Karina Maria Salvatore de Freitas

@uninga.br

Professor, Department of Orthodontics
Uninga University Center



                 

https://researchid.co/karinafreitas

EDUCATION

DDS, MSc, PhD, Bauru Dental School, University of São Paulo

RESEARCH INTERESTS

Dentistry, Orthodontics, Dentofacial Orthopedics

148

Scopus Publications

4504

Scholar Citations

35

Scholar h-index

97

Scholar i10-index

Scopus Publications

  • Comparison of the efficiency of initial dental alignment with Invisalign® aligners changed every 7 or 14 days in mature adults: Randomized clinical trial
    Tiago Fialho, Karina Maria Salvatore de Freitas, Eduardo Terumi Blatt Ohira, José Eduardo Prado de Souza, Renata Cristina Gobbi de Oliveira, Ricardo César Gobbi de Oliveira, Fabrício Pinelli Valarelli, Célia Regina Maio Pinzan‐Vercelino, and Paula Cotrin

    Wiley
    AbstractObjectiveTo compare the anterior crowding correction after sequential use of the first 5 aligners between two aligner exchange protocols (7 and 14 days) in mature adult patients.Materials and MethodsThirty‐six patients over 35 years who received orthodontic treatment with Invisalign® were randomly allocated to two different aligner replacement sequence protocols: Group 1: exchange every 7 days (n = 18); and Group 2: exchange every 14 days (n = 18). All patients were scanned with iTero Element 5D® (Align Technology) in two treatment times: at pre‐treatment (T1) and after using the first five aligners (T2). Little's Irregularity Index (LII) and arch widths were evaluated with OrthoCAD software. Intra and intergroup comparisons were performed with the dependent and independent t‐tests. The results were considered significant for P < .05.ResultsThirty‐five patients completed the study. Both groups' maxillary and mandibular Irregularity Indexesi were significantly lower at T2. There was no significant difference in inter‐canine, inter‐premolar, and intermolar distances. G2 (14 days) presented a greater decrease in mandibular irregularity than G1 (7 days).ConclusionBoth exchange protocols (7 and 14 days) effectively correct anterior crowding in the initial phase of orthodontic treatment with aligners in mature adult patients. However, the 14‐day exchange protocol provided a greater correction in mandibular anterior crowding in the evaluated period than the 7‐day exchange protocol.

  • Ozonated Water Promotes in vitro Decontamination of Dental Implants Surface
    Renato Bitencourt Rosado, Eder José Cruz, Thainá Pinheiro de Souza, Karina Maria Salvatore Freitas, Mariana Aparecida Lopes Ortiz, and Samira Salmeron

    Informa UK Limited

  • Comparison of Gingival Recession of Mandibular Incisors of Class III Patients Immediately after Compensatory or Surgical Orthodontic Treatment
    Fábio Jorge Saab, Daniel Salvatore de Freitas, Paula Cotrin, Renata Cristina Oliveira, Fabricio Pinelli Valarelli, Ricardo Cesar Gobbi de Oliveira, Samira Salmeron, Célia Regina Maio Pinzan Vercelino, and Karina Maria Salvatore Freitas

    Georg Thieme Verlag KG
    Abstract Objective This study aimed to compare gingival recession in mandibular anterior teeth in patients with Class III malocclusion, immediately after compensatory or surgical orthodontic treatment. Materials and Methods The sample consisted of 40 patients with Class III malocclusion, divided into two groups: Group 1 (compensatory), 20 patients treated with compensatory orthodontics, with a mean initial age of 20.26 years (standard deviation [SD] . = 7.44), mean final age of 23.07 years (SD = 7.32), and mean treatment time of 2.81 years (SD =0.84). Group 2 (surgical), who undergone orthodontic–surgical treatment, with a mean initial age of 23.08 years (SD =5.48), mean final age of 25.43 years (SD =5.12), and mean treatment time of 2.35 years (SD =1.56). Intraoral photographs taken before and after removal of the fixed orthodontic appliance were used to measure the gingival recession, from the cervical of the mandibular incisors from the most cervical point of the gingival margin to the cementoenamel junction. In the initial and final cephalograms, the position of the mandibular incisors was measured. The intergroup comparison was performed using the independent t-test. Results The results showed that there was no statistically significant difference in the gingival recession at the beginning, at the end, and of changes with treatment between the compensatory and surgical groups. Conclusion It was concluded that the compensatory and surgical orthodontic treatments for Class III malocclusion showed similar results regarding the gingival recession of the mandibular incisors.

  • Evaluation of the attractiveness of lips with different volumes after filling with hyaluronic acid
    Paula Martins de Queiroz Hernandez, Paula Cotrin, Fabricio Pinelli Valarelli, Ricardo Cesar Gobbi de Oliveira, Carina Gisele Costa Bispo, Karina Maria Salvatore Freitas, Renata Cristina Oliveira, and Dra. Paula Cotrin

    Springer Science and Business Media LLC
    AbstractTo compare the attractiveness of lips with different volumes after filling in the view of laypersons, dentists, and specialists. The sample comprised close-up frontal and lateral photographs of the lips of 16 women who underwent lip filling procedure with hyaluronic acid and was divided into 2 groups. Group 1: eight women with thinner lips at pretreatment. Group 2: eight female patients with thicker lips at pretreatment. Photographs from before and 10 days after lip filling were used to assess attractiveness randomly displayed in a Google Forms questionnaire and then sent via a messaging app to the evaluators. The evaluators' groups were general dentists, dentists with degrees in facial aesthetics, and laypersons. The attractiveness was evaluated with scores from 0 to 10 (0: least attractive and 10 the greatest). T-tests were used for the statistical comparisons. The group with thinner lips showed significantly improved attractiveness after filling. The group with thicker lips showed a worsening attractiveness after filling. The group with thicker lips had significantly higher attractiveness scores than those with thinner lips. There was no significant difference in the preference between men and women. The group of laypersons was more rigorous, giving significantly lower lip attractiveness scores. Thinner lips showed a significant improvement in attractiveness after filling. Thicker lips showed a worsening of the attractiveness score after filling. Before and after filling, thicker lips had significantly higher attractiveness scores than thinner lips.Clinical relevance: The amount of fillers applied to each patient must be individually evaluated.

