDACHE, NICOLETA BADEA
Industria Textila, 2022
THE INFLUENCE OF VEGETABLE OIL AND SELF-ORGANIZING AGENTS’ COMPOSITION ON OBTAINING STABLE NANOSTRUCTURED LIPID CARRIERS
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2022
CURCUMIN CO-LOADED WITH A LIPID MEDIATOR IN THE SAME NANOSTRUCTURED LIPID DELIVERY SYSTEM
LUCIA MARINA CRISTINA COC
Farmacia, 2022
Challenges in coopted hydrophilic and lipophilic herbal bioactives in the same nanostructured carriers for effective bioavailability and anti-inflammatory action
Teodora-Alexandra Iordache, Nicoleta Badea, Mirela Mihaila, Simona Crisan, Anca Lucia Pop, et al.
Nanomaterials, 2021
Multifaced role of dual herbal principles loaded-lipid nanocarriers in providing high therapeutic efficacity
Ioana Lacatusu, Teodora Alexandra Iordache, Mirela Mihaila, Dan Eduard Mihaiescu, Anca Lucia Pop, et al.
Pharmaceutics, 2021
Characterization and antitumoral activity of biohybrids based on turmeric and silver/silver chloride nanoparticles
Marcela-Elisabeta Barbinta-Patrascu, Yulia Gorshkova, Camelia Ungureanu, Nicoleta Badea, Gizo Bokuchava, et al.
Materials, 2021
Biological performances of plasmonic biohybrids based on phyto-silver/silver chloride nanoparticles
Yulia Gorshkova, Marcela-Elisabeta Barbinta-Patrascu, Gizo Bokuchava, Nicoleta Badea, Camelia Ungureanu, et al.
Nanomaterials, 2021
Effective Lipid Nanocarriers Based on Linseed Oil for Delivery of Natural Polyphenolic Active
Lucia Marina Cristina Coc, Ioana Lacatusu, Nicoleta Badea, Marcela Elisabeta Barbinta-Patrascu, Aurelia Meghea
Journal of Nanomaterials, 2021
The association effect of cocoa butter with vegetable oils on the obtaining of lipid nanocarriers loaded with antidepressant and antipsychotic drugs
Aurelia BRATU, Cristina OTT, Brindusa BALANUCA, Nicoleta BADEA, Ioana LACATUSU, et al.
Revue Roumaine De Chimie, 2021
Biophysical aspects of bio-nanosilver generated from Urtica dioica leaves and Vitis vinifera fruits’ extracts
Romanian Reports in Physics, 2021
Azelaic acid-willow bark extract-panthenol – Loaded lipid nanocarriers improve the hydration effect and antioxidant action of cosmetic formulations
Laura Vasilica Arsenie, Ioana Lacatusu, Ovidiu Oprea, Natalita Bordei, Mihaela Bacalum, et al.
Industrial Crops and Products, 2020
Novel ecogenic plasmonic biohybrids as multifunctional bioactive coatings
Marcela Elisabeta Barbinta-Patrascu, Camelia Ungureanu, Nicoleta Badea, Mihaela Bacalum, Andrada Lazea-Stoyanova, et al.
Coatings, 2020
Bioperformances of honey-phytonanosilver in silica materials
Journal of Optoelectronics and Advanced Materials, 2020
Synergism of plant extract and vegetable oils-based lipid nanocarriers: Emerging trends in development of advanced cosmetic prototype products
I. Lacatusu, D. Istrati, N. Bordei, M. Popescu, A.M. Seciu, et al.
Materials Science and Engineering C, 2020
Systems based on carbon nanotubes with potential in cancer therapy
Nicoleta Badea, Mariela Madalina Craciun, Andreea Sofia Dragomir, Mihaela Balas, Anca Dinischiotu, et al.
