MILIND CHITNIS

@wsu.ac.za

Associate Professor, Department of Paediatric Surgery
Frere Hospital, affilciated to Walter Sisulu University

MILIND CHITNIS


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https://researchid.co/asude9256
Dr Milind Chitnis is the Associate Professor and Head of the Department of Paediatric Surgery at the East London Hospital Complex, affiliated with the Walter Sisulu University in East London, South Africa. He has been the Honorary Secretary of the College of Paediatric Surgeons of South Africa for the 2020-2023 period and a member of the Council of the College of Paediatric Surgeons of South Africa for 2017-2026. He is a board member of the Global Initiative for Children’s Surgery (2020-2026) and the Honorary Secretary of the Pan African Association of Paediatric Surgeons (PAPSA) for 2023-2027. He is also a founding Trustee of the NPO- Eyabantwana for the Children- which supports the needs of the Department of Paediatric Surgery in East London. He is passionate about improving Paediatric Surgical care and training in low- and middle-income countries in general and Africa in particular.

EDUCATION

Certificate in Paediatric Surgery 2004 College of Medicine of South Africa

Master of Chirurgiae (MCh) 1989 Bombay (Mumbai) University, India
(Paediatric Surgery)

Master of Surgery (MS)
(General Surgery) 1986 University of Poona (Pune), India

Bachelor of Medicine & Bachelor
of Surgery (MBBS) 1982 University of Poona (Pune), India