  • Incisor irregularity and dental arch dimensions changes in subjects with different severity of anterior crowding: a 37-year follow-up
    Caroline Martins Gambardela-Tkacz, Gabriela Alcaraz, Paula Cotrin, Karina Maria Salvatore de Freitas, Willana Moura, Guilherme Janson, Daniela Garib, and Marcos Roberto de Freitas

    Springer Science and Business Media LLC
    Abstract Background Occlusal stability is one of the goals of orthodontic treatment, and keeping teeth aligned in the long term is a challenge for the orthodontist. This study aimed to compare the long-term incisors irregularity and dental arches dimensions changes in subjects treated with 4 premolar extractions with different pretreatment Little's irregularity index (LII). The knowledge of long-term outcomes is evidence-based information for the prognosis of future treatments. Methods In total, 41 treated subjects were divided into two groups according to mandibular Little irregularity value at pretreatment (mild or severe). The maxillary and mandibular LII, transversal, and longitudinal widths were assessed at pretreatment, posttreatment, and 37-year posttreatment. Chi-square and independent t tests were used for intergroup comparison. Results The groups presented similar behavior for all stages of maxillary and mandibular arch dimensions changes. Maxillary irregularity was corrected in both groups after treatment, and the alignment was acceptable in the long term. In the mild group, the mandibular incisor irregularity returned to pretreatment values in the long term. The mandibular LII increased in the severe group but did not return to pretreatment values in the long term. Conclusions The mild crowding group presented proportionally more relapse of mandibular incisor irregularity than the severe crowding group in the long term. Even so, the correction of mild and severe crowding with the extraction of 4 premolars showed satisfactory results in the long term, even with the presence of maturational changes and relapse.

  • Maternal Risk Factors Associated with Negative COVID-19 Outcomes and Their Relation to Socioeconomic Indicators in Brazil
    Helena Fiats Ribeiro, Maria Dalva de Barros Carvalho, Fernando Castilho Pelloso, Lander dos Santos, Marcela de Andrade Pereira Silva, Kely Paviani Stevanato, Deise Helena Pelloso Borghesan, Isaac Romani, Vlaudimir Dias Marques, Karina Maria Salvatore de Freitas,et al.

    MDPI AG
    Background: This study aimed to analyze maternal risk factors associated with negative outcomes of COVID-19 and association with socioeconomic indicators in Brazil. Methods: A cross-sectional study, with data from the Influenza Epidemiological Surveillance Information System (SIVEP-Flu) of pregnant women with COVID-19 and cases of hospitalization and death. For the analysis of risk factors and outcomes, the multiple logistic regression method was used. Results: Pregnant women who had some risk factor represented 47.04%. The chance of death was 2.48 times greater when there was a risk factor, 1.55 for ICU admission and 1.43 for use of ventilatory support. The percentage of cure was 79.64%, 15.46% without any negative outcome, 4.65% death and 0.26% death from other causes. Pregnant women who did not take the vaccine represented 30.08%, 16.74% took it and 53.18% were not specified. The variables HDI, illiteracy, per capita income and urbanization did not influence the cases of COVID-19. Conclusions: Factors such as age, obesity, asthma and pregnancy were responsible for the increase in hospitalizations, respiratory complications and death. Vaccination reduced the risk of negative outcomes by 50%. There were no correlations between socioeconomic indicators and the negative outcomes of COVID-19 in pregnant women.

  • Authors’ response
    Cinthya Nogueira and Karina de Freitas

    Elsevier BV

  • Mandibular asymmetry retreatment with minimal presurgical orthodontic preparation and fully customized lingual orthodontics: A case report with new possibilities using blender open-source software
    Pedro Graziani Olímpio Pereira, Silvio Augusto Bellini-Pereira, Demi Dahás, Denis Pimenta e Souza, Karina Maria Salvatore Freitas, and Guilherme Janson

    Elsevier BV

  • Incisors’ bone height and inclination changes after orthodontic treatment with a self-ligating passive system
    C. Pinzan-Vercelino, K. Freitas, M. Secco, A. Pinzan, P. Cotrin, F. Valarelli, G. Janson, and M. Freitas

    Medicina Oral, S.L.
    Background This study aimed to evaluate changes in the alveolar buccal bone height of maxillary and mandibular incisors after orthodontic treatment with a self-ligating passive system and to assess the correlation between bone height and incisor inclination. Material and Methods Pre (T1) and post-treatment (T2) cone-beam computed tomography images of patients treated with the Damon 3MX appliance system were measured to quantify the alveolar buccal bone height of the maxillary incisors. The incisor’s inclination was measured in digital models. Paired t-test was used to evaluate the changes between T1 and T2, and Pearson’s coefficient was used to test the correlation. Results All teeth presented statistically significant alveolar buccal bone loss at T2. A statistically significant buccal inclination was observed only for the lower left lateral incisors. There was no correlation between bone height changes and incisor inclination. Conclusions Orthodontic treatment with a self-ligating passive system showed changes in alveolar height, but these changes were not correlated with incisor inclination. Key words:Passive self-ligating brackets, orthodontics, corrective, treatment outcome, alveolar bone loss.