Materials Chemistry and Physics, 2020
Bioactive phyto-nanosilver particles “green” synthesized from clary sage, burdock, southernwood and asparagus
Romanian Reports in Physics, 2020
The association effect of cocoa butter with vegetable oils on the obtaining of lipid nanocarriers loaded with antidepressant and antipsychotic drugs
Revue Roumaine De Chimie, 2020
Lipo-nanosilver composites biogenerated using Artemisia abrotanum L. aqueous extract
Daniela Besliu, Marcela Elisabeta Barbinta-Patrascu, Nicoleta Badea, Ileana Rau, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2019
3D hybrid structures based on biomimetic membranes and Caryophyllus aromaticus - “green” synthesized nano-silver with improved bioperformances
Marcela Elisabeta Barbinta-Patrascu, Nicoleta Badea, Mihaela Bacalum, Camelia Ungureanu, Ioana Raluca Suica-Bunghez, et al.
Materials Science and Engineering C, 2019
Advanced bioactive lipid nanocarriers loaded with natural and synthetic anti-inflammatory actives
I. Lacatusu, N. Badea, G. Badea, M. Mihaila, C. Ott, et al.
Chemical Engineering Science, 2019
Improved anti-obesity effect of herbal active and endogenous lipids co-loaded lipid nanocarriers: Preparation, in vitro and in vivo evaluation
I. Lacatusu, N. Badea, D. Udeanu, L. Coc, A. Pop, et al.
Materials Science and Engineering C, 2019
Photophysical aspects regarding the effects of Paeonia officinalis flower extract on DNA molecule labelled with methylene blue
Optoelectronics and Advanced Materials Rapid Communications, 2019
Tangerine-generated silver - Silica bioactive materials
Romanian Journal of Physics, 2019
New cosmetic formulations with broad photoprotective and antioxidative activities designed by amaranth and pumpkin seed oils nanocarriers
Ioana Lacatusu, Laura Vasilica Arsenie, Gabriela Badea, Ovidiu Popa, Ovidiu Oprea, et al.
Industrial Crops and Products, 2018
Bio-activity of organic/inorganic phyto-generated composites in bio-inspired systems
Romanian Journal of Physics, 2018
Marigold extract, azelaic acid and black caraway oil into lipid nanocarriers provides a strong anti-inflammatory effect in vivo
I. Lacatusu, G. Badea, M. Popescu, N. Bordei, D. Istrati, et al.
Industrial Crops and Products, 2017
Effect of UV irradiation on biomimetic membranes labelled with bioporphyrins
Marcela Elisabeta Barbinta-Patrascu, Nicoleta Badea, Stefan Marian Iordache, Sanja Milenković Petrović, Ileana Rau
Molecular Crystals and Liquid Crystals, 2017
Photophysical studies on biocomposites based on carbon nanotubes and chlorophyll-loaded biomimetic membranes
Romanian Reports in Physics, 2017
Ecobiophysical Aspects on Nanosilver Biogenerated from Citrus reticulata Peels, as Potential Biopesticide for Controlling Pathogens and Wetland Plants in Aquatic Media
Marcela Elisabeta Barbinta-Patrascu, Nicoleta Badea, Camelia Ungureanu, Stefan Marian Iordache, Marioara Constantin, et al.
Journal of Nanomaterials, 2017
Naringenin improves the sunscreen performance of vegetable nanocarriers
Gabriela Badea, Nicoleta Badea, Lorelei I. Brasoveanu, Mirela Mihaila, Raluca Stan, et al.
New Journal of Chemistry, 2017
Multifunctional soft hybrid bio-platforms based on nano-silver and natural compounds
M.E. Barbinta-Patrascu, N. Badea, C. Pirvu, M. Bacalum, C. Ungureanu, et al.
Materials Science and Engineering C, 2016
Phyto-mediated nanostructured carriers based on dual vegetable actives involved in the prevention of cellular damage
D. Istrati, I. Lacatusu, N. Bordei, G. Badea, O. Oprea, et al.
Materials Science and Engineering C, 2016
Silver-based biohybrids "green" synthesized from Chelidonium majus L.
