A Mobile Application to Guide Healthcare Professionals in the Correct Technique for Personal Protective Equipment Use during the COVID-19 Pandemic Geraldo Magela Salomé, Adriana Rodrigues dos Anjos Mendonça, Marcus Vinicius Teixeira de Almeida, Flávio Dutra Miranda Journal of Coloproctology, 2021 Objectives The present study aimed to develop an application to guide healthcare professionals on using personal protective equipment (PPE) during the COVID-19 pandemic and prevent and treat skin lesions caused by these devices.Methods This is a study on technological production. The framework for application development consisted in the following phases: Phase 1–“Design: identification of application development requirements;” Phase 2–“Application prototype development”: including an integrative literature review in major databases; Phase 3–“Application construction”: elaboration of the decision tree, algorithm, database structuring, and software development; Phase 4–“Transition”: application functionality test.Result Our application Simplifica EPI is an innovative technology; this software is a tool to assist healthcare professionals in using PPE. In addition, it describes how to prevent and care for skin lesions caused by PPE. Simplifica EPI has 25 screens and 32 images. It will be available on the Google Play Store after its registration with the Brazilian National Institute of Industrial Property.Conclusions After an integrative literature review, the application Simplifica EPI was developed as an innovative technology with great potential for use by healthcare professionals.
Elaboration and Validation of Flowchart for the Prevention and Treatment of Intestinal Peristomal Skin Complications Imaculada Aparecida Cardoso, Geraldo Magela Salomé, Adriana Rodrigues Dos Anjos Mendonça, Flávio Dutra Miranda, José Ronaldo Alves Journal of Coloproctology, 2021 Objective To build and validate a flowchart for the prevention and treatment of intestinal peristomal skin complications. Method For the construction of the algorithms, a systematic review was carried out in health sciences databases comprising the last 10 years. The evaluation of the algorithms was carried out by 38 nurses. For the validation of the algorithms, the Delphi technique was used. The statistical analysis used was the content validity index and the Cronbach alpha coefficient. The questionnaire was sent by e-mail and in person after approval by the Ethics and Research Committee. Results In the first evaluation of the algorithms, there was no agreement among the experts. However, after making the corrections suggested by the evaluators, the algorithms were resent, with a 100% consensus among the evaluators. The questions used to validate the algorithms contributed favourably to the internal consistency and content validation of the instrument, since the respective Cronbach alpha was 0.9062 and the global content validity index (g-CVI) was 0.91 in the first validation and 1.0 in the second validation. Conclusion After an integrative literature review, the flowcharts were built and validated by a professional with experience in the area, showing 100% agreement among the experts in the second evaluation.
Peristomal Dermatitis: Treatment with Green Banana Peel (Musa sapientum) Powder Ana Cristina da Silva, Isabella Stephanie Simões, Geraldo Magela Salomé, Dênia Amélia Novato Castelli von Atzingen, Adriana Rodrigues dos Anjos Mendonça Journal of Coloproctology, 2021 Objective To develop green banana peel (Musa sapientum) powder for the treatment of peristomal dermatitis, and to evaluate its effectiveness and healing time. Methods A clinical, analytical and longitudinal study. In total, 44 volunteers of both genders, aged > 18 years, with intestinal ostomy, who presented peristomal dermatitis, participated in the research. The sample was divided into two groups: the study group used a powder containing 10% of green banana peel, and the control group used ostomy powder. The research was approved by the Ethics in Research Committees (Comitês de Ética em Pesquisa, CEP, in Portuguese) under opinion n° 2.381.904. Results The healing time of the study group was shorter than that of the control group (p = 0.022). To analyze the results, we used the two-sample t-test (mean days until healing for both study groups). Conclusion The powder containing 10% of green banana peel was developed, and effective healing of the peristomal dermatitis was observed. Compared to the ostomy powder, it presented a shorter healing time.