  • Influence of the third molar presence on the thickness and height of the buccal cortical bone of the mandibular first and second molars
    PM. Pinheiro, K. Freitas, and R. de Castro

    Medicina Oral, S.L.
    Background This study aimed to evaluate the influence of the presence of the third molars on the thickness and height of the buccal cortical bone of the first and second mandibular molars. Material and Methods The retrospective cross-sectional observational sample consisted of 102 CBCTs of patients (mean age of 29 years), divided into two groups: G1: 51 patients (26 female; 25 male, mean age of 26 years) presenting the mandibular third molars and G2: 51 patients (26 female; 25 male, mean age of 32 years) with the absence of the mandibular third molars. The total and the cortical depth were evaluated at 4 and 6mm from the cementoenamel junction (CEJ). The total thickness of the buccal bone was evaluated in two horizontal reference lines located apically 6 mm and 11 mm from the CEJ. Statistical comparisons were performed with Mann Whitney and Wilcoxon tests. Results In the comparison of buccal bone thickness and height between the groups, there was a statistical difference in tooth 36. In tooth 37 there was a statistical difference in the mesial root. For tooth 47, there was a statistical difference for the total thickness at 6mm, 11mm and 4mm. Concerning age, there was a tendency to decrease the values of these variables with increasing age. Conclusions The mean values for buccal bone thickness, total and cortical depth of the mandibular molars were higher for patients with mandibular third molars because the buccal bone thickness of the mandibular molars increased in the posterior and apical direction. Key words:Molar tooth, jaw, bone, orthodontic anchorage procedures, cone-beam computed tomography.

  • Correlation of age and skeletal effects after miniscrew assisted rapid palatal expansion
    C. Marín, Md. Benitez, A. Otazu, D. Torres, P. Cotrin, C. Pinzan-Vercelino, F. Valarelli, and K. Freitas

    Medicina Oral, S.L.
    Background To evaluate the skeletal and dentoalveolar effects after miniscrew assisted rapid palatal expansion (MARPE) and their correlation with the age of the patients. Settings and sample population: Sample comprised 19 patients with maxillary atresia and posterior crossbite, treated with MARPE. Cone-beam computed tomographs (CBCT) were evaluated before and after expansion. Three patients were excluded since the midpalatal suture was not opened. Thus, 16 patients (11 female; 5 male) were evaluated, with a mean age of 24.92 years (s.d.=7.60). The time between the installation of MARPE and the second CBCT was, on average, 1.64 months (s.d.=1.12). Material and Methods Linear and angular measurements were performed: bone thickness and level, tooth inclination, transverse dental widths, and nasal base and jugula widths. Comparison was performed with dependent t-test and correlations with Pearson coefficient. Results MARPE was 84.2% successful. There was significant reduction in the buccal bone thickness of the first molars and an increase in the palatal bone thickness of all teeth. First molars showed significant buccal inclination. All transverse dimensions showed a significant increase. Older patients tended to show a less maxillary transverse skeletal increase. A greater maxillary transverse increase was accompanied by a greater intermolar width increase and also a greater buccal bone loss in the mesiobuccal roots of the maxillary first molars. Conclusions MARPE corrected the maxillary atresia in adult patients, with significant transverse increases, a slight decrease in buccal bone thickness and buccal inclination of the first molars, combining skeletal and dental effects. Older patients presented less transverse skeletal increases. Key words:Palatal expansion technique, skeletal anchorage, cone-beam computed tomography.

  • Authors’ response
    Rosangela Colet, Paula Cotrin, Fabrício Pinelli Valarelli, and Karina Maria Salvatore Freitas

    Elsevier BV

  • Evaluation of enamel deproteinization in bond strength of orthodontic accessories: A split-mouth randomized clinical trial
    Renan Morais Peloso, Paula Cotrin, Renata Cristina Gobbi de Oliveira, Ricardo César Gobbi de Oliveira, Fabricio Pinelli Valarelli, and Karina Maria Salvatore Freitas

    Elsevier BV

  • Gingival recession in mandibular anterior teeth in patients with Class II malocclusion treated with elastics and Twin Force appliance
    Rosangela Colet, Paula Cotrin, Renata Cristina Oliveira, Fabricio Pinelli Valarelli, Ricardo Cesar Gobbi de Oliveira, Samira Salmeron, and Karina Maria Salvatore Freitas

    Elsevier BV

  • Authors’ response
    Roberta Caetano Calil, Fabricio Pinelli Valarelli, and Karina Maria Salvatore Freitas

    Elsevier BV

  • Low-Level Laser and Antimicrobial Photodynamic Therapy Reduce Peri-implantitis-related Microorganisms Grown in Vitro
    Marcelo H. Tonin, Fabiano C. Brites, José R. Mariano, Karina M. S. Freitas, Mariana A. L. Ortiz, and Samira Salmeron

