Sunilkumar Bhavsar

@vnsgu.ac.in

Veer Narmad South Gujarat University
Veer Narmad South Gujarat University

Sunilkumar Bhavsar


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https://researchid.co/ssunil48

RESEARCH, TEACHING, or OTHER INTERESTS

Biochemistry, Genetics and Molecular Biology, Biotechnology, Agricultural and Biological Sciences, Spectroscopy
6

Scopus Publications

162

Scholar Citations

6

Scholar h-index

5

Scholar i10-index

Scopus Publications

  • Green synthesis of silver nanoparticles by Kocuria flava isolated from photovoltaic panels for combating infections, cancer, and water pollution
    Vishal Prajapati, Dhanusha Panchal, Manisha Dikshit, Rajesh Patel, Sunil Bhavsar, Ashish Patel, Dipak Kumar Sahoo, Kuldeep Luhana
    Frontiers in Microbiology, 2025
    The extremophilic bacterial community associated with photovoltaic solar panels has demonstrated significant resilience to harsh environmental conditions such as desiccation, thermal fluctuations, and intense solar exposure. The bacterial strain Kocuria flava KKYHNGU1 was isolated from a PV panel and characterized for its resistance to alkaline pH (pH 9), salinity (1–9% w/v), UV radiation (approximately 8 min), and high temperatures (up to 55 °C). Bio-manufactured AgNPs from this isolate were characterized, including UV–visible spectroscopy (with wavelength peaks at 437 nm), FTIR, and X-ray diffraction, validating the crystalline configuration of the AgNPs, exhibiting intensity peaks at 28.02°, 32.46°, and 46.36°. The spherical shape and size (96 nm diameter) along with the silver content (87.06% w/w) of bio-synthesized AgNPs was confirmed through scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy. Metabolomic analysis through LC-MS revealed the presence of bioactive compounds possessing significant antimicrobial and anti-cancer properties, in addition to marked reduction capabilities. They have manifested notable antibacterial potential against Staphylococcus aureus with a 14 mm zone of inhibition and also proved effectiveness against Serratia marcescens , Bacillus cereus , and Escherichia coli . Additionally, the AgNPs effectively removed trimethoprim, achieving a 63.42% removal at 10 ppm within 120 min. These bio-fabricated AgNPs displayed remarkable anti-proliferative and pro-apoptotic activity against the THP-1 monocytic leukemia cell line, yielding an IC50 measurement of 40 μg/mL. These findings underscore the prospective applications of biogenic AgNPs in wastewater treatment and biomedical fields, illustrating their multiple functionalities.
  • Oxalic Acid-Assisted Photo-Fenton Catalysis Using Magnetic Fe3O4 Nanoparticles for Complete Removal of Textile Dye
    Sunil Bhavsar, Pravin Dudhagara, Anjana Ghelani, I Nengah Wirajana, Quyet-Tien Phi, Yih-Yuan Chen, Douglas J. H. Shyu
    Chemengineering, 2024
    Textile industry effluents contain several hazardous substances, such as dye-containing effluents, which pose environmental and aesthetic challenges. Presently, the microbial-based remediation process is in use. This study investigated the application of ferrous–ferric oxide (Fe3O4) nanoparticles, a readily formulated nanoadsorbent, to remove scattered dye molecules from industrial effluents. The ferrous–ferric oxide nanoparticles were prepared using a chemical co-precipitation method. The nanoparticles had 26.93 emu g−1 magnetization, with sizes smaller than 20 nm, and possessed a highly purified cubic spinel crystallite structure. The catalytic activity of the iron oxide depended on the dose, photocatalytic enhancer, i.e., H2O2 level, pH of the reaction medium, and dye concentration. We optimized the Fenton-like reaction to work best using 1.0 g/L of ferrous–ferric oxide nanoparticles, 60 mM oxalic acid at pH 7.0, and 60 ppm of dye. Iron oxides act as photocatalysts, and oxalic acid generates electron–hole pairs. Consequently, higher amounts of super-radicals cause the rapid degradation of dye and pseudo-first-order reactions. Liquid chromatography–mass spectrometry (LC-MS) analysis revealed the ferrous–ferric oxide nanoparticles decolorized and destroyed Disperse Red 277 in 180 min under visible light. Hence, complete demineralization is observed using a photo-Fenton-like reaction within 3 h under visible light. These high-capacity, easy-to-separate next-generation adsorption systems are suggested to be suitable for industrial-scale use. Ferrous–ferric oxide nanoparticles with increased adsorption and magnetic properties could be utilized to clean environmental pollution.
  • R software package based statistical optimization of process components to simultaneously enhance the bacterial growth, laccase production and textile dye decolorization with cytotoxicity study
    Sunil Bhavsar, Pravin Dudhagara, Shantilal Tank
    Plos One, 2018
