Sahar Younes Ibrahim Issa

@linkedin.com

Department of Clinical Toxicology, Forensic Medicine & Medical Ethics, Faculty of Medicine, Alexandria University, Egypt
Professor of Forensic Medicine, Clinical Toxicology & Medical Ethics

Sahar Younes Ibrahim Issa
Dr. Issa's research work exceeded 35 publications in both National & International Journals. She is interested in many areas of research focused on Drug Poisoning, Substances of Abuse, Designer Drugs, Forensic Toxicology, Electronic Health in Fields of Toxicology & Forensic Medicine, besides studying Systemic effects of acute toxicity related to drugs, herbs, Pesticides, and food.
Dr. Sahar presented oral talks and Poster presentations in many National and International Toxicology and Forensic sciences conferences and meetings. She is highly interested in investigating heavy metal poisonings, with interests in Lead Toxicity. She has been an She has been an Editorial board member and reviewer in many reputable medical National & International Journals in clinical, analytical, experimental toxicology, and forensic medicine.
She has a long expertise in Toxicology and forensic medicine fields exceeding 25 years in educational and governmental bodies inside & outside Egypt.

EDUCATION

Dr. Sahar Issa got her MSc (2001) and doctorate degrees (2009) in Clinical Toxicology and Forensic Medicine from Alexandria University-Egypt.
Her research work exceeded 35 publications in both National & International Journals. She is interested in many areas of research focused on Drug Poisoning, Substances of Abuse, Designer Drugs, Forensic Toxicology, Electronic Health in Fields of Toxicology & Forensic Medicine, besides studying Systemic effects of acute toxicity related to drugs, herbs, Pesticides, and food.
Dr. Sahar presented oral talks and Poster presentations in many National and International Toxicology and Forensic sciences conferences and meetings. She is highly interested in investigating heavy metal poisonings, with interests in Lead Toxicity.

RESEARCH, TEACHING, or OTHER INTERESTS

Medicine, Toxicology, Pathology and Forensic Medicine, Pharmacology, Toxicology and Pharmaceutics
19