    Georg Thieme Verlag KG
    Abstract Objective Currently, dental implants are a predictable treatment option for oral rehabilitation; however, complications such as peri-implant diseases are increasing every day. Thus, the aim of this study was to verify the efficacy, in vitro, of two protocols against cultures of periodontal biofilm and Staphylococcus aureus. Material and Methods Petri dishes for each of the following groups were used: control groups (C)—plates inoculated with periodontal biofilm (C.B; n = 4) or S. aureus (C.SA; n = 4) without any treatment; laser groups—plates inoculated with periodontal biofilm (low-level laser therapy [LLLT].B; n = 4) or S. aureus (LLLT.SA; n = 4) and treated with LLLT (660 nm, 30 mW, 50 J/cm2, and 47 seconds); antimicrobial photodynamic therapy groups (aPDT)—plates inoculated with periodontal biofilm (aPDT.B; n = 4) or S. aureus (aPDT.SA; n = 4) and treated with aPDT (red laser 660 nm, 30 mW, 50 J/cm2, 47 seconds + toluidine blue O (TBO) 100 µg/mL, and 1 minute). After treatments were performed, the contents of all plates were diluted and seeded for counting colony-forming units (CFUs). Statistical Analysis Results were analyzed with one-way analysis of variance (ANOVA), Tukey’s test, comparison of percentages, and independent t-tests with a 5% significance level. Results Both treatments, LLLT and aPDT, significantly reduced the number of CFUs for the two types of culture, LLLT.B (3.69 × 106 ± 0.20), aPDT.B (2.79 × 106 ± 0.13), LLLT.SA (4.10 × 106 ± 0.12), and aPDT.SA (3.23 × 106 ± 0.10) when compared with control groups C.B (5.18 × 106 ± 0.43) and C.SA (5.81 × 106 ± 0.16; p = 0.000). When treatment groups were compared separately, there was also a statistically significant difference (p = 0.000). None of the protocols were able to eliminate cultured microorganisms. Conclusion The LLLT and aPDT protocols effectively reduced cultures of periodontal biofilm and S. aureus in vitro, with the superiority of aPDT.

  • Class II treatment effects with fixed functional appliances: Jasper jumper vs. Forsus fatigue resistant device
    Daniela Cubas Pupulim, José Fernando Castanha Henriques, Karina Maria Salvatore Freitas, Fernanda Pinelli Henriques Fontes, and Thais Maria Freire Fernandes

    Orthodontics and Craniofacial Research Wiley
    OBJECTIVE This study aimed to compare cephalometric changes of Class II malocclusion patients treated with Jasper Jumper and Forsus, associated with fixed appliances. METHODS The sample consisted of 62 individuals divided into 3 groups: group 1 included 22 subjects with a mean initial age of 12.39 years, treated with Jasper Jumper associated with fixed appliances for a mean period of 2.43 years; group 2 included 19 subjects with a mean initial age of 12.43 years, treated with Forsus associated with fixed appliances for a mean period of 3.54 years; and group 3 included 22 Class II malocclusion untreated subjects at a mean age of 12.14 years, followed for a mean period of 1.78 years. Intergroup comparison was performed with one-way ANOVA, followed by Tukey test. RESULTS Both treated groups had similar dentoskeletal changes: restrictive effect on the maxilla; clockwise rotation of the occlusal plane; mild increase in lower anterior facial height; limitation on the vertical development of the maxillary molars; labial tipping and intrusion of the mandibular incisors; extrusion of mandibular molars; improvements of the maxillomandibular relationship, overjet, overbite, molar relationship; and retrusion of the upper lip. The mandibular incisors exhibited greater protrusion in group 1 compared to the other groups. In addition, group 2 presented mild protrusion of the lower lip, and groups 1 and 3 showed mild retrusion. CONCLUSION The Jasper Jumper and Forsus appliances were effective and showed similar changes in the treatment of Class II malocclusion.

  • Preliminary Histological Evaluation of the Application of Ozone in the First Days of Orthodontic Force Induction in Animal Model
    Melissa Faccini, Felipe Agostini, Tassio Drieu, Francisco Ubiratan Ferreira de Campos, Aguinaldo Garcez, Glauber Fabre Carinhena, Samira Salmeron, Ana Regina Casaroto, Fabricio Pinelli Valarelli, and Karina Maria Salvatore Freitas

    Georg Thieme Verlag KG
    Abstract Objectives The aim of the study is to histologically evaluate the effect of ozone therapy on orthodontic force induction in an animal model. Materials and Methods Twenty-four Wistar rats were divided into three groups (n = 8). A NiTi coil spring was installed from the maxillary first molar to the maxillary central incisor. G1 was control and G2/G3 received 1 mL of ozonated gas at concentrations of 10 and 60 µg/mL, in the buccal mucosa above the first molar roots. The animals were euthanized 3 and 5 days after the procedure. Histological sections were obtained, longitudinally of the first molar’ long axis, in the mesiodistal direction. The number of osteoclasts, osteoblasts, blood vessels, polymorphonuclear and mononuclear cells, formation of osteoid tissue and hyaline areas, and root resorption were evaluated with light microscope, in tension and pressure sides. Intergroup comparisons were performed with Kruskal–Wallis, Dunn, and Chi-square tests. Results At 3-days pressure side, a greater number of osteoclasts was observed in ozone groups and greater number of blood vessels and polymorphonuclear cells were observed in G2. On the tension side, there was a significantly greater number of blood vessels, osteoblasts, and mononuclear cells in G2. At 5-days pressure side, there was a significantly greater number of osteoclasts in G2, blood vessels and osteoblasts in the ozone groups, and lesser number of polymorphonuclear cells in G3. Conclusion Ozone therapy increased the number of osteoclasts on the pressure side and osteoblasts on tension side, in 10 µg/mL concentration, demonstrating histological parameters favorable to bone remodeling. The 60 µg/mL ozone concentration accelerated the periodontal ligament reorganization process.

