@rcpcollege.edu.in
Pharmacology
Roorkee College of Pharmacy
Introduction
Assistant Professor and Pharmacologist, Currently serving in Education Department (U.K.) India. Editorial Board Member in EMC, Singapore.
Disciplines
Clinical PharmacologyPharmacologyPharmacyGastroenterologyDevelopmental BiologyImmunology
Skills and expertise
GastroenterologyChinese Herbal MedicineMedicinal ChemistryMedicinal Plants and HerbsNatural Product PharmacologyNew Drug DevelopmentNew Drug DiscoveryAyurvedic Medicineayurvedic herb
Languages
EnglishHindi
• Completed M. Pharm. (Pharmacology) from Rajiv Academy for Pharmacy, Mathura (U.P.) India, (2021-2023).
• Completed B. Pharm. from Rajiv Academy for Pharmacy, Mathura (U.P.) India, (2017-2021).
• Completed Intermediate (10+2) from SRI G S I C BHUTIYA PANIGAON, Mathura (U.P.) India (2017).
• Completed High School (10th) from KENDRIYA VIDYALAY- 2, Mathura (U.P.) India (2015).
Pharmacology, Toxicology and Pharmaceutics, General Pharmacology, Toxicology and Pharmaceutics, Drug Discovery, Pharmacology
Scopus Publications
Shireen Ansari, Sushmita Uniyal, Ayushi Khali, Rishabh Gaur, and Karabi Kalita
Elsevier BV
Sonal Bansal, Km Pratiksha, Rishabh Gaur, Somya Gupta, Ved Prakash Jadaun, and Vibha Kumari
Elsevier BV
Rishabh Gaur
Elsevier BV
Aarti Rajput, Rishabh Gaur, Mayank Kulshreshtha, Sumedha Singh Jadaun, and Vibha Kumari
Bentham Science Publishers Ltd.
Background: Emulgel combines the qualities of an emulsion with those of a gel. In order to create an emulgel w/o or o/w, emulsions have to be formulated, which are then com-bined with a gelling agent, resulting in a dual-control drug release. Celecoxib exhibits analge-sic, antipyretic and anti-inflammatory activities and is used to treat osteoarthritis, severe pain, rheumatoid arthritis, and other medical conditions. Methods: Celecoxib Emulgel was developed and evaluated by using natural oil and carbopol-940 as a gelling agent in different concentrations. The screening of various oils, co-surfactants and surfactants was performed to determine the solubility. The essential oils (eucalyptus oil and turpentine oil) were used as penetration modifiers. Studies on compatibility with polymers have been conducted, and the results indicate that there should be no physical or chemical interactions between the polymers and the drug substance. For the preparation of emulgel, various emulsions were prepared with Smix (cosurfactant and surfactant) ratios (1:1, 2:1 and 3:1). The selection of a gelling agent was done by incorporating the selected emulsion system ratio of 1:1 with the combinations of polymers carbapol 940, carbapol 934, and HPMC (0:1:0, 0:0.5:1, 0:0:3, 0.5:0:1, 1:0:0) gel base to make a homogenous emulgel. Results: The emulgel was examined visually to see if it had any phase behaviour, feel, spread-ability, and grittiness by applying its thin layer to a slide. Then, all six formulations of emulgel were prepared with the selected gelling agent. All emulgels were evaluated for pH, physical properties (consistency, homogeneity, colour, texture), drug content, spreadability, extrudabil-ity, swelling index, viscosity, stability and centrifugation. A Franz diffusion cell and an egg membrane were used to perform in-vitro drug release. Conclusion: Among all prepared formulations, EG1 had a better release, higher viscosity, higher drug content, and a higher swelling index than the others. The formulation EG1 showed higher drug release (91.25%) within 8 hours.
1. Rishabh Gaur, Anuj Kumar Sharma, Devender Pathak, Mayank Kulshreshtha, “Scientific update on the Pharmacognostic, Pharmacological and Phytochemical properties of Thevetia peruviana: Phytopharmacological update on Thevetia peruviana” . (Published in 2023).
2. Rishabh Gaur " A Brief History: Traditional Chinese Medicinal System" Pharmacological Research - Modern Chinese Medicine, Elsevier. (Published, Scopus Indexed).
3. Rishabh Gaur, Mayank Kulshreshtha, “A comprehensive Review on Peptic Ulcer” Current Nutraceuticals, Bentham Science (Published in 2023).
4. Mohit Sandhuja, Rishabh Gaur, Anuj Kumar Sharma, Mayank Kulshreshtha “Regulatory Pathways for Ayurvedic Formulations in India”. Current Nutraceuticals, Bentham Science (Published in 2023).
5. Prashant Kumar, Rishabh Gaur, Devender Pathak, Mayank Kulshreshtha “An overview of anti-diabetic Efficacy and Biochemical Mechanism of Anisomeles malabarica (Malabar catmint): A Review” Bioequivalence & Bioavailability Journal (MedWin Publishers, Published in 2023).
6. Aarti Rajput, Rishabh Gaur, Km. Vibha. “Development and Evaluation of Emulgel of Celecoxib by using Natural Oil”. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (Bentham Science, Scopus Indexed, Published in 2024).
7. Kehar Singh, Mohit Sandhuja, Rishabh Gaur, Sunil Thakral, Mayank Kulshreshtha. “Phytopharmacological Updates on Mentha longifolia: A Comprehensive Review”. Free Radicals and Antioxidants (Published in 2024).