Suzy ElSherbeni

@tdb2.tanta.edu.eg

Department of Pharmcognosy
Faculty of Pharmacy, Tanta University

Suzy ElSherbeni


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https://researchid.co/suzyelsherbeni

EDUCATION

Doctor of Philosophy degree of Pharmaceutical Sciences (Pharmacognosy), 2015, Faculty of Pharmacy, Tanta University, Egypt.
Associate Professor of Pharmacognosy, 2022, Faculty of Pharmacy, Tanta University, Egypt.

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacy, Plant Science
19

Scopus Publications

525

Scholar Citations

11

Scholar h-index

11

Scholar i10-index

Scopus Publications

  • Phytochemicals of Vitis vinifera L. var. King Ruby protect mice from benzo(a)pyrene-induced lung injury
    Gehad S. Ahmedy, Hend M. Selim, Mona El-Aasr, Souzan M. Ibrahim, Suzy A. El-Sherbeni
    Scientific Reports, 2025
    The world’s concern about smoking hazards, chronic obstructive pulmonary disease (COPD) and lung cancer was the motivation to investigate plants as a source of new drugs with lung protective effect. The phytochemical profile of Vitis vinifera L. var. King Ruby leaves methanol extract (VLME) was tentatively recognized by liquid chromatography electrospray ionization tandem mass spectrometric (LC-ESI-MS/MS). Fifty-two and forty-seven compounds were identified by negative and positive ESI modes, respectively. Taraxerol (1), β-sitosterol (2), daucosterol (3), quercetin-3-O-β-D-glucuronoide-6″-methyl ester (4) and isoquercetin (5) were isolated from VLME. The sulforhodamine B (SRB) assay of the different fractions against A-549 cell line revealed that the methylene chloride fraction (MCF) had the lowest cell viability at 300 µg/mL (4.54 ± 0.19%). Mice of 10 groups (n = 6) was treated as follows: Group I (negative control group), group II (disease control, mice received B(a)P 125 mg/kg, orally), groups III-V (mice received 100, 200, and 300 mg/kg of VLME, followed by B(a)P), group VI (mice received only 300 mg/kg of VLME), groups VII-XI (mice received 100, 200, and 300 mg/kg of MCF, followed by B(a)P), group X (mice received only 300 mg/kg of MCF). On the seventh day, all groups received a single oral dose of B(a)P 125 mg/kg body, except group I, VI and X. In vivo studies showed VLME and MCF (300 mg/kg body weight) effectively mitigated benzo(a)pyrene-induced lung injuries in mice. The anti-inflammatory effects were confirmed by the downregulation of cyclooxygenase-2 (COX-2) and CD34, alongside reduced nuclear factor-kappa B (NF-κB) expression. Antioxidant activity was indicated by decreased malondialdehyde (MDA) levels and inducible nitric oxide synthase (iNOS) expression with the remarkable increase in glutathione (GSH). Histological improvements further support the potential of Vitis vinifera L. leaves as a natural lung protectant. Further pre-clinical and clinical investigations will be required to deliver a new drug with promising protection effect.
  • Potential Surviving Effect of Cleome droserifolia Extract against Systemic Staphylococcus aureus Infection: Investigation of the Chemical Content of the Plant
    Jawaher Alqahtani, Walaa A. Negm, Engy Elekhnawy, Ismail A. Hussein, Hassan Samy Hassan, et al.
    Antibiotics, 2024