Marcela Elisabeta Barbinta-Patrascu, Nicoleta Badea, Camelia Ungureanu, Marioara Constantin, Cristian Pirvu, et al.
Optical Materials, 2016
Gold and silver geranium biocomposites
Marcela Elisabeta Barbinta Patrascu, Nicoleta Badea, Camelia Ungureanu, Ioana Bunghez Raluca, Ileana Rau
Molecular Crystals and Liquid Crystals, 2016
Ivy leaves extract based - Lipid nanocarriers and their bioefficacy on antioxidant and antitumor activities
I. Lacatusu, N. Badea, G. Badea, L. Brasoveanu, R. Stan, et al.
Rsc Advances, 2016
Exploitation of amaranth oil fractions enriched in squalene for dual delivery of hydrophilic and lipophilic actives
Cristina Ott, Ioana Lacatusu, Gabriela Badea, Iulia Adriana Grafu, Daniela Istrati, et al.
Industrial Crops and Products, 2015
Lipid nanocarriers based on natural oils with high activity against oxygen free radicals and tumor cell proliferation
I. Lacatusu, N. Badea, G. Badea, O. Oprea, M.A. Mihaila, et al.
Materials Science and Engineering C, 2015
Integrative approach in prevention and therapy of basal cellular carcinoma by association of three actives loaded into lipid nanocarriers
Gabriela Badea, Ioana Lacatusu, Cristina Ott, Nicoleta Badea, Iulia Grafu, et al.
Journal of Photochemistry and Photobiology B Biology, 2015
New approach to prepare willow bark extract-lipid based nanosystems with enhanced antioxidant activity
Elena Mitrea, Ioana Lacatusu, Nicoleta Badea, Cristina Ott, Ovidiu Oprea, et al.
Journal of Nanoscience and Nanotechnology, 2015
Use of various vegetable oils in designing photoprotective nanostructured formulations for UV protection and antioxidant activity
Gabriela Badea, Ioana Lăcătuşu, Nicoleta Badea, Cristina Ott, Aurelia Meghea
Industrial Crops and Products, 2015
Lipid nanocarriers based on natural compounds: An evolving role in plant extract delivery
Ioana Lacatusu, Nicoleta Badea, Gabriela Niculae, Natalita Bordei, Raluca Stan, et al.
European Journal of Lipid Science and Technology, 2014
Design of soft lipid nanocarriers based on bioactive vegetable oils with multiple health benefits
Ioana Lacatusu, Gabriela Niculae, Nicoleta Badea, Raluca Stan, Ovidiu Popa, et al.
Chemical Engineering Journal, 2014
Green silver nanobioarchitectures with amplified antioxidant and antimicrobial properties
Marcela Elisabeta Barbinta-Patrascu, Camelia Ungureanu, Stefan Marian Iordache, Ioana Raluca Bunghez, Nicoleta Badea, et al.
Journal of Materials Chemistry B, 2014
Eco-designed biohybrids based on liposomes, mint-nanosilver and carbon nanotubes for antioxidant and antimicrobial coating
Marcela Elisabeta Barbinta-Patrascu, Camelia Ungureanu, Stefan Marian Iordache, Ana Maria Iordache, Ioana-Raluca Bunghez, et al.
Materials Science and Engineering C, 2014
Nanobioarchitectures based on chlorophyll photopigment, artificial lipid bilayers and carbon nanotubes
Marcela Elisabeta Barbinta-Patrascu, Stefan Marian Iordache, Ana Maria Iordache, Nicoleta Badea, Camelia Ungureanu
Beilstein Journal of Nanotechnology, 2014
Influence of vegetable oil on the synthesis of bioactive nanocarriers with broad spectrum photoprotection
Gabriela Niculae, Ioana Lacatusu, Nicoleta Badea, Aurelia Meghea, Raluca Stan
Central European Journal of Chemistry, 2014
Rice bran and raspberry seed oil-based nanocarriers with self-antioxidative properties as safe photoprotective formulations
Gabriela Niculae, Ioana Lacatusu, Nicoleta Badea, Raluca Stan, Bogdan Stefan Vasile, et al.