  • Profile changes after class II treatment with twin force appliance in patients with different facial patterns
    Lucimar Schimmack Pedro, Karina Maria Salvatore Freitas, Adriano Garcia Bandeca, Renata Cristina Oliveira, Ricardo Gobbi Oliveira, Fabrício Pinelli Valarelli, Paula Cotrin, and Rodrigo Hermont Cançado

    Informa UK Limited

  • Efficacy of products for bleaching and whitening under orthodontic brackets
    Célia Regina Maio PINZAN-VERCELINO, Suellen Nogueira Linares LIMA, Fernando Félix de Jesus Vieira PEREIRA, Júlio de Araújo GURGEL, Gisele Rodrigues da SILVA, and Karina Maria Salvatore de FREITAS

    FapUNIFESP (SciELO)
    ABSTRACT Introduction: Many patients wearing orthodontic appliances request alterations in the shade of their teeth during orthodontic treatment. Objective: This study aimed to evaluate the efficacy of different products for bleaching and whitening under orthodontic brackets. Methods: Seventy bovine incisors were randomly divided into five groups (n = 14): C) non-whitening toothpaste (control); WTsi) hydrated silica whitening toothpaste; WThp) 2% hydrogen peroxide whitening toothpaste; OB) in-office bleaching; and HB) at-home bleaching. Two buccal surface areas were evaluated using the Easyshade spectrophotometer: under the metal bracket (experimental) and around the bracket (control). The paired t-test, ANOVA, and Tukey tests were applied for statistical analysis. Results: Intragroup comparisons showed that in groups C, WThp and HB, there were statistically significant differences in the enamel color changes (ΔEab) between under and around the bracket areas (C - under bracket = 7.97 ± 2.35, around bracket = 2.86 ± 0.81, p< 0.01; WThp - under bracket = 4.69 ± 2.98, around bracket = 2.05 ± 1.41, p< 0.01; HB - under bracket = 7.41 ± 2.89, around bracket: 9.86 ± 3.32, p= 0.02). Groups WTsi, OB and HB presented similar perception of tooth whiteness (ΔWID) between the tested areas. Intergroup comparisons demonstrated that under the bracket area, the color change (ΔEab) was similar for all groups, except WThp (C = 7.97 ± 2.35; WTsi = 8.54 ± 3.63; WThp = 4.69 ± 2.98; OB = 9.31 ± 4.32; HB = 7.41 ± 2.89; p< 0.01). Conclusions: The dental color changes were effective for the products tested in groups WTsi, OB and HB in the presence of metallic orthodontic brackets.

  • Efficacy of Low-Level Laser Therapy in Reducing Pain in the Initial Stages of Orthodontic Treatment
    Manoel Heitor Brito, Cinthya Quagliato Nogueira, Paula Cotrin, Tiago Fialho, Renata Cristina Oliveira, Ricardo Gobbi Oliveira, Samira Salmeron, Fabrício Pinelli Valarelli, Karina Maria Salvatore Freitas, and Rodrigo Hermont Cançado

    Hindawi Limited
    Purpose. There is no consensus about the mechanism and efficacy in alleviating pain of the lower-level laser therapy (LLLT) during orthodontic treatment. This study aimed to evaluate the LLLT effectiveness clinically in reducing pain caused by orthodontic movement that occurs in the early stages of treatment. Methods. The sample consisted of 54 patients in need of orthodontic treatment divided into two groups. A 28 experimental patients group (initial mean age: 26.84 years old) was undergone gallium-aluminum-arsenide infrared laser application on 12 points for each tooth immediately after the installation of the first alignment archwire, and a 26 patients control group (initial mean age: 29.13 years old) was undergone to no pain control intervention at all. Pain intensity was measured by using a visual analog scale, which was marked pain level (mm) reported in 06, 24, 48, and 72 hours. The perception of pain (beginning, peak, decline, and absence) was evaluated by filling up a questionnaire. To compare the intensity and perception of pain between groups, a nonparametric Mann–Whitney has been performed. Results. The experimental group showed levels (mm) at 6 ( p < 0.001 ), 24 ( p = 0.004 ), and 48 hours ( p = 0.007 ) and perception of pain (hours) in the peak ( p = 0.026 ), decline ( p = 0.025 ), and absence ( p = 0.008 ) significantly lower compared to the group control. Conclusion. Low-level laser therapy is effective in reducing pain severity caused by orthodontic forces activation, and it promotes the analgesic action lasting effect during the most painful feeling time.

  • Sodium Bicarbonate Jet Reduces Contamination of Dental Implants In Vitro Without Causing Visible Surface Changes
    Edemar Junior, Marcos Zubek, Polyane Queiroz, Karina Freitas, Mariana Ortiz, and Samira Salmeron