A new APP for prevention and treatment of complications of intestinal peristomal skin Imaculada Aparecida Cardoso, Geraldo Magela Salomé, Flávio Dutra Miranda, José Ronaldo Alves, João Paulo Pereira Leão, Alex Sandro Leão, Adriana Rodrigues dos Anjos Mendonça Journal of Coloproctology, 2021 Objectives To develop an application program for prevention and treatment of complications of intestinal peristomal skin. Method The framework of the application software development were: Phase 1 – “Design, identification of the needs for the application development”: In this phase, the authors identified during their clinical practice that some professionals and caregivers find it difficult to provide care for at-risk ostomized patients or those with some kind of peristomal skin complication; Phase 2 – “Application prototype development”: this phase included the integrative literature review in the main databases; Phase 3 – “Creating the application”: this phase was intended to generate a decision tree algorithms, structure the database, and develop the software; Phase 4 – “Transition”: performing the application functionality testing. Results The application “Dermatite Periestoma App” has 36 screens and 21 figures describing the procedures for prevention and treatment of complications of intestinal peristomal skin. It is freely available from the Play Store and has been registered with the Instituto Nacional da Propriedade Industrial Ministério do Desenvolvimento, indústria e Comércio Exterior (Brazilian Ministry of Development, Industry and Foreign Trade, National Institute of Industrial Property). Conclusion This study made it possible to describe the stages of planning and development of the mobile application “Dermatite Periestoma App”. The steps taken indicate that the “Dermatite Periestoma App” has great potential for clinical practice in the evaluation of patients with stomal complications or at risk for developing peristomal skin complications, preventive measures, therapeutic approaches, and for nursing education through the use of technology.
KAP-COVID GLOBAL: A multinational survey of the levels and determinants of public knowledge, attitudes and practices towards COVID-19 Ahmed Taher Masoud, Mohamed Sayed Zaazouee, Sarah Makram Elsayed, Khaled Mohamed Ragab, Esraa M Kamal, Yusra T Alnasser, Ahmed Assar, Anas Z Nourelden, Loai J Istatiah, Mohamed M Abd-Elgawad, Ahmed T Abdelsattar, Ahmed A Sofy, Doaa G Hegazy, Victor Z Femía, Adriana R Mendonça, Fatma M Sayed, Ahmed Elmoursi, Alaa Alareidi, Ahmed K Abd-Eltawab, Mohamed Abdelmonem, Omar M Mohammed, EzzEldeen A Derballa, Kareem A El-Fas, Mohamed M. Abdel-Daim, Abdelrahman I. Abushouk BMJ Open, 2021 ObjectiveThe adherence to public health recommendations to control COVID-19 spread is influenced by public knowledge, attitudes and practices (KAP). We performed this cross-sectional study to assess the levels and determinants of public KAP towards COVID-19 in a large, multinational sample.DesignCross-sectional study (survey).SettingThe questionnaire was distributed to potential respondents via online platforms.Participants71 890 individuals from 22 countries.MethodsWe formulated a four-section questionnaire in English, followed by validation and translation into seven languages. The questionnaire was distributed (May to June 2020) and each participant received a score for each KAP section.ResultsOverall, the participants had fair knowledge (mean score: 19.24±3.59) and attitudes (3.72±2.31) and good practices (12.12±1.83) regarding COVID-19. About 92% reported moderate to high compliance with national lockdown. However, significant gaps were observed: only 68.2% knew that infected individuals may be asymptomatic; 45.4% believed that antibiotics are an effective treatment; and 55.4% stated that a vaccine has been developed (at the time of data collection). 71.9% believed or were uncertain that COVID-19 is a global conspiracy; 36.8% and 51% were afraid of contacting doctors and Chinese people, respectively. Further, 66.4% reported the pandemic had moderate to high negative effects on their mental health. Female gender, higher education and urban residents had significantly (p≤0.001) higher knowledge and practice scores. Further, we observed significant correlations between all KAP scores.ConclusionsAlthough the public have fair/good knowledge and practices regarding COVID-19, significant gaps should be addressed. Future awareness efforts should target less advantaged groups and future studies should develop new strategies to tackle COVID-19 negative mental health effects.