Photochemical and Photobiological Sciences, 2014
Optimization of lipid nanoparticles composition for sunscreen encapsulation
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2013
Coencapsulation of butyl-methoxydibenzoylmethane and octocrylene into lipid nanocarriers: UV performance, photostability and in vitro release
Gabriela Niculae, Nicoleta Badea, Aurelia Meghea, Ovidiu Oprea, Ioana Lacatusu
Photochemistry and Photobiology, 2013
Lipid nanoparticles based on omega-3 fatty acids as effective carriers for lutein delivery. Preparation and in vitro characterization studies
Ioana Lacatusu, Elena Mitrea, Nicoleta Badea, Raluca Stan, Ovidiu Oprea, et al.
Journal of Functional Foods, 2013
Antioxidant properties of biohybrids based on liposomes and sage silver nanoparticles
Marcela Elisabeta Barbinta-Patrascu, Ioana-Raluca Bunghez, Stefan Marian Iordache, Nicoleta Badea, Radu-Claudiu Fierascu, et al.
Journal of Nanoscience and Nanotechnology, 2013
Forensic discrimination of ballpoint pen inks based on correlation of data obtained by optical and spectral methods
Revista De Chimie, 2013
Oxidative stress studies on plant DNA exposed to ozone
Journal of Optoelectronics and Advanced Materials, 2013
Antioxidant activity of solid lipid nanoparticles loaded with umbelliferone
I. Lacatusu, N. Badea, A. Murariu, O. Oprea, D. Bojin, et al.
Soft Materials, 2013
Physicochemical and microbiological characterisation of municipal sludge from romanian black sea coast wastewater treatment plants
Journal of Environmental Protection and Ecology, 2012
Novel bio-active lipid nanocarriers for the stabilization and sustained release of sitosterol
I Lacatusu, N Badea, R Stan, A Meghea
Nanotechnology, 2012
Nanoencapsulation of natural productswith multifunctional properties in silicaand hybrid organic - silica host matrices
Natural Products Structure Bioactivity and Applications, 2012
The effect of laurel and thymbra essential oils on antioxidant and antimicrobial properties of collagen hydrolysate
Romanian Biotechnological Letters, 2012
Lipid nanoparticles based on butyl-methoxydibenzoylmethane: In vitro UVA blocking effect
G Niculae, I Lacatusu, N Badea, A Meghea
Nanotechnology, 2012
Highly antioxidant carotene-lipid nanocarriers: Synthesis and antibacterial activity
Ioana Lacatusu, Nicoleta Badea, Oprea Ovidiu, Dionezie Bojin, Aurelia Meghea
Journal of Nanoparticle Research, 2012
Antioxidant properties of fungal biomaterial
Nicoleta Radu, Maria Nicoleta Badea, Mariana Ferdes, Ileana Rau
Molecular Crystals and Liquid Crystals, 2012
Cryoprotector effect on main properties of lipid nanoparticles loaded with bio-active compounds
Journal of Optoelectronics and Advanced Materials, 2012
Antioxidant silver nanoparticles green synthesized using ornamental plants
Journal of Optoelectronics and Advanced Materials, 2012
The influence of POSS substituent on synthesis and properties of hybrid materials based on urethane dimethacrylate (UDMA) and various polyhedral oligomeric silsesquioxane (POSS)
