Pharmacology, Toxicology and Pharmaceutics, Pharmaceutical Science, Drug Discovery, General Pharmacology, Toxicology and Pharmaceutics
7
Scopus Publications
74
Scholar Citations
5
Scholar h-index
2
Scholar i10-index
Scopus Publications
Accounts on the nano-carrier system for diagnosis purposes Therapeutic Nanocarriers in Cancer Treatment Challenges and Future Perspective, 2023
Lipoidal Carrier as Drug Delivery System Nanoparticles and Nanocarriers Based Pharmaceutical Freparations, 2022
Polymeric Nanoparticles as Drug Delivery System: Basic Concepts and Applications Nanoparticles and Nanocarriers Based Pharmaceutical Freparations, 2022
Nanocarriers For Drug Targeting Nanoparticles and Nanocarriers Based Pharmaceutical Freparations, 2022
In-vitro evaluation of nano-liposomal formulation of fluconazole and amphotericin b against visceral leishmaniasis Atul Tripathi, Amber Vyas Research Journal of Pharmacy and Technology, 2021 Objectives: The aim of the present study was to compare the efficacy of a dual and single drug loaded nano-liposomal formulation of Amphotericin B and Fluconazole for the treatment of visceral leishmaniasis with plain drugs. Methods: We have formulated nano-liposomes (200-250 nm) from Amphotericin B and Fluconazole using dry film hydration method and have tested their efficacy on promastigotes and amastigotes of Leishmania donovani strain. Physicochemical characterization, entrapment study, stability study, in-vitro release study, in-vitro macrophagic uptake studies (Confocal microscopy) and in-vitro antileishmanial activity were evaluated for various formulations containing Amphotericin B and Fluconazole. Results: The in-vitro cellular uptake confocal studies revealed that NR-loaded AmpB + Flu nanoliposomes have enhanced cellular uptake of formulation. The in-vitro inhibition of promastigotes and amastigotes with liposome containing both Amphotericin B and Fluconazole was significantly more than with liposomes containing individual drugs. The IC50 and CC50 of AmpB + Flu nanoliposomes against promastigotes was found to be 3.308μg/mL and 73.48μg/mL respectively, while the IC50 against axenic and intramacrophagic amastigotes was found to be 3.412 and 3.7028μg/mL respectively. Conclusion: In conclusion, Liposomal formulation containing both Amphotericin B and Fluconazole had significantly greater efficacy than conventional combination and other formulation with individual drugs. Current dual drug loaded formulation may have a favourable safety profile, and if production costs are low, it may prove to be a feasible alternative to currently available therapy after in-vivo testing.
In Vitro Antioxidant and Anthelmintic Activity on Luffa cylindrica Leaf Extracts Atul Tripathi, Manisha Tandon, Amol Chandekar, Nilam Soni, Neeraj Upmanyu Journal of Herbs Spices and Medicinal Plants, 2016 The antioxidant and anthelmintic activities of Luffa cylindrica leaf extracts in ethanol, methanol, and chloroform were investigated. The antioxidant activity was determined by 2,2-diphenyl-picrylhydrazyl (DPPH) and superoxide scavenging assay; the anthelmintic activity was tested against the Indian earthworm (Pheretima posthuma). The methanolic and chloroform leaf extracts showed in vitro antioxidant activity comparable to the standard antioxidant (ascorbic acid); the anthelmintic activities of the ethanolic extract was comparable with the standard drug mebendazole.
Significance of jobs plot in cyclodextrin complexation Amber Vyas, Bina Gidwani, Atul Tripathi, Preeti Dhruve Research Journal of Pharmacy and Technology, 2016 Jobs plot or continuous variation method is used to estimate the stoichiometry in cyclodextrin complexation. Cyclodextrin complexation is well known as widely acceptable technique for improving the poor physicchemical properties of BCS class II and class IV drugs. The stoichiometry of the inclusion complex is given by the number of guest and host molecules present in the supramolecular complex/inclusion system. The most common stoichiometry is 1: 1, implying the inclusion of a single guest molecule. Now-a-days jobs plot is replaced by phase-solubility study. Jobs plot deals with spectral methods mainly for molecular modelling study of drugs and bioactives.
