KEWAL KUMAR MAHAPATRA

@cgu-odisha.ac.in

Assistant Professor in Zoology
C. V. Raman Global University, Bhubaneswar, Odisha

KEWAL KUMAR MAHAPATRA


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https://researchid.co/kewal001

RESEARCH, TEACHING, or OTHER INTERESTS

Animal Science and Zoology, Cancer Research, Cell Biology, Molecular Biology
36

Scopus Publications

1974

Scholar Citations

19

Scholar h-index

25

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • Chebulagic acid limits mTOR activity leading to TFEB-driven autophagy and lysosomal biogenesis to suppress the arecoline-induced NLRP3-mediated inflammasome axis in OSCC
    PK Senapati, A Singh, RK Kar, KK Mahapatra, S Maiti, M Jena, SK Bhutia
    Available at SSRN 6189047 , 2026
    2026
  • PPA2 activates MTFP1-DNM1L fission signaling to govern mitochondrial proliferation and mitophagy
    SR Mishra, P Mishra, KK Mahapatra, BP Behera, G Kendre, MR Alotaibi, ...
    Autophagy 22 (1), 121-144 , 2026
    2026
    Citations: 5
  • Intricate role of DRP1 and associated mitochondrial fission signaling in carcinogenesis and cancer progression
    SR Mishra, P Mishra, PK Senapati, KK Mahapatra, SK Bhutia
    Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 189453 , 2025
    2025
    Citations: 4
  • Autophagy paradox: Genetic and epigenetic control of autophagy in cancer progression
    CS Bhol, PK Senapati, RK Kar, G Chew, KK Mahapatra, EHC Lee, ...
    Cancer letters, 217909 , 2025
    2025
    Citations: 14
  • mTOR inhibitors in targeting autophagy and autophagy-associated signaling for cancer cell death and therapy
    PK Senapati, KK Mahapatra, A Singh, SK Bhutia
    Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1880 (3), 189342 , 2025
    2025
    Citations: 29
  • Molecular regulation of mitophagy signaling in tumor microenvironment and its targeting for cancer therapy
    BP Behera, SR Mishra, S Patra, KK Mahapatra, CS Bhol, DP Panigrahi, ...
    Cytokine & growth factor reviews , 2025
    2025
    Citations: 18
  • Prolonged glutamine starvation reactivates mTOR to inhibit autophagy and initiate autophagic lysosome reformation to maintain cell viability
    A Singh, KK Mahapatra, PP Praharaj, S Patra, SR Mishra, S Patil, ...
    The International Journal of Biochemistry & Cell Biology 177, 106694 , 2024
    2024
    Citations: 8
  • Original SIRT1-activating butein inhibits arecoline-induced mitochondrial dysfunction through PGC1 alpha and MTP18 in oral cancer
    BP Behera, SR Mishra, KK Mahapatra, S Patil, T Efferth, SK Bhutia
    Phytomedicine 129 , 2024
    2024
    Citations: 1
  • SIRT1-activating butein inhibits arecoline-induced mitochondrial dysfunction through PGC1α and MTP18 in oral cancer
    BP Behera, SR Mishra, KK Mahapatra, S Patil, T Efferth, SK Bhutia
    Phytomedicine 129, 155511 , 2024
    2024
    Citations: 13
  • Recent advancement of autophagy in polyploid giant cancer cells and its interconnection with senescence and stemness for therapeutic opportunities
    S Patra, PP Naik, KK Mahapatra, MR Alotaibi, S Patil, BS Patro, G Sethi, ...
    Cancer Letters 590, 216843 , 2024
    2024
    Citations: 16
  • Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma
    SR Mishra, BP Behera, VK Singh, KK Mahapatra, D Mundkinajeddu, ...
    Phytomedicine 123, 155157 , 2024
    2024
    Citations: 13
  • Autophagic lysosome reformation: The beginning from the end
    KK Mahapatra, SK Bhutia
    Autophagy Processes and Mechanisms, 153 , 2023
    2023
  • Stonin 2 activates lysosomal-mTOR axis for cell survival in oral cancer
    KK Mahapatra, SR Mishra, R Dhiman, SK Bhutia
    Toxicology in Vitro 88, 105561 , 2023
    2023
    Citations: 5
  • Deciphering The Role Of Stonin 2 In Autophagy and Autophagic Lysosome Reformation to Control Cell Survival in Oral Squamous Cell Carcinoma
    KK Mahapatra
    2023
  • Autophagy for secretory protein: Therapeutic targets in cancer
    KK Mahapatra, S Patra, SR Mishra, BP Behera, S Patil, SK Bhutia
    Advances in Protein Chemistry and Structural Biology 133, 159-180 , 2023
    2023
    Citations: 8
  • Recent progress of autophagy signaling in tumor microenvironment and its targeting for possible cancer therapeutics
    S Mukhopadhyay, KK Mahapatra, PP Praharaj, S Patil, SK Bhutia
    Seminars in cancer biology 85, 196-208 , 2022
    2022
    Citations: 76
  • Inflammasomes in cancer: Effect of epigenetic and autophagic modulations
    SR Mishra, KK Mahapatra, BP Behera, CS Bhol, PP Praharaj, ...
    Seminars in Cancer Biology 83, 399-412 , 2022
    2022
    Citations: 28
  • Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives
    S Patra, SR Mishra, BP Behera, KK Mahapatra, DP Panigrahi, CS Bhol, ...
    Seminars in cancer biology 80, 205-217 , 2022
    2022
    Citations: 141
  • The lysosome as an imperative regulator of autophagy and cell death
    KK Mahapatra, SR Mishra, BP Behera, S Patil, DA Gewirtz, SK Bhutia
    Cellular and Molecular Life Sciences 78 (23), 7435-7449 , 2021
    2021
    Citations: 227
  • Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics
    SR Mishra, KK Mahapatra, BP Behera, S Patra, CS Bhol, DP Panigrahi, ...
    The international journal of biochemistry & cell biology 136, 106013 , 2021
    2021
    Citations: 192