Scopus Publications

Scopus Publications

  • Post-infarction cardiac tamponade causing sudden death: an autopsy series highlighting right ventricular free-wall rupture
    Sahar Issa, Ghadeer M. M. Abdelaal, Dalia AlSaif, Omar Ba Adheem, Zainab Al-Ruwai, et al.
    Egyptian Journal of Forensic Sciences, 2026
    Background Cardiac tamponade is a rapidly fatal condition caused by the accumulation of fluid or blood within the pericardial sac, resulting in impaired cardiac filling and hemodynamic collapse. Myocardial rupture following acute myocardial infarction (MI) is a rare but catastrophic cause of sudden cardiac death and is often diagnosed only at autopsy. Case presentations Three cases of sudden death due to cardiac tamponade secondary to myocardial rupture were examined. Autopsy revealed hemopericardium associated with ventricular free-wall rupture in the setting of recent transmural MI. Although left ventricular rupture was the predominant finding, one case showed the uncommon occurrence of right ventricular free-wall rupture. Histopathological examination confirmed the timing and extent of infarction in all cases. Conclusion These cases highlight myocardial rupture as a critical and often fatal complication of acute MI. Careful postmortem examination, including detailed assessment of both ventricles and histopathological analysis, is essential for accurate diagnosis. Recognition of this complication has important implications for both forensic practice and clinical awareness.
  • Electrocution-related fatalities in Eastern Province of Saudi Arabia: a 24-year retrospective autopsy study
    Marwa Al Bayat, Omar Baadheem, Abdul Rahman Al Zahrani, Majdi Al Rabiea, Abdul Salam Al Ruwaili, et al.
    Egyptian Journal of Forensic Sciences, 2025
    Background Fatal injuries caused by electrocution have been documented worldwide, but detailed studies focusing on their patterns and demographic distribution in Saudi Arabia are limited. This study investigates the characteristics and forensic findings of electrocution-related deaths in the Eastern Region, Saudi Arabia, over two decades. The study analyzed 73 cases of electrocution-related deaths reported to the Forensic Medicine Department in the Eastern Region, Saudi Arabia, from 2000 to 2023. Data on demographic, occupational, autopsy, and histopathological findings were collected and evaluated. Results Most victims were non-Saudi nationals (78.1%), with males constituting 95.8% of the cases. The age groups most affected were 31–40 years (34.25%) and 21–30 years (30.14%) (p = 0.001). The majority of deaths were accidental (98.6%), with only one recorded case of suicide. Histopathological findings revealed inflammatory cell infiltration (20.5%) as the most frequent observation, followed by subcutaneous hemorrhage (13.7%) and cardiac myocyte damage (11%). Toxicological findings were negative in most of the cases (82%). Conclusions The study identifies young non-Saudi male workers as high-risk, underscoring the critical need for enhanced occupational safety protocols. Graphical Abstract
  • Postmortem forensic toxicology: a retrospective investigation from Dammam—Saudi Arabia
    Mohamed AlDossary, Ghada AlShamsi, Musaed AlFares, Hossam Alakhras, AbdulRahman Alsahab, et al.
    Egyptian Journal of Forensic Sciences, 2025
    Background Postmortem forensic toxicology is a critical discipline in forensic science, analyzing biological samples to detect and quantify drugs, alcohol, and other toxic substances in deceased individuals. This field plays a vital role in determining causes of death, investigating potential homicides, and identifying substance abuse trends in populations. With the rise in substance-related fatalities—driven by increasing misuse of both illicit and prescription drugs—postmortem toxicology has gained significant importance. This study examines postmortem forensic toxicology findings in Dammam, Saudi Arabia, from 2013 to 2022, analyzing cases referred to the Forensic Medicine Department to assess demographic patterns, causes of death, and toxicological profiles. Results The study included 387 cadavers, with the largest age group (35.1%) being 31–40 years, followed by 21–30 years (28.9%) and 41–50 years (22.7%). Most cases involved Saudi nationals (58.1%) and males (96.6%). Accidental deaths accounted for the majority (46.8%), while hanging suicides represented 22.5% of cases. Toxicological analysis revealed a high prevalence of polydrug use, underscoring its association with mortality. Conclusions The findings underscore the high incidence of drug-related deaths, especially involving polydrug use among Saudi males, and alcohol-related mortality among non-Saudis. These trends point to the urgent need for enhanced drug control measures, public education campaigns on substance abuse, and culturally tailored mental health interventions targeting high-risk groups. Graphical Abstract
  • Firearm fatalities in Dammam: A forensic retrospective study
    Magdy Kharoshah, Maram Aabdulghani AlFarayedhi, Abdullah AlBouijan, Noua AlOtaibi, AbdulRahman Waheed AlDossary, et al.
    Forensic Science International Reports, 2025
  • Toxicological impact of Thiamethoxam on adult male rats: Histopathological, biochemical, and oxidative DNA damage assessment
    Sahar Y. Issa, S.M. Abdel Rahman, Yasmin M. Gaber, Nada A.H. Soliman
    Toxicology Reports, 2025
  • Ethanol concentrations in various biological specimens: Living and postmortem forensic toxicology analysis and comprehensive literature review
    Sahar Y. Issa, Amr Khattab
    Journal of Forensic and Legal Medicine, 2024
  • Students' perception of private supplementary tutoring during medical undergraduate study in some Egyptian universities
    Sahar Issa, Heba Abd El Aaty, Yasmin Mohammed Gaber, Nancy M. Zaghloul
    Journal of Applied Research in Higher Education, 2023
