HONO, a key sink of isoprene-derived Criegee intermediates (MACR-oxide and MVK-oxide) Vishva Jeet Anand, Pradeep Kumar Physical Chemistry Chemical Physics, 2026 We investigated the reactions of biogenic (methyl vinyl ketone oxide and methacrolein oxide) and anthropogenic (acetaldehyde oxide) Criegee intermediates with nitrous acid (HONO) using quantum chemical calculations and kinetic modelling.
H5IO6, as an Efficient Reagent for the Aromatization of Tetrahydro-β-carbolines: Total Synthesis of Norharman, Harmane, Harmine, Kumujian-C, and Orthoscuticellines B Jagjivan K. Sabane, Sunil V. Gaikwad, Jayant M. Gajbhiye, Pradeep Kumar Chemistryselect, 2026 A new method is reported for the synthesis of β ‐carbolines and their derivatives using H 5 IO 6 in DMSO solvent. The method is mild and efficient for oxidative decarboxylation and aromatization of tetrahydro β ‐carbolines (TH β C), resulting in good to excellent yields (70% to 88%) of β ‐carbolines. This protocol has further been utilized for the synthesis of β ‐carbolines based natural products, for examples, norharmane, harmane, harmine, Kumujian‐C, and Orthoscuticellines A and B.