    The increasing rates of morbidity and mortality owing to bacterial infections, particularly Staphylococcus aureus have necessitated finding solutions to face this issue. Thus, we elucidated the phytochemical constituents and antibacterial potential of Cleome droserifolia extract (CDE). Using LC-ESI-MS/MS, the main phytoconstituents of CDE were explored, which were kaempferol-3,7-O-bis-alpha-L-rhamnoside, isorhamnetin, cyanidin-3-glucoside, kaempferide, kaempferol-3-O-alpha-L-rhamnoside, caffeic acid, isoquercitrin, quinic acid, isocitrate, mannitol, apigenin, acacetin, and naringenin. The CDE exerted an antibacterial action on S. aureus isolates with minimum inhibitory concentrations ranging from 128 to 512 µg/mL. Also, CDE exhibited antibiofilm action using a crystal violet assay. A scanning electron microscope was employed to illuminate the effect of CDE on biofilm formation, and it considerably diminished S. aureus cell number in the biofilm. Moreover, qRT-PCR was performed to study the effect of CDE on biofilm gene expression (cna, fnbA, and icaA). The CDE revealed a downregulating effect on the studied biofilm genes in 43.48% of S. aureus isolates. Regarding the in vivo model, CDE significantly decreased the S. aureus burden in the liver and spleen of CDE-treated mice. Also, it significantly improved the mice’s survival and substantially decreased the inflammatory markers (interleukin one beta and interleukin six) in the studied tissues. Furthermore, CDE has improved the histology and tumor necrosis factor alpha immunohistochemistry in the liver and spleen of the CDE-treated group. Thus, CDE could be considered a promising candidate for future antimicrobial drug discovery studies.
  • The effects of cholesterol and statins on Parkinson’s neuropathology: a narrative review
    Hayder M. Al-kuraishy, Esraa H. Fahad, Salah Al-Windy, Suzy A. El-Sherbeni, Walaa A. Negm, et al.
    Inflammopharmacology, 2024
  • Chemotherapeutic effect of baicalein/epirubicin combination against liver cell carcinoma in-vitro: Inducing apoptosis and autophagy
    Ghada Mohammad Al-Ashmawy, Suzy Abd El-Hakeem El-Sherbeni, Dina Adam Ali, Mariam Ali Abo-Saif
    Toxicology in Vitro, 2024
  • Outlining the Phytoconstituents of Greek Clover Herb Extract and Assessment of Its Effect against Foodborne Infections Caused by Salmonella typhimurium
    Jawaher Alqahtani, Walaa A. Negm, Engy Elekhnawy, Moneerah J. Alqahtani, Ehssan Moglad, et al.
    Pharmaceuticals, 2024
    Owing to the spread of resistance between pathogenic bacteria, searching for novel compounds with antibacterial activity is essential. Here, we investigated the potential antibacterial activity of Greek clover or Trigonella foenum-graecum herb extract on Salmonella typhimurium clinical isolates. The chemical profile of the herb was initially determined using LC-ESI-MS/MS, which explored 36 different compounds. Interestingly, the fenugreek extract possessed antibacterial action in vitro with minimum inhibitory concentrations of 64 to 512 µg/mL. The potential mechanism of action was studied by elucidating the effect of the fenugreek extract on the membrane properties of S. typhimurium bacteria, including the inner and outer membrane permeability and membrane integrity. Remarkably, the fenugreek extract had detrimental effects on the membrane properties in 40–60% of the isolates. Moreover, the in vivo antibacterial action was studied using a gastrointestinal infection model with S. typhimurium bacteria. Interestingly, the fenugreek extract (200 mg/kg) improved the infection outcomes in the tested mice. This was represented by the noteworthy decrease (p < 0.05) in the bacterial count in the small intestine and caecum tissues. The survival rate of the fenugreek-extract-treated mice significantly increased compared to the S. typhimurium-infected group. Additionally, there was an improvement in the histological and immunohistochemical features of tumor necrosis factor-alpha. In addition, using an ELISA and qRT-PCR, there was an improvement in the proinflammatory and oxidative stress markers in the fenugreek-extract-treated group. Consequently, fenugreek extract should be investigated further on other food pathogens.
  • The wound healing effect of botanicals and pure natural substances used in in vivo models
    S. A. El-Sherbeni, W. A. Negm