A. Lungu, N. M. Şulcă, E. Vasile, N. Badea, C. Pârvu, et al.
Journal of Applied Polymer Science, 2011
Nanostructures with liposomes and carbon nanotubese
Journal of Optoelectronics and Advanced Materials, 2011
Effect of vanadium on new silsesquioxane-nano silica encapsulated bio-active compounds with potential for bio-medical application
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2011
Vegetal nanoclusters in hybrid silica films prepared by sol-gel spin coating technique
I. Lacatusu, N. Badea, A. Murariu, C. Pirvu, A. Meghea
Journal of Non Crystalline Solids, 2011
Nanoencapsulation of natural products with multifunctional properties in silica and hybrid organic-silica host matrices
Biocompatible Nanomaterials Synthesis Characterization and Applications, 2011
The encapsulation effect of uv molecular absorbers into biocompatible lipid nanoparticles
Ioana Lacatusu, Nicoleta Badea, Alina Murariu, Aurelia Meghea
Nanoscale Research Letters, 2011
From nanoscale engineering to biomedical application - characterization of pulse electrodeposited biomimetic antibacterial coating on Ti6Al4Zr
Digest Journal of Nanomaterials and Biostructures, 2011
Effect of UV sunscreens loaded in solid lipid nanoparticles: A combinated SPF assay and photostability
Ioana Lacatusu, Nicoleta Badea, Alina Murariu, Dionezie Bojin, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2010
Silica polymeric networks templated with D-fructose - As host matrices for natural extracts immobilization
Ioana Lacatusu, Nicoleta Badea, Dionezie Bojin, Ion Iosub, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2010
Antioxidant capacity of lipid nanoparticles loaded with rosemary extract
I. Lacatusu, N. Badea, A. Murariu, C. Nichita, D. Bojin, et al.
Molecular Crystals and Liquid Crystals, 2010
Encapsulation of fluorescence vegetable extracts within a templated sol-gel matrix
Ioana Lacatusu, Nicoleta Badea, Rodica Nita, Alina Murariu, Florin Miculescu, et al.
Optical Materials, 2010
Correlation between antioxidant activity and hepatoprotective effect of a vegetal bioproduct
Cornelia Nichita, Georgeta Neagu, Virginia Vulturescu, Radu Albulescu, Viorel Vulturescu, et al.
Molecular Crystals and Liquid Crystals, 2010
Synthesis of high fluorescent silica hybrid materials by immobilization of orange peel extract in silica-silsesquioxane matrix
I. Lacatusu, N. Badea, R. Nita, M. Giurginca, D. Bojin, et al.
Journal of Physical Organic Chemistry, 2009
Role of silsesquioxane compounds used as 'building blocks' in sol-gel nanoencapsulation of retinyl palmitate
I. Lacatusu, R. Nita, N. Badea, D. Bojin, A. Meghea
Materials Research Innovations, 2009
Vegetal bioproducts with antioxidant activity for prophylactic and therapeutic effect
C. Nichita, G. Caraene, N. Badea, M. Giurginca, C. Vaca-Garcia, et al.
Materials Research Innovations, 2009
Novel fluorescence nanostructured materials obtained by entrapment of an ornamental bush extract in hybrid silica glass
Ioana Lacatusu, Nicoleta Badea, Dionezie Bojin, Silvia Iosub, Aurelia Meghea
Journal of Sol Gel Science and Technology, 2009
Effect of surfactants on stability of colloidal sols as precursors in sol-gel encapsulation
Ioana Lacatusu, Nicoleta Maria Badea, Aurelia Meghea
Key Engineering Materials, 2009
Photo-oxidative stress on model membranes - Studies by optical methods
Marcela Elisabeta Bărbînţă Pătraşcu, Nicoleta Maria Badea, Laura Ţugulea, Aurelia Meghea
Key Engineering Materials, 2009
Synthesis and characterization of potentially antimicrobial complexes of Zn(II) and Cu(II) with chlorhexidine as ligand
Florina Dumitru, Maria Giurginca, O. Micu, C. Guran, Anca Razvan, et al.
Key Engineering Materials, 2009
Evaluation of scavenger properties of some flavonoidic vegetal extracts obtained from crataegus monogyna jacq
Cornelia Nichita, Georgeta Neagu, Virginia Vulturescu, Lucia Pirvu, Nicoleta Maria Badea, et al.