RESEARCH, TEACHING, or OTHER INTERESTS

Surgery, Pediatrics
22

Scopus Publications

790

Scholar Citations

12

Scholar h-index

13

Scholar i10-index

Scopus Publications

  • GAPS phase II: development and pilot results of the global assessment in pediatric surgery, an evidence-based pediatric surgical capacity assessment tool for low-resource settings
    Yasmine Yousef, Sarah Cairo, Etienne St-Louis, Laura F. Goodman, Doulia M. Hamad, et al.
    Pediatric Surgery International, 2024
  • Machine Learning to Predict Interim Response in Pediatric Classical Hodgkin Lymphoma Using Affordable Blood Tests
    Jennifer A. Geel, Artsiom Hramyka, Jan du Plessis, Yasmin Goga, Anel Van Zyl, et al.
    JCO Global Oncology, 2024
    PURPOSE Response assessment of classical Hodgkin lymphoma (cHL) with positron emission tomography-computerized tomography (PET-CT) is standard of care in well-resourced settings but unavailable in most African countries. We aimed to investigate correlations between changes in PET-CT findings at interim analysis with changes in blood test results in pediatric patients with cHL in 17 South African centers. METHODS Changes in ferritin, lactate dehydrogenase (LDH), erythrocyte sedimentation rate (ESR), albumin, total white cell count (TWC), absolute lymphocyte count (ALC), and absolute eosinophil count were compared with PET-CT Deauville scores (DS) after two cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine in 84 pediatric patients with cHL. DS 1-3 denoted rapid early response (RER) while DS 4-5 denoted slow early response (SER). Missing values were imputed using the k-nearest neighbor algorithm. Baseline and follow-up blood test values were combined into a single difference variable. Data were split into training and testing sets for analysis using Python scikit-learn 1.2.2 with logistic regression, random forests, naïve Bayes, and support vector machine classifiers. RESULTS Random forest analysis achieved the best validated test accuracy of 73% when predicting RER or SER from blood samples. When applied to the full data set, the optimal model had a predictive accuracy of 80% and a receiver operating characteristic AUC of 89%. The most predictive variable was the differences in ALC, contributing 21% to the model. Differences in ferritin, LDH, and TWC contributed 15%-16%. Differences in ESR, hemoglobin, and albumin contributed 11%-12%. CONCLUSION Changes in low-cost, widely available blood tests may predict chemosensitivity for pediatric cHL without access to PET-CT, identifying patients who may not require radiotherapy. Changes in these nonspecific blood tests should be assessed in combination with clinical findings and available imaging to avoid undertreatment.
  • An International Consensus Survey among Pediatric Surgeons on the Role of Appendectomy in Malrotation
    Revathy Menon, Kirtikumar J. Rathod, Arvind Sinha, Ashish Minocha, Carlos Garcia Hernandez, et al.
    Journal of Indian Association of Pediatric Surgeons, 2024
    Introduction: Ladd’s procedure, originally described in 1936 for the treatment of malrotation, does not traditionally include appendectomy as a standard step. We conducted a multinational survey to investigate the current consensus on the role of appendectomy in Ladd’s procedure. Methodology: An anonymous online survey was distributed to pediatric surgeons worldwide. The survey collected demographic data and explored surgical preferences related to the management of malrotation. Open-ended questions were used to assess the opinions regarding the necessity of appendectomy, decision-making factors, and complications associated with appendectomy during Ladd’s procedure. Results: A total of 343 responses were received from 46 countries. Of the respondents, 319 (93%) were consultants and 24 (7%) were residents/trainees. When asked about the choice between open and laparoscopic Ladd’s procedure, 292 (85%) preferred open surgery. Overall, 184 (53%) respondents favored appendectomy in both open and laparoscopic Ladd’s procedure. Furthermore, 172 (50%) surgeons advocated for appendectomy in all malrotation cases, citing concerns about potential future appendicitis. While differences existed between all comparisons, none of them reached statistical significance. The factors influencing the decision to preserve the appendix included the risk of postoperative complications and the potential future use of the appendix as a surgical conduit. The surgical complications following appendectomy included surgical site infections in 14 (33%) patients, adhesive obstruction in 13 (31%) patients, intrabdominal abscesses in 10 (24%) patients, and fecal fistulas in 5 (12%) patients. Conclusion: The majority of surgeons aim to perform appendectomy in all malrotation cases, considering the potential risks and benefits of this approach. These findings offer valuable insights for clinical practice and may inform future guidelines and decision-making algorithms.
  • Trauma and sexual abuse in children—Epidemiology, challenges, management strategies and prevention in lower- and middle-income countries
    Abdelbasit E Ali, Shilpa Sharma, Olumide A Elebute, Adesoji Ademuyiwa, Noxolo Z. Mashavave, et al.
    Seminars in Pediatric Surgery, 2023
  • Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions
    SelloS Machaea, MilindR Chitnis, Phumza Nongena
    African Journal of Paediatric Surgery, 2023