    Inflammopharmacology, 2023
    Repairing the wound is a multistep process that includes the spatial and temporal synchronization of a different range of cell types to increase the speed of wound contraction, the proliferation of epithelial cells, and collagen formation. The need for proper management of acute wounds to be cured and not turned into chronic wounds is a significant clinical challenge. The traditional practice of medicinal plants in many regions of the world has been used in wound healing since ancient times. Recent scientific research introduced evidence of the efficacy of medicinal plants, their phyto-components, and the mechanisms underlying their wound-repairing activity. This review aims to briefly highlight the wound-curing effect of different plant extracts and purely natural substances in excision, incision, and burn experimental animal models with or without infection of mice, rats (diabetic and nondiabetic), and rabbits in the last 5 years. The in vivo studies represented reliable evidence of how powerful natural products are in healing wounds properly. They have good scavenging activity against Reactive oxygen species (ROS) and anti-inflammatory and antimicrobial effects that help in the process of wound healing. It is evident that incorporating bioactive natural products into wound dressings of bio- or synthetic polymers in nanofiber, hydrogel, film, scaffold, and sponge forms showed promising results in different phases of the wound-curing process of haemostasis, inflammation, growth, re-epithelialization, and remodelling.
  • In Vitro Antiviral Effect and Potential Neuroprotection of Salvadora persica L. Stem Bark Extract against Lipopolysaccharides-Induced Neuroinflammation in Mice: LC-ESI-MS/MS Analysis of the Methanol Extract
    Reem Binsuwaidan, Walaa A. Negm, Engy Elekhnawy, Nashwah G. M. Attallah, Eman Ahmed, et al.
    Pharmaceuticals, 2023
    Neuroinflammation is a serious immunomodulatory complex disorder that causes neurological and somatic ailments. The treatment of brain inflammation with new drugs derived from natural sources is a significant therapeutic goal. Utilizing LC-ESI-MS/MS analysis, the active constituents of Salvadora persica extract (SPE) were identified tentatively as exerting antioxidant and anti-inflammatory effects in natural medicine. Herein, we determined the antiviral potential of SPE against herpes simplex virus type 2 (HSV-2) using the plaque assay. HSV-2 is a neurotropic virus that can cause neurological diseases. SPE exhibited promising antiviral potential with a half-maximal cytotoxic concentration (CC50) of 185.960 ± 0.1 µg/mL and a half-maximal inhibitory concentration (IC50) of 8.946 ± 0.02 µg/mL. The in vivo study of the SPE impact against lipopolysaccharide (LPS)-induced neuroinflammation was performed using 42 mice divided into seven groups. All groups were administered LPS (0.25 mg/kg) intraperitoneally, except for the normal and SPE groups 1 and 2. Groups 5, 6, and 7 received 100, 200, and 300 mg/kg SPE. It was revealed that SPE inhibited acetylcholinesterase in the brain. It increased superoxide dismutase and catalase while decreasing malondialdehyde, which explains its antioxidative stress activity. SPE downregulated the gene expression of the inducible nitric oxide synthase, as well as the apoptotic markers (caspase-3 and c-Jun). In addition, it decreased the expression of the proinflammatory cytokines (interleukin-6 and tumor necrosis factor-alpha). Mice administered SPE (300 mg/kg) with LPS exhibited normal neurons in the cerebral cortices, hippocampus pyramidal layer, and cerebellum, as determined by the histopathological analysis. Therefore, using S. persica to prevent and treat neurodegeneration could be a promising new therapeutic strategy to be explored.