    The thermophilic bacterium, Bacillus licheniformis U1 is used for the optimization of bacterial growth (R1), laccase production (R2) and synthetic disperse blue DBR textile dye decolorization (R3) in the present study. Preliminary optimization has been performed by one variable at time (OVAT) approach using four media components viz., dye concentration, copper sulphate concentration, pH, and inoculum size. Based on OVAT result further statistical optimization of R1, R2 and R3 performed by Box–Behnken design (BBD) using response surface methodology (RSM) in R software with R Commander package. The total 29 experimental runs conducted in the experimental design study towards the construction of a quadratic model. The model indicated that dye concentration 110 ppm, copper sulphate 0.2 mM, pH 7.5 and inoculum size 6% v/v were found to be optimum to maximize the laccase production and bacterial growth. Whereas, maximum dye decolorization achieved in media containing dye concentration 110 ppm, copper sulphate 0.6 mM, pH 6 and inoculum size 6% v/v. R package predicted R2 of R1, R2 and R3 were 0.9917, 0.9831 and 0.9703 respectively; likened to Design-Expert (Stat-Ease) (DOE) predicted R2 of R1, R2, and R3 were 0.9893, 0.9822 and 0.8442 respectively. The values obtained by R software were more precise, reliable and reproducible, compared to the DOE model. The laccase production was 1.80 fold increased, and 2.24 fold enhancement in dye decolorization was achieved using optimized medium than initial experiments. Moreover, the laccase-treated sample demonstrated the less cytotoxic effect on L132 and MCF-7 cell lines compared to untreated sample using MTT assay. Higher cell viability and lower cytotoxicity observed in a laccase-treated sample suggest the impending application of bacterial laccase in the reduction of toxicity of dye to design rapid biodegradation process.
  • Metagenomic data of fungal internal transcribed Spacer and 18S rRNA gene sequences from Lonar lake sediment, India
    Pravin Dudhagara, Anjana Ghelani, Sunil Bhavsar, Shreyas Bhatt
    Data in Brief, 2015
    The data in this article contains the sequences of fungal Internal Transcribed Spacer (ITS) and 18S rRNA gene from a metagenome of Lonar soda lake, India. Sequences were amplified using fungal specific primers, which amplified the amplicon lined between the 18S and 28S rRNA genes. Data were obtained using Fungal tag-encoded FLX amplicon pyrosequencing (fTEFAP) technique and used to analyze fungal profile by the culture-independent method. Primary analysis using PlutoF 454 pipeline suggests the Lonar lake mycobiome contained the 29 different fungal species. The raw sequencing data used to perform this analysis along with FASTQ file are located in the NCBI Sequence Read Archive (SRA) under accession No. SRX889598 (http://www.ncbi.nlm.nih.gov/sra/SRX889598).
  • Assessment of genetic purity of parental lines of hybrid rice using DNA-based markers
    Sunil Bhavsar, Twinkle Solanki, Suchita Amin, Neeru Jain
    Online Journal of Biological Sciences, 2015
    Assessment of hybrid seed genetic purity is one of the most important quality control parameters in hybrid seed production. With the objective of replacing the GOT with DNA based assays, Cytoplasmic Male Sterile (CMS), restorer and hybrid lines have been screened by means of microsatellite and Sequence Tagged Site (STS) markers. Cytoplasmic Male Sterile (CMS) lines often get contaminated with cognate isonuclear maintainer lines during multiplication. The PCR assay was able to detect precisely the impurities in a commercial seed lot of CMS line. The extent of heterozygosity within parental lines of rice hybrids were assessed and the results suggest that a single, appropriately chosen microsatellite marker should be sufficient for assessing hybrid seed purity.
  • Web Resources for Metagenomics Studies
    Pravin Dudhagara, Sunil Bhavsar, Chintan Bhagat, Anjana Ghelani, Shreyas Bhatt, Rajesh Patel
    Genomics Proteomics and Bioinformatics, 2015
    The development of next-generation sequencing (NGS) platforms spawned an enormous volume of data. This explosion in data has unearthed new scalability challenges for existing bioinformatics tools. The analysis of metagenomic sequences using bioinformatics pipelines is complicated by the substantial complexity of these data. In this article, we review several commonly-used online tools for metagenomics data analysis with respect to their quality and detail of analysis using simulated metagenomics data. There are at least a dozen such software tools presently available in the public domain. Among them, MGRAST, IMG/M, and METAVIR are the most well-known tools according to the number of citations by peer-reviewed scientific media up to mid-2015. Here, we describe 12 online tools with respect to their web link, annotation pipelines, clustering methods, online user support, and availability of data storage. We have also done the rating for each tool to screen more potential and preferential tools and evaluated five best tools using synthetic metagenome. The article comprehensively deals with the contemporary problems and the prospects of metagenomics from a bioinformatics viewpoint.