    Context: Gastroschisis is a common abdominal wall defect faced by paediatric surgeons worldwide. Early gastroschisis detection, access to improved neonatal intensive care, parenteral nutrition and surgical techniques have led to a reported improvement in mortality of between 4% and 8% in high-income countries. In low to middle income countries, such as in Southern Africa, however, there is as much as 84% mortality among patients with gastroschisis. This is thought to be due to factors such as lack of antenatal screening, access to neonatal intensive care services and parenteral nutrition. Aims: The purpose of this study was to calculate the prevalence of gastroschisis and report on its neonatal mortality in the Eastern Cape Province of South Africa. Settings and Design: A retrospective observational study on all neonates with gastroschisis, presenting to a tertiary facility offering paediatric surgical services within the Eastern Cape Province from 1 January 2016 to 31 December 2018. Subjects and Methods: A convenience sampling method was used in retrieving patient files for the study period. Statistical analysis used: Stata version 13. Results: Thirty-seven neonates were included in the study. The prevalence of gastroschisis ranged from 0.07% to 0.18% throughout the 3-year study. The majority (81%) of the neonates were outborn and delivered by mode of caesarean section. Nearly 60% (n = 22) were female. 54% (n = 20) of neonates died within the neonatal period. Conclusions: The majority of the neonates in this study were outborn and female. Although their mortality rate was higher than reported in high-income countries, it was much improved from what is reported in the low to middle income countries.
  • Long proximal pouch oesophageal atresia with tracheo-oesophageal fistula, a diagnostic dilemma: case report
    Sello Machaea, Vuyo Nogela, Milind Chitnis
    Annals of Pediatric Surgery, 2022
    Background Oesophageal atresia is a congenital abnormality commonly encountered in neonates. Classification proposed by Gross is the most frequently used. It divides the oesophageal anomalies into five types. Type C—proximal oesophageal atresia and distal tracheo-oesophageal fistula—is the most common. Dafoe and Ross described a rare subtype with a long proximal pouch. Only 11 cases of a long proximal pouch have been reported in the English literature so far. We describe a neonate with long proximal pouch oesophageal atresia with distal tracheo-oesophageal fistula emphasizing the difficulty in arriving at the diagnosis. Case presentation A 1-week-old neonate presented with feed intolerance and failure to advance orogastric tube into the stomach. Water soluble upper gastrointestinal tract contrast revealed a blind ending proximal oesophagus at the level of the diaphragm. Gastric volvulus was considered as a diagnosis. Patient underwent a laparotomy where a normal stomach was found. Bubbles were seen coming from the fashioned gastrostomy with each inspiration. This prompted us to consider the possibility of a missed oesophageal atresia with distal tracheo-oesophageal fistula. Diagnosis was confirmed on bronchoscopy and right thoracotomy. The tracheo-oesophageal fistula was ligated and a cervical oesophagostomy and Stamm gastrostomy were performed due to irreparable tear in the long upper pouch. Conclusion This rare subtype of long upper pouch oesophageal atresia poses a diagnostic dilemma that can result in delay in the diagnosis and management. This diagnosis should be suspected if the tip of the orogastric/feeding tube is seen to be far below the level of the carina.
  • Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
    BMJ Global Health, 2022
    IntroductionChildhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality.MethodsProspective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months.ResultsAll-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3–11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality.ConclusionsChildren with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer.
  • Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study
    Prasanna Gomes, Jacqueline Montoya Vasquez, Daniel H Rhee, S. Cooper, Y. Kara
    BMJ Open, 2022
    ObjectivesPaediatric cancer is a leading cause of death for children. Children in low-income and middle-income countries (LMICs) were four times more likely to die than children in high-income countries (HICs). This study aimed to test the hypothesis that the COVID-19 pandemic had affected the delivery of healthcare services worldwide, and exacerbated the disparity in paediatric cancer outcomes between LMICs and HICs.DesignA multicentre, international, collaborative cohort study.Setting91 hospitals and cancer centres in 39 countries providing cancer treatment to paediatric patients between March and December 2020.ParticipantsPatients were included if they were under the age of 18 years, and newly diagnosed with or undergoing active cancer treatment for Acute lymphoblastic leukaemia, non-Hodgkin’s lymphoma, Hodgkin lymphoma, Wilms’ tumour, sarcoma, retinoblastoma, gliomas, medulloblastomas or neuroblastomas, in keeping with the WHO Global Initiative for Childhood Cancer.Main outcome measureAll-cause mortality at 30 days and 90 days.Results1660 patients were recruited. 