  • A perspective study of the possible impact of obeticholic acid against SARS-CoV-2 infection
    Gaber El-Saber Batiha, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Fadia S. Youssef, Suzy A. El-Sherbeni, et al.
    Inflammopharmacology, 2023
    The causative agent of CoV disease 2019 is a new coronavirus CoV type 2, affecting the respiratory tract with severe manifestations (SARS-CoV-2). Covid-19 is mainly symptomless, with slight indications in about 85% of the affected cases. Many efforts were done to face this pandemic by testing different drugs and agents to make treatment protocols in different countries. However, the use of these proposed drugs is associated with the development of adverse events. Remarkably, the successive development of SARS-CoV-2 variants which could affect persons even they were vaccinated, prerequisite wide search to find efficient and safe agents to face SARS-CoV-2 infection. Obeticholic acid (OCA), which has anti-inflammatory effects, may efficiently treat Covid-19. Thus, the goal of this perspective study is to focus on the possible medicinal effectiveness in managing Covid-19. OCA is a powerful farnesoid X receptor (FXR) agonist possessing marked antiviral and anti-inflammatory effects. FXR is dysregulated in Covid-19 resulting in hyper-inflammation with concurrent occurrence of hypercytokinemia. Interestingly, OCA inhibits the reaction between this virus and angiotensin-converting enzyme type 2 (ACE2) receptors. FXR agonists control the expression of ACE2 and the inflammatory signaling pathways in this respiratory syndrome, which weakens the effects of Covid-19 disease and accompanied complications. Taken together, FXR agonists like OCA may reveal both direct and indirect impacts in the modulation of immune reaction in SARS-CoV-2 conditions. It is highly recommended to perform many investigations regarding different phases of the discovery of new drugs.
  • Elucidation of Natural Components of Gardenia thunbergia Thunb. Leaves: Effect of Methanol Extract and Rutin on Non-Alcoholic Fatty Liver Disease
    Eman M. EL-Shial, Amal Kabbash, Mona El-Aasr, Ola A. El-Feky, Suzy A. El-Sherbeni
    Molecules, 2023
    The rising prevalence of non-alcoholic fatty liver disease NAFLD has strained the healthcare system. Natural products could solve this problem, so the current study focused on the impact of G. thunbergia Thunb. against this ailment. LC–ESI–MS/MS revealed the phytochemical profile of the methanol extract from Gardenia thunbergia leaves (GME). Forty-eight compounds were tentatively identified, and stigmasterol, fucosterol, ursolic acid, and rutin were isolated. The separation of the last three compounds from this plant had not before been achieved. The anti-NAFLD effect of the methanol extract of the leaves of G. thunbergia, and its major metabolite, rutin, was assessed in mice against high-fructose diet (HFD)-induced obesity. Male mice were allocated into nine groups: (1) saline (control), (2) 30% fructose (diseased group), (3) HFD, and 10 mg/kg of simvastatin. Groups 4–6 were administered HFD and rutin 50, 75, and 100 mg/kg. Groups (7–9) were administered HFD and methanol extract of leaves 100, 200, and 300 mg/kg. Methanol extract of G. thunbergia leaves at 200 mg/kg, and rutin at 75 mg/kg significantly reduced HFD-induced increments in mice weight and hepatic damage indicators (AST and ALT), steatosis, and hypertrophy. The levels of total cholesterol, LDL–C, and triglycerides in the blood decreased. In addition, the expressions of CYP2E1, JNK1, and iNOS in the diseased mice were downregulated. This study found that GME and rutin could ameliorate NAFLD in HFD-fed mice, with results comparable to simvastatin, validating G. thunbergia’s hepatoprotective effects.