RECENT SCHOLAR PUBLICATIONS

  • Green synthesis of silver nanoparticles by Kocuria flava isolated from photovoltaic panels for combating infections, cancer, and water pollution
    V Prajapati, D Panchal, M Dikshit, R Patel, S Bhavsar, A Patel, DK Sahoo, ...
    Frontiers in Microbiology 16, 1658320 , 2025
    2025.0
  • Oxalic Acid-Assisted Photo-Fenton Catalysis Using Magnetic Fe 3 O 4 Nanoparticles for Complete Removal of Textile Dye
    S Bhavsar, P Dudhagara, A Ghelani, IN Wirajana, QT Phi, YY Chen, ...
    ChemEngineering 8 (4), 67 , 2024
    2024.0
    Citations: 6
  • Response surface designs and R package based modelling for predictive capabilities, sensitivity and validation of model for improving the bacterial growth, laccase production …
    P Dudhagara, S Bhavsar
    Biomath Communications Supplement , 2023
    2023.0
  • Effect of different calcium salts on calcium carbonates formation induced by Halophilic Bacillus oceanisediminis CB1
    A Ghelani
    Acta Chimica Asiana , 2022
    2022.0
    Citations: 1
  • R software package based statistical optimization of process components to simultaneously enhance the bacterial growth, laccase production and textile dye decolorization with …
    ST Sunil Bhavsar, Pravin Dudhagara
    PLOS ONE 13 (5), e0195795 , 2018
    2018.0
    Citations: 35
  • Effect of SOx and NOx on carbonic anhydrase mediated calcium utilization
    C Bhagat, S Bhavsar, S Tank
    IJRAR 5, 381-385 , 2018
    2018.0
    Citations: 1
  • Web resources for metagenomics studies
    P Dudhagara, S Bhavsar, C Bhagat, A Ghelani, S Bhatt, R Patel
    Genomics, proteomics & bioinformatics 13 (5), 296-303 , 2015
    2015.0
    Citations: 63
  • Hide dehairing and laundry detergent compatibility testing of thermostable and solvents tolerant alkaline protease from hot spring isolate Bacillus cohnii U3
    PR Dudhgara, B Sunil, G Anjana
    Online J Biol Sci 15 (3), 152-161 , 2015
    2015.0
    Citations: 13
  • Metagenomic data of fungal internal transcribed Spacer and 18S rRNA gene sequences from Lonar lake sediment, India
    P Dudhagara, A Ghelani, S Bhavsar, S Bhatt
    Data in brief 4, 266 , 2015
    2015.0
    Citations: 12
  • Assessment of Genetic Purity of Parental Lines of Hybrid Rice Using DNA-Based Markers
    S Bhavsar, T Solanki, S Amin, N Jain
    OnLine Journal of Biological Sciences 15 (2), 59 , 2015
    2015.0
    Citations: 5
  • Author's Accepted Manuscript
    P Dudhagara, A Ghelani, S Bhavsar, S Bhatt
    2015.0
  • Evaluation of heavy metals pollution quest of idol immersion in the river Tapti through environmetrics
    B Sunil, T Titus, T Vivek, Dube, Shantilal
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCES 4 (5), 974-982 , 2014
    2014.0
    Citations: 1
  • Isolation, characterization and investing the industrial applications of thermostable and solvent tolerant serine protease from hot spring isolated thermophililic Bacillus …
    P Dudhagara, S Bhavasar, A Ghelani, S Bhatt
    International Journal of Applied Sciences and Biotechnology 2 (1), 75-82 , 2014
    2014.0
    Citations: 25
  • In Silico Prediction of MicroRNA in Hepatitis Delta Virus Genome
    SP Bhavsar, PR Dudhagara
    Bioinfrmatica 1 (1) , 2012
    2012.0
  • Isolation, Characterization and investing the Industrial Applications of Thermostable and Solvent Tolerant Serine Protease...
    SP Bhavsar, PR Dudhagara, G Anjana, S Bhatt