    Quintessence Publishing
    PURPOSE The increasing use of dental implants in oral rehabilitation has contributed to the increase of cases of peri-implantitis, a complex clinical condition that persists without an ideal treatment protocol. Therefore, this study aimed to verify the decontaminating action of the sodium bicarbonate jet in vitro, using different protocols, and the presence of visible changes on the surface of dental implants. MATERIALS AND METHODS Sixteen titanium implants (BioHE, Bioconnect) were used, divided into four groups (four implants per group): sterile implants (S)-negative control; implants contaminated with oral biofilm (C)-positive control; and implants contaminated with oral biofilm and decontaminated with a sodium bicarbonate jet for 30 seconds (J30) or 60 seconds (J60). The implants of groups C, J30, and J60 were contaminated in vitro with oral biofilm, then groups J30 and J60 received the respective decontamination treatments. Microbiologic analysis was performed by counting the colony-forming units (CFUs), and a qualitative descriptive analysis of the implant surface was performed after microbiologic analysis using scanning electron microscopy (SEM). Statistical analysis included one-way analysis of variance (ANOVA) and Tukey tests and the independent t test, with a .05 significance level. RESULTS There was a significant reduction (P < .01) in the number of CFUs in groups J30 (3.63 × 106 ± 0.32) and J60 (2.74 × 106 ± 0.21) compared with group C (5.05 × 106 ± 0.43). Both decontaminated groups were statistically different from group S, which did not show bacterial growth (P < .01). When groups J30 and J60 were compared, there was also a significant difference between them (P < .01), and the group J60 showed greater decontaminating potential. The descriptive qualitative analysis did not show any visible changes on the surface of the implants. CONCLUSION The sodium bicarbonate jet was effective in decontaminating titanium implants in vitro, causing no visible damage to the implant surface.

  • Stability of transversal correction with hybrid maxillary expansion appliance in bone and tegumental piriformis opening in relation to bone age and maturation of the midpalatal suture
    V. de Marco, K. Freitas, and R. de Castro

    Medicina Oral, S.L.
    Background To evaluate the stability of the transverse correction with a hybrid maxillary expansion appliance in the bone and tegumental piriformis opening in relation to bone age and maturation of the midpalatal suture (MPS). Material and Methods 15 patients with a mean initial age of 14.9 years (SD=1.50), 7 (46.7%) were female and 8 (53.3%) were male, treated with a hybrid maxillary expander. Cone beam computed tomographic (CBCT) images were collected in three phases: T1 (orthodontic records), T2 (21.33 days (SD=10.68) after the end of expansion screw activation) and T3 after 9.13 months (DP=2.41) after the expansion screw was activated. In CBCT, measurements were performed in the nasal cavity considering the tegumental piriform opening (sagittal-axial sections) and bone (sagittal-axial-coronal sections) and the stage of MPS maturation (sagittal-axial sections). Repeated measures ANOVA was used for continuous variables and Friedman’s ANOVA for the ordinal variable followed by Bonferroni’s tests for p<0.001, in relation to time. Results There were significant differences between T1 and T2 (p=0.041), between T2 and T3 (p<0.001) and between T1 and T3 (p=0.041). Regarding bone age by cervical vertebrae maturation, 20% were in stage CS3, 40% in stage CS4, 26.7% in stage CS5 and 13.3% in stage CS6. There was a significant increase in tegumental piriformis opening between T1 (M=32.19, SD=3.79) and T2 (M=34.82, SD=2.81) (p=0.008), followed by a significant decrease in T3 (M=34.64, SD=2.73) (p=0.021), as well as in the opening of the bone piriform, between T1 (M=21.30, SD=2.47) and T2 (M=25.35, SD=2.21) (p<0.001), followed by a significant decrease in T3 (M=24.89, SD =2.30) (p=0.018). Conclusions The hybrid maxillary expansion appliance was effective in opening the midpalatal suture of all patients in the present study, without influence of the initial stage of MPS maturation and bone age. There was a relapse of the increase in the bone and tegumental piriform openings. Key words:Maxillary expansion, orthodontic anchorage procedures, nose.

  • Two-phase orthodontic treatment of two different types of tooth transposition in the same patient
    Marcelo Soares Correa, Flávia N Ellinger Correa, Karina Maria Salvatore de Freitas, Marcos Roberto de Freitas, Daniela Gamba Garib, and Guilherme Janson

    SAGE Publications
    Orthodontic treatment is thoroughly planned considering the patient’s facial and dental characteristics, the main complaint, treatment time and the orthodontist’s experience. Transposition is a form of ectopia, in which two adjacent teeth exchange positions in the dental arch. Transposition can be partial or complete. This article reports the treatment of a female patient with two kinds of tooth transposition managed in the mixed and permanent dentitions. A girl, aged eight years and three months, came to routine paediatric consultation with an ectopic permanent mandibular left lateral incisor in the mixed dentition. Radiographic analysis indicated partial transposition of the permanent mandibular left lateral incisor and canine (Md.L2.C), and development of a complete tooth transposition between the permanent maxillary right first pre-molar and canine (Mx.C.P1). The patient was treated in two phases. The first, in the mixed dentition, and the second, in the permanent dentition with a three-year follow-up between them. These challenging treatment approaches are described in detail, including the mechanics used. The key points of this treatment were early diagnosis of the ectopic mandibular lateral incisor, use of light forces and interphase patient follow-up. These determined the best time to start the second treatment phase, enabling achievement of aesthetic and functional outcomes, and the results remained stable one year after the end of orthodontic treatment.