  • Assessment of drugs administered in the Middle East as part of the COVID-19 management protocols
    Engy Elekhnawy, Walaa A. Negm, Suzy A. El-Sherbeni, Ahmed Zayed
    Inflammopharmacology, 2022
    The pandemic spread of coronavirus (COVID-19) has been reported first at the end of 2019. It continues disturbing various human aspects with multiple pandemic waves showing more fatal novel variants. Now Egypt faces the sixth wave of the pandemic with controlled governmental measures. COVID-19 is an infectious respiratory disease-causing mild to moderate illness that can be progressed into life-threatening complications based on patients- and variant type-related factors. The symptoms vary from dry cough, fever to difficulty in breathing that required urgent hospitalization. Most countries have authorized their national protocols for managing manifested symptoms and thus lowering the rate of patients’ hospitalization and boosting the healthcare systems. These protocols are still in use even with the development and approval of several vaccines. These protocols were instructed to aid home isolation, bed rest, dietary supplements, and additionally the administration of antipyretic, steroids, and antiviral drugs. The current review aimed to highlight the administered protocols in the Middle East, namely in Egypt and the Kingdom of Saudi Arabia demonstrating how these protocols have shown potential effectiveness in treating patients and saving many soles.
  • Bilosomes as Nanoplatform for Oral Delivery and Modulated In Vivo Antimicrobial Activity of Lycopene
    Reem Binsuwaidan, Amal A. Sultan, Walaa A. Negm, Nashwah G. M. Attallah, Moneerah J. Alqahtani, et al.
    Pharmaceuticals, 2022
  • Elucidation of the Metabolite Profile of Yucca gigantea and Assessment of its Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities
    Nashwah G. M. Attallah, Suzy A. El-Sherbeni, Aya H. El-Kadem, Engy Elekhnawy, Thanaa A. El-Masry, et al.
    Molecules, 2022
  • Antidiarrheal and Antibacterial Activities of Monterey Cypress Phytochemicals: In Vivo and In Vitro Approach
    Elshaymaa I. Elmongy, Walaa A. Negm, Engy Elekhnawy, Thanaa A. El-Masry, Nashwah G. M. Attallah, et al.
    Molecules, 2022
  • Combination Treatment of Omega-3 Fatty Acids and Vitamin C Exhibited Promising Therapeutic Effect against Oxidative Impairment of the Liver in Methotrexate-Intoxicated Mice
    Mohammed Alorabi, Doha Saad Mohammed, Gomaa Mostafa-Hedeab, Suzy A. El-Sherbeni, Walaa A. Negm, et al.
    Biomed Research International, 2022
  • Antibacterial, immunomodulatory, and lung protective effects of boswellia dalzielii oleoresin ethanol extract in pulmonary diseases: In vitro and in vivo studies
    Badriyah Alotaibi, Walaa A. Negm, Engy Elekhnawy, Thanaa A. El-Masry, Walaa S. Elseady, et al.
    Antibiotics, 2021
  • Elucidation of phytochemical content of cupressus macrocarpa leaves: In vitro and in vivo antibacterial effect against methicillin-resistant Staphylococcus aureus clinical isolates
    Nashwah G. M. Attallah, Walaa A. Negm, Engy Elekhnawy, Elshaymaa I. Elmongy, Najla Altwaijry, et al.
    Antibiotics, 2021
  • Myricitrin from Physalis pubescensL. leaves and frankincense decrease resistance of MCF-7 cells and ameliorate efficacy of epirubicin
    Suzy Abd El-Hakeem El-Sherbeni, Ghada Mohammad Al-Ashmawy
    Journal of Pharmacy and Pharmacognosy Research, 2021
  • Protective effect of Cupressus macrocarpa and Dioon edule against gentamicin-induced nephrotoxicity in rats
    Journal of Pharmacy and Pharmacognosy Research, 2020
  • A new clerodane diterpene, flavonoids and sterols from Cassia nodosa growing in Egypt: Anti-inflammatory activity of plant extracts
    Journal of Pharmaceutical Sciences and Research, 2015

