Gamal Mohamed El Maghraby

Scopus Publications

Soft and solid lipid-based nanostructures for dermal and transdermal drug delivery
Gamal M. El Maghraby, Noha D. Fayed
Journal of Drug Delivery Science and Technology, 2026
Dry co-processing of Velpatasvir for Enhancing its Pharmaceutical and Biopharmaceutical Properties
Shaimaa S. Mahmoud, Gamal M. El Maghraby, Ahmed A. Donia, Taher M. Yassin, Shimaa M. Ashmawy
Journal of Pharmaceutical Innovation, 2026
Retraction notice to “Chitosan coated nanostructured lipid carriers for enhanced in vivo efficacy of albendazole against Trichinella spiralis”(Carbohydrate Polymers, (2020), 232, C, (115826), (S0144861719314948), 10.1016/j.carbpol.2019.115826)
Rania K. Eid, Dalia S. Ashour, Ebtessam A. Essa, Gamal M. El Maghraby, Mona F. Arafa
Carbohydrate Polymers, 2026
Niosomes in nanofibers for ocular delivery of nimodipine
Mirna A. Marouf, Mona F. Arafa, El-Refaie Kenawy, Tarek B. Edries, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2026
Development of In Situ Gelling Liquid Extended Release System for Oral Delivery of Abiraterone Acetate
Mohamed M. Shehata, Mona F. Arafa, Ahmed E. Goda, Gamal M. El Maghraby
AAPS Pharmscitech, 2026
Abiraterone acetate (ABA) belongs to low permeability low solubility class. It exhibits pH-dependent solubility with slightly better solubility at gastric pH. It may thus undergo supersaturation and precipitation after gastric emptying. ABA may undergo premature hydrolysis in intestinal lumen which decreases the amount absorbed. This can contribute to its low bioavailability. The aim was to formulate ABA in self-emulsifying drug delivery system (SEDDS), which was loaded in in situ gelling system made of alginate or alginate and chitosan. This can provide controlled release of ABA, preventing possible precipitation with SEDDS augmenting absorption. Alginate and alginate-chitosan based formulations were developed based on gelling capacity. SEDDS comprising oleic acid with Tween 80 and glycerol was fabricated and loaded into in situ gelling formulations. The release behavior was monitored using continuous pH variation. The oral bioavailability of ABA was assessed indirectly by monitoring rat total serum testosterone level. Results indicated that both increasing the concentration of alginate and adding chitosan contributed to enhanced gelation. Loading ABA in SEDDS hastened its dissolution. Loading into in situ gelling system resulted in controlled release with alginate-chitosan system showing better retention of ABA in stomach and intestinal phases. The total serum testosterone level was 8.18, 3.43, 1.51, 3.4 and 0.25 ng/ml for control rat, rats receiving ABA aqueous suspension, ABA in SEDDS, ABA SEDDS in 1% alginate and ABA SEDDS in 1% alginate/1% chitosan. The results suggested that SEDDS can prevent premature degradation and controlling the release within the stomach and intestine maximize the efficacy. Graphical Abstract
Menthol-based self microemulsifying drug delivery system for augmented intestinal absorption of edoxaban
Ola A Refaey, Gamal M El Maghraby, Mona F Arafa, Heba I Elagamy
Journal of Pharmacy and Pharmacology, 2026
Background Clinical effectiveness of edoxaban is hindered by poor solubility and limited permeability due to P-glycoprotein (P-gp) efflux. Aim The aim was to hasten dissolution and intestinal permeability of edoxaban by loading into microemulsion system consisting of menthol as oil and inhibitor of P-gp. Methods Pseudo-ternary phase diagram was constructed at 37°C and microemulsion comprising menthol, tween 80, ethanol and water at ratio of 20:30:30:20 was selected and evaluated. Results Microemulsion’s droplet size was 163.47 nm, its polydispersity index was 0.28, and its zeta potential was −16.43 mV. Edoxaban was loaded in water-free system for dissolution testing. This system underwent self microemulsification in dissolution medium to increase dissolution efficiency to 95.39%, compared with 66.64% for unprocessed edoxaban. Stability assessments demonstrated the system’s stability against various stress conditions. In situ intestinal perfusion studies indicated improved permeability, with 2.96-fold increase in the duodenum and 2.06-fold increase in the ileum compared with edoxaban in aqueous solution. This enhanced absorption was attributed to inhibition of P-gp-mediated efflux by menthol and Tween 80, as well as increased membrane fluidity and permeability. Conclusion These encouraging outcomes highlight the potential of microemulsion in improving both solubility and intestinal permeability of edoxaban enhancing of its oral bioavailability and therapeutic effectiveness.
