@rmlh.nic.in
Professor orthopaedic surgery
Atal Bihari Vajpayee Institute of Medical Sciences Dr. Ram Manohar Lohia Hospital, New Delhi, 110001, India
MBBS, MS
Orthopedics and Sports Medicine, Oncology
Scopus Publications
Vibhu Krishnan Viswanathan, Karthikeyan. P. Iyengar, and Vijay Kumar Jain
Elsevier BV
Raju Vaishya, Karthikeyan P. Iyengar, Mohit Kumar Patralekh, Rajesh Botchu, Kapil Shirodkar, Vijay Kumar Jain, Abhishek Vaish, and Marius M. Scarlat
Springer Science and Business Media LLC
Vibhu Krishnan Viswanathan, Mohit Kumar Patralekh, Guna Pratheep Kalanjiyam, Karthikeyan P. Iyengar, and Vijay Kumar Jain
Springer Science and Business Media LLC
Ravi Saini, Madhan Jeyaraman, Tarun Jayakumar, Karthikeyan P. Iyengar, Naveen Jeyaraman, and Vijay Kumar Jain
Springer Science and Business Media LLC
Karthik Vishwanathan, Vijay Kumar Jain, Mohit Kumar Patralekh, and Vibhu Krishnan Viswanathan
Elsevier BV
Raju Vaishya, Karthikeyan P. Iyengar, Vijay Kumar Jain, and Abhishek Vaish
Springer Science and Business Media LLC
Vibhu Krishnan Viswanathan, Vijay Kumar Jain, Chetan Sangani, Rajesh Botchu, Karthikeyan. P. Iyengar, and Raju Vaishya
Elsevier BV
H.B. Guruprasad, Mohit Singh, Anant kumar Naik, and Vijay Kumar Jain
Elsevier BV
Madhan Jeyaraman, Naveen Jeyaraman, Arulkumar Nallakumarasamy, Karthikeyan P Iyengar, Vijay Kumar Jain, Anish G Potty, and Ashim Gupta
Baishideng Publishing Group Inc.
The irrational and prolonged use of antibiotics in orthopaedic infections poses a major threat to the development of antimicrobial resistance. To combat antimicrobial resistance, researchers have implemented various novel and innovative modalities to curb infections. Nanotechnology involves doping ions/metals onto the scaffolds to reach the target site to eradicate the infective foci. In this connotation, we reviewed silver nanoparticle technology in terms of mechanism of action, clinical applications, toxicity, and regulatory guidelines to treat orthopaedic infections.
Mohit Singh, Madhan Jeyaraman, Naveen Jeyaraman, Tarun Jayakumar, Karthikeyan. P. Iyengar, and Vijay Kumar Jain
Elsevier BV
Ashim Gupta, Nicola Maffulli, and Vijay Kumar Jain
MDPI AG
The last decade has seen a noticeable upsurge in the use of biologics, including platelet-rich plasma (PRP), for applications in musculoskeletal regenerative medicine [...]
Vibhu Krishnan Viswanathan, Mohit Kumar Patralekh, Guna Pratheep Kalanjiyam, Karthikeyan P. Iyengar, Karthik Vishwanathan, and Vijay Kumar Jain
Springer Science and Business Media LLC
Vibhu Krishnan Viswanathan, Mohit Kumar Patralekh, Guna Pratheep Kalanjiyam, Karthikeyan P. Iyengar, Karthik Vishwanathan, and Vijay Kumar Jain
Springer Science and Business Media LLC
Madhan Jeyaraman, Abdus Sami, Arulkumar Nallakumarasamy, Naveen Jeyaraman, and Vijay Kumar Jain
Springer Science and Business Media LLC
Madhan Jeyaraman, Arulkumar Nallakumarasamy, and Vijay Kumar Jain
Elsevier BV
Madhan Jeyaraman, Vijay Kumar Jain, and Raju Vaishya
Elsevier BV
Benjamin Thomas Vincent Gowers, Michael Sean Greenhalgh, Kathryn Dyson, Karthikeyan P Iyengar, Vijay K Jain, and Riad F Adam
SAGE Publications
Background: Hip fractures are common presentations to orthopaedic departments, and their surgical management often results in blood transfusions. Compared with general anaesthesia, regional anaesthesia reduces the need for transfusions and mortality in the wider surgical population. Aims: In hip fracture patients, our primary outcome measure was to examine any relationship between anaesthetic modality and transfusion rates. The secondary outcome measure was to assess the relationship between anaesthetic modality and one-year mortality. Methods: A retrospective cohort study of 280 patients was carried out in 2017 and 2018. Data were collected from patient records, local transfusion laboratory and the national hip fracture database. Results: A total of 59.6% had regional and 40.4% general anaesthesia. Regional anaesthesia patients were younger with fewer comorbidities (p < .05). About 19.8% regional and 34.5% general anaesthesia patients received transfusions (odds ratio (OR) = 0.47, p < .05); 13.6% were taking anticoagulants and were less likely to receive a regional anaesthetic (31.6% versus 64%, OR = 0.26, p < .05). One-year mortality was 27% for regional and 37% for general anaesthetic patients (OR = 0.64, p = .09). Conclusion: Regional anaesthesia halved the risk of blood transfusion. Anticoagulated patients were 74% less likely to receive regional anaesthetics, but had no additional transfusion risk. With optimisation, a larger proportion of patients could have regional anaesthesia.
