Sahar Younes Ibrahim Issa
@linkedin.com/in/sahar-issa-8675bb37
Department of Clinical Toxicology, Forensic Medicine & Medical Ethics, Faculty of Medicine, Alexandria University, Egypt
Professor of Forensic Medicine, Clinical Toxicology & Medical Ethics
Dr. Issa's research work exceeded 35 publications in both National & International Journals. She is interested in many areas of research focused on Drug Poisoning, Substances of Abuse, Designer Drugs, Forensic Toxicology, Electronic Health in Fields of Toxicology & Forensic Medicine, besides studying Systemic effects of acute toxicity related to drugs, herbs, Pesticides, and food.
Dr. Sahar presented oral talks and Poster presentations in many National and International Toxicology and Forensic sciences conferences and meetings. She is highly interested in investigating heavy metal poisonings, with interests in Lead Toxicity. She has been an She has been an Editorial board member and reviewer in many reputable medical National & International Journals in clinical, analytical, experimental toxicology, and forensic medicine.
She has a long expertise in Toxicology and forensic medicine fields exceeding 25 years in educational and governmental bodies inside & outside Egypt.
EDUCATION
Dr. Sahar Issa got her MSc (2001) and doctorate degrees (2009) in Clinical Toxicology and Forensic Medicine from Alexandria University-Egypt.
Her research work exceeded 35 publications in both National & International Journals. She is interested in many areas of research focused on Drug Poisoning, Substances of Abuse, Designer Drugs, Forensic Toxicology, Electronic Health in Fields of Toxicology & Forensic Medicine, besides studying Systemic effects of acute toxicity related to drugs, herbs, Pesticides, and food.
Dr. Sahar presented oral talks and Poster presentations in many National and International Toxicology and Forensic sciences conferences and meetings. She is highly interested in investigating heavy metal poisonings, with interests in Lead Toxicity.
RESEARCH, TEACHING, or OTHER INTERESTS
Medicine, Toxicology, Pathology and Forensic Medicine, Pharmacology, Toxicology and Pharmaceutics
Scopus Publications
Scholar Citations
Scholar h-index
Scholar i10-index
Scopus Publications
Sahar Issa, Heba Abd El Aaty, Yasmin Mohammed Gaber, and Nancy M. Zaghloul
Emerald
PurposeThe current work aimed to investigate the private tutoring phenomenon among Egyptian medical faculty students.Design/methodology/approachThe present work is a cross-sectional observational study using an online, anonymous questionnaire disseminated to Egyptian medical students and instructors via social platforms and university e-mails. All subjects involved in the survey gave informed consent to begin the questionnaire. No financial incentives were awarded to finish the questionnaire.FindingsIn total, 79.2% of the surveyed students (n = 198) admitted taking private medical courses during their medical study courses till the date of the survey. The Egyptian students, 68.4% (n = 171), markedly surpassed the non-Egyptian participants (n = 79, 31.6%). Males were nearly double the female participants (n = 162 and 88 consecutively).The highest academic-level-seeking private medical tutoring was the fifth-year students (n = 66, 26.4%).Research limitations/implicationsA large sample size is needed to strengthen the statistical power and permit the generalization over the population, so more research work in this aspect is recommended. Also, subject-specific data in private medical tutoring need to be investigated in future works. Similar global work is recommended to allow better comparison of data worldwide.Originality/valueWhen conceptualizing medical education processes and developing its regulations, the dynamics of private medical instruction should be taken into account, especially concerning socioeconomic inequities and efficiency in medical school systems. This work has been the first to investigate the private tutoring phenomenon among Egyptian medical students to the authors' best knowledge.