Capryol-ethyl oleate self-microemulsifying system for improved intestinal absorption and hypoglycemic activity of empagliflozin
Eglal M. Hathout, Suleiman S. Eltokhy, Dalia H. Abdelkader, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2026
Efficacy of Nd: YAG laser versus photodynamic therapy using combination of 5 aminolevulinic acid and intense pulsed light in the treatment of nail psoriasis randomized controlled trial with a split-body design
Samah A. Eldelee, Yomna Mazid El-Hamd Neinaa, Gamal M. El Maghraby, Wael Hussein Mahmoud, El-Sayed Shaaban Hewedy
Journal of the American Academy of Dermatology, 2026
Temperature-dependent phase transition microemulsions for enhanced transdermal delivery of finasteride and silodosin
Hadir F. Marei, Mona F. Arafa, Gamal M. El Maghraby
Scientific Reports, 2025
Tomographic evaluation of apexogenesis with human treated dentin matrix in young permanent molars: a split-mouth randomized controlled clinical trial
Nora M. Abo Shanady, Nahed A. Abo Hamila, Gamal M. El Maghraby, Rehab F. Ghouraba
BMC Oral Health, 2025
Background The concept of vital pulp therapy (VPT) of immature permanent teeth has evolved in recent years. There has been a great tendency towards investigating new pulp capping materials for perfect imitation for natural dentin-pulp complex formation process and restoring the normal tissue’s characteristics. Therefore, this study aimed to assess the clinical and tomographic outcomes of apexogenesis with human treated dentin matrix (hTDM) compared to mineral trioxide aggregate (MTA). Materials and methods 40 bilateral deep carious young mandibular first permanent molars (FPMs) in 20 healthy children aged between 6 and 8 years old were randomly allocated into 2 groups in which the FPMs treated with hTDM and MTA after pulpotomy procedure. The children were followed up clinically at 3, 6, 12, and 18 months. Tomographic evaluation was performed at baseline and 18-month evaluation period. Results The overall clinical success rate was 100% in both groups. Regarding tomographic evaluation, the mean differences in root length, periapical diameter and area were statistically significant in each individual group but without statistically significant differences between both groups. Conclusion Human TDM hydrogel could be considered a promising pulpotomy agent for immature permanent teeth. Trial registration The current clinical trial was recorded at clinicaltrials.gov, NCT06116695, 27/10/2023, Retrospectively registered.
Enhancement of Lurasidone Hydrochloride Dissolution and Pharmacodynamic Properties Via Co-crystal and Eutectic Formation
Maysa A. Hussien, Sally E. Abu-Risha, Ebtessam A. Essa, Gamal M. El Maghraby, Shimaa M. Ashmawy
Journal of Pharmaceutical Innovation, 2025
Niosomes as a vehicle for excretory/secretory antigens enhance immunization efficacy of Toxoplasma gondii vaccine
Salwa S. Younis, Ghada A. Gamea, Gamal M. El Maghraby, Mona F. Arafa, Rana A. Khalifa, et al.
Experimental Parasitology, 2025
Niosomes for enhanced oral delivery of pioglitazone: In vitro characterization and in vivo evaluation
Aya R Elbasuony, Abdelaziz E Abdelaziz, Eman A Mazyed, Gamal M El Maghraby
Journal of Pharmacy and Pharmacology, 2025
Clinical and radiographic evaluation of apexogenesis with human treated dentin matrix in young permanent molars
Nora M. Abo Shanady, Nahed A. Abo Hamila, Gamal M. El Maghraby, Rehab F. Ghouraba
Tanta Dental Journal, 2025
Nanoemulsion for enhanced absorption and anti-tumor activity of dasatinib
Dina A. Eltahan, Rania K. Eid, Shimaa M. Ashmawy, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2025
Photodynamic Therapy With Liquid Crystal Loaded Methylene Blue in the Treatment of Verruca
Ghada F. R. Hassan, Yasmine S. I. El‐Amawy, Gamal M. El Maghraby, Amany M. Abdel‐Latif
Photodermatology Photoimmunology and Photomedicine, 2025
Water in nigella oil microemulsion for enhanced oral bioavailability of linagliptin
Rania K. Eid, Mona F. Arafa, Gamal M. El Maghraby
Drug Delivery and Translational Research, 2025
Hydrotropy and co-crystallization for synergistic enhancement of dissolution rate and in vivo anti-inflammatory efficacy of ebastine
Amal A. Eltobshi, Amal A. Sultan, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2025
Controlled anti-solvent precipitation for enhanced dissolution rate and antiplatelet activity of ticagrelor
Asmaa M. Eldeeb, Dalia H. Abdelkader, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2025
Development of sustained release oral disintegrating tablet of fluvoxamine maleate
Esraa A. Shetaa, Mona F. Arafa, Sally E. Abu-Risha, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2025
Bilosomal Co-Encapsulated Tamoxifen and Propranolol for Potentiated Anti-Breast Cancer Efficacy: In Vitro and In Vivo Investigation
Toka T. Elebyary, Amal A. Sultan, Sally E. Abu-Risha, Gamal M. El Maghraby, Manna Amin
Pharmaceutics, 2025
Preparation of orodispersible tablets of bosentan using xylitol and menthol as dissolution enhancers