End of life: Bioethical reflection on medical education Izaura Mariana Sobreiro, Priscelly Cristina Castro Brito, Adriana Rodrigues dos Anjos Mendonça Revista Bioetica, 2021 Resumo Nesta pesquisa qualitativa, utilizou-se o método do discurso do sujeito coletivo para conhecer os significados, sentimentos e percepções de estudantes de medicina sobre o tema morte e pacientes terminais. Foram entrevistados 60 alunos de uma universidade do Sul de Minas Gerais. Para os significados sobre terminalidade da vida, a ideia central mais frequente foi “fechamento da vida”. Quando o tema abordado foi o sentimento a respeito do paciente terminal, emergiram as ideias centrais “insegurança”, “impotência”, “frustração” e “angústia”. Quanto ao preparo para lidar com a morte e o morrer, prevaleceu a ideia “não estou preparado”. Já com relação à presença desses temas na formação, surgiram as ideias “abordagem superficial”, “deveriam ser abordados com mais frequência” e “não abordados”. Conclui-se que a formação médica não trata da inexorabilidade da morte, o que afasta a possibilidade de repensar o cuidado como forma terapêutica.
Algorithms for the prevention and treatment of friction injury Renan Vinicius Pinheiro, Geraldo Magela Salomé, Flávio Dutra Miranda, José Ronaldo Alves, Fernanda Aparecida dos Reis, Adriana Rodrigues dos Anjos Mendonça Acta Paulista De Enfermagem, 2021 Resumo Objetivo: Elaborar e validar o conteudo de algoritmos para prevencao e tratamento de lesao por friccao. Metodos: Para a construcao dos algoritmos, foi realizada uma revisao integrativa da literatura apos busca nas bases de dados: SciELO, LILACS e MEDLINE. A avaliacao dos algoritmos foi realizada por 26 juizes, sendo 10 medicos e 16 enfermeiros, utilizando-se a tecnica Delphi. Os resultados foram analisados por meio do Indice de Validade de Conteudo. Resultados: No primeiro ciclo de avaliacao, os itens dos [...]
Applicability of eucalyptus wood waste extracts for the histological staining of connective tissue Rodrigo Machado Pereira, Danilo Gabriel Oliveira, Francisco Eduardo de Carvalho Costa, Fiorita Gonzales Lopes Mundim, Adriana Rodrigues dos Anjos Mendonça Journal of Histotechnology, 2020 Biological staining of tissue is a crucial procedure in histotechnology. Rudimentary methods for section preparation have often used stains from natural products, although use of synthetic dyes has become the contemporary standard. Artificial dyes increase the operating costs of a laboratory as well as increase the environmental and personnel risks during manufacturing and usage. These considerations have stimulated research to find alternative natural stains from the wide diversity of plant species. The present study investigated the effect of Eucalyptus sp. (Myrtaceae) wood waste extract on histological staining of animal tissues, using a series of pigment concentrations, pH conditions, and temperatures. Eucalyptus wooden slivers were dried, milled, and 1 g, 2 g, and 4 g of the fine powder was subjected to 50% ethanol extraction for 2 days. Staining tests were then performed on formalin fixed paraffin embedded (FFPE) sections. Increasing acetic acid concentrations (1%, 2% and 4%) were added to the extracts and compared to an acid-free extract. Staining was performed at both ambient room temperature (RT) and 60°C. Connective tissue acidophilic components were well-contrasted and a hematoxylin counterstain demonstrated distinct structural differences between matrix and cell nuclei. Therefore, the present findings demonstrate the potential utility of the eucalyptus wood extracts application as a natural stain alternative for routine histology.