219 children had changes to their treatment due to the pandemic. Patients in LMICs were primarily affected (n=182/219, 83.1%). Relative to patients with paediatric cancer in HICs, patients with paediatric cancer in LMICs had 12.1 (95% CI 2.93 to 50.3) and 7.9 (95% CI 3.2 to 19.7) times the odds of death at 30 days and 90 days, respectively, after presentation during the COVID-19 pandemic (p<0.001). After adjusting for confounders, patients with paediatric cancer in LMICs had 15.6 (95% CI 3.7 to 65.8) times the odds of death at 30 days (p<0.001).ConclusionsThe COVID-19 pandemic has affected paediatric oncology service provision. It has disproportionately affected patients in LMICs, highlighting and compounding existing disparities in healthcare systems globally that need addressing urgently. However, many patients with paediatric cancer continued to receive their normal standard of care. This speaks to the adaptability and resilience of healthcare systems and healthcare workers globally.
  • Clinical presentation and management of childhood intussusception in South Africa
    Sharon Cox, Aletha Withers, Marion Arnold, Milind Chitnis, Corné de Vos, et al.
    Pediatric Surgery International, 2021
    Purpose We assessed management and outcomes for intussusception at nine academic hospitals in South Africa. Methods Patients ≤ 3 years presenting with intussusception between September 2013 and December 2017 were prospectively enrolled at all sites. Additionally, patients presenting between July 2012 and August 2013 were retrospectively enrolled at one site. Demographics, clinical information, diagnostic modality, reduction methods, surgical intervention and outcomes were reviewed. Results Four hundred seventy-six patients were enrolled, [54% males, median age 6.5 months (IQR 2.6–32.6)]. Vomiting (92%), bloody stool (91%), abdominal mass (57%), fever (32%) and a rectal mass (29%) represented advanced disease: median symptom duration was 3 days (IQR 1–4). Initial reduction attempts included pneumatic reduction (66%) and upfront surgery (32%). The overall non-surgical reduction rate was 28% and enema perforation rate was 4%. Surgery occurred in 334 (70%), 68 (20%) patients had perforated bowel, bowel resection was required in 61%. Complications included recurrence (2%) and nosocomial sepsis (4%). Length of stay (LOS) was significantly longer in patients who developed complications. Six patients died—a mortality rate of 1%. There was a significant difference in reduction rates, upfront surgery, bowel resection, LOS and mortality between centres with shorter symptom duration compared longer symptom duration. Conclusion Delayed presentation was common and associated with low success for enema reduction, higher operative rates, higher rates of bowel resection and increased LOS. Improved primary health-care worker education and streamlining referral pathways might facilitate timely management.
  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
    Naomi Jane Wright, Andrew J.M. Leather, Niyi Ade-Ajayi, Nick Sevdalis, Justine Davies, et al.
    Lancet, 2021
    Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030. Funding Wellcome Trust.
  • Evaluation of intussusception after oral monovalent rotavirus vaccination in South Africa
    Michelle J Groome, Jacqueline E Tate, Marion Arnold, Milind Chitnis, Sharon Cox, et al.
    Clinical Infectious Diseases, 2020
  • Global Initiative for Children’s Surgery: A Model of Global Collaboration to Advance the Surgical Care of Children
    Naomi Wright, Guy Jensen, Etienne St‐Louis, David Grabski, Yasmine Yousef, et al.
    World Journal of Surgery, 2019
  • Optimal Resources for Children’s Surgical Care: Executive Summary
    David Grabski, Emmanuel Ameh, Doruk Ozgediz, Keith Oldham, Francis A. Abantanga, et al.
    World Journal of Surgery, 2019
  • Laparoscopically inserted button colostomy as a venting stoma and access port for the administration of antegrade enemas in African degenerative leiomyopathy
    South African Journal of Surgery, 2011
  • Retrospective surveillance of intussusception in South Africa, 1998-2003
    S. W. Moore, M. Kirsten, E. W. Müller, A. Numanoglu, M. Chitnis, et al.
    Journal of Infectious Diseases, 2010
  • The spectrum of anorectal malformations in Africa
    S. W. Moore, A. Alexander, D. Sidler, J. Alves, G. P. Hadley, et al.
    Pediatric Surgery International, 2008
  • Hepatocellular carcinoma and liver tumors in South African children: A case for increased prevalence
    Samuel W. Moore, Alistair J. W. Millar, G. P. (Larry) Hadley, Gabriel Ionescu, Mariana Kruger, et al.
    Cancer, 2004
  • Preoperative angioembolisation for life-threatening haemorrhage from Wilms' tumour: A case report
    M. Chitnis, S.K. Chowdhary, C. Lazarus
    Pediatric Surgery International, 2004
  • Differentiation of a benign myxolipoma from a myxoid liposarcoma by tumour karyotyping - A diagnosis missed
    Pediatric Surgery International, 2002
  • Application of the Malone antegrade continence enema principle in degenerative leiomyopathy
    M. Chitnis, S. Chowdhary, C. Lazarus
    Pediatric Surgery International, 2001
  • Pediatric Parenteral Nutrition: South African Model and its Relevance to the Developing Countries
    Indian Pediatrics, 2000
  • Hypothyroldism in a neonate following excision of a cervical teratoma
    S. K. Chowdhary, M. Chitnis, J. Perold, C. Lazarus
    Pediatric Surgery International, 1998