Key Engineering Materials, 2009
The protection effects of lipid extracts from Mytilus galloprovincialis Lmk., Rapana venosa, Trygon pastinaca and Squalus achantias evaluated by in vitro UVA radiation and SPF analysis in sun burns
Archives of the Balkan Medical Union, 2008
Complex effects of sunscreen agents and flavonoid antioxidants devoted to enhance photoprotection of dermal tissues
Nicoleta Badea, Maria Giurginca, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2008
Preliminary results for DNA-surfactant Ni(II) complex structures inclusions into hybrid organic-inorganic nano-composites
Rodica-Mirela Nita, Nicoleta Badea, Laura Bancu, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2008
Enhanced fluorescence of Ni(II) complex compounds in the presence of DNA components
Laura Bancu, Nicoleta Badea, Rodica Nita, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2008
Oxidative stress simulation on chlorophyll a lipid model membranes - Chemiluminescent Studies
Revista De Chimie, 2008
Study of deterioration of historical parchments by various thermal analysis techniques complemented by SEM, FTIR, UV-Vis-NIR and unilateral NMR investigations
Elena Badea, Lucreţia Miu, P. Budrugeac, Maria Giurginca, A. Mašić, et al.
Journal of Thermal Analysis and Calorimetry, 2008
Characterization of aluminophosphate glasses containing Pr3+, Er3+, Gd3+ and Yb3+ ions
Advanced Materials Research, 2008
Optical characterization of the phosphate glasses containing pair transition ions
M. Elisa, Cristiana Grigorescu, Ileana Vasiliu, M. Bulinski, V. Kuncser, et al.
Optical and Quantum Electronics, 2007
Evaluating titanium alloys bioactivity in terms of hydroxyapatite (HA) forming capability
Revista De Chimie, 2007
Skin protective materials for human operators working in industrial environment
Aurelia Meghea, C. Borlescu, N. Badea, I. Demetrescu
Ifmbe Proceedings, 2007
Spectral technics for identifying tanning agents in the heritage leather items
Revista De Chimie, 2007
The behavior of SiC films fabricated by hybrid laser- magnetron deposition after immersion
Nicoleta Badea, M. Jelinek, T. Tite, Mariana Prodana, A. Campean, et al.
Key Engineering Materials, 2007
The synthesis of nanocrystaline electroluminescent chalcogenides
Journal of Optoelectronics and Advanced Materials, 2007
Natural antioxidants for thermo-oxidative stabilization of elastomers
Revue Roumaine De Chimie, 2006
Redox properties of some aminoacids and proteins
Ion Iosub, Maria Giurginca, Nicoleta Iftimie, Aurelia Meghea
Molecular Crystals and Liquid Crystals, 2006
New nanostructured complex systems with antioxidant and photoprotective activity
Aurelia Meghea, Nicoleta Iftimie, Maria Giurginca, Elena Cremenescu, Viorica Trandafir
Molecular Crystals and Liquid Crystals, 2006
NIR study of chemically modified cellulosic biopolymers
J. Peydecastaing, J. Bras, C. Vaca-Garcia, M. E. Borredon, Nicoleta Iftimie, et al.
Molecular Crystals and Liquid Crystals, 2006
Optical and structural investigation on rare-earth-doped aluminophosphate glasses
