Chun Yin Chan

@carellgroup.de

Ph.D. candidate, Department of Chemistry and Pharmacy
Ludwig Maximilian University of Munich

Chun Yin Chan


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https://researchid.co/chanjamie43
Research interest:
Prebiotic chemistry
Modified RNA
Directed evolution
SELEX
G-quadruplex
Nucleic acids

EDUCATION

2020-
Ph.D. candidate, Prof. Dr. Thomas Carell
Graduate School of Life Science Munich
Ludwig Maximilian University of Munich

2014-2018
Bachelor of Science in Applied Chemistry (1st class hon.)
City University of Hong Kong

RESEARCH, TEACHING, or OTHER INTERESTS

Biochemistry, Genetics and Molecular Biology, Chemistry
626

Scholar Citations

11

Scholar h-index

11

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Membrane bound geranylated RNAs establish a primitive peptide synthesis system
    CY Chan, J Singer, T Carell
    bioRxiv, 2024.08. 02.606298 , 2024
    2024
  • Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5′ UTR rG4 unwinding and Anp32e translation
    X Chen, G Xue, J Zhao, Y Zhang, S Zhang, W Wang, Y Li, J Yuan, L He, ...
    Cell Reports 39 (10) , 2022
    2022
    Citations: 32
  • Development of RNA G-quadruplex (rG4)-targeting l -RNA aptamers by rG4-SELEX
    MI Umar, CY Chan, CK Kwok
    Nature Protocols 17 (6), 1385-1414 , 2022
    2022
    Citations: 29
  • A prebiotically plausible scenario of an RNA–peptide world
    F Müller, L Escobar, F Xu, E Węgrzyn, M Nainytė, T Amatov, CY Chan, ...
    Nature 605 (7909), 279-284 , 2022
    2022
    Citations: 186
  • Proteomic and Transcriptome Profiling of G-Quadruplex Aptamers Developed for Cell Internalization
    Y Zhang, Y Wu, H Zheng, H Xi, T Ye, CY Chan, CK Kwok
    Analytical Chemistry 93 (14), 5744-5753 , 2021
    2021
    Citations: 17
  • Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA‐Peptide World
    M Nainytė, F Müller, G Ganazzoli, CY Chan, A Crisp, D Globisch, T Carell
    Chemistry–A European Journal 26 (65), 14856-14860 , 2020
    2020
    Citations: 28
  • Specific Binding of a d ‐RNA G‐Quadruplex Structure with an l ‐RNA Aptamer
    CY Chan, CK Kwok
    Angewandte Chemie International Edition 59 (13), 5293-5297 , 2020
    2020
    Citations: 49
  • G-quadruplex-based fluorescent turn-on ligands and aptamers: from development to applications
    MI Umar, D Ji, CY Chan, CK Kwok
    Molecules 24 (13), 2416 , 2019
    2019
    Citations: 103
  • Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures
    CY Chan, MI Umar, CK Kwok
    Chemical communications 55 (18), 2616-2619 , 2019
    2019
    Citations: 25
  • Structural analysis and cellular visualization of APP RNA G-quadruplex
    K Lyu, SB Chen, CY Chan, JH Tan, CK Kwok
    Chemical Science 10 (48), 11095-11102 , 2019
    2019
    Citations: 39
  • Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs
    KL Chan, B Peng, MI Umar, CY Chan, AB Sahakyan, MTN Le, CK Kwok
    Chemical communications 54 (77), 10878-10881 , 2018
    2018
    Citations: 51
  • A cancer cell-selective and low-toxic bifunctional heterodinuclear Pt (IV)–Ru (II) anticancer prodrug
    L Ma, X Lin, C Li, Z Xu, CY Chan, MK Tse, P Shi, G Zhu
    Inorganic Chemistry 57 (5), 2917-2924 , 2018
    2018
    Citations: 67

MOST CITED SCHOLAR PUBLICATIONS

  • A prebiotically plausible scenario of an RNA–peptide world
    F Müller, L Escobar, F Xu, E Węgrzyn, M Nainytė, T Amatov, CY Chan, ...
    Nature 605 (7909), 279-284 , 2022
    2022
    Citations: 186
  • G-quadruplex-based fluorescent turn-on ligands and aptamers: from development to applications
    MI Umar, D Ji, CY Chan, CK Kwok
    Molecules 24 (13), 2416 , 2019
    2019
    Citations: 103
  • A cancer cell-selective and low-toxic bifunctional heterodinuclear Pt (IV)–Ru (II) anticancer prodrug
    L Ma, X Lin, C Li, Z Xu, CY Chan, MK Tse, P Shi, G Zhu
    Inorganic Chemistry 57 (5), 2917-2924 , 2018
    2018
    Citations: 67
  • Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs
    KL Chan, B Peng, MI Umar, CY Chan, AB Sahakyan, MTN Le, CK Kwok
    Chemical communications 54 (77), 10878-10881 , 2018
    2018
    Citations: 51
  • Specific Binding of a d ‐RNA G‐Quadruplex Structure with an l ‐RNA Aptamer
    CY Chan, CK Kwok
    Angewandte Chemie International Edition 59 (13), 5293-5297 , 2020
    2020
    Citations: 49
  • Structural analysis and cellular visualization of APP RNA G-quadruplex
    K Lyu, SB Chen, CY Chan, JH Tan, CK Kwok
    Chemical Science 10 (48), 11095-11102 , 2019
    2019
    Citations: 39
  • Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5′ UTR rG4 unwinding and Anp32e translation
    X Chen, G Xue, J Zhao, Y Zhang, S Zhang, W Wang, Y Li, J Yuan, L He, ...
    Cell Reports 39 (10) , 2022
    2022
    Citations: 32
  • Development of RNA G-quadruplex (rG4)-targeting l -RNA aptamers by rG4-SELEX
    MI Umar, CY Chan, CK Kwok
    Nature Protocols 17 (6), 1385-1414 , 2022
    2022
    Citations: 29
  • Amino Acid Modified RNA Bases as Building Blocks of an Early Earth RNA‐Peptide World
    M Nainytė, F Müller, G Ganazzoli, CY Chan, A Crisp, D Globisch, T Carell
    Chemistry–A European Journal 26 (65), 14856-14860 , 2020
    2020
    Citations: 28
  • Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures
    CY Chan, MI Umar, CK Kwok
    Chemical communications 55 (18), 2616-2619 , 2019
    2019
    Citations: 25
  • Proteomic and Transcriptome Profiling of G-Quadruplex Aptamers Developed for Cell Internalization
    Y Zhang, Y Wu, H Zheng, H Xi, T Ye, CY Chan, CK Kwok
    Analytical Chemistry 93 (14), 5744-5753 , 2021
    2021
    Citations: 17
  • Membrane bound geranylated RNAs establish a primitive peptide synthesis system
    CY Chan, J Singer, T Carell
    bioRxiv, 2024.08. 02.606298 , 2024
    2024