Vaccination in brazil: Bioethical reflection on accessibility Elisa Coutinho Moura, Camila Rezende dos Santos, Dênia Amélia Novato Castelli von Atzingen, Adriana Rodrigues dos Anjos Mendonça Revista Bioetica, 2020 Resumo As vacinas têm grande influência na saúde pública por sua efetividade e relação custo-benefício favorável. Entretanto, com o surgimento de novos imunizantes indisponíveis na rede pública, torna-se necessário discutir o acesso da sociedade em geral. O objetivo deste trabalho foi identificar o significado da vacinação para profissionais e população, assim como abordar a questão do acesso à imunização fora da rede pública de saúde, enfatizando a vulnerabilidade social. Foram entrevistados médicos e cidadãos leigos, e os dados foram analisados a partir de metodologia qualitativa exploratória e do discurso do sujeito coletivo. O sistema vacinal brasileiro foi entendido pelos entrevistados como bom de maneira geral, sendo as principais críticas voltadas à falta de informações e insumos. Quanto ao acesso, os dados sugerem correlação com fatores econômicos, abrindo espaço para discussões bioéticas sobre a vulnerabilidade social da maior parte da população, que não tem condições de pagar por essas imunizações.
In vitro and in vivo antimicrobial activity of cymbopogon citratus (DC.) Stapf. Against staphylococcus spp. isolated from newborn babies in an intensive care unit João Batista Oliveira, Manoel Araújo Teixeira, Luiz Francisley de Paiva, Rafaela Faria de Oliveira, Adriana Rodrigues dos Anjos Mendonça, Maria José Azevedo de Brito Microbial Drug Resistance, 2019 Phytotherapy is an emerging topic of health research, with particular focus on studying the efficiency of essential oils as antimicrobials. In this study, we investigated the in vitro and in vivo susceptibility of Staphylococcus strains isolated from newborns to Cymbopogon citratus oil. The in vitro susceptibility of the microorganisms to C. citratus essential oil was compared with the activities of standard antibiotics administered to newborns using disk diffusion and microdilution methods. For in vivo assessment, 30 Wistar rats were wounded and subjected to infection of Staphylococcus aureus strain DRJ080, followed by treatment with the antibiotic vancomycin, C. citratus, or carbopol polymer gel (control) for 11 days. S. aureus accounted for 23.36% of the 107 Staphylococcus sp. strains isolated. Both vancomycin and the essential oil of C. citratus inhibited the growth of all microorganisms in vitro. The minimum inhibitory and bactericidal concentrations for the C. citratus oil were 0.625 mg/mL in all strains tested. The oil had the same therapeutic effectiveness as vancomycin against S. aureus DRJ080 in rats. Thus, Staphylococcus strains of newborns are sensitive to C. citratus oil, both in vitro and in vivo, demonstrating its potential as an antibiotic alternative.
Unripe musa sapientum peel in the healing of surgical wounds in rats Dênia Amélia Novato Castelli Von Atzingen, Alfredo Gragnani, Daniela Francescato Veiga, Luis Eduardo Felipe Abla, Lorraine Lorene Felix Cardoso, Thiago Ricardo, Adriana Rodrigues dos Anjos Mendonça, Lydia Masako Ferreira Acta Cirurgica Brasileira, 2013
Gel from unripe Musa sapientum peel to repair surgical wounds in rats Dênia Amélia Novato Castelli Von Atzingen, Alfredo Gragnani, Daniela Francescato Veiga, Luis Eduardo Felipe Abla, Adriana Rodrigues dos Anjos Mendonça, Clayton Aparecido de Paula, Yara Juliano, José Carlos Correa, Marcio Raimundo de Faria, Lydia Masako Ferreira Acta Cirurgica Brasileira, 2011
Leukemia and extracelular matrix Revista Brasileira De Hematologia E Hemoterapia, 2000
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