RECENT SCHOLAR PUBLICATIONS

  • SECRET-IBD: multi-centre retrospective cohort study on oncological outcome of Inflammatory Bowel Disease patients who have undergone segmental colectomy for cancer and …
    A Shamsiddinova, W Ramadan, M Chitnis, O Argyriou, S Davey, EA Patel, ...
    European Journal of Surgical Oncology 50 , 2024
    2024
  • GAPS phase II: development and pilot results of the global assessment in pediatric surgery, an evidence-based pediatric surgical capacity assessment tool for low-resource settings
    Y Yousef, S Cairo, E St-Louis, LF Goodman, DM Hamad, R Baird, ...
    Pediatric Surgery International 40 (1), 158 , 2024
    2024
    Citations: 3
  • An international consensus survey among pediatric surgeons on the role of appendectomy in malrotation
    R Menon, KJ Rathod, A Sinha, A Minocha, CG Hernandez, D Jiang, ...
    Journal of Indian Association of Pediatric Surgeons 29 (3), 256-260 , 2024
    2024
    Citations: 3
  • GAPS II: Development and Pilot Results of the Global Assessment in Pediatric Surgery, an Evidence-Based Pediatric Surgical Capacity Assessment Tool for Low-Resource Settings
    Y Yousef, S Cairo, E St-Louis, LF Goodman, DM Hamad, R Baird, ...
    2024
  • Trauma and sexual abuse in children—Epidemiology, challenges, management strategies and prevention in lower-and middle-income countries
    AE Ali, S Sharma, OA Elebute, A Ademuyiwa, NZ Mashavave, M Chitnis, ...
    Seminars in Pediatric Surgery 32 (6), 151356 , 2023
    2023
    Citations: 4
  • Microorganisms detected in intussusception cases and controls in children< 3 years in South Africa from 2013 to 2017
    NA Page, R Netshikweta, JE Tate, SA Madhi, UD Parashar, MJ Groome, ...
    Open Forum Infectious Diseases 10 (9), ofad458 , 2023
    2023
    Citations: 2
  • Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions
    SS Machaea, MR Chitnis, P Nongena
    African Journal of Paediatric Surgery 20 (1), 46-50 , 2023
    2023
    Citations: 10
  • Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
    S Bandyopadhyay, N Peter, K Lakhoo, SCV Abib, H Abdelhafeez, ...
    BMJ Global Health 7 (10) , 2022
    2022
    Citations: 8
  • Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study
    Global Health Research Group on Children’s Non-Communicable Diseases ...
    BMJ open 12 (4), e054690 , 2022
    2022
    Citations: 16
  • Long proximal pouch oesophageal atresia with tracheo-oesophageal fistula, a diagnostic dilemma: case report
    S Machaea, V Nogela, M Chitnis
    Annals of Pediatric Surgery 18 (1), 15 , 2022
    2022
  • Clinical presentation and management of childhood intussusception in South Africa
    S Cox, A Withers, M Arnold, M Chitnis, C De Vos, M Kirsten, ...
    Pediatric Surgery International 37 (10), 1361-1370 , 2021
    2021
    Citations: 21
  • Paediatric surgical outcomes in sub-Saharan Africa: a multicentre, international, prospective cohort study
    NJ Wright, ER Smith, A Bisquera, AL John-Chukwuemeka, TA Lawal, ...
    BMJ global health 6 (9) , 2021
    2021
    Citations: 47
  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective …
    NJ Wright, AJM Leather, N Ade-Ajayi, N Sevdalis, J Davies, D Poenaru, ...
    The Lancet 398 (10297), 325-339 , 2021
    2021
    Citations: 168
  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-, middle-and high-income countries: a multicentre, international, prospective cohort study
    N Hall, N Wright
    The Lancet , 2021
    2021
    Citations: 1
  • Evaluation of intussusception after oral monovalent rotavirus vaccination in South Africa
    MJ Groome, JE Tate, M Arnold, M Chitnis, S Cox, C De Vos, M Kirsten, ...
    Clinical Infectious Diseases 70 (8), 1606-1612 , 2020
    2020
    Citations: 43
  • Global initiative for children’s surgery: a model of global collaboration to advance the surgical care of children
    Global Initiative for Children’s Surgery, N Wright, G Jensen, E St‐Louis, ...
    World Journal of Surgery 43 (6), 1416-1425 , 2019
    2019
    Citations: 68
  • Optimal resources for children’s surgical care: executive summary
    World Journal of Surgery 43 (4), 978-980 , 2019
    2019
    Citations: 53
  • The global initiative for children's surgery: optimal resources for improving care
    LF Goodman, E St-Louis, Y Yousef, M Cheung, B Ure, D Ozgediz, ...
    European Journal of Pediatric Surgery 28 (01), 051-059 , 2018
    2018
    Citations: 114
  • Bronchoscopic removal of aspirated foreign bodies: an essential skill for a paediatric surgeon working in the developing world
    M Chitnis, D von Delft, R Spence, C Lazarus
    Bangladesh Journal of Endosurgery 1 (1), 4-8 , 2013
    2013
    Citations: 2
  • Laparoscopically inserted button colostomy as a venting stoma and access port for the administration of antegrade enemas in African degenerative leiomyopathy
    M Chitnis, C Lazarus, I Simango, M Elsen, C Van Rensburg, D Von Delft, ...
    South African Journal of Surgery 49 (1), 44-46 , 2011
    2011
    Citations: 5