Nancy M. Zagloul, Rasha M. Farghaly, Hossam ELKhatib, Sahar Y. Issa, and Safaa M. El-Zoghby
Springer Science and Business Media LLC
Abstract Background During the COVID-19 pandemic, quarantine measures policies increased Internet usage, leading to technological hazards as technology facilitated sexual violence (TFSV). Aim The current work aimed to assess TFSV among working and non-working Egyptian females before and during COVID-19. Methods The current work is a cross-sectional observational comparative study using an anonymous online questionnaire distributed through social platforms among working and non-working Egyptian females. Results TFSV was reported by 50.3% of the participants; however, regarding some forms of digital sexual violence, there was a significant decrease during COVID-19 lockdown than before it, considering; threatened creation form (7.8%, 12.0%; p = 0.017); non-consensual pornography (31.4%, 51.9%; p < 0.001) and online sexual harassment and cyber-stalking types (80.9%, 89.4%; p < 0.001). Only 17.3% of the study participants knew the identity of the perpetrator. TFSV led 6.4% to abstain from social media, and 3.9% reported the incident to a law agency. Conclusions The current study revealed that almost half of women experienced TFSV. Although time spent on the Internet by the whole participants during the pandemic was significantly higher than before, there was a significant decrease in some types of TFSV. The current study revealed that divorced females working in non-governmental sectors experienced harassment more significantly than others. There is crucial importance to set laws and penalties against perpetrators of TFSV to provide a safe technological environment for women.
Sahar Y. Issa, Nancy M. Zaghloul, and Maha K. Al Mazroua
Elsevier BV
Heba Shaaban, Sahar Y. Issa, Rizwan Ahmad, Ahmed Mostafa, Sara Refai, Nooran Alkharraa, Batool T. Albaqshi, Dania Hussien, and Abdulmalik M. Alqarni
Elsevier BV
Rizwan Ahmad, Heba Shaaban, Sahar Y. Issa, Anwar Alsaad, Majd Alghamdi, Njoud Hamid, Rand Osama, Sara Algarni, Ahmed Mostafa, Abdulmalik M. Alqarni,et al.
Informa UK Limited
ABSTRACT Medicinal plants are widely used in the Kingdom of Saudi Arabia to treat various ailments in the form of folk medicine. Forty four such medicinal plant samples were collected from local markets and evaluated for the presence of 14 elements (Mn, Cr, Co, Ni, Cu, Mo, Al, Pb, Ba, Zn, Ag, Hg, Bi, Cd). Microwave-assisted digestion with inductively coupled plasma-mass spectrometry (ICP-MS) was applied to determine the elemental composition in these medicinal plants. Widespread occurrence of these elements was observed in all plant samples, except for Bi and Co where the lowest mean values of 0.03 ± 0.04 and 0.03 ± 0.15 were observed, respectively. The descending order for mean (μg/g) elemental occurrence observed was as follows: Ba > Al > Zn > Ni > Mn > Ba > Hg > Mo > Cu > Cr > Ag > Cd > Co > Bi, whereas the range for these elements in the 44-medicinal plants was as follows: Pb > Al > Zn > Ni > Mn > Cu > Mo > Ag > Ba > Hg > Co > Cd > Cr > Bi. Pb, Hg and Cd were found beyond the maximum limits in these medicinal plants, while the remaining elements were found well within the range of maximum limits. A number of medicinal plants showed high amounts of these elements. Some plants contained more than one element, such as Foeniculum vulgare Mill (Pb, Hg, Cd), Ricinus communis (Pb, Cd), Vigna radiata (Pb, Cd) and Sesamum indicum (Pb, Hg). The data matrix was validated through the statistical tools of principal component analysis (X2 = 160.44, P = .00), Pearson’s correlation (P = .01 and 0.05), and K-mean cluster analysis (F = 104.55, P = .00). The findings of the study provide baseline data for the comparative analysis of these medicinal plants, which may help select safe medicinal plants in terms of consumer-based use and its utilisation for the treatment of various ailments.