MOST CITED SCHOLAR PUBLICATIONS

  • Web resources for metagenomics studies
    P Dudhagara, S Bhavsar, C Bhagat, A Ghelani, S Bhatt, R Patel
    Genomics, proteomics & bioinformatics 13 (5), 296-303 , 2015
    2015.0
    Citations: 63
  • R software package based statistical optimization of process components to simultaneously enhance the bacterial growth, laccase production and textile dye decolorization with …
    ST Sunil Bhavsar, Pravin Dudhagara
    PLOS ONE 13 (5), e0195795 , 2018
    2018.0
    Citations: 35
  • Isolation, characterization and investing the industrial applications of thermostable and solvent tolerant serine protease from hot spring isolated thermophililic Bacillus …
    P Dudhagara, S Bhavasar, A Ghelani, S Bhatt
    International Journal of Applied Sciences and Biotechnology 2 (1), 75-82 , 2014
    2014.0
    Citations: 25
  • Hide dehairing and laundry detergent compatibility testing of thermostable and solvents tolerant alkaline protease from hot spring isolate Bacillus cohnii U3
    PR Dudhgara, B Sunil, G Anjana
    Online J Biol Sci 15 (3), 152-161 , 2015
    2015.0
    Citations: 13
  • Metagenomic data of fungal internal transcribed Spacer and 18S rRNA gene sequences from Lonar lake sediment, India
    P Dudhagara, A Ghelani, S Bhavsar, S Bhatt
    Data in brief 4, 266 , 2015
    2015.0
    Citations: 12
  • Oxalic Acid-Assisted Photo-Fenton Catalysis Using Magnetic Fe 3 O 4 Nanoparticles for Complete Removal of Textile Dye
    S Bhavsar, P Dudhagara, A Ghelani, IN Wirajana, QT Phi, YY Chen, ...
    ChemEngineering 8 (4), 67 , 2024
    2024.0
    Citations: 6
  • Assessment of Genetic Purity of Parental Lines of Hybrid Rice Using DNA-Based Markers
    S Bhavsar, T Solanki, S Amin, N Jain
    OnLine Journal of Biological Sciences 15 (2), 59 , 2015
    2015.0
    Citations: 5
  • Effect of different calcium salts on calcium carbonates formation induced by Halophilic Bacillus oceanisediminis CB1
    A Ghelani
    Acta Chimica Asiana , 2022
    2022.0
    Citations: 1
  • Effect of SOx and NOx on carbonic anhydrase mediated calcium utilization
    C Bhagat, S Bhavsar, S Tank
    IJRAR 5, 381-385 , 2018
    2018.0
    Citations: 1
  • Evaluation of heavy metals pollution quest of idol immersion in the river Tapti through environmetrics
    B Sunil, T Titus, T Vivek, Dube, Shantilal
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCES 4 (5), 974-982 , 2014
    2014.0
    Citations: 1
  • Green synthesis of silver nanoparticles by Kocuria flava isolated from photovoltaic panels for combating infections, cancer, and water pollution
    V Prajapati, D Panchal, M Dikshit, R Patel, S Bhavsar, A Patel, DK Sahoo, ...
    Frontiers in Microbiology 16, 1658320 , 2025
    2025.0
  • Response surface designs and R package based modelling for predictive capabilities, sensitivity and validation of model for improving the bacterial growth, laccase production …
    P Dudhagara, S Bhavsar
    Biomath Communications Supplement , 2023
    2023.0
  • Author's Accepted Manuscript
    P Dudhagara, A Ghelani, S Bhavsar, S Bhatt
    2015.0
  • In Silico Prediction of MicroRNA in Hepatitis Delta Virus Genome
    SP Bhavsar, PR Dudhagara
    Bioinfrmatica 1 (1) , 2012
    2012.0
  • Isolation, Characterization and investing the Industrial Applications of Thermostable and Solvent Tolerant Serine Protease...
    SP Bhavsar, PR Dudhagara, G Anjana, S Bhatt