RECENT SCHOLAR PUBLICATIONS

  • Anti-ulcer and Antibiofilm Activities of Abelmoschus esculentus L. Leaves: Biological and In-Silico Insights
    HI Ghanem, SA El-Sherbeni, AR Azzam, E Elekhnawy, HO Tawfik, ...
    Journal of Advanced Medical and Pharmaceutical Research, 26-37 , 2026
    2026
  • Comparative Preliminary Phytochemical and Biological Investigations on Encephalartos kisambo Faden & Beentje and Encephalartos ferox G. Bertol. Cultivated in Egypt
    SS El-Far, SA El-Sherbeni, AE Ragab, SM Ibrahim
    Journal of Advanced Medical and Pharmaceutical Research, 118-126 , 2025
    2025
  • Phytochemicals of Vitis vinifera L. var. King Ruby protect mice from benzo(a)pyrene-induced lung injury
    GS Ahmedy, HM Selim, M El-Aasr, SM Ibrahim, SA El-Sherbeni
    Scientific Reports 15 (1), 4536 , 2025
    2025
    Citations: 1
  • A Comparative Study of Cytotoxic Effect in Three Vitis vinifera L. Varieties: King Ruby, Thompson and Crimson Against A-549 Lung Cancer Cell Line
    GS Ahmedy, SA El-Sherbeni, M El-Aasr, SM Ibrahim
    Journal of Advanced Medical and Pharmaceutical Research, 1-9 , 2024
    2024
  • Potential Surviving Effect of Cleome droserifolia Extract against Systemic Staphylococcus aureus Infection: Investigation of the Chemical Content of the Plant
    J Alqahtani, WA Negm, E Elekhnawy, IA Hussein, HS Hassan, AR Alanzi, ...
    Antibiotics 13 (5), 450 , 2024
    2024
    Citations: 8
  • The effects of cholesterol and statins on Parkinson’s neuropathology: a narrative review
    HM Al-Kuraishy, EH Fahad, S Al-Windy, SA El-Sherbeni, WA Negm, ...
    Inflammopharmacology 32 (2), 917-925 , 2024
    2024
    Citations: 25
  • Chemotherapeutic effect of baicalein/epirubicin combination against liver cell carcinoma in-vitro: inducing apoptosis and autophagy
    GM Al-Ashmawy, SAEH El-Sherbeni, DA Ali, MA Abo-Saif
    Toxicology in Vitro 95, 105744 , 2024
    2024
    Citations: 8
  • Outlining the Phytoconstituents of Greek Clover Herb Extract and Assessment of Its Effect against Foodborne Infections Caused by Salmonella typhimurium
    J Alqahtani, WA Negm, E Elekhnawy, MJ Alqahtani, E Moglad, S Ibrahim, ...
    Pharmaceuticals 17 (2), 259 , 2024
    2024
    Citations: 3
  • The wound healing effect of botanicals and pure natural substances used in in vivo models
    WAN SA El-Sherbeni
    Inflammopharmacology 31 (2), 755-72 , 2023
    2023
    Citations: 92
  • In Vitro Antiviral Effect and Potential Neuroprotection of Salvadora persica L. Stem Bark Extract against Lipopolysaccharides-Induced Neuroinflammation in Mice …
    R Binsuwaidan, WA Negm, E Elekhnawy, NGM Attallah, E Ahmed, ...
    Pharmaceuticals 16 (3), 398 , 2023
    2023