Stefan Gaugler, Maha K Al-Mazroua, Sahar Y Issa, Jana Rykl, Matthias Grill, Asem Qanair, and Vicente L Cebolla
Oxford University Press (OUP)
In this study, we describe the transfer of a new and fully automated workflow for the cost-effective drug screening of large populations based on the dried blood spot (DBS) technology. The method was installed at a routine poison control center and applied for DBS and dried urine spot (DUS) samples. A fast method focusing on the high-interest drugs and an extended screening method were developed on the automated platform. The dried cards were integrated into the automated workflow, in which the cards were checked in a camera recognition system, spiked with deuterated standards via an in-built spraying module and directly extracted. The extract was transferred online to an analytical LC column and then to the electrospray ionization tandem mass spectrometry system. The target compounds were analyzed in positive multiple-reaction monitoring mode. Before each sample batch or analysis day, calibration samples were measured to balance inter-day variations and to avoid false negative samples. An internal standard was integrated prior the sample extraction to allow in process control. A total of 28 target compounds were analyzed and directly extracted within 5 min per sample. This fast screening method was then extended to 20 min, enabling the usage of a Forensic Toxicology Database to screen over 1,200 drugs. The method gives confident positive/negative results for all tested drugs at their individual cut-off concentration. Good precision (±15%, respectively ±20% at limit of quantification) and correlation within the calibration range from 5 to 1,000 ng/mL was obtained. The method was finally applied to real cases from the lab and cross-checked with the existing methodologies.
Stefan Gaugler, Maha K Al-Mazroua, Sahar Y Issa, Jana Rykl, Matthias Grill, Asem Qanair, and Vicente L Cebolla
Oxford University Press (OUP)
SY Issa, EM Hafez, AS El-Banna, SM Abdel Rahman, MK AlMazroua, and MA El-Hamd
SAGE Publications
Objective: The present study was designed to highlight the toxic impact of baclofen on both biochemical and histopathological aspects in rats’ liver, gastric, lung, kidney, and brain tissues. Methods: The study was performed on 30 healthy adult male albino rats divided into four groups with 5 rats in each control group, and 10 rats in either experimental groups (two experimental and two control groups). Five rats (negative control) were kept in a quite non-stressful environment, provided with food ad libitum and free access to water. Normal saline (1 ml) was given orally as placebo in the positive control group (n = 5). Experimental group III, baclofen acute toxicity group (10 rats): Each animal received a single dose of lethal dose (LD50) of baclofen orally by gavage. It equals 145 mg/kg body weight. The rats were observed for acute toxicity manifestations as well as for LD50 deaths. Group IV, (baclofen-dependent group, 10 rats): Each animal received baclofen (1/10th LD50) in gradually increasing doses for 1 month. Results: The levels of blood urea nitrogen, creatinine kinase, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, γ-glutamyl transpeptidase, cardiac troponin I, and prothrombin time in both baclofen-treated groups showed significant elevation when compared to controls. There were brain, lung, gastric, hepatic, and renal histopathological changes in baclofen-treated rats whose severity varied between the two experimental groups. Conclusion and recommendation: Baclofen toxicity is an under diagnosed emergency. Physicians should consider baclofen toxicity in users having hepatorenal dysfunction, presenting with altered mental status, bradycardia, and hypotension.
Sahar Y Issa, Ayman A Khanfour, and Magdi Kharoshah
Diva Enterprises Private Limited
Identification of unknown cadavers by constructing a biological profile from their skeletal remains is one of the main aims of any forensic pathologist. But yet, there are no organized studies are yet available for gender and height estimation in adult Egyptians.
Sahar Y. Issa, Mohammed El Dossary, M. Abdel Salam, Maha K. Al-Mazroua, Mostafa A. Hamd, and M. Kharoshah
Springer Science and Business Media LLC
Sahar Y. Issa, Mohammed Aldossary, Maha K. Almazroua, Mohammed Abdel Salam Youssef, Sherien Ghaleb, Kholuod Alsowayigh, Mostafa A. Hamd, and Magdy Kharoshah
Springer Science and Business Media LLC
Sahar Y. Issa, Mohammed El Dossary, M. Abdel Salam, Osama Al Madani, Maha K. AlMazroua, Kholoud Alsowayigh, Mostafa A. Hamd, Amany H. AboZayed, and Magdy Kharoshah
Springer Science and Business Media LLC
Sahar Y. Issa, Ayman A. Khanfour, and Magdy Kharoshah
Springer Science and Business Media LLC