Rania Mohamed Sakr, Abdelaziz El Sayed Abdelaziz, Eman Ahmed Mazyed, Gamal Mohamed El Maghraby
Scientific Reports, 2024
Silver nanoparticle with potential antimicrobial and antibiofilm efficiency against multiple drug resistant, extensive drug resistant Pseudomonas aeruginosa clinical isolates
Amal M. Abo Kamer, Gamal M. El Maghraby, Maha Mohamed Shafik, Lamiaa A. Al-Madboly
BMC Microbiology, 2024
Glyceroniosomes for enhanced intestinal absorption of hydrochlorothiazide and lisinopril in their fixed dose combination
Aya R. Elbasuony, Abdelaziz E. Abdelaziz, Eman A. Mazyed, Gamal M. El Maghraby
Scientific Reports, 2024
Bilosomes and Niosomes for Enhanced Intestinal Absorption and In Vivo Efficacy of Cytarabine in Treatment of Acute Myeloid Leukemia
Abdelrahman R. Said, Mona F. Arafa, Walaa A. El-Dakroury, Sultan Alshehri, Gamal M. El Maghraby
Pharmaceuticals, 2024
Eudragit S100 coated surfactant vesicles for boosted oral bioavailability of ticagrelor
Hadir F. Marei, Mona F. Arafa, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2024
Intestinal Absorption Site-Guided Development and Evaluation of Oral Disintegrating Controlled Release Tablets of Mirabegron
Mohammed I. Ghanem, Shimaa M. Ashmawy, Gamal M. El Maghraby
AAPS Pharmscitech, 2024
Cinnamon oil-based self-emulsifying system for augmented dissolution and hypoglycemic efficacy of gliquidone
Mohamed El-Araby, Sanaa A. El-Gizawy, Shimaa M. Ashmawy, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2024
Chitosan coated lipid carriers as nanoplatform for repurposed anti-breast cancer activity of niclosamide
Nancy E. Elkholy, Amal A. Sultan, Sally E. Abu-Risha, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2024
Olive oil and flaxseed oil incorporating niosomes for enhanced in vivo anti-diabetic efficacy of canagliflozin
Ghada Saad, Gamal M. El Maghraby, Amal A. Sultan
Drug Development and Industrial Pharmacy, 2024
Combined eutexia and amorphization for simultaneous enhancement of dissolution rate of triamterene and hydrochlorothiazide: preparation of orodispersible tablets
Hend A. Awad, Mohamed I. Fetouh, Amal A. Sultan, Gamal M. El Maghraby
Drug Development and Industrial Pharmacy, 2024
Surfactant nanovesicles for augmented antibacterial activity against carbapenemase resistant enterobacteriaceae and extended spectrum beta-lactamases producing bacteria: in vitro and in vivo evaluation
Amal M. Abo Kamer, Noha M. Amer, Ahmed A. Abdelmegeed, Gamal M. El Maghraby, Noha M. Gamaleldin
BMC Microbiology, 2023
Efficacy of prostaglandin E2 versus prostaglandin F2 alpha assisted with narrowband-UVB in stable vitiligo
Yomna Mazid El-Hamd Neinaa, Myada Abd Elmohsen Mahmoud, Gamal Mohamed El Maghraby, Zeinab Abd Elsamd Ibrahim
Archives of Dermatological Research, 2023
Hot melt extrusion for enhanced dissolution and intestinal absorption of hydrochlorothiazide
Ebtessam Essa, Manna Amin, Amal Sultan, Mona Arafa, Gamal El Maghraby, et al.
Journal of Drug Delivery Science and Technology, 2023
Co-processing of fluconazole with menthol for enhanced dissolution and anti-fungal activity: Preparation of orodispersable tablets
Asmaa M. El Shiekh Ali, Gamal M. El Maghraby, Abdelaziz E. Abdelaziz, Ahmed M. Soliman, Eman M. Saied, et al.
Journal of Drug Delivery Science and Technology, 2023
Melt granulation for Enhanced Dissolution Rate and Antimicrobial activity of Cefpodoxime Proxetil
Nouran Abdel Kader, Amal Abo Kamer, Engy Elekhnawy, Mona Arafa, Ebtessam A Essa, et al.
Research Journal of Pharmacy and Technology, 2023
Efficacy and Safety of Topical Tranexamic Acid Alone or in Combination with Either Fractional Carbon Dioxide Laser or Microneedling for the Treatment of Melasma
Safaa Mamdouh Kamal, Doaa Salah Hegab, Gamal Mohamed El Maghraby, Amal Ahmad El- Ashmawy
Dermatology Practical and Conceptual, 2023
Surfactant vesicles for enhanced antitoxoplasmic effect of norfloxacin: In vitro and in vivo evaluations
Rania K. Eid, Mona F. Arafa, Dalia S. Ashour, Ebtessam A. Essa, Eman S. El-Wakil, et al.
International Journal of Pharmaceutics, 2023
Investigation of the effect of concurrently administered carvedilol, atorvastatin and bile salts on intestinal absorption of linagliptin
Muhammad A Embaby, Gamal M El Maghraby, Mohamed A Osman, Amal A Sultan
Journal of Pharmacy and Pharmacology, 2023
Novel insights on the therapeutic effect of levamisole on the chronic toxoplasmosis in mice model
Hager S. Zoghroban, Basma M. Elmansory, Yasmine Amr Issa, Amira K. Eltokhy, Hend S. Abo Safia, et al.
Experimental Parasitology, 2023
Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing mice
Amr Zidan, Amira A. EL Saadany, Gamal M. El Maghraby, Amany A. Abdin, Sabeha E. Hedya
Toxicology and Applied Pharmacology, 2023
Mefloquine loaded niosomes as a promising approach for the treatment of acute and chronic toxoplasmosis
Basma M. El Sharazly, Ibrahim A. Aboul Asaad, Nabila A. Yassen, Gamal M. El Maghraby, Wayne G. Carter, et al.