MOST CITED SCHOLAR PUBLICATIONS

  • The emerging, multifaceted role of mitophagy in cancer and cancer therapeutics
    DP Panigrahi, PP Praharaj, CS Bhol, KK Mahapatra, S Patra, BP Behera, ...
    Seminars in cancer biology 66, 45-58 , 2020
    2020
    Citations: 348
  • The lysosome as an imperative regulator of autophagy and cell death
    KK Mahapatra, SR Mishra, BP Behera, S Patil, DA Gewirtz, SK Bhutia
    Cellular and Molecular Life Sciences 78 (23), 7435-7449 , 2021
    2021
    Citations: 227
  • Mitochondrial dysfunction as a driver of NLRP3 inflammasome activation and its modulation through mitophagy for potential therapeutics
    SR Mishra, KK Mahapatra, BP Behera, S Patra, CS Bhol, DP Panigrahi, ...
    The international journal of biochemistry & cell biology 136, 106013 , 2021
    2021
    Citations: 192
  • Plant lectins in cancer therapeutics: Targeting apoptosis and autophagy-dependent cell death
    SK Bhutia, PK Panda, N Sinha, PP Praharaj, CS Bhol, DP Panigrahi, ...
    Pharmacological research 144, 8-18 , 2019
    2019
    Citations: 165
  • Autophagy-modulating phytochemicals in cancer therapeutics: Current evidences and future perspectives
    S Patra, SR Mishra, BP Behera, KK Mahapatra, DP Panigrahi, CS Bhol, ...
    Seminars in cancer biology 80, 205-217 , 2022
    2022
    Citations: 141
  • Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics
    PP Praharaj, PP Naik, DP Panigrahi, CS Bhol, KK Mahapatra, S Patra, ...
    Cellular and Molecular Life Sciences 76 (9), 1641-1652 , 2019
    2019
    Citations: 111
  • Mitochondrial rewiring through mitophagy and mitochondrial biogenesis in cancer stem cells: A potential target for anti-CSC cancer therapy
    PP Praharaj, DP Panigrahi, CS Bhol, S Patra, SR Mishra, KK Mahapatra, ...
    Cancer letters 498, 217-228 , 2021
    2021
    Citations: 78
  • Recent progress of autophagy signaling in tumor microenvironment and its targeting for possible cancer therapeutics
    S Mukhopadhyay, KK Mahapatra, PP Praharaj, S Patil, SK Bhutia
    Seminars in cancer biology 85, 196-208 , 2022
    2022
    Citations: 76
  • Epigenetic modifications of autophagy in cancer and cancer therapeutics
    CS Bhol, DP Panigrahi, PP Praharaj, KK Mahapatra, S Patra, SR Mishra, ...
    Seminars in cancer biology 66, 22-33 , 2020
    2020
    Citations: 75
  • Terminalia bellirica extract induces anticancer activity through modulation of apoptosis and autophagy in oral squamous cell carcinoma
    S Patra, PK Panda, PP Naik, DP Panigrahi, PP Praharaj, CS Bhol, ...
    Food and Chemical Toxicology 136, 111073 , 2020
    2020