  • Smile attractiveness in class III patients after orthodontic camouflage or orthognathic surgery
    Gabriela Martins Reis, Daniel Salvatore de Freitas, Renata Cristina Oliveira, Ricardo Cesar Gobbi de Oliveira, Célia Regina Maio Pinzan-Vercelino, Karina Maria Salvatore Freitas, and Fabricio Pinelli Valarelli

    Springer Science and Business Media LLC

RECENT SCHOLAR PUBLICATIONS

  • Third Molar Comparison in Class I and II Extraction and Non-extraction Orthodontic Treatment: A Retrospective Longitudinal Study
    D Pea-Reyes, JQ Freitas, KMS Freitas, SA Bellini-Pereira, ...
    Turkish journal of orthodontics 37 (1), 7-13 2024

  • Smile attractiveness in patients treated with or without 4 premolar extractions: A 36-year follow-up
    GDA Ros, GEB Vallejo, RM Peloso, CM Gambardela-Tkacz, P Cotrin, ...
    American Journal of Orthodontics and Dentofacial Orthopedics 2024

  • Assessment of patients’ knowledge and preferences for the use of orthodontic aligners
    J Paim, LFD Souza, T Fialho, DBM Borba, KMS Freitas, P Cotrin, VB Neis, ...
    Journal of Orthodontics, 14653125241229456 2024

  • Comparison of the efficiency of initial dental alignment with Invisalign aligners changed every 7 or 14 days in mature adults: Randomized clinical trial
    T Fialho, KMS de Freitas, ETB Ohira, JEP de Souza, RCG de Oliveira, ...
    Orthodontics & Craniofacial Research 2024

  • Orientaes de higiene para os aparelhos expansores de maxila dentossuportados, dentomucossuportados e dento-osseossuportados.
    J de Arajo GURGEL, CR Maio PINZAN-VERCELINO, ...
    Clinical Orthodontics 23 (1) 2024

  • Long-term profile attractiveness of patients with Class I and II malocclusion treated with and without extractions: A 35-year follow-up
    GB Vallejo, GDA Ros, RM Peloso, CM Gambardela-Tkacz, P Cotrin, ...
    American Journal of Orthodontics and Dentofacial Orthopedics 2024

  • Ozonated Water Promotes in vitro Decontamination of Dental Implants Surface
    RB Rosado, EJ Cruz, TP de Souza, KMS Freitas, MA Lopes Ortiz, ...
    Ozone: Science & Engineering 46 (1), 78-83 2024

  • Comparison of maxillary transversal changes between auxiliary beta‐titanium expansion arch and miniscrew‐assisted rapid palatal expansion
    LHB Sader, G Sicola, CM Marin Ramirez, A Otazu, DM Torres, P Cotrin, ...
    Orthodontics & Craniofacial Research 2023

  • Revista Uning (Online)
    I Romani
    Centro Universitrio Uning-Uning 2023

  • The Influence of Occlusal Adjustment on Long-term Post-treatment Stability of Orthodontic Treatment
    MF Bonadio, P Cotrin, CM Marn Ramirez, T Fialho, W da Silva Moura, ...
    The Open Dentistry Journal 17 (1) 2023

  • Avaliao da posio anteroposterior dos incisivos superiores e sua influncia na atratividade facial.
    JG de OLIVEIRA FILHO, KM Salvatore FREITAS, ...
    Clinical Orthodontics 22 (5) 2023

  • Maternal Risk Factors Associated with Negative COVID-19 Outcomes and Their Relation to Socioeconomic Indicators in Brazil
    HF Ribeiro, MD de Barros Carvalho, FC Pelloso, L Santos, ...
    Healthcare 11 (14), 2072 2023

  • Mandibular incisor extraction treatment in a young patient with Friedreich’s ataxia: A case report.
    F Jorge SAAB, T FIALHO, R Chicarelli TREVISI, F Pinelli VALARELLI, ...
    Clinical Orthodontics 22 (3) 2023

  • Queries regarding the effects of the Forsus fatigue-resistant device and mandibular anterior repositioning appliance Response
    C Nogueira, K de Freitas
    AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS 163 (5), 589-590 2023

  • Evaluation of the attractiveness of lips with different volumes after filling with hyaluronic acid
    PM de Queiroz Hernandez, P Cotrin, FP Valarelli, RCG de Oliveira, ...
    Scientific Reports 13 (1), 4589 2023

  • Incisor irregularity and dental arch dimensions changes in subjects with different severity of anterior crowding: a 37-year follow-up
    CM Gambardela-Tkacz, G Alcaraz, P Cotrin, KMS de Freitas, W Moura, ...
    Progress in Orthodontics 24 (1), 10 2023

  • Mandibular asymmetry retreatment with minimal presurgical orthodontic preparation and fully customized lingual orthodontics: A case report with new possibilities using blender
    PGO Pereira, SA Bellini-Pereira, D Dahs, DP e Souza, KMS Freitas, ...
    International Orthodontics 21 (1), 100724 2023

  • Correo da inclinao frontal do plano oclusal com utilizao de mini-implantes
    DBM Borba, K Freitas, PPC Silva, LO Pinheiro, FR Cunha, FP Valarelli
    Ortho Sci., Orthod. sci. pract, 26-33 2023

  • COMPARISON OF CLASS III MALOCCLUSION TREATMENT CHANGES WITH TWO PRESCRIPTIONS OF PREADJUSTED BRACKETS
    D Vieira, P Cotrin, CZ Angheben, KMS de Freitas, RH Canado, ...
    Revista de Cincias Mdicas e Biolgicas 22 (4), 651-659 2023

  • Tratamento de uma m ocluso de Classe II com propulsor mandibular Forsus associado trao de canino inferior impactado devido ao odontoma–relato de caso
    AA Bonissoni, DBM Borba, T Fialho, FP Valarelli, K Freitas, P Cotrin
    Ortho Sci., Orthod. sci. pract, 64-73 2023

MOST CITED SCHOLAR PUBLICATIONS

  • Upper and lower pharyngeal airways in subjects with Class I and Class II malocclusions and different growth patterns
    MR de Freitas, NMPV Alcazar, G Janson, KMS de Freitas, JFC Henriques
    American journal of orthodontics and dentofacial orthopedics 130 (6), 742-745 2006
    Citations: 303