M. Elisa, I. Cristina Vasiliu, Cristiana E.A. Grigorescu, Bogdan Grigoras, Horatiu Niciu, et al.
Optical Materials, 2006
Advanced techniques for quantification of antioxidant effects in fluid nanostructured systems obtained from natural oils
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2005
Spectral methods for evaluation of photoprotective and antioxidant activities in nanostructurated complexes based on collagen and plant extracts
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2005
Optical and electronic properties of the aluminophosphate glasses doped with 3d-transition metal ions
Reviews on Advanced Materials Science, 2005
Influence of some therapeutically active biguanides and their metal complexes on the antioxidant activity
Revue Roumaine De Chimie, 2005
Comportarea aliajelor de Ti6Al4V în electroliţi care simuleazǎ biolichide specifice în cavitatea bucalǎ
Revista De Chimie, 2005
Principii metodologice pentru evaluarea obiectelor de patrimoniu din piele şi pergament (I)
Revista De Chimie, 2005
Depistarea falsurilor din cafea prin metode spectrale
Revista De Chimie, 2005
CdSSe doped aluminophosphate glasses obtained by a wet method
Physics and Chemistry of Glasses, 2005
Kinetic characteristics of destruction process of elastomers protected by quinoneimines
Materiale Plastice, 2004
Chemiluminescence characteristics of products resulted after degradation of some fatty acids
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2004
The evaluation of the oxidative stress in biosystems. II. The effects of ozone, UV irradiation and peroxidation
Revista De Chimie, 2004
The evaluation of the oxidative stress in biosystems. IV. Complex biological structures
Revista De Chimie, 2004
Protection of vulcanizates by synergistic systems of antidegradants
Materiale Plastice, 2004
The Estimation of the Antioxidant Effect of Plants Extracts by Chemiluminescence
Revista De Chimie, 2004
The quantification of the oxidative stress in biosystems. III. The behaviour during peroxidation and UV irradiation of some vitamins
Revista De Chimie, 2004
Chemiluminescence technique for the evaluation of thermooxidative stability of some mineral and vegetable oils protected by antioxidants
Revista De Chimie, 2004
Behaviour to accelerate ageing of some natural biopolymer constituents of parchment
Aurelia Meghea, Maria Giurginca, Nicoleta Iftimie, Lucreţia Miu, Bocu Viorica, et al.
Molecular Crystals and Liquid Crystals, 2004
Rubber protection by synergistic systems consisting of aromatic diamines and quinonediimines
UPB Scientific Bulletin Series B Chemistry and Materials Science, 2003
Complexes with mixed (OO) and (ONO) donor groups. I. Synthesis and characterization of Ni(II), Pt(II), Cu(II), VO(IV) new complexes with 1-phenyl-3-methyl-4-azo-(2-carboxy-phenyl)-pyrazol-5-one and alylacetoacetate as ligands
Revista De Chimie, 2003
Complexes with mixed (OO) and (ONO) donor groups. II. Synthesis and characterization of new complexes of VO(IV), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) with 1-phenyl-3-methyl-4-azo-(2′-carboxy-phenyl)-pyrazol-5-one, 1-(2′-benzthyazolyl )-3-methyl-4-azo-(4″-nitro-phenyl)-pyrazol-5-one and vynil alylacetoacetate as ligands
Revista De Chimie, 2003
Thermo-oxidative degradation of some elastomers with a high content of 3,4 isoprene units
G Ivan, Aurelia Meghea, Maria Giurginca, Nicoleta Iftimie
Polymer Degradation and Stability, 2003
Protection of rubber vulcanizates with couples of diamine antidegradants and selected additives
Materiale Plastice, 2003
Oxidative stress quantifying in biosystems. I. Chemiluminescence testing of the antioxidant activity of some molecules of biological interest
Revista De Chimie, 2003
The characterization of some quinones and their derivatives by spectroelectrochemistry and chemiluminescence in aprotic environment
Revista De Chimie, 2003
Studies on the photostoragechemiluminescence of aromatic ketones with reactive oxygen species. Prospects for analytical applications
K Papadopoulos, T Triantis, K Tsagaraki, D Dimotikali, N Iftimie, et al.
Journal of Photochemistry and Photobiology A Chemistry, 2002
The study of the electrochemical deposition of Prussian Blue onto platinum and optically transparent indium-tin oxide electrodes
Revista De Chimie, 2002

Badea Nicoleta

RESEARCH, TEACHING, or OTHER INTERESTS

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS