POORNA CHANDRIKA S
@avmc.edu.in
Research Associate cum Post-Doc fellow, Department of Microbiology
Aarupadai veedu medical college and hospital
RESEARCH, TEACHING, or OTHER INTERESTS
Biotechnology, Biomaterials, Multidisciplinary, Microbiology
Scopus Publications
Scopus Publications
Poorna Chandrika Sabapathy, Sabarinathan Devaraj, Parthiban Anburajan, Amreesh Parvez, Preethi Kathirvel, and Xianghui Qi
Springer Science and Business Media LLC
Devaraj Sabarinathan, Arumugam Selva Sharma, Akwasi Akomeah Agyekum, Marimuthu Murugavelu, Poorna Chandrika Sabapathy, Shujat Ali, Hamada Hassan, Huanhuan Li, and Quansheng Chen
Elsevier BV
Radhika Chandankere, Yuvaraj Ravikumar, Hossain M. Zabed, Poorna Chandrika Sabapathy, Junhua Yun, Guoyan Zhang, and Xianghui Qi
American Chemical Society (ACS)
Rhamnolipid is the main group of biosurfactants predominantly produced by Pseudomonas aeruginosa, a ubiquitous and opportunistic pathogen, which limits its large-scale exploitation. Thus, cost-effective rhamnolipid production from a newly isolated nonpathogenic Enterobacter sp. UJS-RC was investigated. The highest rhamnolipid production (4.4 ± 0.2 g/L) was achieved in a medium constituting agroindustrial wastes (sugarcane molasses and corn steep liquor) as substrates. Rhamnolipid exhibited reduced surface tension to 72-28 mN/m with an emulsification index of 75%. The structural analyses demonstrated the presence of methoxyl, carboxyl, and hydroxyl groups in rhamnolipid. Mass spectra indicated eight rhamnolipid congeners, where dirhamnolipid (m/z 650.01) was the dominant congener. Rhamnolipid inhibited biofilm formation of Staphylococcus aureus in a dose-dependent manner, supported by scanning electron microscopy disclosing the disruption of the microcolony/exopolysaccharide matrix. Rhamnolipid's ability to generate reactive oxygen species has thrown light on the mechanism through which the killing of test bacteria may occur.
Poorna Chandrika Sabapathy, Sabarinathan Devaraj, Katharina Meixner, Parthiban Anburajan, Preethi Kathirvel, Yuvaraj Ravikumar, Hossain M. Zabed, and Xianghui Qi
Elsevier BV
Parthiban Anburajan, A. Naresh Kumar, Poorna Chandrika Sabapathy, Gi-Beom Kim, Roent Dune Cayetano, Jeong-Jun Yoon, Gopalakrishnan Kumar, and Sang-Hyoun Kim
Elsevier BV
Sabarinathan Devaraj, Poorna Chandrika Sabapathy, Lavanya Nehru, and Kathirvel Preethi
Springer Science and Business Media LLC
Sabarinathan Devaraj, Mohankumar Amirthalingam, Poorna Chandrika Sabapathy, Shanmugam Govindan, Sundararaj Palanisamy, and Preethi Kathirvel
Springer Science and Business Media LLC
Poorna Chandrika Sabapathy, Sabarinathan Devaraj, Anburajan Parthipan, and Preethi Kathirvel
Elsevier BV
Poorna Chandrika Sabapathy, Sabarinathan Devaraj, Anburajan Parthiban, Arivalagan Pugazhendhi, and Preethi Kathirvel
Elsevier BV
Poorna Chandrika Sabapathy, Sabarinathan Devaraj, Anburajan Parthiban, and Preethi Kathirvel
Informa UK Limited
ABSTRACT The potential use of parboiled rice mill effluent as a cheap substrate for the production of homopolymer and copolymer of Polyhydroxyalkanoates (PHAs) by Acinetobacter junii BP 25 was investigated for the first time. Process optimization by one factor at a time led to homopolymer polyhydroxybutyrate (PHB) production of 2.64 ± 0.18 g/l with 94.28% PHB content using a two-stage batch cultivation mode. BP 25 furthermore produced polyhydroxybutyrate-co-hydroxyvalerate (P3 (HB-co-HV)), with the addition of valeric acid as an additive to the substrate, yielding (2.56 ± 0.12 g/l dry biomass, 2.20 ± 0.15 g/l PHA) a copolymer content of 85.93%. Thus, rice mill effluent can be an effective and relatively low-cost alternative for the production of PHA, replacing the pure substrates. GRAPHICAL ABSTRACT
Devaraj Sabarinathan, Sabapathy Poorna Chandrika, Pitchaikannu Venkatraman, Murugesh Easwaran, Chandrasekaran Senbagavadivoo Sureka, and Kathirvel Preethi
Elsevier BV
Poorna Chandrika Sabapathy, Sabarinathan Devaraj, and Preethi Kathirvel
Current Science Association
Parthenium hysterophorus is considered as one of the most devastating and hazardous weed; abundantly available in several parts of the world, it is utilized as a substrate for the production of polyhydroxyalkanoates (PHA). Bacterial strain Bacillus aerophilus , isolated from oil contaminated soil, was studied for its potential to accumulate PHA. Utilizing this cheap substrate, the highest yield of PHA content obtained was 5.4 g/l PHA with 11.92 g/l cell biomass. PHA produced was extracted using sodium hypochlorite method and the polymer synthesized was characterized as polyhydroxybutyrate (P3 (HB)) by Fourier transform infrared spectroscopy and nuclear magnetic resonance analysis.
G. Kalaiarasi, Ruchi Jain, H. Puschman, S. Poorna Chandrika, K. Preethi, and R. Prabhakaran
Royal Society of Chemistry (RSC)
Four new binuclear nickel(ii) metallates showed promising antiproliferative activity against MCF-7 and HeLa cell lines and were much less toxic against HaCaT.