    Citations: 3
  • GC-MS Analysis of Bioactive Compounds of Gardenia thunbergia Thunb. Leaves and Antibiofilm Potential against Staphylococcus aureus Clinical Isolates
    EM EL-Shial, A Kabbash, M El-Aasr, E Elekhnawy, SA El-Sherbeni
    Journal of Advanced Medical and Pharmaceutical Research 4 (1), 11-18 , 2023
    2023
    Citations: 2
  • A perspective study of the possible impact of obeticholic acid against SARS-CoV-2 infection
    GES Batiha, HM Al-Kuraishy, AI Al-Gareeb, FS Youssef, SA El-Sherbeni, ...
    Inflammopharmacology 31 (1), 9-19 , 2023
    2023
    Citations: 13
  • Elucidation of Natural Components of Gardenia thunbergia Thunb. Leaves: Effect of Methanol Extract and Rutin on Non-Alcoholic Fatty Liver Disease
    EM El-Shial, A Kabbash, M El-Aasr, OA El-Feky, SA El-Sherbeni
    Molecules 28 (2), 879 , 2023
    2023
    Citations: 19
  • Assessment of drugs administered in the Middle East as part of the COVID-19 management protocols
    E Elekhnawy, WA Negm, SA El-Sherbeni, A Zayed
    Inflammopharmacology 30 (6), 1935-1954 , 2022
    2022
    Citations: 5
  • Bilosomes as nanoplatform for oral delivery and modulated in vivo antimicrobial activity of lycopene
    R Binsuwaidan, AA Sultan, WA Negm, NGM Attallah, MJ Alqahtani, ...
    Pharmaceuticals 15 (9), 1043 , 2022
    2022
    Citations: 62
  • Baicalein 5, 6, 7-trimethyl ether from Physalis pubescens L. leaves ameliorate the effect of epirubicin in HepG2 cancer cells by inducing apoptosis and autophagy
    G Al-Ashmawy, M Abo-Saif, S El-Sherbeni
    2022
  • Combination Treatment of Omega-3 Fatty Acids and Vitamin C Exhibited Promising Therapeutic Effect against Oxidative Impairment of the Liver in Methotrexate-Intoxicated Mice
    CACJ Mohammed Alorabi 1, Doha Saad Mohammed 2, Gomaa Mostafa-Hedeab 3 4 ...
    BioMed Research International 2022 , 2022
    2022
    Citations: 29
  • Elucidation of the Metabolite Profile of Yucca gigantea and Assessment of Its Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities
    NGM Attallah, SA El-Sherbeni, AH El-Kadem, E Elekhnawy, TA El-Masry, ...
    Molecules 27 (4), 1329 , 2022
    2022
    Citations: 68
  • Antidiarrheal and antibacterial activities of Monterey cypress phytochemicals: in vivo and in vitro approach
    EI Elmongy, WA Negm, E Elekhnawy, TA El-Masry, NGM Attallah, ...
    Molecules 27 (2), 346 , 2022
    2022
    Citations: 50
  • Antibacterial, Immunomodulatory, and Lung Protective Effects of Boswellia dalzielii Oleoresin Ethanol Extract in Pulmonary Diseases: In Vitro and In Vivo Studies
    B Alotaibi, WA Negm, E Elekhnawy, TA El-Masry, WS Elseady, A Saleh, ...
    Antibiotics 10 (12), 1444 , 2021
    2021
    Citations: 51

