Ahmed Waraky

@gu.se

Laboratory medicine
Gothenburg University

RESEARCH, TEACHING, or OTHER INTERESTS

Cancer Research, Molecular Medicine, Biochemistry, Genetics and Molecular Biology

162

Scholar Citations

6

Scholar h-index

5

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Aberrant MNX1 expression associated with t (7; 12)(q36; p13) pediatric acute myeloid leukemia induces the disease through altering histone methylation
    A Waraky, A stlund, T Nilsson, D Weichenhan, P Lutsik, M Bhr, J Hey, ...
    Haematologica 109 (3), 725 2024

  • Altered enhancer-promoter interaction leads to MNX1 expression in pediatric acute myeloid leukemia with t(7;12)(q36;p13)
    D Weichenhan, A Riedel, E Sollier, UH Toprak, J Hey, K Breuer, ...
    bioRxiv, 2023.09. 13.557546 2023

  • 3217–REGULATORY NETWORKS OF HUMAN EXTRAMEDULLARY HEMATOPOIESIS
    A Waraky, H Bastos, N Mende, E Laurenti
    Experimental Hematology 124, S158 2023

  • Mnx1 Induces Leukemia Transformation Through Altering Histone Methylation in a Model of Pediatric Acute Myeloid Leukemia with t (7; 12)(q36; p13)
    A Waraky, A stlund, T Nilsson, D Weichenan, P Lutsik, M Bhr, J Hey, ...
    2022

  • An induced pluripotent stem cell t (7; 12)(q36; p13) acute myeloid leukemia model shows high expression of MNX1 and a block in differentiation of the erythroid and
    T Nilsson, A Waraky, A stlund, S Li, A Staffas, J Asp, L Fogelstrand, ...
    International Journal of Cancer 151 (5), 770-782 2022

  • Mnx1 induces leukemia transformation through altering histone methylation in a model of pediatric t (7; 12) acute myeloid leukemia
    A Waraky, A stlund, T Nilsson, D Weichenhan, P Lutsik, M Bhr, J Hey, ...
    BiorXiv, 2022.06. 10.495634 2022

  • MNX1 INDUCES LEUKEMIA TRANSFORMATION THROUGH INTERACTION WITH THE METHIONINE CYCLE IN A MODEL OF PEDIATRIC T (7; 12) ACUTE MYELOID LEUKEMIA
    A Waraky, A Ostlund, C NIlsson, M Hamdy, L Fogelstrand, L Palmqvist
    EXPERIMENTAL HEMATOLOGY 100, S110-S110 2021

  • 3140–MNX1 INDUCES LEUKEMIA TRANSFORMATION THROUGH INTERACTION WITH THE METHIONINE CYCLE IN A MODEL OF PEDIATRIC T (7; 12) ACUTE MYELOID LEUKEMIA
    A Waraky, A Ostlund, C NIlsson, M Hamdy, L Palmqvist
    Experimental Hematology 100, S109-S110 2021

  • 3144–ECTOPIC EXPRESSION OF THE HOMEOBOX GENE MNX1 IS THE TRANSFORMING EVENT IN A MOUSE MODEL OF PEDIATRIC T (7; 12)(Q36; P13) PEDIATRIC ACUTE MYELOID LEUKEMIA
    A Waraky, A stlund, T Nilsson, J Adamsson, M Hamdy, L Arabanian, ...
    Experimental Hematology 88, S82-S83 2020

  • Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers
    C Yang, Y Zhang, Y Chen, F Ragaller, M Liu, S Corvigno, H Dahlstrand, ...
    PLoS One 15 (7), e0236291 2020

  • The Translocation t (7; 12)(q36; p13) Induces Myeloid Leukemia in Immuno-Compromised but Not Immunocompetent Mice
    A Waraky, A stlund, L Arabanian, T Nilsson, L Fogelstrand, L Palmqvist
    Blood 134, 2707 2019

  • Recreation of t (7; 12)(q36; p13) in Human Induced Pluripotent Stem Cells Using CRISPR/Cas9 Generates a Useful Model for Studying Acute Myeloid Leukemia
    T Nilsson, A Waraky, A stlund, L Arabanian, J Asp, L Fogelstrand, ...
    Blood 134, 2736 2019

  • Degradation of pristine and oxidized single wall carbon nanotubes by CYP3A4
    R El-Sayed, A Waraky, K Ezzat, R Albabtain, K Elgammal, S Shityakov, ...
    Biochemical and biophysical research communications 515 (3), 487-492 2019

  • Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage
    A Waraky, Y Lin, D Warsito, F Haglund, E Aleem, O Larsson
    Journal of Biological Chemistry 292 (44), 18227-18239 2017

  • SUMO‐modified insulin‐like growth factor 1 receptor (IGF‐1R) increases cell cycle progression and cell proliferation
    Y Lin, H Liu, A Waraky, F Haglund, P Agarwal, H Jernberg‐Wiklund, ...
    Journal of cellular physiology 232 (10), 2722-2730 2017

  • Insulin-Like Growth Factor 1 Receptor, Novel Functions and Future Possibilities
    A Waraky
    PQDT-Global 2017

  • Abstract B16: The nuclear IGF-1R regulates DNA damage tolerance through tyrosine phosphorylation of PCNA in human embryonic stem cells
    A Waraky, Y Lin, E Aleem, O Larsson
    Molecular Cancer Research 14 (11_Supplement), B16-B16 2016

  • Downregulation of IGF-1 receptor occurs after hepatic linage commitment during hepatocyte differentiation from human embryonic stem cells
    A Waraky, E Aleem, O Larsson
    Biochemical and biophysical research communications 478 (4), 1575-1581 2016

  • Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism
    A Waraky, K Akopyan, V Parrow, T Strmberg, M Axelson, L Abrahmsn, ...
    Oncotarget 5 (18), 8379 2014

  • THE ANTI-TUMOR EFFECTS OF PICROPODOPHYLLIN ON HEPATOCARCINOMA HEPG2 CELL LINE
    E Aleem, EE Hafez, O Larsson


MOST CITED SCHOLAR PUBLICATIONS

  • SUMO‐modified insulin‐like growth factor 1 receptor (IGF‐1R) increases cell cycle progression and cell proliferation
    Y Lin, H Liu, A Waraky, F Haglund, P Agarwal, H Jernberg‐Wiklund, ...
    Journal of cellular physiology 232 (10), 2722-2730 2017
    Citations: 44

  • Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage
    A Waraky, Y Lin, D Warsito, F Haglund, E Aleem, O Larsson
    Journal of Biological Chemistry 292 (44), 18227-18239 2017
    Citations: 37

  • Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism
    A Waraky, K Akopyan, V Parrow, T Strmberg, M Axelson, L Abrahmsn, ...
    Oncotarget 5 (18), 8379 2014
    Citations: 29

  • Downregulation of IGF-1 receptor occurs after hepatic linage commitment during hepatocyte differentiation from human embryonic stem cells
    A Waraky, E Aleem, O Larsson
    Biochemical and biophysical research communications 478 (4), 1575-1581 2016
    Citations: 19

  • Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers
    C Yang, Y Zhang, Y Chen, F Ragaller, M Liu, S Corvigno, H Dahlstrand, ...
    PLoS One 15 (7), e0236291 2020
    Citations: 12

  • An induced pluripotent stem cell t (7; 12)(q36; p13) acute myeloid leukemia model shows high expression of MNX1 and a block in differentiation of the erythroid and
    T Nilsson, A Waraky, A stlund, S Li, A Staffas, J Asp, L Fogelstrand, ...
    International Journal of Cancer 151 (5), 770-782 2022
    Citations: 9

  • Degradation of pristine and oxidized single wall carbon nanotubes by CYP3A4
    R El-Sayed, A Waraky, K Ezzat, R Albabtain, K Elgammal, S Shityakov, ...
    Biochemical and biophysical research communications 515 (3), 487-492 2019
    Citations: 6

  • Aberrant MNX1 expression associated with t (7; 12)(q36; p13) pediatric acute myeloid leukemia induces the disease through altering histone methylation
    A Waraky, A stlund, T Nilsson, D Weichenhan, P Lutsik, M Bhr, J Hey, ...
    Haematologica 109 (3), 725 2024
    Citations: 2

  • Mnx1 induces leukemia transformation through altering histone methylation in a model of pediatric t (7; 12) acute myeloid leukemia
    A Waraky, A stlund, T Nilsson, D Weichenhan, P Lutsik, M Bhr, J Hey, ...
    BiorXiv, 2022.06. 10.495634 2022
    Citations: 2

  • The Translocation t (7; 12)(q36; p13) Induces Myeloid Leukemia in Immuno-Compromised but Not Immunocompetent Mice
    A Waraky, A stlund, L Arabanian, T Nilsson, L Fogelstrand, L Palmqvist
    Blood 134, 2707 2019
    Citations: 2