Acta Tropica, 2023
Permeation enhancers loaded bilosomes for improved intestinal absorption and cytotoxic activity of doxorubicin
Amal A. Sultan, Ghada A. Saad, Gamal M. El Maghraby
International Journal of Pharmaceutics, 2023
Skin ceramides based systems in transdermal drug delivery and skin care
Gamal M. El Maghraby, Mona F. Arafa
Green Sustainable Process for Chemical and Environmental Engineering and Science Biomedical Applications of Green Composites, 2023
Co-Crystallization of Sofosbuvir with Sugars for Enhanced Dissolution Rate
Taher Mohamed Yassen Mousa, Ahmed Atef Donia, Gamal Mohamed El Maghraby
Indonesian Journal of Pharmacy, 2023
Eutectic phase transition during tablet manufacture: effect of melting point of eutectic forming drug
Hadir F. Marei, Gamal M. El Maghraby, Mona F. Arafa
Pharmaceutical Development and Technology, 2023
Self-emulsifying systems for drug delivery: advances and challenges
Gamal M. El Maghraby, Mona F. Arafa, Amal A. Sultan
Advanced and Modern Approaches for Drug Delivery, 2023
L-Proline as Co-Crystal Forming Amino Acid for Enhanced Dissolution Rate of Lamotrigine: Development of Oral Dispersible Tablet
Howaida Abdelrahman, Ebtesam Essa, Gamal El Maghraby, Mona Arafa
Indonesian Journal of Pharmacy, 2023
The Development and Evaluation of Phase Transition Microemulsion for Ocular Delivery of Acetazolamide for Glaucoma Treatment
Lubna M. Abd El Wahab, Ebtessam A. Essa, Gamal M. El Maghraby, Mona F. Arafa
AAPS Pharmscitech, 2023
Melting point depression for enhanced dissolution rate of eslicarbazepine acetate
Ebtehal M. Dorgham, Gamal M. El Maghraby, Ebtessam A. Essa, Mona F. Arafa
Drug Development and Industrial Pharmacy, 2023
Modulating Nimodipine Crystallinity for Enhancing Dissolution: Development of Geriatric-Friendly Dosage Form
Howaida Abdelrahman, Ebtessam Essa, Gamal El Maghraby, Mona Farouk Arafa
Pharmaceutical Sciences, 2022
Lopinavir-menthol co-crystals for enhanced dissolution rate and intestinal absorption
Noha D. Fayed, Mona F. Arafa, Ebtesam A. Essa, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2022
Eudragit coated microemulsion for enhanced efficacy of spiramycin against toxoplasmic encephalitis
Rania K. Eid, Mona F. Arafa, Dalia S. Ashour, Ebtessam A. Essa, Hager S. Zoghroban, et al.
Journal of Drug Delivery Science and Technology, 2022
Menthol augmented niosomes for enhanced intestinal absorption of lopinavir
Noha D. Fayed, Ebtesam A. Essa, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2022
Self-dispersing self-assembling systems for controlled oral delivery of gliclazide
Nourhan F. El Nashar, Amal A. Sultan, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2021
Chitosan-encapsulated niosomes for enhanced oral delivery of atorvastatin
Noha D. Fayed, Ahmed E. Goda, Ebtesam A. Essa, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2021
Microsponges for controlled release and enhanced oral bioavailability of carbamazepine
Karam F. Abdalla, Mohamed A. Osman, Ahmed T. Nouh, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2021
Enhanced Efficacy of Some Antibiotics in Presence of Silver Nanoparticles Against Multidrug Resistant Pseudomonas aeruginosa Recovered From Burn Wound Infections
Maha A. Khalil, Gamal M. El Maghraby, Fatma I. Sonbol, Nanis G. Allam, Perihan S. Ateya, et al.
Frontiers in Microbiology, 2021
Niosomal versus nano-crystalline ivermectin against different stages of Trichinella spiralis infection in mice
Dalia A. Elmehy, Marwa A. Hasby Saad, Gamal M. El Maghraby, Mona F. Arafa, Nema A. Soliman, et al.