    PurposeThe current work aimed to investigate the private tutoring phenomenon among Egyptian medical faculty students.Design/methodology/approachThe present work is a cross-sectional observational study using an online, anonymous questionnaire disseminated to Egyptian medical students and instructors via social platforms and university e-mails. All subjects involved in the survey gave informed consent to begin the questionnaire. No financial incentives were awarded to finish the questionnaire.FindingsIn total, 79.2% of the surveyed students (n = 198) admitted taking private medical courses during their medical study courses till the date of the survey. The Egyptian students, 68.4% (n = 171), markedly surpassed the non-Egyptian participants (n = 79, 31.6%). Males were nearly double the female participants (n = 162 and 88 consecutively).The highest academic-level-seeking private medical tutoring was the fifth-year students (n = 66, 26.4%).Research limitations/implicationsA large sample size is needed to strengthen the statistical power and permit the generalization over the population, so more research work in this aspect is recommended. Also, subject-specific data in private medical tutoring need to be investigated in future works. Similar global work is recommended to allow better comparison of data worldwide.Originality/valueWhen conceptualizing medical education processes and developing its regulations, the dynamics of private medical instruction should be taken into account, especially concerning socioeconomic inequities and efficiency in medical school systems. This work has been the first to investigate the private tutoring phenomenon among Egyptian medical students to the authors' best knowledge.
  • Technology facilitated sexual violence: a comparative study between working and non-working females in Egypt before and during the COVID-19 pandemic
    Nancy M. Zagloul, Rasha M. Farghaly, Hossam ELKhatib, Sahar Y. Issa, Safaa M. El-Zoghby
    Egyptian Journal of Forensic Sciences, 2022
    Background During the COVID-19 pandemic, quarantine measures policies increased Internet usage, leading to technological hazards as technology facilitated sexual violence (TFSV). Aim The current work aimed to assess TFSV among working and non-working Egyptian females before and during COVID-19. Methods The current work is a cross-sectional observational comparative study using an anonymous online questionnaire distributed through social platforms among working and non-working Egyptian females. Results TFSV was reported by 50.3% of the participants; however, regarding some forms of digital sexual violence, there was a significant decrease during COVID-19 lockdown than before it, considering; threatened creation form (7.8%, 12.0%; p = 0.017); non-consensual pornography (31.4%, 51.9%; p < 0.001) and online sexual harassment and cyber-stalking types (80.9%, 89.4%; p < 0.001). Only 17.3% of the study participants knew the identity of the perpetrator. TFSV led 6.4% to abstain from social media, and 3.9% reported the incident to a law agency. Conclusions The current study revealed that almost half of women experienced TFSV. Although time spent on the Internet by the whole participants during the pandemic was significantly higher than before, there was a significant decrease in some types of TFSV. The current study revealed that divorced females working in non-governmental sectors experienced harassment more significantly than others. There is crucial importance to set laws and penalties against perpetrators of TFSV to provide a safe technological environment for women.
  • Estimation of blood and urine levels of eight metals and essential trace elements collected from living Subjects compared to urine, cardiac and femoral postmortem blood, and other postmortem samples: A forensic toxicology study
    Sahar Y. Issa, Nancy M. Zaghloul, Maha K. Al Mazroua
    Journal of Forensic and Legal Medicine, 2022
  • Investigation on the elemental profiles of lip cosmetic products: Concentrations, distribution and assessment of potential carcinogenic and non-carcinogenic human health risk for consumer safety
    Heba Shaaban, Sahar Y. Issa, Rizwan Ahmad, Ahmed Mostafa, Sara Refai, et al.
    Saudi Pharmaceutical Journal, 2022
  • ICP-MS determination of elemental abundance in traditional medicinal plants commonly used in the Kingdom of Saudi Arabia
    Rizwan Ahmad, Heba Shaaban, Sahar Y. Issa, Anwar Alsaad, Majd Alghamdi, et al.
    Food Additives and Contaminants Part B Surveillance, 2022
  • Fully Automated Forensic Routine Dried Blood Spot Screening for Workplace Testing
    Stefan Gaugler, Maha K Al-Mazroua, Sahar Y Issa, Jana Rykl, Matthias Grill, et al.
    Journal of Analytical Toxicology, 2019
  • Corrigendum to: Fully automated forensic routine dried blood spot screening for workplace testing (Journal of Analytical Toxicology (2018) (1-9) DOI: 10.1093/jat/bky074)
    Stefan Gaugler, Maha K Al-Mazroua, Sahar Y Issa, Jana Rykl, Matthias Grill, et al.
    Journal of Analytical Toxicology, 2019
  • Baclofen systemic toxicity: Experimental histopathological and biochemical study
    SY Issa, EM Hafez, AS El-Banna, SM Abdel Rahman, MK AlMazroua, et al.
    Human and Experimental Toxicology, 2018
  • Stature estimation and sex prediction using measurements from forearm bones in adult Egyptians
    Sahar Y Issa, Ayman A Khanfour, Magdi Kharoshah
    Indian Journal of Forensic Medicine and Toxicology, 2017
  • Spectrum of unnatural deaths associated with positive toxicology findings in Eastern Province, KSA: An autopsy based study
    Sahar Y. Issa, Mohammed El Dossary, M. Abdel Salam, Maha K. Al-Mazroua, Mostafa A. Hamd, et al.
    Egyptian Journal of Forensic Sciences, 2016
  • Patterns of violent deaths associated with positive ethanol finding in Eastern Province, Saudi Arabia
    Sahar Y. Issa, Mohammed Aldossary, Maha K. Almazroua, Mohammed Abdel Salam Youssef, Sherien Ghaleb, et al.
    Egyptian Journal of Forensic Sciences, 2016
  • Suicidal deaths in depth-Eastern Province-Saudi Arabia
    Sahar Y. Issa, Mohammed El Dossary, M. Abdel Salam, Osama Al Madani, Maha K. AlMazroua, et al.
    Egyptian Journal of Forensic Sciences, 2016
  • A model for stature estimation and sex prediction using percutaneous ulnar and radial lengths in autopsied adult Egyptians
    Sahar Y. Issa, Ayman A. Khanfour, Magdy Kharoshah
    Egyptian Journal of Forensic Sciences, 2016