    Citations: 73
  • Dysregulation of histone deacetylases in carcinogenesis and tumor progression: a possible link to apoptosis and autophagy
    S Patra, DP Panigrahi, PP Praharaj, CS Bhol, KK Mahapatra, SR Mishra, ...
    Cellular and molecular life sciences: CMLS 76 (17), 3263 , 2019
    2019
    Citations: 63
  • Secretory clusterin promotes oral cancer cell survival via inhibiting apoptosis by activation of autophagy in AMPK/mTOR/ULK1 dependent pathway
    PP Naik, S Mukhopadhyay, PP Praharaj, CS Bhol, DP Panigrahi, ...
    Life Sciences 264, 118722 , 2021
    2021
    Citations: 52
  • Bioactive compounds from marine invertebrates as potent anticancer drugs: the possible pharmacophores modulating cell death pathways
    S Patra, PP Praharaj, DP Panigrahi, B Panda, CS Bhol, KK Mahapatra, ...
    Molecular biology reports 47 (9), 7209-7228 , 2020
    2020
    Citations: 45
  • Molecular interplay of autophagy and endocytosis in human health and diseases
    KK Mahapatra, DP Panigrahi, PP Praharaj, CS Bhol, S Patra, SR Mishra, ...
    Biological Reviews 94 (4), 1576-1590 , 2019
    2019
    Citations: 45
  • Monitoring and measuring mammalian autophagy
    SK Bhutia, PP Praharaj, CS Bhol, DP Panigrahi, KK Mahapatra, S Patra, ...
    Autophagy in Differentiation and Tissue Maintenance: Methods and Protocols … , 2018
    2018
    Citations: 39
  • Bacopa monnieri inhibits apoptosis and senescence through mitophagy in human astrocytes
    S Saha, KK Mahapatra, SR Mishra, S Mallick, VD Negi, I Sarangi, S Patil, ...
    Food and Chemical Toxicology 141, 111367 , 2020
    2020
    Citations: 31
  • mTOR inhibitors in targeting autophagy and autophagy-associated signaling for cancer cell death and therapy
    PK Senapati, KK Mahapatra, A Singh, SK Bhutia
    Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1880 (3), 189342 , 2025
    2025
    Citations: 29
  • Inflammasomes in cancer: Effect of epigenetic and autophagic modulations
    SR Mishra, KK Mahapatra, BP Behera, CS Bhol, PP Praharaj, ...
    Seminars in Cancer Biology 83, 399-412 , 2022
    2022
    Citations: 28
  • Intricate role of mitochondrial calcium signalling in mitochondrial quality control for regulation of cancer cell fate
    S Patra, KK Mahapatra, PP Praharaj, DP Panigrahi, CS Bhol, SR Mishra, ...
    Mitochondrion 57, 230-240 , 2021
    2021
    Citations: 20
  • Molecular regulation of mitophagy signaling in tumor microenvironment and its targeting for cancer therapy
    BP Behera, SR Mishra, S Patra, KK Mahapatra, CS Bhol, DP Panigrahi, ...
    Cytokine & growth factor reviews , 2025
    2025
    Citations: 18