MOST CITED SCHOLAR PUBLICATIONS

  • The wound healing effect of botanicals and pure natural substances used in in vivo models
    WAN SA El-Sherbeni
    Inflammopharmacology 31 (2), 755-72 , 2023
    2023
    Citations: 92
  • Elucidation of the Metabolite Profile of Yucca gigantea and Assessment of Its Cytotoxic, Antimicrobial, and Anti-Inflammatory Activities
    NGM Attallah, SA El-Sherbeni, AH El-Kadem, E Elekhnawy, TA El-Masry, ...
    Molecules 27 (4), 1329 , 2022
    2022
    Citations: 68
  • Bilosomes as nanoplatform for oral delivery and modulated in vivo antimicrobial activity of lycopene
    R Binsuwaidan, AA Sultan, WA Negm, NGM Attallah, MJ Alqahtani, ...
    Pharmaceuticals 15 (9), 1043 , 2022
    2022
    Citations: 62
  • Antibacterial, Immunomodulatory, and Lung Protective Effects of Boswellia dalzielii Oleoresin Ethanol Extract in Pulmonary Diseases: In Vitro and In Vivo Studies
    B Alotaibi, WA Negm, E Elekhnawy, TA El-Masry, WS Elseady, A Saleh, ...
    Antibiotics 10 (12), 1444 , 2021
    2021
    Citations: 51
  • Antidiarrheal and antibacterial activities of Monterey cypress phytochemicals: in vivo and in vitro approach
    EI Elmongy, WA Negm, E Elekhnawy, TA El-Masry, NGM Attallah, ...
    Molecules 27 (2), 346 , 2022
    2022
    Citations: 50
  • Elucidation of phytochemical content of Cupressus macrocarpa leaves: in vitro and in vivo antibacterial effect against methicillin-resistant Staphylococcus aureus clinical isolates
    NGM Attallah, WA Negm, E Elekhnawy, EI Elmongy, N Altwaijry, ...
    Antibiotics 10 (8), 890 , 2021
    2021
    Citations: 48
  • Combination Treatment of Omega-3 Fatty Acids and Vitamin C Exhibited Promising Therapeutic Effect against Oxidative Impairment of the Liver in Methotrexate-Intoxicated Mice
    CACJ Mohammed Alorabi 1, Doha Saad Mohammed 2, Gomaa Mostafa-Hedeab 3 4 ...
    BioMed Research International 2022 , 2022
    2022
    Citations: 29
  • The effects of cholesterol and statins on Parkinson’s neuropathology: a narrative review
    HM Al-Kuraishy, EH Fahad, S Al-Windy, SA El-Sherbeni, WA Negm, ...
    Inflammopharmacology 32 (2), 917-925 , 2024
    2024
    Citations: 25
  • Elucidation of Natural Components of Gardenia thunbergia Thunb. Leaves: Effect of Methanol Extract and Rutin on Non-Alcoholic Fatty Liver Disease
    EM El-Shial, A Kabbash, M El-Aasr, OA El-Feky, SA El-Sherbeni
    Molecules 28 (2), 879 , 2023
    2023
    Citations: 19
  • A perspective study of the possible impact of obeticholic acid against SARS-CoV-2 infection
    GES Batiha, HM Al-Kuraishy, AI Al-Gareeb, FS Youssef, SA El-Sherbeni, ...
    Inflammopharmacology 31 (1), 9-19 , 2023
    2023
    Citations: 13
  • Anti-oxidant and cytotoxic activities of Cassia nodosa Buch.-Ham. ex Roxb. and some of its pure constituents
    SA El-Sherbeni, SMI Moustafa, ARS Ibrahim, KAE Seoud, FA Badria
    Afr. J. Pharm. Pharmacol 8, 586-597 , 2014
    2014
    Citations: 11
  • Potential Surviving Effect of Cleome droserifolia Extract against Systemic Staphylococcus aureus Infection: Investigation of the Chemical Content of the Plant
    J Alqahtani, WA Negm, E Elekhnawy, IA Hussein, HS Hassan, AR Alanzi, ...
    Antibiotics 13 (5), 450 , 2024
    2024
    Citations: 8
  • Chemotherapeutic effect of baicalein/epirubicin combination against liver cell carcinoma in-vitro: inducing apoptosis and autophagy
    GM Al-Ashmawy, SAEH El-Sherbeni, DA Ali, MA Abo-Saif
    Toxicology in Vitro 95, 105744 , 2024
    2024
    Citations: 8
  • Protective effect of Cupressus macrocarpa and Dioon edule against gentamicin-induced nephrotoxicity in rats
    GM Al-Ashmawy, SA El-Sherbeni
    J. Pharm. Pharmacogn. Res 8, 434-448 , 2020
    2020
    Citations: 8
  • Myricitrin from Physalis pubescens L. leaves and frankincense decrease resistance of MCF-7 cells and ameliorate efficacy of epirubicin
    S El-Sherbeni, GM Al-Ashmawy
    J. Pharm. Pharmacogn. Res 9, 497-508 , 2021
    2021
    Citations: 6
  • Assessment of drugs administered in the Middle East as part of the COVID-19 management protocols
    E Elekhnawy, WA Negm, SA El-Sherbeni, A Zayed
    Inflammopharmacology 30 (6), 1935-1954 , 2022
    2022
    Citations: 5
  • Elucidation of phytochemical content of Cupressus macrocarpa leaves: in vitro and in vivo antibacterial effect against methicillin-resistant Staphylococcus aureus clinical …
    N Attallah, WA Negm, E Elekhnawy, EI Elmongy, N Altwaijry, H El-Haroun, ...
    2021
    Citations: 5
  • Assessment of renoprotective effect of Physalis pubescens L. & Plumeria acutifolia Poir: flavonoids from P. pubescens L. leaves
    SAEH El-Sherbeni, GM Al-Ashmawy
    Journal of Pharmaceutical Sciences and Research 12 (1), 138-146 , 2020
    2020
    Citations: 4
  • Outlining the Phytoconstituents of Greek Clover Herb Extract and Assessment of Its Effect against Foodborne Infections Caused by Salmonella typhimurium
    J Alqahtani, WA Negm, E Elekhnawy, MJ Alqahtani, E Moglad, S Ibrahim, ...
    Pharmaceuticals 17 (2), 259 , 2024
    2024
    Citations: 3
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