MOST CITED SCHOLAR PUBLICATIONS

  • Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective …
    NJ Wright, AJM Leather, N Ade-Ajayi, N Sevdalis, J Davies, D Poenaru, ...
    The Lancet 398 (10297), 325-339 , 2021
    2021
    Citations: 168
  • The global initiative for children's surgery: optimal resources for improving care
    LF Goodman, E St-Louis, Y Yousef, M Cheung, B Ure, D Ozgediz, ...
    European Journal of Pediatric Surgery 28 (01), 051-059 , 2018
    2018
    Citations: 114
  • The spectrum of anorectal malformations in Africa
    SW Moore, A Alexander, D Sidler, J Alves, GP Hadley, A Numanoglu, ...
    Pediatric surgery international 24 (6), 677-683 , 2008
    2008
    Citations: 72
  • Global initiative for children’s surgery: a model of global collaboration to advance the surgical care of children
    Global Initiative for Children’s Surgery, N Wright, G Jensen, E St‐Louis, ...
    World Journal of Surgery 43 (6), 1416-1425 , 2019
    2019
    Citations: 68
  • Hepatocellular carcinoma and liver tumors in South African children: a case for increased prevalence
    SW Moore, AJW Millar, GP Hadley, G Ionescu, M Kruger, J Poole, ...
    Cancer: Interdisciplinary International Journal of the American Cancer … , 2004
    2004
    Citations: 68
  • Optimal resources for children’s surgical care: executive summary
    World Journal of Surgery 43 (4), 978-980 , 2019
    2019
    Citations: 53
  • Retrospective surveillance of intussusception in South Africa, 1998–2003
    SW Moore, M Kirsten, EW Muüller, A Numanoglu, M Chitnis, E Le Grange, ...
    Journal of infectious diseases 202 (Supplement_1), S156-S161 , 2010
    2010
    Citations: 49
  • Paediatric surgical outcomes in sub-Saharan Africa: a multicentre, international, prospective cohort study
    NJ Wright, ER Smith, A Bisquera, AL John-Chukwuemeka, TA Lawal, ...
    BMJ global health 6 (9) , 2021
    2021
    Citations: 47
  • Evaluation of intussusception after oral monovalent rotavirus vaccination in South Africa
    MJ Groome, JE Tate, M Arnold, M Chitnis, S Cox, C De Vos, M Kirsten, ...
    Clinical Infectious Diseases 70 (8), 1606-1612 , 2020
    2020
    Citations: 43
  • Clinical presentation and management of childhood intussusception in South Africa
    S Cox, A Withers, M Arnold, M Chitnis, C De Vos, M Kirsten, ...
    Pediatric Surgery International 37 (10), 1361-1370 , 2021
    2021
    Citations: 21
  • Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study
    Global Health Research Group on Children’s Non-Communicable Diseases ...
    BMJ open 12 (4), e054690 , 2022
    2022
    Citations: 16
  • Preoperative angioembolisation for life-threatening haemorrhage from Wilms’ tumour: a case report
    M Chitnis, SK Chowdhary, C Lazarus
    Pediatric Surgery International 20 (4), 290-291 , 2004
    2004
    Citations: 15
  • Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions
    SS Machaea, MR Chitnis, P Nongena
    African Journal of Paediatric Surgery 20 (1), 46-50 , 2023
    2023
    Citations: 10
  • Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
    S Bandyopadhyay, N Peter, K Lakhoo, SCV Abib, H Abdelhafeez, ...
    BMJ Global Health 7 (10) , 2022
    2022
    Citations: 8
  • Hypothyroldism in a neonate following excision of a cervical teratoma
    SK Chowdhary, M Chitnis, J Perold, C Lazarus
    Pediatric surgery international 14 (3), 212-213 , 1998
    1998
    Citations: 8
  • Application of the Malone antegrade continence enema principle in degenerative leiomyopathy
    M Chitnis, S Chowdhary, C Lazarus
    Pediatric surgery international 17 (5), 470-471 , 2001
    2001
    Citations: 6
  • Laparoscopically inserted button colostomy as a venting stoma and access port for the administration of antegrade enemas in African degenerative leiomyopathy
    M Chitnis, C Lazarus, I Simango, M Elsen, C Van Rensburg, D Von Delft, ...
    South African Journal of Surgery 49 (1), 44-46 , 2011
    2011
    Citations: 5
  • Trauma and sexual abuse in children—Epidemiology, challenges, management strategies and prevention in lower-and middle-income countries
    AE Ali, S Sharma, OA Elebute, A Ademuyiwa, NZ Mashavave, M Chitnis, ...
    Seminars in Pediatric Surgery 32 (6), 151356 , 2023
    2023
    Citations: 4
  • GAPS phase II: development and pilot results of the global assessment in pediatric surgery, an evidence-based pediatric surgical capacity assessment tool for low-resource settings
    Y Yousef, S Cairo, E St-Louis, LF Goodman, DM Hamad, R Baird, ...
    Pediatric Surgery International 40 (1), 158 , 2024
    2024
    Citations: 3
  • An international consensus survey among pediatric surgeons on the role of appendectomy in malrotation
    R Menon, KJ Rathod, A Sinha, A Minocha, CG Hernandez, D Jiang, ...
    Journal of Indian Association of Pediatric Surgeons 29 (3), 256-260 , 2024
    2024
    Citations: 3