  • How does the quarantine resulting from COVID-19 impact dental appointments and patient anxiety levels?
    RM Peloso, NIP Pini, D Sundfeld Neto, AA Mori, RCG Oliveira, ...
    Brazilian oral research 34, e84 2020
    Citations: 154

  • Impact of coronavirus pandemic in appointments and anxiety/concerns of patients regarding orthodontic treatment
    P Cotrin, RM Peloso, RC Oliveira, RCG de Oliveira, NIP Pini, FP Valarelli, ...
    Orthodontics & craniofacial research 23 (4), 455-461 2020
    Citations: 148

  • COVID-19 pandemic and pediatric dentistry: Fear, eating habits and parent’s oral health perceptions
    R Campagnaro, G de Oliveira Collet, MP de Andrade, JPSL Salles, ...
    Children and youth services review 118, 105469 2020
    Citations: 133

  • Postretention relapse of mandibular anterior crowding in patients treated without mandibular premolar extraction
    KMS Freitas, MR de Freitas, JFC Henriques, A Pinzan, G Janson
    American journal of orthodontics and dentofacial orthopedics 125 (4), 480-487 2004
    Citations: 132

  • Comparative distalization effects of Jones jig and pendulum appliances
    MP Patel, G Janson, JFC Henriques, RR de Almeida, MR de Freitas, ...
    American journal of orthodontics and dentofacial orthopedics 135 (3), 336-342 2009
    Citations: 119

  • Notes from the field: concerns of health-related higher education students in Brazil pertaining to distance learning during the coronavirus pandemic
    RM Peloso, F Ferruzzi, AA Mori, DP Camacho, LCS Franzin, ...
    Evaluation & the Health Professions 43 (3), 201-203 2020
    Citations: 111

  • Prevalncia das ms ocluses em pacientes inscritos para tratamento ortodntico na Faculdade de Odontologia de Bauru-USP
    MR Freitas, DS Freitas, F Pinheiro, KMS Freitas
    Rev Fac Odontol Bauru 10 (3), 164-9 2002
    Citations: 111

  • Healthcare workers in Brazil during the COVID-19 pandemic: a cross-sectional online survey
    P Cotrin, W Moura, CM Gambardela-Tkacz, FC Pelloso, LD Santos, ...
    INQUIRY: The Journal of Health Care Organization, Provision, and Financing 2020
    Citations: 100

  • Influence of the quality of the finished occlusion on postretention occlusal relapse
    KMS de Freitas, G Janson, MR de Freitas, A Pinzan, JFC Henriques, ...
    American Journal of Orthodontics and Dentofacial Orthopedics 132 (4), 428 2007
    Citations: 100

  • Dental care during COVID-19 outbreak: A web-based survey
    M Faccini, F Ferruzzi, AA Mori, GC Santin, RC Oliveira, RCG de Oliveira, ...
    European journal of dentistry 14 (S 01), S14-S19 2020
    Citations: 86

  • Stability of anterior open-bite treatment with occlusal adjustment
    G Janson, MV Crepaldi, KMS Freitas, MR de Freitas, W Janson
    American journal of orthodontics and dentofacial orthopedics 138 (1), 14. e1 2010
    Citations: 84

  • A comparison of skeletal, dentoalveolar and soft tissue characteristics in white and black Brazilian subjects
    LMA Freitas, KMS Freitas, A Pinzan, G Janson, MR Freitas
    Journal of Applied Oral Science 18, 135-142 2010
    Citations: 76

  • Predisposing factors to severe external root resorption associated to orthodontic treatment
    GV Picano, KMS Freitas, RH Canado, FP Valarelli, PRB Picano, ...
    Dental press journal of orthodontics 18, 110-120 2013
    Citations: 67

  • Evaluation of maxillary buccal alveolar bone before and after orthodontic alignment without extractions: A cone beam computed tomographic study
    JF Morais, B Melsen, KMS de Freitas, N Castello Branco, DG Garib, ...
    The Angle Orthodontist 88 (6), 748-756 2018
    Citations: 66

  • Urgencies and emergencies in orthodontics during the coronavirus disease 2019 pandemic: Brazilian orthodontists' experience
    P Cotrin, RM Peloso, NIP Pini, RC Oliveira, RCG de Oliveira, FP Valarelli, ...
    American journal of orthodontics and dentofacial orthopedics 158 (5), 661-667 2020
    Citations: 60

  • Cephalometric characterization of skeletal Class II, division 1 malocclusion in white Brazilian subjects
    MR Freitas, MAC Santos, KMS Freitas, G Janson, DS Freitas, ...
    Journal of Applied Oral Science 13, 198-203 2005
    Citations: 59

  • Evaluation of anterior open-bite treatment with occlusal adjustment
    G Janson, MV Crepaldi, KMS de Freitas, MR de Freitas, W Janson
    American Journal of Orthodontics and Dentofacial Orthopedics 134 (1), 10. e1 2008
    Citations: 56

  • The use of facemasks during the COVID-19 pandemic by the Brazilian population
    P Cotrin, AC Bahls, DO da Silva, VMP Giro, CRM Pinzan-Vercelino, ...
    Journal of multidisciplinary healthcare, 1169-1178 2020
    Citations: 54

  • Postretention stability after orthodontic closure of maxillary interincisor diastemas
    JF Morais, MR Freitas, KMS Freitas, G Janson, N Castello Branco
    Journal of Applied Oral Science 22, 409-415 2014
    Citations: 53