MUSTAFA SAFA PEPELE

@ozal.edu.tr

medical doctor medicine faculty
malatya turgut özal üniversitesi tıp fakültesi

RESEARCH, TEACHING, or OTHER INTERESTS

Emergency Medicine, Toxicology, Critical Care and Intensive Care Medicine

4

Scopus Publications

Scopus Publications

  • Evaluation of patients directed from emergency department to dermatology clinic
    Zekiye KANAT and Mustafa Safa PEPELE

    Turkiye Klinikleri

  • The diagnostic role of adiponectin in pulmonary embolism
    Evrim Gul, Yeliz Gul, Ersin Yıldırım, Mustafa Safa Pepele, Mustafa Yıldız, Mehmet Nuri Bozdemir, Mehmet Ruhi Onur, Bengü Mutlu, Feti Yıldız, Ömer Doğan Alataş,et al.

    Hindawi Limited
    Background and Aims. Pulmonary thromboembolism (PTE) is a frequent disease with difficult diagnosis and high mortality. Misdiagnosis occurs in 2/3 patients and mortality rates reach up to 30%. The aim of our study was to investigate the role of adiponectin used in emergency service in diagnosis of PTE.Materials and Methods. 95 patients with suspected PTE included in the study. Plasma adiponectin and D-dimer levels were measured and chest X-ray and multidetector row computed tomography scan obtained. Diagnosis was supported by vascular filling defect on tomography. Control group consisted of patients with suspected PTE and normal chest computed tomography findings.Results. Mean D-dimer level was4241.66±1082.98 ng/mL in patients and2211.21±1765.53 ng/mL in the control group (p≤0.05). Mean adiponectin level was5.46±4.39 μg/mL in patients and7.68±4.67 μg/mL in the control group (p≤0.05). Wells and Geneva scores were higher in patients compared to the control group.Conclusions. As a result, we conclude that lower adiponectin levels have an important role in the diagnosis of PTE.

  • Moxifloxacin hydrochloride related visual hallucinations: A case presentation
    Mustafa Safa Pepele, Cem Ertan, and Neslihan Yucel

    Medknow
    Giriş Acil servise nörolojik semptomlarla başvuran bir hastada organik beyin hastalıkları ve psikiyatrik nedenler öncelikli ayırıcı tanılar olsa da, diğer metabolik nedenler ve ilaç yan etkileri gibi olası etkenler de göz önünde bulundurulmalıdır. Moksifloksasin florokinolon grubundan geniş etki spektrumuna sahip yeni nesil bir antibiyotiktir. Başlıca endikasyonları komplike idrar yolu enfeksiyonları ve alt solunum yolu enfeksiyonları olarak sayılabilir. Halsizlik, baş dönmesi, çarpıntı, döküntüler gibi görece olarak sık görülebilen yan etkilerinin SUMMARY Although the foremost encountered differential diagnosis in patients with neurological complaints in the emergency departments (ED) are organic nervous system diseases and psychiatric disorders, other metabolic disturbances and drug related adverse effects shall be considered as well. We present a 65 year old female patient who attended to our ED with visual hallucinations such as orange colored wallpaper, boiling water on the ground and wave patterns for the last 3 hours. Past medical history was clear for all but chronic obstructive pulmonary disease. Neuropsychiatric examination revealed a fully oriented, neurologically intact patient. After further questioning, we learned that the patient was on moxifloxacin 400 mg PO for two days and the symptoms started following the first dose of moxifloxacin. Laboratory and radiological work up including brain CT showed no pathognomonic findings. The patient, whose complaints totally resolved at the 6th hour of her follow-up in the ED was discharged with the diagnosis of “Moxifloxacin related visual hallucinations” with relevant modifications on her antibacterial treatment. Telephone follow-up 24 hours later revealed that our patient was symptom free.

  • Paediatric trauma patients and attention deficit hyperactivity disorder: Correlation and significance
    Cem Ertan, Özlem Özel Özcan, and Mustafa Safa Pepele

    BMJ
    Introduction Trauma is one of the leading reasons for emergency department (ED) visits in children. Hyperactivity, inattentiveness and impulsiveness may contribute to injury proneness. The aim of this study was to evaluate the prevalence and role of attention deficit hyperactivity disorder (ADHD) in children with trauma. Methods Trauma patients aged 3–17 attending the ED were included in the study group. Parents were informed after medical care had been given to their children, and demographic data and information about the trauma were collected. Later, parents were asked to complete the Conners' Parent Rating Scales-Revised questionnaire for ADHD symptoms. The control group consisted of children of similar age and sociocultural characteristics who attended the hospital for reasons other than trauma. Cases in which the child apparently had no active role in the trauma or where the parents did not complete the Conners' Parent Rating Scales-Revised questionnaire were excluded from the study. Results Fifty-five children were included in the study group (mean age 7.49 (range 3–14; SD 3.3); 33 (60%) were male). The control group was statistically similar to the study group. The most common trauma mechanism was falls (n=31, 56.4%). All the subscale scores were significantly higher in the study group, and previous trauma-related ED visits were associated with significantly higher subscale scores. Conclusion The data suggest that children who make repeated trauma-related ED visits have a predisposition to ADHD, and they may benefit from screening for this disorder while in the ED.