Publications

Abdelbasit E Ali, Shilpa Sharma, Olumide A Elebute, Adesoji Ademuyiwa, Noxolo Z. Mashavave, Milind Chitnis, Simone Abib, Fazal Nouman Wahid Trauma and sexual abuse in children—Epidemiology, challenges, management strategies and prevention in lower and middle-income countries Seminars in Pediatric Surgery Volume 32, Issue 6, December 2023,
151356

• Machaea SS, Chitnis MR, Nongena P. Prevalence of gastroschisis and its neonatal mortality in the Eastern Cape Province tertiary institutions. Afr J Paediatr Surg 2023; 20:46-50 DOI: 10.4103/


• Evaluation of Intussusception After Oral Monovalent Rotavirus Vaccination in South Africa
Michelle J Groome, Jacqueline E Tate, Marion Arnold, Milind Chitnis, Sharon Cox, Corné de Vos, Mari Kirsten, Susanna M le Grange, Jerome Loveland, Sello Machaea,
Ashwini Maharaj, Nick Andrews, Shabir A Madhi, Umesh D Parashar
Clinical Infectious Diseases, ciz431,
• Collaborating author: Global Initiative for Children’s Surgery: A Model of Global Collaboration to Advance the Surgical Care of Children World Journal of Surgery
June 2019, Volume 43, Issue 6, pp 1416–1425
doi: 10.1007/s00268-018-04887-8.

• Chitnis M, Lazarus C, Simango I, Elsen M, von Delft D, van Rensburg C, Tovell Trollope L. Laparoscopically inserted button col

Industry, Institute, or Organisation Collaboration

Pan African Paediatric Surgical Association
Global Initiative for Children's Surgery
South African Association of Paediatric Surgeons
Eyabantwan for the Children Trust

INDUSTRY EXPERIENCE

Paediatric Surgery- clinical and training