Parasitology Research, 2021
Ocular films versus film-forming liquid systems for enhanced ocular drug delivery
Hamdia G. Wafa, Ebtessam A. Essa, Alaa E. El-Sisi, Gamal M. El Maghraby
Drug Delivery and Translational Research, 2021
Nanographene oxide for enhanced dissolution rate and antibacterial activity of cefdinir
Dina E. Bali, Mona F. Arafa, Noha M. Gamaleldin, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2021
Hydrophilic sugars for enhancing dissolution rate of cilostazol: Effect of wet co-processing
Alaa Yosf Bazeed, Ahmed Nouh, Ebtessam Ahmed Essa, Gamal El Maghraby
Pharmaceutical Sciences, 2021
Co-processing of Atorvastatin and Ezetimibe for Enhanced Dissolution Rate: In Vitro and In Vivo Correlation
Mona F. Arafa, Rasha A. Alshaikh, Magdy M. Abdelquader, Gamal M. El Maghraby
AAPS Pharmscitech, 2021
Lidocaine as eutectic forming drug for enhanced transdermal delivery of nonsteroidal anti-inflammatory drugs
Hadir F. Marei, Mona F. Arafa, Ebtessam A. Essa, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2021
Smart liquids for oral controlled drug release: An overview of alginate and non-alginate based systems
Ebtessam A. Essa, Toka T. Elebyary, Magdy M. Abdelquader, Gamal M. El Maghraby, Amal A. Elkordy
Journal of Drug Delivery Science and Technology, 2021
Ethanol-assisted kneading of apigenin with arginine for enhanced dissolution rate of apigenin: development of rapidly disintegrating tablets
Fatma A. Kassem, Abdelaziz E. Abdelaziz, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2021
Nanostructured lipid carriers for enhanced in vitro and in vivo schistosomicidal activity of praziquantel: effect of charge
Abdelrahman R. Said, Hager S. Zoghroban, Mona F. Arafa, Soheir S. Mahmoud, Gamal M. El Maghraby
Drug Development and Industrial Pharmacy, 2021
Co-processing of nateglinide with meglumine for enhanced dissolution rate: in vitro and in vivo evaluation
Alaa Y. Bazeed, Ebtessam A. Essa, Ahmed Nouh, Gamal M. El Maghraby
Drug Development and Industrial Pharmacy, 2020
Acetone-assisted co-processing of meloxicam with amino acids for enhanced dissolution rate
Nancy E. Elkholy, Amal A. Sultan, Ghada H. Elosaily, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2020
Comparative clinical study of the efficacy of intralesional MMR vaccine vs intralesional vitamin D injection in treatment of warts
Dalia R. Shaldoum, Ghada F. R. Hassan, Eman H. El Maadawy, Gamal M. El‐Maghraby
Journal of Cosmetic Dermatology, 2020
Chitosan coated nanostructured lipid carriers for enhanced in vivo efficacy of albendazole against Trichinella spiralis
Rania K. Eid, Dalia S. Ashour, Ebtessam A. Essa, Gamal M. El Maghraby, Mona F. Arafa
Carbohydrate Polymers, 2020
Preparation of stabilized submicron fenofibrate crystals on niacin as a hydrophilic hydrotropic carrier
Rasha A. Alshaikh, Ebtessam A. Essa, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2020
Liposomes for enhanced cellular uptake of anticancer agents
Gamal M. El Maghraby, Mona F. Arafa
Current Drug Delivery, 2020
Formulation of acyclovir-loaded solid lipid nanoparticles: 2. Brain targeting and pharmacokinetic study
Sanaa A. El-Gizawy, Gamal M. El-Maghraby, Asmaa A. Hedaya
Pharmaceutical Development and Technology, 2019
Formulation of acyclovir-loaded solid lipid nanoparticles: design, optimization, and in-vitro characterization
Sanaa A. El-Gizawy, Gamal M. El-Maghraby, Asmaa A. Hedaya
Pharmaceutical Development and Technology, 2019
Development and evaluation of rapidly dissolving buccal films of naftopidil: in vitro and in vivo evaluation
Heba I. Elagamy, Ebtessam A. Essa, Ahmed Nouh, Gamal M. El Maghraby
Drug Development and Industrial Pharmacy, 2019
Co-crystallization for enhanced dissolution rate of bicalutamide: preparation and evaluation of rapidly disintegrating tablets
Ebtessam A. Essa, Aya R. Elbasuony, Abdelaziz E. Abdelaziz, Gamal M. El Maghraby
Drug Development and Industrial Pharmacy, 2019
Development and evaluation of liquid oral controlled release systems for Losartan potassium
Journal of Applied Pharmaceutical Science, 2019
Eutexia for enhanced dissolution rate and anti-inflammatory activity of nonsteroidal anti-inflammatory agents: Caffeine as a melting point modulator
Rasha A. Alshaikh, Ebtessam A. Essa, Gamal M. El Maghraby
International Journal of Pharmaceutics, 2019
Regional difference in intestinal drug absorption as a measure for the potential effect of P-glycoprotein efflux transporters
Shimaa M Ashmawy, Sanaa A El-Gizawy, Gamal M El Maghraby, Mohamed A Osman
Journal of Pharmacy and Pharmacology, 2019
Essential oils in niosomes for enhanced transdermal delivery of felodipine
Rania K. Eid, Ebtessam A. Essa, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2019
D-glucose elicits significant increase in the oral bioavailability of model BCS class III drugs in the rabbit
Shimaa M. Ashmawy, Mohamed A. Osman, Sanaa A. El-Gizawy, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2019
Niosomes for enhanced activity of praziquantel against Schistosoma mansoni: in vivo and in vitro evaluation
Hager S. Zoghroban, Samy I. El-Kowrany, Ibrahim A. Aboul Asaad, Gamal M. El Maghraby, Kholoud A. El-Nouby, et al.
