RECENT SCHOLAR PUBLICATIONS
- Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes ProjectM N Leathlobhair, A Frangou, B Kinnersley, AJ Cornish, D Chubb, ...Nature Communications 15 (1), 9247 2024
- The genomic landscape of 2,023 colorectal cancersAJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ...Nature 633 (8028), 127-136 2024
- Homopolymer switches mediate adaptive mutability in mismatch repair-deficient colorectal cancerH Kayhanian, W Cross, SEM van der Horst, P Barmpoutis, E Lakatos, ...Nature Genetics 56 (7), 1420-1433 2024
- 416P Evolutionary and immune microenvironment dynamics determine response to neoadjuvant treatment of oesophageal adenocarcinomaM Barroux, J Househam, E Lakatos, T Ronel, AM Baker, H Sali, ...Annals of Oncology 35, S168-S169 2024
- 153P Determinants of tumour-immune evolutionary trajectory in colorectal cancerE Lakatos, V Gunasri, L Zapata, J Househam, T Heide, N Trahearn, ...Annals of Oncology 35, S68 2024
- Lower incidence of small intestinal adenocarcinomas may be due to constrained copy number karyotype and increased immune surveillanceS Nowinski, V Balarajah, AM Baker, R Katainen, C Hughes, Q Guo, ...CANCER RESEARCH 84 (3) 2024
- Long deletion signatures in repetitive genomic regions track somatic evolution and enable sensitive detection of microsatellite instabilityQ Guo, J Househam, E Lakatos, S Nowinski, I Al Bakir, H Grant, ...bioRxiv, 2024.10. 03.616572 2024
- Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancerE Lakatos, V Gunasri, L Zapata, J Househam, T Heide, N Trahearn, ...bioRxiv, 2024.02. 12.579956 2024
- Spatially resolving the dynamics of immunoediting in advanced colorectal cancerV Gunasri, N Trahearn, E Lakatos, J Househam, T Heide, GD Cresswell, ...JOURNAL OF PATHOLOGY 261, S29-S29 2023
- O44 Co-evolution of mismatch repair loss and the immune response in Lynch SyndromeO Swinyard, AM Baker, K Monahan, M Jansen, C Gabbutt, C Kimberley, ...Gut 72 (Suppl 2), A25-A26 2023
- 253e IMMUNE EDITING IN THE INVASIVE MARGIN AND NODE DEPOSITS OF COLORECTAL CANCER SELECTS FOR CELLULAR NEIGHBOURHOODS ENRICHED IN PDL1+ CANCER CELLSV Gunasri, E Lakatos, N Trahearn, L Cisneros, J Househam, T Heide, ...Gastroenterology 164 (6), S-1569 2023
- Evolutionary and immune microenvironment dynamics during neoadjuvant treatment of oesophagael adenocarcinomaM Barroux, J Househam, E Lakatos, T Ronel, AM Baker, H Sali, ... 2023
- Tumor evolution and immune microenvironment dynamics define response to neoadjuvant treatment of esophageal adenocarcinomaM Barroux, J Househam, E Lakatos, T Ronel, AM Baker, H Sali, ...Cancer Research 83 (7_Supplement), 4539-4539 2023
- Immune selection determines tumor antigenicity and influences response to checkpoint inhibitorsL Zapata, G Caravagna, MJ Williams, E Lakatos, K AbdulJabbar, ...Nature Genetics 55 (3), 451-460 2023
- Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancerH Hockings, E Lakatos, W Huang, M Mossner, MA Khan, S Metcalf, ...bioRxiv, 2023.07. 21.549688 2023
- Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactionsAJ Cornish, AJ Gruber, B Kinnersley, D Chubb, A Frangou, G Caravagna, ...bioRxiv, 2022.11. 16.515599 2022
- Phenotypic plasticity and genetic control in colorectal cancer evolutionJ Househam, T Heide, GD Cresswell, I Spiteri, C Kimberley, L Zapata, ...Nature, 1-10 2022
- The co-evolution of the genome and epigenome in colorectal cancerT Heide, J Househam, GD Cresswell, I Spiteri, C Lynn, M Mossner, ...Nature, 1-11 2022
- The mutational signatures of formalin fixation on the human genomeQ Guo, E Lakatos, IA Bakir, K Curtius, TA Graham, V MustonenNature communications 13 (1), 1-14 2022
- Abstract B001: Developing adaptive therapy to suppress the evolution of treatment resistance in high-grade serous ovarian cancerH Hockings, M Lockley, T Graham, E Lakatos, W HuangCancer Research 82 (10_Supplement), B001-B001 2022