Karthikeyan P Iyengar, Aakaash S Venkatesan, Vijay K Jain, Madapura K Shashidhara, Husam Elbana, and Rajesh Botchu
Informa UK Limited
Abstract Polytrauma, a patient’s condition with multiple injuries that involve multiple organs or systems, is the leading cause of mortality in young adults. Trauma-related injuries are a major public health concern due to their associated morbidity, high disability, associated death, and socioeconomic consequences. Management of polytrauma patients has evolved over the last few decades due to the development of trauma systems, improved pre-hospital assessment, transport and in-hospital care supported by complementary investigations. Recognising the mortality patterns in trauma has led to significant changes in the approach to managing these patients. A structured approach with application of advanced trauma life support (ATLS) algorithms and optimisation of care based on clinical and physiological parameters has led to the development of early appropriate care (EAC) guidelines to treat these patients, with subsequent improved outcomes in such patients. The journey of a polytrauma patient through the stages of pre-hospital care, emergency resuscitation, in-hospital stabilization and rehabilitation pathway can be associated with risks at any of these phases. We describe the various risks that can be anticipated during the management of polytrauma patients at different stages and provide clinical insights into early recognition and effective treatment of these to improve clinical outcomes.
Karthikeyan P. Iyengar, Vijay Kumar Jain, Arulkumar Nallakumarasamy, and Madhan Jeyaraman
Springer Science and Business Media LLC
Gaurav Kumar Upadhyaya, Abdus Sami, Mohit Kumar Patralekh, Anil Agarwal, Karthikeyan P. Iyengar, Aayush Aryal, Pragya Bhagwati, Bhavuk Garg, and Vijay Kumar Jain
SAGE Publications
Study Design Systematic Review and Meta-analysis Objectives This systematic review and meta-analysis is aimed to assess effectiveness, safety, clinical, functional and radiological outcome of either combined anteroposterior or posterior-only approach in the surgical management of active tubercular disease of paediatric thoracolumbar spine. Methods A systematic literature search through PubMed, Scopus, Web of Science and Cochrane Library database was performed. Data extraction was undertaken following methodological quality assessment. Results 9 out of the 182 publications identified, were included for analysis. A total of 247 patients were analysed. Two amongst the 9 studies were retrospective comparative studies evaluating posterior approach with combined anteroposterior approach and were considered for comparative meta-analysis. Blood loss and duration of surgery was significantly higher in the anteroposterior group, as compared to the posterior-only group. There was no significant difference between the 2 groups in terms of post-operative kyphosis angles, final kyphosis angles, number of complications, functional outcome and spinal fusion time. However, all the included studies were non-randomised and retrospective. Only 2 of them had a control group with a high heterogeneity amongst these 2 studies. Conclusion The inference from the studies included in this review suggests that equivalent results can be achieved with posterior-only approach for thoracolumbar tuberculosis in children as compared to anteroposterior approach, with much lower complexity, reduced blood loss and shorter surgical time. However, due to the high risk of bias and considerable heterogeneity among the studies included, we cannot conclude whether one approach is better than the other.
Madhan Jeyaraman, Vijay Kumar Jain, and Karthikeyan P. Iyengar
Elsevier BV
Neha Singh, Prajwala Gupta, Sunayana Misra, Arvind Ahuja, and Vijay Kumar Jain
Wiley
Alveolar soft part sarcoma (ASPS) is a rarely diagnosed tumour of deep soft tissue origin. This tumour is more common in adolescents and young adults and has a slowly progressive clinical course, which often leads to delayed diagnosis and treatment. It is highly vascular, can be confused with other entities like haemangiomas and arteriovenous malformations clinically and radiologically and is thus challenging to report on fine needle aspiration cytology (FNAC). Diagnosing the tumour is difficult on cytology, so knowledge of this entity and the differentials with its morphological mimics on cytology is required for timely diagnosis and early management of the patient. We report a case of ASPS in a young female who presented with a large, painless swelling in the thigh, diagnosed on cytology combined with ancillary testing with immunohistochemical markers.
Ahmed Saad, Mohit Kumar Patralekh, Vijay Kumar Jain, Sagaurav Shrestha, Rajesh Botchu, and Karthikeyan. P. Iyengar
Elsevier BV
Karthikeyan.P. Iyengar, Vijay Kumar Jain, and Raju Vaishya
Elsevier BV
Karthikeyan P. Iyengar, Eindere Zaw Pe, Janaranjan Jalli, Madapura K. Shashidhara, Vijay K. Jain, Abhishek Vaish, and Raju Vaishya
Elsevier BV