Parasitology Research, 2019
Alginate-chitosan combinations in controlled drug delivery
Gamal M. El Maghraby, Mona F. Arafa
Natural Polysaccharides in Drug Delivery and Biomedical Applications, 2019
Inhibition of Co-Crystallization of Olmesartan Medoxomil and Hydrochlorothiazide for Enhanced Dissolution Rate in Their Fixed Dose Combination
Magdy M. Abdelquader, Ebtessam A. Essa, Gamal M. El Maghraby
AAPS Pharmscitech, 2019
Optimization of eugenol microemulsion for transdermal delivery of indomethacin
Noha W. El Khayat, Ahmed A. Donia, Omer Y. Mady, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2018
A comparative study between two topical treatments (tranexamic acid and flutamide) in the treatment of patients with melasma
Arwa M. Hassan, Ghada F.R. Hassan, Mayada A.F. Ismail, Gamal M. El-Maghraby
Journal of the Egyptian Women S Dermatologic Society, 2018
Niosomes for oral delivery of nateglinide: in situ–in vivo correlation
Amal A. Sultan, Sanaa A. El-Gizawy, Mohamed A. Osman, Gamal M. El Maghraby
Journal of Liposome Research, 2018
Phase transition microemulsions as drug delivery systems
Gamal M. El Maghraby, Mona F. Arafa, Ebtessam A. Essa
Applications of Nanocomposite Materials in Drug Delivery, 2018
Vesicular nanostructures for transdermal delivery
Gamal M. El Maghraby, Mona F. Arafa, Ebtessam A. Essa
Applications of Nanocomposite Materials in Drug Delivery, 2018
Xylitol as a potential co-crystal co-former for enhancing dissolution rate of felodipine: preparation and evaluation of sublingual tablets
Mona F. Arafa, Sanaa A. El-Gizawy, Mohamed A. Osman, Gamal M. El Maghraby
Pharmaceutical Development and Technology, 2018
Effect of neat and binary vehicle systems on the solubility and cutaneous delivery of piperine
Abdullah Hasan Alomrani, Faisal Ibraheem Alhazza, Khalid Mohammed AlGhamdi, Gamal Mohamed El Maghraby
Saudi Pharmaceutical Journal, 2018
Efficacy of topical latanoprost versus minoxidil and betamethasone valerate on the treatment of alopecia areata
Amal Ahmad El-Ashmawy, Iman Hamed El-Maadawy, Gamal Mohamed El-Maghraby
Journal of Dermatological Treatment, 2018
Peceosomes for oral delivery of glibenclamide: In vitro in situ correlation
Amal A. Sultan, Sanaa A. El-Gizawy, Mohamed A. Osman, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2017
Formulation of clarithromycin floating microspheres for eradication of Helicobacter pylori
Nourhan F. El Nashar, Ahmed A. Donia, Omar Y. Mady, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2017
Controlled precipitation for enhanced dissolution rate of flurbiprofen: development of rapidly disintegrating tablets
Ebtessam A. Essa, Amira O. Elmarakby, Ahmed M. A. Donia, Gamal M. El Maghraby
Drug Development and Industrial Pharmacy, 2017
Occlusive versus nonocclusive application in transdermal drug delivery
Gamal M. El Maghraby
Percutaneous Penetration Enhancers Drug Penetration into Through the Skin Methodology and General Considerations, 2017
Co-crystallization for enhanced dissolution rate of nateglinide: In vitro and in vivo evaluation
Mona F. Arafa, Sanaa A. El-Gizawy, Mohamed A. Osman, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2017
Self dispersing mixed micelles forming systems for enhanced dissolution and intestinal permeability of hydrochlorothiazide
Amal A. Sultan, Sanaa A. El-Gizawy, Mohamed A. Osman, Gamal M. El Maghraby
Colloids and Surfaces B Biointerfaces, 2017
Enhancement of Dissolution Rate and Intestinal Stability of Clopidogrel Hydrogen Sulfate
Dina E. Bali, Mohamed A. Osman, Gamal M. El Maghraby
European Journal of Drug Metabolism and Pharmacokinetics, 2016
Enhancement of dissolution rate and intestinal stability of candesartan cilexitil
Noha Fayed, Mohamed Osman, Gamal Maghraby
Journal of Applied Pharmaceutical Science, 2016
Transdermal delivery of kojic acid from microemulgel
Mahmoud Nagar, Mahmoud Mahdy, Mohamed Selem, Gamal Maghraby
Journal of Applied Pharmaceutical Science, 2016
Colloidal carriers for extended absorption window of furosemide
Amal A Sultan, Sanaa A El-Gizawy, Mohamed A Osman, Gamal M El Maghraby
Journal of Pharmacy and Pharmacology, 2016
Preparation and evaluation of rapidly dissolving tablets of raloxifene hydrochloride by ternary system formation
International Journal of Pharmacy and Pharmaceutical Sciences, 2016
Self microemulsefying and non-self microemulsefying liquisolid tablet of felodipine
Gehad Khorshed, Gamal El-Maghraby
Journal of Applied Pharmaceutical Science, 2016
Enhancement of dissolution rate of hydrochlorothiazide
International Journal of Pharmacy and Pharmaceutical Sciences, 2016
Development of liquid oral sustained release formulations of nateglinide: In vitro and in vivo evaluation
Gamal M. El Maghraby, Alaa E. Elsisi, Gehad A. Elmeshad
Journal of Drug Delivery Science and Technology, 2015
Effects of Nigella sativa, Lepidium sativum and Trigonella foenum-graecum on sildenafil disposition in beagle dogs
Abdullah M. Al-Mohizea, Abdul Ahad, Gamal M. El-Maghraby, Fahad I. Al-Jenoobi, Khalid M. AlKharfy, et al.