RECENT SCHOLAR PUBLICATIONS
In-Vivo Anti-diabetic activity of Leonotis nepetaefolia (L.) R. Br. Root in Alloxan induced Diabetic Model S Dwivedi, A Chandekar, A Tripathi, R Mishra, M Chhajed, K Sharma, ... NATURALISTA CAMPANO 28 (1), 2190-2193 , 2024 2024.0 Citations: 5
Lipoidal Carrier as Drug Delivery System B Gidwani, P Namdeo, S Tiwari, A Tripathi, RK Pandey, SS Shukla, ... Nanoparticles and Nanocarriers Based Pharmaceutical Formulations, 273 , 2022 2022.0
Nanoparticles and Nanocarriers Based Pharmaceutical Formulations AK Jain, K Mishra Bentham Science Publishers , 2022 2022.0 Citations: 3
Nanocarriers For Drug Targeting B Gidwani, V Sahu, P Namdeo, S Tiwari, A Tripathi, RK Pandey, ... Nanoparticles and Nanocarriers Based Pharmaceutical Formulations, 93 , 2022 2022.0
Polymeric Nanoparticles as Drug Delivery System: Basic Concepts and Applications S Tiwari, B Gidwani, P Namdeo, A Tripathi, RK Pandey, SS Shukla, ... Nanoparticles and Nanocarriers Based Pharmaceutical Preparations, 26-54 , 2022 2022.0 Citations: 2
In-vitro evaluation of nano-liposomal formulation of Fluconazole and Amphotericin B against visceral leishmaniasis A Tripathi, A Vyas Research Journal of Pharmacy and Technology 14 (9), 4929-4933 , 2021 2021.0 Citations: 2
In vitro and in vivo antileishmanial activity of parthenin a sesquiterpene lactone obtained from Parthenium hysterophorous A Tripathi, R Kumar, G Sahoo, A Vyas, H Kumar, M Kumar, P Das International Journal of Infectious Diseases 73, 302 , 2018 2018.0 Citations: 1
A review on Clitoria ternatea (Linn.): Chemistry and pharmacology NK Singh, JK Gupta, K Shah, PM Mishra, A Tripathi, NS Chauhan, ... Medicinal Plants and its Therapeutic Uses 1, 1-17 , 2017 2017.0 Citations: 20
In vitro evaluation of Transdermal Patch of Palonosetron for Antiemetic Therapy A Tripathi, P Tyagi, A Vyas, B Gidwani, A Chandekar, H Sharma, ... Int J of Drug Deliv 9 (4), 119-124 , 2017 2017.0 Citations: 3
Evaluation of hepatoprotective effect of Waltheria indica against various NSAIDs-induced hepatic damage in rats A Chandekar, N Upamanyu, A Vyas, A Tripathi, S Agrawal, D Jhade International Journal of Phytomedicine 9 (1), 157-166 , 2017 2017.0 Citations: 4
Preliminary Screening of Waltheria indica (L.) Plant for Its Anti-Inflammatory Activity A Chandekar, A Vyas, N Upmanyu, A Tripathi, S Agrawal Int. J. Phytomed 9, 275-278 , 2017 2017.0 Citations: 6
Antioxidant and antiulcer potential on leaves of Brassica nigra L. against gastric ulcer A Tripathi, R Punekar, V Jain, CK Tyagi, A Chandekar, A Vyas International Journal of Phytomedicine 9, 144-150 , 2017 2017.0 Citations: 2
In Vitro Antioxidant and Anthelmintic Activity on Luffa cylindrica Leaf Extracts NSNU Atul Tripathi, Manisha Tandon, Amol Chandekar Journal of Herbs, Spices & Medicinal Plants 22 (4), 348-355 , 2016 2016.0 Citations: 15
In-vivo Diuretic and Antiulcer Activity on Flowers of Sphaeranthus indicus Linn. A Tripathi, A Vyas Journal of Ravishankar University, Part-B Science 29 , 2016 2016.0 Citations: 1
Significance of Jobs Plot in Cyclodextrin Complexation A Vyas, B Gidwani, A Tripathi, P Dhruve Research Journal of Pharmacy and Technology 9 (7), 1013-1016 , 2016 2016.0 Citations: 3
In-vitro Anti-arthritic and Anti-platelet Activity of Galinsoga parviflora Linn M Singh, AK Singh, Y Shivhare, A Tripathi, N Upmanyu Journal of Novel Research in Pharmacy & Technology, 13-14 , 2014 2014.0 Citations: 5
Estimation of Levocetrizine UV/Vis spectroscopic method in tablet dosage from A Tripathi, P Ghode, H Dhongade, S Nayak The Pharmacist 2 (2), 33-35 , 2007 2007.0 Citations: 2
In-Vivo Anti-diabetic activity of Leonotis nepetaefolia (L.) R. Br. Root in Alloxan induced Diabetic Model S Dwivedi, A Chandekar, A Tripathi, R Mishra, M Chhajed, PK Sharma, ...
MOST CITED SCHOLAR PUBLICATIONS
A review on Clitoria ternatea (Linn.): Chemistry and pharmacology NK Singh, JK Gupta, K Shah, PM Mishra, A Tripathi, NS Chauhan, ... Medicinal Plants and its Therapeutic Uses 1, 1-17 , 2017 2017.0 Citations: 20
In Vitro Antioxidant and Anthelmintic Activity on Luffa cylindrica Leaf Extracts NSNU Atul Tripathi, Manisha Tandon, Amol Chandekar Journal of Herbs, Spices & Medicinal Plants 22 (4), 348-355 , 2016 2016.0 Citations: 15
Preliminary Screening of Waltheria indica (L.) Plant for Its Anti-Inflammatory Activity A Chandekar, A Vyas, N Upmanyu, A Tripathi, S Agrawal Int. J. Phytomed 9, 275-278 , 2017 2017.0 Citations: 6
In-Vivo Anti-diabetic activity of Leonotis nepetaefolia (L.) R. Br. Root in Alloxan induced Diabetic Model S Dwivedi, A Chandekar, A Tripathi, R Mishra, M Chhajed, K Sharma, ... NATURALISTA CAMPANO 28 (1), 2190-2193 , 2024 2024.0 Citations: 5
In-vitro Anti-arthritic and Anti-platelet Activity of Galinsoga parviflora Linn M Singh, AK Singh, Y Shivhare, A Tripathi, N Upmanyu Journal of Novel Research in Pharmacy & Technology, 13-14 , 2014 2014.0 Citations: 5
Evaluation of hepatoprotective effect of Waltheria indica against various NSAIDs-induced hepatic damage in rats A Chandekar, N Upamanyu, A Vyas, A Tripathi, S Agrawal, D Jhade International Journal of Phytomedicine 9 (1), 157-166 , 2017 2017.0 Citations: 4
Nanoparticles and Nanocarriers Based Pharmaceutical Formulations AK Jain, K Mishra Bentham Science Publishers , 2022 2022.0 Citations: 3
In vitro evaluation of Transdermal Patch of Palonosetron for Antiemetic Therapy A Tripathi, P Tyagi, A Vyas, B Gidwani, A Chandekar, H Sharma, ... Int J of Drug Deliv 9 (4), 119-124 , 2017 2017.0 Citations: 3
Significance of Jobs Plot in Cyclodextrin Complexation A Vyas, B Gidwani, A Tripathi, P Dhruve Research Journal of Pharmacy and Technology 9 (7), 1013-1016 , 2016 2016.0 Citations: 3
Polymeric Nanoparticles as Drug Delivery System: Basic Concepts and Applications S Tiwari, B Gidwani, P Namdeo, A Tripathi, RK Pandey, SS Shukla, ... Nanoparticles and Nanocarriers Based Pharmaceutical Preparations, 26-54 , 2022 2022.0 Citations: 2
In-vitro evaluation of nano-liposomal formulation of Fluconazole and Amphotericin B against visceral leishmaniasis A Tripathi, A Vyas Research Journal of Pharmacy and Technology 14 (9), 4929-4933 , 2021 2021.0 Citations: 2
Antioxidant and antiulcer potential on leaves of Brassica nigra L. against gastric ulcer A Tripathi, R Punekar, V Jain, CK Tyagi, A Chandekar, A Vyas International Journal of Phytomedicine 9, 144-150 , 2017 2017.0 Citations: 2
Estimation of Levocetrizine UV/Vis spectroscopic method in tablet dosage from A Tripathi, P Ghode, H Dhongade, S Nayak The Pharmacist 2 (2), 33-35 , 2007 2007.0 Citations: 2
In vitro and in vivo antileishmanial activity of parthenin a sesquiterpene lactone obtained from Parthenium hysterophorous A Tripathi, R Kumar, G Sahoo, A Vyas, H Kumar, M Kumar, P Das International Journal of Infectious Diseases 73, 302 , 2018 2018.0 Citations: 1
In-vivo Diuretic and Antiulcer Activity on Flowers of Sphaeranthus indicus Linn. A Tripathi, A Vyas Journal of Ravishankar University, Part-B Science 29 , 2016 2016.0 Citations: 1
Lipoidal Carrier as Drug Delivery System B Gidwani, P Namdeo, S Tiwari, A Tripathi, RK Pandey, SS Shukla, ... Nanoparticles and Nanocarriers Based Pharmaceutical Formulations, 273 , 2022 2022.0
Nanocarriers For Drug Targeting B Gidwani, V Sahu, P Namdeo, S Tiwari, A Tripathi, RK Pandey, ... Nanoparticles and Nanocarriers Based Pharmaceutical Formulations, 93 , 2022 2022.0
In-Vivo Anti-diabetic activity of Leonotis nepetaefolia (L.) R. Br. Root in Alloxan induced Diabetic Model S Dwivedi, A Chandekar, A Tripathi, R Mishra, M Chhajed, PK Sharma, ...