European Journal of Drug Metabolism and Pharmacokinetics, 2015
Development and evaluation of glibenclamide floating tablet with optimum release
Ebtessam A. Essa, Fatma E. Elkotb, Esmat E. Zin Eldin, Gamal M. El Maghraby
Journal of Drug Delivery Science and Technology, 2015
Evaluation of the efficacy and safety of combinations of hydroquinone, glycolic acid, and hyaluronic acid in the treatment of melasma
Zeinab A Ibrahim, Shereen F Gheida, Gamal M El Maghraby, Zeinab E Farag
Journal of Cosmetic Dermatology, 2015
Transdermal Delivery of Nisoldipine: Refinement of Vehicles
International Journal of Pharmaceutical Compounding, 2015
Optimization of niosomes for enhanced antibacterial activity and reduced bacterial resistance: In vitro and in vivo evaluation
Ahmed A Abdelaziz, Tarek E Elbanna, Fatma I Sonbol, Noha M Gamaleldin, Gamal M El Maghraby
Expert Opinion on Drug Delivery, 2015
Aerosil as a novel co-crystal co-former for improving the dissolution rate of hydrochlorothiazide
Sanaa A. El-Gizawy, Mohamed A. Osman, Mona F. Arafa, Gamal M. El Maghraby
International Journal of Pharmaceutics, 2015
Formulation and evaluation of simvastatin buccal film
Gamal El-Maghraby, Mona Abdelzaher
Journal of Applied Pharmaceutical Science, 2015
Natural and synthetic oil phase transition microemulsions for ocular delivery of tropicamide: Efficacy and safety
Heba I El Agamy, Gamal M El Maghraby
Journal of Applied Pharmaceutical Science, 2015
Optimization of the entrapment efficiency and release of ambroxol hydrochloride alginate beads
Karam Abdalla, Elabadawy Kamoun, Gamal Maghraby
Journal of Applied Pharmaceutical Science, 2015
Penetration enhancers in proniosomes as a new strategy for enhanced transdermal drug delivery
Gamal M. El Maghraby, Amal A. Ahmed, Mohamed A. Osman
Saudi Pharmaceutical Journal, 2015
Sucralose as co-crystal co-former for hydrochlorothiazide: Development of oral disintegrating tablets
Mona F. Arafa, Sanaa A. El-Gizawy, Mohamed A. Osman, Gamal M. El Maghraby
Drug Development and Industrial Pharmacy, 2015
Cyclodextrins enhances the intestinal permeability of P-glycoprotein substrate
Latin American Journal of Pharmacy, 2015
Microemulsion for simultaneous transdermal delivery of benzocaine and indomethacin: In vitro and in vivo evaluation
Gamal M. El Maghraby, Mona F. Arafa, Mohamed A. Osman
Drug Development and Industrial Pharmacy, 2014
Effect of pharmaceutical excipients on the permeability of P-glycoprotein substrate
A.M. Al-Mohizea, F. Zawaneh, M.A. Alam, F.I. Al-Jenoobi, G.M. El-Maghraby
Journal of Drug Delivery Science and Technology, 2014
Fast disintegrating tablets of nisoldipine for intra-oral administration
Gamal M. El Maghraby, Ramy N. Elsergany
Pharmaceutical Development and Technology, 2014
Skin delivery of nisoldipine from niosome proconcentrate
Gamal M. El Maghraby, Amal A. Ahmed, Mohamed A. Osman
Journal of Applied Pharmaceutical Science, 2014
Self emulsifying liquisolid tablets for enhanced oral bioavailability of repaglinide: In vitro and in vivo evaluation
Journal of Applied Pharmaceutical Science, 2014
Formulation and evaluation of a colon drug delivery system containing Diflunisal
Esmat Zein El Din, Gamal El Maghraby, Ahmed Donia, Samar Mayah
Bulletin of Pharmaceutical Sciences Assiut, 2014
Evaluation of progesterone permeability from supercritical fluid processed dispersion systems
James R. Falconer, Jingyuan Wen, Sara Zargar-Shoshtari, John J. Chen, Mohammed Farid, et al.
Pharmaceutical Development and Technology, 2014
Clusive and non-occlusive application of microemulsion for transdermal delivery of progesterone: Mechanistic studies
Gamal M. El Maghraby
Scientia Pharmaceutica, 2012
Development of modified in situ gelling oral liquid sustained release formulation of dextromethorphan
Gamal M. El Maghraby, Ehab M. Elzayat, Fars K. Alanazi
Drug Development and Industrial Pharmacy, 2012
Microemulsions as transdermal drug delivery systems
Gamal M. El Maghraby
Current Nanoscience, 2012
Development and validation of an HPLC-UV method for the quantification of carbamazepine in rabbit plasma
Hammam A. Mowafy, Fars K. Alanazi, Gamal M. El Maghraby
Saudi Pharmaceutical Journal, 2012
Effect of binary and ternary solid dispersions on the in vitro dissolution and in-situ rabbit intestinal absorption of gliclazide
Pakistan Journal of Pharmaceutical Sciences, 2011
Design of programmable release formulations for combined therapy
International Journal of Pharmtech Research, 2011
Investigation of self-microemulsifying and microemulsion systems for protection of prednisolone from gamma radiation
Gamal M. El Maghraby, Ahmed A. Bosela
Pharmaceutical Development and Technology, 2011
Liposomes for enhanced cytotoxic activity of bleomycin
Abdullah H. Alomrani, Gamal M. El Maghraby, Fars K. Alanazi, Mai A. Al‐Mohanna, Ayodele A. Alaiya, et al.
Drug Development Research, 2011
Self-microemulsifying and microemulsion systems for transdermal delivery of indomethacin: Effect of phase transition
Gamal M. El Maghraby
Colloids and Surfaces B Biointerfaces, 2010
Vesicular systems for intranasal drug delivery
Ibrahim A. Alsarra, Amel Y. Hamed, Fars K. Alanazi, Gamal M. El Maghraby
Neuromethods, 2010
Effects of hydroxypropyl-β-cyclodextrin, gel and in situ gelling systems on the stability of hydrocortisone after gamma irradiation
G.M. El Maghraby, A.H. Alomrani
Journal of Drug Delivery Science and Technology, 2010
Synergistic enhancement of itraconazole dissolution by ternary system formation with pluronic F68 and hydroxypropylmethylcellulose
Gamal M. El Maghraby
Scientia Pharmaceutica, 2009
Transdermal delivery of tadalafil. I. Effect of vehicles on skin permeation
Gamal M. El Maghraby, Fars Kaed Alanazi, Ibrahim A. Alsarra
Drug Development and Industrial Pharmacy, 2009
Mucoadhesive polymeric hydrogels for nasal delivery of acyclovir
Ibrahim A. Alsarra, Amel Y. Hamed, Gamal M. Mahrous, Gamal M. El Maghraby, Abdulrahman A. Al-Robayan, et al.
Drug Development and Industrial Pharmacy, 2009
Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin
GM El Maghraby, AC Williams
Expert Opinion on Drug Delivery, 2009
Liposomes and skin: From drug delivery to model membranes
G.M. El Maghraby, B.W. Barry, A.C. Williams
European Journal of Pharmaceutical Sciences, 2008
Transdermal delivery of hydrocortisone from eucalyptus oil microemulsion: Effects of cosurfactants
Gamal M. El Maghraby
International Journal of Pharmaceutics, 2008
Phase transition water-in-oil microemulsions as ocular drug delivery systems: In vitro and in vivo evaluation
Judy Chan, Gamal M.M. El Maghraby, Jennifer P. Craig, Raid G. Alany
International Journal of Pharmaceutics, 2007
Can drug-bearing liposomes penetrate intact skin?
Gamal M M El Maghraby, Adrian C Williams, Brian W Barry
Journal of Pharmacy and Pharmacology, 2006
The effect of ciprofloxacin and clarithromycin on sildenafil oral bioavailability in human volunteers
Mohsen A. Hedaya, Dalia R. El-Afify, Gamal M. El-Maghraby
Biopharmaceutics and Drug Disposition, 2006
Intestinal absorption and presystemic disposition of sildenafil citrate in the rabbit: Evidence for site-dependent absorptive clearance
Mohammed A. Osman, Gamal M. El Maghraby, Mohsen A. Hedaya
Biopharmaceutics and Drug Disposition, 2006
Mechanisms of action of novel skin penetration enhancers: Phospholipid versus skin lipid liposomes
Gamal M.M. El Maghraby, Michael Campbell, Barrie C. Finnin
International Journal of Pharmaceutics, 2005
Drug interaction and location in liposomes: Correlation with polar surface areas
G.M.M. El Maghraby, A.C. Williams, B.W. Barry
International Journal of Pharmaceutics, 2005
Interactions of surfactants (edge activators) and skin penetration enhancers with liposomes
G.M.M El Maghraby, A.C Williams, B.W Barry
International Journal of Pharmaceutics, 2004
Skin hydration and possible shunt route penetration in controlled estradiol delivery from ultradeformable and standard liposomes
Gamal M M El Maghraby, Adrian C Williams, Brian W Barry
Journal of Pharmacy and Pharmacology, 2001
Skin delivery of 5-fluorouracil from ultradeformable and standard liposomes in-vitro
Gamal M M El Maghraby, Adrian C Williams, Brian W Barry
Journal of Pharmacy and Pharmacology, 2001
Skin delivery of oestradiol from lipid vesicles: Importance of liposome structure
Gamal M.M El Maghraby, Adrian C Williams, Brian W Barry
International Journal of Pharmaceutics, 2000
Oestradiol skin delivery from ultradeformable liposomes: Refinement of surfactant concentration
Gamal M.M. El Maghraby, Adrian C. Williams, Brian W. Barry
International Journal of Pharmaceutics, 2000
Skin delivery of oestradiol from deformable and traditional liposomes: Mechanistic studies
Gamal M M El Maghraby, Adrian C Williams, Brian W Barry
Journal of Pharmacy and Pharmacology, 1999
Optimization of deformable vesicles for epidermal delivery of oestradiol
G M M el Maghraby, A C Williams, B W Barry
Journal of Pharmacy and Pharmacology, 1998

Gamal Mohamed El Maghraby

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